Result of FASTA (omim) for
pFN21AE5538
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5538, 365 aa
1>>>pF1KE5538 365 - 365 aa - 365 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.7234+/-0.000412; mu= 14.0532+/- 0.026
mean_var=64.2271+/-12.969, 0's: 0 Z-trim(110.8): 139 B-trim: 183 in 1/52
Lambda= 0.160035
statistics sampled from 19066 (19215) to 19066 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.598), E-opt: 0.2 (0.225), width: 16
Scan time: 5.800
The best scores are: opt bits E(85289)
NP_004952 (OMIM: 300093) gamma-aminobutyric acid r ( 506) 2392 561.3 1.7e-159
XP_016884878 (OMIM: 300093) PREDICTED: gamma-amino ( 267) 1697 400.7 1.9e-111
XP_016884875 (OMIM: 300093) PREDICTED: gamma-amino ( 393) 1697 400.8 2.8e-111
XP_016884876 (OMIM: 300093) PREDICTED: gamma-amino ( 361) 1389 329.7 6.5e-90
NP_150092 (OMIM: 600233) gamma-aminobutyric acid r ( 467) 1234 293.9 4.9e-79
XP_011519732 (OMIM: 600233) PREDICTED: gamma-amino ( 473) 1234 293.9 4.9e-79
NP_000807 (OMIM: 137164,607681,611277) gamma-amino ( 467) 1226 292.1 1.8e-78
NP_944494 (OMIM: 137164,607681,611277) gamma-amino ( 475) 1226 292.1 1.8e-78
NP_775807 (OMIM: 137166) gamma-aminobutyric acid r ( 465) 1215 289.5 1e-77
NP_000802 (OMIM: 137143) gamma-aminobutyric acid r ( 453) 1029 246.6 8.4e-65
NP_001191195 (OMIM: 137141) gamma-aminobutyric aci ( 535) 1022 245.0 3e-64
NP_000800 (OMIM: 137141) gamma-aminobutyric acid r ( 554) 1022 245.0 3.1e-64
XP_016884877 (OMIM: 300093) PREDICTED: gamma-amino ( 313) 984 236.1 8e-62
NP_001121115 (OMIM: 137160,611136,615744) gamma-am ( 456) 982 235.7 1.6e-61
NP_001121116 (OMIM: 137160,611136,615744) gamma-am ( 456) 982 235.7 1.6e-61
NP_001121117 (OMIM: 137160,611136,615744) gamma-am ( 456) 982 235.7 1.6e-61
NP_001121120 (OMIM: 137160,611136,615744) gamma-am ( 456) 982 235.7 1.6e-61
NP_000797 (OMIM: 137160,611136,615744) gamma-amino ( 456) 982 235.7 1.6e-61
NP_000799 (OMIM: 305660) gamma-aminobutyric acid r ( 492) 982 235.7 1.7e-61
NP_000801 (OMIM: 137142) gamma-aminobutyric acid r ( 462) 979 235.0 2.6e-61
XP_005268315 (OMIM: 137142) PREDICTED: gamma-amino ( 462) 979 235.0 2.6e-61
XP_006720522 (OMIM: 137142) PREDICTED: gamma-amino ( 462) 979 235.0 2.6e-61
NP_001158509 (OMIM: 137142) gamma-aminobutyric aci ( 462) 979 235.0 2.6e-61
XP_016877548 (OMIM: 600233) PREDICTED: gamma-amino ( 355) 974 233.8 4.5e-61
XP_016877547 (OMIM: 600233) PREDICTED: gamma-amino ( 361) 974 233.8 4.5e-61
XP_016863472 (OMIM: 103780,137140) PREDICTED: gamm ( 451) 963 231.3 3.2e-60
NP_000798 (OMIM: 103780,137140) gamma-aminobutyric ( 451) 963 231.3 3.2e-60
NP_001107647 (OMIM: 103780,137140) gamma-aminobuty ( 451) 963 231.3 3.2e-60
XP_016863471 (OMIM: 103780,137140) PREDICTED: gamm ( 451) 963 231.3 3.2e-60
NP_001317619 (OMIM: 103780,137140) gamma-aminobuty ( 511) 963 231.3 3.6e-60
XP_011511977 (OMIM: 103780,137140) PREDICTED: gamm ( 511) 963 231.3 3.6e-60
XP_011529442 (OMIM: 300093) PREDICTED: gamma-amino ( 284) 942 226.4 6.1e-59
XP_016863479 (OMIM: 137166) PREDICTED: gamma-amino ( 336) 942 226.4 7.1e-59
XP_005248137 (OMIM: 103780,137140) PREDICTED: gamm ( 396) 824 199.2 1.3e-50
NP_001273756 (OMIM: 103780,137140) gamma-aminobuty ( 456) 824 199.2 1.5e-50
XP_011539496 (OMIM: 137163,613060) PREDICTED: gamm ( 465) 799 193.5 8.3e-49
NP_000803 (OMIM: 137190,617153) gamma-aminobutyric ( 474) 797 193.0 1.2e-48
NP_000806 (OMIM: 137163,613060) gamma-aminobutyric ( 452) 792 191.8 2.5e-48
XP_016856425 (OMIM: 137163,613060) PREDICTED: gamm ( 687) 791 191.7 4.3e-48
NP_001257802 (OMIM: 600233) gamma-aminobutyric aci ( 253) 785 190.2 4.5e-48
XP_016877545 (OMIM: 137142) PREDICTED: gamma-amino ( 306) 784 190.0 6.3e-48
XP_016877544 (OMIM: 137142) PREDICTED: gamma-amino ( 306) 784 190.0 6.3e-48
NP_000804 (OMIM: 600232) gamma-aminobutyric acid r ( 474) 785 190.2 8e-48
NP_068711 (OMIM: 600232) gamma-aminobutyric acid r ( 512) 785 190.2 8.5e-48
XP_006724874 (OMIM: 305660) PREDICTED: gamma-amino ( 340) 780 189.0 1.3e-47
NP_068712 (OMIM: 137192,612269,617113) gamma-amino ( 473) 780 189.1 1.8e-47
NP_001036008 (OMIM: 600421) glycine receptor subun ( 449) 771 187.0 7.1e-47
NP_006520 (OMIM: 600421) glycine receptor subunit ( 464) 771 187.0 7.3e-47
NP_000805 (OMIM: 137192,612269,617113) gamma-amino ( 473) 771 187.0 7.5e-47
NP_000162 (OMIM: 138491,149400) glycine receptor s ( 449) 767 186.1 1.4e-46
>>NP_004952 (OMIM: 300093) gamma-aminobutyric acid recep (506 aa)
initn: 2392 init1: 2392 opt: 2392 Z-score: 2984.3 bits: 561.3 E(85289): 1.7e-159
Smith-Waterman score: 2392; 99.2% identity (100.0% similar) in 365 aa overlap (1-365:1-365)
10 20 30 40 50 60
pF1KE5 MLSKVLPVFLGILLILQSRVEGPQTESKNEASSRDVVYGPQPQPLENQLLSEETKSTETE
::::::::.:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MLSKVLPVLLGILLILQSRVEGPQTESKNEASSRDVVYGPQPQPLENQLLSEETKSTETE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 TGSRVGKLPEASRILNTILSNYDHKLRPGIGEKPTVVTVEIAVNSLGPLSILDMEYTIDI
:::::::::::::::::::::::::::::::::::::::::.::::::::::::::::::
NP_004 TGSRVGKLPEASRILNTILSNYDHKLRPGIGEKPTVVTVEISVNSLGPLSILDMEYTIDI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 IFSQTWYDERLCYNDTFESLVLNGNVVSQLWIPDTFFRNSKRTHEHEITMPNQMVRIYKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 IFSQTWYDERLCYNDTFESLVLNGNVVSQLWIPDTFFRNSKRTHEHEITMPNQMVRIYKD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 GKVLYTIRMTIDAGCSLHMLRFPMDSHSCPLSFSSFSYPENEMIYKWENFKLEINEKNSW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 GKVLYTIRMTIDAGCSLHMLRFPMDSHSCPLSFSSFSYPENEMIYKWENFKLEINEKNSW
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 KLFQFDFTGVSNKTEIITTPVGDFMVMTIFFNVSRRFGYVAFQNYVPSSVTTMLSWVSFW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 KLFQFDFTGVSNKTEIITTPVGDFMVMTIFFNVSRRFGYVAFQNYVPSSVTTMLSWVSFW
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE5 IKTESAPARTSLGITSVLTMTTLGTFSRKNFPRVSYITALDFYIAICFVFCFCALLEFAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 IKTESAPARTSLGITSVLTMTTLGTFSRKNFPRVSYITALDFYIAICFVFCFCALLEFAV
310 320 330 340 350 360
pF1KE5 LNFLM
::::.
NP_004 LNFLIYNQTKAHASPKLRHPRINSRAHARTRARSRACARQHQEAFVCQIVTTEGSDGEER
370 380 390 400 410 420
>>XP_016884878 (OMIM: 300093) PREDICTED: gamma-aminobuty (267 aa)
initn: 1697 init1: 1697 opt: 1697 Z-score: 2121.7 bits: 400.7 E(85289): 1.9e-111
Smith-Waterman score: 1697; 99.6% identity (100.0% similar) in 252 aa overlap (114-365:1-252)
90 100 110 120 130 140
pF1KE5 HKLRPGIGEKPTVVTVEIAVNSLGPLSILDMEYTIDIIFSQTWYDERLCYNDTFESLVLN
::::::::::::::::::::::::::::::
XP_016 MEYTIDIIFSQTWYDERLCYNDTFESLVLN
10 20 30
150 160 170 180 190 200
pF1KE5 GNVVSQLWIPDTFFRNSKRTHEHEITMPNQMVRIYKDGKVLYTIRMTIDAGCSLHMLRFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GNVVSQLWIPDTFFRNSKRTHEHEITMPNQMVRIYKDGKVLYTIRMTIDAGCSLHMLRFP
40 50 60 70 80 90
210 220 230 240 250 260
pF1KE5 MDSHSCPLSFSSFSYPENEMIYKWENFKLEINEKNSWKLFQFDFTGVSNKTEIITTPVGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MDSHSCPLSFSSFSYPENEMIYKWENFKLEINEKNSWKLFQFDFTGVSNKTEIITTPVGD
100 110 120 130 140 150
270 280 290 300 310 320
pF1KE5 FMVMTIFFNVSRRFGYVAFQNYVPSSVTTMLSWVSFWIKTESAPARTSLGITSVLTMTTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FMVMTIFFNVSRRFGYVAFQNYVPSSVTTMLSWVSFWIKTESAPARTSLGITSVLTMTTL
160 170 180 190 200 210
330 340 350 360
pF1KE5 GTFSRKNFPRVSYITALDFYIAICFVFCFCALLEFAVLNFLM
:::::::::::::::::::::::::::::::::::::::::.
XP_016 GTFSRKNFPRVSYITALDFYIAICFVFCFCALLEFAVLNFLIYNQTKAHASPKLRHV
220 230 240 250 260
>>XP_016884875 (OMIM: 300093) PREDICTED: gamma-aminobuty (393 aa)
initn: 1697 init1: 1697 opt: 1697 Z-score: 2118.9 bits: 400.8 E(85289): 2.8e-111
Smith-Waterman score: 1697; 99.6% identity (100.0% similar) in 252 aa overlap (114-365:1-252)
90 100 110 120 130 140
pF1KE5 HKLRPGIGEKPTVVTVEIAVNSLGPLSILDMEYTIDIIFSQTWYDERLCYNDTFESLVLN
::::::::::::::::::::::::::::::
XP_016 MEYTIDIIFSQTWYDERLCYNDTFESLVLN
10 20 30
150 160 170 180 190 200
pF1KE5 GNVVSQLWIPDTFFRNSKRTHEHEITMPNQMVRIYKDGKVLYTIRMTIDAGCSLHMLRFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GNVVSQLWIPDTFFRNSKRTHEHEITMPNQMVRIYKDGKVLYTIRMTIDAGCSLHMLRFP
40 50 60 70 80 90
210 220 230 240 250 260
pF1KE5 MDSHSCPLSFSSFSYPENEMIYKWENFKLEINEKNSWKLFQFDFTGVSNKTEIITTPVGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MDSHSCPLSFSSFSYPENEMIYKWENFKLEINEKNSWKLFQFDFTGVSNKTEIITTPVGD
100 110 120 130 140 150
270 280 290 300 310 320
pF1KE5 FMVMTIFFNVSRRFGYVAFQNYVPSSVTTMLSWVSFWIKTESAPARTSLGITSVLTMTTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FMVMTIFFNVSRRFGYVAFQNYVPSSVTTMLSWVSFWIKTESAPARTSLGITSVLTMTTL
160 170 180 190 200 210
330 340 350 360
pF1KE5 GTFSRKNFPRVSYITALDFYIAICFVFCFCALLEFAVLNFLM
:::::::::::::::::::::::::::::::::::::::::.
XP_016 GTFSRKNFPRVSYITALDFYIAICFVFCFCALLEFAVLNFLIYNQTKAHASPKLRHPRIN
220 230 240 250 260 270
XP_016 SRAHARTRARSRACARQHQEAFVCQIVTTEGSDGEERPSCSAQQPPSPGSPEGPRSLCSK
280 290 300 310 320 330
>>XP_016884876 (OMIM: 300093) PREDICTED: gamma-aminobuty (361 aa)
initn: 1465 init1: 1384 opt: 1389 Z-score: 1735.2 bits: 329.7 E(85289): 6.5e-90
Smith-Waterman score: 1399; 86.9% identity (87.3% similar) in 252 aa overlap (114-365:1-220)
90 100 110 120 130 140
pF1KE5 HKLRPGIGEKPTVVTVEIAVNSLGPLSILDMEYTIDIIFSQTWYDERLCYNDTFESLVLN
:::::::::::::
XP_016 MEYTIDIIFSQTW-----------------
10
150 160 170 180 190 200
pF1KE5 GNVVSQLWIPDTFFRNSKRTHEHEITMPNQMVRIYKDGKVLYTIRMTIDAGCSLHMLRFP
:::::::::::::::::::::::::::::::::::::::::::::
XP_016 ---------------NSKRTHEHEITMPNQMVRIYKDGKVLYTIRMTIDAGCSLHMLRFP
20 30 40 50
210 220 230 240 250 260
pF1KE5 MDSHSCPLSFSSFSYPENEMIYKWENFKLEINEKNSWKLFQFDFTGVSNKTEIITTPVGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MDSHSCPLSFSSFSYPENEMIYKWENFKLEINEKNSWKLFQFDFTGVSNKTEIITTPVGD
60 70 80 90 100 110
270 280 290 300 310 320
pF1KE5 FMVMTIFFNVSRRFGYVAFQNYVPSSVTTMLSWVSFWIKTESAPARTSLGITSVLTMTTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FMVMTIFFNVSRRFGYVAFQNYVPSSVTTMLSWVSFWIKTESAPARTSLGITSVLTMTTL
120 130 140 150 160 170
330 340 350 360
pF1KE5 GTFSRKNFPRVSYITALDFYIAICFVFCFCALLEFAVLNFLM
:::::::::::::::::::::::::::::::::::::::::.
XP_016 GTFSRKNFPRVSYITALDFYIAICFVFCFCALLEFAVLNFLIYNQTKAHASPKLRHPRIN
180 190 200 210 220 230
XP_016 SRAHARTRARSRACARQHQEAFVCQIVTTEGSDGEERPSCSAQQPPSPGSPEGPRSLCSK
240 250 260 270 280 290
>>NP_150092 (OMIM: 600233) gamma-aminobutyric acid recep (467 aa)
initn: 1232 init1: 1232 opt: 1234 Z-score: 1540.0 bits: 293.9 E(85289): 4.9e-79
Smith-Waterman score: 1234; 54.8% identity (86.2% similar) in 312 aa overlap (52-363:28-339)
30 40 50 60 70 80
pF1KE5 GPQTESKNEASSRDVVYGPQPQPLENQLLSEETKSTETETGSRVGKLPEASRILNTILSN
:...:.. . . .. ... ::: .: .
NP_150 MAPKLLLLLCLFSGLHARSRKVEEDEYEDSSSNQKWVLAPKSQDTDVTLILNKLLRE
10 20 30 40 50
90 100 110 120 130 140
pF1KE5 YDHKLRPGIGEKPTVVTVEIAVNSLGPLSILDMEYTIDIIFSQTWYDERLCYNDTFESLV
::.:::: :: ::::. :.: :::.::.: ..::: :::.:.::: : :: .:.:.. :.
NP_150 YDKKLRPDIGIKPTVIDVDIYVNSIGPVSSINMEYQIDIFFAQTWTDSRLRFNSTMKILT
60 70 80 90 100 110
150 160 170 180 190 200
pF1KE5 LNGNVVSQLWIPDTFFRNSKRTHEHEITMPNQMVRIYKDGKVLYTIRMTIDAGCSLHMLR
::.:.:. .:::::.::::: .. : :: :::..::..:::.:::.:.::.: :.:..
NP_150 LNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKILYTLRLTINAECQLQLHN
120 130 140 150 160 170
210 220 230 240 250 260
pF1KE5 FPMDSHSCPLSFSSFSYPENEMIYKWENFKLEINEKNSWKLFQFDFTGVSNKTEIITTPV
:::: ::::: :::..::..::::.:.. ..: ...::.:.:::: :. : :::.:: .
NP_150 FPMDEHSCPLIFSSYGYPKEEMIYRWRKNSVEAADQKSWRLYQFDFMGLRNTTEIVTTSA
180 190 200 210 220 230
270 280 290 300 310 320
pF1KE5 GDFMVMTIFFNVSRRFGYVAFQNYVPSSVTTMLSWVSFWIKTESAPARTSLGITSVLTMT
::..::::.:..:::.:: ..:.:.: .:..::::::::: ...::::.::::.:::::
NP_150 GDYVVMTIYFELSRRMGYFTIQTYIPCILTVVLSWVSFWIKKDATPARTALGITTVLTMT
240 250 260 270 280 290
330 340 350 360
pF1KE5 TLGTFSRKNFPRVSYITALDFYIAICFVFCFCALLEFAVLNFLM
::.:..::..:::::.::.:.....::.: : ::.:.:.::.
NP_150 TLSTIARKSLPRVSYVTAMDLFVTVCFLFVFAALMEYATLNYYSSCRKPTTTKKTTSLLH
300 310 320 330 340 350
NP_150 PDSSRWIPERISLQAPSNYSLLDMRPPPTAMITLNNSVYWQEFEDTCVYECLDGKDCQSF
360 370 380 390 400 410
>>XP_011519732 (OMIM: 600233) PREDICTED: gamma-aminobuty (473 aa)
initn: 1232 init1: 1232 opt: 1234 Z-score: 1539.9 bits: 293.9 E(85289): 4.9e-79
Smith-Waterman score: 1234; 54.8% identity (86.2% similar) in 312 aa overlap (52-363:28-339)
30 40 50 60 70 80
pF1KE5 GPQTESKNEASSRDVVYGPQPQPLENQLLSEETKSTETETGSRVGKLPEASRILNTILSN
:...:.. . . .. ... ::: .: .
XP_011 MAPKLLLLLCLFSGLHARSRKVEEDEYEDSSSNQKWVLAPKSQDTDVTLILNKLLRE
10 20 30 40 50
90 100 110 120 130 140
pF1KE5 YDHKLRPGIGEKPTVVTVEIAVNSLGPLSILDMEYTIDIIFSQTWYDERLCYNDTFESLV
::.:::: :: ::::. :.: :::.::.: ..::: :::.:.::: : :: .:.:.. :.
XP_011 YDKKLRPDIGIKPTVIDVDIYVNSIGPVSSINMEYQIDIFFAQTWTDSRLRFNSTMKILT
60 70 80 90 100 110
150 160 170 180 190 200
pF1KE5 LNGNVVSQLWIPDTFFRNSKRTHEHEITMPNQMVRIYKDGKVLYTIRMTIDAGCSLHMLR
::.:.:. .:::::.::::: .. : :: :::..::..:::.:::.:.::.: :.:..
XP_011 LNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKILYTLRLTINAECQLQLHN
120 130 140 150 160 170
210 220 230 240 250 260
pF1KE5 FPMDSHSCPLSFSSFSYPENEMIYKWENFKLEINEKNSWKLFQFDFTGVSNKTEIITTPV
:::: ::::: :::..::..::::.:.. ..: ...::.:.:::: :. : :::.:: .
XP_011 FPMDEHSCPLIFSSYGYPKEEMIYRWRKNSVEAADQKSWRLYQFDFMGLRNTTEIVTTSA
180 190 200 210 220 230
270 280 290 300 310 320
pF1KE5 GDFMVMTIFFNVSRRFGYVAFQNYVPSSVTTMLSWVSFWIKTESAPARTSLGITSVLTMT
::..::::.:..:::.:: ..:.:.: .:..::::::::: ...::::.::::.:::::
XP_011 GDYVVMTIYFELSRRMGYFTIQTYIPCILTVVLSWVSFWIKKDATPARTALGITTVLTMT
240 250 260 270 280 290
330 340 350 360
pF1KE5 TLGTFSRKNFPRVSYITALDFYIAICFVFCFCALLEFAVLNFLM
::.:..::..:::::.::.:.....::.: : ::.:.:.::.
XP_011 TLSTIARKSLPRVSYVTAMDLFVTVCFLFVFAALMEYATLNYYSSCRKPTTTKKTTSLLH
300 310 320 330 340 350
XP_011 PDSSRWIPERISLQAPSVRIALQNYSLLDMRPPPTAMITLNNSVYWQEFEDTCVYECLDG
360 370 380 390 400 410
>>NP_000807 (OMIM: 137164,607681,611277) gamma-aminobuty (467 aa)
initn: 1218 init1: 1218 opt: 1226 Z-score: 1530.0 bits: 292.1 E(85289): 1.8e-78
Smith-Waterman score: 1226; 53.5% identity (88.0% similar) in 301 aa overlap (67-365:60-360)
40 50 60 70 80 90
pF1KE5 VYGPQPQPLENQLLSEETKSTETETGSRVGKLPEA--SRILNTILSNYDHKLRPGIGEKP
:.::. . :::..: .::.:::: :: ::
NP_000 LLSLYPGFTSQKSDDDYEDYASNKTWVLTPKVPEGDVTVILNNLLEGYDNKLRPDIGVKP
30 40 50 60 70 80
100 110 120 130 140 150
pF1KE5 TVVTVEIAVNSLGPLSILDMEYTIDIIFSQTWYDERLCYNDTFESLVLNGNVVSQLWIPD
:.. ... :::.::.. ..:::::::.:.:::::.:: .:.:.. : ::.:.:...::::
NP_000 TLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRRLKFNSTIKVLRLNSNMVGKIWIPD
90 100 110 120 130 140
160 170 180 190 200 210
pF1KE5 TFFRNSKRTHEHEITMPNQMVRIYKDGKVLYTIRMTIDAGCSLHMLRFPMDSHSCPLSFS
:::::::.. : :: ::.:.::..::.::::.:.:::: :.:.. :::: ::::: ::
NP_000 TFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLTIDAECQLQLHNFPMDEHSCPLEFS
150 160 170 180 190 200
220 230 240 250 260 270
pF1KE5 SFSYPENEMIYKWENFKLEINEKNSWKLFQFDFTGVSNKTEIITTPVGDFMVMTIFFNVS
:..::..:..:.:. ..:... ::.:.::.:.:. : ::.. : ::..::...:..:
NP_000 SYGYPREEIVYQWKRSSVEVGDTRSWRLYQFSFVGLRNTTEVVKTTSGDYVVMSVYFDLS
210 220 230 240 250 260
280 290 300 310 320 330
pF1KE5 RRFGYVAFQNYVPSSVTTMLSWVSFWIKTESAPARTSLGITSVLTMTTLGTFSRKNFPRV
::.:: ..:.:.: .. ..::::::::. ...:::::::::.:::::::.:..::..:.:
NP_000 RRMGYFTIQTYIPCTLIVVLSWVSFWINKDAVPARTSLGITTVLTMTTLSTIARKSLPKV
270 280 290 300 310 320
340 350 360
pF1KE5 SYITALDFYIAICFVFCFCALLEFAVLNFLM
::.::.:.....::.: : ::.:...:....
NP_000 SYVTAMDLFVSVCFIFVFSALVEYGTLHYFVSNRKPSKDKDKKKKNPAPTIDIRPRSATI
330 340 350 360 370 380
NP_000 QMNNATHLQERDEEYGYECLDGKDCASFFCCFEDCRTGAWRHGRIHIRIAKMDSYARIFF
390 400 410 420 430 440
>>NP_944494 (OMIM: 137164,607681,611277) gamma-aminobuty (475 aa)
initn: 1218 init1: 1218 opt: 1226 Z-score: 1529.9 bits: 292.1 E(85289): 1.8e-78
Smith-Waterman score: 1226; 53.5% identity (88.0% similar) in 301 aa overlap (67-365:60-360)
40 50 60 70 80 90
pF1KE5 VYGPQPQPLENQLLSEETKSTETETGSRVGKLPEA--SRILNTILSNYDHKLRPGIGEKP
:.::. . :::..: .::.:::: :: ::
NP_944 LLSLYPGFTSQKSDDDYEDYASNKTWVLTPKVPEGDVTVILNNLLEGYDNKLRPDIGVKP
30 40 50 60 70 80
100 110 120 130 140 150
pF1KE5 TVVTVEIAVNSLGPLSILDMEYTIDIIFSQTWYDERLCYNDTFESLVLNGNVVSQLWIPD
:.. ... :::.::.. ..:::::::.:.:::::.:: .:.:.. : ::.:.:...::::
NP_944 TLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRRLKFNSTIKVLRLNSNMVGKIWIPD
90 100 110 120 130 140
160 170 180 190 200 210
pF1KE5 TFFRNSKRTHEHEITMPNQMVRIYKDGKVLYTIRMTIDAGCSLHMLRFPMDSHSCPLSFS
:::::::.. : :: ::.:.::..::.::::.:.:::: :.:.. :::: ::::: ::
NP_944 TFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLTIDAECQLQLHNFPMDEHSCPLEFS
150 160 170 180 190 200
220 230 240 250 260 270
pF1KE5 SFSYPENEMIYKWENFKLEINEKNSWKLFQFDFTGVSNKTEIITTPVGDFMVMTIFFNVS
:..::..:..:.:. ..:... ::.:.::.:.:. : ::.. : ::..::...:..:
NP_944 SYGYPREEIVYQWKRSSVEVGDTRSWRLYQFSFVGLRNTTEVVKTTSGDYVVMSVYFDLS
210 220 230 240 250 260
280 290 300 310 320 330
pF1KE5 RRFGYVAFQNYVPSSVTTMLSWVSFWIKTESAPARTSLGITSVLTMTTLGTFSRKNFPRV
::.:: ..:.:.: .. ..::::::::. ...:::::::::.:::::::.:..::..:.:
NP_944 RRMGYFTIQTYIPCTLIVVLSWVSFWINKDAVPARTSLGITTVLTMTTLSTIARKSLPKV
270 280 290 300 310 320
340 350 360
pF1KE5 SYITALDFYIAICFVFCFCALLEFAVLNFLM
::.::.:.....::.: : ::.:...:....
NP_944 SYVTAMDLFVSVCFIFVFSALVEYGTLHYFVSNRKPSKDKDKKKKNPLLRMFSFKAPTID
330 340 350 360 370 380
NP_944 IRPRSATIQMNNATHLQERDEEYGYECLDGKDCASFFCCFEDCRTGAWRHGRIHIRIAKM
390 400 410 420 430 440
>>NP_775807 (OMIM: 137166) gamma-aminobutyric acid recep (465 aa)
initn: 1234 init1: 1211 opt: 1215 Z-score: 1516.3 bits: 289.5 E(85289): 1e-77
Smith-Waterman score: 1215; 54.2% identity (87.8% similar) in 295 aa overlap (70-364:63-357)
40 50 60 70 80 90
pF1KE5 PQPQPLENQLLSEETKSTETETGSRVGKLPEASRILNTILSNYDHKLRPGIGEKPTVVTV
. ..:::..:..::.:::: :: .:::. .
NP_775 GNCVDKADDEDDEDLTVNKTWVLAPKIHEGDITQILNSLLQGYDNKLRPDIGVRPTVIET
40 50 60 70 80 90
100 110 120 130 140 150
pF1KE5 EIAVNSLGPLSILDMEYTIDIIFSQTWYDERLCYNDTFESLVLNGNVVSQLWIPDTFFRN
.. :::.::.. ..:::::::::.:::.: :: .:.:.. :.::.:.:...:::::::::
NP_775 DVYVNSIGPVDPINMEYTIDIIFAQTWFDSRLKFNSTMKVLMLNSNMVGKIWIPDTFFRN
100 110 120 130 140 150
160 170 180 190 200 210
pF1KE5 SKRTHEHEITMPNQMVRIYKDGKVLYTIRMTIDAGCSLHMLRFPMDSHSCPLSFSSFSYP
:... : :: ::...::..::.::::.:.::.: : :.. :::: ::::: :::..::
NP_775 SRKSDAHWITTPNRLLRIWNDGRVLYTLRLTINAECYLQLHNFPMDEHSCPLEFSSYGYP
160 170 180 190 200 210
220 230 240 250 260 270
pF1KE5 ENEMIYKWENFKLEINEKNSWKLFQFDFTGVSNKTEIITTPVGDFMVMTIFFNVSRRFGY
.::. :::.. ..:. . . :.:.:: :.:. :.::: : ::...:::::..:::.::
NP_775 KNEIEYKWKKPSVEVADPKYWRLYQFAFVGLRNSTEITHTISGDYVIMTIFFDLSRRMGY
220 230 240 250 260 270
280 290 300 310 320 330
pF1KE5 VAFQNYVPSSVTTMLSWVSFWIKTESAPARTSLGITSVLTMTTLGTFSRKNFPRVSYITA
..:.:.: .:..::::::::. ...:::::::::.:::::::.:..::..:.:::.::
NP_775 FTIQTYIPCILTVVLSWVSFWINKDAVPARTSLGITTVLTMTTLSTIARKSLPKVSYVTA
280 290 300 310 320 330
340 350 360
pF1KE5 LDFYIAICFVFCFCALLEFAVLNFLM
.:.....::.: : ::.:...:...
NP_775 MDLFVSVCFIFVFAALMEYGTLHYFTSNQKGKTATKDRKLKNKASMTPGLHPGSTLIPMN
340 350 360 370 380 390
>>NP_000802 (OMIM: 137143) gamma-aminobutyric acid recep (453 aa)
initn: 958 init1: 597 opt: 1029 Z-score: 1284.4 bits: 246.6 E(85289): 8.4e-65
Smith-Waterman score: 1029; 48.0% identity (82.8% similar) in 296 aa overlap (72-364:33-327)
50 60 70 80 90 100
pF1KE5 PQPLENQLLSEETKSTETETGSRVGKLPEASRILNTILSNYDHKLRPGIGEKPTVVTVEI
::::...: .::..::::.: : : ..:
NP_000 SSLPWLCIILWLENALGKLEVEGNFYSENVSRILDNLLEGYDNRLRPGFGGAVTEVKTDI
10 20 30 40 50 60
110 120 130 140 150 160
pF1KE5 AVNSLGPLSILDMEYTIDIIFSQTWYDERLCYNDTFESLVLNGNVVSQLWIPDTFFRNSK
:.:.::.: ..::::.:..: ::: :::: .. : : ::. .::..: :::::::.:
NP_000 YVTSFGPVSDVEMEYTMDVFFRQTWTDERLKFGGPTEILSLNNLMVSKIWTPDTFFRNGK
70 80 90 100 110 120
170 180 190 200 210 220
pF1KE5 RTHEHEITMPNQMVRIYKDGKVLYTIRMTIDAGCSLHMLRFPMDSHSCPLSFSSFSYPEN
.. :..: ::.. ::...: .:::.:.::.: : .... ::::.:.:::.:.:..::..
NP_000 KSIAHNMTTPNKLFRIMQNGTILYTMRLTINADCPMRLVNFPMDGHACPLKFGSYAYPKS
130 140 150 160 170 180
230 240 250 260 270
pF1KE5 EMIYKWEN---FKLEINEKNSWKLFQFDFTGVSNKTEIITTPVGDFMVMTIFFNVSRRFG
:.:: :.. ...:. :..: .:.:.:. : . ..: : . .:....::..:...:..:
NP_000 EIIYTWKKGPLYSVEVPEESS-SLLQYDLIGQTVSSETIKSNTGEYVIMTVYFHLQRKMG
190 200 210 220 230 240
280 290 300 310 320 330
pF1KE5 YVAFQNYVPSSVTTMLSWVSFWIKTESAPARTSLGITSVLTMTTLGTFSRKNFPRVSYIT
: .: :.: .:..:: :::::. ::.:::: .:::.:::::::. .:...:.::: :
NP_000 YFMIQIYTPCIMTVILSQVSFWINKESVPARTVFGITTVLTMTTLSISARHSLPKVSYAT
250 260 270 280 290 300
340 350 360
pF1KE5 ALDFYIAICFVFCFCALLEFAVLNFLM
:.:..::.::.: : ::.:::..:..
NP_000 AMDWFIAVCFAFVFSALIEFAAVNYFTNLQTQKAKRKAQFAAPPTVTISKATEPLEAEIV
310 320 330 340 350 360
365 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 01:37:00 2016 done: Tue Nov 8 01:37:01 2016
Total Scan time: 5.800 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]