Result of FASTA (omim) for
pFN21AE5293
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5293, 178 aa
1>>>pF1KE5293 178 - 178 aa - 178 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.8858+/-0.000252; mu= 7.5513+/- 0.016
mean_var=115.1435+/-23.245, 0's: 0 Z-trim(124.7): 199 B-trim: 1979 in 1/51
Lambda= 0.119524
statistics sampled from 46689 (46891) to 46689 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.843), E-opt: 0.2 (0.55), width: 16
Scan time: 5.570
The best scores are: opt bits E(85289)
XP_016881664 (OMIM: 605467) PREDICTED: neurotrophi ( 296) 434 84.2 2.1e-16
XP_016881663 (OMIM: 605467) PREDICTED: neurotrophi ( 548) 419 81.7 2.1e-15
NP_057408 (OMIM: 605467) neurotrophin receptor-int ( 548) 419 81.7 2.1e-15
XP_011524629 (OMIM: 605467) PREDICTED: neurotrophi ( 548) 419 81.7 2.1e-15
NP_001265663 (OMIM: 605467) neurotrophin receptor- ( 611) 419 81.8 2.3e-15
NP_057409 (OMIM: 605467) neurotrophin receptor-int ( 621) 419 81.8 2.3e-15
NP_598009 (OMIM: 605467) neurotrophin receptor-int ( 653) 419 81.8 2.4e-15
NP_001253962 (OMIM: 194550) myeloid zinc finger 1 ( 290) 409 79.8 4.1e-15
NP_932172 (OMIM: 194550) myeloid zinc finger 1 iso ( 734) 409 80.1 8.7e-15
NP_003413 (OMIM: 194550) myeloid zinc finger 1 iso ( 734) 409 80.1 8.7e-15
XP_011525566 (OMIM: 194550) PREDICTED: myeloid zin ( 764) 409 80.1 9e-15
XP_005259261 (OMIM: 194550) PREDICTED: myeloid zin ( 775) 409 80.1 9.1e-15
NP_862829 (OMIM: 165260) zinc finger and SCAN doma ( 491) 396 77.7 3e-14
XP_011525219 (OMIM: 165260) PREDICTED: zinc finger ( 491) 396 77.7 3e-14
NP_001308045 (OMIM: 165260) zinc finger and SCAN d ( 491) 396 77.7 3e-14
XP_006723255 (OMIM: 165260) PREDICTED: zinc finger ( 491) 396 77.7 3e-14
XP_016882235 (OMIM: 165260) PREDICTED: zinc finger ( 333) 393 77.1 3.1e-14
NP_001308046 (OMIM: 165260) zinc finger and SCAN d ( 333) 393 77.1 3.1e-14
XP_006718374 (OMIM: 605016) PREDICTED: zinc finger ( 517) 372 73.6 5.4e-13
NP_037382 (OMIM: 605016) zinc finger protein 215 [ ( 517) 372 73.6 5.4e-13
XP_011520954 (OMIM: 608387) PREDICTED: zinc finger ( 285) 359 71.2 1.6e-12
XP_006710939 (OMIM: 611315) PREDICTED: zinc finger ( 989) 366 72.7 1.9e-12
XP_016857727 (OMIM: 611315) PREDICTED: zinc finger (1042) 366 72.8 2e-12
XP_005271228 (OMIM: 611315) PREDICTED: zinc finger (1042) 366 72.8 2e-12
XP_016857726 (OMIM: 611315) PREDICTED: zinc finger (1043) 366 72.8 2e-12
XP_006710937 (OMIM: 611315) PREDICTED: zinc finger (1043) 366 72.8 2e-12
NP_660281 (OMIM: 611315) zinc finger and SCAN doma (1043) 366 72.8 2e-12
NP_001128127 (OMIM: 608387) zinc finger protein 21 ( 459) 359 71.3 2.3e-12
NP_004211 (OMIM: 608387) zinc finger protein 213 [ ( 459) 359 71.3 2.3e-12
XP_006720895 (OMIM: 604191) PREDICTED: zinc finger ( 644) 361 71.8 2.4e-12
XP_006720894 (OMIM: 604191) PREDICTED: zinc finger ( 670) 361 71.8 2.5e-12
NP_005732 (OMIM: 604191) zinc finger protein 263 [ ( 683) 361 71.8 2.5e-12
XP_011520646 (OMIM: 604191) PREDICTED: zinc finger ( 683) 361 71.8 2.5e-12
XP_016868074 (OMIM: 601261) PREDICTED: zinc finger ( 450) 358 71.2 2.6e-12
XP_006716176 (OMIM: 601261) PREDICTED: zinc finger ( 473) 358 71.2 2.7e-12
NP_666019 (OMIM: 601261) zinc finger and SCAN doma ( 473) 358 71.2 2.7e-12
XP_005250625 (OMIM: 601261) PREDICTED: zinc finger ( 473) 358 71.2 2.7e-12
XP_016868073 (OMIM: 601261) PREDICTED: zinc finger ( 473) 358 71.2 2.7e-12
XP_011529614 (OMIM: 300627) PREDICTED: zinc finger ( 518) 354 70.5 4.7e-12
NP_689908 (OMIM: 300627) zinc finger protein 449 [ ( 518) 354 70.5 4.7e-12
XP_006711901 (OMIM: 613911) PREDICTED: zinc finger ( 381) 344 68.7 1.2e-11
NP_001316662 (OMIM: 613911) zinc finger protein 49 ( 386) 344 68.7 1.2e-11
XP_016858082 (OMIM: 613911) PREDICTED: zinc finger ( 405) 344 68.7 1.3e-11
XP_011542618 (OMIM: 613911) PREDICTED: zinc finger ( 412) 344 68.7 1.3e-11
XP_011542617 (OMIM: 613911) PREDICTED: zinc finger ( 427) 344 68.7 1.3e-11
XP_011542616 (OMIM: 613911) PREDICTED: zinc finger ( 427) 344 68.7 1.3e-11
XP_016858081 (OMIM: 613911) PREDICTED: zinc finger ( 443) 344 68.7 1.4e-11
NP_116141 (OMIM: 613911) zinc finger protein 496 i ( 587) 344 68.8 1.7e-11
XP_011542614 (OMIM: 613911) PREDICTED: zinc finger ( 618) 344 68.8 1.8e-11
XP_016858079 (OMIM: 613911) PREDICTED: zinc finger ( 618) 344 68.8 1.8e-11
>>XP_016881664 (OMIM: 605467) PREDICTED: neurotrophin re (296 aa)
initn: 411 init1: 411 opt: 434 Z-score: 415.6 bits: 84.2 E(85289): 2.1e-16
Smith-Waterman score: 434; 55.6% identity (72.2% similar) in 133 aa overlap (19-144:143-273)
10 20 30 40
pF1KE5 MLPRPKAPASPRRPQTPTPSEQDADPGPASPRDTEAQRLRFRQFQYHV
:::: . : : : :: : :::::.:.
XP_016 VLTLNQEVAGPRNAQIQALYAEDGSLSADAPSEQVQQQGK-HPGDPEAARQRFRQFRYKD
120 130 140 150 160 170
50 60 70 80 90 100
pF1KE5 ASGPHLALGQLWTLCRQWLRPEARSKEQMLELLVLEQFLGALPSKMRTWVQSQGPRSCRE
.::. :: :: ::.:::.:.::::::.:::::::::::::: :.::::.:: :..:.:
XP_016 MTGPREALDQLRELCHQWLQPKARSKEQILELLVLEQFLGALPVKLRTWVESQHPENCQE
180 190 200 210 220 230
110 120 130 140 150 160
pF1KE5 AASLVEDLTQMCQQEGERRR------LRAPGR-ARGPDVSEDRTALLPAHIAPTPARPLP
...::: .: : ..:: :. : : ::: .:::
XP_016 VVALVEGVTWMSEEEGASDLPGCGCGLQPGGVGAAGPD-TEDRVPRCDAGDLWAPGLCGV
240 250 260 270 280 290
170
pF1KE5 TSKPLLPRGCVFNYFYI
XP_016 GDYTGK
>>XP_016881663 (OMIM: 605467) PREDICTED: neurotrophin re (548 aa)
initn: 411 init1: 389 opt: 419 Z-score: 397.6 bits: 81.7 E(85289): 2.1e-15
Smith-Waterman score: 419; 61.0% identity (80.0% similar) in 105 aa overlap (19-123:38-141)
10 20 30 40
pF1KE5 MLPRPKAPASPRRPQTPTPSEQDADPGPASPRDTEAQRLRFRQFQYHV
:::: . : : : :: : :::::.:.
XP_016 VLTLNQEVAGPRNAQIQALYAEDGSLSADAPSEQVQQQGK-HPGDPEAARQRFRQFRYKD
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE5 ASGPHLALGQLWTLCRQWLRPEARSKEQMLELLVLEQFLGALPSKMRTWVQSQGPRSCRE
.::. :: :: ::.:::.:.::::::.:::::::::::::: :.::::.:: :..:.:
XP_016 MTGPREALDQLRELCHQWLQPKARSKEQILELLVLEQFLGALPVKLRTWVESQHPENCQE
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE5 AASLVEDLTQMCQQEGERRRLRAPGRARGPDVSEDRTALLPAHIAPTPARPLPTSKPLLP
...::: .: : ..:
XP_016 VVALVEGVTWMSEEEVLPAGQPAEGTTCCLEVTAQQEEKQEDAAICPVTVLPEEPVTFQD
130 140 150 160 170 180
>>NP_057408 (OMIM: 605467) neurotrophin receptor-interac (548 aa)
initn: 411 init1: 389 opt: 419 Z-score: 397.6 bits: 81.7 E(85289): 2.1e-15
Smith-Waterman score: 419; 61.0% identity (80.0% similar) in 105 aa overlap (19-123:38-141)
10 20 30 40
pF1KE5 MLPRPKAPASPRRPQTPTPSEQDADPGPASPRDTEAQRLRFRQFQYHV
:::: . : : : :: : :::::.:.
NP_057 VLTLNQEVAGPRNAQIQALYAEDGSLSADAPSEQVQQQGK-HPGDPEAARQRFRQFRYKD
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE5 ASGPHLALGQLWTLCRQWLRPEARSKEQMLELLVLEQFLGALPSKMRTWVQSQGPRSCRE
.::. :: :: ::.:::.:.::::::.:::::::::::::: :.::::.:: :..:.:
NP_057 MTGPREALDQLRELCHQWLQPKARSKEQILELLVLEQFLGALPVKLRTWVESQHPENCQE
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE5 AASLVEDLTQMCQQEGERRRLRAPGRARGPDVSEDRTALLPAHIAPTPARPLPTSKPLLP
...::: .: : ..:
NP_057 VVALVEGVTWMSEEEVLPAGQPAEGTTCCLEVTAQQEEKQEDAAICPVTVLPEEPVTFQD
130 140 150 160 170 180
>>XP_011524629 (OMIM: 605467) PREDICTED: neurotrophin re (548 aa)
initn: 411 init1: 389 opt: 419 Z-score: 397.6 bits: 81.7 E(85289): 2.1e-15
Smith-Waterman score: 419; 61.0% identity (80.0% similar) in 105 aa overlap (19-123:38-141)
10 20 30 40
pF1KE5 MLPRPKAPASPRRPQTPTPSEQDADPGPASPRDTEAQRLRFRQFQYHV
:::: . : : : :: : :::::.:.
XP_011 VLTLNQEVAGPRNAQIQALYAEDGSLSADAPSEQVQQQGK-HPGDPEAARQRFRQFRYKD
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE5 ASGPHLALGQLWTLCRQWLRPEARSKEQMLELLVLEQFLGALPSKMRTWVQSQGPRSCRE
.::. :: :: ::.:::.:.::::::.:::::::::::::: :.::::.:: :..:.:
XP_011 MTGPREALDQLRELCHQWLQPKARSKEQILELLVLEQFLGALPVKLRTWVESQHPENCQE
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE5 AASLVEDLTQMCQQEGERRRLRAPGRARGPDVSEDRTALLPAHIAPTPARPLPTSKPLLP
...::: .: : ..:
XP_011 VVALVEGVTWMSEEEVLPAGQPAEGTTCCLEVTAQQEEKQEDAAICPVTVLPEEPVTFQD
130 140 150 160 170 180
>>NP_001265663 (OMIM: 605467) neurotrophin receptor-inte (611 aa)
initn: 389 init1: 389 opt: 419 Z-score: 396.9 bits: 81.8 E(85289): 2.3e-15
Smith-Waterman score: 419; 61.0% identity (80.0% similar) in 105 aa overlap (19-123:101-204)
10 20 30 40
pF1KE5 MLPRPKAPASPRRPQTPTPSEQDADPGPASPRDTEAQRLRFRQFQYHV
:::: . : : : :: : :::::.:.
NP_001 VLTLNQEVAGPRNAQIQALYAEDGSLSADAPSEQVQQQGK-HPGDPEAARQRFRQFRYKD
80 90 100 110 120
50 60 70 80 90 100
pF1KE5 ASGPHLALGQLWTLCRQWLRPEARSKEQMLELLVLEQFLGALPSKMRTWVQSQGPRSCRE
.::. :: :: ::.:::.:.::::::.:::::::::::::: :.::::.:: :..:.:
NP_001 MTGPREALDQLRELCHQWLQPKARSKEQILELLVLEQFLGALPVKLRTWVESQHPENCQE
130 140 150 160 170 180
110 120 130 140 150 160
pF1KE5 AASLVEDLTQMCQQEGERRRLRAPGRARGPDVSEDRTALLPAHIAPTPARPLPTSKPLLP
...::: .: : ..:
NP_001 VVALVEGVTWMSEEEVLPAGQPAEGTTCCLEVTAQQEEKQEDAAICPVTVLPEEPVTFQD
190 200 210 220 230 240
>>NP_057409 (OMIM: 605467) neurotrophin receptor-interac (621 aa)
initn: 389 init1: 389 opt: 419 Z-score: 396.8 bits: 81.8 E(85289): 2.3e-15
Smith-Waterman score: 419; 61.0% identity (80.0% similar) in 105 aa overlap (19-123:111-214)
10 20 30 40
pF1KE5 MLPRPKAPASPRRPQTPTPSEQDADPGPASPRDTEAQRLRFRQFQYHV
:::: . : : : :: : :::::.:.
NP_057 VLTLNQEVAGPRNAQIQALYAEDGSLSADAPSEQVQQQGK-HPGDPEAARQRFRQFRYKD
90 100 110 120 130
50 60 70 80 90 100
pF1KE5 ASGPHLALGQLWTLCRQWLRPEARSKEQMLELLVLEQFLGALPSKMRTWVQSQGPRSCRE
.::. :: :: ::.:::.:.::::::.:::::::::::::: :.::::.:: :..:.:
NP_057 MTGPREALDQLRELCHQWLQPKARSKEQILELLVLEQFLGALPVKLRTWVESQHPENCQE
140 150 160 170 180 190
110 120 130 140 150 160
pF1KE5 AASLVEDLTQMCQQEGERRRLRAPGRARGPDVSEDRTALLPAHIAPTPARPLPTSKPLLP
...::: .: : ..:
NP_057 VVALVEGVTWMSEEEVLPAGQPAEGTTCCLEVTAQQEEKQEDAAICPVTVLPEEPVTFQD
200 210 220 230 240 250
>>NP_598009 (OMIM: 605467) neurotrophin receptor-interac (653 aa)
initn: 389 init1: 389 opt: 419 Z-score: 396.5 bits: 81.8 E(85289): 2.4e-15
Smith-Waterman score: 419; 61.0% identity (80.0% similar) in 105 aa overlap (19-123:143-246)
10 20 30 40
pF1KE5 MLPRPKAPASPRRPQTPTPSEQDADPGPASPRDTEAQRLRFRQFQYHV
:::: . : : : :: : :::::.:.
NP_598 VLTLNQEVAGPRNAQIQALYAEDGSLSADAPSEQVQQQGK-HPGDPEAARQRFRQFRYKD
120 130 140 150 160 170
50 60 70 80 90 100
pF1KE5 ASGPHLALGQLWTLCRQWLRPEARSKEQMLELLVLEQFLGALPSKMRTWVQSQGPRSCRE
.::. :: :: ::.:::.:.::::::.:::::::::::::: :.::::.:: :..:.:
NP_598 MTGPREALDQLRELCHQWLQPKARSKEQILELLVLEQFLGALPVKLRTWVESQHPENCQE
180 190 200 210 220 230
110 120 130 140 150 160
pF1KE5 AASLVEDLTQMCQQEGERRRLRAPGRARGPDVSEDRTALLPAHIAPTPARPLPTSKPLLP
...::: .: : ..:
NP_598 VVALVEGVTWMSEEEVLPAGQPAEGTTCCLEVTAQQEEKQEDAAICPVTVLPEEPVTFQD
240 250 260 270 280 290
>>NP_001253962 (OMIM: 194550) myeloid zinc finger 1 isof (290 aa)
initn: 415 init1: 351 opt: 409 Z-score: 392.4 bits: 79.8 E(85289): 4.1e-15
Smith-Waterman score: 409; 45.9% identity (66.5% similar) in 170 aa overlap (4-165:2-165)
10 20 30 40 50
pF1KE5 MLPRPKAPASPRR--PQTPTPS----EQDADPGPASPRDT--EAQRLRFRQFQYHVASGP
:: . .:: : :. : :.. . : :. : :: ::::: :.:. :.::
NP_001 MRPAVLGSPDRAPPEDEGPVMVKLEDSEEEGEAALWDPGPEAARLRFRCFRYEEATGP
10 20 30 40 50
60 70 80 90 100 110
pF1KE5 HLALGQLWTLCRQWLRPEARSKEQMLELLVLEQFLGALPSKMRTWVQSQGPRSCREAASL
. ::.:: :::::::::.:::::::::::::::::::: .... ::.: : : .:::.:
NP_001 QEALAQLRELCRQWLRPEVRSKEQMLELLVLEQFLGALPPEIQARVQGQRPGSPEEAAAL
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE5 VEDLTQMCQQEGERRRLRAPGRARGPDVSEDRTALLPAHIAPTPARPLPTSKPLLPRGCV
:. : . . : :: . . ...: .: .. . :. . : : :: .:
NP_001 VDGLRR--EPGGPRRWVTV--QVQGQEVLSEK--MEPSSFQPLPETEPPTPEPGPKTPPR
120 130 140 150 160 170
pF1KE5 FNYFYI
NP_001 TMQESPLGLQVKEESEVTEDSDFLESGPLAATQESVPTLLPEEAQRCGTVLDQIFPHSKT
180 190 200 210 220 230
>>NP_932172 (OMIM: 194550) myeloid zinc finger 1 isoform (734 aa)
initn: 379 init1: 351 opt: 409 Z-score: 386.4 bits: 80.1 E(85289): 8.7e-15
Smith-Waterman score: 409; 45.9% identity (66.5% similar) in 170 aa overlap (4-165:2-165)
10 20 30 40 50
pF1KE5 MLPRPKAPASPRR--PQTPTPS----EQDADPGPASPRDT--EAQRLRFRQFQYHVASGP
:: . .:: : :. : :.. . : :. : :: ::::: :.:. :.::
NP_932 MRPAVLGSPDRAPPEDEGPVMVKLEDSEEEGEAALWDPGPEAARLRFRCFRYEEATGP
10 20 30 40 50
60 70 80 90 100 110
pF1KE5 HLALGQLWTLCRQWLRPEARSKEQMLELLVLEQFLGALPSKMRTWVQSQGPRSCREAASL
. ::.:: :::::::::.:::::::::::::::::::: .... ::.: : : .:::.:
NP_932 QEALAQLRELCRQWLRPEVRSKEQMLELLVLEQFLGALPPEIQARVQGQRPGSPEEAAAL
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE5 VEDLTQMCQQEGERRRLRAPGRARGPDVSEDRTALLPAHIAPTPARPLPTSKPLLPRGCV
:. : . . : :: . . ...: .: .. . :. . : : :: .:
NP_932 VDGLRR--EPGGPRRWVTV--QVQGQEVLSEK--MEPSSFQPLPETEPPTPEPGPKTPPR
120 130 140 150 160 170
pF1KE5 FNYFYI
NP_932 TMQESPLGLQVKEESEVTEDSDFLESGPLAATQESVPTLLPEEAQRCGTVLDQIFPHSKT
180 190 200 210 220 230
>>NP_003413 (OMIM: 194550) myeloid zinc finger 1 isoform (734 aa)
initn: 379 init1: 351 opt: 409 Z-score: 386.4 bits: 80.1 E(85289): 8.7e-15
Smith-Waterman score: 409; 45.9% identity (66.5% similar) in 170 aa overlap (4-165:2-165)
10 20 30 40 50
pF1KE5 MLPRPKAPASPRR--PQTPTPS----EQDADPGPASPRDT--EAQRLRFRQFQYHVASGP
:: . .:: : :. : :.. . : :. : :: ::::: :.:. :.::
NP_003 MRPAVLGSPDRAPPEDEGPVMVKLEDSEEEGEAALWDPGPEAARLRFRCFRYEEATGP
10 20 30 40 50
60 70 80 90 100 110
pF1KE5 HLALGQLWTLCRQWLRPEARSKEQMLELLVLEQFLGALPSKMRTWVQSQGPRSCREAASL
. ::.:: :::::::::.:::::::::::::::::::: .... ::.: : : .:::.:
NP_003 QEALAQLRELCRQWLRPEVRSKEQMLELLVLEQFLGALPPEIQARVQGQRPGSPEEAAAL
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE5 VEDLTQMCQQEGERRRLRAPGRARGPDVSEDRTALLPAHIAPTPARPLPTSKPLLPRGCV
:. : . . : :: . . ...: .: .. . :. . : : :: .:
NP_003 VDGLRR--EPGGPRRWVTV--QVQGQEVLSEK--MEPSSFQPLPETEPPTPEPGPKTPPR
120 130 140 150 160 170
pF1KE5 FNYFYI
NP_003 TMQESPLGLQVKEESEVTEDSDFLESGPLAATQESVPTLLPEEAQRCGTVLDQIFPHSKT
180 190 200 210 220 230
178 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 23:28:46 2016 done: Mon Nov 7 23:28:47 2016
Total Scan time: 5.570 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]