Result of FASTA (omim) for
pFN21AE5556
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5556, 374 aa
1>>>pF1KE5556 374 - 374 aa - 374 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.3319+/-0.000462; mu= 16.7741+/- 0.029
mean_var=70.7373+/-13.905, 0's: 0 Z-trim(109.5): 34 B-trim: 275 in 1/53
Lambda= 0.152493
statistics sampled from 17626 (17653) to 17626 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.551), E-opt: 0.2 (0.207), width: 16
Scan time: 7.100
The best scores are: opt bits E(85289)
NP_006351 (OMIM: 609641) eukaryotic translation in ( 374) 2414 540.6 2.1e-153
XP_011518142 (OMIM: 609641) PREDICTED: eukaryotic ( 311) 2013 452.4 6.6e-127
NP_001294858 (OMIM: 609641) eukaryotic translation ( 242) 1498 339.0 6.9e-93
NP_001157565 (OMIM: 616009) COP9 signalosome compl ( 275) 157 44.0 0.00049
XP_005253751 (OMIM: 616009) PREDICTED: COP9 signal ( 275) 157 44.0 0.00049
NP_001157566 (OMIM: 616009) COP9 signalosome compl ( 275) 157 44.0 0.00049
NP_001157567 (OMIM: 616009) COP9 signalosome compl ( 275) 157 44.0 0.00049
NP_057403 (OMIM: 616009) COP9 signalosome complex ( 275) 157 44.0 0.00049
>>NP_006351 (OMIM: 609641) eukaryotic translation initia (374 aa)
initn: 2414 init1: 2414 opt: 2414 Z-score: 2875.0 bits: 540.6 E(85289): 2.1e-153
Smith-Waterman score: 2414; 100.0% identity (100.0% similar) in 374 aa overlap (1-374:1-374)
10 20 30 40 50 60
pF1KE5 MSVPAFIDISEEDQAAELRAYLKSKGAEISEENSEGGLHVDLAQIIEACDVCLKEDDKDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MSVPAFIDISEEDQAAELRAYLKSKGAEISEENSEGGLHVDLAQIIEACDVCLKEDDKDV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 ESVMNSVVSLLLILEPDKQEALIESLCEKLVKFREGERPSLRLQLLSNLFHGMDKNTPVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 ESVMNSVVSLLLILEPDKQEALIESLCEKLVKFREGERPSLRLQLLSNLFHGMDKNTPVR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 YTVYCSLIKVAASCGAIQYIPTELDQVRKWISDWNLTTEKKHTLLRLLYEALVDCKKSDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 YTVYCSLIKVAASCGAIQYIPTELDQVRKWISDWNLTTEKKHTLLRLLYEALVDCKKSDA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 ASKVMVELLGSYTEDNASQARVDAHRCIVRALKDPNAFLFDHLLTLKPVKFLEGELIHDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 ASKVMVELLGSYTEDNASQARVDAHRCIVRALKDPNAFLFDHLLTLKPVKFLEGELIHDL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 LTIFVSAKLASYVKFYQNNKDFIDSLGLLHEQNMAKMRLLTFMGMAVENKEISFDTMQQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 LTIFVSAKLASYVKFYQNNKDFIDSLGLLHEQNMAKMRLLTFMGMAVENKEISFDTMQQE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE5 LQIGADDVEAFVIDAVRTKMVYCKIDQTQRKVVVSHSTHRTFGKQQWQQLYDTLNAWKQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 LQIGADDVEAFVIDAVRTKMVYCKIDQTQRKVVVSHSTHRTFGKQQWQQLYDTLNAWKQN
310 320 330 340 350 360
370
pF1KE5 LNKVKNSLLSLSDT
::::::::::::::
NP_006 LNKVKNSLLSLSDT
370
>>XP_011518142 (OMIM: 609641) PREDICTED: eukaryotic tran (311 aa)
initn: 2013 init1: 2013 opt: 2013 Z-score: 2399.4 bits: 452.4 E(85289): 6.6e-127
Smith-Waterman score: 2013; 100.0% identity (100.0% similar) in 311 aa overlap (64-374:1-311)
40 50 60 70 80 90
pF1KE5 SEGGLHVDLAQIIEACDVCLKEDDKDVESVMNSVVSLLLILEPDKQEALIESLCEKLVKF
::::::::::::::::::::::::::::::
XP_011 MNSVVSLLLILEPDKQEALIESLCEKLVKF
10 20 30
100 110 120 130 140 150
pF1KE5 REGERPSLRLQLLSNLFHGMDKNTPVRYTVYCSLIKVAASCGAIQYIPTELDQVRKWISD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 REGERPSLRLQLLSNLFHGMDKNTPVRYTVYCSLIKVAASCGAIQYIPTELDQVRKWISD
40 50 60 70 80 90
160 170 180 190 200 210
pF1KE5 WNLTTEKKHTLLRLLYEALVDCKKSDAASKVMVELLGSYTEDNASQARVDAHRCIVRALK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WNLTTEKKHTLLRLLYEALVDCKKSDAASKVMVELLGSYTEDNASQARVDAHRCIVRALK
100 110 120 130 140 150
220 230 240 250 260 270
pF1KE5 DPNAFLFDHLLTLKPVKFLEGELIHDLLTIFVSAKLASYVKFYQNNKDFIDSLGLLHEQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DPNAFLFDHLLTLKPVKFLEGELIHDLLTIFVSAKLASYVKFYQNNKDFIDSLGLLHEQN
160 170 180 190 200 210
280 290 300 310 320 330
pF1KE5 MAKMRLLTFMGMAVENKEISFDTMQQELQIGADDVEAFVIDAVRTKMVYCKIDQTQRKVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAKMRLLTFMGMAVENKEISFDTMQQELQIGADDVEAFVIDAVRTKMVYCKIDQTQRKVV
220 230 240 250 260 270
340 350 360 370
pF1KE5 VSHSTHRTFGKQQWQQLYDTLNAWKQNLNKVKNSLLSLSDT
:::::::::::::::::::::::::::::::::::::::::
XP_011 VSHSTHRTFGKQQWQQLYDTLNAWKQNLNKVKNSLLSLSDT
280 290 300 310
>>NP_001294858 (OMIM: 609641) eukaryotic translation ini (242 aa)
initn: 1498 init1: 1498 opt: 1498 Z-score: 1788.6 bits: 339.0 E(85289): 6.9e-93
Smith-Waterman score: 1498; 99.1% identity (99.6% similar) in 233 aa overlap (142-374:10-242)
120 130 140 150 160 170
pF1KE5 GMDKNTPVRYTVYCSLIKVAASCGAIQYIPTELDQVRKWISDWNLTTEKKHTLLRLLYEA
.: :::::::::::::::::::::::::::
NP_001 MSVPAFIDISEEDQVRKWISDWNLTTEKKHTLLRLLYEA
10 20 30
180 190 200 210 220 230
pF1KE5 LVDCKKSDAASKVMVELLGSYTEDNASQARVDAHRCIVRALKDPNAFLFDHLLTLKPVKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LVDCKKSDAASKVMVELLGSYTEDNASQARVDAHRCIVRALKDPNAFLFDHLLTLKPVKF
40 50 60 70 80 90
240 250 260 270 280 290
pF1KE5 LEGELIHDLLTIFVSAKLASYVKFYQNNKDFIDSLGLLHEQNMAKMRLLTFMGMAVENKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LEGELIHDLLTIFVSAKLASYVKFYQNNKDFIDSLGLLHEQNMAKMRLLTFMGMAVENKE
100 110 120 130 140 150
300 310 320 330 340 350
pF1KE5 ISFDTMQQELQIGADDVEAFVIDAVRTKMVYCKIDQTQRKVVVSHSTHRTFGKQQWQQLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ISFDTMQQELQIGADDVEAFVIDAVRTKMVYCKIDQTQRKVVVSHSTHRTFGKQQWQQLY
160 170 180 190 200 210
360 370
pF1KE5 DTLNAWKQNLNKVKNSLLSLSDT
:::::::::::::::::::::::
NP_001 DTLNAWKQNLNKVKNSLLSLSDT
220 230 240
>>NP_001157565 (OMIM: 616009) COP9 signalosome complex s (275 aa)
initn: 78 init1: 78 opt: 157 Z-score: 193.4 bits: 44.0 E(85289): 0.00049
Smith-Waterman score: 157; 26.0% identity (61.0% similar) in 154 aa overlap (208-357:31-177)
180 190 200 210 220 230
pF1KE5 SDAASKVMVELLGSYTEDNASQARVDAHRCIVRALKDPNAFLFDHLLTLKPVKFL-EGEL
: ..:. :....: .:: . :. : :...
NP_001 MSAEVKVTGQNQEQFLLLAKSAKGAALATLIHQVLEAPGVYVFGELLDMPNVRELAESDF
10 20 30 40 50 60
240 250 260 270 280 290
pF1KE5 IHD--LLTIFVSAKLASYVKFYQNNKDFIDSLGLLHEQNMAKMRLLTFMGMAVENKEISF
:::.:. . :.:. .: : : : . :.: :. . .:.. : : .
NP_001 ASTFRLLTVFAYGTYADYLAEARN-------LPPLTEAQKNKLRHLSVVTLAAKVKCIPY
70 80 90 100 110
300 310 320 330 340 350
pF1KE5 DTMQQELQI-GADDVEAFVIDAVRTKMVYCKIDQTQRKVVVSHSTHRTFGKQQWQQLYDT
.. . : . .. ..: .::.:: . .. ..:: .... :..: : . .:. . . :
NP_001 AVLLEALALRNVRQLEDLVIEAVYADVLRGSLDQRNQRLEVDYSIGRDIQRQDLSAIART
120 130 140 150 160 170
360 370
pF1KE5 LNAWKQNLNKVKNSLLSLSDT
:. :
NP_001 LQEWCVGCEVVLSGIEEQVSRANQHKEQQLGLKQQIESEVANLKKTIKVTTAAAAAATSQ
180 190 200 210 220 230
>>XP_005253751 (OMIM: 616009) PREDICTED: COP9 signalosom (275 aa)
initn: 78 init1: 78 opt: 157 Z-score: 193.4 bits: 44.0 E(85289): 0.00049
Smith-Waterman score: 157; 26.0% identity (61.0% similar) in 154 aa overlap (208-357:31-177)
180 190 200 210 220 230
pF1KE5 SDAASKVMVELLGSYTEDNASQARVDAHRCIVRALKDPNAFLFDHLLTLKPVKFL-EGEL
: ..:. :....: .:: . :. : :...
XP_005 MSAEVKVTGQNQEQFLLLAKSAKGAALATLIHQVLEAPGVYVFGELLDMPNVRELAESDF
10 20 30 40 50 60
240 250 260 270 280 290
pF1KE5 IHD--LLTIFVSAKLASYVKFYQNNKDFIDSLGLLHEQNMAKMRLLTFMGMAVENKEISF
:::.:. . :.:. .: : : : . :.: :. . .:.. : : .
XP_005 ASTFRLLTVFAYGTYADYLAEARN-------LPPLTEAQKNKLRHLSVVTLAAKVKCIPY
70 80 90 100 110
300 310 320 330 340 350
pF1KE5 DTMQQELQI-GADDVEAFVIDAVRTKMVYCKIDQTQRKVVVSHSTHRTFGKQQWQQLYDT
.. . : . .. ..: .::.:: . .. ..:: .... :..: : . .:. . . :
XP_005 AVLLEALALRNVRQLEDLVIEAVYADVLRGSLDQRNQRLEVDYSIGRDIQRQDLSAIART
120 130 140 150 160 170
360 370
pF1KE5 LNAWKQNLNKVKNSLLSLSDT
:. :
XP_005 LQEWCVGCEVVLSGIEEQVSRANQHKEQQLGLKQQIESEVANLKKTIKVTTAAAAAATSQ
180 190 200 210 220 230
>>NP_001157566 (OMIM: 616009) COP9 signalosome complex s (275 aa)
initn: 78 init1: 78 opt: 157 Z-score: 193.4 bits: 44.0 E(85289): 0.00049
Smith-Waterman score: 157; 26.0% identity (61.0% similar) in 154 aa overlap (208-357:31-177)
180 190 200 210 220 230
pF1KE5 SDAASKVMVELLGSYTEDNASQARVDAHRCIVRALKDPNAFLFDHLLTLKPVKFL-EGEL
: ..:. :....: .:: . :. : :...
NP_001 MSAEVKVTGQNQEQFLLLAKSAKGAALATLIHQVLEAPGVYVFGELLDMPNVRELAESDF
10 20 30 40 50 60
240 250 260 270 280 290
pF1KE5 IHD--LLTIFVSAKLASYVKFYQNNKDFIDSLGLLHEQNMAKMRLLTFMGMAVENKEISF
:::.:. . :.:. .: : : : . :.: :. . .:.. : : .
NP_001 ASTFRLLTVFAYGTYADYLAEARN-------LPPLTEAQKNKLRHLSVVTLAAKVKCIPY
70 80 90 100 110
300 310 320 330 340 350
pF1KE5 DTMQQELQI-GADDVEAFVIDAVRTKMVYCKIDQTQRKVVVSHSTHRTFGKQQWQQLYDT
.. . : . .. ..: .::.:: . .. ..:: .... :..: : . .:. . . :
NP_001 AVLLEALALRNVRQLEDLVIEAVYADVLRGSLDQRNQRLEVDYSIGRDIQRQDLSAIART
120 130 140 150 160 170
360 370
pF1KE5 LNAWKQNLNKVKNSLLSLSDT
:. :
NP_001 LQEWCVGCEVVLSGIEEQVSRANQHKEQQLGLKQQIESEVANLKKTIKVTTAAAAAATSQ
180 190 200 210 220 230
>>NP_001157567 (OMIM: 616009) COP9 signalosome complex s (275 aa)
initn: 78 init1: 78 opt: 157 Z-score: 193.4 bits: 44.0 E(85289): 0.00049
Smith-Waterman score: 157; 26.0% identity (61.0% similar) in 154 aa overlap (208-357:31-177)
180 190 200 210 220 230
pF1KE5 SDAASKVMVELLGSYTEDNASQARVDAHRCIVRALKDPNAFLFDHLLTLKPVKFL-EGEL
: ..:. :....: .:: . :. : :...
NP_001 MSAEVKVTGQNQEQFLLLAKSAKGAALATLIHQVLEAPGVYVFGELLDMPNVRELAESDF
10 20 30 40 50 60
240 250 260 270 280 290
pF1KE5 IHD--LLTIFVSAKLASYVKFYQNNKDFIDSLGLLHEQNMAKMRLLTFMGMAVENKEISF
:::.:. . :.:. .: : : : . :.: :. . .:.. : : .
NP_001 ASTFRLLTVFAYGTYADYLAEARN-------LPPLTEAQKNKLRHLSVVTLAAKVKCIPY
70 80 90 100 110
300 310 320 330 340 350
pF1KE5 DTMQQELQI-GADDVEAFVIDAVRTKMVYCKIDQTQRKVVVSHSTHRTFGKQQWQQLYDT
.. . : . .. ..: .::.:: . .. ..:: .... :..: : . .:. . . :
NP_001 AVLLEALALRNVRQLEDLVIEAVYADVLRGSLDQRNQRLEVDYSIGRDIQRQDLSAIART
120 130 140 150 160 170
360 370
pF1KE5 LNAWKQNLNKVKNSLLSLSDT
:. :
NP_001 LQEWCVGCEVVLSGIEEQVSRANQHKEQQLGLKQQIESEVANLKKTIKVTTAAAAAATSQ
180 190 200 210 220 230
>>NP_057403 (OMIM: 616009) COP9 signalosome complex subu (275 aa)
initn: 78 init1: 78 opt: 157 Z-score: 193.4 bits: 44.0 E(85289): 0.00049
Smith-Waterman score: 157; 26.0% identity (61.0% similar) in 154 aa overlap (208-357:31-177)
180 190 200 210 220 230
pF1KE5 SDAASKVMVELLGSYTEDNASQARVDAHRCIVRALKDPNAFLFDHLLTLKPVKFL-EGEL
: ..:. :....: .:: . :. : :...
NP_057 MSAEVKVTGQNQEQFLLLAKSAKGAALATLIHQVLEAPGVYVFGELLDMPNVRELAESDF
10 20 30 40 50 60
240 250 260 270 280 290
pF1KE5 IHD--LLTIFVSAKLASYVKFYQNNKDFIDSLGLLHEQNMAKMRLLTFMGMAVENKEISF
:::.:. . :.:. .: : : : . :.: :. . .:.. : : .
NP_057 ASTFRLLTVFAYGTYADYLAEARN-------LPPLTEAQKNKLRHLSVVTLAAKVKCIPY
70 80 90 100 110
300 310 320 330 340 350
pF1KE5 DTMQQELQI-GADDVEAFVIDAVRTKMVYCKIDQTQRKVVVSHSTHRTFGKQQWQQLYDT
.. . : . .. ..: .::.:: . .. ..:: .... :..: : . .:. . . :
NP_057 AVLLEALALRNVRQLEDLVIEAVYADVLRGSLDQRNQRLEVDYSIGRDIQRQDLSAIART
120 130 140 150 160 170
360 370
pF1KE5 LNAWKQNLNKVKNSLLSLSDT
:. :
NP_057 LQEWCVGCEVVLSGIEEQVSRANQHKEQQLGLKQQIESEVANLKKTIKVTTAAAAAATSQ
180 190 200 210 220 230
374 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 01:47:43 2016 done: Tue Nov 8 01:47:44 2016
Total Scan time: 7.100 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]