Result of FASTA (omim) for
pFN21AE5559
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5559, 404 aa
1>>>pF1KE5559 404 - 404 aa - 404 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.8858+/-0.000386; mu= 7.6936+/- 0.024
mean_var=224.9507+/-45.575, 0's: 0 Z-trim(120.7): 34 B-trim: 395 in 2/51
Lambda= 0.085513
statistics sampled from 36147 (36181) to 36147 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.743), E-opt: 0.2 (0.424), width: 16
Scan time: 8.870
The best scores are: opt bits E(85289)
NP_004723 (OMIM: 604111) voltage-gated potassium c ( 404) 2738 350.4 4.7e-96
NP_751891 (OMIM: 601141) voltage-gated potassium c ( 401) 1817 236.8 7.4e-62
XP_016880793 (OMIM: 604111) PREDICTED: voltage-gat ( 384) 1816 236.6 7.8e-62
XP_011522370 (OMIM: 604111) PREDICTED: voltage-gat ( 411) 1814 236.4 9.7e-62
XP_016858109 (OMIM: 601142) PREDICTED: voltage-gat ( 400) 1735 226.6 8.2e-59
XP_016858108 (OMIM: 601142) PREDICTED: voltage-gat ( 420) 1735 226.7 8.5e-59
XP_016858107 (OMIM: 601142) PREDICTED: voltage-gat ( 420) 1735 226.7 8.5e-59
NP_003462 (OMIM: 601141) voltage-gated potassium c ( 408) 1731 226.2 1.2e-58
XP_005263571 (OMIM: 601142) PREDICTED: voltage-gat ( 353) 1723 225.1 2.1e-58
NP_742128 (OMIM: 601142) voltage-gated potassium c ( 353) 1723 225.1 2.1e-58
NP_003627 (OMIM: 601142) voltage-gated potassium c ( 367) 1712 223.8 5.5e-58
NP_001186789 (OMIM: 601142) voltage-gated potassiu ( 367) 1712 223.8 5.5e-58
NP_001186790 (OMIM: 601142) voltage-gated potassiu ( 367) 1712 223.8 5.5e-58
NP_751892 (OMIM: 601141) voltage-gated potassium c ( 419) 1713 223.9 5.6e-58
XP_011511417 (OMIM: 601141) PREDICTED: voltage-gat ( 337) 1692 221.3 2.9e-57
XP_016862660 (OMIM: 601141) PREDICTED: voltage-gat ( 337) 1692 221.3 2.9e-57
XP_011540623 (OMIM: 601142) PREDICTED: voltage-gat ( 395) 1622 212.7 1.3e-54
XP_011540624 (OMIM: 601142) PREDICTED: voltage-gat ( 395) 1622 212.7 1.3e-54
NP_001186792 (OMIM: 601142) voltage-gated potassiu ( 300) 1518 199.7 7.7e-51
XP_011511418 (OMIM: 601141) PREDICTED: voltage-gat ( 334) 1508 198.5 2e-50
XP_016862661 (OMIM: 601141) PREDICTED: voltage-gat ( 295) 1498 197.3 4.2e-50
XP_011511419 (OMIM: 601141) PREDICTED: voltage-gat ( 295) 1498 197.3 4.2e-50
XP_016862662 (OMIM: 601141) PREDICTED: voltage-gat ( 295) 1498 197.3 4.2e-50
XP_016880795 (OMIM: 604111) PREDICTED: voltage-gat ( 326) 1325 176.0 1.2e-43
NP_001295151 (OMIM: 601141) voltage-gated potassiu ( 372) 996 135.4 2.2e-31
NP_001295146 (OMIM: 601141) voltage-gated potassiu ( 390) 996 135.5 2.2e-31
NP_001186791 (OMIM: 601142) voltage-gated potassiu ( 415) 990 134.7 3.9e-31
XP_016858110 (OMIM: 601142) PREDICTED: voltage-gat ( 435) 990 134.8 4e-31
XP_016880794 (OMIM: 604111) PREDICTED: voltage-gat ( 382) 973 132.6 1.6e-30
XP_016862663 (OMIM: 601141) PREDICTED: voltage-gat ( 233) 740 103.6 5.1e-22
NP_003680 (OMIM: 603418) aflatoxin B1 aldehyde red ( 359) 230 40.9 0.006
>>NP_004723 (OMIM: 604111) voltage-gated potassium chann (404 aa)
initn: 2738 init1: 2738 opt: 2738 Z-score: 1845.5 bits: 350.4 E(85289): 4.7e-96
Smith-Waterman score: 2738; 100.0% identity (100.0% similar) in 404 aa overlap (1-404:1-404)
10 20 30 40 50 60
pF1KE5 MQVSIACTEQNLRSRSSEDRLCGPRPGPGGGNGGPAGGGHGNPPGGGGSGPKARAALVPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MQVSIACTEQNLRSRSSEDRLCGPRPGPGGGNGGPAGGGHGNPPGGGGSGPKARAALVPR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 PPAPAGALRESTGRGTGMKYRNLGKSGLRVSCLGLGTWVTFGSQISDETAEDVLTVAYEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 PPAPAGALRESTGRGTGMKYRNLGKSGLRVSCLGLGTWVTFGSQISDETAEDVLTVAYEH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 GVNLFDTAEVYAAGKAERTLGNILKSKGWRRSSYVITTKIFWGGQAETERGLSRKHIIEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 GVNLFDTAEVYAAGKAERTLGNILKSKGWRRSSYVITTKIFWGGQAETERGLSRKHIIEG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 LRGSLERLQLGYVDIVFANRSDPNCPMEEIVRAMTYVINQGLALYWGTSRWGAAEIMEAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LRGSLERLQLGYVDIVFANRSDPNCPMEEIVRAMTYVINQGLALYWGTSRWGAAEIMEAY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 SMARQFNLIPPVCEQAEHHLFQREKVEMQLPELYHKIGVGSVTWYPLACGLITSKYDGRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 SMARQFNLIPPVCEQAEHHLFQREKVEMQLPELYHKIGVGSVTWYPLACGLITSKYDGRV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE5 PDTCRASIKGYQWLKDKVQSEDGKKQQAKVMDLLPVAHQLGCTVAQLAIAWCLRSEGVSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 PDTCRASIKGYQWLKDKVQSEDGKKQQAKVMDLLPVAHQLGCTVAQLAIAWCLRSEGVSS
310 320 330 340 350 360
370 380 390 400
pF1KE5 VLLGVSSAEQLIEHLGALQVLSQLTPQTVMEIDGLLGNKPHSKK
::::::::::::::::::::::::::::::::::::::::::::
NP_004 VLLGVSSAEQLIEHLGALQVLSQLTPQTVMEIDGLLGNKPHSKK
370 380 390 400
>>NP_751891 (OMIM: 601141) voltage-gated potassium chann (401 aa)
initn: 1851 init1: 1752 opt: 1817 Z-score: 1231.5 bits: 236.8 E(85289): 7.4e-62
Smith-Waterman score: 1817; 67.6% identity (84.9% similar) in 410 aa overlap (1-404:1-397)
10 20 30 40 50
pF1KE5 MQVSIACTEQNLRSRSSEDRLCGPRPGPGGGNGGPAGGGHGNPPGGGGSGPKARA-ALVP
:::::::::.::.::..:::: . . . . : ... : :. :..
NP_751 MQVSIACTEHNLKSRNGEDRLLSKQSSTA-------------PNVVNAARAKFRTVAIIA
10 20 30 40
60 70 80 90 100 110
pF1KE5 RP-----PAPAGALRESTGRGTGMKYRNLGKSGLRVSCLGLGTWVTFGSQISDETAEDVL
: : .:.:::.. :::::::::::::::::::::::::::.:::::.:: ..
NP_751 RSLGTFTPQHHISLKESTAKQTGMKYRNLGKSGLRVSCLGLGTWVTFGGQISDEVAERLM
50 60 70 80 90 100
120 130 140 150 160 170
pF1KE5 TVAYEHGVNLFDTAEVYAAGKAERTLGNILKSKGWRRSSYVITTKIFWGGQAETERGLSR
:.::: ::::::::::::::::: ::.:.:.::::::: :::::..:::.:::::::::
NP_751 TIAYESGVNLFDTAEVYAAGKAEVILGSIIKKKGWRRSSLVITTKLYWGGKAETERGLSR
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE5 KHIIEGLRGSLERLQLGYVDIVFANRSDPNCPMEEIVRAMTYVINQGLALYWGTSRWGAA
:::::::.:::.:::: :::.::::: : : ::::::::::.:::::.:.:::::::.:
NP_751 KHIIEGLKGSLQRLQLEYVDVVFANRPDSNTPMEEIVRAMTHVINQGMAMYWGTSRWSAM
170 180 190 200 210 220
240 250 260 270 280 290
pF1KE5 EIMEAYSMARQFNLIPPVCEQAEHHLFQREKVEMQLPELYHKIGVGSVTWYPLACGLITS
:::::::.:::::.:::::::::.:::::::::.::::::::::::..:: :::::.:..
NP_751 EIMEAYSVARQFNMIPPVCEQAEYHLFQREKVEVQLPELYHKIGVGAMTWSPLACGIISG
230 240 250 260 270 280
300 310 320 330 340 350
pF1KE5 KYDGRVPDTCRASIKGYQWLKDKVQSEDGKKQQAKVMDLLPVAHQLGCTVAQLAIAWCLR
:: . ::.. :::.: :::::... ::.:.::: :. :: :.:..::::. :::.:::::
NP_751 KYGNGVPESSRASLKCYQWLKERIVSEEGRKQQNKLKDLSPIAERLGCTLPQLAVAWCLR
290 300 310 320 330 340
360 370 380 390 400
pF1KE5 SEGVSSVLLGVSSAEQLIEHLGALQVLSQLTPQTVMEIDGLLGNKPHSKK
.::::::::: :. :::::.:::.::: ..: ..: :::..: :::.:::
NP_751 NEGVSSVLLGSSTPEQLIENLGAIQVLPKMTSHVVNEIDNILRNKPYSKKDYRS
350 360 370 380 390 400
>>XP_016880793 (OMIM: 604111) PREDICTED: voltage-gated p (384 aa)
initn: 1803 init1: 1803 opt: 1816 Z-score: 1231.1 bits: 236.6 E(85289): 7.8e-62
Smith-Waterman score: 2098; 87.3% identity (88.9% similar) in 378 aa overlap (59-404:7-384)
30 40 50 60 70 80
pF1KE5 GGGNGGPAGGGHGNPPGGGGSGPKARAALVPRPPAP-AGALR--ESTGRGTGMKYRNLGK
: : : .: :: : ... . .::::
XP_016 MGVAGQPTPSAFLSGPLRLLEMAAKTPSNFTKNLGK
10 20 30
90 100 110 120 130 140
pF1KE5 SGLRVSCLGLGTWVTFGSQISDETAEDVLTVAYEHGVNLFDTAEVYAAGKAERTLGNILK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGLRVSCLGLGTWVTFGSQISDETAEDVLTVAYEHGVNLFDTAEVYAAGKAERTLGNILK
40 50 60 70 80 90
150 160 170 180 190 200
pF1KE5 SKGWRRSSYVITTKIFWGGQAETERGLSRKHIIEGLRGSLERLQLGYVDIVFANRSDPNC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SKGWRRSSYVITTKIFWGGQAETERGLSRKHIIEGLRGSLERLQLGYVDIVFANRSDPNC
100 110 120 130 140 150
210 220 230 240 250 260
pF1KE5 PMEEIVRAMTYVINQGLALYWGTSRWGAAEIMEAYSMARQFNLIPPVCEQAEHHLFQREK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PMEEIVRAMTYVINQGLALYWGTSRWGAAEIMEAYSMARQFNLIPPVCEQAEHHLFQREK
160 170 180 190 200 210
270 280 290 300 310 320
pF1KE5 VEMQLPELYHKIGVGSVTWYPLACGLITSKYDGRVPDTCRASIKGYQWLKDKVQSEDGKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VEMQLPELYHKIGVGSVTWYPLACGLITSKYDGRVPDTCRASIKGYQWLKDKVQSEDGKK
220 230 240 250 260 270
330 340 350
pF1KE5 QQAKVMDLLPVAHQLGCTVAQLAI-----------------------------AWCLRSE
:::::::::::::::::::::::: :::::::
XP_016 QQAKVMDLLPVAHQLGCTVAQLAIGRTLVFRDTSEIYVVTVPHQSSFFPPLAPAWCLRSE
280 290 300 310 320 330
360 370 380 390 400
pF1KE5 GVSSVLLGVSSAEQLIEHLGALQVLSQLTPQTVMEIDGLLGNKPHSKK
::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GVSSVLLGVSSAEQLIEHLGALQVLSQLTPQTVMEIDGLLGNKPHSKK
340 350 360 370 380
>>XP_011522370 (OMIM: 604111) PREDICTED: voltage-gated p (411 aa)
initn: 1805 init1: 1805 opt: 1814 Z-score: 1229.4 bits: 236.4 E(85289): 9.7e-62
Smith-Waterman score: 1814; 93.5% identity (95.6% similar) in 294 aa overlap (59-349:7-300)
30 40 50 60 70 80
pF1KE5 GGGNGGPAGGGHGNPPGGGGSGPKARAALVPRPPAP-AGALR--ESTGRGTGMKYRNLGK
: : : .: :: : ... . .::::
XP_011 MGVAGQPTPSAFLSGPLRLLEMAAKTPSNFTKNLGK
10 20 30
90 100 110 120 130 140
pF1KE5 SGLRVSCLGLGTWVTFGSQISDETAEDVLTVAYEHGVNLFDTAEVYAAGKAERTLGNILK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGLRVSCLGLGTWVTFGSQISDETAEDVLTVAYEHGVNLFDTAEVYAAGKAERTLGNILK
40 50 60 70 80 90
150 160 170 180 190 200
pF1KE5 SKGWRRSSYVITTKIFWGGQAETERGLSRKHIIEGLRGSLERLQLGYVDIVFANRSDPNC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SKGWRRSSYVITTKIFWGGQAETERGLSRKHIIEGLRGSLERLQLGYVDIVFANRSDPNC
100 110 120 130 140 150
210 220 230 240 250 260
pF1KE5 PMEEIVRAMTYVINQGLALYWGTSRWGAAEIMEAYSMARQFNLIPPVCEQAEHHLFQREK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PMEEIVRAMTYVINQGLALYWGTSRWGAAEIMEAYSMARQFNLIPPVCEQAEHHLFQREK
160 170 180 190 200 210
270 280 290 300 310 320
pF1KE5 VEMQLPELYHKIGVGSVTWYPLACGLITSKYDGRVPDTCRASIKGYQWLKDKVQSEDGKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VEMQLPELYHKIGVGSVTWYPLACGLITSKYDGRVPDTCRASIKGYQWLKDKVQSEDGKK
220 230 240 250 260 270
330 340 350 360 370 380
pF1KE5 QQAKVMDLLPVAHQLGCTVAQLAIAWCLRSEGVSSVLLGVSSAEQLIEHLGALQVLSQLT
::::::::::::::::::::::::
XP_011 QQAKVMDLLPVAHQLGCTVAQLAIGAEPADPADSDGNRRAPGKQAAFQEVVCRGRRDPTR
280 290 300 310 320 330
>>XP_016858109 (OMIM: 601142) PREDICTED: voltage-gated p (400 aa)
initn: 1735 init1: 1735 opt: 1735 Z-score: 1176.8 bits: 226.6 E(85289): 8.2e-59
Smith-Waterman score: 1735; 73.9% identity (92.8% similar) in 333 aa overlap (72-404:64-396)
50 60 70 80 90 100
pF1KE5 NPPGGGGSGPKARAALVPRPPAPAGALRESTGRGTGMKYRNLGKSGLRVSCLGLGTWVTF
:.. ::::::::::::::::::::::::::
XP_016 LQRLREVRAAAQARNMESFLRMHGLSLDGCTAQRTGMKYRNLGKSGLRVSCLGLGTWVTF
40 50 60 70 80 90
110 120 130 140 150 160
pF1KE5 GSQISDETAEDVLTVAYEHGVNLFDTAEVYAAGKAERTLGNILKSKGWRRSSYVITTKIF
:.::.:: ::...:.::..:.::::::::::::::: .::::.:.::::::: :::::::
XP_016 GGQITDEMAEQLMTLAYDNGINLFDTAEVYAAGKAEVVLGNIIKKKGWRRSSLVITTKIF
100 110 120 130 140 150
170 180 190 200 210 220
pF1KE5 WGGQAETERGLSRKHIIEGLRGSLERLQLGYVDIVFANRSDPNCPMEEIVRAMTYVINQG
:::.::::::::::::::::..::::::: :::.::::: ::: :::: :::::.:::::
XP_016 WGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVFANRPDPNTPMEETVRAMTHVINQG
160 170 180 190 200 210
230 240 250 260 270 280
pF1KE5 LALYWGTSRWGAAEIMEAYSMARQFNLIPPVCEQAEHHLFQREKVEMQLPELYHKIGVGS
.:.:::::::.. :::::::.:::::: ::.:::::.:.:::::::.:::::.::::::.
XP_016 MAMYWGTSRWSSMEIMEAYSVARQFNLTPPICEQAEYHMFQREKVEVQLPELFHKIGVGA
220 230 240 250 260 270
290 300 310 320 330 340
pF1KE5 VTWYPLACGLITSKYDGRVPDTCRASIKGYQWLKDKVQSEDGKKQQAKVMDLLPVAHQLG
.:: :::::....:::. .: :::.:::::::::. ::.:..::::. .: .:..::
XP_016 MTWSPLACGIVSGKYDSGIPPYSRASLKGYQWLKDKILSEEGRRQQAKLKELQAIAERLG
280 290 300 310 320 330
350 360 370 380 390 400
pF1KE5 CTVAQLAIAWCLRSEGVSSVLLGVSSAEQLIEHLGALQVLSQLTPQTVMEIDGLLGNKPH
::. :::::::::.:::::::::.:.:.::.:..::.::: .:. . . :::..:::::.
XP_016 CTLPQLAIAWCLRNEGVSSVLLGASNADQLMENIGAIQVLPKLSSSIIHEIDSILGNKPY
340 350 360 370 380 390
pF1KE5 SKK
:::
XP_016 SKKDYRS
400
>>XP_016858108 (OMIM: 601142) PREDICTED: voltage-gated p (420 aa)
initn: 1735 init1: 1735 opt: 1735 Z-score: 1176.6 bits: 226.7 E(85289): 8.5e-59
Smith-Waterman score: 1735; 73.9% identity (92.8% similar) in 333 aa overlap (72-404:84-416)
50 60 70 80 90 100
pF1KE5 NPPGGGGSGPKARAALVPRPPAPAGALRESTGRGTGMKYRNLGKSGLRVSCLGLGTWVTF
:.. ::::::::::::::::::::::::::
XP_016 LQRLREVRAAAQARNMESFLRMHGLSLDGCTAQRTGMKYRNLGKSGLRVSCLGLGTWVTF
60 70 80 90 100 110
110 120 130 140 150 160
pF1KE5 GSQISDETAEDVLTVAYEHGVNLFDTAEVYAAGKAERTLGNILKSKGWRRSSYVITTKIF
:.::.:: ::...:.::..:.::::::::::::::: .::::.:.::::::: :::::::
XP_016 GGQITDEMAEQLMTLAYDNGINLFDTAEVYAAGKAEVVLGNIIKKKGWRRSSLVITTKIF
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE5 WGGQAETERGLSRKHIIEGLRGSLERLQLGYVDIVFANRSDPNCPMEEIVRAMTYVINQG
:::.::::::::::::::::..::::::: :::.::::: ::: :::: :::::.:::::
XP_016 WGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVFANRPDPNTPMEETVRAMTHVINQG
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE5 LALYWGTSRWGAAEIMEAYSMARQFNLIPPVCEQAEHHLFQREKVEMQLPELYHKIGVGS
.:.:::::::.. :::::::.:::::: ::.:::::.:.:::::::.:::::.::::::.
XP_016 MAMYWGTSRWSSMEIMEAYSVARQFNLTPPICEQAEYHMFQREKVEVQLPELFHKIGVGA
240 250 260 270 280 290
290 300 310 320 330 340
pF1KE5 VTWYPLACGLITSKYDGRVPDTCRASIKGYQWLKDKVQSEDGKKQQAKVMDLLPVAHQLG
.:: :::::....:::. .: :::.:::::::::. ::.:..::::. .: .:..::
XP_016 MTWSPLACGIVSGKYDSGIPPYSRASLKGYQWLKDKILSEEGRRQQAKLKELQAIAERLG
300 310 320 330 340 350
350 360 370 380 390 400
pF1KE5 CTVAQLAIAWCLRSEGVSSVLLGVSSAEQLIEHLGALQVLSQLTPQTVMEIDGLLGNKPH
::. :::::::::.:::::::::.:.:.::.:..::.::: .:. . . :::..:::::.
XP_016 CTLPQLAIAWCLRNEGVSSVLLGASNADQLMENIGAIQVLPKLSSSIIHEIDSILGNKPY
360 370 380 390 400 410
pF1KE5 SKK
:::
XP_016 SKKDYRS
420
>>XP_016858107 (OMIM: 601142) PREDICTED: voltage-gated p (420 aa)
initn: 1735 init1: 1735 opt: 1735 Z-score: 1176.6 bits: 226.7 E(85289): 8.5e-59
Smith-Waterman score: 1735; 73.9% identity (92.8% similar) in 333 aa overlap (72-404:84-416)
50 60 70 80 90 100
pF1KE5 NPPGGGGSGPKARAALVPRPPAPAGALRESTGRGTGMKYRNLGKSGLRVSCLGLGTWVTF
:.. ::::::::::::::::::::::::::
XP_016 LQRLREVRAAAQARNMESFLRMHGLSLDGCTAQRTGMKYRNLGKSGLRVSCLGLGTWVTF
60 70 80 90 100 110
110 120 130 140 150 160
pF1KE5 GSQISDETAEDVLTVAYEHGVNLFDTAEVYAAGKAERTLGNILKSKGWRRSSYVITTKIF
:.::.:: ::...:.::..:.::::::::::::::: .::::.:.::::::: :::::::
XP_016 GGQITDEMAEQLMTLAYDNGINLFDTAEVYAAGKAEVVLGNIIKKKGWRRSSLVITTKIF
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE5 WGGQAETERGLSRKHIIEGLRGSLERLQLGYVDIVFANRSDPNCPMEEIVRAMTYVINQG
:::.::::::::::::::::..::::::: :::.::::: ::: :::: :::::.:::::
XP_016 WGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVFANRPDPNTPMEETVRAMTHVINQG
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE5 LALYWGTSRWGAAEIMEAYSMARQFNLIPPVCEQAEHHLFQREKVEMQLPELYHKIGVGS
.:.:::::::.. :::::::.:::::: ::.:::::.:.:::::::.:::::.::::::.
XP_016 MAMYWGTSRWSSMEIMEAYSVARQFNLTPPICEQAEYHMFQREKVEVQLPELFHKIGVGA
240 250 260 270 280 290
290 300 310 320 330 340
pF1KE5 VTWYPLACGLITSKYDGRVPDTCRASIKGYQWLKDKVQSEDGKKQQAKVMDLLPVAHQLG
.:: :::::....:::. .: :::.:::::::::. ::.:..::::. .: .:..::
XP_016 MTWSPLACGIVSGKYDSGIPPYSRASLKGYQWLKDKILSEEGRRQQAKLKELQAIAERLG
300 310 320 330 340 350
350 360 370 380 390 400
pF1KE5 CTVAQLAIAWCLRSEGVSSVLLGVSSAEQLIEHLGALQVLSQLTPQTVMEIDGLLGNKPH
::. :::::::::.:::::::::.:.:.::.:..::.::: .:. . . :::..:::::.
XP_016 CTLPQLAIAWCLRNEGVSSVLLGASNADQLMENIGAIQVLPKLSSSIIHEIDSILGNKPY
360 370 380 390 400 410
pF1KE5 SKK
:::
XP_016 SKKDYRS
420
>>NP_003462 (OMIM: 601141) voltage-gated potassium chann (408 aa)
initn: 1731 init1: 1731 opt: 1731 Z-score: 1174.1 bits: 226.2 E(85289): 1.2e-58
Smith-Waterman score: 1731; 74.6% identity (91.1% similar) in 338 aa overlap (67-404:67-404)
40 50 60 70 80 90
pF1KE5 GGGHGNPPGGGGSGPKARAALVPRPPAPAGALRESTGRGTGMKYRNLGKSGLRVSCLGLG
.:.:.: ::: :::::::::::::::::
NP_003 TQPQAACKPVRPSGAAEQKYVEKFLRVHGISLQETTRAETGMAYRNLGKSGLRVSCLGLG
40 50 60 70 80 90
100 110 120 130 140 150
pF1KE5 TWVTFGSQISDETAEDVLTVAYEHGVNLFDTAEVYAAGKAERTLGNILKSKGWRRSSYVI
::::::.:::::.:: ..:.::: ::::::::::::::::: ::.:.:.::::::: ::
NP_003 TWVTFGGQISDEVAERLMTIAYESGVNLFDTAEVYAAGKAEVILGSIIKKKGWRRSSLVI
100 110 120 130 140 150
160 170 180 190 200 210
pF1KE5 TTKIFWGGQAETERGLSRKHIIEGLRGSLERLQLGYVDIVFANRSDPNCPMEEIVRAMTY
:::..:::.::::::::::::::::.:::.:::: :::.::::: : : ::::::::::.
NP_003 TTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFANRPDSNTPMEEIVRAMTH
160 170 180 190 200 210
220 230 240 250 260 270
pF1KE5 VINQGLALYWGTSRWGAAEIMEAYSMARQFNLIPPVCEQAEHHLFQREKVEMQLPELYHK
:::::.:.:::::::.: :::::::.:::::.:::::::::.:::::::::.::::::::
NP_003 VINQGMAMYWGTSRWSAMEIMEAYSVARQFNMIPPVCEQAEYHLFQREKVEVQLPELYHK
220 230 240 250 260 270
280 290 300 310 320 330
pF1KE5 IGVGSVTWYPLACGLITSKYDGRVPDTCRASIKGYQWLKDKVQSEDGKKQQAKVMDLLPV
::::..:: :::::.:..:: . ::.. :::.: :::::... ::.:.::: :. :: :.
NP_003 IGVGAMTWSPLACGIISGKYGNGVPESSRASLKCYQWLKERIVSEEGRKQQNKLKDLSPI
280 290 300 310 320 330
340 350 360 370 380 390
pF1KE5 AHQLGCTVAQLAIAWCLRSEGVSSVLLGVSSAEQLIEHLGALQVLSQLTPQTVMEIDGLL
:..::::. :::.:::::.::::::::: :. :::::.:::.::: ..: ..: :::..:
NP_003 AERLGCTLPQLAVAWCLRNEGVSSVLLGSSTPEQLIENLGAIQVLPKMTSHVVNEIDNIL
340 350 360 370 380 390
400
pF1KE5 GNKPHSKK
:::.:::
NP_003 RNKPYSKKDYRS
400
>>XP_005263571 (OMIM: 601142) PREDICTED: voltage-gated p (353 aa)
initn: 1718 init1: 1718 opt: 1723 Z-score: 1169.5 bits: 225.1 E(85289): 2.1e-58
Smith-Waterman score: 1723; 72.2% identity (91.2% similar) in 342 aa overlap (63-404:9-349)
40 50 60 70 80 90
pF1KE5 GGPAGGGHGNPPGGGGSGPKARAALVPRPPAPAGALRESTGRGTGMKYRNLGKSGLRVSC
.:: ..:: . :: :::::::::::::
XP_005 MYPESTTGSPARLSLRQTG-SPGMIYRNLGKSGLRVSC
10 20 30
100 110 120 130 140 150
pF1KE5 LGLGTWVTFGSQISDETAEDVLTVAYEHGVNLFDTAEVYAAGKAERTLGNILKSKGWRRS
::::::::::.::.:: ::...:.::..:.::::::::::::::: .::::.:.::::::
XP_005 LGLGTWVTFGGQITDEMAEQLMTLAYDNGINLFDTAEVYAAGKAEVVLGNIIKKKGWRRS
40 50 60 70 80 90
160 170 180 190 200 210
pF1KE5 SYVITTKIFWGGQAETERGLSRKHIIEGLRGSLERLQLGYVDIVFANRSDPNCPMEEIVR
: ::::::::::.::::::::::::::::..::::::: :::.::::: ::: :::: ::
XP_005 SLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVFANRPDPNTPMEETVR
100 110 120 130 140 150
220 230 240 250 260 270
pF1KE5 AMTYVINQGLALYWGTSRWGAAEIMEAYSMARQFNLIPPVCEQAEHHLFQREKVEMQLPE
:::.:::::.:.:::::::.. :::::::.:::::: ::.:::::.:.:::::::.::::
XP_005 AMTHVINQGMAMYWGTSRWSSMEIMEAYSVARQFNLTPPICEQAEYHMFQREKVEVQLPE
160 170 180 190 200 210
280 290 300 310 320 330
pF1KE5 LYHKIGVGSVTWYPLACGLITSKYDGRVPDTCRASIKGYQWLKDKVQSEDGKKQQAKVMD
:.::::::..:: :::::....:::. .: :::.:::::::::. ::.:..::::. .
XP_005 LFHKIGVGAMTWSPLACGIVSGKYDSGIPPYSRASLKGYQWLKDKILSEEGRRQQAKLKE
220 230 240 250 260 270
340 350 360 370 380 390
pF1KE5 LLPVAHQLGCTVAQLAIAWCLRSEGVSSVLLGVSSAEQLIEHLGALQVLSQLTPQTVMEI
: .:..::::. :::::::::.:::::::::.:.:.::.:..::.::: .:. . . ::
XP_005 LQAIAERLGCTLPQLAIAWCLRNEGVSSVLLGASNADQLMENIGAIQVLPKLSSSIIHEI
280 290 300 310 320 330
400
pF1KE5 DGLLGNKPHSKK
:..:::::.:::
XP_005 DSILGNKPYSKKDYRS
340 350
>>NP_742128 (OMIM: 601142) voltage-gated potassium chann (353 aa)
initn: 1718 init1: 1718 opt: 1723 Z-score: 1169.5 bits: 225.1 E(85289): 2.1e-58
Smith-Waterman score: 1723; 72.2% identity (91.2% similar) in 342 aa overlap (63-404:9-349)
40 50 60 70 80 90
pF1KE5 GGPAGGGHGNPPGGGGSGPKARAALVPRPPAPAGALRESTGRGTGMKYRNLGKSGLRVSC
.:: ..:: . :: :::::::::::::
NP_742 MYPESTTGSPARLSLRQTG-SPGMIYRNLGKSGLRVSC
10 20 30
100 110 120 130 140 150
pF1KE5 LGLGTWVTFGSQISDETAEDVLTVAYEHGVNLFDTAEVYAAGKAERTLGNILKSKGWRRS
::::::::::.::.:: ::...:.::..:.::::::::::::::: .::::.:.::::::
NP_742 LGLGTWVTFGGQITDEMAEQLMTLAYDNGINLFDTAEVYAAGKAEVVLGNIIKKKGWRRS
40 50 60 70 80 90
160 170 180 190 200 210
pF1KE5 SYVITTKIFWGGQAETERGLSRKHIIEGLRGSLERLQLGYVDIVFANRSDPNCPMEEIVR
: ::::::::::.::::::::::::::::..::::::: :::.::::: ::: :::: ::
NP_742 SLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVFANRPDPNTPMEETVR
100 110 120 130 140 150
220 230 240 250 260 270
pF1KE5 AMTYVINQGLALYWGTSRWGAAEIMEAYSMARQFNLIPPVCEQAEHHLFQREKVEMQLPE
:::.:::::.:.:::::::.. :::::::.:::::: ::.:::::.:.:::::::.::::
NP_742 AMTHVINQGMAMYWGTSRWSSMEIMEAYSVARQFNLTPPICEQAEYHMFQREKVEVQLPE
160 170 180 190 200 210
280 290 300 310 320 330
pF1KE5 LYHKIGVGSVTWYPLACGLITSKYDGRVPDTCRASIKGYQWLKDKVQSEDGKKQQAKVMD
:.::::::..:: :::::....:::. .: :::.:::::::::. ::.:..::::. .
NP_742 LFHKIGVGAMTWSPLACGIVSGKYDSGIPPYSRASLKGYQWLKDKILSEEGRRQQAKLKE
220 230 240 250 260 270
340 350 360 370 380 390
pF1KE5 LLPVAHQLGCTVAQLAIAWCLRSEGVSSVLLGVSSAEQLIEHLGALQVLSQLTPQTVMEI
: .:..::::. :::::::::.:::::::::.:.:.::.:..::.::: .:. . . ::
NP_742 LQAIAERLGCTLPQLAIAWCLRNEGVSSVLLGASNADQLMENIGAIQVLPKLSSSIIHEI
280 290 300 310 320 330
400
pF1KE5 DGLLGNKPHSKK
:..:::::.:::
NP_742 DSILGNKPYSKKDYRS
340 350
404 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 01:49:29 2016 done: Tue Nov 8 01:49:30 2016
Total Scan time: 8.870 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]