Result of FASTA (omim) for
pFN21AE5279
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5279, 238 aa
1>>>pF1KE5279 238 - 238 aa - 238 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.0410+/-0.000343; mu= 7.2947+/- 0.022
mean_var=129.3610+/-25.307, 0's: 0 Z-trim(117.4): 44 B-trim: 0 in 0/58
Lambda= 0.112765
statistics sampled from 29348 (29392) to 29348 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.701), E-opt: 0.2 (0.345), width: 16
Scan time: 5.790
The best scores are: opt bits E(85289)
NP_005862 (OMIM: 603519) survival of motor neuron- ( 238) 1544 261.9 7e-70
XP_005269439 (OMIM: 603519) PREDICTED: survival of ( 199) 1301 222.3 4.9e-58
NP_075015 (OMIM: 253400,601627) survival motor neu ( 250) 191 41.8 0.0013
XP_016865275 (OMIM: 253300,253400,253550,271150,60 ( 250) 191 41.8 0.0013
NP_075012 (OMIM: 253300,253400,253550,271150,60035 ( 262) 191 41.8 0.0014
NP_075014 (OMIM: 253400,601627) survival motor neu ( 262) 191 41.8 0.0014
NP_075013 (OMIM: 253400,601627) survival motor neu ( 282) 191 41.8 0.0015
NP_001284644 (OMIM: 253300,253400,253550,271150,60 ( 282) 191 41.8 0.0015
XP_016865276 (OMIM: 253400,601627) PREDICTED: surv ( 290) 191 41.8 0.0015
XP_011541901 (OMIM: 253400,601627) PREDICTED: surv ( 294) 191 41.8 0.0015
XP_011541898 (OMIM: 253300,253400,253550,271150,60 ( 294) 191 41.8 0.0015
NP_059107 (OMIM: 253400,601627) survival motor neu ( 294) 191 41.8 0.0015
NP_000335 (OMIM: 253300,253400,253550,271150,60035 ( 294) 191 41.8 0.0015
>>NP_005862 (OMIM: 603519) survival of motor neuron-rela (238 aa)
initn: 1544 init1: 1544 opt: 1544 Z-score: 1375.5 bits: 261.9 E(85289): 7e-70
Smith-Waterman score: 1544; 100.0% identity (100.0% similar) in 238 aa overlap (1-238:1-238)
10 20 30 40 50 60
pF1KE5 MSEDLAKQLASYKAQLQQVEAALSGNGENEDLLKLKKDLQEVIELTKDLLSTQPSETLAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MSEDLAKQLASYKAQLQQVEAALSGNGENEDLLKLKKDLQEVIELTKDLLSTQPSETLAS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 SDSFASTQPTHSWKVGDKCMAVWSEDGQCYEAEIEEIDEENGTAAITFAGYGNAEVTPLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 SDSFASTQPTHSWKVGDKCMAVWSEDGQCYEAEIEEIDEENGTAAITFAGYGNAEVTPLL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 NLKPVEEGRKAKEDSGNKPMSKKEMIAQQREYKKKKALKKAQRIKELEQEREDQKVKWQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 NLKPVEEGRKAKEDSGNKPMSKKEMIAQQREYKKKKALKKAQRIKELEQEREDQKVKWQQ
130 140 150 160 170 180
190 200 210 220 230
pF1KE5 FNNRAYSKNKKGQVKRSIFASPESVTGKVGVGTCGIADKPMTQYQDTSKYNVRHLMPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 FNNRAYSKNKKGQVKRSIFASPESVTGKVGVGTCGIADKPMTQYQDTSKYNVRHLMPQ
190 200 210 220 230
>>XP_005269439 (OMIM: 603519) PREDICTED: survival of mot (199 aa)
initn: 1301 init1: 1301 opt: 1301 Z-score: 1163.0 bits: 222.3 E(85289): 4.9e-58
Smith-Waterman score: 1301; 100.0% identity (100.0% similar) in 198 aa overlap (41-238:2-199)
20 30 40 50 60 70
pF1KE5 SYKAQLQQVEAALSGNGENEDLLKLKKDLQEVIELTKDLLSTQPSETLASSDSFASTQPT
::::::::::::::::::::::::::::::
XP_005 MEVIELTKDLLSTQPSETLASSDSFASTQPT
10 20 30
80 90 100 110 120 130
pF1KE5 HSWKVGDKCMAVWSEDGQCYEAEIEEIDEENGTAAITFAGYGNAEVTPLLNLKPVEEGRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HSWKVGDKCMAVWSEDGQCYEAEIEEIDEENGTAAITFAGYGNAEVTPLLNLKPVEEGRK
40 50 60 70 80 90
140 150 160 170 180 190
pF1KE5 AKEDSGNKPMSKKEMIAQQREYKKKKALKKAQRIKELEQEREDQKVKWQQFNNRAYSKNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AKEDSGNKPMSKKEMIAQQREYKKKKALKKAQRIKELEQEREDQKVKWQQFNNRAYSKNK
100 110 120 130 140 150
200 210 220 230
pF1KE5 KGQVKRSIFASPESVTGKVGVGTCGIADKPMTQYQDTSKYNVRHLMPQ
::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KGQVKRSIFASPESVTGKVGVGTCGIADKPMTQYQDTSKYNVRHLMPQ
160 170 180 190
>>NP_075015 (OMIM: 253400,601627) survival motor neuron (250 aa)
initn: 177 init1: 177 opt: 191 Z-score: 185.6 bits: 41.8 E(85289): 0.0013
Smith-Waterman score: 191; 29.5% identity (63.6% similar) in 129 aa overlap (38-165:58-184)
10 20 30 40 50 60
pF1KE5 QLASYKAQLQQVEAALSGNGENEDLLKLKKDLQEVIELTKDLLSTQPSETLASSDSFAST
:. :. : . .:.. .:.. ..
NP_075 SDDSDIWDDTALIKAYDKAVASFKHALKNGDICETSGKPKTTPKRKPAKK-NKSQKKNTA
30 40 50 60 70 80
70 80 90 100 110 120
pF1KE5 QPTHSWKVGDKCMAVWSEDGQCYEAEIEEIDEENGTAAITFAGYGNAEVTPLLNL-KPVE
..::::::: :.::::: : : : :: . : .....:::: : : .: .:.
NP_075 ASLQQWKVGDKCSAIWSEDGCIYPATIASIDFKRETCVVVYTGYGNREEQNLSDLLSPIC
90 100 110 120 130 140
130 140 150 160 170 180
pF1KE5 EGRKAKEDSGNKPMSKKEMIAQQREYKKKKALKKAQRIKELEQEREDQKVKWQQFNNRAY
: . :..... ..... ... : ... . .:.. ::
NP_075 EVANNIEQNAQENENESQVSTDESENSRSPG-NKSDNIKPKSAPWNSFLPPPPPMPGPRL
150 160 170 180 190 200
190 200 210 220 230
pF1KE5 SKNKKGQVKRSIFASPESVTGKVGVGTCGIADKPMTQYQDTSKYNVRHLMPQ
NP_075 GPGKIIPPPPPICPDSLDDADALGSMLISWYMSGYHTGYYMEMLA
210 220 230 240 250
>>XP_016865275 (OMIM: 253300,253400,253550,271150,600354 (250 aa)
initn: 177 init1: 177 opt: 191 Z-score: 185.6 bits: 41.8 E(85289): 0.0013
Smith-Waterman score: 191; 29.5% identity (63.6% similar) in 129 aa overlap (38-165:58-184)
10 20 30 40 50 60
pF1KE5 QLASYKAQLQQVEAALSGNGENEDLLKLKKDLQEVIELTKDLLSTQPSETLASSDSFAST
:. :. : . .:.. .:.. ..
XP_016 SDDSDIWDDTALIKAYDKAVASFKHALKNGDICETSGKPKTTPKRKPAKK-NKSQKKNTA
30 40 50 60 70 80
70 80 90 100 110 120
pF1KE5 QPTHSWKVGDKCMAVWSEDGQCYEAEIEEIDEENGTAAITFAGYGNAEVTPLLNL-KPVE
..::::::: :.::::: : : : :: . : .....:::: : : .: .:.
XP_016 ASLQQWKVGDKCSAIWSEDGCIYPATIASIDFKRETCVVVYTGYGNREEQNLSDLLSPIC
90 100 110 120 130 140
130 140 150 160 170 180
pF1KE5 EGRKAKEDSGNKPMSKKEMIAQQREYKKKKALKKAQRIKELEQEREDQKVKWQQFNNRAY
: . :..... ..... ... : ... . .:.. ::
XP_016 EVANNIEQNAQENENESQVSTDESENSRSPG-NKSDNIKPKSAPWNSFLPPPPPMPGPRL
150 160 170 180 190 200
190 200 210 220 230
pF1KE5 SKNKKGQVKRSIFASPESVTGKVGVGTCGIADKPMTQYQDTSKYNVRHLMPQ
XP_016 GPGKIIPPPPPICPDSLDDADALGSMLISWYMSGYHTGYYMEMLA
210 220 230 240 250
>>NP_075012 (OMIM: 253300,253400,253550,271150,600354) s (262 aa)
initn: 177 init1: 177 opt: 191 Z-score: 185.4 bits: 41.8 E(85289): 0.0014
Smith-Waterman score: 191; 29.5% identity (63.6% similar) in 129 aa overlap (38-165:58-184)
10 20 30 40 50 60
pF1KE5 QLASYKAQLQQVEAALSGNGENEDLLKLKKDLQEVIELTKDLLSTQPSETLASSDSFAST
:. :. : . .:.. .:.. ..
NP_075 SDDSDIWDDTALIKAYDKAVASFKHALKNGDICETSGKPKTTPKRKPAKK-NKSQKKNTA
30 40 50 60 70 80
70 80 90 100 110 120
pF1KE5 QPTHSWKVGDKCMAVWSEDGQCYEAEIEEIDEENGTAAITFAGYGNAEVTPLLNL-KPVE
..::::::: :.::::: : : : :: . : .....:::: : : .: .:.
NP_075 ASLQQWKVGDKCSAIWSEDGCIYPATIASIDFKRETCVVVYTGYGNREEQNLSDLLSPIC
90 100 110 120 130 140
130 140 150 160 170 180
pF1KE5 EGRKAKEDSGNKPMSKKEMIAQQREYKKKKALKKAQRIKELEQEREDQKVKWQQFNNRAY
: . :..... ..... ... : ... . .:.. ::
NP_075 EVANNIEQNAQENENESQVSTDESENSRSPG-NKSDNIKPKSAPWNSFLPPPPPMPGPRL
150 160 170 180 190 200
190 200 210 220 230
pF1KE5 SKNKKGQVKRSIFASPESVTGKVGVGTCGIADKPMTQYQDTSKYNVRHLMPQ
NP_075 GPGKIIPPPPPICPDSLDDADALGSMLISWYMSGYHTGYYMGFRQNQKEGRCSHSLN
210 220 230 240 250 260
>>NP_075014 (OMIM: 253400,601627) survival motor neuron (262 aa)
initn: 177 init1: 177 opt: 191 Z-score: 185.4 bits: 41.8 E(85289): 0.0014
Smith-Waterman score: 191; 29.5% identity (63.6% similar) in 129 aa overlap (38-165:58-184)
10 20 30 40 50 60
pF1KE5 QLASYKAQLQQVEAALSGNGENEDLLKLKKDLQEVIELTKDLLSTQPSETLASSDSFAST
:. :. : . .:.. .:.. ..
NP_075 SDDSDIWDDTALIKAYDKAVASFKHALKNGDICETSGKPKTTPKRKPAKK-NKSQKKNTA
30 40 50 60 70 80
70 80 90 100 110 120
pF1KE5 QPTHSWKVGDKCMAVWSEDGQCYEAEIEEIDEENGTAAITFAGYGNAEVTPLLNL-KPVE
..::::::: :.::::: : : : :: . : .....:::: : : .: .:.
NP_075 ASLQQWKVGDKCSAIWSEDGCIYPATIASIDFKRETCVVVYTGYGNREEQNLSDLLSPIC
90 100 110 120 130 140
130 140 150 160 170 180
pF1KE5 EGRKAKEDSGNKPMSKKEMIAQQREYKKKKALKKAQRIKELEQEREDQKVKWQQFNNRAY
: . :..... ..... ... : ... . .:.. ::
NP_075 EVANNIEQNAQENENESQVSTDESENSRSPG-NKSDNIKPKSAPWNSFLPPPPPMPGPRL
150 160 170 180 190 200
190 200 210 220 230
pF1KE5 SKNKKGQVKRSIFASPESVTGKVGVGTCGIADKPMTQYQDTSKYNVRHLMPQ
NP_075 GPGKIIPPPPPICPDSLDDADALGSMLISWYMSGYHTGYYMGFRQNQKEGRCSHSLN
210 220 230 240 250 260
>>NP_075013 (OMIM: 253400,601627) survival motor neuron (282 aa)
initn: 177 init1: 177 opt: 191 Z-score: 184.9 bits: 41.8 E(85289): 0.0015
Smith-Waterman score: 191; 29.5% identity (63.6% similar) in 129 aa overlap (38-165:58-184)
10 20 30 40 50 60
pF1KE5 QLASYKAQLQQVEAALSGNGENEDLLKLKKDLQEVIELTKDLLSTQPSETLASSDSFAST
:. :. : . .:.. .:.. ..
NP_075 SDDSDIWDDTALIKAYDKAVASFKHALKNGDICETSGKPKTTPKRKPAKK-NKSQKKNTA
30 40 50 60 70 80
70 80 90 100 110 120
pF1KE5 QPTHSWKVGDKCMAVWSEDGQCYEAEIEEIDEENGTAAITFAGYGNAEVTPLLNL-KPVE
..::::::: :.::::: : : : :: . : .....:::: : : .: .:.
NP_075 ASLQQWKVGDKCSAIWSEDGCIYPATIASIDFKRETCVVVYTGYGNREEQNLSDLLSPIC
90 100 110 120 130 140
130 140 150 160 170 180
pF1KE5 EGRKAKEDSGNKPMSKKEMIAQQREYKKKKALKKAQRIKELEQEREDQKVKWQQFNNRAY
: . :..... ..... ... : ... . .:.. ::
NP_075 EVANNIEQNAQENENESQVSTDESENSRSPG-NKSDNIKPKSAPWNSFLPPPPPMPGPRL
150 160 170 180 190 200
190 200 210 220 230
pF1KE5 SKNKKGQVKRSIFASPESVTGKVGVGTCGIADKPMTQYQDTSKYNVRHLMPQ
NP_075 GPGKPGLKFNGPPPPPPPPPPHLLSCWLPPFPSGPPIIPPPPPICPDSLDDADALGSMLI
210 220 230 240 250 260
>>NP_001284644 (OMIM: 253300,253400,253550,271150,600354 (282 aa)
initn: 177 init1: 177 opt: 191 Z-score: 184.9 bits: 41.8 E(85289): 0.0015
Smith-Waterman score: 191; 29.5% identity (63.6% similar) in 129 aa overlap (38-165:58-184)
10 20 30 40 50 60
pF1KE5 QLASYKAQLQQVEAALSGNGENEDLLKLKKDLQEVIELTKDLLSTQPSETLASSDSFAST
:. :. : . .:.. .:.. ..
NP_001 SDDSDIWDDTALIKAYDKAVASFKHALKNGDICETSGKPKTTPKRKPAKK-NKSQKKNTA
30 40 50 60 70 80
70 80 90 100 110 120
pF1KE5 QPTHSWKVGDKCMAVWSEDGQCYEAEIEEIDEENGTAAITFAGYGNAEVTPLLNL-KPVE
..::::::: :.::::: : : : :: . : .....:::: : : .: .:.
NP_001 ASLQQWKVGDKCSAIWSEDGCIYPATIASIDFKRETCVVVYTGYGNREEQNLSDLLSPIC
90 100 110 120 130 140
130 140 150 160 170 180
pF1KE5 EGRKAKEDSGNKPMSKKEMIAQQREYKKKKALKKAQRIKELEQEREDQKVKWQQFNNRAY
: . :..... ..... ... : ... . .:.. ::
NP_001 EVANNIEQNAQENENESQVSTDESENSRSPG-NKSDNIKPKSAPWNSFLPPPPPMPGPRL
150 160 170 180 190 200
190 200 210 220 230
pF1KE5 SKNKKGQVKRSIFASPESVTGKVGVGTCGIADKPMTQYQDTSKYNVRHLMPQ
NP_001 GPGKPGLKFNGPPPPPPPPPPHLLSCWLPPFPSGPPIIPPPPPICPDSLDDADALGSMLI
210 220 230 240 250 260
>>XP_016865276 (OMIM: 253400,601627) PREDICTED: survival (290 aa)
initn: 177 init1: 177 opt: 191 Z-score: 184.7 bits: 41.8 E(85289): 0.0015
Smith-Waterman score: 191; 29.5% identity (63.6% similar) in 129 aa overlap (38-165:58-184)
10 20 30 40 50 60
pF1KE5 QLASYKAQLQQVEAALSGNGENEDLLKLKKDLQEVIELTKDLLSTQPSETLASSDSFAST
:. :. : . .:.. .:.. ..
XP_016 SDDSDIWDDTALIKAYDKAVASFKHALKNGDICETSGKPKTTPKRKPAKK-NKSQKKNTA
30 40 50 60 70 80
70 80 90 100 110 120
pF1KE5 QPTHSWKVGDKCMAVWSEDGQCYEAEIEEIDEENGTAAITFAGYGNAEVTPLLNL-KPVE
..::::::: :.::::: : : : :: . : .....:::: : : .: .:.
XP_016 ASLQQWKVGDKCSAIWSEDGCIYPATIASIDFKRETCVVVYTGYGNREEQNLSDLLSPIC
90 100 110 120 130 140
130 140 150 160 170 180
pF1KE5 EGRKAKEDSGNKPMSKKEMIAQQREYKKKKALKKAQRIKELEQEREDQKVKWQQFNNRAY
: . :..... ..... ... : ... . .:.. ::
XP_016 EVANNIEQNAQENENESQVSTDESENSRSPG-NKSDNIKPKSAPWNSFLPPPPPMPGPRL
150 160 170 180 190 200
190 200 210 220 230
pF1KE5 SKNKKGQVKRSIFASPESVTGKVGVGTCGIADKPMTQYQDTSKYNVRHLMPQ
XP_016 GPGKPGLKFNGPPPPPPPPPPHLLSCWLPPFPSGPPIIPPPPPICPDSLDDADALGSMLI
210 220 230 240 250 260
>>XP_011541901 (OMIM: 253400,601627) PREDICTED: survival (294 aa)
initn: 177 init1: 177 opt: 191 Z-score: 184.6 bits: 41.8 E(85289): 0.0015
Smith-Waterman score: 191; 29.5% identity (63.6% similar) in 129 aa overlap (38-165:58-184)
10 20 30 40 50 60
pF1KE5 QLASYKAQLQQVEAALSGNGENEDLLKLKKDLQEVIELTKDLLSTQPSETLASSDSFAST
:. :. : . .:.. .:.. ..
XP_011 SDDSDIWDDTALIKAYDKAVASFKHALKNGDICETSGKPKTTPKRKPAKK-NKSQKKNTA
30 40 50 60 70 80
70 80 90 100 110 120
pF1KE5 QPTHSWKVGDKCMAVWSEDGQCYEAEIEEIDEENGTAAITFAGYGNAEVTPLLNL-KPVE
..::::::: :.::::: : : : :: . : .....:::: : : .: .:.
XP_011 ASLQQWKVGDKCSAIWSEDGCIYPATIASIDFKRETCVVVYTGYGNREEQNLSDLLSPIC
90 100 110 120 130 140
130 140 150 160 170 180
pF1KE5 EGRKAKEDSGNKPMSKKEMIAQQREYKKKKALKKAQRIKELEQEREDQKVKWQQFNNRAY
: . :..... ..... ... : ... . .:.. ::
XP_011 EVANNIEQNAQENENESQVSTDESENSRSPG-NKSDNIKPKSAPWNSFLPPPPPMPGPRL
150 160 170 180 190 200
190 200 210 220 230
pF1KE5 SKNKKGQVKRSIFASPESVTGKVGVGTCGIADKPMTQYQDTSKYNVRHLMPQ
XP_011 GPGKPGLKFNGPPPPPPPPPPHLLSCWLPPFPSGPPIIPPPPPICPDSLDDADALGSMLI
210 220 230 240 250 260
238 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 23:21:59 2016 done: Mon Nov 7 23:22:00 2016
Total Scan time: 5.790 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]