Result of FASTA (ccds) for
pFN21AE5544
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5544, 381 aa
1>>>pF1KE5544 381 - 381 aa - 381 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.6976+/-0.00111; mu= 9.2698+/- 0.066
mean_var=102.7236+/-20.347, 0's: 0 Z-trim(105.1): 75 B-trim: 0 in 0/49
Lambda= 0.126543
statistics sampled from 8184 (8231) to 8184 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.629), E-opt: 0.2 (0.253), width: 16
Scan time: 2.830
The best scores are: opt bits E(32554)
CCDS5875.1 TRPV5 gene_id:56302|Hs108|chr7 ( 729) 2491 465.9 5e-131
CCDS5874.2 TRPV6 gene_id:55503|Hs108|chr7 ( 765) 1912 360.2 3.5e-99
CCDS32576.1 TRPV2 gene_id:51393|Hs108|chr17 ( 764) 324 70.3 6.5e-12
>>CCDS5875.1 TRPV5 gene_id:56302|Hs108|chr7 (729 aa)
initn: 2491 init1: 2491 opt: 2491 Z-score: 2465.8 bits: 465.9 E(32554): 5e-131
Smith-Waterman score: 2491; 100.0% identity (100.0% similar) in 374 aa overlap (1-374:1-374)
10 20 30 40 50 60
pF1KE5 MGGFLPKAEGPGSQLQKLLPSFLVREQDWDQHLDKLHMLQQKRILESPLLRASKENDLSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 MGGFLPKAEGPGSQLQKLLPSFLVREQDWDQHLDKLHMLQQKRILESPLLRASKENDLSV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 LRQLLLDCTCDVRQRGALGETALHIAALYDNLEAALVLMEAAPELVFEPTTCEAFAGQTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 LRQLLLDCTCDVRQRGALGETALHIAALYDNLEAALVLMEAAPELVFEPTTCEAFAGQTA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 LHIAVVNQNVNLVRALLTRRASVSARATGTAFRHSPRNLIYFGEHPLSFAACVNSEEIVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 LHIAVVNQNVNLVRALLTRRASVSARATGTAFRHSPRNLIYFGEHPLSFAACVNSEEIVR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 LLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDGHGDHLQPLDLVPNHQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 LLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDGHGDHLQPLDLVPNHQG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 LTPFKLAGVEGNTVMFQHLMQKRRHIQWTYGPLTSILYDLTEIDSWGEELSFLELVVSSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 LTPFKLAGVEGNTVMFQHLMQKRRHIQWTYGPLTSILYDLTEIDSWGEELSFLELVVSSD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE5 KREARQILEQTPVKELVSFKWNKYGRPYFCILAALYLLYMICFTTCCVYRPLKFRGGNRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 KREARQILEQTPVKELVSFKWNKYGRPYFCILAALYLLYMICFTTCCVYRPLKFRGGNRT
310 320 330 340 350 360
370 380
pF1KE5 HSRDITILQQKLLQVILLRRG
::::::::::::::
CCDS58 HSRDITILQQKLLQEAYETREDIIRLVGELVSIVGAVIILLLEIPDIFRVGASRYFGKTI
370 380 390 400 410 420
>>CCDS5874.2 TRPV6 gene_id:55503|Hs108|chr7 (765 aa)
initn: 1912 init1: 1912 opt: 1912 Z-score: 1894.2 bits: 360.2 E(32554): 3.5e-99
Smith-Waterman score: 1912; 77.8% identity (89.0% similar) in 374 aa overlap (1-374:41-414)
10 20 30
pF1KE5 MGGFLPKAEGPGSQLQKLLPSFLVREQDWD
:: ::: .: : . . .. :...:
CCDS58 ALGGADVAPRLSPVRVWPRPQAPKEPALHPMGLSLPKEKGLILCLWSKFCRWFQRRESWA
20 30 40 50 60 70
40 50 60 70 80 90
pF1KE5 QHLDKLHMLQQKRILESPLLRASKENDLSVLRQLLLDCTCDVRQRGALGETALHIAALYD
: :. ..:::::: ::::: :.:.::...: .:: : :.::::.::::::::::::
CCDS58 QSRDEQNLLQQKRIWESPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYD
80 90 100 110 120 130
100 110 120 130 140 150
pF1KE5 NLEAALVLMEAAPELVFEPTTCEAFAGQTALHIAVVNQNVNLVRALLTRRASVSARATGT
:::::.::::::::::::: : : . :::::::::::::.:::::::.::::::::::::
CCDS58 NLEAAMVLMEAAPELVFEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGT
140 150 160 170 180 190
160 170 180 190 200 210
pF1KE5 AFRHSPRNLIYFGEHPLSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKT
:::.:: :::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 AFRRSPCNLIYFGEHPLSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKT
200 210 220 230 240 250
220 230 240 250 260 270
pF1KE5 FACQMYNLLLSYDGHGDHLQPLDLVPNHQGLTPFKLAGVEGNTVMFQHLMQKRRHIQWTY
::::::::::::: :::::::::::::::::::::::::::::::::::::::.: ::::
CCDS58 FACQMYNLLLSYDRHGDHLQPLDLVPNHQGLTPFKLAGVEGNTVMFQHLMQKRKHTQWTY
260 270 280 290 300 310
280 290 300 310 320 330
pF1KE5 GPLTSILYDLTEIDSWGEELSFLELVVSSDKREARQILEQTPVKELVSFKWNKYGRPYFC
::::: ::::::::: :.: :.:::.... ::::::::.:::::::::.::..:::::::
CCDS58 GPLTSTLYDLTEIDSSGDEQSLLELIITTKKREARQILDQTPVKELVSLKWKRYGRPYFC
320 330 340 350 360 370
340 350 360 370 380
pF1KE5 ILAALYLLYMICFTTCCVYRPLKFRGGNRTHSRDITILQQKLLQVILLRRG
.:.:.::::.:::: ::.::::: : .::: :: :.:::::::
CCDS58 MLGAIYLLYIICFTMCCIYRPLKPRTNNRTSPRDNTLLQQKLLQEAYMTPKDDIRLVGEL
380 390 400 410 420 430
CCDS58 VTVIGAIIILLVEVPDIFRMGVTRFFGQTILGGPFHVLIITYAFMVLVTMVMRLISASGE
440 450 460 470 480 490
>>CCDS32576.1 TRPV2 gene_id:51393|Hs108|chr17 (764 aa)
initn: 402 init1: 180 opt: 324 Z-score: 327.4 bits: 70.3 E(32554): 6.5e-12
Smith-Waterman score: 454; 34.5% identity (61.6% similar) in 307 aa overlap (76-351:113-413)
50 60 70 80 90 100
pF1KE5 ESPLLRASKENDLSVLRQLLLDCTCDVRQRGALGETALHIAALY--DNLEAALV-LME--
:. :.: : :.: :...: .. :..
CCDS32 VSRGVPEDLAGLPEYLSKTSKYLTDSEYTEGSTGKTCLMKAVLNLKDGVNACILPLLQID
90 100 110 120 130 140
110 120 130 140 150
pF1KE5 ---AAPE-LVFEPTTCEAFAGQTALHIAVVNQNVNLVRALLTRRASVSARATGTAFRHSP
. :. :: : . . :..:::::. ..... :. :. :.: ::: : :...
CCDS32 RDSGNPQPLVNAQCTDDYYRGHSALHIAIEKRSLQCVKLLVENGANVHARACGRFFQKGQ
150 160 170 180 190 200
160 170 180 190 200 210
pF1KE5 RNLIYFGEHPLSFAACVNSEEIVRLLIEHG---ADIRAQDSLGNTVLHILILQPNKTFAC
. .:::: :::.:::... ..: :.:. :...: :: :::::: :.. ...
CCDS32 GTCFYFGELPLSLAACTKQWDVVSYLLENPHQPASLQATDSQGNTVLHALVMISDNS--A
210 220 230 240 250 260
220 230 240 250 260
pF1KE5 QMYNLLLS-YDG---HGDHLQP---LDLVPNHQGLTPFKLAGVEGNTVMFQHLMQK----
. :. : ::: : .: : :. . : : :::.:::. ::. .:.:..:.
CCDS32 ENIALVTSMYDGLLQAGARLCPTVQLEDIRNLQDLTPLKLAAKEGKIEIFRHILQREFSG
270 280 290 300 310 320
270 280 290 300 310
pF1KE5 -----RRHIQWTYGPLTSILYDLTEIDSWGEELSFLELVV---SSDKREARQILEQTPVK
:. .: :::. ::::. .:: :: : ::... .: .:. .:: :..
CCDS32 LSHLSRKFTEWCYGPVRVSLYDLASVDS-CEENSVLEIIAFHCKSPHRHRMVVLE--PLN
330 340 350 360 370
320 330 340 350 360 370
pF1KE5 ELVSFKWNKYGRPYFCILAALYLLYMICFTTCCVYRPLKFRGGNRTHSRDITILQQKLLQ
.:.. ::. : : . :.::. ::. ..:
CCDS32 KLLQAKWDLLI-PKFFLNFLCNLIYMFIFTAVAYHQPTLKKQAAPHLKAEVGNSMLLTGH
380 390 400 410 420 430
380
pF1KE5 VILLRRG
CCDS32 ILILLGGIYLLVGQLWYFWRRHVFIWISFIDSYFEILFLFQALLTVVSQVLCFLAIEWYL
440 450 460 470 480 490
381 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 01:40:42 2016 done: Tue Nov 8 01:40:42 2016
Total Scan time: 2.830 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]