Result of FASTA (omim) for
pFN21AE5542
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5542, 365 aa
1>>>pF1KE5542 365 - 365 aa - 365 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.4383+/-0.000443; mu= 16.4857+/- 0.027
mean_var=85.6317+/-18.426, 0's: 0 Z-trim(111.2): 55 B-trim: 764 in 2/53
Lambda= 0.138598
statistics sampled from 19745 (19790) to 19745 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.604), E-opt: 0.2 (0.232), width: 16
Scan time: 6.020
The best scores are: opt bits E(85289)
NP_116564 (OMIM: 300319) nuclear RNA export factor ( 365) 2451 500.3 2.7e-141
NP_071336 (OMIM: 300315) nuclear RNA export factor ( 626) 1809 372.2 1.8e-102
NP_006353 (OMIM: 602647) nuclear RNA export factor ( 619) 1199 250.2 9.4e-66
NP_001074960 (OMIM: 602647) nuclear RNA export fac ( 356) 990 208.2 2.3e-53
NP_071335 (OMIM: 300316) nuclear RNA export factor ( 531) 807 171.7 3.3e-42
>>NP_116564 (OMIM: 300319) nuclear RNA export factor 5 [ (365 aa)
initn: 2451 init1: 2451 opt: 2451 Z-score: 2657.6 bits: 500.3 E(85289): 2.7e-141
Smith-Waterman score: 2451; 100.0% identity (100.0% similar) in 365 aa overlap (1-365:1-365)
10 20 30 40 50 60
pF1KE5 MRRNTQDENMRKWFKVTIPYGIKYDKAWLMNSIQSNCSVPFTPVDFHYIRNRACFFVQVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 MRRNTQDENMRKWFKVTIPYGIKYDKAWLMNSIQSNCSVPFTPVDFHYIRNRACFFVQVA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 SAASALKDVSYKIYDDENQKICIFVSHFTAPYSVKNKLKPGQMEMLKLTMNKRYNVSQQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 SAASALKDVSYKIYDDENQKICIFVSHFTAPYSVKNKLKPGQMEMLKLTMNKRYNVSQQA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 LDLQNLRFDPDLMGRDIDIILNRRNCMAATLKITERNFPELLSLNLCNNKLYQLDGLSDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 LDLQNLRFDPDLMGRDIDIILNRRNCMAATLKITERNFPELLSLNLCNNKLYQLDGLSDI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 TEKAPKVKTLNLSKNKLESAWELGKVKGLKLEELWLEGNPLCSTFSDQSAYVSAIRDCFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 TEKAPKVKTLNLSKNKLESAWELGKVKGLKLEELWLEGNPLCSTFSDQSAYVSAIRDCFP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 KLLRLDGRELSAPVIVDIDSSETMKPCKENFTGSETLKHLVLQFLQQSNLCKYFKDSRNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 KLLRLDGRELSAPVIVDIDSSETMKPCKENFTGSETLKHLVLQFLQQSNLCKYFKDSRNI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE5 KILKDPYLQRKLLKHTKCPRNVDSLSALPETQHDFTSILVDMWYQTVNTCFLPRAGPESQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 KILKDPYLQRKLLKHTKCPRNVDSLSALPETQHDFTSILVDMWYQTVNTCFLPRAGPESQ
310 320 330 340 350 360
pF1KE5 SLRPL
:::::
NP_116 SLRPL
>>NP_071336 (OMIM: 300315) nuclear RNA export factor 2 [ (626 aa)
initn: 2063 init1: 1809 opt: 1809 Z-score: 1960.6 bits: 372.2 E(85289): 1.8e-102
Smith-Waterman score: 1996; 81.5% identity (85.9% similar) in 389 aa overlap (1-351:112-498)
10 20 30
pF1KE5 MRRNTQDENMRKWFKVTIPYGIKYDKAWLM
: .:::: :.::::::::::::::::::
NP_071 SIRCERRMKWHSEDEIRITTWRNRKPPERKMSQNTQDGYTRNWFKVTIPYGIKYDKAWLM
90 100 110 120 130 140
40 50 60 70 80 90
pF1KE5 NSIQSNCSVPFTPVDFHYIRNRACFFVQVASAASALKDVSYKIYDDENQKICIFVSHFTA
:::::.:: ::::::::.::::::::: ::::::::::::::::::::::::::.: ::
NP_071 NSIQSHCSDRFTPVDFHYVRNRACFFVQDASAASALKDVSYKIYDDENQKICIFVNHSTA
150 160 170 180 190 200
100 110 120 130 140 150
pF1KE5 PYSVKNKLKPGQMEMLKLTMNKRYNVSQQALDLQNLRFDPDLMGRDIDIILNRRNCMAAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 PYSVKNKLKPGQMEMLKLTMNKRYNVSQQALDLQNLRFDPDLMGRDIDIILNRRNCMAAT
210 220 230 240 250 260
160 170 180 190 200 210
pF1KE5 LKITERNFPELLSLNLCNNKLYQLDGLSDITEKAPKVKTLNLSKNKLESAWELGKVKGLK
::: ::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 LKIIERNFPELLSLNLCNNKLYQLDGLSDITEKAPKVKTLNLSKNKLESAWELGKVKGLK
270 280 290 300 310 320
220 230 240 250 260 270
pF1KE5 LEELWLEGNPLCSTFSDQSAYVSAIRDCFPKLLRLDGRELSAPVIVDIDSSETMKPCKEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 LEELWLEGNPLCSTFSDQSAYVSAIRDCFPKLLRLDGRELSAPVIVDIDSSETMKPCKEN
330 340 350 360 370 380
280 290
pF1KE5 FTGSETLKHLVLQFLQQ------------------------------------SNLCKYF
::::::::::::::::: :.:::::
NP_071 FTGSETLKHLVLQFLQQYYSIYDSGDRQGLLGAYHDEACFSLAIPFDPKDSAPSSLCKYF
390 400 410 420 430 440
300 310 320 330 340 350
pF1KE5 KDSRNIKILKDPYLQRKLLKHTKCPRN-VDSLSALPETQHDFTSILVDMWYQTVNT-CFL
.::::.: ::::::. .::..:: :. ::::::::.::::..:::::.: :: ::
NP_071 EDSRNMKTLKDPYLKGELLRRTK--RDIVDSLSALPKTQHDLSSILVDVWCQTERMLCFS
450 460 470 480 490
360
pF1KE5 PRAGPESQSLRPL
NP_071 VNGVFKEVEGQSQGSVLAFTRTFIATPGSSSSLCIVNDELFVRDASPQETQSAFSIPVST
500 510 520 530 540 550
>>NP_006353 (OMIM: 602647) nuclear RNA export factor 1 i (619 aa)
initn: 1262 init1: 1199 opt: 1199 Z-score: 1301.5 bits: 250.2 E(85289): 9.4e-66
Smith-Waterman score: 1316; 54.7% identity (75.5% similar) in 384 aa overlap (5-351:111-493)
10 20 30
pF1KE5 MRRNTQDENMRKWFKVTIPYGIKYDKAWLMNSIQ
.:: . ..:::.::::: :::::::.. ::
NP_006 RRGDTWHDRDRIHVTVRRDRAPPERGGAGTSQDGTSKNWFKITIPYGRKYDKAWLLSMIQ
90 100 110 120 130 140
40 50 60 70 80 90
pF1KE5 SNCSVPFTPVDFHYIRNRACFFVQVASAASALKDVSYKIYDDENQKICIFVSHFTAPYSV
:.:::::::..::: .:: :::. ::.::::: :.::: : ::..: :... . :...
NP_006 SKCSVPFTPIEFHYENTRAQFFVEDASTASALKAVNYKILDRENRRISIIINSSAPPHTI
150 160 170 180 190 200
100 110 120 130 140 150
pF1KE5 KNKLKPGQMEMLKLTMNKRYNVSQQALDLQNLRFDPDLMGRDIDIILNRRNCMAATLKIT
:.::: :.:.::: :.:::. :::::::..:: ::::....::..::::.::::::.:
NP_006 LNELKPEQVEQLKLIMSKRYDGSQQALDLKGLRSDPDLVAQNIDVVLNRRSCMAATLRII
210 220 230 240 250 260
160 170 180 190 200 210
pF1KE5 ERNFPELLSLNLCNNKLYQLDGLSDITEKAPKVKTLNLSKNKLESAWELGKVKGLKLEEL
:.:.:::::::: ::.::.:: .:.:..:::..: :::: :.:.: :: :.::::::::
NP_006 EENIPELLSLNLSNNRLYRLDDMSSIVQKAPNLKILNLSGNELKSERELDKIKGLKLEEL
270 280 290 300 310 320
220 230 240 250 260 270
pF1KE5 WLEGNPLCSTFSDQSAYVSAIRDCFPKLLRLDGRELSAPVIVDIDSSETMKPCKENFTGS
::.:: ::.:: :::.:.::::. :::::::::.:: :. :... :. ::: .. :.
NP_006 WLDGNSLCDTFRDQSTYISAIRERFPKLLRLDGHELPPPIAFDVEAPTTLPPCKGSYFGT
330 340 350 360 370 380
280 290
pF1KE5 ETLKHLVLQFLQQ------------------------------------SNLCKYFKDSR
:.:: :::.:::: :.: .::::::
NP_006 ENLKSLVLHFLQQYYAIYDSGDRQGLLDAYHDGACCSLSIPFIPQNPARSSLAEYFKDSR
390 400 410 420 430 440
300 310 320 330 340 350
pF1KE5 NIKILKDPYLQRKLLKHTKCPRNVDSLSALPETQHDFTSILVDMWYQTVNT-CFLPRAGP
:.: :::: :. .:::::. : :. ::.:::: .:..::. :: . ::
NP_006 NVKKLKDPTLRFRLLKHTRL-NVVAFLNELPKTQHDVNSFVVDISAQTSTLLCFSVNGVF
450 460 470 480 490
360
pF1KE5 ESQSLRPL
NP_006 KEVDGKSRDSLRAFTRTFIAVPASNSGLCIVNDELFVRNASSEEIQRAFAMPAPTPSSSP
500 510 520 530 540 550
>>NP_001074960 (OMIM: 602647) nuclear RNA export factor (356 aa)
initn: 980 init1: 980 opt: 990 Z-score: 1078.9 bits: 208.2 E(85289): 2.3e-53
Smith-Waterman score: 990; 61.5% identity (85.9% similar) in 234 aa overlap (5-238:111-344)
10 20 30
pF1KE5 MRRNTQDENMRKWFKVTIPYGIKYDKAWLMNSIQ
.:: . ..:::.::::: :::::::.. ::
NP_001 RRGDTWHDRDRIHVTVRRDRAPPERGGAGTSQDGTSKNWFKITIPYGRKYDKAWLLSMIQ
90 100 110 120 130 140
40 50 60 70 80 90
pF1KE5 SNCSVPFTPVDFHYIRNRACFFVQVASAASALKDVSYKIYDDENQKICIFVSHFTAPYSV
:.:::::::..::: .:: :::. ::.::::: :.::: : ::..: :... . :...
NP_001 SKCSVPFTPIEFHYENTRAQFFVEDASTASALKAVNYKILDRENRRISIIINSSAPPHTI
150 160 170 180 190 200
100 110 120 130 140 150
pF1KE5 KNKLKPGQMEMLKLTMNKRYNVSQQALDLQNLRFDPDLMGRDIDIILNRRNCMAATLKIT
:.::: :.:.::: :.:::. :::::::..:: ::::....::..::::.::::::.:
NP_001 LNELKPEQVEQLKLIMSKRYDGSQQALDLKGLRSDPDLVAQNIDVVLNRRSCMAATLRII
210 220 230 240 250 260
160 170 180 190 200 210
pF1KE5 ERNFPELLSLNLCNNKLYQLDGLSDITEKAPKVKTLNLSKNKLESAWELGKVKGLKLEEL
:.:.:::::::: ::.::.:: .:.:..:::..: :::: :.:.: :: :.::::::::
NP_001 EENIPELLSLNLSNNRLYRLDDMSSIVQKAPNLKILNLSGNELKSERELDKIKGLKLEEL
270 280 290 300 310 320
220 230 240 250 260 270
pF1KE5 WLEGNPLCSTFSDQSAYVSAIRDCFPKLLRLDGRELSAPVIVDIDSSETMKPCKENFTGS
::.:: ::.:: :::.:. .. :
NP_001 WLDGNSLCDTFRDQSTYIRSVVACVSPPGDLHPLGG
330 340 350
>>NP_071335 (OMIM: 300316) nuclear RNA export factor 3 [ (531 aa)
initn: 710 init1: 577 opt: 807 Z-score: 878.8 bits: 171.7 E(85289): 3.3e-42
Smith-Waterman score: 922; 42.8% identity (62.6% similar) in 388 aa overlap (1-351:101-451)
10 20 30
pF1KE5 MRRNTQDENMRKWFKVTIPYGIKYDKAWLM
:. : : .. .:::.:.:.::::.. ::.
NP_071 ISPYNRKGSFRKQDQTHVNMEREQKPPERRMEGNMPDGTLGSWFKITVPFGIKYNEKWLL
80 90 100 110 120 130
40 50 60 70 80 90
pF1KE5 NSIQSNCSVPFTPVDFHYIRNRACFFVQVASAASALKDVSYKIYDDENQKICIFVSHFTA
: ::..:::::.::.::: .: :::. :: : :::.:: ::.:..:.:: :::.
NP_071 NLIQNECSVPFVPVEFHYENMHASFFVENASIAYALKNVSGKIWDEDNEKISIFVNPAGI
140 150 160 170 180 190
100 110 120 130 140 150
pF1KE5 PYSVKNKLKPGQMEMLKLTMNKRYNVSQQALDLQNLRFDPDLMGRDIDIILNRRNCMAAT
:. :. .:: ..:..::.::.. .:::.:::.: : : ::...:: . : :.::::.
NP_071 PHFVHRELKSEKVEQIKLAMNQQCDVSQEALDIQRLPFYPDMVNRDTKMASNPRKCMAAS
200 210 220 230 240 250
160 170 180 190 200 210
pF1KE5 LKITERNFPELLSLNLCNNKLYQLDGLSDITEKAPKVKTLNLSKNKLESAWELGKVKGLK
: . :.:.: ..: : :. : ::..
NP_071 LDVHEENIPTVMS------------------------------------AGEMDKWKGIE
260 270
220 230 240 250 260 270
pF1KE5 LEELWLEGNPLCSTFSDQSAYVSAIRDCFPKLLRLDGRELSAPVIVDIDSSETMKPCKEN
: . .:.:.:::: :. ...: . ::::: :::.. .. .. . . :: .
NP_071 PGEKCADRSPVCTTFSDTSSNINSILELFPKLLCLDGQQSPRATLCGTEAHKRLPTCKGS
280 290 300 310 320 330
280 290
pF1KE5 FTGSETLKHLVLQFLQQ------------------------------------SNLCKYF
: ::: ::.:::::::: :..::.:
NP_071 FFGSEMLKNLVLQFLQQYYLIYDSGDRQGLLSAYHDEACFSLSIPFNPEDSAPSSFCKFF
340 350 360 370 380 390
300 310 320 330 340 350
pF1KE5 KDSRNIKILKDPYLQRKLLKHTKCPRNVDSLSALPETQHDFTSILVDMWYQTV-NTCFLP
::::::::::::::. .:::::: ::::::::.::::..:.:::::::: ::
NP_071 KDSRNIKILKDPYLRGELLKHTKLD-IVDSLSALPKTQHDLSSFLVDMWYQTEWMLCFSV
400 410 420 430 440 450
360
pF1KE5 RAGPESQSLRPL
NP_071 NGVFKEVEGQSQGSVLAFTRTFIATPGSSSSLCIVNDKLFVRDTSHQGTQSALFTLVPTA
460 470 480 490 500 510
365 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 01:39:28 2016 done: Tue Nov 8 01:39:29 2016
Total Scan time: 6.020 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]