Result of FASTA (ccds) for
pFN21AE5448
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5448, 334 aa
1>>>pF1KE5448 334 - 334 aa - 334 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.3220+/-0.000905; mu= 15.6775+/- 0.054
mean_var=62.8614+/-12.661, 0's: 0 Z-trim(105.1): 23 B-trim: 0 in 0/49
Lambda= 0.161764
statistics sampled from 8216 (8234) to 8216 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.636), E-opt: 0.2 (0.253), width: 16
Scan time: 2.210
The best scores are: opt bits E(32554)
CCDS6723.1 CTSV gene_id:1515|Hs108|chr9 ( 334) 2327 551.8 2.9e-157
CCDS6675.1 CTSL gene_id:1514|Hs108|chr9 ( 333) 1836 437.2 9e-123
CCDS969.1 CTSK gene_id:1513|Hs108|chr1 ( 329) 1130 272.4 3.5e-73
CCDS968.1 CTSS gene_id:1520|Hs108|chr1 ( 331) 1116 269.2 3.4e-72
CCDS55634.1 CTSS gene_id:1520|Hs108|chr1 ( 281) 795 194.2 1.1e-49
CCDS10308.1 CTSH gene_id:1512|Hs108|chr15 ( 335) 790 193.1 2.8e-49
CCDS8144.1 CTSF gene_id:8722|Hs108|chr11 ( 484) 641 158.4 1.1e-38
CCDS3794.1 CTSO gene_id:1519|Hs108|chr4 ( 321) 499 125.2 7.4e-29
CCDS8282.1 CTSC gene_id:1075|Hs108|chr11 ( 463) 452 114.3 2e-25
CCDS8117.1 CTSW gene_id:1521|Hs108|chr11 ( 376) 400 102.1 7.6e-22
CCDS13474.1 CTSZ gene_id:1522|Hs108|chr20 ( 303) 298 78.2 9.3e-15
>>CCDS6723.1 CTSV gene_id:1515|Hs108|chr9 (334 aa)
initn: 2327 init1: 2327 opt: 2327 Z-score: 2936.9 bits: 551.8 E(32554): 2.9e-157
Smith-Waterman score: 2327; 100.0% identity (100.0% similar) in 334 aa overlap (1-334:1-334)
10 20 30 40 50 60
pF1KE5 MNLSLVLAAFCLGIASAVPKFDQNLDTKWYQWKATHRRLYGANEEGWRRAVWEKNMKMIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS67 MNLSLVLAAFCLGIASAVPKFDQNLDTKWYQWKATHRRLYGANEEGWRRAVWEKNMKMIE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 LHNGEYSQGKHGFTMAMNAFGDMTNEEFRQMMGCFRNQKFRKGKVFREPLFLDLPKSVDW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS67 LHNGEYSQGKHGFTMAMNAFGDMTNEEFRQMMGCFRNQKFRKGKVFREPLFLDLPKSVDW
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 RKKGYVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS67 RKKGYVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCNG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 GFMARAFQYVKENGGLDSEESYPYVAVDEICKYRPENSVANDTGFTVVAPGKEKALMKAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS67 GFMARAFQYVKENGGLDSEESYPYVAVDEICKYRPENSVANDTGFTVVAPGKEKALMKAV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 ATVGPISVAMDAGHSSFQFYKSGIYFEPDCSSKNLDHGVLVVGYGFEGANSNNSKYWLVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS67 ATVGPISVAMDAGHSSFQFYKSGIYFEPDCSSKNLDHGVLVVGYGFEGANSNNSKYWLVK
250 260 270 280 290 300
310 320 330
pF1KE5 NSWGPEWGSNGYVKIAKDKNNHCGIATAASYPNV
::::::::::::::::::::::::::::::::::
CCDS67 NSWGPEWGSNGYVKIAKDKNNHCGIATAASYPNV
310 320 330
>>CCDS6675.1 CTSL gene_id:1514|Hs108|chr9 (333 aa)
initn: 1824 init1: 1251 opt: 1836 Z-score: 2317.6 bits: 437.2 E(32554): 9e-123
Smith-Waterman score: 1836; 77.5% identity (90.7% similar) in 334 aa overlap (1-334:1-333)
10 20 30 40 50 60
pF1KE5 MNLSLVLAAFCLGIASAVPKFDQNLDTKWYQWKATHRRLYGANEEGWRRAVWEKNMKMIE
:: .:.:::::::::::. ::..:...: .::: : :::: ::::::::::::::::::
CCDS66 MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 LHNGEYSQGKHGFTMAMNAFGDMTNEEFRQMMGCFRNQKFRKGKVFREPLFLDLPKSVDW
::: :: .:::.::::::::::::.:::::.:. :.:.: ::::::.:::: . :.::::
CCDS66 LHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDW
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 RKKGYVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCNG
:.:::::::::: :::::::::::::::::::::::.:.::::::::::: ::::.::::
CCDS66 REKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 GFMARAFQYVKENGGLDSEESYPYVAVDEICKYRPENSVANDTGFTVVAPGKEKALMKAV
:.: :::::..:::::::::::: :..: ::: :. :::::::: : : .::::::::
CCDS66 GLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGF-VDIPKQEKALMKAV
190 200 210 220 230
250 260 270 280 290 300
pF1KE5 ATVGPISVAMDAGHSSFQFYKSGIYFEPDCSSKNLDHGVLVVGYGFEGANSNNSKYWLVK
:::::::::.:::: :: ::: ::::::::::...::::::::::::...:.:.::::::
CCDS66 ATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVK
240 250 260 270 280 290
310 320 330
pF1KE5 NSWGPEWGSNGYVKIAKDKNNHCGIATAASYPNV
:::: ::: .::::.:::. ::::::.:::::.:
CCDS66 NSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
300 310 320 330
>>CCDS969.1 CTSK gene_id:1513|Hs108|chr1 (329 aa)
initn: 1121 init1: 447 opt: 1130 Z-score: 1427.3 bits: 272.4 E(32554): 3.5e-73
Smith-Waterman score: 1130; 50.6% identity (76.5% similar) in 332 aa overlap (7-334:4-329)
10 20 30 40 50
pF1KE5 MNLSLVLAAFCLGIASAVPKFDQNLDTKWYQWKATHRRLYGAN-EEGWRRAVWEKNMKMI
: .. : ..: . .. :::.: :: :::. :. . .: :: .::::.:.:
CCDS96 MWGLKVLLLPVVSFALYPEEILDTHWELWKKTHRKQYNNKVDEISRRLIWEKNLKYI
10 20 30 40 50
60 70 80 90 100 110
pF1KE5 ELHNGEYSQGKHGFTMAMNAFGDMTNEEFRQMMGCFRN--QKFRKGKVFREPLFLD-LPK
.:: : : : : . .::: .::::.:: : : .. .. :.. .. : . :
CCDS96 SIHNLEASLGVHTYELAMNHLGDMTSEEVVQKMTGLKVPLSHSRSNDTLYIPEWEGRAPD
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE5 SVDWRKKGYVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQ
:::.:::::::::::: :::::::::..::::::. .:::::..:: :::::: :.
CCDS96 SVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSE--ND
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE5 GCNGGFMARAFQYVKENGGLDSEESYPYVAVDEICKYRPENSVANDTGFTVVAPGKEKAL
::.::.:. :::::..: :.:::..::::. .: : : : ...:. :. . :.::::
CCDS96 GCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKAL
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE5 MKAVATVGPISVAMDAGHSSFQFYKSGIYFEPDCSSKNLDHGVLVVGYGFEGANSNNSKY
.::: :::.:::.::. .:::::..:.:.. .:.: ::.:.::.::::.. .: :.
CCDS96 KRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGN----KH
240 250 260 270 280 290
300 310 320 330
pF1KE5 WLVKNSWGPEWGSNGYVKIAKDKNNHCGIATAASYPNV
:..::::: .::..::. .:..::: ::::. ::.:..
CCDS96 WIIKNSWGENWGNKGYILMARNKNNACGIANLASFPKM
300 310 320
>>CCDS968.1 CTSS gene_id:1520|Hs108|chr1 (331 aa)
initn: 1056 init1: 363 opt: 1116 Z-score: 1409.6 bits: 269.2 E(32554): 3.4e-72
Smith-Waterman score: 1116; 50.5% identity (77.5% similar) in 325 aa overlap (15-334:12-331)
10 20 30 40 50
pF1KE5 MNLSLVLAAFCLGIASAVPKF--DQNLDTKWYQWKATHRRLYGA-NEEGWRRAVWEKNMK
.::: .. : .:: .:. :: :. . : :::. :: .::::.:
CCDS96 MKRLVCVLLVCSSAVAQLHKDPTLDHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLK
10 20 30 40 50
60 70 80 90 100 110
pF1KE5 MIELHNGEYSQGKHGFTMAMNAFGDMTNEEFRQMMGCFR-NQKFRKGKVFREPLFLDLPK
.. ::: :.:.: :.. ..:: .::::.:: ..:. .: ...... ... ::
CCDS96 FVMLHNLEHSMGMHSYDLGMNHLGDMTSEEVMSLMSSLRVPSQWQRNITYKSNPNRILPD
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE5 SVDWRKKGYVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQ-GN
:::::.:: :: :: : .::.::::::.::::.:. ::::::::: ::::::: . ::
CCDS96 SVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGN
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE5 QGCNGGFMARAFQYVKENGGLDSEESYPYVAVDEICKYRPENSVANDTGFTVVAPGKEKA
.:::::::. ::::. .: :.::. :::: :.:. :.: . .:. . .: . :.: .
CCDS96 KGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDV
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE5 LMKAVATVGPISVAMDAGHSSFQFYKSGIYFEPDCSSKNLDHGVLVVGYGFEGANSNNSK
: .:::. ::.::..:: : :: .:.::.:.::.:. .:..::::::::: . :...
CCDS96 LKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCT-QNVNHGVLVVGYG----DLNGKE
240 250 260 270 280 290
300 310 320 330
pF1KE5 YWLVKNSWGPEWGSNGYVKIAKDKNNHCGIATAASYPNV
::::::::: ..: .::...:..:.::::::. :::..
CCDS96 YWLVKNSWGHNFGEEGYIRMARNKGNHCGIASFPSYPEI
300 310 320 330
>>CCDS55634.1 CTSS gene_id:1520|Hs108|chr1 (281 aa)
initn: 880 init1: 363 opt: 795 Z-score: 1005.8 bits: 194.2 E(32554): 1.1e-49
Smith-Waterman score: 907; 44.8% identity (67.3% similar) in 324 aa overlap (15-334:12-281)
10 20 30 40 50
pF1KE5 MNLSLVLAAFCLGIASAVPKF--DQNLDTKWYQWKATHRRLYGA-NEEGWRRAVWEKNMK
.::: .. : .:: .:. :: :. . : :::. :: .::::.:
CCDS55 MKRLVCVLLVCSSAVAQLHKDPTLDHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLK
10 20 30 40 50
60 70 80 90 100 110
pF1KE5 MIELHNGEYSQGKHGFTMAMNAFGDMTNEEFRQMMGCFRNQKFRKGKVFREPLFLDLPKS
.. ::: :.:.: :.. ..:: .::: .
CCDS55 FVMLHNLEHSMGMHSYDLGMNHLGDMGS--------------------------------
60 70 80
120 130 140 150 160 170
pF1KE5 VDWRKKGYVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQ-GNQ
::.::::::.::::.:. ::::::::: ::::::: . ::.
CCDS55 -----------------CGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNK
90 100 110 120
180 190 200 210 220 230
pF1KE5 GCNGGFMARAFQYVKENGGLDSEESYPYVAVDEICKYRPENSVANDTGFTVVAPGKEKAL
:::::::. ::::. .: :.::. :::: :.:. :.: . .:. . .: . :.: .:
CCDS55 GCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVL
130 140 150 160 170 180
240 250 260 270 280 290
pF1KE5 MKAVATVGPISVAMDAGHSSFQFYKSGIYFEPDCSSKNLDHGVLVVGYGFEGANSNNSKY
.:::. ::.::..:: : :: .:.::.:.::.:. .:..::::::::: . :...:
CCDS55 KEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCT-QNVNHGVLVVGYG----DLNGKEY
190 200 210 220 230 240
300 310 320 330
pF1KE5 WLVKNSWGPEWGSNGYVKIAKDKNNHCGIATAASYPNV
:::::::: ..: .::...:..:.::::::. :::..
CCDS55 WLVKNSWGHNFGEEGYIRMARNKGNHCGIASFPSYPEI
250 260 270 280
>>CCDS10308.1 CTSH gene_id:1512|Hs108|chr15 (335 aa)
initn: 675 init1: 382 opt: 790 Z-score: 998.3 bits: 193.1 E(32554): 2.8e-49
Smith-Waterman score: 790; 40.8% identity (69.9% similar) in 306 aa overlap (32-332:38-331)
10 20 30 40 50 60
pF1KE5 NLSLVLAAFCLGIASAVPKFDQNLDTKWYQWKATHRRLYGANEEGWRRAVWEKNMKMIEL
: . ::. :...: : .. .: . :.
CCDS10 LCAGAWLLGVPVCGAAELCVNSLEKFHFKSWMSKHRKTYSTEEYHHRLQTFASNWRKINA
10 20 30 40 50 60
70 80 90 100 110
pF1KE5 HNGEYSQGKHGFTMAMNAFGDMTNEEFRQ--MMGCFRNQKFRKGKVFREPLFLDLPKSVD
::. :.: : ::.: :.::. :... . . .: . :.. .: : :::
CCDS10 HNN----GNHTFKMALNQFSDMSFAEIKHKYLWSEPQNCSATKSNYLRGTG--PYPPSVD
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE5 WRKKG-YVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGC
::::: .:.::::: :::::.::.:::::. . :::..::.::.::::.. .:.::
CCDS10 WRKKGNFVSPVKNQGACGSCWTFSTTGALESAIAIATGKMLSLAEQQLVDCAQDFNNHGC
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE5 NGGFMARAFQYVKENGGLDSEESYPYVAVDEICKYRPENSVANDTGFTVVAPGKEKALMK
.::. ..::.:. : :. .:..::: . : ::..: .... . .. :.:...
CCDS10 QGGLPSQAFEYILYNKGIMGEDTYPYQGKDGYCKFQPGKAIGFVKDVANITIYDEEAMVE
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE5 AVATVGPISVAMDAGHSSFQFYKSGIYFEPDC--SSKNLDHGVLVVGYGFEGANSNNSKY
::: .:.: :... .. :..:..::: .: . ...:.::.:::: ..:. :
CCDS10 AVALYNPVSFAFEVTQD-FMMYRTGIYSSTSCHKTPDKVNHAVLAVGYG----EKNGIPY
250 260 270 280 290
300 310 320 330
pF1KE5 WLVKNSWGPEWGSNGYVKIAKDKNNHCGIATAASYPNV
:.:::::::.:: ::: : . :: ::.:. ::::
CCDS10 WIVKNSWGPQWGMNGYFLIERGKN-MCGLAACASYPIPLV
300 310 320 330
>>CCDS8144.1 CTSF gene_id:8722|Hs108|chr11 (484 aa)
initn: 541 init1: 249 opt: 641 Z-score: 807.9 bits: 158.4 E(32554): 1.1e-38
Smith-Waterman score: 641; 38.6% identity (65.4% similar) in 306 aa overlap (35-330:193-479)
10 20 30 40 50 60
pF1KE5 LVLAAFCLGIASAVPKFDQNLDTKWYQWKATHRRLYGANEEG-WRRAVWEKNM-KMIELH
:. : : ..::. :: .:. .:: . ...
CCDS81 FSSVISLLNEDPLSQDLPVKMASIFKNFVITYNRTYESKEEARWRLSVFVNNMVRAQKIQ
170 180 190 200 210 220
70 80 90 100 110
pF1KE5 NGEYSQGKHGFTMAMNAFGDMTNEEFRQMMGCFRNQKFRK--GKVFREPLFL-DL-PKSV
. . ...: : :.:.:.:::: . . : .:: :. ... . :: :
CCDS81 ALDRGTAQYGVT----KFSDLTEEEFRTI---YLNTLLRKEPGNKMKQAKSVGDLAPPEW
230 240 250 260 270
120 130 140 150 160 170
pF1KE5 DWRKKGYVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGC
:::.:: :: ::.: .::::::::.:: .::: : . : :.:::::.:.::.. ...:
CCDS81 DWRSKGAVTKVKDQGMCGSCWAFSVTGNVEGQWFLNQGTLLSLSEQELLDCDKM--DKAC
280 290 300 310 320 330
180 190 200 210 220 230
pF1KE5 NGGFMARAFQYVKENGGLDSEESYPYVAVDEICKYRPENS--VANDTGFTVVAPGKEKAL
::. . :.. .:. :::..:..: : . . :.. :.. ::. : .:. :
CCDS81 MGGLPSNAYSAIKNLGGLETEDDYSYQGHMQSCNFSAEKAKVYINDS---VELSQNEQKL
340 350 360 370 380 390
240 250 260 270 280 290
pF1KE5 MKAVATVGPISVAMDAGHSSFQFYKSGIY--FEPDCSSKNLDHGVLVVGYGFEGANSNNS
.: ::::::..: ..:::. :: ..: :: .::.::.:::: : ..
CCDS81 AAWLAKRGPISVAINA--FGMQFYRHGISRPLRPLCSPWLIDHAVLLVGYG----NRSDV
400 410 420 430 440
300 310 320 330
pF1KE5 KYWLVKNSWGPEWGSNGYVKIAKDKNNHCGIATAASYPNV
.: .::::: .:: .:: . . .. ::. : ::
CCDS81 PFWAIKNSWGTDWGEKGYYYLHRG-SGACGVNTMASSAVVD
450 460 470 480
>>CCDS3794.1 CTSO gene_id:1519|Hs108|chr4 (321 aa)
initn: 444 init1: 203 opt: 499 Z-score: 631.6 bits: 125.2 E(32554): 7.4e-29
Smith-Waterman score: 499; 35.3% identity (63.2% similar) in 269 aa overlap (67-330:60-317)
40 50 60 70 80 90
pF1KE5 RRLYGANEEGWRRAVWEKNMKMIELHNGEYSQGKHGFTMAMNAFGDMTNEEFRQMMGCFR
:... .: ...: :. . :::. .. .
CCDS37 TPTWPRSREREAAAFRESLNRHRYLNSLFPSENSTAF-YGINQFSYLFPEEFKAIYLRSK
30 40 50 60 70 80
100 110 120 130 140 150
pF1KE5 NQKFRK--GKVFREPLFLDLPKSVDWRKKGYVTPVKNQKQCGSCWAFSATGALEGQMFRK
.:: . ..: ..:: ::: : :: :.::..::.:::::..::.:. . :
CCDS37 PSKFPRYSAEVHMSIPNVSLPLRFDWRDKQVVTQVRNQQMCGGCWAFSVVGAVESAYAIK
90 100 110 120 130 140
160 170 180 190 200 210
pF1KE5 TGKLVSLSEQNLVDCSRPQGNQGCNGGFMARAFQYV-KENGGLDSEESYPYVAVDEICKY
: .:: :...::: .: ::::: :.... : . : .. ::. : . .:.:
CCDS37 GKPLEDLSVQQVIDCSY--NNYGCNGGSTLNALNWLNKMQVKLVKDSEYPFKAQNGLCHY
150 160 170 180 190 200
220 230 240 250 260 270
pF1KE5 -RPENSVANDTGFTVVA-PGKEKALMKAVATVGPISVAMDAGHSSFQFYKSGIYFEPDCS
.: . :... .: . ::. : ::. : .:: :.: : .:: .. ::
CCDS37 FSGSHSGFSIKGYSAYDFSDQEDEMAKALLTFGPLVVIVDA--VSWQDYLGGI-IQHHCS
210 220 230 240 250 260
280 290 300 310 320 330
pF1KE5 SKNLDHGVLVVGYGFEGANSNNSKYWLVKNSWGPEWGSNGYVKIAKDKNNHCGIATAASY
: . .:.::..:. : .. ::.:.:::: :: .::... : .: :::: ..:
CCDS37 SGEANHAVLITGFDKTG----STPYWIVRNSWGSSWGVDGYAHV-KMGSNVCGIADSVSS
270 280 290 300 310
pF1KE5 PNV
CCDS37 IFV
320
>>CCDS8282.1 CTSC gene_id:1075|Hs108|chr11 (463 aa)
initn: 394 init1: 170 opt: 452 Z-score: 569.8 bits: 114.3 E(32554): 2e-25
Smith-Waterman score: 453; 31.3% identity (59.7% similar) in 335 aa overlap (26-329:128-454)
10 20 30 40 50
pF1KE5 MNLSLVLAAFCLGIASAVPKFDQNLDTKWYQWKA-THRRLYGANEEGWRRAVWEK
:. .: : ... :.:. . . :
CCDS82 DYKWFAFFKYKEEGSKVTTYCNETMTGWVHDVLGRNWACFTGKKVGTASENVYVNIAHLK
100 110 120 130 140 150
60 70 80 90 100
pF1KE5 NMKMIELHNGEYSQGKHGFTMAMNAFGD----MTNEEFRQM-MG-CFRNQKFRKGKVFRE
: . : .... . :.:. :.::. : :.. . .: .: . .. :. :
CCDS82 NSQ--EKYSNRLYKYDHNFVKAINAIQKSWTATTYMEYETLTLGDMIRRSGGHSRKIPRP
160 170 180 190 200 210
110 120 130 140 150
pF1KE5 ---PL-------FLDLPKSVDWRK-KG--YVTPVKNQKQCGSCWAFSATGALEGQM--FR
:: .: :: : :::. .: .:.::.:: .::::..:.. : ::... .
CCDS82 KPAPLTAEIQQKILHLPTSWDWRNVHGINFVSPVRNQASCGSCYSFASMGMLEARIRILT
220 230 240 250 260 270
160 170 180 190 200 210
pF1KE5 KTGKLVSLSEQNLVDCSRPQGNQGCNGGFMARAFQYVKENGGLDSEESYPYVAVDEICKY
.... :: :..:.:: : :::.::: .. :: : .::...: ::.
CCDS82 NNSQTPILSPQEVVSCS--QYAQGCEGGFPYLIAGKYAQDFGLVEEACFPYTGTDSPCKM
280 290 300 310 320 330
220 230 240 250 260
pF1KE5 RPENSVANDTGFTVVAP---GKEKALMK-AVATVGPISVAMDAGHSSFQFYKSGIYF---
. . .. . :. : ..:::: .. ::..::... ...: ::.:::
CCDS82 KEDCFRYYSSEYHYVGGFYGGCNEALMKLELVHHGPMAVAFEV-YDDFLHYKKGIYHHTG
340 350 360 370 380 390
270 280 290 300 310 320
pF1KE5 --EPDCSSKNLDHGVLVVGYGFEGANSNNSKYWLVKNSWGPEWGSNGYVKIAKDKNNHCG
.: . .:.::.:::: ..:.. . ::.:::::: :: ::: .: . ...:.
CCDS82 LRDPFNPFELTNHAVLLVGYGTDSASGMD--YWIVKNSWGTGWGENGYFRIRRG-TDECA
400 410 420 430 440
330
pF1KE5 IATAASYPNV
: . :
CCDS82 IESIAVAATPIPKL
450 460
>>CCDS8117.1 CTSW gene_id:1521|Hs108|chr11 (376 aa)
initn: 428 init1: 139 opt: 400 Z-score: 505.6 bits: 102.1 E(32554): 7.6e-22
Smith-Waterman score: 492; 31.5% identity (60.8% similar) in 355 aa overlap (3-325:11-354)
10 20 30 40
pF1KE5 MNLSLVLAAFCLGIASAVPKFD---QNLDTK--WYQWKATHRRLYGANEEGW
:.:..:.. :: . . : : :. : . .. : : . ::
CCDS81 MALTAHPSCLLALLVAGLAQGIRGPLRAQDLGPQPLELKEAFKLFQIQFNRSYLSPEEHA
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE5 RRA-VWEKNMKMIE-LHNGEYSQGKHGFTMAMNAFGDMTNEEFRQMMGCFRNQKF--RKG
.: .. .:. . . :.. . . .. : : :.:.:.::: :..: : :
CCDS81 HRLDIFAHNLAQAQRLQEEDLGTAEFGVT----PFSDLTEEEFGQLYGYRRAAGGVPSMG
70 80 90 100 110
110 120 130 140 150 160
pF1KE5 KVFR--EPLFLDLPKSVDWRK-KGYVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKLVS
. .: :: ..: : :::: . ..:.:.::.:. :::..:.: .: . .:.
CCDS81 REIRSEEPEE-SVPFSCDWRKVASAISPIKDQKNCNCCWAMAAAGNIETLWRISFWDFVD
120 130 140 150 160 170
170 180 190 200 210
pF1KE5 LSEQNLVDCSRPQGNQGCNGGFMARAFQYVKENGGLDSEESYPYVAVDEI--CKYRPENS
.: :.:.::.: ..::.:::. :: : .:.:: ::..::. . . :. . ..
CCDS81 VSVQELLDCGR--CGDGCHGGFVWDAFITVLNNSGLASEKDYPFQGKVRAHRCHPKKYQK
180 190 200 210 220 230
220 230 240 250 260 270
pF1KE5 VANDTGFTVVAPGKEKALMKAVATVGPISVAMDAGHSSFQFYKSGIY-FEPD-CSSKNLD
:: : .. ..:. . . .:: :::.:... . .:.:..:. : :. . .:
CCDS81 VAWIQDF-IMLQNNEHRIAQYLATYGPITVTINM--KPLQLYRKGVIKATPTTCDPQLVD
240 250 260 270 280 290
280 290 300 310 320
pF1KE5 HGVLVVGYGF----EG--ANSNNSK----------YWLVKNSWGPEWGSNGYVKIAKDKN
:.::.::.: :: :.. .:. ::..::::: .:: .:: .. . .:
CCDS81 HSVLLVGFGSVKSEEGIWAETVSSQSQPQPPHPTPYWILKNSWGAQWGEKGYFRLHRGSN
300 310 320 330 340 350
330
pF1KE5 NHCGIATAASYPNV
. :::
CCDS81 T-CGITKFPLTARVQKPDMKPRVSCPP
360 370
334 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 00:52:09 2016 done: Tue Nov 8 00:52:10 2016
Total Scan time: 2.210 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]