FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE5334, 261 aa
  1>>>pF1KE5334 261 - 261 aa - 261 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.0436+/-0.000393; mu= 16.2221+/- 0.024
 mean_var=63.6557+/-12.839, 0's: 0 Z-trim(112.0): 6  B-trim: 27 in 2/53
 Lambda= 0.160752
 statistics sampled from 20816 (20820) to 20816 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.62), E-opt: 0.2 (0.244), width:  16
 Scan time:  5.740

The best scores are:                                      opt bits E(85289)
NP_037479 (OMIM: 300767) replication protein A 30  ( 261) 1717 406.9 1.9e-113
NP_002937 (OMIM: 179836) replication protein A 32  ( 270)  708 172.9 5.5e-43
NP_001284487 (OMIM: 179836) replication protein A  ( 278)  701 171.2 1.7e-42
NP_001273005 (OMIM: 179836) replication protein A  ( 174)  441 110.8 1.7e-24


>>NP_037479 (OMIM: 300767) replication protein A 30 kDa   (261 aa)
 initn: 1717 init1: 1717 opt: 1717  Z-score: 2157.5  bits: 406.9 E(85289): 1.9e-113
Smith-Waterman score: 1717; 100.0% identity (100.0% similar) in 261 aa overlap (1-261:1-261)

               10        20        30        40        50        60
pF1KE5 MSKSGFGSYGSISAADGASGGSDQLCERDATPAIKTQRPKVRIQDVVPCNVNQLLSSTVF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 MSKSGFGSYGSISAADGASGGSDQLCERDATPAIKTQRPKVRIQDVVPCNVNQLLSSTVF
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE5 DPVFKVRGIIVSQVSIVGVIRGAEKASNHICYKIDDMTAKPIEARQWFGREKVKQVTPLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 DPVFKVRGIIVSQVSIVGVIRGAEKASNHICYKIDDMTAKPIEARQWFGREKVKQVTPLS
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE5 VGVYVKVFGILKCPTGTKSLEVLKIHVLEDMNEFTVHILETVNAHMMLDKARRDTTVESV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 VGVYVKVFGILKCPTGTKSLEVLKIHVLEDMNEFTVHILETVNAHMMLDKARRDTTVESV
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE5 PVSPSEVNDAGDNDESHRNFIQDEVLRLIHECPHQEGKSIHELRAQLCDLSVKAIKEAID
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 PVSPSEVNDAGDNDESHRNFIQDEVLRLIHECPHQEGKSIHELRAQLCDLSVKAIKEAID
              190       200       210       220       230       240

              250       260 
pF1KE5 YLTVEGHIYPTVDREHFKSAD
       :::::::::::::::::::::
NP_037 YLTVEGHIYPTVDREHFKSAD
              250       260 

>>NP_002937 (OMIM: 179836) replication protein A 32 kDa   (270 aa)
 initn: 702 init1: 315 opt: 708  Z-score: 892.7  bits: 172.9 E(85289): 5.5e-43
Smith-Waterman score: 708; 45.9% identity (72.2% similar) in 270 aa overlap (1-261:1-268)

               10        20        30          40        50        
pF1KE5 MSKSGFGSYGSISAADGASGGSDQLCERDATPAIKT--QRPKVRIQDVVPCNVNQLLSST
       : .::: :::: :   :..::  :     ..:: .   .. ..: : .:::...::::.:
NP_002 MWNSGFESYGSSSY--GGAGGYTQSPGGFGSPAPSQAEKKSRARAQHIVPCTISQLLSAT
               10          20        30        40        50        

       60        70        80        90       100       110        
pF1KE5 VFDPVFKVRGIIVSQVSIVGVIRGAEKASNHICYKIDDMTAKPIEARQWFGREKVK-QVT
       . : ::.. .. .:::.:::.:: :::: ..: :::::::: :...:::   . .. . :
NP_002 LVDEVFRIGNVEISQVTIVGIIRHAEKAPTNIVYKIDDMTAAPMDVRQWVDTDDTSSENT
       60        70        80        90       100       110        

       120       130       140       150       160       170       
pF1KE5 PLSVGVYVKVFGILKCPTGTKSLEVLKIHVLEDMNEFTVHILETVNAHMMLDKARRDTTV
        .   .:::: : :.   . ::: ..::  ::::::::.::::..::::.:.::  . ..
NP_002 VVPPETYVKVAGHLRSFQNKKSLVAFKIMPLEDMNEFTTHILEVINAHMVLSKANSQPSA
      120       130       140       150       160       170        

       180          190       200          210       220       230 
pF1KE5 ESVPVS-P--SEVNDAGDNDESHRNFI---QDEVLRLIHECPHQEGKSIHELRAQLCDLS
         .:.: :  ::... : :.    : .   :..:: ::. ::. :: ....:. ::  .:
NP_002 GRAPISNPGMSEAGNFGGNSFMPANGLTVAQNQVLNLIKACPRPEGLNFQDLKNQLKHMS
      180       190       200       210       220       230        

             240       250       260   
pF1KE5 VKAIKEAIDYLTVEGHIYPTVDREHFKSAD  
       :..::.:.:.:. ::::: ::: .::::.:  
NP_002 VSSIKQAVDFLSNEGHIYSTVDDDHFKSTDAE
      240       250       260       270

>>NP_001284487 (OMIM: 179836) replication protein A 32 k  (278 aa)
 initn: 695 init1: 308 opt: 701  Z-score: 883.7  bits: 171.2 E(85289): 1.7e-42
Smith-Waterman score: 701; 45.7% identity (71.7% similar) in 269 aa overlap (2-261:10-276)

                       10        20        30          40        50
pF1KE5         MSKSGFGSYGSISAADGASGGSDQLCERDATPAIKT--QRPKVRIQDVVPCN
                :  :: :::: :   :..::  :     ..:: .   .. ..: : .:::.
NP_001 MGRGDRNKRSIRGFESYGSSSY--GGAGGYTQSPGGFGSPAPSQAEKKSRARAQHIVPCT
               10        20          30        40        50        

               60        70        80        90       100       110
pF1KE5 VNQLLSSTVFDPVFKVRGIIVSQVSIVGVIRGAEKASNHICYKIDDMTAKPIEARQWFGR
       ..::::.:. : ::.. .. .:::.:::.:: :::: ..: :::::::: :...:::   
NP_001 ISQLLSATLVDEVFRIGNVEISQVTIVGIIRHAEKAPTNIVYKIDDMTAAPMDVRQWVDT
       60        70        80        90       100       110        

               120       130       140       150       160         
pF1KE5 EKVK-QVTPLSVGVYVKVFGILKCPTGTKSLEVLKIHVLEDMNEFTVHILETVNAHMMLD
       . .. . : .   .:::: : :.   . ::: ..::  ::::::::.::::..::::.:.
NP_001 DDTSSENTVVPPETYVKVAGHLRSFQNKKSLVAFKIMPLEDMNEFTTHILEVINAHMVLS
      120       130       140       150       160       170        

     170       180          190       200          210       220   
pF1KE5 KARRDTTVESVPVS-P--SEVNDAGDNDESHRNFI---QDEVLRLIHECPHQEGKSIHEL
       ::  . ..  .:.: :  ::... : :.    : .   :..:: ::. ::. :: ....:
NP_001 KANSQPSAGRAPISNPGMSEAGNFGGNSFMPANGLTVAQNQVLNLIKACPRPEGLNFQDL
      180       190       200       210       220       230        

           230       240       250       260   
pF1KE5 RAQLCDLSVKAIKEAIDYLTVEGHIYPTVDREHFKSAD  
       . ::  .::..::.:.:.:. ::::: ::: .::::.:  
NP_001 KNQLKHMSVSSIKQAVDFLSNEGHIYSTVDDDHFKSTDAE
      240       250       260       270        

>>NP_001273005 (OMIM: 179836) replication protein A 32 k  (174 aa)
 initn: 446 init1: 213 opt: 441  Z-score: 560.8  bits: 110.8 E(85289): 1.7e-24
Smith-Waterman score: 441; 45.3% identity (72.1% similar) in 172 aa overlap (97-261:1-172)

         70        80        90       100       110        120     
pF1KE5 RGIIVSQVSIVGVIRGAEKASNHICYKIDDMTAKPIEARQWFGREKVK-QVTPLSVGVYV
                                     ::: :...:::   . .. . : .   .::
NP_001                               MTAAPMDVRQWVDTDDTSSENTVVPPETYV
                                             10        20        30

         130       140       150       160       170       180     
pF1KE5 KVFGILKCPTGTKSLEVLKIHVLEDMNEFTVHILETVNAHMMLDKARRDTTVESVPVS-P
       :: : :.   . ::: ..::  ::::::::.::::..::::.:.::  . ..  .:.: :
NP_001 KVAGHLRSFQNKKSLVAFKIMPLEDMNEFTTHILEVINAHMVLSKANSQPSAGRAPISNP
               40        50        60        70        80        90

            190       200          210       220       230         
pF1KE5 --SEVNDAGDNDESHRNFI---QDEVLRLIHECPHQEGKSIHELRAQLCDLSVKAIKEAI
         ::... : :.    : .   :..:: ::. ::. :: ....:. ::  .::..::.:.
NP_001 GMSEAGNFGGNSFMPANGLTVAQNQVLNLIKACPRPEGLNFQDLKNQLKHMSVSSIKQAV
              100       110       120       130       140       150

     240       250       260   
pF1KE5 DYLTVEGHIYPTVDREHFKSAD  
       :.:. ::::: ::: .::::.:  
NP_001 DFLSNEGHIYSTVDDDHFKSTDAE
              160       170    




261 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Mon Nov  7 23:52:38 2016 done: Mon Nov  7 23:52:39 2016
 Total Scan time:  5.740 Total Display time: -0.010

Function used was FASTA [36.3.4 Apr, 2011]