Result of FASTA (omim) for
pFN21AE5406
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5406, 357 aa
1>>>pF1KE5406 357 - 357 aa - 357 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.9295+/-0.000391; mu= 15.1578+/- 0.024
mean_var=162.1598+/-35.386, 0's: 0 Z-trim(116.8): 463 B-trim: 1124 in 2/53
Lambda= 0.100717
statistics sampled from 27647 (28308) to 27647 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.693), E-opt: 0.2 (0.332), width: 16
Scan time: 6.560
The best scores are: opt bits E(85289)
NP_004805 (OMIM: 607797) U5 small nuclear ribonucl ( 357) 2431 365.4 1.1e-100
XP_005246141 (OMIM: 610767,611081) PREDICTED: auto ( 480) 482 82.3 2.4e-15
XP_006712671 (OMIM: 610767,611081) PREDICTED: auto ( 540) 482 82.4 2.6e-15
XP_005246139 (OMIM: 610767,611081) PREDICTED: auto ( 624) 482 82.5 2.8e-15
NP_942593 (OMIM: 610767,611081) autophagy-related ( 444) 476 81.4 4.2e-15
XP_005246143 (OMIM: 610767,611081) PREDICTED: auto ( 463) 476 81.4 4.3e-15
NP_001177196 (OMIM: 610767,611081) autophagy-relat ( 491) 476 81.5 4.5e-15
NP_001177195 (OMIM: 610767,611081) autophagy-relat ( 523) 476 81.5 4.6e-15
NP_060444 (OMIM: 610767,611081) autophagy-related ( 588) 476 81.6 5e-15
NP_110430 (OMIM: 610767,611081) autophagy-related ( 607) 476 81.6 5.1e-15
XP_011531864 (OMIM: 614783,614813) PREDICTED: POC1 ( 300) 447 77.0 6.2e-14
NP_001155052 (OMIM: 614783,614813) POC1 centriolar ( 359) 448 77.2 6.2e-14
NP_056241 (OMIM: 614783,614813) POC1 centriolar pr ( 407) 448 77.3 6.7e-14
XP_011531863 (OMIM: 614783,614813) PREDICTED: POC1 ( 326) 446 76.9 7.2e-14
XP_011531862 (OMIM: 614783,614813) PREDICTED: POC1 ( 374) 446 76.9 7.8e-14
NP_758440 (OMIM: 614784,615973) POC1 centriolar pr ( 478) 435 75.5 2.7e-13
NP_056975 (OMIM: 605585) pre-mRNA-processing facto ( 579) 411 72.1 3.4e-12
NP_001151 (OMIM: 602233) apoptotic protease-activa (1194) 412 72.7 4.8e-12
NP_863658 (OMIM: 602233) apoptotic protease-activa (1205) 412 72.7 4.8e-12
NP_438172 (OMIM: 609012) WD repeat-containing prot ( 334) 404 70.8 5e-12
NP_060058 (OMIM: 609012) WD repeat-containing prot ( 334) 404 70.8 5e-12
XP_005272220 (OMIM: 609012) PREDICTED: WD repeat-c ( 334) 404 70.8 5e-12
XP_016861593 (OMIM: 614783,614813) PREDICTED: POC1 ( 321) 394 69.3 1.3e-11
NP_001155053 (OMIM: 614783,614813) POC1 centriolar ( 369) 394 69.4 1.5e-11
NP_001309196 (OMIM: 607795,615922) U4/U6 small nuc ( 279) 387 68.2 2.5e-11
NP_001309195 (OMIM: 607795,615922) U4/U6 small nuc ( 279) 387 68.2 2.5e-11
NP_001231855 (OMIM: 607795,615922) U4/U6 small nuc ( 521) 387 68.6 3.6e-11
NP_004688 (OMIM: 607795,615922) U4/U6 small nuclea ( 522) 387 68.6 3.6e-11
XP_011531867 (OMIM: 614783,614813) PREDICTED: POC1 ( 246) 369 65.5 1.4e-10
XP_011531866 (OMIM: 614783,614813) PREDICTED: POC1 ( 246) 369 65.5 1.4e-10
XP_011531865 (OMIM: 614783,614813) PREDICTED: POC1 ( 246) 369 65.5 1.4e-10
NP_008882 (OMIM: 601787) transcription initiation ( 800) 371 66.5 2.3e-10
XP_011535412 (OMIM: 601686) PREDICTED: telomerase (2104) 374 67.5 3.1e-10
NP_001308124 (OMIM: 270710,602342,608628,616944) F ( 427) 364 65.1 3.3e-10
NP_001305964 (OMIM: 601686) telomerase protein com (2519) 374 67.6 3.4e-10
NP_009041 (OMIM: 601686) telomerase protein compon (2627) 374 67.6 3.5e-10
XP_005268084 (OMIM: 601686) PREDICTED: telomerase (2627) 374 67.6 3.5e-10
NP_001308123 (OMIM: 270710,602342,608628,616944) F ( 514) 364 65.2 3.6e-10
XP_011511444 (OMIM: 270710,602342,608628,616944) P ( 514) 364 65.2 3.6e-10
NP_078941 (OMIM: 270710,602342,608628,616944) F-bo ( 514) 364 65.2 3.6e-10
XP_006713809 (OMIM: 270710,602342,608628,616944) P ( 514) 364 65.2 3.6e-10
XP_005247832 (OMIM: 270710,602342,608628,616944) P ( 514) 364 65.2 3.6e-10
XP_011511445 (OMIM: 270710,602342,608628,616944) P ( 514) 364 65.2 3.6e-10
XP_011511443 (OMIM: 270710,602342,608628,616944) P ( 514) 364 65.2 3.6e-10
XP_016862674 (OMIM: 270710,602342,608628,616944) P ( 514) 364 65.2 3.6e-10
NP_001308122 (OMIM: 270710,602342,608628,616944) F ( 514) 364 65.2 3.6e-10
NP_037361 (OMIM: 602233) apoptotic protease-activa (1237) 368 66.3 4.1e-10
NP_863651 (OMIM: 602233) apoptotic protease-activa (1248) 368 66.3 4.1e-10
NP_001186706 (OMIM: 614784,615973) POC1 centriolar ( 436) 359 64.4 5.5e-10
NP_599021 (OMIM: 400033) F-box-like/WD repeat-cont ( 522) 355 63.9 9.1e-10
>>NP_004805 (OMIM: 607797) U5 small nuclear ribonucleopr (357 aa)
initn: 2431 init1: 2431 opt: 2431 Z-score: 1928.4 bits: 365.4 E(85289): 1.1e-100
Smith-Waterman score: 2431; 100.0% identity (100.0% similar) in 357 aa overlap (1-357:1-357)
10 20 30 40 50 60
pF1KE5 MIEQQKRKGPELPLVPVKRQRHELLLGAGSGPGAGQQQATPGALLQAGPPRCSSLQAPIM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MIEQQKRKGPELPLVPVKRQRHELLLGAGSGPGAGQQQATPGALLQAGPPRCSSLQAPIM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 LLSGHEGEVYCCKFHPNGSTLASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHYNTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LLSGHEGEVYCCKFHPNGSTLASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHYNTD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 GSMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 GSMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 IRKKAAIQTFQNTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHADSVTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 IRKKAAIQTFQNTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHADSVTG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 LSLSSEGSYLLSNAMDNTVRVWDVRPFAPKERCVKIFQGNVHNFEKNLLRCSWSPDGSKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LSLSSEGSYLLSNAMDNTVRVWDVRPFAPKERCVKIFQGNVHNFEKNLLRCSWSPDGSKI
250 260 270 280 290 300
310 320 330 340 350
pF1KE5 AAGSADRFVYVWDTTSRRILYKLPGHAGSINEVAFHPDEPIIISASSDKRLYMGEIQ
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 AAGSADRFVYVWDTTSRRILYKLPGHAGSINEVAFHPDEPIIISASSDKRLYMGEIQ
310 320 330 340 350
>>XP_005246141 (OMIM: 610767,611081) PREDICTED: autophag (480 aa)
initn: 383 init1: 131 opt: 482 Z-score: 396.5 bits: 82.3 E(85289): 2.4e-15
Smith-Waterman score: 482; 29.6% identity (63.2% similar) in 334 aa overlap (25-344:146-467)
10 20 30 40
pF1KE5 MIEQQKRKGPELPLVPVKRQRHELLLGAGSGPGAGQQQAT-----PGALLQAGP
::: :. :...... : ... :
XP_005 ISRAATKRLSQPAGGLLDSITNIFGLSESPLLGHHSSSDAARRRSVSSFPVPQDNVDTHP
120 130 140 150 160 170
50 60 70 80 90 100
pF1KE5 PRCSSLQAP---IMLLSGHEGEVYCCKFHPNGSTLASAGFDRLILLWNVYGD-CDNYATL
. ...: . ....:.::: .: :.. ::..:.:: . ::.:.:. :. ..:
XP_005 GSGKEVRVPATALCVFDAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSL
180 190 200 210 220 230
110 120 130 140 150 160
pF1KE5 KGHSGAVMELHYNTDGSMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQ
.: .... ..... ::.:..::.: . .: . . . : ::.. : : . .
XP_005 SGSNAGITSIEFDSAGSYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNAR
240 250 260 270 280 290
170 180 190 200 210 220
pF1KE5 LVCTGSDDGTVKLWDIRKKAAIQT-FQNTYQVLAVTFND---TSDQIISGGIDNDIKVWD
.: .:: : :.::::.:.:. :.: : .. . :: : . ..:: .:. :. ::
XP_005 IV-SGSHDRTLKLWDLRSKVCIKTVFAGS------SCNDIVCTEQCVMSGHFDKKIRFWD
300 310 320 330 340
230 240 250 260 270 280
pF1KE5 LRQNKLTYTMRGHADSVTGLSLSSEGSYLLSNAMDNTVRVWDVRPFAPKERCVKIFQGNV
.:..... :. ..:.:.:. : . ::: . :. ..: :.: : : . :..
XP_005 IRSESIVREME-LLGKITALDLNPERTELLSCSRDDLLKVIDLRTNAIK----QTFSAPG
350 360 370 380 390 400
290 300 310 320 330 340
pF1KE5 HNFEKNLLRCSWSPDGSKIAAGSADRFVYVWDTTSRRILYKLPG-HAGSINEVAFHPDEP
. .. : .::::: .:::::. .:.:.. . .. : :..::: ::. :.
XP_005 FKCGSDWTRVVFSPDGSYVAAGSAEGSLYIWSVLTGKVEKVLSKQHSSSINAVAWSPSGS
410 420 430 440 450 460
350
pF1KE5 IIISASSDKRLYMGEIQ
..:
XP_005 HVVSVDKGCKAVLWAQY
470 480
>>XP_006712671 (OMIM: 610767,611081) PREDICTED: autophag (540 aa)
initn: 383 init1: 131 opt: 482 Z-score: 395.9 bits: 82.4 E(85289): 2.6e-15
Smith-Waterman score: 482; 29.6% identity (63.2% similar) in 334 aa overlap (25-344:206-527)
10 20 30 40
pF1KE5 MIEQQKRKGPELPLVPVKRQRHELLLGAGSGPGAGQQQAT-----PGALLQAGP
::: :. :...... : ... :
XP_006 ISRAATKRLSQPAGGLLDSITNIFGLSESPLLGHHSSSDAARRRSVSSFPVPQDNVDTHP
180 190 200 210 220 230
50 60 70 80 90 100
pF1KE5 PRCSSLQAP---IMLLSGHEGEVYCCKFHPNGSTLASAGFDRLILLWNVYGD-CDNYATL
. ...: . ....:.::: .: :.. ::..:.:: . ::.:.:. :. ..:
XP_006 GSGKEVRVPATALCVFDAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSL
240 250 260 270 280 290
110 120 130 140 150 160
pF1KE5 KGHSGAVMELHYNTDGSMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQ
.: .... ..... ::.:..::.: . .: . . . : ::.. : : . .
XP_006 SGSNAGITSIEFDSAGSYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNAR
300 310 320 330 340 350
170 180 190 200 210 220
pF1KE5 LVCTGSDDGTVKLWDIRKKAAIQT-FQNTYQVLAVTFND---TSDQIISGGIDNDIKVWD
.: .:: : :.::::.:.:. :.: : .. . :: : . ..:: .:. :. ::
XP_006 IV-SGSHDRTLKLWDLRSKVCIKTVFAGS------SCNDIVCTEQCVMSGHFDKKIRFWD
360 370 380 390 400
230 240 250 260 270 280
pF1KE5 LRQNKLTYTMRGHADSVTGLSLSSEGSYLLSNAMDNTVRVWDVRPFAPKERCVKIFQGNV
.:..... :. ..:.:.:. : . ::: . :. ..: :.: : : . :..
XP_006 IRSESIVREME-LLGKITALDLNPERTELLSCSRDDLLKVIDLRTNAIK----QTFSAPG
410 420 430 440 450 460
290 300 310 320 330 340
pF1KE5 HNFEKNLLRCSWSPDGSKIAAGSADRFVYVWDTTSRRILYKLPG-HAGSINEVAFHPDEP
. .. : .::::: .:::::. .:.:.. . .. : :..::: ::. :.
XP_006 FKCGSDWTRVVFSPDGSYVAAGSAEGSLYIWSVLTGKVEKVLSKQHSSSINAVAWSPSGS
470 480 490 500 510 520
350
pF1KE5 IIISASSDKRLYMGEIQ
..:
XP_006 HVVSVDKGCKAVLWAQY
530 540
>>XP_005246139 (OMIM: 610767,611081) PREDICTED: autophag (624 aa)
initn: 383 init1: 131 opt: 482 Z-score: 395.2 bits: 82.5 E(85289): 2.8e-15
Smith-Waterman score: 482; 29.6% identity (63.2% similar) in 334 aa overlap (25-344:290-611)
10 20 30 40
pF1KE5 MIEQQKRKGPELPLVPVKRQRHELLLGAGSGPGAGQQQAT-----PGALLQAGP
::: :. :...... : ... :
XP_005 ISRAATKRLSQPAGGLLDSITNIFGLSESPLLGHHSSSDAARRRSVSSFPVPQDNVDTHP
260 270 280 290 300 310
50 60 70 80 90 100
pF1KE5 PRCSSLQAP---IMLLSGHEGEVYCCKFHPNGSTLASAGFDRLILLWNVYGD-CDNYATL
. ...: . ....:.::: .: :.. ::..:.:: . ::.:.:. :. ..:
XP_005 GSGKEVRVPATALCVFDAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSL
320 330 340 350 360 370
110 120 130 140 150 160
pF1KE5 KGHSGAVMELHYNTDGSMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQ
.: .... ..... ::.:..::.: . .: . . . : ::.. : : . .
XP_005 SGSNAGITSIEFDSAGSYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNAR
380 390 400 410 420 430
170 180 190 200 210 220
pF1KE5 LVCTGSDDGTVKLWDIRKKAAIQT-FQNTYQVLAVTFND---TSDQIISGGIDNDIKVWD
.: .:: : :.::::.:.:. :.: : .. . :: : . ..:: .:. :. ::
XP_005 IV-SGSHDRTLKLWDLRSKVCIKTVFAGS------SCNDIVCTEQCVMSGHFDKKIRFWD
440 450 460 470 480 490
230 240 250 260 270 280
pF1KE5 LRQNKLTYTMRGHADSVTGLSLSSEGSYLLSNAMDNTVRVWDVRPFAPKERCVKIFQGNV
.:..... :. ..:.:.:. : . ::: . :. ..: :.: : : . :..
XP_005 IRSESIVREME-LLGKITALDLNPERTELLSCSRDDLLKVIDLRTNAIK----QTFSAPG
500 510 520 530 540
290 300 310 320 330 340
pF1KE5 HNFEKNLLRCSWSPDGSKIAAGSADRFVYVWDTTSRRILYKLPG-HAGSINEVAFHPDEP
. .. : .::::: .:::::. .:.:.. . .. : :..::: ::. :.
XP_005 FKCGSDWTRVVFSPDGSYVAAGSAEGSLYIWSVLTGKVEKVLSKQHSSSINAVAWSPSGS
550 560 570 580 590 600
350
pF1KE5 IIISASSDKRLYMGEIQ
..:
XP_005 HVVSVDKGCKAVLWAQY
610 620
>>NP_942593 (OMIM: 610767,611081) autophagy-related prot (444 aa)
initn: 383 init1: 131 opt: 476 Z-score: 392.1 bits: 81.4 E(85289): 4.2e-15
Smith-Waterman score: 480; 30.7% identity (62.7% similar) in 319 aa overlap (32-344:139-431)
10 20 30 40 50 60
pF1KE5 IEQQKRKGPELPLVPVKRQRHELLLGAGSGPGAGQQQATPGALLQAGPPRCSSLQAPIML
::.:.. .:.. : : .
NP_942 ETSPVRAISRAATRRSVSSFPVPQDNVDTHPGSGKEVRVPATAL------C--------V
110 120 130 140 150
70 80 90 100 110 120
pF1KE5 LSGHEGEVYCCKFHPNGSTLASAGFDRLILLWNVYGD-CDNYATLKGHSGAVMELHYNTD
...:.::: .: :.. ::..:.:: . ::.:.:. :. ..:.: .... .....
NP_942 FDAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSA
160 170 180 190 200 210
130 140 150 160 170 180
pF1KE5 GSMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWD
::.:..::.: . .: . . . : ::.. : : . ..: .:: : :.::::
NP_942 GSYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIV-SGSHDRTLKLWD
220 230 240 250 260 270
190 200 210 220 230
pF1KE5 IRKKAAIQTFQNTYQVLA-VTFND---TSDQIISGGIDNDIKVWDLRQNKLTYTMRGHAD
.:.:. :.: :.: . :: : . ..:: .:. :. ::.:..... :.
NP_942 LRSKVCIKT------VFAGSSCNDIVCTEQCVMSGHFDKKIRFWDIRSESIVREME-LLG
280 290 300 310 320
240 250 260 270 280 290
pF1KE5 SVTGLSLSSEGSYLLSNAMDNTVRVWDVRPFAPKERCVKIFQGNVHNFEKNLLRCSWSPD
..:.:.:. : . ::: . :. ..: :.: : : . :.. . .. : .:::
NP_942 KITALDLNPERTELLSCSRDDLLKVIDLRTNAIK----QTFSAPGFKCGSDWTRVVFSPD
330 340 350 360 370 380
300 310 320 330 340 350
pF1KE5 GSKIAAGSADRFVYVWDTTSRRILYKLPG-HAGSINEVAFHPDEPIIISASSDKRLYMGE
:: .:::::. .:.:.. . .. : :..::: ::. :. ..:
NP_942 GSYVAAGSAEGSLYIWSVLTGKVEKVLSKQHSSSINAVAWSPSGSHVVSVDKGCKAVLWA
390 400 410 420 430 440
pF1KE5 IQ
NP_942 QY
>>XP_005246143 (OMIM: 610767,611081) PREDICTED: autophag (463 aa)
initn: 383 init1: 131 opt: 476 Z-score: 391.9 bits: 81.4 E(85289): 4.3e-15
Smith-Waterman score: 480; 30.7% identity (62.7% similar) in 319 aa overlap (32-344:158-450)
10 20 30 40 50 60
pF1KE5 IEQQKRKGPELPLVPVKRQRHELLLGAGSGPGAGQQQATPGALLQAGPPRCSSLQAPIML
::.:.. .:.. : : .
XP_005 AGGLLDSITNIFGRRSVSSFPVPQDNVDTHPGSGKEVRVPATAL------C--------V
130 140 150 160 170
70 80 90 100 110 120
pF1KE5 LSGHEGEVYCCKFHPNGSTLASAGFDRLILLWNVYGD-CDNYATLKGHSGAVMELHYNTD
...:.::: .: :.. ::..:.:: . ::.:.:. :. ..:.: .... .....
XP_005 FDAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSA
180 190 200 210 220 230
130 140 150 160 170 180
pF1KE5 GSMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWD
::.:..::.: . .: . . . : ::.. : : . ..: .:: : :.::::
XP_005 GSYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIV-SGSHDRTLKLWD
240 250 260 270 280 290
190 200 210 220 230
pF1KE5 IRKKAAIQTFQNTYQVLA-VTFND---TSDQIISGGIDNDIKVWDLRQNKLTYTMRGHAD
.:.:. :.: :.: . :: : . ..:: .:. :. ::.:..... :.
XP_005 LRSKVCIKT------VFAGSSCNDIVCTEQCVMSGHFDKKIRFWDIRSESIVREME-LLG
300 310 320 330 340
240 250 260 270 280 290
pF1KE5 SVTGLSLSSEGSYLLSNAMDNTVRVWDVRPFAPKERCVKIFQGNVHNFEKNLLRCSWSPD
..:.:.:. : . ::: . :. ..: :.: : : . :.. . .. : .:::
XP_005 KITALDLNPERTELLSCSRDDLLKVIDLRTNAIK----QTFSAPGFKCGSDWTRVVFSPD
350 360 370 380 390 400
300 310 320 330 340 350
pF1KE5 GSKIAAGSADRFVYVWDTTSRRILYKLPG-HAGSINEVAFHPDEPIIISASSDKRLYMGE
:: .:::::. .:.:.. . .. : :..::: ::. :. ..:
XP_005 GSYVAAGSAEGSLYIWSVLTGKVEKVLSKQHSSSINAVAWSPSGSHVVSVDKGCKAVLWA
410 420 430 440 450 460
pF1KE5 IQ
XP_005 QY
>>NP_001177196 (OMIM: 610767,611081) autophagy-related p (491 aa)
initn: 383 init1: 131 opt: 476 Z-score: 391.6 bits: 81.5 E(85289): 4.5e-15
Smith-Waterman score: 480; 30.7% identity (62.7% similar) in 319 aa overlap (32-344:186-478)
10 20 30 40 50 60
pF1KE5 IEQQKRKGPELPLVPVKRQRHELLLGAGSGPGAGQQQATPGALLQAGPPRCSSLQAPIML
::.:.. .:.. : : .
NP_001 AGGLLDSITNIFGRRSVSSFPVPQDNVDTHPGSGKEVRVPATAL------C--------V
160 170 180 190 200
70 80 90 100 110 120
pF1KE5 LSGHEGEVYCCKFHPNGSTLASAGFDRLILLWNVYGD-CDNYATLKGHSGAVMELHYNTD
...:.::: .: :.. ::..:.:: . ::.:.:. :. ..:.: .... .....
NP_001 FDAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSA
210 220 230 240 250 260
130 140 150 160 170 180
pF1KE5 GSMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWD
::.:..::.: . .: . . . : ::.. : : . ..: .:: : :.::::
NP_001 GSYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIV-SGSHDRTLKLWD
270 280 290 300 310 320
190 200 210 220 230
pF1KE5 IRKKAAIQTFQNTYQVLA-VTFND---TSDQIISGGIDNDIKVWDLRQNKLTYTMRGHAD
.:.:. :.: :.: . :: : . ..:: .:. :. ::.:..... :.
NP_001 LRSKVCIKT------VFAGSSCNDIVCTEQCVMSGHFDKKIRFWDIRSESIVREME-LLG
330 340 350 360 370
240 250 260 270 280 290
pF1KE5 SVTGLSLSSEGSYLLSNAMDNTVRVWDVRPFAPKERCVKIFQGNVHNFEKNLLRCSWSPD
..:.:.:. : . ::: . :. ..: :.: : : . :.. . .. : .:::
NP_001 KITALDLNPERTELLSCSRDDLLKVIDLRTNAIK----QTFSAPGFKCGSDWTRVVFSPD
380 390 400 410 420
300 310 320 330 340 350
pF1KE5 GSKIAAGSADRFVYVWDTTSRRILYKLPG-HAGSINEVAFHPDEPIIISASSDKRLYMGE
:: .:::::. .:.:.. . .. : :..::: ::. :. ..:
NP_001 GSYVAAGSAEGSLYIWSVLTGKVEKVLSKQHSSSINAVAWSPSGSHVVSVDKGCKAVLWA
430 440 450 460 470 480
pF1KE5 IQ
NP_001 QY
490
>>NP_001177195 (OMIM: 610767,611081) autophagy-related p (523 aa)
initn: 383 init1: 131 opt: 476 Z-score: 391.3 bits: 81.5 E(85289): 4.6e-15
Smith-Waterman score: 480; 30.7% identity (62.7% similar) in 319 aa overlap (32-344:218-510)
10 20 30 40 50 60
pF1KE5 IEQQKRKGPELPLVPVKRQRHELLLGAGSGPGAGQQQATPGALLQAGPPRCSSLQAPIML
::.:.. .:.. : : .
NP_001 AGGLLDSITNIFGRRSVSSFPVPQDNVDTHPGSGKEVRVPATAL------C--------V
190 200 210 220 230
70 80 90 100 110 120
pF1KE5 LSGHEGEVYCCKFHPNGSTLASAGFDRLILLWNVYGD-CDNYATLKGHSGAVMELHYNTD
...:.::: .: :.. ::..:.:: . ::.:.:. :. ..:.: .... .....
NP_001 FDAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSA
240 250 260 270 280 290
130 140 150 160 170 180
pF1KE5 GSMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWD
::.:..::.: . .: . . . : ::.. : : . ..: .:: : :.::::
NP_001 GSYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIV-SGSHDRTLKLWD
300 310 320 330 340 350
190 200 210 220 230
pF1KE5 IRKKAAIQTFQNTYQVLA-VTFND---TSDQIISGGIDNDIKVWDLRQNKLTYTMRGHAD
.:.:. :.: :.: . :: : . ..:: .:. :. ::.:..... :.
NP_001 LRSKVCIKT------VFAGSSCNDIVCTEQCVMSGHFDKKIRFWDIRSESIVREME-LLG
360 370 380 390 400
240 250 260 270 280 290
pF1KE5 SVTGLSLSSEGSYLLSNAMDNTVRVWDVRPFAPKERCVKIFQGNVHNFEKNLLRCSWSPD
..:.:.:. : . ::: . :. ..: :.: : : . :.. . .. : .:::
NP_001 KITALDLNPERTELLSCSRDDLLKVIDLRTNAIK----QTFSAPGFKCGSDWTRVVFSPD
410 420 430 440 450 460
300 310 320 330 340 350
pF1KE5 GSKIAAGSADRFVYVWDTTSRRILYKLPG-HAGSINEVAFHPDEPIIISASSDKRLYMGE
:: .:::::. .:.:.. . .. : :..::: ::. :. ..:
NP_001 GSYVAAGSAEGSLYIWSVLTGKVEKVLSKQHSSSINAVAWSPSGSHVVSVDKGCKAVLWA
470 480 490 500 510 520
pF1KE5 IQ
NP_001 QY
>>NP_060444 (OMIM: 610767,611081) autophagy-related prot (588 aa)
initn: 383 init1: 131 opt: 476 Z-score: 390.8 bits: 81.6 E(85289): 5e-15
Smith-Waterman score: 480; 30.7% identity (62.7% similar) in 319 aa overlap (32-344:283-575)
10 20 30 40 50 60
pF1KE5 IEQQKRKGPELPLVPVKRQRHELLLGAGSGPGAGQQQATPGALLQAGPPRCSSLQAPIML
::.:.. .:.. : : .
NP_060 ETSPVRAISRAATRRSVSSFPVPQDNVDTHPGSGKEVRVPATAL------C--------V
260 270 280 290
70 80 90 100 110 120
pF1KE5 LSGHEGEVYCCKFHPNGSTLASAGFDRLILLWNVYGD-CDNYATLKGHSGAVMELHYNTD
...:.::: .: :.. ::..:.:: . ::.:.:. :. ..:.: .... .....
NP_060 FDAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSA
300 310 320 330 340 350
130 140 150 160 170 180
pF1KE5 GSMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWD
::.:..::.: . .: . . . : ::.. : : . ..: .:: : :.::::
NP_060 GSYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIV-SGSHDRTLKLWD
360 370 380 390 400 410
190 200 210 220 230
pF1KE5 IRKKAAIQTFQNTYQVLA-VTFND---TSDQIISGGIDNDIKVWDLRQNKLTYTMRGHAD
.:.:. :.: :.: . :: : . ..:: .:. :. ::.:..... :.
NP_060 LRSKVCIKT------VFAGSSCNDIVCTEQCVMSGHFDKKIRFWDIRSESIVREME-LLG
420 430 440 450 460 470
240 250 260 270 280 290
pF1KE5 SVTGLSLSSEGSYLLSNAMDNTVRVWDVRPFAPKERCVKIFQGNVHNFEKNLLRCSWSPD
..:.:.:. : . ::: . :. ..: :.: : : . :.. . .. : .:::
NP_060 KITALDLNPERTELLSCSRDDLLKVIDLRTNAIK----QTFSAPGFKCGSDWTRVVFSPD
480 490 500 510 520
300 310 320 330 340 350
pF1KE5 GSKIAAGSADRFVYVWDTTSRRILYKLPG-HAGSINEVAFHPDEPIIISASSDKRLYMGE
:: .:::::. .:.:.. . .. : :..::: ::. :. ..:
NP_060 GSYVAAGSAEGSLYIWSVLTGKVEKVLSKQHSSSINAVAWSPSGSHVVSVDKGCKAVLWA
530 540 550 560 570 580
pF1KE5 IQ
NP_060 QY
>>NP_110430 (OMIM: 610767,611081) autophagy-related prot (607 aa)
initn: 383 init1: 131 opt: 476 Z-score: 390.7 bits: 81.6 E(85289): 5.1e-15
Smith-Waterman score: 480; 30.7% identity (62.7% similar) in 319 aa overlap (32-344:302-594)
10 20 30 40 50 60
pF1KE5 IEQQKRKGPELPLVPVKRQRHELLLGAGSGPGAGQQQATPGALLQAGPPRCSSLQAPIML
::.:.. .:.. : : .
NP_110 AGGLLDSITNIFGRRSVSSFPVPQDNVDTHPGSGKEVRVPATAL------C--------V
280 290 300 310
70 80 90 100 110 120
pF1KE5 LSGHEGEVYCCKFHPNGSTLASAGFDRLILLWNVYGD-CDNYATLKGHSGAVMELHYNTD
...:.::: .: :.. ::..:.:: . ::.:.:. :. ..:.: .... .....
NP_110 FDAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSA
320 330 340 350 360 370
130 140 150 160 170 180
pF1KE5 GSMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWD
::.:..::.: . .: . . . : ::.. : : . ..: .:: : :.::::
NP_110 GSYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIV-SGSHDRTLKLWD
380 390 400 410 420 430
190 200 210 220 230
pF1KE5 IRKKAAIQTFQNTYQVLA-VTFND---TSDQIISGGIDNDIKVWDLRQNKLTYTMRGHAD
.:.:. :.: :.: . :: : . ..:: .:. :. ::.:..... :.
NP_110 LRSKVCIKT------VFAGSSCNDIVCTEQCVMSGHFDKKIRFWDIRSESIVREME-LLG
440 450 460 470 480
240 250 260 270 280 290
pF1KE5 SVTGLSLSSEGSYLLSNAMDNTVRVWDVRPFAPKERCVKIFQGNVHNFEKNLLRCSWSPD
..:.:.:. : . ::: . :. ..: :.: : : . :.. . .. : .:::
NP_110 KITALDLNPERTELLSCSRDDLLKVIDLRTNAIK----QTFSAPGFKCGSDWTRVVFSPD
490 500 510 520 530 540
300 310 320 330 340 350
pF1KE5 GSKIAAGSADRFVYVWDTTSRRILYKLPG-HAGSINEVAFHPDEPIIISASSDKRLYMGE
:: .:::::. .:.:.. . .. : :..::: ::. :. ..:
NP_110 GSYVAAGSAEGSLYIWSVLTGKVEKVLSKQHSSSINAVAWSPSGSHVVSVDKGCKAVLWA
550 560 570 580 590 600
pF1KE5 IQ
NP_110 QY
357 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 00:25:45 2016 done: Tue Nov 8 00:25:47 2016
Total Scan time: 6.560 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]