FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE5284, 210 aa
  1>>>pF1KE5284 210 - 210 aa - 210 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.3405+/-0.000329; mu= 10.2904+/- 0.021
 mean_var=115.2644+/-23.159, 0's: 0 Z-trim(118.6): 11  B-trim: 382 in 1/50
 Lambda= 0.119461
 statistics sampled from 31780 (31791) to 31780 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.728), E-opt: 0.2 (0.373), width:  16
 Scan time:  5.890

The best scores are:                                      opt bits E(85289)
NP_000354 (OMIM: 115210,191044,611880,613286,61369 ( 210) 1344 241.7 6.5e-64
NP_003272 (OMIM: 191042) troponin I, slow skeletal ( 187)  716 133.4 2.3e-31
NP_001139313 (OMIM: 191043,601680) troponin I, fas ( 182)  682 127.6 1.3e-29
NP_001139301 (OMIM: 191043,601680) troponin I, fas ( 182)  677 126.7 2.4e-29
NP_003273 (OMIM: 191043,601680) troponin I, fast s ( 182)  677 126.7 2.4e-29


>>NP_000354 (OMIM: 115210,191044,611880,613286,613690) t  (210 aa)
 initn: 1344 init1: 1344 opt: 1344  Z-score: 1268.4  bits: 241.7 E(85289): 6.5e-64
Smith-Waterman score: 1344; 100.0% identity (100.0% similar) in 210 aa overlap (1-210:1-210)

               10        20        30        40        50        60
pF1KE5 MADGSSDAAREPRPAPAPIRRRSSNYRAYATEPHAKKKSKISASRKLQLKTLLLQIAKQE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MADGSSDAAREPRPAPAPIRRRSSNYRAYATEPHAKKKSKISASRKLQLKTLLLQIAKQE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE5 LEREAEERRGEKGRALSTRCQPLELAGLGFAELQDLCRQLHARVDKVDEERYDIEAKVTK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LEREAEERRGEKGRALSTRCQPLELAGLGFAELQDLCRQLHARVDKVDEERYDIEAKVTK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE5 NITEIADLTQKIFDLRGKFKRPTLRRVRISADAMMQALLGARAKESLDLRAHLKQVKKED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 NITEIADLTQKIFDLRGKFKRPTLRRVRISADAMMQALLGARAKESLDLRAHLKQVKKED
              130       140       150       160       170       180

              190       200       210
pF1KE5 TEKENREVGDWRKNIDALSGMEGRKKKFES
       ::::::::::::::::::::::::::::::
NP_000 TEKENREVGDWRKNIDALSGMEGRKKKFES
              190       200       210

>>NP_003272 (OMIM: 191042) troponin I, slow skeletal mus  (187 aa)
 initn: 718 init1: 594 opt: 716  Z-score: 684.1  bits: 133.4 E(85289): 2.3e-31
Smith-Waterman score: 716; 63.1% identity (82.7% similar) in 179 aa overlap (33-210:2-180)

             10        20        30        40        50        60  
pF1KE5 DGSSDAAREPRPAPAPIRRRSSNYRAYATEPHAKKKSKISASRKLQLKTLLLQIAKQELE
                                     :....: ::.::::: ::.:.:  ::.  :
NP_003                              MPEVERKPKITASRKLLLKSLMLAKAKECWE
                                            10        20        30 

             70        80        90       100       110       120  
pF1KE5 REAEERRGEKGRALSTRCQPLELAGLGFAELQDLCRQLHARVDKVDEERYDIEAKVTKNI
       .: :::..:: : :. :   :.  ::... ::::::.:::.:. :::::::::::  .: 
NP_003 QEHEEREAEKVRYLAERIPTLQTRGLSLSALQDLCRELHAKVEVVDEERYDIEAKCLHNT
              40        50        60        70        80        90 

            130       140       150       160       170       180  
pF1KE5 TEIADLTQKIFDLRGKFKRPTLRRVRISADAMMQALLGARAKESLDLRAHLKQVKKEDTE
        :: ::  :..::::::::: :::::.:::::..::::.. : :.::::.::.:::::::
NP_003 REIKDLKLKVMDLRGKFKRPPLRRVRVSADAMLRALLGSKHKVSMDLRANLKSVKKEDTE
             100       110       120       130       140       150 

             190       200       210       
pF1KE5 KENR-EVGDWRKNIDALSGMEGRKKKFES       
       ::   ::::::::..:.:::::::: :..       
NP_003 KERPVEVGDWRKNVEAMSGMEGRKKMFDAAKSPTSQ
             160       170       180       

>>NP_001139313 (OMIM: 191043,601680) troponin I, fast sk  (182 aa)
 initn: 557 init1: 430 opt: 682  Z-score: 652.6  bits: 127.6 E(85289): 1.3e-29
Smith-Waterman score: 682; 57.6% identity (83.6% similar) in 177 aa overlap (36-210:5-180)

          10        20        30        40        50        60     
pF1KE5 SDAAREPRPAPAPIRRRSSNYRAYATEPHAKKKSKISASRKLQLKTLLLQIAKQELEREA
                                     ::...  ..:. .::...::::  :::.: 
NP_001                           MSQCKKRNRAITARRQHLKSVMLQIAATELEKEE
                                         10        20        30    

          70        80        90       100       110       120     
pF1KE5 EERRGEKGRALSTRCQPLELAGLGFAELQDLCRQLHARVDKVDEERYDIEAKVTKNITEI
        .:..::   :. .: ::.. : ...:.:.::.::::..: ..::.::.:..: :.  :.
NP_001 SRREAEKQNYLAEHCPPLHIPG-SMSEVQELCKQLHAKIDAAEEEKYDMEVRVQKTSKEL
           40        50         60        70        80        90   

         130       140       150       160       170       180     
pF1KE5 ADLTQKIFDLRGKFKRPTLRRVRISADAMMQALLGARAKESLDLRAHLKQVKKEDTEKEN
        :..::.:::::::::: :::::.:::::..::::.. :  .::::.:::::::::::: 
NP_001 EDMNQKLFDLRGKFKRPPLRRVRMSADAMLKALLGSKHKVCMDLRANLKQVKKEDTEKER
           100       110       120       130       140       150   

           190       200       210  
pF1KE5 --REVGDWRKNIDALSGMEGRKKKFES  
         :.::::::::.  :::::::: :::  
NP_001 DLRDVGDWRKNIEEKSGMEGRKKMFESES
           160       170       180  

>>NP_001139301 (OMIM: 191043,601680) troponin I, fast sk  (182 aa)
 initn: 532 init1: 430 opt: 677  Z-score: 648.0  bits: 126.7 E(85289): 2.4e-29
Smith-Waterman score: 677; 57.1% identity (83.6% similar) in 177 aa overlap (36-210:5-180)

          10        20        30        40        50        60     
pF1KE5 SDAAREPRPAPAPIRRRSSNYRAYATEPHAKKKSKISASRKLQLKTLLLQIAKQELEREA
                                     .:...  ..:. .::...::::  :::.: 
NP_001                           MGDEEKRNRAITARRQHLKSVMLQIAATELEKEE
                                         10        20        30    

          70        80        90       100       110       120     
pF1KE5 EERRGEKGRALSTRCQPLELAGLGFAELQDLCRQLHARVDKVDEERYDIEAKVTKNITEI
        .:..::   :. .: ::.. : ...:.:.::.::::..: ..::.::.:..: :.  :.
NP_001 SRREAEKQNYLAEHCPPLHIPG-SMSEVQELCKQLHAKIDAAEEEKYDMEVRVQKTSKEL
           40        50         60        70        80        90   

         130       140       150       160       170       180     
pF1KE5 ADLTQKIFDLRGKFKRPTLRRVRISADAMMQALLGARAKESLDLRAHLKQVKKEDTEKEN
        :..::.:::::::::: :::::.:::::..::::.. :  .::::.:::::::::::: 
NP_001 EDMNQKLFDLRGKFKRPPLRRVRMSADAMLKALLGSKHKVCMDLRANLKQVKKEDTEKER
           100       110       120       130       140       150   

           190       200       210  
pF1KE5 --REVGDWRKNIDALSGMEGRKKKFES  
         :.::::::::.  :::::::: :::  
NP_001 DLRDVGDWRKNIEEKSGMEGRKKMFESES
           160       170       180  

>>NP_003273 (OMIM: 191043,601680) troponin I, fast skele  (182 aa)
 initn: 532 init1: 430 opt: 677  Z-score: 648.0  bits: 126.7 E(85289): 2.4e-29
Smith-Waterman score: 677; 57.1% identity (83.6% similar) in 177 aa overlap (36-210:5-180)

          10        20        30        40        50        60     
pF1KE5 SDAAREPRPAPAPIRRRSSNYRAYATEPHAKKKSKISASRKLQLKTLLLQIAKQELEREA
                                     .:...  ..:. .::...::::  :::.: 
NP_003                           MGDEEKRNRAITARRQHLKSVMLQIAATELEKEE
                                         10        20        30    

          70        80        90       100       110       120     
pF1KE5 EERRGEKGRALSTRCQPLELAGLGFAELQDLCRQLHARVDKVDEERYDIEAKVTKNITEI
        .:..::   :. .: ::.. : ...:.:.::.::::..: ..::.::.:..: :.  :.
NP_003 SRREAEKQNYLAEHCPPLHIPG-SMSEVQELCKQLHAKIDAAEEEKYDMEVRVQKTSKEL
           40        50         60        70        80        90   

         130       140       150       160       170       180     
pF1KE5 ADLTQKIFDLRGKFKRPTLRRVRISADAMMQALLGARAKESLDLRAHLKQVKKEDTEKEN
        :..::.:::::::::: :::::.:::::..::::.. :  .::::.:::::::::::: 
NP_003 EDMNQKLFDLRGKFKRPPLRRVRMSADAMLKALLGSKHKVCMDLRANLKQVKKEDTEKER
           100       110       120       130       140       150   

           190       200       210  
pF1KE5 --REVGDWRKNIDALSGMEGRKKKFES  
         :.::::::::.  :::::::: :::  
NP_003 DLRDVGDWRKNIEEKSGMEGRKKMFESES
           160       170       180  




210 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Mon Nov  7 23:24:47 2016 done: Mon Nov  7 23:24:48 2016
 Total Scan time:  5.890 Total Display time: -0.020

Function used was FASTA [36.3.4 Apr, 2011]