Result of FASTA (ccds) for
pFN21AE5349
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5349, 297 aa
1>>>pF1KE5349 297 - 297 aa - 297 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.8286+/-0.000886; mu= 12.2846+/- 0.053
mean_var=62.3034+/-12.605, 0's: 0 Z-trim(104.8): 23 B-trim: 3 in 1/48
Lambda= 0.162487
statistics sampled from 8093 (8103) to 8093 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.628), E-opt: 0.2 (0.249), width: 16
Scan time: 2.050
The best scores are: opt bits E(32554)
CCDS55518.1 FMR1 gene_id:2332|Hs108|chrX ( 537) 1957 467.4 1e-131
CCDS76039.1 FMR1 gene_id:2332|Hs108|chrX ( 586) 1957 467.4 1.1e-131
CCDS55519.1 FMR1 gene_id:2332|Hs108|chrX ( 611) 1957 467.4 1.2e-131
CCDS14682.1 FMR1 gene_id:2332|Hs108|chrX ( 632) 1957 467.4 1.2e-131
CCDS46965.1 FXR1 gene_id:8087|Hs108|chr3 ( 539) 1478 355.1 6.5e-98
CCDS3238.1 FXR1 gene_id:8087|Hs108|chr3 ( 621) 1478 355.1 7.4e-98
CCDS45604.1 FXR2 gene_id:9513|Hs108|chr17 ( 673) 1411 339.4 4.3e-93
CCDS33894.1 FXR1 gene_id:8087|Hs108|chr3 ( 536) 1002 243.5 2.5e-64
>>CCDS55518.1 FMR1 gene_id:2332|Hs108|chrX (537 aa)
initn: 1957 init1: 1957 opt: 1957 Z-score: 2478.2 bits: 467.4 E(32554): 1e-131
Smith-Waterman score: 1957; 100.0% identity (100.0% similar) in 294 aa overlap (1-294:1-294)
10 20 30 40 50 60
pF1KE5 MEELVVEVRGSNGAFYKAFVKDVHEDSITVAFENNWQPDRQIPFHDVRFPPPVGYNKDIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 MEELVVEVRGSNGAFYKAFVKDVHEDSITVAFENNWQPDRQIPFHDVRFPPPVGYNKDIN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 ESDEVEVYSRANEKEPCCWWLAKVRMIKGEFYVIEYAACDATYNEIVTIERLRSVNPNKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 ESDEVEVYSRANEKEPCCWWLAKVRMIKGEFYVIEYAACDATYNEIVTIERLRSVNPNKP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 ATKDTFHKIKLDVPEDLRQMCAKEAAHKDFKKAVGAFSVTYDPENYQLVILSINEVTSKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 ATKDTFHKIKLDVPEDLRQMCAKEAAHKDFKKAVGAFSVTYDPENYQLVILSINEVTSKR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 AHMLIDMHFRSLRTKLSLIMRNEEASKQLESSRQLASRFHEQFIVREDLMGLAIGTHGAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 AHMLIDMHFRSLRTKLSLIMRNEEASKQLESSRQLASRFHEQFIVREDLMGLAIGTHGAN
190 200 210 220 230 240
250 260 270 280 290
pF1KE5 IQQARKVPGVTAIDLDEDTCTFHIYGEDQDAVKKARSFLEFAEDVIQVPRNLVGLKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 IQQARKVPGVTAIDLDEDTCTFHIYGEDQDAVKKARSFLEFAEDVIQVPRNLVGKVIGKN
250 260 270 280 290 300
CCDS55 GKLIQEIVDKSGVVRVRIEAENEKNVPQEEEIMPPNSLPSNNSRVGPNAPEEKKHLDIKE
310 320 330 340 350 360
>>CCDS76039.1 FMR1 gene_id:2332|Hs108|chrX (586 aa)
initn: 1957 init1: 1957 opt: 1957 Z-score: 2477.6 bits: 467.4 E(32554): 1.1e-131
Smith-Waterman score: 1957; 100.0% identity (100.0% similar) in 294 aa overlap (1-294:1-294)
10 20 30 40 50 60
pF1KE5 MEELVVEVRGSNGAFYKAFVKDVHEDSITVAFENNWQPDRQIPFHDVRFPPPVGYNKDIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS76 MEELVVEVRGSNGAFYKAFVKDVHEDSITVAFENNWQPDRQIPFHDVRFPPPVGYNKDIN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 ESDEVEVYSRANEKEPCCWWLAKVRMIKGEFYVIEYAACDATYNEIVTIERLRSVNPNKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS76 ESDEVEVYSRANEKEPCCWWLAKVRMIKGEFYVIEYAACDATYNEIVTIERLRSVNPNKP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 ATKDTFHKIKLDVPEDLRQMCAKEAAHKDFKKAVGAFSVTYDPENYQLVILSINEVTSKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS76 ATKDTFHKIKLDVPEDLRQMCAKEAAHKDFKKAVGAFSVTYDPENYQLVILSINEVTSKR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 AHMLIDMHFRSLRTKLSLIMRNEEASKQLESSRQLASRFHEQFIVREDLMGLAIGTHGAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS76 AHMLIDMHFRSLRTKLSLIMRNEEASKQLESSRQLASRFHEQFIVREDLMGLAIGTHGAN
190 200 210 220 230 240
250 260 270 280 290
pF1KE5 IQQARKVPGVTAIDLDEDTCTFHIYGEDQDAVKKARSFLEFAEDVIQVPRNLVGLKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS76 IQQARKVPGVTAIDLDEDTCTFHIYGEDQDAVKKARSFLEFAEDVIQVPRNLVGKVIGKN
250 260 270 280 290 300
CCDS76 GKLIQEIVDKSGVVRVRIEAENEKNVPQEEEIMPPNSLPSNNSRVGPNAPEEKKHLDIKE
310 320 330 340 350 360
>>CCDS55519.1 FMR1 gene_id:2332|Hs108|chrX (611 aa)
initn: 1957 init1: 1957 opt: 1957 Z-score: 2477.2 bits: 467.4 E(32554): 1.2e-131
Smith-Waterman score: 1957; 100.0% identity (100.0% similar) in 294 aa overlap (1-294:1-294)
10 20 30 40 50 60
pF1KE5 MEELVVEVRGSNGAFYKAFVKDVHEDSITVAFENNWQPDRQIPFHDVRFPPPVGYNKDIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 MEELVVEVRGSNGAFYKAFVKDVHEDSITVAFENNWQPDRQIPFHDVRFPPPVGYNKDIN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 ESDEVEVYSRANEKEPCCWWLAKVRMIKGEFYVIEYAACDATYNEIVTIERLRSVNPNKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 ESDEVEVYSRANEKEPCCWWLAKVRMIKGEFYVIEYAACDATYNEIVTIERLRSVNPNKP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 ATKDTFHKIKLDVPEDLRQMCAKEAAHKDFKKAVGAFSVTYDPENYQLVILSINEVTSKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 ATKDTFHKIKLDVPEDLRQMCAKEAAHKDFKKAVGAFSVTYDPENYQLVILSINEVTSKR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 AHMLIDMHFRSLRTKLSLIMRNEEASKQLESSRQLASRFHEQFIVREDLMGLAIGTHGAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 AHMLIDMHFRSLRTKLSLIMRNEEASKQLESSRQLASRFHEQFIVREDLMGLAIGTHGAN
190 200 210 220 230 240
250 260 270 280 290
pF1KE5 IQQARKVPGVTAIDLDEDTCTFHIYGEDQDAVKKARSFLEFAEDVIQVPRNLVGLKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 IQQARKVPGVTAIDLDEDTCTFHIYGEDQDAVKKARSFLEFAEDVIQVPRNLVGKVIGKN
250 260 270 280 290 300
CCDS55 GKLIQEIVDKSGVVRVRIEAENEKNVPQEEEIMPPNSLPSNNSRVGPNAPEEKKHLDIKE
310 320 330 340 350 360
>>CCDS14682.1 FMR1 gene_id:2332|Hs108|chrX (632 aa)
initn: 1957 init1: 1957 opt: 1957 Z-score: 2477.0 bits: 467.4 E(32554): 1.2e-131
Smith-Waterman score: 1957; 100.0% identity (100.0% similar) in 294 aa overlap (1-294:1-294)
10 20 30 40 50 60
pF1KE5 MEELVVEVRGSNGAFYKAFVKDVHEDSITVAFENNWQPDRQIPFHDVRFPPPVGYNKDIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 MEELVVEVRGSNGAFYKAFVKDVHEDSITVAFENNWQPDRQIPFHDVRFPPPVGYNKDIN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 ESDEVEVYSRANEKEPCCWWLAKVRMIKGEFYVIEYAACDATYNEIVTIERLRSVNPNKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 ESDEVEVYSRANEKEPCCWWLAKVRMIKGEFYVIEYAACDATYNEIVTIERLRSVNPNKP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 ATKDTFHKIKLDVPEDLRQMCAKEAAHKDFKKAVGAFSVTYDPENYQLVILSINEVTSKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 ATKDTFHKIKLDVPEDLRQMCAKEAAHKDFKKAVGAFSVTYDPENYQLVILSINEVTSKR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 AHMLIDMHFRSLRTKLSLIMRNEEASKQLESSRQLASRFHEQFIVREDLMGLAIGTHGAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 AHMLIDMHFRSLRTKLSLIMRNEEASKQLESSRQLASRFHEQFIVREDLMGLAIGTHGAN
190 200 210 220 230 240
250 260 270 280 290
pF1KE5 IQQARKVPGVTAIDLDEDTCTFHIYGEDQDAVKKARSFLEFAEDVIQVPRNLVGLKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 IQQARKVPGVTAIDLDEDTCTFHIYGEDQDAVKKARSFLEFAEDVIQVPRNLVGKVIGKN
250 260 270 280 290 300
CCDS14 GKLIQEIVDKSGVVRVRIEAENEKNVPQEEEIMPPNSLPSNNSRVGPNAPEEKKHLDIKE
310 320 330 340 350 360
>>CCDS46965.1 FXR1 gene_id:8087|Hs108|chr3 (539 aa)
initn: 1478 init1: 1478 opt: 1478 Z-score: 1871.3 bits: 355.1 E(32554): 6.5e-98
Smith-Waterman score: 1478; 74.1% identity (90.1% similar) in 294 aa overlap (1-294:1-294)
10 20 30 40 50 60
pF1KE5 MEELVVEVRGSNGAFYKAFVKDVHEDSITVAFENNWQPDRQIPFHDVRFPPPVGYNKDIN
: ::.::::::::::::.:.:::::::.::.:::::::.::.::..::.::: .:.:.
CCDS46 MAELTVEVRGSNGAFYKGFIKDVHEDSLTVVFENNWQPERQVPFNEVRLPPPPDIKKEIS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 ESDEVEVYSRANEKEPCCWWLAKVRMIKGEFYVIEYAACDATYNEIVTIERLRSVNPNKP
:.::::::::::..::: ::::::::.:::::::::::::::::::::.:::: :: ::
CCDS46 EGDEVEVYSRANDQEPCGWWLAKVRMMKGEFYVIEYAACDATYNEIVTFERLRPVNQNKT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 ATKDTFHKIKLDVPEDLRQMCAKEAAHKDFKKAVGAFSVTYDPENYQLVILSINEVTSKR
. :.:: : .:::::::. ::.: ::::::::::: . : ::. ::.::: .:.: ::
CCDS46 VKKNTFFKCTVDVPEDLREACANENAHKDFKKAVGACRIFYHPETTQLMILSASEATVKR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 AHMLIDMHFRSLRTKLSLIMRNEEASKQLESSRQLASRFHEQFIVREDLMGLAIGTHGAN
...: :::.::.:::: :. :::::.:.:: ..:::. :::.:.::::::::::::::.:
CCDS46 VNILSDMHLRSIRTKLMLMSRNEEATKHLECTKQLAAAFHEEFVVREDLMGLAIGTHGSN
190 200 210 220 230 240
250 260 270 280 290
pF1KE5 IQQARKVPGVTAIDLDEDTCTFHIYGEDQDAVKKARSFLEFAEDVIQVPRNLVGLKI
:::::::::::::.::::: ::.::::. :::::::.::::.:: :::::::::
CCDS46 IQQARKVPGVTAIELDEDTGTFRIYGESADAVKKARGFLEFVEDFIQVPRNLVGKVIGKN
250 260 270 280 290 300
CCDS46 GKVIQEIVDKSGVVRVRIEGDNENKLPREDGMVPFVFVGTKESIGNVQVLLEYHIAYLKE
310 320 330 340 350 360
>>CCDS3238.1 FXR1 gene_id:8087|Hs108|chr3 (621 aa)
initn: 1478 init1: 1478 opt: 1478 Z-score: 1870.3 bits: 355.1 E(32554): 7.4e-98
Smith-Waterman score: 1478; 74.1% identity (90.1% similar) in 294 aa overlap (1-294:1-294)
10 20 30 40 50 60
pF1KE5 MEELVVEVRGSNGAFYKAFVKDVHEDSITVAFENNWQPDRQIPFHDVRFPPPVGYNKDIN
: ::.::::::::::::.:.:::::::.::.:::::::.::.::..::.::: .:.:.
CCDS32 MAELTVEVRGSNGAFYKGFIKDVHEDSLTVVFENNWQPERQVPFNEVRLPPPPDIKKEIS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 ESDEVEVYSRANEKEPCCWWLAKVRMIKGEFYVIEYAACDATYNEIVTIERLRSVNPNKP
:.::::::::::..::: ::::::::.:::::::::::::::::::::.:::: :: ::
CCDS32 EGDEVEVYSRANDQEPCGWWLAKVRMMKGEFYVIEYAACDATYNEIVTFERLRPVNQNKT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 ATKDTFHKIKLDVPEDLRQMCAKEAAHKDFKKAVGAFSVTYDPENYQLVILSINEVTSKR
. :.:: : .:::::::. ::.: ::::::::::: . : ::. ::.::: .:.: ::
CCDS32 VKKNTFFKCTVDVPEDLREACANENAHKDFKKAVGACRIFYHPETTQLMILSASEATVKR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 AHMLIDMHFRSLRTKLSLIMRNEEASKQLESSRQLASRFHEQFIVREDLMGLAIGTHGAN
...: :::.::.:::: :. :::::.:.:: ..:::. :::.:.::::::::::::::.:
CCDS32 VNILSDMHLRSIRTKLMLMSRNEEATKHLECTKQLAAAFHEEFVVREDLMGLAIGTHGSN
190 200 210 220 230 240
250 260 270 280 290
pF1KE5 IQQARKVPGVTAIDLDEDTCTFHIYGEDQDAVKKARSFLEFAEDVIQVPRNLVGLKI
:::::::::::::.::::: ::.::::. :::::::.::::.:: :::::::::
CCDS32 IQQARKVPGVTAIELDEDTGTFRIYGESADAVKKARGFLEFVEDFIQVPRNLVGKVIGKN
250 260 270 280 290 300
CCDS32 GKVIQEIVDKSGVVRVRIEGDNENKLPREDGMVPFVFVGTKESIGNVQVLLEYHIAYLKE
310 320 330 340 350 360
>>CCDS45604.1 FXR2 gene_id:9513|Hs108|chr17 (673 aa)
initn: 1411 init1: 1411 opt: 1411 Z-score: 1784.8 bits: 339.4 E(32554): 4.3e-93
Smith-Waterman score: 1411; 71.5% identity (87.3% similar) in 291 aa overlap (4-294:14-304)
10 20 30 40 50
pF1KE5 MEELVVEVRGSNGAFYKAFVKDVHEDSITVAFENNWQPDRQIPFHDVRFP
: ::::::::::::.:::::::::.:. :::::: .::::: :::.:
CCDS45 MGGLASGGDVEPGLPVEVRGSNGAFYKGFVKDVHEDSVTIFFENNWQSERQIPFGDVRLP
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE5 PPVGYNKDINESDEVEVYSRANEKEPCCWWLAKVRMIKGEFYVIEYAACDATYNEIVTIE
::. :::.:.:.:::::::::::.::: ::::.:::.::.::::::::::::::::::.:
CCDS45 PPADYNKEITEGDEVEVYSRANEQEPCGWWLARVRMMKGDFYVIEYAACDATYNEIVTLE
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE5 RLRSVNPNKPATKDTFHKIKLDVPEDLRQMCAKEAAHKDFKKAVGAFSVTYDPENYQLVI
::: :::: ::: .: :. . ::::::. :..: .::.::::.:: . . : .: :
CCDS45 RLRPVNPNPLATKGSFFKVTMAVPEDLREACSNENVHKEFKKALGANCIFLNITNSELFI
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE5 LSINEVTSKRAHMLIDMHFRSLRTKLSLIMRNEEASKQLESSRQLASRFHEQFIVREDLM
:: .:. ::: .: ::::::::::: :. :::::.:.::.:.:::. :.:.: ::::::
CCDS45 LSTTEAPVKRASLLGDMHFRSLRTKLLLMSRNEEATKHLETSKQLAAAFQEEFTVREDLM
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE5 GLAIGTHGANIQQARKVPGVTAIDLDEDTCTFHIYGEDQDAVKKARSFLEFAEDVIQVPR
:::::::::::::::::::::::.: :.::::.:::: .: ..:::.:::.:: .::::
CCDS45 GLAIGTHGANIQQARKVPGVTAIELGEETCTFRIYGETPEACRQARSYLEFSEDSVQVPR
250 260 270 280 290 300
pF1KE5 NLVGLKI
::::
CCDS45 NLVGKVIGKNGKVIQEIVDKSGVVRVRVEGDNDKKNPREEGMVPFIFVGTRENISNAQAL
310 320 330 340 350 360
>>CCDS33894.1 FXR1 gene_id:8087|Hs108|chr3 (536 aa)
initn: 1002 init1: 1002 opt: 1002 Z-score: 1268.3 bits: 243.5 E(32554): 2.5e-64
Smith-Waterman score: 1002; 73.7% identity (88.5% similar) in 209 aa overlap (86-294:1-209)
60 70 80 90 100 110
pF1KE5 NKDINESDEVEVYSRANEKEPCCWWLAKVRMIKGEFYVIEYAACDATYNEIVTIERLRSV
:.:::::::::::::::::::::.:::: :
CCDS33 MMKGEFYVIEYAACDATYNEIVTFERLRPV
10 20 30
120 130 140 150 160 170
pF1KE5 NPNKPATKDTFHKIKLDVPEDLRQMCAKEAAHKDFKKAVGAFSVTYDPENYQLVILSINE
: :: . :.:: : .:::::::. ::.: ::::::::::: . : ::. ::.::: .:
CCDS33 NQNKTVKKNTFFKCTVDVPEDLREACANENAHKDFKKAVGACRIFYHPETTQLMILSASE
40 50 60 70 80 90
180 190 200 210 220 230
pF1KE5 VTSKRAHMLIDMHFRSLRTKLSLIMRNEEASKQLESSRQLASRFHEQFIVREDLMGLAIG
.: ::...: :::.::.:::: :. :::::.:.:: ..:::. :::.:.:::::::::::
CCDS33 ATVKRVNILSDMHLRSIRTKLMLMSRNEEATKHLECTKQLAAAFHEEFVVREDLMGLAIG
100 110 120 130 140 150
240 250 260 270 280 290
pF1KE5 THGANIQQARKVPGVTAIDLDEDTCTFHIYGEDQDAVKKARSFLEFAEDVIQVPRNLVGL
:::.::::::::::::::.::::: ::.::::. :::::::.::::.:: :::::::::
CCDS33 THGSNIQQARKVPGVTAIELDEDTGTFRIYGESADAVKKARGFLEFVEDFIQVPRNLVGK
160 170 180 190 200 210
pF1KE5 KI
CCDS33 VIGKNGKVIQEIVDKSGVVRVRIEGDNENKLPREDGMVPFVFVGTKESIGNVQVLLEYHI
220 230 240 250 260 270
297 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 00:00:54 2016 done: Tue Nov 8 00:00:54 2016
Total Scan time: 2.050 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]