FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE5437, 351 aa
  1>>>pF1KE5437 351 - 351 aa - 351 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.1899+/-0.000333; mu= 13.2560+/- 0.021
 mean_var=94.2396+/-18.562, 0's: 0 Z-trim(116.7): 5  B-trim: 0 in 0/55
 Lambda= 0.132117
 statistics sampled from 27998 (28002) to 27998 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.68), E-opt: 0.2 (0.328), width:  16
 Scan time:  7.480

The best scores are:                                      opt bits E(85289)
NP_612366 (OMIM: 614197) calcium uniporter protein ( 351) 2329 453.8 2.5e-127
NP_001257609 (OMIM: 614197) calcium uniporter prot ( 302) 1983 387.8 1.6e-107
XP_016872371 (OMIM: 614197) PREDICTED: calcium uni ( 358) 1984 388.1 1.6e-107
NP_001257608 (OMIM: 614197) calcium uniporter prot ( 330) 1107 220.9 3.2e-57


>>NP_612366 (OMIM: 614197) calcium uniporter protein, mi  (351 aa)
 initn: 2329 init1: 2329 opt: 2329  Z-score: 2406.8  bits: 453.8 E(85289): 2.5e-127
Smith-Waterman score: 2329; 100.0% identity (100.0% similar) in 351 aa overlap (1-351:1-351)

               10        20        30        40        50        60
pF1KE5 MAAAAGRSLLLLLSSRGGGGGGAGGCGALTAGCFPGLGVSRHRQQQHHRTVHQRIASWQN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 MAAAAGRSLLLLLSSRGGGGGGAGGCGALTAGCFPGLGVSRHRQQQHHRTVHQRIASWQN
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE5 LGAVYCSTVVPSDDVTVVYQNGLPVISVRLPSRRERCQFTLKPISDSVGVFLRQLQEEDR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 LGAVYCSTVVPSDDVTVVYQNGLPVISVRLPSRRERCQFTLKPISDSVGVFLRQLQEEDR
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE5 GIDRVAIYSPDGVRVAASTGIDLLLLDDFKLVINDLTYHVRPPKRDLLSHENAATLNDVK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 GIDRVAIYSPDGVRVAASTGIDLLLLDDFKLVINDLTYHVRPPKRDLLSHENAATLNDVK
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE5 TLVQQLYTTLCIEQHQLNKERELIERLEDLKEQLAPLEKVRIEISRKAEKRTTLVLWGGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 TLVQQLYTTLCIEQHQLNKERELIERLEDLKEQLAPLEKVRIEISRKAEKRTTLVLWGGL
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE5 AYMATQFGILARLTWWEYSWDIMEPVTYFITYGSAMAMYAYFVMTRQEYVYPEARDRQYL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 AYMATQFGILARLTWWEYSWDIMEPVTYFITYGSAMAMYAYFVMTRQEYVYPEARDRQYL
              250       260       270       280       290       300

              310       320       330       340       350 
pF1KE5 LFFHKGAKKSRFDLEKYNQLKDAIAQAEMDLKRLRDPLQVHLPLRQIGEKD
       :::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 LFFHKGAKKSRFDLEKYNQLKDAIAQAEMDLKRLRDPLQVHLPLRQIGEKD
              310       320       330       340       350 

>>NP_001257609 (OMIM: 614197) calcium uniporter protein,  (302 aa)
 initn: 1983 init1: 1983 opt: 1983  Z-score: 2051.3  bits: 387.8 E(85289): 1.6e-107
Smith-Waterman score: 1983; 100.0% identity (100.0% similar) in 301 aa overlap (51-351:2-302)

               30        40        50        60        70        80
pF1KE5 GGAGGCGALTAGCFPGLGVSRHRQQQHHRTVHQRIASWQNLGAVYCSTVVPSDDVTVVYQ
                                     ::::::::::::::::::::::::::::::
NP_001                              MVHQRIASWQNLGAVYCSTVVPSDDVTVVYQ
                                            10        20        30 

               90       100       110       120       130       140
pF1KE5 NGLPVISVRLPSRRERCQFTLKPISDSVGVFLRQLQEEDRGIDRVAIYSPDGVRVAASTG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NGLPVISVRLPSRRERCQFTLKPISDSVGVFLRQLQEEDRGIDRVAIYSPDGVRVAASTG
              40        50        60        70        80        90 

              150       160       170       180       190       200
pF1KE5 IDLLLLDDFKLVINDLTYHVRPPKRDLLSHENAATLNDVKTLVQQLYTTLCIEQHQLNKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IDLLLLDDFKLVINDLTYHVRPPKRDLLSHENAATLNDVKTLVQQLYTTLCIEQHQLNKE
             100       110       120       130       140       150 

              210       220       230       240       250       260
pF1KE5 RELIERLEDLKEQLAPLEKVRIEISRKAEKRTTLVLWGGLAYMATQFGILARLTWWEYSW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RELIERLEDLKEQLAPLEKVRIEISRKAEKRTTLVLWGGLAYMATQFGILARLTWWEYSW
             160       170       180       190       200       210 

              270       280       290       300       310       320
pF1KE5 DIMEPVTYFITYGSAMAMYAYFVMTRQEYVYPEARDRQYLLFFHKGAKKSRFDLEKYNQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DIMEPVTYFITYGSAMAMYAYFVMTRQEYVYPEARDRQYLLFFHKGAKKSRFDLEKYNQL
             220       230       240       250       260       270 

              330       340       350 
pF1KE5 KDAIAQAEMDLKRLRDPLQVHLPLRQIGEKD
       :::::::::::::::::::::::::::::::
NP_001 KDAIAQAEMDLKRLRDPLQVHLPLRQIGEKD
             280       290       300  

>>XP_016872371 (OMIM: 614197) PREDICTED: calcium uniport  (358 aa)
 initn: 1983 init1: 1983 opt: 1984  Z-score: 2051.3  bits: 388.1 E(85289): 1.6e-107
Smith-Waterman score: 1984; 97.1% identity (98.7% similar) in 311 aa overlap (41-351:48-358)

               20        30        40        50        60        70
pF1KE5 LLLSSRGGGGGGAGGCGALTAGCFPGLGVSRHRQQQHHRTVHQRIASWQNLGAVYCSTVV
                                     : .....   ::::::::::::::::::::
XP_016 SSFTFVFFSLIQIAEGSGGRGEDVESPESWRVERRKKAVKVHQRIASWQNLGAVYCSTVV
        20        30        40        50        60        70       

               80        90       100       110       120       130
pF1KE5 PSDDVTVVYQNGLPVISVRLPSRRERCQFTLKPISDSVGVFLRQLQEEDRGIDRVAIYSP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSDDVTVVYQNGLPVISVRLPSRRERCQFTLKPISDSVGVFLRQLQEEDRGIDRVAIYSP
        80        90       100       110       120       130       

              140       150       160       170       180       190
pF1KE5 DGVRVAASTGIDLLLLDDFKLVINDLTYHVRPPKRDLLSHENAATLNDVKTLVQQLYTTL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DGVRVAASTGIDLLLLDDFKLVINDLTYHVRPPKRDLLSHENAATLNDVKTLVQQLYTTL
       140       150       160       170       180       190       

              200       210       220       230       240       250
pF1KE5 CIEQHQLNKERELIERLEDLKEQLAPLEKVRIEISRKAEKRTTLVLWGGLAYMATQFGIL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CIEQHQLNKERELIERLEDLKEQLAPLEKVRIEISRKAEKRTTLVLWGGLAYMATQFGIL
       200       210       220       230       240       250       

              260       270       280       290       300       310
pF1KE5 ARLTWWEYSWDIMEPVTYFITYGSAMAMYAYFVMTRQEYVYPEARDRQYLLFFHKGAKKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ARLTWWEYSWDIMEPVTYFITYGSAMAMYAYFVMTRQEYVYPEARDRQYLLFFHKGAKKS
       260       270       280       290       300       310       

              320       330       340       350 
pF1KE5 RFDLEKYNQLKDAIAQAEMDLKRLRDPLQVHLPLRQIGEKD
       :::::::::::::::::::::::::::::::::::::::::
XP_016 RFDLEKYNQLKDAIAQAEMDLKRLRDPLQVHLPLRQIGEKD
       320       330       340       350        

>>NP_001257608 (OMIM: 614197) calcium uniporter protein,  (330 aa)
 initn: 1978 init1: 1107 opt: 1107  Z-score: 1148.4  bits: 220.9 E(85289): 3.2e-57
Smith-Waterman score: 1933; 86.0% identity (88.9% similar) in 351 aa overlap (1-351:1-330)

               10        20        30        40        50        60
pF1KE5 MAAAAGRSLLLLLSSRGGGGGGAGGCGALTAGCFPGLGVSRHRQQQHHRTVHQRIASWQN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAAAAGRSLLLLLSSRGGGGGGAGGCGALTAGCFPGLGVSRHRQQQHHRTVHQRIASWQN
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE5 LGAVYCSTVVPSDDVTVVYQNGLPVISVRLPSRRERCQFTLKPISDSVGVFLRQLQEEDR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LGAVYCSTVVPSDDVTVVYQNGLPVISVRLPSRRERCQFTLKPISDSVGVFLRQLQEEDR
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE5 GIDRVAIYSPDGVRVAASTGIDLLLLDDFKLVINDLTYHVRPPKRDLLSHENAATLNDVK
       :::::::::::::::::::::::::::::::::::::::::::::  ..  ...  :  .
NP_001 GIDRVAIYSPDGVRVAASTGIDLLLLDDFKLVINDLTYHVRPPKRVEMGFCHVGQ-NGFE
              130       140       150       160       170          

              190       200       210       220       230       240
pF1KE5 TLVQQLYTTLCIEQHQLNKERELIERLEDLKEQLAPLEKVRIEISRKAEKRTTLVLWGGL
        :...                     :     : : .  :::::::::::::::::::::
NP_001 LLTSSY--------------------LPASASQSAEIIAVRIEISRKAEKRTTLVLWGGL
     180                           190       200       210         

              250       260       270       280       290       300
pF1KE5 AYMATQFGILARLTWWEYSWDIMEPVTYFITYGSAMAMYAYFVMTRQEYVYPEARDRQYL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AYMATQFGILARLTWWEYSWDIMEPVTYFITYGSAMAMYAYFVMTRQEYVYPEARDRQYL
     220       230       240       250       260       270         

              310       320       330       340       350 
pF1KE5 LFFHKGAKKSRFDLEKYNQLKDAIAQAEMDLKRLRDPLQVHLPLRQIGEKD
       :::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LFFHKGAKKSRFDLEKYNQLKDAIAQAEMDLKRLRDPLQVHLPLRQIGEKD
     280       290       300       310       320       330




351 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Tue Nov  8 00:45:14 2016 done: Tue Nov  8 00:45:16 2016
 Total Scan time:  7.480 Total Display time:  0.000

Function used was FASTA [36.3.4 Apr, 2011]