Result of FASTA (omim) for
pFN21AE5336
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5336, 268 aa
1>>>pF1KE5336 268 - 268 aa - 268 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.0493+/-0.000336; mu= 15.8087+/- 0.021
mean_var=59.3189+/-11.755, 0's: 0 Z-trim(115.3): 313 B-trim: 0 in 0/53
Lambda= 0.166524
statistics sampled from 25401 (25720) to 25401 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.684), E-opt: 0.2 (0.302), width: 16
Scan time: 6.640
The best scores are: opt bits E(85289)
NP_009203 (OMIM: 167800,601405) chymotrypsin-C pre ( 268) 1874 458.3 6.5e-129
NP_254275 (OMIM: 609443) chymotrypsin-like elastas ( 269) 1174 290.2 2.8e-78
XP_011538852 (OMIM: 167800,601405) PREDICTED: chym ( 280) 1134 280.6 2.2e-75
NP_056933 (OMIM: 609444) chymotrypsin-like elastas ( 269) 1087 269.3 5.4e-72
NP_001962 (OMIM: 130120) chymotrypsin-like elastas ( 258) 852 212.8 5.2e-55
NP_001897 (OMIM: 118890) chymotrypsinogen B isofor ( 263) 681 171.7 1.2e-42
NP_001898 (OMIM: 118888) chymotrypsin-like proteas ( 264) 649 164.0 2.5e-40
NP_001305325 (OMIM: 229000,612423) plasma kallikre ( 436) 578 147.1 5.3e-35
XP_016863673 (OMIM: 229000,612423) PREDICTED: plas ( 436) 578 147.1 5.3e-35
NP_000883 (OMIM: 229000,612423) plasma kallikrein ( 638) 578 147.2 7.2e-35
XP_016863670 (OMIM: 229000,612423) PREDICTED: plas ( 649) 578 147.2 7.3e-35
XP_011530232 (OMIM: 229000,612423) PREDICTED: plas ( 649) 578 147.2 7.3e-35
XP_005262880 (OMIM: 264900,612416) PREDICTED: coag ( 536) 574 146.2 1.2e-34
XP_006714200 (OMIM: 264900,612416) PREDICTED: coag ( 610) 574 146.2 1.4e-34
NP_000119 (OMIM: 264900,612416) coagulation factor ( 625) 574 146.2 1.4e-34
XP_005262878 (OMIM: 264900,612416) PREDICTED: coag ( 626) 574 146.2 1.4e-34
NP_001243246 (OMIM: 605511) transmembrane protease ( 453) 566 144.2 4e-34
NP_001275679 (OMIM: 606751) transmembrane protease ( 413) 560 142.7 1e-33
NP_001275680 (OMIM: 606751) transmembrane protease ( 448) 560 142.8 1.1e-33
NP_110397 (OMIM: 606751) transmembrane protease se ( 457) 560 142.8 1.1e-33
NP_115780 (OMIM: 605511) transmembrane protease se ( 327) 554 141.3 2.2e-33
NP_076927 (OMIM: 605511) transmembrane protease se ( 454) 554 141.3 3e-33
NP_000292 (OMIM: 173350,217090) plasminogen isofor ( 810) 556 141.9 3.5e-33
NP_001265514 (OMIM: 605236,614595) atrial natriure ( 938) 553 141.3 6.4e-33
NP_006578 (OMIM: 605236,614595) atrial natriuretic (1042) 553 141.3 7e-33
XP_016882221 (OMIM: 142440) PREDICTED: serine prot ( 393) 547 139.6 8.4e-33
XP_005255530 (OMIM: 609343) PREDICTED: brain-speci ( 317) 545 139.1 9.8e-33
NP_071402 (OMIM: 609343) brain-specific serine pro ( 317) 545 139.1 9.8e-33
NP_002142 (OMIM: 142440) serine protease hepsin pr ( 417) 546 139.4 1e-32
NP_892028 (OMIM: 142440) serine protease hepsin pr ( 417) 546 139.4 1e-32
XP_005258895 (OMIM: 142440) PREDICTED: serine prot ( 417) 546 139.4 1e-32
XP_006723244 (OMIM: 142440) PREDICTED: serine prot ( 417) 546 139.4 1e-32
XP_016882220 (OMIM: 142440) PREDICTED: serine prot ( 417) 546 139.4 1e-32
XP_005265767 (OMIM: 605369) PREDICTED: transmembra ( 301) 532 136.0 8.2e-32
NP_004253 (OMIM: 605369) transmembrane protease se ( 418) 532 136.0 1.1e-31
NP_001277025 (OMIM: 606565) transmembrane protease ( 290) 528 135.0 1.5e-31
NP_002763 (OMIM: 226200,606635) enteropeptidase pr (1019) 534 136.7 1.6e-31
XP_011527961 (OMIM: 226200,606635) PREDICTED: ente (1034) 534 136.7 1.7e-31
XP_011527960 (OMIM: 226200,606635) PREDICTED: ente (1037) 534 136.7 1.7e-31
XP_011527959 (OMIM: 226200,606635) PREDICTED: ente (1049) 534 136.7 1.7e-31
XP_011527956 (OMIM: 226200,606635) PREDICTED: ente (1064) 534 136.7 1.7e-31
XP_011527958 (OMIM: 226200,606635) PREDICTED: ente (1064) 534 136.7 1.7e-31
XP_011527957 (OMIM: 226200,606635) PREDICTED: ente (1064) 534 136.7 1.7e-31
NP_001167023 (OMIM: 606565) transmembrane protease ( 397) 528 135.1 2e-31
NP_001277023 (OMIM: 606565) transmembrane protease ( 412) 528 135.1 2.1e-31
XP_016864340 (OMIM: 605369) PREDICTED: transmembra ( 234) 525 134.2 2.1e-31
NP_001077416 (OMIM: 606565) transmembrane protease ( 432) 528 135.1 2.2e-31
NP_001167022 (OMIM: 606565) transmembrane protease ( 435) 528 135.1 2.2e-31
NP_063947 (OMIM: 606565) transmembrane protease se ( 437) 528 135.1 2.2e-31
NP_077078 (OMIM: 191081) tryptase beta-2 prepropro ( 275) 521 133.3 4.7e-31
>>NP_009203 (OMIM: 167800,601405) chymotrypsin-C preprop (268 aa)
initn: 1874 init1: 1874 opt: 1874 Z-score: 2435.3 bits: 458.3 E(85289): 6.5e-129
Smith-Waterman score: 1874; 100.0% identity (100.0% similar) in 268 aa overlap (1-268:1-268)
10 20 30 40 50 60
pF1KE5 MLGITVLAALLACASSCGVPSFPPNLSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 MLGITVLAALLACASSCGVPSFPPNLSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 GTLIASNFVLTAAHCISNTRTYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 GTLIASNFVLTAAHCISNTRTYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 DIALIKLAEHVELSDTIQVACLPEKDSLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 DIALIKLAEHVELSDTIQVACLPEKDSLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 VDHATCSRIDWWGFRVKKTMVCAGGDGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 VDHATCSRIDWWGFRVKKTMVCAGGDGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSR
190 200 210 220 230 240
250 260
pF1KE5 RGCNTRKKPVVYTRVSAYIDWINEKMQL
::::::::::::::::::::::::::::
NP_009 RGCNTRKKPVVYTRVSAYIDWINEKMQL
250 260
>>NP_254275 (OMIM: 609443) chymotrypsin-like elastase fa (269 aa)
initn: 1151 init1: 720 opt: 1174 Z-score: 1526.4 bits: 290.2 E(85289): 2.8e-78
Smith-Waterman score: 1174; 63.4% identity (80.0% similar) in 265 aa overlap (1-263:1-263)
10 20 30 40 50 60
pF1KE5 MLGITVLAALLACASSCGVPSFPPNLSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCG
:. .:..:.: : ::: :..:: .. ::::::.:::.:::::.:::: .: : ::::
NP_254 MIRTLLLSTLVAGALSCGDPTYPPYVT-RVVGGEEARPNSWPWQVSLQYSSNGKWYHTCG
10 20 30 40 50
70 80 90 100 110
pF1KE5 GTLIASNFVLTAAHCISNTRTYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLR-
:.:::...:::::::::..:::::..:..:: : : ::: :.:. : ::: ::. .
NP_254 GSLIANSWVLTAAHCISSSRTYRVGLGRHNLYVA-ESGSLAVSVSKIVVHKDWNSNQISK
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE5 -NDIALIKLAEHVELSDTIQVACLPEKDSLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQ
:::::.:::. : :.: ::.:::: ..::..::::::::::: ::: . : ::::
NP_254 GNDIALLKLANPVSLTDKIQLACLPPAGTILPNNYPCYVTGWGRLQTNGAVPDVLQQGRL
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE5 PVVDHATCSRIDWWGFRVKKTMVCAGGDGVISACNGDSGGPLNCQLENGSWEVFGIVSFG
:::.:::: ::: :: .:.:::::::::.:::::::::::: .: :.: ::::::
NP_254 LVVDYATCSSSAWWGSSVKTSMICAGGDGVISSCNGDSGGPLNCQASDGRWQVHGIVSFG
180 190 200 210 220 230
240 250 260
pF1KE5 SRRGCNTRKKPVVYTRVSAYIDWINEKMQL
:: ::: .:: :.:::: ::::::
NP_254 SRLGCNYYHKPSVFTRVSNYIDWINSVIANN
240 250 260
>>XP_011538852 (OMIM: 167800,601405) PREDICTED: chymotry (280 aa)
initn: 1130 init1: 1130 opt: 1134 Z-score: 1474.2 bits: 280.6 E(85289): 2.2e-75
Smith-Waterman score: 1134; 91.3% identity (95.1% similar) in 183 aa overlap (1-177:1-183)
10 20 30 40 50 60
pF1KE5 MLGITVLAALLACASSCGVPSFPPNLSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MLGITVLAALLACASSCGVPSFPPNLSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 GTLIASNFVLTAAHCISNTRTYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GTLIASNFVLTAAHCISNTRTYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRN
70 80 90 100 110 120
130 140 150 160 170
pF1KE5 DIALIKLAEHVELSDTIQVACLPEKDSLLPKDYPCYVTGWGRLW------TNGPIADKLQ
:::::::::::::::::::::::::::::::::::::::::::: :. :.....
XP_011 DIALIKLAEHVELSDTIQVACLPEKDSLLPKDYPCYVTGWGRLWRGLRWPTELPVGERFL
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE5 QGLQPVVDHATCSRIDWWGFRVKKTMVCAGGDGVISACNGDSGGPLNCQLENGSWEVFGI
:.
XP_011 GGVWHRQLWLPAGLQHPQEAGSLHPGVRLHRLDQRENAAVICCWERRQRVPATAINFLLL
190 200 210 220 230 240
>>NP_056933 (OMIM: 609444) chymotrypsin-like elastase fa (269 aa)
initn: 1066 init1: 664 opt: 1087 Z-score: 1413.5 bits: 269.3 E(85289): 5.4e-72
Smith-Waterman score: 1087; 59.2% identity (76.6% similar) in 265 aa overlap (1-263:1-263)
10 20 30 40 50 60
pF1KE5 MLGITVLAALLACASSCGVPSFPPNLSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCG
:. .:..:.: : :::: .. :..: :..:::.:::.:::::.:::: .: : ::::
NP_056 MIRTLLLSTLVAGALSCGVSTYAPDMS-RMLGGEEARPNSWPWQVSLQYSSNGQWYHTCG
10 20 30 40 50
70 80 90 100 110
pF1KE5 GTLIASNFVLTAAHCISNTRTYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLR-
:.:::...:::::::::.. ::: .:..:: : : ::: :.:. : ::: ::. .
NP_056 GSLIANSWVLTAAHCISSSGIYRVMLGQHNLYVA-ESGSLAVSVSKIVVHKDWNSDQVSK
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE5 -NDIALIKLAEHVELSDTIQVACLPEKDSLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQ
:::::.:::. : :.: ::.:::: ..::..::::::::::: ::: . : :.::
NP_056 GNDIALLKLANPVSLTDKIQLACLPPAGTILPNNYPCYVTGWGRLQTNGALPDDLKQGRL
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE5 PVVDHATCSRIDWWGFRVKKTMVCAGGDGVISACNGDSGGPLNCQLENGSWEVFGIVSFG
:::.:::: ::: :: .:.:::::::: .:::::::::::: .: ::: :: :.
NP_056 LVVDYATCSSSGWWGSTVKTNMICAGGDGVICTCNGDSGGPLNCQASDGRWEVHGIGSLT
180 190 200 210 220 230
240 250 260
pF1KE5 SRRGCNTRKKPVVYTRVSAYIDWINEKMQL
: ::: :: ..:::: : ::::
NP_056 SVLGCNYYYKPSIFTRVSNYNDWINSVIANN
240 250 260
>>NP_001962 (OMIM: 130120) chymotrypsin-like elastase fa (258 aa)
initn: 418 init1: 418 opt: 852 Z-score: 1108.6 bits: 212.8 E(85289): 5.2e-55
Smith-Waterman score: 852; 52.3% identity (77.0% similar) in 243 aa overlap (24-263:13-252)
10 20 30 40 50 60
pF1KE5 MLGITVLAALLACASSCGVPSFPPNLSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCG
:. .:::::: .: .::: :::::: .. . ::::
NP_001 MLVLYGHSTQDLPETNARVVGGTEAGRNSWPSQISLQYRSGGSRYHTCG
10 20 30 40
70 80 90 100 110
pF1KE5 GTLIASNFVLTAAHCISNTRTYRVAVGKNNLEVEDEEGS-LFVGVDTIHVHKRWNA--LL
:::: .:.:.:::::.. .:.::..: .:: .: :. .:.:. : :: ::. .
NP_001 GTLIRQNWVMTAAHCVDYQKTFRVVAGDHNLSQND--GTEQYVSVQKIVVHPYWNSDNVA
50 60 70 80 90 100
120 130 140 150 160 170
pF1KE5 LRNDIALIKLAEHVELSDTIQVACLPEKDSLLPKDYPCYVTGWGRLWTNGPIADKLQQGL
::::..::. : :.. .:.. ::.. ..: .. :::.::::. ::: .:. :::.
NP_001 AGYDIALLRLAQSVTLNSYVQLGVLPQEGAILANNSPCYITGWGKTKTNGQLAQTLQQAY
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE5 QPVVDHATCSRIDWWGFRVKKTMVCAGGDGVISACNGDSGGPLNCQLENGSWEVFGIVSF
: ::.: :: ..:: ::.:::::::::: :.:.:::::::.: : ::.. : :..::
NP_001 LPSVDYAICSSSSYWGSTVKNTMVCAGGDGVRSGCQGDSGGPLHC-LVNGKYSVHGVTSF
170 180 190 200 210 220
240 250 260
pF1KE5 GSRRGCNTRKKPVVYTRVSAYIDWINEKMQL
: ::::. .::.:.:.:::::.:::
NP_001 VSSRGCNVSRKPTVFTQVSAYISWINNVIASN
230 240 250
>>NP_001897 (OMIM: 118890) chymotrypsinogen B isoform 1 (263 aa)
initn: 576 init1: 165 opt: 681 Z-score: 886.5 bits: 171.7 E(85289): 1.2e-42
Smith-Waterman score: 681; 42.5% identity (70.3% similar) in 259 aa overlap (9-264:11-258)
10 20 30 40 50
pF1KE5 MLGITVLAALLACASSCGVPSFPPNLS--ARVVGGEDARPHSWPWQISLQYLKNDTWR
.:.. : .::::.. : :: .:.:.:::: : :::::.::: . :
NP_001 MASLWLLSCFSLVGAAFGCGVPAIHPVLSGLSRIVNGEDAVPGSWPWQVSLQ---DKTGF
10 20 30 40 50
60 70 80 90 100 110
pF1KE5 HTCGGTLIASNFVLTAAHCISNTRTYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNAL
: :::.::. ..:.::::: ..:: :.:. . . :::. . . . . ... :
NP_001 HFCGGSLISEDWVVTAAHC--GVRTSDVVVAGEFDQGSDEENIQVLKIAKVFKNPKFSIL
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE5 LLRNDIALIKLAEHVELSDTIQVACLPEKDSLLPKDYPCYVTGWGRLWTNG-PIADKLQQ
. :::.:.::: ...:.:....::: :. .: : .::::. :. :::::
NP_001 TVNNDITLLKLATPARFSQTVSAVCLPSADDDFPAGTLCATTGWGKTKYNANKTPDKLQQ
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE5 GLQPVVDHATCSRIDWWGFRVKKTMVCAGGDGVISACNGDSGGPLNCQLENGSWEVFGIV
. :....: :.. :: :. .:.:::..:: :.: ::::::: :: ..:.: . :::
NP_001 AALPLLSNAECKKS--WGRRITDVMICAGASGV-SSCMGDSGGPLVCQ-KDGAWTLVGIV
180 190 200 210 220 230
240 250 260
pF1KE5 SFGSRRGCNTRKKPVVYTRVSAYIDWINEKMQL
:.:: :.: ..: ::.::. : :...
NP_001 SWGSDT-CST-SSPGVYARVTKLIPWVQKILAAN
240 250 260
>>NP_001898 (OMIM: 118888) chymotrypsin-like protease CT (264 aa)
initn: 453 init1: 150 opt: 649 Z-score: 844.9 bits: 164.0 E(85289): 2.5e-40
Smith-Waterman score: 649; 39.9% identity (67.2% similar) in 268 aa overlap (1-264:3-259)
10 20 30 40 50
pF1KE5 MLGITVLAALLACASSCGVPSFPPNLS--ARVVGGEDARPHSWPWQISLQYLKNDTWR
.:..:. .::. . .::.:.. : :: :.:.::.: :::::.::: ...
NP_001 MLLLSLTLSLVLLGSSWGCGIPAIKPALSFSQRIVNGENAVLGSWPWQVSLQ---DSSGF
10 20 30 40 50
60 70 80 90 100 110
pF1KE5 HTCGGTLIASNFVLTAAHC-ISNTRTYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNA
: :::.::....:.::::: .: : . :..:. . . . : ..:. .: ::.
NP_001 HFCGGSLISQSWVVTAAHCNVSPGRHF-VVLGEYD-RSSNAEPLQVLSVSRAITHPSWNS
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE5 LLLRNDIALIKLAEHVELSDTIQVACLPEKDSLLPKDYPCYVTGWGRLWTNGPIAD-KLQ
. ::..:.::: .. . :. .:: .. : . : .:::::: : .. .::
NP_001 TTMNNDVTLLKLASPAQYTTRISPVCLASSNEALTEGLTCVTTGWGRLSGVGNVTPAHLQ
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE5 QGLQPVVDHATCSRIDWWGFRVKKTMVCAGGDGVISACNGDSGGPLNCQLENGSWEVFGI
: :.: : . .:: . .:.:::: :. :.:.::::::: :: : .: ..::
NP_001 QVALPLVTVNQCRQ--YWGSSITDSMICAGGAGA-SSCQGDSGGPLVCQKGN-TWVLIGI
180 190 200 210 220 230
240 250 260
pF1KE5 VSFGSRRGCNTRKKPVVYTRVSAYIDWINEKMQL
::.:.. .::.: :.:::::: . :::.
NP_001 VSWGTK-NCNVRA-PAVYTRVSKFSTWINQVIAYN
240 250 260
>>NP_001305325 (OMIM: 229000,612423) plasma kallikrein i (436 aa)
initn: 492 init1: 197 opt: 578 Z-score: 749.4 bits: 147.1 E(85289): 5.3e-35
Smith-Waterman score: 578; 39.2% identity (64.1% similar) in 245 aa overlap (27-267:186-424)
10 20 30 40 50
pF1KE5 MLGITVLAALLACASSCGVPSFPPNLSARVVGGEDARPHSWPWQISLQYLKNDTWR
:.:.::: .. ::::.::: .: . :
NP_001 TRIAYGTQGSSGYSLRLCNTGDNSVCTTKTSTRIVGGTNSSWGEWPWQVSLQ-VKLTAQR
160 170 180 190 200 210
60 70 80 90 100 110
pF1KE5 HTCGGTLIASNFVLTAAHCISNT---RTYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRW
: :::.::. ..:::::::... ..:. : :: . . . : . : .:. .
NP_001 HLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSGILNLS-DITKDTPFSQIKEIIIHQNY
220 230 240 250 260 270
120 130 140 150 160 170
pF1KE5 NALLLRNDIALIKLAEHVELSDTIQVACLPEKDSLLPKDYPCYVTGWGRLWTNGPIADKL
.. .::::::: .. .. . ::: : . :.::::: .: : . :
NP_001 KVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGDTSTIYTNCWVTGWGFSKEKGEIQNIL
280 290 300 310 320 330
180 190 200 210 220 230
pF1KE5 QQGLQPVVDHATCSRIDWWGFRVKKTMVCAG-GDGVISACNGDSGGPLNCQLENGSWEVF
:. :.: . :.. . ... . ::::: .: .::.::::::: :. .:: :..
NP_001 QKVNIPLVTNEECQK-RYQDYKITQRMVCAGYKEGGKDACKGDSGGPLVCK-HNGMWRLV
340 350 360 370 380 390
240 250 260
pF1KE5 GIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKMQL
::.:.: .:: :..: :::.:. :.::: :: :
NP_001 GITSWG--EGCARREQPGVYTKVAEYMDWILEKTQSSDGKAQMQSPA
400 410 420 430
>>XP_016863673 (OMIM: 229000,612423) PREDICTED: plasma k (436 aa)
initn: 492 init1: 197 opt: 578 Z-score: 749.4 bits: 147.1 E(85289): 5.3e-35
Smith-Waterman score: 578; 39.2% identity (64.1% similar) in 245 aa overlap (27-267:186-424)
10 20 30 40 50
pF1KE5 MLGITVLAALLACASSCGVPSFPPNLSARVVGGEDARPHSWPWQISLQYLKNDTWR
:.:.::: .. ::::.::: .: . :
XP_016 TRIAYGTQGSSGYSLRLCNTGDNSVCTTKTSTRIVGGTNSSWGEWPWQVSLQ-VKLTAQR
160 170 180 190 200 210
60 70 80 90 100 110
pF1KE5 HTCGGTLIASNFVLTAAHCISNT---RTYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRW
: :::.::. ..:::::::... ..:. : :: . . . : . : .:. .
XP_016 HLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSGILNLS-DITKDTPFSQIKEIIIHQNY
220 230 240 250 260 270
120 130 140 150 160 170
pF1KE5 NALLLRNDIALIKLAEHVELSDTIQVACLPEKDSLLPKDYPCYVTGWGRLWTNGPIADKL
.. .::::::: .. .. . ::: : . :.::::: .: : . :
XP_016 KVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGDTSTIYTNCWVTGWGFSKEKGEIQNIL
280 290 300 310 320 330
180 190 200 210 220 230
pF1KE5 QQGLQPVVDHATCSRIDWWGFRVKKTMVCAG-GDGVISACNGDSGGPLNCQLENGSWEVF
:. :.: . :.. . ... . ::::: .: .::.::::::: :. .:: :..
XP_016 QKVNIPLVTNEECQK-RYQDYKITQRMVCAGYKEGGKDACKGDSGGPLVCK-HNGMWRLV
340 350 360 370 380 390
240 250 260
pF1KE5 GIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKMQL
::.:.: .:: :..: :::.:. :.::: :: :
XP_016 GITSWG--EGCARREQPGVYTKVAEYMDWILEKTQSSDGKAQMQSPA
400 410 420 430
>>NP_000883 (OMIM: 229000,612423) plasma kallikrein isof (638 aa)
initn: 472 init1: 197 opt: 578 Z-score: 746.9 bits: 147.2 E(85289): 7.2e-35
Smith-Waterman score: 578; 39.2% identity (64.1% similar) in 245 aa overlap (27-267:388-626)
10 20 30 40 50
pF1KE5 MLGITVLAALLACASSCGVPSFPPNLSARVVGGEDARPHSWPWQISLQYLKNDTWR
:.:.::: .. ::::.::: .: . :
NP_000 TRIAYGTQGSSGYSLRLCNTGDNSVCTTKTSTRIVGGTNSSWGEWPWQVSLQ-VKLTAQR
360 370 380 390 400 410
60 70 80 90 100 110
pF1KE5 HTCGGTLIASNFVLTAAHCISNT---RTYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRW
: :::.::. ..:::::::... ..:. : :: . . . : . : .:. .
NP_000 HLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSGILNLS-DITKDTPFSQIKEIIIHQNY
420 430 440 450 460 470
120 130 140 150 160 170
pF1KE5 NALLLRNDIALIKLAEHVELSDTIQVACLPEKDSLLPKDYPCYVTGWGRLWTNGPIADKL
.. .::::::: .. .. . ::: : . :.::::: .: : . :
NP_000 KVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGDTSTIYTNCWVTGWGFSKEKGEIQNIL
480 490 500 510 520 530
180 190 200 210 220 230
pF1KE5 QQGLQPVVDHATCSRIDWWGFRVKKTMVCAG-GDGVISACNGDSGGPLNCQLENGSWEVF
:. :.: . :.. . ... . ::::: .: .::.::::::: :. .:: :..
NP_000 QKVNIPLVTNEECQK-RYQDYKITQRMVCAGYKEGGKDACKGDSGGPLVCK-HNGMWRLV
540 550 560 570 580 590
240 250 260
pF1KE5 GIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKMQL
::.:.: .:: :..: :::.:. :.::: :: :
NP_000 GITSWG--EGCARREQPGVYTKVAEYMDWILEKTQSSDGKAQMQSPA
600 610 620 630
268 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 23:53:42 2016 done: Mon Nov 7 23:53:43 2016
Total Scan time: 6.640 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]