FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE5318, 286 aa
  1>>>pF1KE5318 286 - 286 aa - 286 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 7.5919+/-0.000689; mu= 6.9492+/- 0.042
 mean_var=155.8566+/-31.043, 0's: 0 Z-trim(116.0): 5  B-trim: 16 in 1/52
 Lambda= 0.102733
 statistics sampled from 16538 (16540) to 16538 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.817), E-opt: 0.2 (0.508), width:  16
 Scan time:  2.720

The best scores are:                                      opt bits E(32554)
CCDS11496.1 HEXIM2 gene_id:124790|Hs108|chr17      ( 286) 1969 302.6 2.2e-82
CCDS11495.1 HEXIM1 gene_id:10614|Hs108|chr17       ( 359)  454 78.1   1e-14


>>CCDS11496.1 HEXIM2 gene_id:124790|Hs108|chr17           (286 aa)
 initn: 1969 init1: 1969 opt: 1969  Z-score: 1592.5  bits: 302.6 E(32554): 2.2e-82
Smith-Waterman score: 1969; 100.0% identity (100.0% similar) in 286 aa overlap (1-286:1-286)

               10        20        30        40        50        60
pF1KE5 MMATPNQTACNAESPVALEEAKTSGAPGSPQTPPERHDSGGSLPLTPRMESHSEDEDLAG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 MMATPNQTACNAESPVALEEAKTSGAPGSPQTPPERHDSGGSLPLTPRMESHSEDEDLAG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE5 AVGGLGWNSRSPRTQSPGGCSAEAVLARKKHRRRPSKRKRHWRPYLELSWAEKQQRDERQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 AVGGLGWNSRSPRTQSPGGCSAEAVLARKKHRRRPSKRKRHWRPYLELSWAEKQQRDERQ
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE5 SQRASRVREEMFAKGQPVAPYNTTQFLMNDRDPEEPNLDVPHGISHPGSSGESEAGDSDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 SQRASRVREEMFAKGQPVAPYNTTQFLMNDRDPEEPNLDVPHGISHPGSSGESEAGDSDG
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE5 RGRAHGEFQRKDFSETYERFHTESLQGRSKQELVRDYLELEKRLSQAEEETRRLQQLQAC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 RGRAHGEFQRKDFSETYERFHTESLQGRSKQELVRDYLELEKRLSQAEEETRRLQQLQAC
              190       200       210       220       230       240

              250       260       270       280      
pF1KE5 TGQQSCRQVEELAAEVQRLRTENQRLRQENQMWNREGCRCDEEPGT
       ::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 TGQQSCRQVEELAAEVQRLRTENQRLRQENQMWNREGCRCDEEPGT
              250       260       270       280      

>>CCDS11495.1 HEXIM1 gene_id:10614|Hs108|chr17            (359 aa)
 initn: 775 init1: 396 opt: 454  Z-score: 377.6  bits: 78.1 E(32554): 1e-14
Smith-Waterman score: 683; 45.8% identity (64.3% similar) in 286 aa overlap (5-272:73-345)

                                         10        20        30    
pF1KE5                           MMATPNQTACNAESPVALEEAKTSGAPGSPQTPP
                                     : ::    ::    :  :  :  :. ..  
CCDS11 EDSRWQSRAFPQLGGRPGPEGEGSLESQPPPLQTQACPESSCLREGEK--GQNGDDSS--
             50        60        70        80        90            

           40        50        60        70          80            
pF1KE5 ERHDSGGSLPLTPRMESHSEDEDLAGAVGGLGWNSRSPRTQSP--GGC----SAEAVLAR
           .::..:   ..:   : : ::        .:.. .  .:  ::     . .  :..
CCDS11 ----AGGDFPPPAEVEPTPEAELLAQPCH----DSEASKLGAPAAGGEEEWGQQQRQLGK
          100       110       120           130       140       150

       90       100       110       120       130       140        
pF1KE5 KKHRRRPSKRKRHWRPYLELSWAEKQQRDERQSQRASRVREEMFAKGQPVAPYNTTQFLM
       :::::::::.::::.:: .:.: ::.. ::.:: ::::.: :::::::::::::::::::
CCDS11 KKHRRRPSKKKRHWKPYYKLTWEEKKKFDEKQSLRASRIRAEMFAKGQPVAPYNTTQFLM
              160       170       180       190       200       210

      150       160             170             180       190      
pF1KE5 NDRDPEEPNLDV------PHGISHPGSS------GESEAGDSDGRGRAHGEFQRKDFSET
       .:.: :::.: .        . :   :.      :  : : ::: :   .:: ..:::::
CCDS11 DDHDQEEPDLKTGLYSKRAAAKSDDTSDDDFMEEGGEEDGGSDGMGGDGSEFLQRDFSET
              220       230       240       250       260       270

        200       210       220       230       240       250      
pF1KE5 YERFHTESLQGRSKQELVRDYLELEKRLSQAEEETRRLQQLQACTGQQSCRQVEELAAEV
       :::.::::::. :::::...:::::: ::. :.:. ::.  .   : .. : :.::  :.
CCDS11 YERYHTESLQNMSKQELIKEYLELEKCLSRMEDENNRLRLESKRLGGDDAR-VRELELEL
              280       290       300       310       320          

        260       270       280      
pF1KE5 QRLRTENQRLRQENQMWNREGCRCDEEPGT
       .:::.:: .:  ::..              
CCDS11 DRLRAENLQLLTENELHRQQERAPLSKFGD
     330       340       350         




286 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Tue Nov  8 07:31:17 2016 done: Tue Nov  8 07:31:18 2016
 Total Scan time:  2.720 Total Display time: -0.010

Function used was FASTA [36.3.4 Apr, 2011]