FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE5453, 352 aa
  1>>>pF1KE5453 352 - 352 aa - 352 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 7.0523+/-0.000347; mu= 9.2072+/- 0.022
 mean_var=122.0486+/-24.742, 0's: 0 Z-trim(118.9): 15  B-trim: 616 in 1/51
 Lambda= 0.116093
 statistics sampled from 32418 (32433) to 32418 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.724), E-opt: 0.2 (0.38), width:  16
 Scan time:  8.670

The best scores are:                                      opt bits E(85289)
NP_003747 (OMIM: 603912) eukaryotic translation in ( 352) 2305 396.7 3.9e-110
NP_005796 (OMIM: 607173) 26S proteasome non-ATPase ( 310)  225 48.3 2.6e-05
NP_003745 (OMIM: 603914) eukaryotic translation in ( 357)  185 41.7  0.0031


>>NP_003747 (OMIM: 603912) eukaryotic translation initia  (352 aa)
 initn: 2305 init1: 2305 opt: 2305  Z-score: 2098.2  bits: 396.7 E(85289): 3.9e-110
Smith-Waterman score: 2305; 100.0% identity (100.0% similar) in 352 aa overlap (1-352:1-352)

               10        20        30        40        50        60
pF1KE5 MASRKEGTGSTATSSSSTAGAAGKGKGKGGSGDSAVKQVQIDGLVVLKIIKHYQEEGQGT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MASRKEGTGSTATSSSSTAGAAGKGKGKGGSGDSAVKQVQIDGLVVLKIIKHYQEEGQGT
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE5 EVVQGVLLGLVVEDRLEITNCFPFPQHTEDDADFDEVQYQMEMMRSLRHVNIDHLHVGWY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 EVVQGVLLGLVVEDRLEITNCFPFPQHTEDDADFDEVQYQMEMMRSLRHVNIDHLHVGWY
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE5 QSTYYGSFVTRALLDSQFSYQHAIEESVVLIYDPIKTAQGSLSLKAYRLTPKLMEVCKEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 QSTYYGSFVTRALLDSQFSYQHAIEESVVLIYDPIKTAQGSLSLKAYRLTPKLMEVCKEK
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE5 DFSPEALKKANITFEYMFEEVPIVIKNSHLINVLMWELEKKSAVADKHELLSLASSNHLG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 DFSPEALKKANITFEYMFEEVPIVIKNSHLINVLMWELEKKSAVADKHELLSLASSNHLG
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE5 KNLQLLMDRVDEMSQDIVKYNTYMRNTSKQQQQKHQYQQRRQQENMQRQSRGEPPLPEED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 KNLQLLMDRVDEMSQDIVKYNTYMRNTSKQQQQKHQYQQRRQQENMQRQSRGEPPLPEED
              250       260       270       280       290       300

              310       320       330       340       350  
pF1KE5 LSKLFKPPQPPARMDSLLIAGQINTYCQNIKEFTAQNLGKLFMAQALQEYNN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LSKLFKPPQPPARMDSLLIAGQINTYCQNIKEFTAQNLGKLFMAQALQEYNN
              310       320       330       340       350  

>>NP_005796 (OMIM: 607173) 26S proteasome non-ATPase reg  (310 aa)
 initn: 122 init1:  74 opt: 225  Z-score: 216.2  bits: 48.3 E(85289): 2.6e-05
Smith-Waterman score: 244; 24.7% identity (59.7% similar) in 283 aa overlap (20-275:8-283)

               10        20        30            40        50      
pF1KE5 MASRKEGTGSTATSSSSTAGAAGKGKGKGGSGDS-AV---KQVQIDGLVVLKIIKHYQEE
                          :..  : :.:   :. ::   .:: :..:..::..:: .  
NP_005             MDRLLRLGGGMPGLGQGPPTDAPAVDTAEQVYISSLALLKMLKHGRA-
                           10        20        30        40        

         60        70         80        90         100       110   
pF1KE5 GQGTEVVQGVLLGLVVEDR-LEITNCFPFPQHTEDDADFDEVQ--YQMEMMRSLRHVNID
       :   ::. :..::  :.:  ... . : .:: .   .. . :.  .: .:.  :....  
NP_005 GVPMEVM-GLMLGEFVDDYTVRVIDVFAMPQ-SGTGVSVEAVDPVFQAKMLDMLKQTGRP
        50         60        70         80        90       100     

           120        130       140       150       160       170  
pF1KE5 HLHVGWYQS-TYYGSFVTRALLDSQFSYQHAIEESVVLIYDPIKTAQGSLSLKAYRLTPK
       .. ::::.:   .: ... . ...: :..   :..:... :::....:.. . :.::   
NP_005 EMVVGWYHSHPGFGCWLSGVDINTQQSFEALSERAVAVVVDPIQSVKGKVVIDAFRLINA
         110       120       130       140       150       160     

            180           190            200       210       220   
pF1KE5 LMEVCKEKDFSPEA----LKKANIT-----FEYMFEEVPIVIKNSHLINVLMWELEKKS-
        : :  ..  .  .    :.: .:      ..  .  . :  ....: . .. .:.::: 
NP_005 NMMVLGHEPRQTTSNLGHLNKPSIQALIHGLNRHYYSITINYRKNELEQKMLLNLHKKSW
         170       180       190       200       210       220     

                     230       240       250       260       270   
pF1KE5 ----AVAD-----KHELLSLASSNHLGKNLQLLMDRVDEMSQDIVKYNTYMRNTSKQQQQ
           .. :     ::.   .    .:.:: .  ... :.:. . .     ..:..::. .
NP_005 MEGLTLQDYSEHCKHNESVVKEMLELAKNYNKAVEEEDKMTPEQLA----IKNVGKQDPK
         230       240       250       260       270           280 

           280       290       300       310       320       330   
pF1KE5 KHQYQQRRQQENMQRQSRGEPPLPEEDLSKLFKPPQPPARMDSLLIAGQINTYCQNIKEF
       .:                                                          
NP_005 RHLEEHVDVLMTSNIVQCLAAMLDTVVFK                               
             290       300       310                               

>>NP_003745 (OMIM: 603914) eukaryotic translation initia  (357 aa)
 initn: 163 init1: 116 opt: 185  Z-score: 179.1  bits: 41.7 E(85289): 0.0031
Smith-Waterman score: 185; 26.9% identity (56.7% similar) in 201 aa overlap (13-206:72-254)

                                 10        20        30        40  
pF1KE5                   MASRKEGTGSTATSSSSTAGAAGKGKGKGGSGDSAVKQVQID
                                     : . .  : :  :   ::      . :.. 
NP_003 APASSSDPAAAAAATAAPGQTPASAQAPAQTPAPALPGPALPGPFPGG------RVVRLH
              50        60        70        80              90     

             50        60        70        80        90       100  
pF1KE5 GLVVLKIIKHYQEEGQGTEVVQGVLLGLVVEDRLEITNCFPFPQHTEDDADFDEVQYQME
        ... .:.  :.....:.  : :.::: : .  .:.::::  : :.:..   :::  .::
NP_003 PVILASIVDSYERRNEGAARVIGTLLGTVDKHSVEVTNCFSVP-HNESE---DEVAVDME
         100       110       120       130        140          150 

                110       120       130       140       150        
pF1KE5 MMRSL----RHVNIDHLHVGWYQSTYYGSFVTRALLDSQFSYQHAIEESVVLIYDPIKTA
       . ...    ..:. ..: .::: . .  ... ...:  .. :..   . . :  :  .  
NP_003 FAKNMYELHKKVSPNELILGWYATGH--DITEHSVLIHEY-YSREAPNPIHLTVDT-SLQ
             160       170         180        190       200        

      160       170       180          190       200       210     
pF1KE5 QGSLSLKAYRLTPKLMEVCKEKD---FSPEALKKANITFEYMFEEVPIVIKNSHLINVLM
       .: .:.:::  :  :: :  .     :.: ..: :    : .   : ...:         
NP_003 NGRMSIKAYVST--LMGVPGRTMGVMFTPLTVKYAYYDTERI--GVDLIMKTCFSPNRVI
       210         220       230       240         250       260   

         220       230       240       250       260       270     
pF1KE5 WELEKKSAVADKHELLSLASSNHLGKNLQLLMDRVDEMSQDIVKYNTYMRNTSKQQQQKH
                                                                   
NP_003 GLSSDLQQVGGASARIQDALSTVLQYAEDVLSGKVSADNTVGRFLMSLVNQVPKIVPDDF
           270       280       290       300       310       320   




352 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Tue Nov  8 00:55:09 2016 done: Tue Nov  8 00:55:10 2016
 Total Scan time:  8.670 Total Display time:  0.000

Function used was FASTA [36.3.4 Apr, 2011]