Result of FASTA (omim) for
pFN21AE5286
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5286, 232 aa
1>>>pF1KE5286 232 - 232 aa - 232 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.5639+/-0.000302; mu= 12.7998+/- 0.019
mean_var=73.2331+/-15.353, 0's: 0 Z-trim(117.5): 67 B-trim: 239 in 1/59
Lambda= 0.149872
statistics sampled from 29518 (29586) to 29518 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.734), E-opt: 0.2 (0.347), width: 16
Scan time: 5.100
The best scores are: opt bits E(85289)
NP_001002914 (OMIM: 609848) BTB/POZ domain-contain ( 232) 1592 353.0 2.5e-97
NP_001161433 (OMIM: 611725,611726) BTB/POZ domain- ( 288) 194 50.8 3e-06
NP_694578 (OMIM: 611725,611726) BTB/POZ domain-con ( 289) 194 50.8 3e-06
NP_001245150 (OMIM: 181270,613420) BTB/POZ domain- ( 257) 190 49.9 5e-06
NP_001129677 (OMIM: 181270,613420) BTB/POZ domain- ( 257) 190 49.9 5e-06
XP_016881197 (OMIM: 181270,613420) PREDICTED: BTB/ ( 257) 190 49.9 5e-06
NP_945342 (OMIM: 181270,613420) BTB/POZ domain-con ( 257) 190 49.9 5e-06
NP_001245151 (OMIM: 181270,613420) BTB/POZ domain- ( 265) 190 49.9 5.1e-06
NP_076981 (OMIM: 615240) BTB/POZ domain-containing ( 234) 189 49.6 5.3e-06
XP_016882772 (OMIM: 615240) PREDICTED: BTB/POZ dom ( 283) 189 49.7 6.3e-06
NP_001123466 (OMIM: 615240) BTB/POZ domain-contain ( 283) 189 49.7 6.3e-06
XP_011525600 (OMIM: 615240) PREDICTED: BTB/POZ dom ( 283) 189 49.7 6.3e-06
XP_011525599 (OMIM: 615240) PREDICTED: BTB/POZ dom ( 283) 189 49.7 6.3e-06
NP_001123467 (OMIM: 615240) BTB/POZ domain-contain ( 283) 189 49.7 6.3e-06
NP_001136202 (OMIM: 181270,613420) BTB/POZ domain- ( 865) 190 50.2 1.4e-05
XP_011535975 (OMIM: 613423) PREDICTED: BTB/POZ dom ( 286) 160 43.4 0.00049
XP_011535974 (OMIM: 613423) PREDICTED: BTB/POZ dom ( 304) 160 43.4 0.00051
NP_612453 (OMIM: 610521) BTB/POZ domain-containing ( 325) 159 43.2 0.00063
NP_955751 (OMIM: 607947) potassium channel regulat ( 229) 157 42.7 0.00063
XP_011535973 (OMIM: 613423) PREDICTED: BTB/POZ dom ( 428) 160 43.5 0.00068
XP_005268549 (OMIM: 613423) PREDICTED: BTB/POZ dom ( 428) 160 43.5 0.00068
XP_005268550 (OMIM: 613423) PREDICTED: BTB/POZ dom ( 428) 160 43.5 0.00068
XP_006714852 (OMIM: 613423) PREDICTED: BTB/POZ dom ( 428) 160 43.5 0.00068
NP_065819 (OMIM: 613423) BTB/POZ domain-containing ( 428) 160 43.5 0.00068
NP_775876 (OMIM: 607947) potassium channel regulat ( 272) 157 42.7 0.00073
NP_001269615 (OMIM: 616386,616398) BTB/POZ domain- ( 220) 144 39.9 0.0043
NP_001269614 (OMIM: 616386,616398) BTB/POZ domain- ( 225) 144 39.9 0.0044
XP_011528679 (OMIM: 616386,616398) PREDICTED: BTB/ ( 249) 144 39.9 0.0048
NP_001306223 (OMIM: 613272) BTB/POZ domain-contain ( 813) 150 41.5 0.0052
NP_057205 (OMIM: 613272) BTB/POZ domain-containing ( 815) 150 41.5 0.0052
NP_078957 (OMIM: 616386,616398) BTB/POZ domain-con ( 297) 144 40.0 0.0055
XP_005261801 (OMIM: 616386,616398) PREDICTED: BTB/ ( 315) 144 40.0 0.0058
NP_001269613 (OMIM: 616386,616398) BTB/POZ domain- ( 321) 144 40.0 0.0059
XP_005261800 (OMIM: 616386,616398) PREDICTED: BTB/ ( 328) 144 40.0 0.006
XP_005261799 (OMIM: 616386,616398) PREDICTED: BTB/ ( 352) 144 40.0 0.0064
XP_005261798 (OMIM: 616386,616398) PREDICTED: BTB/ ( 352) 144 40.0 0.0064
XP_011528676 (OMIM: 616386,616398) PREDICTED: BTB/ ( 370) 144 40.0 0.0066
XP_016878595 (OMIM: 608947) PREDICTED: BTB/POZ dom ( 173) 139 38.7 0.0075
>>NP_001002914 (OMIM: 609848) BTB/POZ domain-containing (232 aa)
initn: 1592 init1: 1592 opt: 1592 Z-score: 1868.2 bits: 353.0 E(85289): 2.5e-97
Smith-Waterman score: 1592; 100.0% identity (100.0% similar) in 232 aa overlap (1-232:1-232)
10 20 30 40 50 60
pF1KE5 MLGAMFRAGTPMPPNLNSQGGGHYFIDRDGKAFRHILNFLRLGRLDLPRGYGETALLRAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLGAMFRAGTPMPPNLNSQGGGHYFIDRDGKAFRHILNFLRLGRLDLPRGYGETALLRAE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 ADFYQIRPLLDALRELEASQGTPAPTAALLHADVDVSPRLVHFSARRGPHHYELSSVQVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ADFYQIRPLLDALRELEASQGTPAPTAALLHADVDVSPRLVHFSARRGPHHYELSSVQVD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 TFRANLFCTDSECLGALRARFGVASGDRAEGSPHFHLEWAPRPVELPEVEYGRLGLQPLW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TFRANLFCTDSECLGALRARFGVASGDRAEGSPHFHLEWAPRPVELPEVEYGRLGLQPLW
130 140 150 160 170 180
190 200 210 220 230
pF1KE5 TGGPGERREVVGTPSFLEEVLRVALEHGFRLDSVFPDPEDLLNSRSLRFVRH
::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TGGPGERREVVGTPSFLEEVLRVALEHGFRLDSVFPDPEDLLNSRSLRFVRH
190 200 210 220 230
>>NP_001161433 (OMIM: 611725,611726) BTB/POZ domain-cont (288 aa)
initn: 170 init1: 105 opt: 194 Z-score: 233.2 bits: 50.8 E(85289): 3e-06
Smith-Waterman score: 194; 31.9% identity (61.4% similar) in 166 aa overlap (1-161:76-234)
10 20 30
pF1KE5 MLGAMFRAGTPMPPNLNSQGGGHYFIDRDG
::.::: .: . :. .:.: .:::::::
NP_001 PQEFPEVVPLNIGGAHFTTRLSTLRCYEDTMLAAMF-SGRHYIPT-DSEG--RYFIDRDG
50 60 70 80 90 100
40 50 60 70 80
pF1KE5 KAFRHILNFLRLGRLDLPRGYGETALLRAEADFYQIRPLLDALRELEASQGTPAPTA--A
: .::::: : ::: :. . ::..: : :::. :.... .: . : .
NP_001 THFGDVLNFLRSG--DLPPRERVRAVYK-EAQYYAIGPLLEQLENMQPLKGEKVRQAFLG
110 120 130 140 150
90 100 110 120 130 140
pF1KE5 LLHADVDVSPRLVHFSARRG-PHHYELSSVQVDTFRANLFCTDSEC--LGALRARFGVAS
:. : :.:... :. .. ......: .:. .. : :: :..:: . . ..
NP_001 LMPYYKDHLERIVEIARLRAVQRKARFAKLKVCVFKEEMPITPYECPLLNSLRFERSESD
160 170 180 190 200 210
150 160 170 180 190 200
pF1KE5 GDRAEGSPHFHLEWAPRPVELPEVEYGRLGLQPLWTGGPGERREVVGTPSFLEEVLRVAL
:. : . . ..:
NP_001 GQLFEHHCEVDVSFGPWEAVADVYDLLHCLVTDLSAQGLTVDHQCIGVCDKHLVNHYYCK
220 230 240 250 260 270
>>NP_694578 (OMIM: 611725,611726) BTB/POZ domain-contain (289 aa)
initn: 170 init1: 105 opt: 194 Z-score: 233.2 bits: 50.8 E(85289): 3e-06
Smith-Waterman score: 194; 31.9% identity (61.4% similar) in 166 aa overlap (1-161:76-234)
10 20 30
pF1KE5 MLGAMFRAGTPMPPNLNSQGGGHYFIDRDG
::.::: .: . :. .:.: .:::::::
NP_694 PQEFPEVVPLNIGGAHFTTRLSTLRCYEDTMLAAMF-SGRHYIPT-DSEG--RYFIDRDG
50 60 70 80 90 100
40 50 60 70 80
pF1KE5 KAFRHILNFLRLGRLDLPRGYGETALLRAEADFYQIRPLLDALRELEASQGTPAPTA--A
: .::::: : ::: :. . ::..: : :::. :.... .: . : .
NP_694 THFGDVLNFLRSG--DLPPRERVRAVYK-EAQYYAIGPLLEQLENMQPLKGEKVRQAFLG
110 120 130 140 150
90 100 110 120 130 140
pF1KE5 LLHADVDVSPRLVHFSARRG-PHHYELSSVQVDTFRANLFCTDSEC--LGALRARFGVAS
:. : :.:... :. .. ......: .:. .. : :: :..:: . . ..
NP_694 LMPYYKDHLERIVEIARLRAVQRKARFAKLKVCVFKEEMPITPYECPLLNSLRFERSESD
160 170 180 190 200 210
150 160 170 180 190 200
pF1KE5 GDRAEGSPHFHLEWAPRPVELPEVEYGRLGLQPLWTGGPGERREVVGTPSFLEEVLRVAL
:. : . . ..:
NP_694 GQLFEHHCEVDVSFGPWEAVADVYDLLHCLVTDLSAQGLTVDHQCIGVCDKHLVNHYYCK
220 230 240 250 260 270
>>NP_001245150 (OMIM: 181270,613420) BTB/POZ domain-cont (257 aa)
initn: 218 init1: 185 opt: 190 Z-score: 229.2 bits: 49.9 E(85289): 5e-06
Smith-Waterman score: 190; 42.0% identity (69.6% similar) in 69 aa overlap (2-70:56-121)
10 20 30
pF1KE5 MLGAMFRAGTPMPPNLNSQGGGHYFIDRDGK
.: .: . :. . .: ::::::::.
NP_001 TKSNAPVHIDVGGHMYTSSLATLTKYPESRIGRLFDGTEPIVLDSLKQ---HYFIDRDGQ
30 40 50 60 70 80
40 50 60 70 80 90
pF1KE5 AFRHILNFLRLGRLDLPRGYGETALLRAEADFYQIRPLLDALRELEASQGTPAPTAALLH
::.:::::: ..: .: . . .:: :: ..:..:.:
NP_001 MFRYILNFLRTSKLLIPDDFKDYTLLYEEAKYFQLQPMLLEMERWKQDRETGRFSRPCEC
90 100 110 120 130 140
100 110 120 130 140 150
pF1KE5 ADVDVSPRLVHFSARRGPHHYELSSVQVDTFRANLFCTDSECLGALRARFGVASGDRAEG
NP_001 LVVRVAPDLGERITLSGDKSLIEEVFPEIGDVMCNSVNAGWNHDSTHVIRFPLNGYCHLN
150 160 170 180 190 200
>>NP_001129677 (OMIM: 181270,613420) BTB/POZ domain-cont (257 aa)
initn: 218 init1: 185 opt: 190 Z-score: 229.2 bits: 49.9 E(85289): 5e-06
Smith-Waterman score: 190; 42.0% identity (69.6% similar) in 69 aa overlap (2-70:56-121)
10 20 30
pF1KE5 MLGAMFRAGTPMPPNLNSQGGGHYFIDRDGK
.: .: . :. . .: ::::::::.
NP_001 TKSNAPVHIDVGGHMYTSSLATLTKYPESRIGRLFDGTEPIVLDSLKQ---HYFIDRDGQ
30 40 50 60 70 80
40 50 60 70 80 90
pF1KE5 AFRHILNFLRLGRLDLPRGYGETALLRAEADFYQIRPLLDALRELEASQGTPAPTAALLH
::.:::::: ..: .: . . .:: :: ..:..:.:
NP_001 MFRYILNFLRTSKLLIPDDFKDYTLLYEEAKYFQLQPMLLEMERWKQDRETGRFSRPCEC
90 100 110 120 130 140
100 110 120 130 140 150
pF1KE5 ADVDVSPRLVHFSARRGPHHYELSSVQVDTFRANLFCTDSECLGALRARFGVASGDRAEG
NP_001 LVVRVAPDLGERITLSGDKSLIEEVFPEIGDVMCNSVNAGWNHDSTHVIRFPLNGYCHLN
150 160 170 180 190 200
>>XP_016881197 (OMIM: 181270,613420) PREDICTED: BTB/POZ (257 aa)
initn: 218 init1: 185 opt: 190 Z-score: 229.2 bits: 49.9 E(85289): 5e-06
Smith-Waterman score: 190; 42.0% identity (69.6% similar) in 69 aa overlap (2-70:56-121)
10 20 30
pF1KE5 MLGAMFRAGTPMPPNLNSQGGGHYFIDRDGK
.: .: . :. . .: ::::::::.
XP_016 TKSNAPVHIDVGGHMYTSSLATLTKYPESRIGRLFDGTEPIVLDSLKQ---HYFIDRDGQ
30 40 50 60 70 80
40 50 60 70 80 90
pF1KE5 AFRHILNFLRLGRLDLPRGYGETALLRAEADFYQIRPLLDALRELEASQGTPAPTAALLH
::.:::::: ..: .: . . .:: :: ..:..:.:
XP_016 MFRYILNFLRTSKLLIPDDFKDYTLLYEEAKYFQLQPMLLEMERWKQDRETGRFSRPCEC
90 100 110 120 130 140
100 110 120 130 140 150
pF1KE5 ADVDVSPRLVHFSARRGPHHYELSSVQVDTFRANLFCTDSECLGALRARFGVASGDRAEG
XP_016 LVVRVAPDLGERITLSGDKSLIEEVFPEIGDVMCNSVNAGWNHDSTHVIRFPLNGYCHLN
150 160 170 180 190 200
>>NP_945342 (OMIM: 181270,613420) BTB/POZ domain-contain (257 aa)
initn: 218 init1: 185 opt: 190 Z-score: 229.2 bits: 49.9 E(85289): 5e-06
Smith-Waterman score: 190; 42.0% identity (69.6% similar) in 69 aa overlap (2-70:56-121)
10 20 30
pF1KE5 MLGAMFRAGTPMPPNLNSQGGGHYFIDRDGK
.: .: . :. . .: ::::::::.
NP_945 TKSNAPVHIDVGGHMYTSSLATLTKYPESRIGRLFDGTEPIVLDSLKQ---HYFIDRDGQ
30 40 50 60 70 80
40 50 60 70 80 90
pF1KE5 AFRHILNFLRLGRLDLPRGYGETALLRAEADFYQIRPLLDALRELEASQGTPAPTAALLH
::.:::::: ..: .: . . .:: :: ..:..:.:
NP_945 MFRYILNFLRTSKLLIPDDFKDYTLLYEEAKYFQLQPMLLEMERWKQDRETGRFSRPCEC
90 100 110 120 130 140
100 110 120 130 140 150
pF1KE5 ADVDVSPRLVHFSARRGPHHYELSSVQVDTFRANLFCTDSECLGALRARFGVASGDRAEG
NP_945 LVVRVAPDLGERITLSGDKSLIEEVFPEIGDVMCNSVNAGWNHDSTHVIRFPLNGYCHLN
150 160 170 180 190 200
>>NP_001245151 (OMIM: 181270,613420) BTB/POZ domain-cont (265 aa)
initn: 218 init1: 185 opt: 190 Z-score: 229.0 bits: 49.9 E(85289): 5.1e-06
Smith-Waterman score: 190; 42.0% identity (69.6% similar) in 69 aa overlap (2-70:64-129)
10 20 30
pF1KE5 MLGAMFRAGTPMPPNLNSQGGGHYFIDRDGK
.: .: . :. . .: ::::::::.
NP_001 TKSNAPVHIDVGGHMYTSSLATLTKYPESRIGRLFDGTEPIVLDSLKQ---HYFIDRDGQ
40 50 60 70 80 90
40 50 60 70 80 90
pF1KE5 AFRHILNFLRLGRLDLPRGYGETALLRAEADFYQIRPLLDALRELEASQGTPAPTAALLH
::.:::::: ..: .: . . .:: :: ..:..:.:
NP_001 MFRYILNFLRTSKLLIPDDFKDYTLLYEEAKYFQLQPMLLEMERWKQDRETGRFSRPCEC
100 110 120 130 140 150
100 110 120 130 140 150
pF1KE5 ADVDVSPRLVHFSARRGPHHYELSSVQVDTFRANLFCTDSECLGALRARFGVASGDRAEG
NP_001 LVVRVAPDLGERITLSGDKSLIEEVFPEIGDVMCNSVNAGWNHDSTHVIRFPLNGYCHLN
160 170 180 190 200 210
>>NP_076981 (OMIM: 615240) BTB/POZ domain-containing pro (234 aa)
initn: 251 init1: 187 opt: 189 Z-score: 228.7 bits: 49.6 E(85289): 5.3e-06
Smith-Waterman score: 189; 50.0% identity (74.1% similar) in 58 aa overlap (23-80:100-154)
10 20 30 40 50
pF1KE5 MLGAMFRAGTPMPPNLNSQGGGHYFIDRDGKAFRHILNFLRLGRLDLPRGYG
::::::::. ::..:.::: ..: :: .
NP_076 SLATLTKYPDSRISRLFNGTEPIVLDSLKQHYFIDRDGEIFRYVLSFLRTSKLLLPDDFK
70 80 90 100 110 120
60 70 80 90 100 110
pF1KE5 ETALLRAEADFYQIRPLLDALRELEASQGTPAPTAALLHADVDVSPRLVHFSARRGPHHY
. .:: :: .::..:. .:::: :
NP_076 DFSLLYEEARYYQLQPM---VRELERWQQEQEQRRRSRACDCLVVRVTPDLGERIALSGE
130 140 150 160 170 180
>>XP_016882772 (OMIM: 615240) PREDICTED: BTB/POZ domain- (283 aa)
initn: 216 init1: 187 opt: 189 Z-score: 227.4 bits: 49.7 E(85289): 6.3e-06
Smith-Waterman score: 189; 50.0% identity (74.1% similar) in 58 aa overlap (23-80:100-154)
10 20 30 40 50
pF1KE5 MLGAMFRAGTPMPPNLNSQGGGHYFIDRDGKAFRHILNFLRLGRLDLPRGYG
::::::::. ::..:.::: ..: :: .
XP_016 SLATLTKYPDSRISRLFNGTEPIVLDSLKQHYFIDRDGEIFRYVLSFLRTSKLLLPDDFK
70 80 90 100 110 120
60 70 80 90 100 110
pF1KE5 ETALLRAEADFYQIRPLLDALRELEASQGTPAPTAALLHADVDVSPRLVHFSARRGPHHY
. .:: :: .::..:. .:::: :
XP_016 DFSLLYEEARYYQLQPM---VRELERWQQEQEQRRRSRACDCLVVRVTPDLGERIALSGE
130 140 150 160 170 180
232 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 23:25:51 2016 done: Mon Nov 7 23:25:52 2016
Total Scan time: 5.100 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]