Result of FASTA (omim) for
pFN21AE5275
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5275, 217 aa
1>>>pF1KE5275 217 - 217 aa - 217 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.9408+/-0.000348; mu= 16.0454+/- 0.022
mean_var=66.1962+/-13.124, 0's: 0 Z-trim(113.3): 24 B-trim: 0 in 0/54
Lambda= 0.157637
statistics sampled from 22561 (22585) to 22561 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.648), E-opt: 0.2 (0.265), width: 16
Scan time: 5.210
The best scores are: opt bits E(85289)
NP_002050 (OMIM: 139240) growth hormone variant is ( 217) 1431 334.0 1.1e-91
NP_000506 (OMIM: 139250,173100,262400,262650,61278 ( 217) 1321 309.0 3.8e-84
NP_066271 (OMIM: 118820) chorionic somatomammotrop ( 217) 1135 266.7 2.1e-71
NP_001308 (OMIM: 150200) chorionic somatomammotrop ( 217) 1129 265.3 5.4e-71
NP_072101 (OMIM: 603515) chorionic somatomammotrop ( 222) 1040 245.1 6.8e-65
NP_072051 (OMIM: 139240) growth hormone variant is ( 256) 998 235.6 5.7e-62
NP_072052 (OMIM: 139240) growth hormone variant is ( 245) 974 230.1 2.4e-60
NP_072050 (OMIM: 139240) growth hormone variant is ( 202) 972 229.6 2.8e-60
NP_072053 (OMIM: 139250,173100,262400,262650,61278 ( 202) 893 211.6 7.3e-55
NP_001307998 (OMIM: 603515) chorionic somatomammot ( 183) 795 189.3 3.4e-48
NP_001307996 (OMIM: 603515) chorionic somatomammot ( 162) 788 187.7 9.4e-48
NP_072054 (OMIM: 139250,173100,262400,262650,61278 ( 177) 748 178.6 5.5e-45
NP_072170 (OMIM: 118820) chorionic somatomammotrop ( 167) 740 176.8 1.9e-44
XP_011522646 (OMIM: 603515) PREDICTED: chorionic s ( 261) 677 162.6 5.4e-40
NP_072102 (OMIM: 603515) chorionic somatomammotrop ( 139) 669 160.6 1.2e-39
NP_001307997 (OMIM: 603515) chorionic somatomammot ( 160) 669 160.6 1.3e-39
NP_072103 (OMIM: 603515) chorionic somatomammotrop ( 199) 668 160.5 1.8e-39
NP_001309 (OMIM: 603515) chorionic somatomammotrop ( 128) 635 152.8 2.3e-37
XP_011522648 (OMIM: 603515) PREDICTED: chorionic s ( 201) 425 105.2 7.9e-23
NP_072171 (OMIM: 118820) chorionic somatomammotrop ( 122) 411 101.9 4.9e-22
XP_011513056 (OMIM: 176760) PREDICTED: prolactin i ( 228) 232 61.4 1.4e-09
XP_011513055 (OMIM: 176760) PREDICTED: prolactin i ( 228) 232 61.4 1.4e-09
NP_001157030 (OMIM: 176760) prolactin precursor [H ( 227) 227 60.2 3.1e-09
NP_000939 (OMIM: 176760) prolactin precursor [Homo ( 227) 227 60.2 3.1e-09
>>NP_002050 (OMIM: 139240) growth hormone variant isofor (217 aa)
initn: 1431 init1: 1431 opt: 1431 Z-score: 1766.8 bits: 334.0 E(85289): 1.1e-91
Smith-Waterman score: 1431; 100.0% identity (100.0% similar) in 217 aa overlap (1-217:1-217)
10 20 30 40 50 60
pF1KE5 MAAGSRTSLLLAFGLLCLSWLQEGSAFPTIPLSRLFDNAMLRARRLYQLAYDTYQEFEEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MAAGSRTSLLLAFGLLCLSWLQEGSAFPTIPLSRLFDNAMLRARRLYQLAYDTYQEFEEA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 YILKEQKYSFLQNPQTSLCFSESIPTPSNRVKTQQKSNLELLRISLLLIQSWLEPVQLLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 YILKEQKYSFLQNPQTSLCFSESIPTPSNRVKTQQKSNLELLRISLLLIQSWLEPVQLLR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 SVFANSLVYGASDSNVYRHLKDLEEGIQTLMWRLEDGSPRTGQIFNQSYSKFDTKSHNDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 SVFANSLVYGASDSNVYRHLKDLEEGIQTLMWRLEDGSPRTGQIFNQSYSKFDTKSHNDD
130 140 150 160 170 180
190 200 210
pF1KE5 ALLKNYGLLYCFRKDMDKVETFLRIVQCRSVEGSCGF
:::::::::::::::::::::::::::::::::::::
NP_002 ALLKNYGLLYCFRKDMDKVETFLRIVQCRSVEGSCGF
190 200 210
>>NP_000506 (OMIM: 139250,173100,262400,262650,612781) s (217 aa)
initn: 1321 init1: 1321 opt: 1321 Z-score: 1631.6 bits: 309.0 E(85289): 3.8e-84
Smith-Waterman score: 1321; 93.1% identity (97.2% similar) in 217 aa overlap (1-217:1-217)
10 20 30 40 50 60
pF1KE5 MAAGSRTSLLLAFGLLCLSWLQEGSAFPTIPLSRLFDNAMLRARRLYQLAYDTYQEFEEA
::.::::::::::::::: ::::::::::::::::::::::::.::.:::.:::::::::
NP_000 MATGSRTSLLLAFGLLCLPWLQEGSAFPTIPLSRLFDNAMLRAHRLHQLAFDTYQEFEEA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 YILKEQKYSFLQNPQTSLCFSESIPTPSNRVKTQQKSNLELLRISLLLIQSWLEPVQLLR
:: ::::::::::::::::::::::::::: .:::::::::::::::::::::::::.::
NP_000 YIPKEQKYSFLQNPQTSLCFSESIPTPSNREETQQKSNLELLRISLLLIQSWLEPVQFLR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 SVFANSLVYGASDSNVYRHLKDLEEGIQTLMWRLEDGSPRTGQIFNQSYSKFDTKSHNDD
::::::::::::::::: :::::::::::: :::::::::::::.:.::::::.:::::
NP_000 SVFANSLVYGASDSNVYDLLKDLEEGIQTLMGRLEDGSPRTGQIFKQTYSKFDTNSHNDD
130 140 150 160 170 180
190 200 210
pF1KE5 ALLKNYGLLYCFRKDMDKVETFLRIVQCRSVEGSCGF
:::::::::::::::::::::::::::::::::::::
NP_000 ALLKNYGLLYCFRKDMDKVETFLRIVQCRSVEGSCGF
190 200 210
>>NP_066271 (OMIM: 118820) chorionic somatomammotropin h (217 aa)
initn: 1135 init1: 1135 opt: 1135 Z-score: 1403.0 bits: 266.7 E(85289): 2.1e-71
Smith-Waterman score: 1135; 80.2% identity (93.1% similar) in 217 aa overlap (1-217:1-217)
10 20 30 40 50 60
pF1KE5 MAAGSRTSLLLAFGLLCLSWLQEGSAFPTIPLSRLFDNAMLRARRLYQLAYDTYQEFEEA
:::::::::::::.:::: ::::..: :.:::::::.:::.:.: .::: ::::::::.
NP_066 MAAGSRTSLLLAFALLCLPWLQEAGAVQTVPLSRLFDHAMLQAHRAHQLAIDTYQEFEET
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 YILKEQKYSFLQNPQTSLCFSESIPTPSNRVKTQQKSNLELLRISLLLIQSWLEPVQLLR
:: :.::::::.. :::.:::.::::::: .:::::::::::::::::.::::::..::
NP_066 YIPKDQKYSFLHDSQTSFCFSDSIPTPSNMEETQQKSNLELLRISLLLIESWLEPVRFLR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 SVFANSLVYGASDSNVYRHLKDLEEGIQTLMWRLEDGSPRTGQIFNQSYSKFDTKSHNDD
:.:::.::: .:::. :. :::::::::::: :::::: :::::..:.::::::.::: :
NP_066 SMFANNLVYDTSDSDDYHLLKDLEEGIQTLMGRLEDGSRRTGQILKQTYSKFDTNSHNHD
130 140 150 160 170 180
190 200 210
pF1KE5 ALLKNYGLLYCFRKDMDKVETFLRIVQCRSVEGSCGF
::::::::::::::::::::::::.::::::::::::
NP_066 ALLKNYGLLYCFRKDMDKVETFLRMVQCRSVEGSCGF
190 200 210
>>NP_001308 (OMIM: 150200) chorionic somatomammotropin h (217 aa)
initn: 1129 init1: 1129 opt: 1129 Z-score: 1395.6 bits: 265.3 E(85289): 5.4e-71
Smith-Waterman score: 1129; 79.7% identity (92.6% similar) in 217 aa overlap (1-217:1-217)
10 20 30 40 50 60
pF1KE5 MAAGSRTSLLLAFGLLCLSWLQEGSAFPTIPLSRLFDNAMLRARRLYQLAYDTYQEFEEA
:: ::::::::::.:::: ::::..: :.:::::::.:::.:.: .::: ::::::::.
NP_001 MAPGSRTSLLLAFALLCLPWLQEAGAVQTVPLSRLFDHAMLQAHRAHQLAIDTYQEFEET
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 YILKEQKYSFLQNPQTSLCFSESIPTPSNRVKTQQKSNLELLRISLLLIQSWLEPVQLLR
:: :.::::::.. :::.:::.::::::: .:::::::::::::::::.::::::..::
NP_001 YIPKDQKYSFLHDSQTSFCFSDSIPTPSNMEETQQKSNLELLRISLLLIESWLEPVRFLR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 SVFANSLVYGASDSNVYRHLKDLEEGIQTLMWRLEDGSPRTGQIFNQSYSKFDTKSHNDD
:.:::.::: .:::. :. :::::::::::: :::::: :::::..:.::::::.::: :
NP_001 SMFANNLVYDTSDSDDYHLLKDLEEGIQTLMGRLEDGSRRTGQILKQTYSKFDTNSHNHD
130 140 150 160 170 180
190 200 210
pF1KE5 ALLKNYGLLYCFRKDMDKVETFLRIVQCRSVEGSCGF
::::::::::::::::::::::::.::::::::::::
NP_001 ALLKNYGLLYCFRKDMDKVETFLRMVQCRSVEGSCGF
190 200 210
>>NP_072101 (OMIM: 603515) chorionic somatomammotropin h (222 aa)
initn: 1048 init1: 788 opt: 1040 Z-score: 1286.1 bits: 245.1 E(85289): 6.8e-65
Smith-Waterman score: 1040; 74.8% identity (87.8% similar) in 222 aa overlap (1-217:1-222)
10 20 30 40 50
pF1KE5 MAAGSRTSLLLAFGLLCLSWLQEGSAFPTIPLSRLFDNAMLRARRLYQLAYDTYQEF---
:::::::::::::.:::: ::::..: :.:::::: .:::.:.: .::: ::::::
NP_072 MAAGSRTSLLLAFALLCLPWLQEAGAVQTVPLSRLFKEAMLQAHRAHQLAIDTYQEFISS
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE5 --EEAYILKEQKYSFLQNPQTSLCFSESIPTPSNRVKTQQKSNLELLRISLLLIQSWLEP
:::: ::::::::.. :::.:::.:::: :: .::::::::::.::::::.: :::
NP_072 WGMEAYITKEQKYSFLHDSQTSFCFSDSIPTSSNMEETQQKSNLELLHISLLLIESRLEP
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE5 VQLLRSVFANSLVYGASDSNVYRHLKDLEEGIQTLMWRLEDGSPRTGQIFNQSYSKFDTK
:..:::.:.:.::: .:::. :. ::::::::: :: :::::: ::: ..:.::::::.
NP_072 VRFLRSTFTNNLVYDTSDSDDYHLLKDLEEGIQMLMGRLEDGSHLTGQTLKQTYSKFDTN
130 140 150 160 170 180
180 190 200 210
pF1KE5 SHNDDALLKNYGLLYCFRKDMDKVETFLRIVQCRSVEGSCGF
::: ::::::::::.::::::::::::::.::::::::::::
NP_072 SHNHDALLKNYGLLHCFRKDMDKVETFLRMVQCRSVEGSCGF
190 200 210 220
>>NP_072051 (OMIM: 139240) growth hormone variant isofor (256 aa)
initn: 983 init1: 983 opt: 998 Z-score: 1233.6 bits: 235.6 E(85289): 5.7e-62
Smith-Waterman score: 998; 95.7% identity (96.3% similar) in 163 aa overlap (1-162:1-163)
10 20 30 40 50 60
pF1KE5 MAAGSRTSLLLAFGLLCLSWLQEGSAFPTIPLSRLFDNAMLRARRLYQLAYDTYQEFEEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_072 MAAGSRTSLLLAFGLLCLSWLQEGSAFPTIPLSRLFDNAMLRARRLYQLAYDTYQEFEEA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 YILKEQKYSFLQNPQTSLCFSESIPTPSNRVKTQQKSNLELLRISLLLIQSWLEPVQLLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_072 YILKEQKYSFLQNPQTSLCFSESIPTPSNRVKTQQKSNLELLRISLLLIQSWLEPVQLLR
70 80 90 100 110 120
130 140 150 160 170
pF1KE5 SVFANSLVYGASDSNVYRHLKDLEEGIQTLMW-RLEDGSPRTGQIFNQSYSKFDTKSHND
:::::::::::::::::::::::::::::::: :. : : :
NP_072 SVFANSLVYGASDSNVYRHLKDLEEGIQTLMWVRVAPGIPNPGAPLASRDWGEKHCCPLF
130 140 150 160 170 180
180 190 200 210
pF1KE5 DALLKNYGLLYCFRKDMDKVETFLRIVQCRSVEGSCGF
NP_072 SSQALTQENSPYSSFPLVNPPGLSLQPGGEGGKWMNERGREQCPSAWPLLLFLHFAEAGR
190 200 210 220 230 240
>>NP_072052 (OMIM: 139240) growth hormone variant isofor (245 aa)
initn: 982 init1: 963 opt: 974 Z-score: 1204.4 bits: 230.1 E(85289): 2.4e-60
Smith-Waterman score: 974; 93.3% identity (97.0% similar) in 164 aa overlap (1-163:1-162)
10 20 30 40 50 60
pF1KE5 MAAGSRTSLLLAFGLLCLSWLQEGSAFPTIPLSRLFDNAMLRARRLYQLAYDTYQEFEEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_072 MAAGSRTSLLLAFGLLCLSWLQEGSAFPTIPLSRLFDNAMLRARRLYQLAYDTYQEFEEA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 YILKEQKYSFLQNPQTSLCFSESIPTPSNRVKTQQKSNLELLRISLLLIQSWLEPVQLLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_072 YILKEQKYSFLQNPQTSLCFSESIPTPSNRVKTQQKSNLELLRISLLLIQSWLEPVQLLR
70 80 90 100 110 120
130 140 150 160 170
pF1KE5 SVFANSLVYGASDSNVYRHLKDLEEGIQTLM-WRLEDGSPRTGQIFNQSYSKFDTKSHND
::::::::::::::::::::::::::::::. :.. ..: :.
NP_072 SVFANSLVYGASDSNVYRHLKDLEEGIQTLIGWKM--AAPGLGRSSISPTASLTQNRTTM
130 140 150 160 170
180 190 200 210
pF1KE5 DALLKNYGLLYCFRKDMDKVETFLRIVQCRSVEGSCGF
NP_072 THCSRTTGCSTASGRTWTRSRHSCASCSAALWRAAVASSCPGGIPVTPPQCLSWSWKVLL
180 190 200 210 220 230
>>NP_072050 (OMIM: 139240) growth hormone variant isofor (202 aa)
initn: 1324 init1: 965 opt: 972 Z-score: 1203.1 bits: 229.6 E(85289): 2.8e-60
Smith-Waterman score: 1298; 93.1% identity (93.1% similar) in 217 aa overlap (1-217:1-202)
10 20 30 40 50 60
pF1KE5 MAAGSRTSLLLAFGLLCLSWLQEGSAFPTIPLSRLFDNAMLRARRLYQLAYDTYQEFEEA
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_072 MAAGSRTSLLLAFGLLCLSWLQEGSAFPTIPLSRLFDNAMLRARRLYQLAYDTYQEF---
10 20 30 40 50
70 80 90 100 110 120
pF1KE5 YILKEQKYSFLQNPQTSLCFSESIPTPSNRVKTQQKSNLELLRISLLLIQSWLEPVQLLR
::::::::::::::::::::::::::::::::::::::::::::::::
NP_072 ------------NPQTSLCFSESIPTPSNRVKTQQKSNLELLRISLLLIQSWLEPVQLLR
60 70 80 90 100
130 140 150 160 170 180
pF1KE5 SVFANSLVYGASDSNVYRHLKDLEEGIQTLMWRLEDGSPRTGQIFNQSYSKFDTKSHNDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_072 SVFANSLVYGASDSNVYRHLKDLEEGIQTLMWRLEDGSPRTGQIFNQSYSKFDTKSHNDD
110 120 130 140 150 160
190 200 210
pF1KE5 ALLKNYGLLYCFRKDMDKVETFLRIVQCRSVEGSCGF
:::::::::::::::::::::::::::::::::::::
NP_072 ALLKNYGLLYCFRKDMDKVETFLRIVQCRSVEGSCGF
170 180 190 200
>>NP_072053 (OMIM: 139250,173100,262400,262650,612781) s (202 aa)
initn: 1223 init1: 892 opt: 893 Z-score: 1106.0 bits: 211.6 E(85289): 7.3e-55
Smith-Waterman score: 1197; 86.6% identity (90.8% similar) in 217 aa overlap (1-217:1-202)
10 20 30 40 50 60
pF1KE5 MAAGSRTSLLLAFGLLCLSWLQEGSAFPTIPLSRLFDNAMLRARRLYQLAYDTYQEFEEA
::.::::::::::::::: ::::::::::::::::::::::::.::.:::.::::::
NP_072 MATGSRTSLLLAFGLLCLPWLQEGSAFPTIPLSRLFDNAMLRAHRLHQLAFDTYQEF---
10 20 30 40 50
70 80 90 100 110 120
pF1KE5 YILKEQKYSFLQNPQTSLCFSESIPTPSNRVKTQQKSNLELLRISLLLIQSWLEPVQLLR
:::::::::::::::::: .:::::::::::::::::::::::::.::
NP_072 ------------NPQTSLCFSESIPTPSNREETQQKSNLELLRISLLLIQSWLEPVQFLR
60 70 80 90 100
130 140 150 160 170 180
pF1KE5 SVFANSLVYGASDSNVYRHLKDLEEGIQTLMWRLEDGSPRTGQIFNQSYSKFDTKSHNDD
::::::::::::::::: :::::::::::: :::::::::::::.:.::::::.:::::
NP_072 SVFANSLVYGASDSNVYDLLKDLEEGIQTLMGRLEDGSPRTGQIFKQTYSKFDTNSHNDD
110 120 130 140 150 160
190 200 210
pF1KE5 ALLKNYGLLYCFRKDMDKVETFLRIVQCRSVEGSCGF
:::::::::::::::::::::::::::::::::::::
NP_072 ALLKNYGLLYCFRKDMDKVETFLRIVQCRSVEGSCGF
170 180 190 200
>>NP_001307998 (OMIM: 603515) chorionic somatomammotropi (183 aa)
initn: 794 init1: 794 opt: 795 Z-score: 986.1 bits: 189.3 E(85289): 3.4e-48
Smith-Waterman score: 851; 66.8% identity (77.0% similar) in 217 aa overlap (1-217:1-183)
10 20 30 40 50 60
pF1KE5 MAAGSRTSLLLAFGLLCLSWLQEGSAFPTIPLSRLFDNAMLRARRLYQLAYDTYQEFEEA
:::::::::::::.:::: :::: :::
NP_001 MAAGSRTSLLLAFALLCLPWLQE----------------------------------EEA
10 20
70 80 90 100 110 120
pF1KE5 YILKEQKYSFLQNPQTSLCFSESIPTPSNRVKTQQKSNLELLRISLLLIQSWLEPVQLLR
:: ::::::::.. :::.:::.:::: :: .::::::::::.::::::.: ::::..::
NP_001 YITKEQKYSFLHDSQTSFCFSDSIPTSSNMEETQQKSNLELLHISLLLIESRLEPVRFLR
30 40 50 60 70 80
130 140 150 160 170 180
pF1KE5 SVFANSLVYGASDSNVYRHLKDLEEGIQTLMWRLEDGSPRTGQIFNQSYSKFDTKSHNDD
:.:.:.::: .:::. :. ::::::::: :: :::::: ::: ..:.::::::.::: :
NP_001 STFTNNLVYDTSDSDDYHLLKDLEEGIQMLMGRLEDGSHLTGQTLKQTYSKFDTNSHNHD
90 100 110 120 130 140
190 200 210
pF1KE5 ALLKNYGLLYCFRKDMDKVETFLRIVQCRSVEGSCGF
:::::::::.::::::::::::::.::::::::::::
NP_001 ALLKNYGLLHCFRKDMDKVETFLRMVQCRSVEGSCGF
150 160 170 180
217 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 07:26:39 2016 done: Tue Nov 8 07:26:40 2016
Total Scan time: 5.210 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]