Result of FASTA (omim) for
pFN21AE5405
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5405, 332 aa
1>>>pF1KE5405 332 - 332 aa - 332 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.3026+/-0.000352; mu= 16.8169+/- 0.022
mean_var=83.2743+/-17.403, 0's: 0 Z-trim(116.2): 66 B-trim: 589 in 1/56
Lambda= 0.140546
statistics sampled from 27044 (27146) to 27044 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.682), E-opt: 0.2 (0.318), width: 16
Scan time: 5.860
The best scores are: opt bits E(85289)
NP_113648 (OMIM: 607370) potassium channel subfami ( 332) 2293 474.5 1.3e-133
NP_001128583 (OMIM: 607370) potassium channel subf ( 271) 1532 320.1 3.3e-87
NP_115491 (OMIM: 607369) potassium channel subfami ( 309) 768 165.3 1.5e-40
NP_001128578 (OMIM: 607369) potassium channel subf ( 294) 763 164.2 3e-40
NP_001128579 (OMIM: 607369) potassium channel subf ( 262) 645 140.3 4.4e-33
XP_016866835 (OMIM: 607369) PREDICTED: potassium c ( 262) 645 140.3 4.4e-33
NP_001128577 (OMIM: 607369) potassium channel subf ( 322) 643 139.9 6.8e-33
XP_005249513 (OMIM: 603493) PREDICTED: potassium c ( 496) 594 130.2 9.2e-30
NP_003731 (OMIM: 603493) potassium channel subfami ( 499) 590 129.4 1.6e-29
NP_201567 (OMIM: 605720) potassium channel subfami ( 393) 576 126.4 9.7e-29
NP_001304019 (OMIM: 605720) potassium channel subf ( 393) 576 126.4 9.7e-29
NP_066984 (OMIM: 605873) potassium channel subfami ( 538) 515 114.2 6.5e-25
XP_011507824 (OMIM: 603219) PREDICTED: potassium c ( 370) 513 113.6 6.5e-25
XP_011507826 (OMIM: 603219) PREDICTED: potassium c ( 370) 513 113.6 6.5e-25
XP_011507825 (OMIM: 603219) PREDICTED: potassium c ( 370) 513 113.6 6.5e-25
NP_612191 (OMIM: 605873) potassium channel subfami ( 543) 515 114.2 6.5e-25
NP_612190 (OMIM: 605873) potassium channel subfami ( 543) 515 114.2 6.5e-25
NP_055032 (OMIM: 603219) potassium channel subfami ( 411) 513 113.7 7e-25
XP_016856738 (OMIM: 603219) PREDICTED: potassium c ( 412) 513 113.7 7e-25
XP_016856737 (OMIM: 603219) PREDICTED: potassium c ( 422) 513 113.7 7.1e-25
NP_001017424 (OMIM: 603219) potassium channel subf ( 422) 513 113.7 7.1e-25
NP_001017425 (OMIM: 603219) potassium channel subf ( 426) 513 113.7 7.2e-25
XP_011513237 (OMIM: 607369) PREDICTED: potassium c ( 197) 496 110.0 4.4e-24
NP_004814 (OMIM: 603939) potassium channel subfami ( 313) 481 107.1 5.1e-23
XP_011535142 (OMIM: 605873) PREDICTED: potassium c ( 410) 438 98.5 2.6e-20
NP_002236 (OMIM: 601745) potassium channel subfami ( 336) 417 94.1 4.4e-19
NP_071753 (OMIM: 607368) potassium channel subfami ( 330) 354 81.4 3e-15
NP_002237 (OMIM: 603220,615344) potassium channel ( 394) 344 79.4 1.4e-14
NP_001269463 (OMIM: 605874,612292) potassium chann ( 374) 339 78.4 2.7e-14
XP_011515404 (OMIM: 605874,612292) PREDICTED: pota ( 374) 339 78.4 2.7e-14
XP_011515403 (OMIM: 605874,612292) PREDICTED: pota ( 401) 339 78.4 2.9e-14
NP_203133 (OMIM: 603940) potassium channel subfami ( 307) 330 76.5 8.3e-14
NP_258416 (OMIM: 603940) potassium channel subfami ( 252) 318 74.0 3.9e-13
NP_203134 (OMIM: 603940) potassium channel subfami ( 252) 318 74.0 3.9e-13
NP_005705 (OMIM: 603940) potassium channel subfami ( 257) 315 73.4 6e-13
XP_011542486 (OMIM: 601745) PREDICTED: potassium c ( 268) 269 64.0 4e-10
XP_006715298 (OMIM: 603493) PREDICTED: potassium c ( 317) 265 63.3 7.9e-10
XP_011525828 (OMIM: 603939) PREDICTED: potassium c ( 179) 248 59.6 5.6e-09
XP_005264350 (OMIM: 603220,615344) PREDICTED: pota ( 284) 206 51.3 2.9e-06
XP_016869020 (OMIM: 605874,612292) PREDICTED: pota ( 264) 199 49.8 7.4e-06
XP_016869019 (OMIM: 605874,612292) PREDICTED: pota ( 264) 199 49.8 7.4e-06
XP_011515405 (OMIM: 605874,612292) PREDICTED: pota ( 291) 199 49.9 7.9e-06
NP_071337 (OMIM: 607367) potassium channel subfami ( 408) 194 49.0 2.1e-05
NP_862823 (OMIM: 613655,613656) potassium channel ( 384) 186 47.4 6.1e-05
NP_071338 (OMIM: 607366) potassium channel subfami ( 430) 179 46.0 0.00018
XP_011525829 (OMIM: 603939) PREDICTED: potassium c ( 176) 164 42.6 0.00075
XP_016882995 (OMIM: 603939) PREDICTED: potassium c ( 185) 164 42.6 0.00077
>>NP_113648 (OMIM: 607370) potassium channel subfamily K (332 aa)
initn: 2293 init1: 2293 opt: 2293 Z-score: 2519.5 bits: 474.5 E(85289): 1.3e-133
Smith-Waterman score: 2293; 99.7% identity (100.0% similar) in 332 aa overlap (1-332:1-332)
10 20 30 40 50 60
pF1KE5 MYRPRARAAPEGRVRGCAVPGTVLLLLAYLAYLALGTGVFWTLEGRAAQDSSRSFQRDKW
::::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::
NP_113 MYRPRARAAPEGRVRGCAVPSTVLLLLAYLAYLALGTGVFWTLEGRAAQDSSRSFQRDKW
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 ELLQNFTCLDRPALDSLIRDVVQAYKNGASLLSNTTSMGRWELVGSFFFSVSTITTIGYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_113 ELLQNFTCLDRPALDSLIRDVVQAYKNGASLLSNTTSMGRWELVGSFFFSVSTITTIGYG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 NLSPNTMAARLFCIFFALVGIPLNLVVLNRLGHLMQQGVNHWASRLGGTWQDPDKARWLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_113 NLSPNTMAARLFCIFFALVGIPLNLVVLNRLGHLMQQGVNHWASRLGGTWQDPDKARWLA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 GSGALLSGLLLFLLLPPLLFSHMEGWSYTEGFYFAFITLSTVGFGDYVIGMNPSQRYPLW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_113 GSGALLSGLLLFLLLPPLLFSHMEGWSYTEGFYFAFITLSTVGFGDYVIGMNPSQRYPLW
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 YKNMVSLWILFGMAWLALIIKLILSQLETPGRVCSCCHHSSKEDFKSQSWRQGPDREPES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_113 YKNMVSLWILFGMAWLALIIKLILSQLETPGRVCSCCHHSSKEDFKSQSWRQGPDREPES
250 260 270 280 290 300
310 320 330
pF1KE5 HSPQQGCYPEGPMGIIQHLEPSAHAAGCGKDS
::::::::::::::::::::::::::::::::
NP_113 HSPQQGCYPEGPMGIIQHLEPSAHAAGCGKDS
310 320 330
>>NP_001128583 (OMIM: 607370) potassium channel subfamil (271 aa)
initn: 1532 init1: 1532 opt: 1532 Z-score: 1686.8 bits: 320.1 E(85289): 3.3e-87
Smith-Waterman score: 1532; 99.6% identity (100.0% similar) in 229 aa overlap (1-229:1-229)
10 20 30 40 50 60
pF1KE5 MYRPRARAAPEGRVRGCAVPGTVLLLLAYLAYLALGTGVFWTLEGRAAQDSSRSFQRDKW
::::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::
NP_001 MYRPRARAAPEGRVRGCAVPSTVLLLLAYLAYLALGTGVFWTLEGRAAQDSSRSFQRDKW
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 ELLQNFTCLDRPALDSLIRDVVQAYKNGASLLSNTTSMGRWELVGSFFFSVSTITTIGYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELLQNFTCLDRPALDSLIRDVVQAYKNGASLLSNTTSMGRWELVGSFFFSVSTITTIGYG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 NLSPNTMAARLFCIFFALVGIPLNLVVLNRLGHLMQQGVNHWASRLGGTWQDPDKARWLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NLSPNTMAARLFCIFFALVGIPLNLVVLNRLGHLMQQGVNHWASRLGGTWQDPDKARWLA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 GSGALLSGLLLFLLLPPLLFSHMEGWSYTEGFYFAFITLSTVGFGDYVIGMNPSQRYPLW
:::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSGALLSGLLLFLLLPPLLFSHMEGWSYTEGFYFAFITLSTVGFGDYVIASCLISDTRKP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 YKNMVSLWILFGMAWLALIIKLILSQLETPGRVCSCCHHSSKEDFKSQSWRQGPDREPES
NP_001 NRDWQTLERTSKSSGGLLKYRFLAGHGGSHL
250 260 270
>>NP_115491 (OMIM: 607369) potassium channel subfamily K (309 aa)
initn: 757 init1: 406 opt: 768 Z-score: 848.8 bits: 165.3 E(85289): 1.5e-40
Smith-Waterman score: 768; 42.5% identity (73.5% similar) in 287 aa overlap (21-302:12-287)
10 20 30 40 50
pF1KE5 MYRPRARAAPEGRVRGCAVPGTVL-LLLAYLAYLALGTGVFWTLEGRAAQDSSRSFQRDK
: :: :::::. :: ::. .: :: .: .: .:: .:
NP_115 MPSAGLCSCWGGRVLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEK
10 20 30 40 50
60 70 80 90 100 110
pF1KE5 WELLQNFTCLDRPALDSLIRDVVQAYKNGASLLSNTTSMGRWELVGSFFFSVSTITTIGY
..:.:.::::. :...... ...:. .:.. .:.:. . :.. .::::. ...:::::
NP_115 LRFLENYTCLDQWAMEQFVQVIMEAWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGY
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE5 GNLSPNTMAARLFCIFFALVGIPLNLVVLNRLGHLMQQGVNHWASRLGGTWQD-PDKARW
:::.:.: :...::.:.::.:::::.. ::.:: .. : :. :.: : ...
NP_115 GNLAPSTEAGQVFCVFYALLGIPLNVIFLNHLGTGLRA---HLAAI--ERWEDRPRRSQV
120 130 140 150 160
180 190 200 210 220 230
pF1KE5 LA--GSGALLS-GLLLFLLLPPLLFSHMEGWSYTEGFYFAFITLSTVGFGDYVIGMNPSQ
: : . .:. : :..:..::..:::.::::..::::::::::::.::::::.: .::.
NP_115 LQVLGLALFLTLGTLVILIFPPMVFSHVEGWSFSEGFYFAFITLSTIGFGDYVVGTDPSK
170 180 190 200 210 220
240 250 260 270 280 290
pF1KE5 RYPLWYKNMVSLWILFGMAWLALIIKLILSQLETPGRVCSCCHHSSKEDFKSQSWRQGPD
.: :......:::.:.::::::. : : . ::. .. . . .:
NP_115 HYISVYRSLAAIWILLGLAWLALILPL------GPLLLHRCCQLWLLSLRQGCGAKAAPG
230 240 250 260 270 280
300 310 320 330
pF1KE5 REPESHSPQQGCYPEGPMGIIQHLEPSAHAAGCGKDS
:.:. :
NP_115 RRPRRGSTAARGVQVTPQDFPISKKGLGS
290 300
>>NP_001128578 (OMIM: 607369) potassium channel subfamil (294 aa)
initn: 757 init1: 406 opt: 763 Z-score: 843.6 bits: 164.2 E(85289): 3e-40
Smith-Waterman score: 763; 44.9% identity (76.0% similar) in 263 aa overlap (21-278:12-263)
10 20 30 40 50
pF1KE5 MYRPRARAAPEGRVRGCAVPGTVL-LLLAYLAYLALGTGVFWTLEGRAAQDSSRSFQRDK
: :: :::::. :: ::. .: :: .: .: .:: .:
NP_001 MPSAGLCSCWGGRVLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEK
10 20 30 40 50
60 70 80 90 100 110
pF1KE5 WELLQNFTCLDRPALDSLIRDVVQAYKNGASLLSNTTSMGRWELVGSFFFSVSTITTIGY
..:.:.::::. :...... ...:. .:.. .:.:. . :.. .::::. ...:::::
NP_001 LRFLENYTCLDQWAMEQFVQVIMEAWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGY
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE5 GNLSPNTMAARLFCIFFALVGIPLNLVVLNRLGHLMQQGVNHWASRLGGTWQD-PDKARW
:::.:.: :...::.:.::.:::::.. ::.:: .. : :. :.: : ...
NP_001 GNLAPSTEAGQVFCVFYALLGIPLNVIFLNHLGTGLRA---HLAAI--ERWEDRPRRSQV
120 130 140 150 160
180 190 200 210 220 230
pF1KE5 LA--GSGALLS-GLLLFLLLPPLLFSHMEGWSYTEGFYFAFITLSTVGFGDYVIGMNPSQ
: : . .:. : :..:..::..:::.::::..::::::::::::.::::::.: .::.
NP_001 LQVLGLALFLTLGTLVILIFPPMVFSHVEGWSFSEGFYFAFITLSTIGFGDYVVGTDPSK
170 180 190 200 210 220
240 250 260 270 280 290
pF1KE5 RYPLWYKNMVSLWILFGMAWLALIIKLILSQLETPGRVCSCCHHSSKEDFKSQSWRQGPD
.: :......:::.:.::::::. : : . ::.
NP_001 HYISVYRSLAAIWILLGLAWLALILPL------GPLLLHRCCQLWLLSRGLGVKDGAASD
230 240 250 260 270 280
300 310 320 330
pF1KE5 REPESHSPQQGCYPEGPMGIIQHLEPSAHAAGCGKDS
NP_001 PSGLPRPQKIPISA
290
>>NP_001128579 (OMIM: 607369) potassium channel subfamil (262 aa)
initn: 642 init1: 406 opt: 645 Z-score: 715.0 bits: 140.3 E(85289): 4.4e-33
Smith-Waterman score: 645; 46.3% identity (78.2% similar) in 216 aa overlap (21-231:12-222)
10 20 30 40 50
pF1KE5 MYRPRARAAPEGRVRGCAVPGTVL-LLLAYLAYLALGTGVFWTLEGRAAQDSSRSFQRDK
: :: :::::. :: ::. .: :: .: .: .:: .:
NP_001 MPSAGLCSCWGGRVLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEK
10 20 30 40 50
60 70 80 90 100 110
pF1KE5 WELLQNFTCLDRPALDSLIRDVVQAYKNGASLLSNTTSMGRWELVGSFFFSVSTITTIGY
..:.:.::::. :...... ...:. .:.. .:.:. . :.. .::::. ...:::::
NP_001 LRFLENYTCLDQWAMEQFVQVIMEAWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGY
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE5 GNLSPNTMAARLFCIFFALVGIPLNLVVLNRLGHLMQQGVNHWASRLGGTWQD-PDKARW
:::.:.: :...::.:.::.:::::.. ::.:: .. : :. :.: : ...
NP_001 GNLAPSTEAGQVFCVFYALLGIPLNVIFLNHLGTGLRA---HLAAI--ERWEDRPRRSQV
120 130 140 150 160
180 190 200 210 220 230
pF1KE5 LA--GSGALLS-GLLLFLLLPPLLFSHMEGWSYTEGFYFAFITLSTVGFGDYVIGMNPSQ
: : . .:. : :..:..::..:::.::::..::::::::::::.::::::.:.
NP_001 LQVLGLALFLTLGTLVILIFPPMVFSHVEGWSFSEGFYFAFITLSTIGFGDYVVGLRQGC
170 180 190 200 210 220
240 250 260 270 280 290
pF1KE5 RYPLWYKNMVSLWILFGMAWLALIIKLILSQLETPGRVCSCCHHSSKEDFKSQSWRQGPD
NP_001 GAKAAPGRRPRRGSTAARGVQVTPQDFPISKKGLGS
230 240 250 260
>>XP_016866835 (OMIM: 607369) PREDICTED: potassium chann (262 aa)
initn: 642 init1: 406 opt: 645 Z-score: 715.0 bits: 140.3 E(85289): 4.4e-33
Smith-Waterman score: 645; 46.3% identity (78.2% similar) in 216 aa overlap (21-231:12-222)
10 20 30 40 50
pF1KE5 MYRPRARAAPEGRVRGCAVPGTVL-LLLAYLAYLALGTGVFWTLEGRAAQDSSRSFQRDK
: :: :::::. :: ::. .: :: .: .: .:: .:
XP_016 MPSAGLCSCWGGRVLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEK
10 20 30 40 50
60 70 80 90 100 110
pF1KE5 WELLQNFTCLDRPALDSLIRDVVQAYKNGASLLSNTTSMGRWELVGSFFFSVSTITTIGY
..:.:.::::. :...... ...:. .:.. .:.:. . :.. .::::. ...:::::
XP_016 LRFLENYTCLDQWAMEQFVQVIMEAWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGY
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE5 GNLSPNTMAARLFCIFFALVGIPLNLVVLNRLGHLMQQGVNHWASRLGGTWQD-PDKARW
:::.:.: :...::.:.::.:::::.. ::.:: .. : :. :.: : ...
XP_016 GNLAPSTEAGQVFCVFYALLGIPLNVIFLNHLGTGLRA---HLAAI--ERWEDRPRRSQV
120 130 140 150 160
180 190 200 210 220 230
pF1KE5 LA--GSGALLS-GLLLFLLLPPLLFSHMEGWSYTEGFYFAFITLSTVGFGDYVIGMNPSQ
: : . .:. : :..:..::..:::.::::..::::::::::::.::::::.:.
XP_016 LQVLGLALFLTLGTLVILIFPPMVFSHVEGWSFSEGFYFAFITLSTIGFGDYVVGLRQGC
170 180 190 200 210 220
240 250 260 270 280 290
pF1KE5 RYPLWYKNMVSLWILFGMAWLALIIKLILSQLETPGRVCSCCHHSSKEDFKSQSWRQGPD
XP_016 GAKAAPGRRPRRGSTAARGVQVTPQDFPISKKGLGS
230 240 250 260
>>NP_001128577 (OMIM: 607369) potassium channel subfamil (322 aa)
initn: 663 init1: 406 opt: 643 Z-score: 711.6 bits: 139.9 E(85289): 6.8e-33
Smith-Waterman score: 647; 38.9% identity (68.3% similar) in 303 aa overlap (21-302:12-309)
10 20 30 40 50
pF1KE5 MYRPRARAAPEGRVRGCAVPGTVL-LLLAYLAYLALGTGVFWTLEGRAAQDSSRSFQRDK
: :: :::::. :: ::. .: :: .: .: .:: .:
NP_001 MPSAGLCSCWGGRVLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEK
10 20 30 40 50
60 70 80 90 100 110
pF1KE5 WELLQNFTCLDRPALDSLIRDVVQAYKNGASLLSNTTSMGRWELVGSFFFSVSTITTIGY
..:.:.::::. :...... ...:. .:.. .:.:. . :.. .::::. ...:::::
NP_001 LRFLENYTCLDQWAMEQFVQVIMEAWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGY
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE5 GNLSPNTMAARLFCIFFALVGIPLNLVVLNRLGHLMQQGVNHWASRLGGTWQD-PDKARW
:::.:.: :...::.:.::.:::::.. ::.:: .. : :. :.: : ...
NP_001 GNLAPSTEAGQVFCVFYALLGIPLNVIFLNHLGTGLRA---HLAAI--ERWEDRPRRSQV
120 130 140 150 160
180 190 200 210 220 230
pF1KE5 LA--GSGALLS-GLLLFLLLPPLLFSHMEGWSYTEGFYFAFITLSTVGFGDYVIG--MN-
: : . .:. : :..:..::..:::.::::..::::::::::::.::::::.: .:
NP_001 LQVLGLALFLTLGTLVILIFPPMVFSHVEGWSFSEGFYFAFITLSTIGFGDYVVGHPLNF
170 180 190 200 210 220
240 250 260 270 280
pF1KE5 -------PSQR-YPLWYKNMVSLWILFGMAWLALIIKLILSQLETPGRVCSC--CHHSSK
:::. . . . : : .. .. . :: ...:: . :. ..
NP_001 ITPSGLLPSQEPFQTPHGKPESQQIPGSFQKVSSMNVWPLSGMHSPGLAFPLPDCNIPDQ
230 240 250 260 270 280
290 300 310 320 330
pF1KE5 EDFKSQ---SWRQGPDREPESHSPQQGCYPEGPMGIIQHLEPSAHAAGCGKDS
: :. .:. : : :.:
NP_001 ERFRPLHPGAWKFWPLPLPSSNSKWAPMWLGSSAQV
290 300 310 320
>>XP_005249513 (OMIM: 603493) PREDICTED: potassium chann (496 aa)
initn: 630 init1: 301 opt: 594 Z-score: 655.4 bits: 130.2 E(85289): 9.2e-30
Smith-Waterman score: 594; 36.6% identity (71.3% similar) in 265 aa overlap (24-287:7-266)
10 20 30 40 50 60
pF1KE5 MYRPRARAAPEGRVRGCAVPGTVLLLLAYLAYLALGTGVFWTLEGRAAQDSSRSFQRDKW
:: : . :::.:...: .:: ....... .:
XP_005 MVDRGPLLTSAIIFYLAIGAAIFEVLEEPHWKEAKKNYYTQKL
10 20 30 40
70 80 90 100 110 120
pF1KE5 ELLQNFTCLDRPALDSLIRDVVQAYKNGASLLSNTTSMGRWELVGSFFFSVSTITTIGYG
.::..: :: . .::.... : .: .:... .: : .. :. ....:....:::::::
XP_005 HLLKEFPCLGQEGLDKILEVVSDAAGQGVAITGNQT-FNNWNWPNAMIFAATVITTIGYG
50 60 70 80 90 100
130 140 150 160 170
pF1KE5 NLSPNTMAARLFCIFFALVGIPLNLVVLNRLGHLMQQGVNHWASRLGGTW-QDPDKARWL
:..:.: :.::::.:..: :.:: :. .. ::... . :.::: . ::.
XP_005 NVAPKTPAGRLFCVFYGLFGVPLCLTWISALGKFF----GGRAKRLGQFLTKRGRKAQIT
110 120 130 140 150
180 190 200 210 220 230
pF1KE5 AGSGALLSGLLLFLLLPPLLFSHMEGWSYTEGFYFAFITLSTVGFGDYVIGMNPSQRYPL
.. :.:. :..::..: :::.: ::.:..:::.::.::::.: :.::: :
XP_005 CTVIFIVWGVLVHLVIPPFVFMVTEGWNYIEGLYYSFITISTIGFGDFVAGVNPSANYHA
160 170 180 190 200 210
240 250 260 270 280 290
pF1KE5 WYKNMVSLWILFGMAWLALIIKLILSQLETPGRVCSCCHHSSKEDFKSQSWRQGPDREPE
:. .: ::: .:.:::.:... .:.. .. . .. ::.:.:
XP_005 LYRYFVELWIYLGLAWLSLFVNWKVSMFVEVHKAIKKRRRRRKESFESSPHSRKALQVKG
220 230 240 250 260 270
300 310 320 330
pF1KE5 SHSPQQGCYPEGPMGIIQHLEPSAHAAGCGKDS
XP_005 STASKDVNIFSFLSKKEETYNDLIKQIGKKAMKTSGGGETGPGPGLGPQGGGLPALPPSL
280 290 300 310 320 330
>>NP_003731 (OMIM: 603493) potassium channel subfamily K (499 aa)
initn: 627 init1: 449 opt: 590 Z-score: 650.9 bits: 129.4 E(85289): 1.6e-29
Smith-Waterman score: 590; 35.6% identity (71.6% similar) in 264 aa overlap (24-287:7-269)
10 20 30 40 50 60
pF1KE5 MYRPRARAAPEGRVRGCAVPGTVLLLLAYLAYLALGTGVFWTLEGRAAQDSSRSFQRDKW
:: : . :::.:...: .:: ....... .:
NP_003 MVDRGPLLTSAIIFYLAIGAAIFEVLEEPHWKEAKKNYYTQKL
10 20 30 40
70 80 90 100 110 120
pF1KE5 ELLQNFTCLDRPALDSLIRDVVQAYKNGASLLSNTTSMGRWELVGSFFFSVSTITTIGYG
.::..: :: . .::.... : .: .:... .: : .. :. ....:....:::::::
NP_003 HLLKEFPCLGQEGLDKILEVVSDAAGQGVAITGNQT-FNNWNWPNAMIFAATVITTIGYG
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE5 NLSPNTMAARLFCIFFALVGIPLNLVVLNRLGHLMQQGVNHWASRLGGTWQDPDKARWLA
:..:.: :.::::.:..: :.:: :. .. ::... ... .. : . ::.
NP_003 NVAPKTPAGRLFCVFYGLFGVPLCLTWISALGKFFGGRAKRLGQFLTKRGVSLRKAQITC
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE5 GSGALLSGLLLFLLLPPLLFSHMEGWSYTEGFYFAFITLSTVGFGDYVIGMNPSQRYPLW
.. :.:. :..::..: :::.: ::.:..:::.::.::::.: :.::: :
NP_003 TVIFIVWGVLVHLVIPPFVFMVTEGWNYIEGLYYSFITISTIGFGDFVAGVNPSANYHAL
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE5 YKNMVSLWILFGMAWLALIIKLILSQLETPGRVCSCCHHSSKEDFKSQSWRQGPDREPES
:. .: ::: .:.:::.:... .:.. .. . .. ::.:.:
NP_003 YRYFVELWIYLGLAWLSLFVNWKVSMFVEVHKAIKKRRRRRKESFESSPHSRKALQVKGS
230 240 250 260 270 280
310 320 330
pF1KE5 HSPQQGCYPEGPMGIIQHLEPSAHAAGCGKDS
NP_003 TASKDVNIFSFLSKKEETYNDLIKQIGKKAMKTSGGGETGPGPGLGPQGGGLPALPPSLV
290 300 310 320 330 340
>>NP_201567 (OMIM: 605720) potassium channel subfamily K (393 aa)
initn: 464 init1: 239 opt: 576 Z-score: 637.0 bits: 126.4 E(85289): 9.7e-29
Smith-Waterman score: 582; 37.4% identity (60.5% similar) in 329 aa overlap (22-325:5-326)
10 20 30 40 50
pF1KE5 MYRPRARAAPEGRVRGCAVPGTVLLLLAY-LAYLALGTGVFWTLEGRAAQDSSRSFQRDK
:.: ::: : ::. :. :: .:: :...: . . .
NP_201 MRSTTLLALLALVLLYLVSGALVFRALEQPHEQQAQRELGEVR
10 20 30 40
60 70 80 90 100 110
pF1KE5 WELLQNFTCLDRPALDSLIRDVVQAYKNGASLLSNTTSMGR---WELVGSFFFSVSTITT
..:. :.. : ::..:..: .::. .:.:: . :.: ..:::: . :::
NP_201 EKFLRAHPCVSDQELGLLIKEVADALGGGADPETNSTSNSSHSAWDLGSAFFFSGTIITT
50 60 70 80 90 100
120 130 140 150 160 170
pF1KE5 IGYGNLSPNTMAARLFCIFFALVGIPLNLVVL----NRLGHLMQQGVNHWASRLGGTWQ-
:::::.. : :.::::::.::::::: ..: .::: ...:..: . . :.
NP_201 IGYGNVALRTDAGRLFCIFYALVGIPLFGILLAGVGDRLGSSLRHGIGHIEA-IFLKWHV
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE5 DPDKARWLAGSGALLSGLLLFLLLPPLLFSHMEGWSYTEGFYFAFITLSTVGFGDYVIGM
:. .: :.. :: : :::.: : ..: .:: :: :..::...::.:::::::: :
NP_201 PPELVRVLSAMLFLLIGCLLFVLTPTFVFCYMEDWSKLEAIYFVIVTLTTVGFGDYVAGA
170 180 190 200 210 220
240 250 260 270 280
pF1KE5 NPSQRYPLWYKNMVSLWILFGMAWLALIIKLILSQLETPGRVCSCCHHSSKEDFKSQ--S
.: : : :. .: .:::.:.:..: .. : . : :: : .. . .: :
NP_201 DPRQDSPA-YQPLVWFWILLGLAYFASVLTTIGNWL----RVVSRRTRAEMGGLTAQAAS
230 240 250 260 270
290 300 310 320 330
pF1KE5 W----------RQGPDREPESHS----PQQGCYPEGPMGIIQHLEPSAHAAGCGKDS
: : :: : . : : : :.: . : .:
NP_201 WTGTVTARVTQRAGPAAPPPEKEQPLLPPPPC-PAQPLGRPRSPSPPEKAQPPSPPTASA
280 290 300 310 320 330
NP_201 LDYPSENLAFIDESSDTQSERGCPLPRAPRGRRRPNPPRKPVRPRGPGRPRDKGVPV
340 350 360 370 380 390
332 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 00:25:08 2016 done: Tue Nov 8 00:25:09 2016
Total Scan time: 5.860 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]