Result of FASTA (omim) for
pFN21AE5521
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5521, 437 aa
1>>>pF1KE5521 437 - 437 aa - 437 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.7917+/-0.000418; mu= 14.4796+/- 0.026
mean_var=63.2717+/-12.669, 0's: 0 Z-trim(110.4): 38 B-trim: 25 in 1/54
Lambda= 0.161239
statistics sampled from 18704 (18742) to 18704 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.586), E-opt: 0.2 (0.22), width: 16
Scan time: 6.980
The best scores are: opt bits E(85289)
NP_065094 (OMIM: 609562,614417,614418) carboxypept ( 437) 3022 712.0 7.7e-205
XP_016869135 (OMIM: 609562,614417,614418) PREDICTE ( 289) 2038 483.0 4.2e-136
XP_011515872 (OMIM: 609562,614417,614418) PREDICTE ( 289) 2038 483.0 4.2e-136
XP_016869136 (OMIM: 609562,614417,614418) PREDICTE ( 247) 1444 344.8 1.4e-94
NP_001862 (OMIM: 114852) carboxypeptidase B prepro ( 417) 1223 293.5 7e-79
NP_001861 (OMIM: 114851) mast cell carboxypeptidas ( 417) 1185 284.7 3.2e-76
NP_001863 (OMIM: 603101) carboxypeptidase B2 isofo ( 423) 1082 260.7 5.3e-69
NP_001860 (OMIM: 600688) carboxypeptidase A2 precu ( 419) 1077 259.5 1.2e-68
XP_016875882 (OMIM: 603101) PREDICTED: carboxypept ( 414) 1076 259.3 1.4e-68
NP_057436 (OMIM: 607635) carboxypeptidase A4 isofo ( 421) 1052 253.7 6.6e-67
NP_775100 (OMIM: 609563) carboxypeptidase O precur ( 374) 1018 245.8 1.4e-64
XP_016858861 (OMIM: 609563) PREDICTED: carboxypept ( 374) 1018 245.8 1.4e-64
NP_001859 (OMIM: 114850) carboxypeptidase A1 prepr ( 419) 994 240.2 7.6e-63
XP_011515005 (OMIM: 609561) PREDICTED: carboxypept ( 436) 994 240.2 7.9e-63
XP_011515004 (OMIM: 609561) PREDICTED: carboxypept ( 436) 994 240.2 7.9e-63
XP_005250769 (OMIM: 609561) PREDICTED: carboxypept ( 436) 994 240.2 7.9e-63
NP_525124 (OMIM: 609561) carboxypeptidase A5 isofo ( 436) 994 240.2 7.9e-63
NP_001305152 (OMIM: 609561) carboxypeptidase A5 is ( 436) 994 240.2 7.9e-63
XP_005250767 (OMIM: 609561) PREDICTED: carboxypept ( 436) 994 240.2 7.9e-63
NP_001120913 (OMIM: 609561) carboxypeptidase A5 is ( 436) 994 240.2 7.9e-63
XP_011515000 (OMIM: 609561) PREDICTED: carboxypept ( 436) 994 240.2 7.9e-63
XP_011515003 (OMIM: 609561) PREDICTED: carboxypept ( 436) 994 240.2 7.9e-63
NP_001156918 (OMIM: 607635) carboxypeptidase A4 is ( 388) 868 210.9 4.7e-54
NP_001120914 (OMIM: 609561) carboxypeptidase A5 is ( 403) 694 170.4 7.4e-42
XP_011515006 (OMIM: 609561) PREDICTED: carboxypept ( 403) 694 170.4 7.4e-42
NP_001265470 (OMIM: 603101) carboxypeptidase B2 is ( 386) 618 152.7 1.5e-36
XP_011515007 (OMIM: 609561) PREDICTED: carboxypept ( 308) 490 123.0 1.1e-27
NP_001865 (OMIM: 114860) carboxypeptidase M precur ( 443) 184 51.8 4.2e-06
NP_001005502 (OMIM: 114860) carboxypeptidase M pre ( 443) 184 51.8 4.2e-06
NP_938079 (OMIM: 114860) carboxypeptidase M precur ( 443) 184 51.8 4.2e-06
NP_001299 (OMIM: 212070,603103) carboxypeptidase N ( 458) 164 47.2 0.00011
NP_001864 (OMIM: 114855) carboxypeptidase E prepro ( 476) 148 43.4 0.0015
NP_001186704 (OMIM: 603102) carboxypeptidase D iso (1133) 153 44.7 0.0015
NP_001295 (OMIM: 603102) carboxypeptidase D isofor (1380) 153 44.7 0.0018
NP_001014448 (OMIM: 603105) carboxypeptidase Z iso ( 515) 143 42.3 0.0036
NP_003643 (OMIM: 603105) carboxypeptidase Z isofor ( 641) 143 42.3 0.0044
NP_001014447 (OMIM: 603105) carboxypeptidase Z iso ( 652) 143 42.3 0.0045
NP_001171628 (OMIM: 609555) probable carboxypeptid ( 660) 143 42.3 0.0045
>>NP_065094 (OMIM: 609562,614417,614418) carboxypeptidas (437 aa)
initn: 3022 init1: 3022 opt: 3022 Z-score: 3798.5 bits: 712.0 E(85289): 7.7e-205
Smith-Waterman score: 3022; 99.8% identity (99.8% similar) in 437 aa overlap (1-437:1-437)
10 20 30 40 50 60
pF1KE5 MKCLGKRRGQAAAFLPLCWLFLKILQPGHSHLYNNRYAGDKVIRFIPKTEEEAYALKKIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 MKCLGKRRGQAAAFLPLCWLFLKILQPGHSHLYNNRYAGDKVIRFIPKTEEEAYALKKIS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 YQLKVDLWQPSSISYVSEGTVTDVHIPQNGSRALLAFLQEANIQYKVLIEDLQKTLEKGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 YQLKVDLWQPSSISYVSEGTVTDVHIPQNGSRALLAFLQEANIQYKVLIEDLQKTLEKGS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 SLHTQRNRRSLSGYNYEVYHSLEEIQNWMHHLNKTHSGLIHMFSIGRSYEGRCLFILKLG
:::::::::::::::::::::::::::::::::::::::::::::::::::: :::::::
NP_065 SLHTQRNRRSLSGYNYEVYHSLEEIQNWMHHLNKTHSGLIHMFSIGRSYEGRSLFILKLG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 RRSRLKRAVWIDCGIHAREWIGPAFCQWFVKEALLTYKSDPAMRKMLNHLYFYIMPVFNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 RRSRLKRAVWIDCGIHAREWIGPAFCQWFVKEALLTYKSDPAMRKMLNHLYFYIMPVFNV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 DGYHFSWTNDRFWRKTRSRNSRFRCRGVDANRNWKVKWCDEGASMHPCDDTYCGPFPESE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 DGYHFSWTNDRFWRKTRSRNSRFRCRGVDANRNWKVKWCDEGASMHPCDDTYCGPFPESE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE5 PEVKAVANFLRKHRKHIRAYLSFHAYAQMLLYPYSYKYATIPNFRCVESAAYKAVNALQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 PEVKAVANFLRKHRKHIRAYLSFHAYAQMLLYPYSYKYATIPNFRCVESAAYKAVNALQS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE5 VYGVRYRYGPASTTLYVSSGSSMDWAYKNGIPYAFAFELRDTGYFGFLLPEMLIKPTCTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 VYGVRYRYGPASTTLYVSSGSSMDWAYKNGIPYAFAFELRDTGYFGFLLPEMLIKPTCTE
370 380 390 400 410 420
430
pF1KE5 TMLAVKNITMHLLKKCP
:::::::::::::::::
NP_065 TMLAVKNITMHLLKKCP
430
>>XP_016869135 (OMIM: 609562,614417,614418) PREDICTED: c (289 aa)
initn: 2038 init1: 2038 opt: 2038 Z-score: 2564.5 bits: 483.0 E(85289): 4.2e-136
Smith-Waterman score: 2038; 99.7% identity (99.7% similar) in 289 aa overlap (149-437:1-289)
120 130 140 150 160 170
pF1KE5 GSSLHTQRNRRSLSGYNYEVYHSLEEIQNWMHHLNKTHSGLIHMFSIGRSYEGRCLFILK
:::::::::::::::::::::::: :::::
XP_016 MHHLNKTHSGLIHMFSIGRSYEGRSLFILK
10 20 30
180 190 200 210 220 230
pF1KE5 LGRRSRLKRAVWIDCGIHAREWIGPAFCQWFVKEALLTYKSDPAMRKMLNHLYFYIMPVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGRRSRLKRAVWIDCGIHAREWIGPAFCQWFVKEALLTYKSDPAMRKMLNHLYFYIMPVF
40 50 60 70 80 90
240 250 260 270 280 290
pF1KE5 NVDGYHFSWTNDRFWRKTRSRNSRFRCRGVDANRNWKVKWCDEGASMHPCDDTYCGPFPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NVDGYHFSWTNDRFWRKTRSRNSRFRCRGVDANRNWKVKWCDEGASMHPCDDTYCGPFPE
100 110 120 130 140 150
300 310 320 330 340 350
pF1KE5 SEPEVKAVANFLRKHRKHIRAYLSFHAYAQMLLYPYSYKYATIPNFRCVESAAYKAVNAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SEPEVKAVANFLRKHRKHIRAYLSFHAYAQMLLYPYSYKYATIPNFRCVESAAYKAVNAL
160 170 180 190 200 210
360 370 380 390 400 410
pF1KE5 QSVYGVRYRYGPASTTLYVSSGSSMDWAYKNGIPYAFAFELRDTGYFGFLLPEMLIKPTC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QSVYGVRYRYGPASTTLYVSSGSSMDWAYKNGIPYAFAFELRDTGYFGFLLPEMLIKPTC
220 230 240 250 260 270
420 430
pF1KE5 TETMLAVKNITMHLLKKCP
:::::::::::::::::::
XP_016 TETMLAVKNITMHLLKKCP
280
>>XP_011515872 (OMIM: 609562,614417,614418) PREDICTED: c (289 aa)
initn: 2038 init1: 2038 opt: 2038 Z-score: 2564.5 bits: 483.0 E(85289): 4.2e-136
Smith-Waterman score: 2038; 99.7% identity (99.7% similar) in 289 aa overlap (149-437:1-289)
120 130 140 150 160 170
pF1KE5 GSSLHTQRNRRSLSGYNYEVYHSLEEIQNWMHHLNKTHSGLIHMFSIGRSYEGRCLFILK
:::::::::::::::::::::::: :::::
XP_011 MHHLNKTHSGLIHMFSIGRSYEGRSLFILK
10 20 30
180 190 200 210 220 230
pF1KE5 LGRRSRLKRAVWIDCGIHAREWIGPAFCQWFVKEALLTYKSDPAMRKMLNHLYFYIMPVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LGRRSRLKRAVWIDCGIHAREWIGPAFCQWFVKEALLTYKSDPAMRKMLNHLYFYIMPVF
40 50 60 70 80 90
240 250 260 270 280 290
pF1KE5 NVDGYHFSWTNDRFWRKTRSRNSRFRCRGVDANRNWKVKWCDEGASMHPCDDTYCGPFPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NVDGYHFSWTNDRFWRKTRSRNSRFRCRGVDANRNWKVKWCDEGASMHPCDDTYCGPFPE
100 110 120 130 140 150
300 310 320 330 340 350
pF1KE5 SEPEVKAVANFLRKHRKHIRAYLSFHAYAQMLLYPYSYKYATIPNFRCVESAAYKAVNAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SEPEVKAVANFLRKHRKHIRAYLSFHAYAQMLLYPYSYKYATIPNFRCVESAAYKAVNAL
160 170 180 190 200 210
360 370 380 390 400 410
pF1KE5 QSVYGVRYRYGPASTTLYVSSGSSMDWAYKNGIPYAFAFELRDTGYFGFLLPEMLIKPTC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QSVYGVRYRYGPASTTLYVSSGSSMDWAYKNGIPYAFAFELRDTGYFGFLLPEMLIKPTC
220 230 240 250 260 270
420 430
pF1KE5 TETMLAVKNITMHLLKKCP
:::::::::::::::::::
XP_011 TETMLAVKNITMHLLKKCP
280
>>XP_016869136 (OMIM: 609562,614417,614418) PREDICTED: c (247 aa)
initn: 1444 init1: 1444 opt: 1444 Z-score: 1818.9 bits: 344.8 E(85289): 1.4e-94
Smith-Waterman score: 1444; 99.1% identity (99.5% similar) in 214 aa overlap (1-214:1-214)
10 20 30 40 50 60
pF1KE5 MKCLGKRRGQAAAFLPLCWLFLKILQPGHSHLYNNRYAGDKVIRFIPKTEEEAYALKKIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MKCLGKRRGQAAAFLPLCWLFLKILQPGHSHLYNNRYAGDKVIRFIPKTEEEAYALKKIS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 YQLKVDLWQPSSISYVSEGTVTDVHIPQNGSRALLAFLQEANIQYKVLIEDLQKTLEKGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YQLKVDLWQPSSISYVSEGTVTDVHIPQNGSRALLAFLQEANIQYKVLIEDLQKTLEKGS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 SLHTQRNRRSLSGYNYEVYHSLEEIQNWMHHLNKTHSGLIHMFSIGRSYEGRCLFILKLG
:::::::::::::::::::::::::::::::::::::::::::::::::::: :::::::
XP_016 SLHTQRNRRSLSGYNYEVYHSLEEIQNWMHHLNKTHSGLIHMFSIGRSYEGRSLFILKLG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 RRSRLKRAVWIDCGIHAREWIGPAFCQWFVKEALLTYKSDPAMRKMLNHLYFYIMPVFNV
::::::::::::::::::::::::::::::::.:
XP_016 RRSRLKRAVWIDCGIHAREWIGPAFCQWFVKEVLENTAHKCQECTKFTKYLCHYQNHKSM
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 DGYHFSWTNDRFWRKTRSRNSRFRCRGVDANRNWKVKWCDEGASMHPCDDTYCGPFPESE
XP_016 LNLVSIE
>>NP_001862 (OMIM: 114852) carboxypeptidase B preproprot (417 aa)
initn: 1127 init1: 1078 opt: 1223 Z-score: 1537.2 bits: 293.5 E(85289): 7e-79
Smith-Waterman score: 1223; 41.1% identity (73.7% similar) in 418 aa overlap (17-434:2-414)
10 20 30 40 50 60
pF1KE5 MKCLGKRRGQAAAFLPLCWLFLKILQPGHSHLYNNRYAGDKVIRFIPKTEEEAYALKKIS
: : : . . .: .... :.::.: . :.. .....
NP_001 MLALLVLVTVALASAHHGGEHFEGEKVFRVNVEDENHINIIRELA
10 20 30 40
70 80 90 100 110 120
pF1KE5 YQLKVDLWQPSSISYVSEGTVTDVHIPQNGSRALLAFLQEANIQYKVLIEDLQKTLEKGS
..:.:.:.:.. .. ...: .. . . .. :.. ..:::::: .:....:
NP_001 STTQIDFWKPDSVTQIKPHSTVDFRVKAEDTVTVENVLKQNELQYKVLISNLRNVVE---
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE5 SLHTQRNRRSLSGYNYEVYHSLEEIQNWMHHLNKTHSGLIHMFSIGRSYEGRCLFILKLG
. .: : .:..:: :.. : :. : ... . .:: :: ..::: ...::.:
NP_001 AQFDSRVRA--TGHSYEKYNKWETIEAWTQQVATENPALISRSVIGTTFEGRAIYLLKVG
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE5 RRSRLKRAVWIDCGIHAREWIGPAFCQWFVKEALLTYKSDPAMRKMLNHLYFYIMPVFNV
. .. : :...:::.::::::.::::::::.::. :: . . ..:..: ::..::.:.
NP_001 KAGQNKPAIFMDCGFHAREWISPAFCQWFVREAVRTYGREIQVTELLDKLDFYVLPVLNI
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE5 DGYHFSWTNDRFWRKTRSRNSRFRCRGVDANRNWKVKWCDEGASMHPCDDTYCGPFPESE
::: ..::..:::::::: .. : :.: :::. . ::. ::: .:::.::::: :::
NP_001 DGYIYTWTKSRFWRKTRSTHTGSSCIGTDPNRNFDAGWCEIGASRNPCDETYCGPAAESE
230 240 250 260 270 280
310 320 330 340 350 360
pF1KE5 PEVKAVANFLRKHRKHIRAYLSFHAYAQMLLYPYSYKYATIPNFRCVESAAYKAVNALQS
:.::.:.:.:.. . :.:::..:.:.::..::::: : : ... : .:. : :
NP_001 KETKALADFIRNKLSSIKAYLTIHSYSQMMIYPYSYAYKLGENNAELNALAKATVKELAS
290 300 310 320 330 340
370 380 390 400 410 420
pF1KE5 VYGVRYRYGPASTTLYVSSGSSMDWAYKNGIPYAFAFELRDTGYFGFLLPEMLIKPTCTE
..:..: :::..::.: ..:.: :::: .:: :.:.::::::: .:::::: :. :: :
NP_001 LHGTKYTYGPGATTIYPAAGGSDDWAYDQGIRYSFTFELRDTGRYGFLLPESQIRATCEE
350 360 370 380 390 400
430
pF1KE5 TMLAVKNITMHLLKKCP
:.::.: .. ..:.
NP_001 TFLAIKYVASYVLEHLY
410
>>NP_001861 (OMIM: 114851) mast cell carboxypeptidase A (417 aa)
initn: 1115 init1: 1004 opt: 1185 Z-score: 1489.4 bits: 284.7 E(85289): 3.2e-76
Smith-Waterman score: 1185; 42.5% identity (73.8% similar) in 400 aa overlap (36-434:20-414)
10 20 30 40 50 60
pF1KE5 KRRGQAAAFLPLCWLFLKILQPGHSHLYNNRYAGDKVIRFIPKTEEEAYALKKISYQLKV
:. .::.: :. :..: .: .. ..
NP_001 MRLILPVGLIATTLAIAPVRFDREKVFRVKPQDEKQADIIKDLAKTNEL
10 20 30 40
70 80 90 100 110 120
pF1KE5 DLWQPSSISYVSEGTVTDVHIPQNGSRALLAFLQEANIQYKVLIEDLQKTLEKGSSLHTQ
:.: :.. .:. . ..: .. .. :.:. . :.. ...:..::.:::. .:: ..
NP_001 DFWYPGATHHVAANMMVDFRVSEKESQAIQSALDQNKMHYEILIHDLQEEIEKQFDV---
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE5 RNRRSLSG-YNYEVYHSLEEIQNWMHHLNKTHSGLIHMFSIGRSYEGRCLFILKLGRRSR
.... : ..: :.. :.: : ... . .. ..:: . : :..::.:....
NP_001 --KEDIPGRHSYAKYNNWEKIVAWTEKMMDKYPEMVSRIKIGSTVEDNPLYVLKIGEKNE
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE5 LKRAVWIDCGIHAREWIGPAFCQWFVKEALLTYKSDPAMRKMLNHLYFYIMPVFNVDGYH
..:.. :::::::::..:::::::: .: :: . : :.:... :::.::::::::
NP_001 RRKAIFTDCGIHAREWVSPAFCQWFVYQATKTYGRNKIMTKLLDRMNFYILPVFNVDGYI
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE5 FSWTNDRFWRKTRSRNSRFRCRGVDANRNWKVKWCDEGASMHPCDDTYCGPFPESEPEVK
.:::..:.:::.::.:. .: :.: :::....: . . :: :.: : :::: :.:
NP_001 WSWTKNRMWRKNRSKNQNSKCIGTDLNRNFNASWNSIPNTNDPCADNYRGSAPESEKETK
230 240 250 260 270 280
310 320 330 340 350 360
pF1KE5 AVANFLRKHRKHIRAYLSFHAYAQMLLYPYSYKYATIPNFRCVESAAYKAVNALQSVYGV
::.::.:.: ..:..:..::.:.::::.::.: :: . . ..: ....:.. : .
NP_001 AVTNFIRSHLNEIKVYITFHSYSQMLLFPYGYTSKLPPNHEDLAKVAKIGTDVLSTRYET
290 300 310 320 330 340
370 380 390 400 410 420
pF1KE5 RYRYGPASTTLYVSSGSSMDWAYKNGIPYAFAFELRDTGYFGFLLPEMLIKPTCTETMLA
:: ::: .:.: ::::.:::: :: ..::::::: : ::::::: ::::: :::::
NP_001 RYIYGPIESTIYPISGSSLDWAYDLGIKHTFAFELRDKGKFGFLLPESRIKPTCRETMLA
350 360 370 380 390 400
430
pF1KE5 VKNITMHLLKKCP
:: :. ..::
NP_001 VKFIAKYILKHTS
410
>>NP_001863 (OMIM: 603101) carboxypeptidase B2 isoform 1 (423 aa)
initn: 1034 init1: 360 opt: 1082 Z-score: 1359.8 bits: 260.7 E(85289): 5.3e-69
Smith-Waterman score: 1082; 40.0% identity (69.3% similar) in 427 aa overlap (15-434:1-421)
10 20 30 40 50
pF1KE5 MKCLGKRRGQAAAFLPLCWL--FLKILQPGHSHLYNNRYAGDKVIRFIPKTEEEAYALKK
. :: : .. :. ..:.. . . .:. .:.: ... .:..
NP_001 MKLCSLAVLVPIVLFCEQHVFA--FQSGQVLAALPRTSRQVQVLQN
10 20 30 40
60 70 80 90 100 110
pF1KE5 ISYQLKVDLWQPSSISYVSEGTVTDVHIPQNGSRA--LLAFLQEANIQYKVLIEDLQKTL
.. .. :::: . . . . .::. :.: . . : :. ..: .::. :.. .
NP_001 LTTTYEIVLWQPVTADLIVKKK--QVHFFVNASDVDNVKAHLNVSGIPCSVLLADVEDLI
50 60 70 80 90 100
120 130 140 150 160 170
pF1KE5 EKGSSLHTQRNRRSLSGYNYEVYHSLEEIQNWMHHLNKTHSGLIHMFSIGRSYEGRCLFI
.. : : : : : : :: ::::.:: .:.. ... : .. . :: :.: :..
NP_001 QQQISNDTVSPRASAS-Y-YEQYHSLNEIYSWIEFITERHPDMLTKIHIGSSFEKYPLYV
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE5 LKL-GRRSRLKRAVWIDCGIHAREWIGPAFCQWFVKEALLTYKSDPAMRKMLNHLYFYIM
::. :... : :.::::::::::::.:::: ::. . : . ..: . ::.:
NP_001 LKVSGKEQAAKNAIWIDCGIHAREWISPAFCLWFIGHITQFYGIIGQYTNLLRLVDFYVM
170 180 190 200 210 220
240 250 260 270 280 290
pF1KE5 PVFNVDGYHFSWTNDRFWRKTRSRNSRFRCRGVDANRNWKVK-WCDEGASMHPCDDTYCG
:: ::::: .:: ..:.:::.:: . .: :.: :::. : ::.:::: :..::::
NP_001 PVVNVDGYDYSWKKNRMWRKNRSFYANNHCIGTDLNRNFASKHWCEEGASSSSCSETYCG
230 240 250 260 270 280
300 310 320 330 340 350
pF1KE5 PFPESEPEVKAVANFLRKHRKHIRAYLSFHAYAQMLLYPYSYKYATIPNFRCVESAAYKA
.:::::::::::.:::.. ..:.::.:.:.:.: ...:::: . . . . .: .:
NP_001 LYPESEPEVKAVASFLRRNINQIKAYISMHSYSQHIVFPYSYTRSKSKDHEELSLVASEA
290 300 310 320 330 340
360 370 380 390 400 410
pF1KE5 VNALQSVY-GVRYRYGPASTTLYVSSGSSMDWAYKNGIPYAFAFELRDTGYFGFLLPEML
: :.... ..:: .: .: :::.. :.. :: : :: :.:..:::::: .::::::
NP_001 VRAIEKISKNTRYTHGHGSETLYLAPGGGDDWIYDLGIKYSFTIELRDTGTYGFLLPERY
350 360 370 380 390 400
420 430
pF1KE5 IKPTCTETMLAVKNITMHLLKKCP
::::: :.. ::..:. :...
NP_001 IKPTCREAFAAVSKIAWHVIRNV
410 420
>>NP_001860 (OMIM: 600688) carboxypeptidase A2 precursor (419 aa)
initn: 894 init1: 437 opt: 1077 Z-score: 1353.6 bits: 259.5 E(85289): 1.2e-68
Smith-Waterman score: 1077; 40.1% identity (70.7% similar) in 406 aa overlap (31-432:15-414)
10 20 30 40 50
pF1KE5 MKCLGKRRGQAAAFLPLCWLFLKILQPGHSHLYN-NRYAGDKVIRFIPKTEEEAYALKKI
:.: . ..::.:....:..::. : ..
NP_001 MAMRLILFFGALFGHIYCLETFVGDQVLEIVPSNEEQIKNLLQL
10 20 30 40
60 70 80 90 100 110
pF1KE5 SYQ--LKVDLWQPSSISYVSEGTVTDVHIPQNGSRALLAFLQEANIQYKVLIEDLQKTLE
: :..:.:. : .. : .. :..: . .:. .::. .: :...:::.: :.
NP_001 EAQEHLQLDFWK----SPTTPGETAHVRVPFVNVQAVKVFLESQGIAYSIMIEDVQVLLD
50 60 70 80 90 100
120 130 140 150 160 170
pF1KE5 KGSSLHTQRNRRSLSG-YNYEVYHSLEEIQNWMHHLNKTHSGLIHMFSIGRSYEGRCLFI
: . :: :: .:. .::.::::.. : .: : ::. .:: :.:.: . .
NP_001 KENEEMLFNRRRERSGNFNFGAYHTLEEISQEMDNLVAEHPGLVSKVNIGSSFENRPMNV
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE5 LKLGRRSRLKRAVWIDCGIHAREWIGPAFCQWFVKEALLTYKSDPAMRKMLNHLYFYIMP
::.. . : :.:.: :::::::. : : ... . : .::.. ..:. : ....:
NP_001 LKFSTGGD-KPAIWLDAGIHAREWVTQATALWTANKIVSDYGKDPSITSILDALDIFLLP
170 180 190 200 210
240 250 260 270 280 290
pF1KE5 VFNVDGYHFSWTNDRFWRKTRSRNSRFRCRGVDANRNWKVKWCDEGASMHPCDDTYCGPF
: : ::: :: :..:.::::::. : : ::: :::: . . ::: .::.:.: ::
NP_001 VTNPDGYVFSQTKNRMWRKTRSKVSGSLCVGVDPNRNWDAGFGGPGASSNPCSDSYHGPS
220 230 240 250 260 270
300 310 320 330 340 350
pF1KE5 PESEPEVKAVANFLRKHRKHIRAYLSFHAYAQMLLYPYSYKYATIPNFRCVESAAYKAVN
.:: :::....:...: : ..:....:.:.:.:..::.:: . . .: . .: ::..
NP_001 ANSEVEVKSIVDFIKSHGK-VKAFITLHSYSQLLMFPYGYKCTKLDDFDELSEVAQKAAQ
280 290 300 310 320 330
360 370 380 390 400 410
pF1KE5 ALQSVYGVRYRYGPASTTLYVSSGSSMDWAYKNGIPYAFAFELRDTGYFGFLLPEMLIKP
.:.:..:..:. :: ...: .::.:.::.: :: :.::::::::: .::::: : :
NP_001 SLRSLHGTKYKVGPICSVIYQASGGSIDWSYDYGIKYSFAFELRDTGRYGFLLPARQILP
340 350 360 370 380 390
420 430
pF1KE5 TCTETMLAVKNITMHLLKKCP
: :: :..: : :.
NP_001 TAEETWLGLKAIMEHVRDHPY
400 410
>>XP_016875882 (OMIM: 603101) PREDICTED: carboxypeptidas (414 aa)
initn: 1034 init1: 360 opt: 1076 Z-score: 1352.5 bits: 259.3 E(85289): 1.4e-68
Smith-Waterman score: 1076; 41.5% identity (70.1% similar) in 402 aa overlap (38-434:15-412)
10 20 30 40 50 60
pF1KE5 RGQAAAFLPLCWLFLKILQPGHSHLYNNRYAGDKVIRFIPKTEEEAYALKKISYQLKVDL
: .:. .:.: ... .:.... .. :
XP_016 MASPVPVESLEAGLACGQVLAALPRTSRQVQVLQNLTTTYEIVL
10 20 30 40
70 80 90 100 110 120
pF1KE5 WQPSSISYVSEGTVTDVHIPQNGSRA--LLAFLQEANIQYKVLIEDLQKTLEKGSSLHTQ
::: . . . . .::. :.: . . : :. ..: .::. :.. ... : :
XP_016 WQPVTADLIVKKK--QVHFFVNASDVDNVKAHLNVSGIPCSVLLADVEDLIQQQISNDTV
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE5 RNRRSLSGYNYEVYHSLEEIQNWMHHLNKTHSGLIHMFSIGRSYEGRCLFILKL-GRRSR
: : : : :: ::::.:: .:.. ... : .. . :: :.: :..::. :...
XP_016 SPRASAS-Y-YEQYHSLNEIYSWIEFITERHPDMLTKIHIGSSFEKYPLYVLKVSGKEQA
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE5 LKRAVWIDCGIHAREWIGPAFCQWFVKEALLTYKSDPAMRKMLNHLYFYIMPVFNVDGYH
: :.::::::::::::.:::: ::. . : . ..: . ::.::: :::::
XP_016 AKNAIWIDCGIHAREWISPAFCLWFIGHITQFYGIIGQYTNLLRLVDFYVMPVVNVDGYD
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE5 FSWTNDRFWRKTRSRNSRFRCRGVDANRNWKVK-WCDEGASMHPCDDTYCGPFPESEPEV
.:: ..:.:::.:: . .: :.: :::. : ::.:::: :..:::: .:::::::
XP_016 YSWKKNRMWRKNRSFYANNHCIGTDLNRNFASKHWCEEGASSSSCSETYCGLYPESEPEV
230 240 250 260 270 280
310 320 330 340 350 360
pF1KE5 KAVANFLRKHRKHIRAYLSFHAYAQMLLYPYSYKYATIPNFRCVESAAYKAVNALQSVY-
::::.:::.. ..:.::.:.:.:.: ...:::: . . . . .: .:: :....
XP_016 KAVASFLRRNINQIKAYISMHSYSQHIVFPYSYTRSKSKDHEELSLVASEAVRAIEKISK
290 300 310 320 330 340
370 380 390 400 410 420
pF1KE5 GVRYRYGPASTTLYVSSGSSMDWAYKNGIPYAFAFELRDTGYFGFLLPEMLIKPTCTETM
..:: .: .: :::.. :.. :: : :: :.:..:::::: .:::::: ::::: :..
XP_016 NTRYTHGHGSETLYLAPGGGDDWIYDLGIKYSFTIELRDTGTYGFLLPERYIKPTCREAF
350 360 370 380 390 400
430
pF1KE5 LAVKNITMHLLKKCP
::..:. :...
XP_016 AAVSKIAWHVIRNV
410
>>NP_057436 (OMIM: 607635) carboxypeptidase A4 isoform 1 (421 aa)
initn: 959 init1: 433 opt: 1052 Z-score: 1322.2 bits: 253.7 E(85289): 6.6e-67
Smith-Waterman score: 1052; 39.3% identity (71.2% similar) in 420 aa overlap (19-432:3-416)
10 20 30 40 50
pF1KE5 MKCLGKRRGQAAAFLPLCWLFLKILQPGHSHLYNNRYAGDKVIRFIPKTEEEAYALKKI-
:... : : .... ::.:.:. .. .: :...
NP_057 MRWILFIGALIGSSICGQEKFFGDQVLRINVRNGDEISKLSQLV
10 20 30 40
60 70 80 90 100 110
pF1KE5 -SYQLKVDLWQ-PSSISYVSEGTVTDVHIPQNGSRALLAFLQEANIQYKVLIEDLQKTL-
: .::...:. :::.. .:: .:. . .:. .::. ...: : ::::: :
NP_057 NSNNLKLNFWKSPSSFNRP-----VDVLVPSVSLQAFKSFLRSQGLEYAVTIEDLQALLD
50 60 70 80 90
120 130 140 150 160 170
pF1KE5 -EKGSSLHTQRNRRSLSGYNYEVYHSLEEIQNWMHHLNKTHSGLIHMFSIGRSYEGRCLF
: :.. ..:: ...:: .::::: : . : .. : . .::.:.:.: ..
NP_057 NEDDEMQHNEGQERSSNNFNYGAYHSLEAIYHEMDNIAADFPDLARRVKIGHSFENRPMY
100 110 120 130 140 150
180 190 200 210 220 230
pF1KE5 ILKLGRRSRLKR-AVWIDCGIHAREWIGPAFCQWFVKEALLTYKSDPAMRKMLNHLYFYI
.::.. . ..: :::.. :::.::::. : : ... . :. :::. ..:... ...
NP_057 VLKFSTGKGVRRPAVWLNAGIHSREWISQATAIWTARKIVSDYQRDPAITSILEKMDIFL
160 170 180 190 200 210
240 250 260 270 280 290
pF1KE5 MPVFNVDGYHFSWTNDRFWRKTRSRNSRFRCRGVDANRNWKVKWCDEGASMHPCDDTYCG
.:: : ::: .. :..:.:::::::: : :.: ::::.... .::: .::...: :
NP_057 LPVANPDGYVYTQTQNRLWRKTRSRNPGSSCIGADPNRNWNASFAGKGASDNPCSEVYHG
220 230 240 250 260 270
300 310 320 330 340 350
pF1KE5 PFPESEPEVKAVANFLRKHRKHIRAYLSFHAYAQMLLYPYSYKYATIPNFRCVESAAYKA
: .:: :::.:..:..:: ........:.:.:.:.:::.:. :. . ....: :
NP_057 PHANSEVEVKSVVDFIQKH-GNFKGFIDLHSYSQLLMYPYGYSVKKAPDAEELDKVARLA
280 290 300 310 320 330
360 370 380 390 400 410
pF1KE5 VNALQSVYGVRYRYGPASTTLYVSSGSSMDWAYKNGIPYAFAFELRDTGYFGFLLPEMLI
..:: :: :..:. ::. ::.: .::::.:::: ::: .::.::::::: .::::: :
NP_057 AKALASVSGTEYQVGPTCTTVYPASGSSIDWAYDNGIKFAFTFELRDTGTYGFLLPANQI
340 350 360 370 380 390
420 430
pF1KE5 KPTCTETMLAVKNITMHLLKKCP
:: :: :..:.: :.
NP_057 IPTAEETWLGLKTIMEHVRDNLY
400 410 420
437 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 01:27:04 2016 done: Tue Nov 8 01:27:05 2016
Total Scan time: 6.980 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]