Result of FASTA (ccds) for
pFN21AE5278
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5278, 235 aa
1>>>pF1KE5278 235 - 235 aa - 235 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.5630+/-0.000653; mu= 13.9876+/- 0.039
mean_var=85.9513+/-16.743, 0's: 0 Z-trim(112.5): 52 B-trim: 91 in 1/52
Lambda= 0.138340
statistics sampled from 13162 (13214) to 13162 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.786), E-opt: 0.2 (0.406), width: 16
Scan time: 2.450
The best scores are: opt bits E(32554)
CCDS13193.1 DUSP15 gene_id:128853|Hs108|chr20 ( 235) 1604 329.2 1.5e-90
CCDS82607.1 DUSP15 gene_id:128853|Hs108|chr20 ( 232) 1557 319.8 9.7e-88
CCDS82606.1 DUSP15 gene_id:128853|Hs108|chr20 ( 295) 953 199.3 2.3e-51
CCDS42862.1 DUSP15 gene_id:128853|Hs108|chr20 ( 132) 895 187.5 3.7e-48
CCDS69035.1 DUSP22 gene_id:56940|Hs108|chr6 ( 205) 687 146.1 1.6e-35
CCDS4468.1 DUSP22 gene_id:56940|Hs108|chr6 ( 184) 686 145.9 1.7e-35
CCDS13883.1 DUSP18 gene_id:150290|Hs108|chr22 ( 188) 310 70.8 6.9e-13
CCDS1528.1 DUSP10 gene_id:11221|Hs108|chr1 ( 482) 311 71.3 1.2e-12
CCDS2289.1 DUSP19 gene_id:142679|Hs108|chr2 ( 217) 306 70.1 1.3e-12
CCDS7724.1 DUSP8 gene_id:1850|Hs108|chr11 ( 625) 306 70.4 3e-12
CCDS33418.1 DUSP28 gene_id:285193|Hs108|chr2 ( 176) 298 68.4 3.4e-12
CCDS7566.1 DUSP5 gene_id:1847|Hs108|chr10 ( 384) 300 69.1 4.7e-12
CCDS8157.1 SSH3 gene_id:54961|Hs108|chr11 ( 659) 297 68.7 1.1e-11
CCDS1234.1 DUSP12 gene_id:11266|Hs108|chr1 ( 340) 292 67.4 1.3e-11
CCDS9711.1 STYX gene_id:6815|Hs108|chr14 ( 223) 287 66.3 1.9e-11
CCDS8650.1 DUSP16 gene_id:80824|Hs108|chr12 ( 665) 288 66.9 3.8e-11
>>CCDS13193.1 DUSP15 gene_id:128853|Hs108|chr20 (235 aa)
initn: 1604 init1: 1604 opt: 1604 Z-score: 1739.3 bits: 329.2 E(32554): 1.5e-90
Smith-Waterman score: 1604; 99.6% identity (100.0% similar) in 235 aa overlap (1-235:1-235)
10 20 30 40 50 60
pF1KE5 MGNGMTKVLPGLYLGNFIDAKDLDQLGRNKITHIISIHESPQPLLQDITYLRIPVADTPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 MGNGMTKVLPGLYLGNFIDAKDLDQLGRNKITHIISIHESPQPLLQDITYLRIPVADTPE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 VPIKKHFKECINFIHCCRLNGGNCLVHCFAGISRSTTIVTAYVMTVTGLGWRDVLEAIKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 VPIKKHFKECINFIHCCRLNGGNCLVHCFAGISRSTTIVTAYVMTVTGLGWRDVLEAIKA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 TRPIANPNPGFRQQLEEFGWASSQKLRRQLEERFGESPFRDEEELRALLPLCKRCRQGSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 TRPIANPNPGFRQQLEEFGWASSQKLRRQLEERFGESPFRDEEELRALLPLCKRCRQGSA
130 140 150 160 170 180
190 200 210 220 230
pF1KE5 TSASSAGPHSAASEGTLQRLVPRTPREAHRPLPLLARVKQTFSCLPRCLSRKGGK
::::::::::::::::.::::::::::::::::::::::::::::::::::::::
CCDS13 TSASSAGPHSAASEGTVQRLVPRTPREAHRPLPLLARVKQTFSCLPRCLSRKGGK
190 200 210 220 230
>>CCDS82607.1 DUSP15 gene_id:128853|Hs108|chr20 (232 aa)
initn: 1556 init1: 1556 opt: 1557 Z-score: 1688.7 bits: 319.8 E(32554): 9.7e-88
Smith-Waterman score: 1557; 98.7% identity (99.6% similar) in 232 aa overlap (5-235:1-232)
10 20 30 40 50
pF1KE5 MGNGMTK-VLPGLYLGNFIDAKDLDQLGRNKITHIISIHESPQPLLQDITYLRIPVADTP
::. ::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 MTEGVLPGLYLGNFIDAKDLDQLGRNKITHIISIHESPQPLLQDITYLRIPVADTP
10 20 30 40 50
60 70 80 90 100 110
pF1KE5 EVPIKKHFKECINFIHCCRLNGGNCLVHCFAGISRSTTIVTAYVMTVTGLGWRDVLEAIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 EVPIKKHFKECINFIHCCRLNGGNCLVHCFAGISRSTTIVTAYVMTVTGLGWRDVLEAIK
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE5 ATRPIANPNPGFRQQLEEFGWASSQKLRRQLEERFGESPFRDEEELRALLPLCKRCRQGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 ATRPIANPNPGFRQQLEEFGWASSQKLRRQLEERFGESPFRDEEELRALLPLCKRCRQGS
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE5 ATSASSAGPHSAASEGTLQRLVPRTPREAHRPLPLLARVKQTFSCLPRCLSRKGGK
:::::::::::::::::.::::::::::::::::::::::::::::::::::::::
CCDS82 ATSASSAGPHSAASEGTVQRLVPRTPREAHRPLPLLARVKQTFSCLPRCLSRKGGK
180 190 200 210 220 230
>>CCDS82606.1 DUSP15 gene_id:128853|Hs108|chr20 (295 aa)
initn: 952 init1: 952 opt: 953 Z-score: 1035.8 bits: 199.3 E(32554): 2.3e-51
Smith-Waterman score: 953; 96.6% identity (97.9% similar) in 146 aa overlap (5-149:1-146)
10 20 30 40 50
pF1KE5 MGNGMTK-VLPGLYLGNFIDAKDLDQLGRNKITHIISIHESPQPLLQDITYLRIPVADTP
::. ::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 MTEGVLPGLYLGNFIDAKDLDQLGRNKITHIISIHESPQPLLQDITYLRIPVADTP
10 20 30 40 50
60 70 80 90 100 110
pF1KE5 EVPIKKHFKECINFIHCCRLNGGNCLVHCFAGISRSTTIVTAYVMTVTGLGWRDVLEAIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 EVPIKKHFKECINFIHCCRLNGGNCLVHCFAGISRSTTIVTAYVMTVTGLGWRDVLEAIK
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE5 ATRPIANPNPGFRQQLEEFGWASSQKLRRQLEERFGESPFRDEEELRALLPLCKRCRQGS
:::::::::::::::::::::::::: :.
CCDS82 ATRPIANPNPGFRQQLEEFGWASSQKGARHRTSKTSGAQCPPMTSATCLLAARVALLSAA
120 130 140 150 160 170
>>CCDS42862.1 DUSP15 gene_id:128853|Hs108|chr20 (132 aa)
initn: 895 init1: 895 opt: 895 Z-score: 978.0 bits: 187.5 E(32554): 3.7e-48
Smith-Waterman score: 895; 99.2% identity (100.0% similar) in 132 aa overlap (104-235:1-132)
80 90 100 110 120 130
pF1KE5 IHCCRLNGGNCLVHCFAGISRSTTIVTAYVMTVTGLGWRDVLEAIKATRPIANPNPGFRQ
::::::::::::::::::::::::::::::
CCDS42 MTVTGLGWRDVLEAIKATRPIANPNPGFRQ
10 20 30
140 150 160 170 180 190
pF1KE5 QLEEFGWASSQKLRRQLEERFGESPFRDEEELRALLPLCKRCRQGSATSASSAGPHSAAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 QLEEFGWASSQKLRRQLEERFGESPFRDEEELRALLPLCKRCRQGSATSASSAGPHSAAS
40 50 60 70 80 90
200 210 220 230
pF1KE5 EGTLQRLVPRTPREAHRPLPLLARVKQTFSCLPRCLSRKGGK
:::.::::::::::::::::::::::::::::::::::::::
CCDS42 EGTVQRLVPRTPREAHRPLPLLARVKQTFSCLPRCLSRKGGK
100 110 120 130
>>CCDS69035.1 DUSP22 gene_id:56940|Hs108|chr6 (205 aa)
initn: 686 init1: 686 opt: 687 Z-score: 751.0 bits: 146.1 E(32554): 1.6e-35
Smith-Waterman score: 687; 53.9% identity (80.3% similar) in 178 aa overlap (1-178:1-176)
10 20 30 40 50 60
pF1KE5 MGNGMTKVLPGLYLGNFIDAKDLDQLGRNKITHIISIHESPQPLLQDITYLRIPVADTPE
:::::.:.:::::.::: ::.: .::..::.:::.:.:.: .:.:. . :: ::.::.:
CCDS69 MGNGMNKILPGLYIGNFKDARDAEQLSKNKVTHILSVHDSARPMLEGVKYLCIPAADSPS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 VPIKKHFKECINFIHCCRLNGGNCLVHCFAGISRSTTIVTAYVMTVTGLGWRDVLEAIKA
. .:::: :.::: ::: : .:::::.::.:::.:.: ::.:::: .::.:.:....:
CCDS69 QNLTRHFKESIKFIHECRLRGESCLVHCLAGVSRSVTLVIAYIMTVTDFGWEDALHTVRA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 TRPIANPNPGFRQQLEEFGWASSQKLRRQLEERFGESPFRDEEELRALLPLCKRCRQGSA
: :::: ::..::.:: .. :. :.:..::::..: :: . .: : .::
CCDS69 GRSCANPNVGFQRQLQEFEKHEVHQYRQWLKEEYGESPLQDAEEAKNILG--KYKEQGRT
130 140 150 160 170
190 200 210 220 230
pF1KE5 TSASSAGPHSAASEGTLQRLVPRTPREAHRPLPLLARVKQTFSCLPRCLSRKGGK
CCDS69 EPQPGARRWSSFPALAPLTYDNYTTET
180 190 200
>>CCDS4468.1 DUSP22 gene_id:56940|Hs108|chr6 (184 aa)
initn: 686 init1: 686 opt: 686 Z-score: 750.6 bits: 145.9 E(32554): 1.7e-35
Smith-Waterman score: 686; 55.0% identity (82.2% similar) in 169 aa overlap (1-169:1-169)
10 20 30 40 50 60
pF1KE5 MGNGMTKVLPGLYLGNFIDAKDLDQLGRNKITHIISIHESPQPLLQDITYLRIPVADTPE
:::::.:.:::::.::: ::.: .::..::.:::.:.:.: .:.:. . :: ::.::.:
CCDS44 MGNGMNKILPGLYIGNFKDARDAEQLSKNKVTHILSVHDSARPMLEGVKYLCIPAADSPS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 VPIKKHFKECINFIHCCRLNGGNCLVHCFAGISRSTTIVTAYVMTVTGLGWRDVLEAIKA
. .:::: :.::: ::: : .:::::.::.:::.:.: ::.:::: .::.:.:....:
CCDS44 QNLTRHFKESIKFIHECRLRGESCLVHCLAGVSRSVTLVIAYIMTVTDFGWEDALHTVRA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 TRPIANPNPGFRQQLEEFGWASSQKLRRQLEERFGESPFRDEEELRALLPLCKRCRQGSA
: :::: ::..::.:: .. :. :.:..::::..: :: . .:
CCDS44 GRSCANPNVGFQRQLQEFEKHEVHQYRQWLKEEYGESPLQDAEEAKNILAAPGILKFWAF
130 140 150 160 170 180
190 200 210 220 230
pF1KE5 TSASSAGPHSAASEGTLQRLVPRTPREAHRPLPLLARVKQTFSCLPRCLSRKGGK
CCDS44 LRRL
>>CCDS13883.1 DUSP18 gene_id:150290|Hs108|chr22 (188 aa)
initn: 234 init1: 234 opt: 310 Z-score: 344.9 bits: 70.8 E(32554): 6.9e-13
Smith-Waterman score: 310; 31.0% identity (62.6% similar) in 171 aa overlap (3-171:18-188)
10 20 30 40
pF1KE5 MGNGMTKVLPGLYLGNFIDAKDLDQLGRNKITHIISIH-ESPQPL
.:.... .::..: . :.. .:. :.:: .:.. : . :
CCDS13 MTAPSCAFPVQFRQPSVSGLSQITKSLYISNGVAANNKLMLSSNQITMVINVSVEVVNTL
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE5 LQDITYLRIPVADTPEVPIKKHFKECINFIHCCRLNGGNCLVHCFAGISRSTTIVTAYVM
.:: :...::::.:. . : . :: ... : :.:: ::.:::... ::.:
CCDS13 YEDIQYMQVPVADSPNSRLCDFFDPIADHIHSVEMKQGRTLLHCAAGVSRSAALCLAYLM
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE5 TVTGLGWRDVLEAIKATRPIANPNPGFRQQLEEFGWAS-SQKLRRQLEERFGESPFRDEE
... :. :. ::: :: :: .:: .. . ... ... : : :.
CCDS13 KYHAMSLLDAHTWTKSCRPIIRPNSGFWEQLIHYEFQLFGKNTVHMVSSPVGMIPDIYEK
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE5 ELRALLPLCKRCRQGSATSASSAGPHSAASEGTLQRLVPRTPREAHRPLPLLARVKQTFS
:.: ..::
CCDS13 EVRLMIPL
>>CCDS1528.1 DUSP10 gene_id:11221|Hs108|chr1 (482 aa)
initn: 279 init1: 201 opt: 311 Z-score: 340.3 bits: 71.3 E(32554): 1.2e-12
Smith-Waterman score: 311; 38.4% identity (67.4% similar) in 138 aa overlap (5-138:322-458)
10 20 30
pF1KE5 MGNGMTKVLPGLYLGNFIDAKDLDQLGRNKITHI
.: .:: :.::: ::.::: . : .: ..
CCDS15 ECREVGGGASAASSLLPQPIPTTPDIENAELTPILPFLFLGNEQDAQDLDTMQRLNIGYV
300 310 320 330 340 350
40 50 60 70 80 90
pF1KE5 ISIHESPQPLLQD----ITYLRIPVADTPEVPIKKHFKECINFIHCCRLNGGNCLVHCFA
:.. . :: . ..: :.:..:. . ....:.: ..::. . : . :.:: :
CCDS15 INV-TTHLPLYHYEKGLFNYKRLPATDSNKQNLRQYFEEAFEFIEEAHQCGKGLLIHCQA
360 370 380 390 400 410
100 110 120 130 140 150
pF1KE5 GISRSTTIVTAYVMTVTGLGWRDVLEAIKATRPIANPNPGFRQQLEEFGWASSQKLRRQL
:.:::.::: ::.: : . :. . .:. ::: .:: .: :: ::
CCDS15 GVSRSATIVIAYLMKHTRMTMTDAYKFVKGKRPIISPNLNFMGQLLEFEEDLNNGVTPRI
420 430 440 450 460 470
160 170 180 190 200 210
pF1KE5 EERFGESPFRDEEELRALLPLCKRCRQGSATSASSAGPHSAASEGTLQRLVPRTPREAHR
CCDS15 LTPKLMGVETVV
480
>>CCDS2289.1 DUSP19 gene_id:142679|Hs108|chr2 (217 aa)
initn: 302 init1: 217 opt: 306 Z-score: 339.7 bits: 70.1 E(32554): 1.3e-12
Smith-Waterman score: 306; 36.6% identity (65.5% similar) in 145 aa overlap (8-149:69-213)
10 20 30
pF1KE5 MGNGMTKVLPGLYLGNFIDAKDLDQLGRNKITHIISI
. : : ::. :.::: : .::.:::...
CCDS22 RIHVVEEVEPSSGGGCGYVQDLSSDLQVGVIKPWLLLGSQDAAHDLDTLKKNKVTHILNV
40 50 60 70 80 90
40 50 60 70 80 90
pF1KE5 -HESPQPLLQDITYLRIPVADTPEVPIKKHFKECINFIHCCRLNGGNCLVHCFAGISRST
. . .:.:.:: : . : ::. : ..: ::..::. . . : :::: ::.::..
CCDS22 AYGVENAFLSDFTYKSISILDLPETNILSYFPECFEFIEEAKRKDGVVLVHCNAGVSRAA
100 110 120 130 140 150
100 110 120 130 140 150
pF1KE5 TIVTAYVMTVTGLGWRDVLEAIKATRPIANPNPGFRQQLEEF--GWASSQKLRRQLEERF
.:: ...:. .. ... .: .:: :: :: .::. . : :.. : :
CCDS22 AIVIGFLMNSEQTSFTSAFSLVKNARPSICPNSGFMEQLRTYQEGKESNKCDRIQENSS
160 170 180 190 200 210
160 170 180 190 200 210
pF1KE5 GESPFRDEEELRALLPLCKRCRQGSATSASSAGPHSAASEGTLQRLVPRTPREAHRPLPL
>>CCDS7724.1 DUSP8 gene_id:1850|Hs108|chr11 (625 aa)
initn: 260 init1: 180 opt: 306 Z-score: 333.4 bits: 70.4 E(32554): 3e-12
Smith-Waterman score: 306; 32.7% identity (58.7% similar) in 196 aa overlap (4-197:160-352)
10 20 30
pF1KE5 MGNGMTKVLPGLYLGNFIDAKDLDQLGRNKITH
:.:..:: ::::. :. . : . .: :..
CCDS77 SSCFPGLCEGKPAALLPMSLSQPCLPVPSVGLTRILPHLYLGSQKDVLNKDLMTQNGISY
130 140 150 160 170 180
40 50 60 70 80 90
pF1KE5 IISIHES-PQP-LLQDITYLRIPVADTPEVPIKKHFKECINFIHCCRLNGGNCLVHCFAG
... .: :.: .. . ..:.:. :. . . . :.:: .:.. . .:::.::
CCDS77 VLNASNSCPKPDFICESRFMRVPINDNYCEKLLPWLDKSIEFIDKAKLSSCQVIVHCLAG
190 200 210 220 230 240
100 110 120 130 140 150
pF1KE5 ISRSTTIVTAYVMTVTGLGWRDVLEAIKATRPIANPNPGFRQQLEEFGWASSQKLRRQLE
::::.::. ::.: . :.. :. . .: :: .:: .: :: :. : :: :.
CCDS77 ISRSATIAIAYIMKTMGMSSDDAYRFVKDRRPSISPNFNFLGQLLEY--ERSLKLLAALQ
250 260 270 280 290 300
160 170 180 190 200 210
pF1KE5 ERFGESPFRDEEELRALLPLCKRCRQGSATSASSAGPHSAASEGTLQRLVPRTPREAHRP
: .: : . : :: :.: ..:: :: :
CCDS77 GDPG-TPSGTPEPPPSPAAGAPLPRLPPPTSESAATGNAAAREGGLSAGGEPPAPPTPPA
310 320 330 340 350 360
220 230
pF1KE5 LPLLARVKQTFSCLPRCLSRKGGK
CCDS77 TSALQQGLRGLHLSSDRLQDTNRLKRSFSLDIKSAYAPSRRPDGPGPPDPGEAPKLCKLD
370 380 390 400 410 420
235 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 23:21:29 2016 done: Mon Nov 7 23:21:30 2016
Total Scan time: 2.450 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]