Result of FASTA (ccds) for
pFN21AE5257
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5257, 208 aa
1>>>pF1KE5257 208 - 208 aa - 208 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.0727+/-0.000657; mu= 15.1688+/- 0.040
mean_var=61.2030+/-12.210, 0's: 0 Z-trim(110.9): 34 B-trim: 358 in 1/49
Lambda= 0.163941
statistics sampled from 11947 (11981) to 11947 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.744), E-opt: 0.2 (0.368), width: 16
Scan time: 1.820
The best scores are: opt bits E(32554)
CCDS3950.1 FGF10 gene_id:2255|Hs108|chr5 ( 208) 1434 346.8 5.5e-96
CCDS10131.1 FGF7 gene_id:2252|Hs108|chr15 ( 194) 599 149.3 1.5e-36
CCDS12037.1 FGF22 gene_id:27006|Hs108|chr19 ( 170) 571 142.7 1.3e-34
CCDS9298.1 FGF9 gene_id:2254|Hs108|chr13 ( 208) 422 107.5 6.2e-24
CCDS75996.1 FGF16 gene_id:8823|Hs108|chrX ( 207) 413 105.4 2.7e-23
CCDS5998.1 FGF20 gene_id:26281|Hs108|chr8 ( 211) 401 102.5 2e-22
CCDS34021.1 FGF5 gene_id:2250|Hs108|chr4 ( 268) 363 93.6 1.2e-19
CCDS8195.1 FGF3 gene_id:2248|Hs108|chr11 ( 239) 338 87.7 6.6e-18
CCDS14665.1 FGF13 gene_id:2258|Hs108|chrX ( 245) 330 85.8 2.5e-17
CCDS14664.1 FGF13 gene_id:2258|Hs108|chrX ( 192) 328 85.2 2.8e-17
CCDS74241.1 FGF22 gene_id:27006|Hs108|chr19 ( 165) 325 84.5 4.1e-17
CCDS55512.1 FGF13 gene_id:2258|Hs108|chrX ( 199) 323 84.1 6.6e-17
CCDS55511.1 FGF13 gene_id:2258|Hs108|chrX ( 226) 323 84.1 7.4e-17
CCDS55513.1 FGF13 gene_id:2258|Hs108|chrX ( 255) 323 84.1 8.2e-17
CCDS3301.1 FGF12 gene_id:2257|Hs108|chr3 ( 243) 320 83.4 1.3e-16
CCDS46983.1 FGF12 gene_id:2257|Hs108|chr3 ( 181) 317 82.6 1.6e-16
CCDS8527.1 FGF6 gene_id:2251|Hs108|chr12 ( 208) 310 81.0 5.8e-16
CCDS9501.1 FGF14 gene_id:2259|Hs108|chr13 ( 247) 290 76.3 1.8e-14
CCDS9500.1 FGF14 gene_id:2259|Hs108|chr13 ( 252) 287 75.6 3e-14
CCDS4275.1 FGF1 gene_id:2246|Hs108|chr5 ( 155) 270 71.5 3.2e-13
CCDS8194.1 FGF4 gene_id:2249|Hs108|chr11 ( 206) 270 71.5 4.1e-13
CCDS11105.1 FGF11 gene_id:2256|Hs108|chr17 ( 225) 270 71.6 4.4e-13
CCDS34059.1 FGF2 gene_id:2247|Hs108|chr4 ( 288) 261 69.5 2.3e-12
>>CCDS3950.1 FGF10 gene_id:2255|Hs108|chr5 (208 aa)
initn: 1434 init1: 1434 opt: 1434 Z-score: 1836.8 bits: 346.8 E(32554): 5.5e-96
Smith-Waterman score: 1434; 100.0% identity (100.0% similar) in 208 aa overlap (1-208:1-208)
10 20 30 40 50 60
pF1KE5 MWKWILTHCASAFPHLPGCCCCCFLLLFLVSSVPVTCQALGQDMVSPEATNSSSSSFSSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS39 MWKWILTHCASAFPHLPGCCCCCFLLLFLVSSVPVTCQALGQDMVSPEATNSSSSSFSSP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 SSAGRHVRSYNHLQGDVRWRKLFSFTKYFLKIEKNGKVSGTKKENCPYSILEITSVEIGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS39 SSAGRHVRSYNHLQGDVRWRKLFSFTKYFLKIEKNGKVSGTKKENCPYSILEITSVEIGV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 VAVKAINSNYYLAMNKKGKLYGSKEFNNDCKLKERIEENGYNTYASFNWQHNGRQMYVAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS39 VAVKAINSNYYLAMNKKGKLYGSKEFNNDCKLKERIEENGYNTYASFNWQHNGRQMYVAL
130 140 150 160 170 180
190 200
pF1KE5 NGKGAPRRGQKTRRKNTSAHFLPMVVHS
::::::::::::::::::::::::::::
CCDS39 NGKGAPRRGQKTRRKNTSAHFLPMVVHS
190 200
>>CCDS10131.1 FGF7 gene_id:2252|Hs108|chr15 (194 aa)
initn: 692 init1: 523 opt: 599 Z-score: 769.9 bits: 149.3 E(32554): 1.5e-36
Smith-Waterman score: 609; 47.3% identity (75.4% similar) in 207 aa overlap (1-206:1-193)
10 20 30 40 50 60
pF1KE5 MWKWILTHCASAFPHLPGCCCCCFLLLFLVSSVPVTCQALGQDMVSPEATNSSSSSFSSP
: ::::: .: : :: .. ::... ..:. :: .:: ... . :::
CCDS10 MHKWILTW---ILPTL--LYRSCFHIICLVGTISLACN----DM-TPEQM-ATNVNCSSP
10 20 30 40
70 80 90 100 110
pF1KE5 SSAGRHVRSYNHLQG-DVRWRKLFSFTKYFLKIEKNGKVSGTKKENCPYSILEITSVEIG
::.:::....: :.: :.:: :...:.:.: :::.::.. . :.:.:: .: .:
CCDS10 E---RHTRSYDYMEGGDIRVRRLFCRTQWYLRIDKRGKVKGTQEMKNNYNIMEIRTVAVG
50 60 70 80 90 100
120 130 140 150 160 170
pF1KE5 VVAVKAINSNYYLAMNKKGKLYGSKEFNNDCKLKERIEENGYNTYASFNWQHNGRQMYVA
.::.:...:..::::::.::::..:: :.::..:: : :: :::::: .: ::: .:.::
CCDS10 IVAIKGVESEFYLAMNKEGKLYAKKECNEDCNFKELILENHYNTYASAKWTHNGGEMFVA
110 120 130 140 150 160
180 190 200
pF1KE5 LNGKGAPRRGQKTRRKNTSAHFLPMVVHS
:: :: : ::.::.... .::::::..
CCDS10 LNQKGIPVRGKKTKKEQKTAHFLPMAIT
170 180 190
>>CCDS12037.1 FGF22 gene_id:27006|Hs108|chr19 (170 aa)
initn: 635 init1: 571 opt: 571 Z-score: 735.0 bits: 142.7 E(32554): 1.3e-34
Smith-Waterman score: 571; 54.5% identity (85.5% similar) in 145 aa overlap (62-206:25-169)
40 50 60 70 80 90
pF1KE5 SVPVTCQALGQDMVSPEATNSSSSSFSSPSSAGRHVRSYNHLQGDVRWRKLFSFTKYFLK
::.: ::: ::.::::::.::: :..::.
CCDS12 MRRRLWLGLAWLLLARAPDAAGTPSASRGPRSYPHLEGDVRWRRLFSSTHFFLR
10 20 30 40 50
100 110 120 130 140 150
pF1KE5 IEKNGKVSGTKKENCPYSILEITSVEIGVVAVKAINSNYYLAMNKKGKLYGSKEFNNDCK
.. .:.:.::. .. ::::: ::..:::..::..:..:.:::..:.::::. .. ::.
CCDS12 VDPGGRVQGTRWRHGQDSILEIRSVHVGVVVIKAVSSGFYVAMNRRGRLYGSRLYTVDCR
60 70 80 90 100 110
160 170 180 190 200
pF1KE5 LKERIEENGYNTYASFNWQHNGRQMYVALNGKGAPRRGQKTRRKNTSAHFLPMVVHS
..:::::::.::::: :.. :. :..::. .:.:: : .::: . ::::::..:
CCDS12 FRERIEENGHNTYASQRWRRRGQPMFLALDRRGGPRPGGRTRRYHLSAHFLPVLVS
120 130 140 150 160 170
>>CCDS9298.1 FGF9 gene_id:2254|Hs108|chr13 (208 aa)
initn: 419 init1: 311 opt: 422 Z-score: 543.2 bits: 107.5 E(32554): 6.2e-24
Smith-Waterman score: 422; 43.0% identity (79.6% similar) in 142 aa overlap (64-203:48-189)
40 50 60 70 80 90
pF1KE5 PVTCQALGQDMVSPEATNSSSSSFSSPSSAGRHVRSYNHLQGDVRWRKLFSFTKYFLKIE
: : . .::.: .: :.:. : . :.:
CCDS92 PFGNVPVLPVDSPVLLSDHLGQSEAGGLPRGPAVTDLDHLKGILRRRQLYCRTGFHLEIF
20 30 40 50 60 70
100 110 120 130 140 150
pF1KE5 KNGKVSGTKKENCPYSILEITSVEIGVVAVKAINSNYYLAMNKKGKLYGSKEFNNDCKLK
:: ..::.:.. ..:::. :. .:.:......:. ::.::.::.::::......: ..
CCDS92 PNGTIQGTRKDHSRFGILEFISIAVGLVSIRGVDSGLYLGMNEKGELYGSEKLTQECVFR
80 90 100 110 120 130
160 170 180 190 200
pF1KE5 ERIEENGYNTYASFNWQH--NGRQMYVALNGKGAPRRGQKTRRKNTSAHFLPMVVHS
:..::: ::::.: ..: .::..::::: :.::.: .:.:.. .::::
CCDS92 EQFEENWYNTYSSNLYKHVDTGRRYYVALNKDGTPREGTRTKRHQKFTHFLPRPVDPDKV
140 150 160 170 180 190
CCDS92 PELYKDILSQS
200
>>CCDS75996.1 FGF16 gene_id:8823|Hs108|chrX (207 aa)
initn: 405 init1: 298 opt: 413 Z-score: 531.7 bits: 105.4 E(32554): 2.7e-23
Smith-Waterman score: 413; 43.4% identity (78.7% similar) in 136 aa overlap (70-203:53-188)
40 50 60 70 80 90
pF1KE5 LGQDMVSPEATNSSSSSFSSPSSAGRHVRSYNHLQGDVRWRKLFSFTKYFLKIEKNGKVS
. ::.: .: :.:. : . :.: :: :
CCDS75 GNVPLADSPGFLNERLGQIEGKLQRGSPTDFAHLKGILRRRQLYCRTGFHLEIFPNGTVH
30 40 50 60 70 80
100 110 120 130 140 150
pF1KE5 GTKKENCPYSILEITSVEIGVVAVKAINSNYYLAMNKKGKLYGSKEFNNDCKLKERIEEN
::.... ..:::. :. .:........:. ::.::..:.:::::... .: ..:..:::
CCDS75 GTRHDHSRFGILEFISLAVGLISIRGVDSGLYLGMNERGELYGSKKLTRECVFREQFEEN
90 100 110 120 130 140
160 170 180 190 200
pF1KE5 GYNTYASFNWQHNG--RQMYVALNGKGAPRRGQKTRRKNTSAHFLPMVVHS
:::::: ..:. ::.::::: :.::.: .:.:.. .::::
CCDS75 WYNTYASTLYKHSDSERQYYVALNKDGSPREGYRTKRHQKFTHFLPRPVDPSKLPSMSRD
150 160 170 180 190 200
CCDS75 LFHYR
>>CCDS5998.1 FGF20 gene_id:26281|Hs108|chr8 (211 aa)
initn: 391 init1: 292 opt: 401 Z-score: 516.3 bits: 102.5 E(32554): 2e-22
Smith-Waterman score: 401; 37.4% identity (71.3% similar) in 174 aa overlap (38-203:19-192)
10 20 30 40 50 60
pF1KE5 HCASAFPHLPGCCCCCFLLLFLVSSVPVTCQALGQDMVSPEATNSSSSSFSSPSSAGRHV
: .:. .. : : . :.: : .
CCDS59 MAPLAEVGGFLGGLEGLGQQVGSHFLLPPAGERPPLLGERRSAAERSA
10 20 30 40
70 80 90 100 110 120
pF1KE5 RS------YNHLQGDVRWRKLFSFTKYFLKIEKNGKVSGTKKENCPYSILEITSVEIGVV
:. ::.: .: :.:. : . :.: .:.:.::.... ..:::. :: .:.:
CCDS59 RGGPGAAQLAHLHGILRRRQLYCRTGFHLQILPDGSVQGTRQDHSLFGILEFISVAVGLV
50 60 70 80 90 100
130 140 150 160 170
pF1KE5 AVKAINSNYYLAMNKKGKLYGSKEFNNDCKLKERIEENGYNTYASFNWQHN--GRQMYVA
......:. ::.:: ::.::::......: ..:..::: ::::.: ..:. ::...::
CCDS59 SIRGVDSGLYLGMNDKGELYGSEKLTSECIFREQFEENWYNTYSSNIYKHGDTGRRYFVA
110 120 130 140 150 160
180 190 200
pF1KE5 LNGKGAPRRGQKTRRKNTSAHFLPMVVHS
:: :.:: : ...:.. .::::
CCDS59 LNKDGTPRDGARSKRHQKFTHFLPRPVDPERVPELYKDLLMYT
170 180 190 200 210
>>CCDS34021.1 FGF5 gene_id:2250|Hs108|chr4 (268 aa)
initn: 356 init1: 226 opt: 363 Z-score: 466.2 bits: 93.6 E(32554): 1.2e-19
Smith-Waterman score: 363; 39.5% identity (70.3% similar) in 172 aa overlap (38-203:48-217)
10 20 30 40 50 60
pF1KE5 HCASAFPHLPGCCCCCFLLLFLVSSVPVTCQALGQDMVSPEATNSSSSSFSSPSSAGRHV
:. .. : : :..: ..:..: .: : .
CCDS34 AWAHGEKRLAPKGQPGPAATDRNPRGSSSRQSSSSAMSSSSASSSPAASLGSQGS-GLEQ
20 30 40 50 60 70
70 80 90 100 110 120
pF1KE5 RSYNHLQGDVRWRKLFSFTK--YFLKIEKNGKVSGTKKENCPYSILEITSVEIGVVAVKA
:.. . : .:. . . :.: .:::.:... : :.::: .: :.:....
CCDS34 SSFQWSPSGRRTGSLYCRVGIGFHLQIYPDGKVNGSHEANM-LSVLEIFAVSQGIVGIRG
80 90 100 110 120 130
130 140 150 160 170 180
pF1KE5 INSNYYLAMNKKGKLYGSKEFNNDCKLKERIEENGYNTYAS--FNWQHNGRQMYVALNGK
. :: .:::.:::::..: .:..:::..::..::.:::::: ...::. ::::: .
CCDS34 VFSNKFLAMSKKGKLHASAKFTDDCKFRERFQENSYNTYASAIHRTEKTGREWYVALNKR
140 150 160 170 180 190
190 200
pF1KE5 GAPRRGQKTRRK--NTSAHFLPMVVHS
: .:: . : : . :.::::
CCDS34 GKAKRGCSPRVKPQHISTHFLPRFKQSEQPELSFTVTVPEKKKPPSPIKPKIPLSAPRKN
200 210 220 230 240 250
>>CCDS8195.1 FGF3 gene_id:2248|Hs108|chr11 (239 aa)
initn: 448 init1: 252 opt: 338 Z-score: 434.9 bits: 87.7 E(32554): 6.6e-18
Smith-Waterman score: 422; 47.4% identity (71.2% similar) in 156 aa overlap (63-206:29-183)
40 50 60 70 80 90
pF1KE5 VPVTCQALGQDMVSPEATNSSSSSFSSPSSAGRHVRSYNHLQGDVRWRKLFSFTKYFLKI
:: . :.:: : : :::. ::: :..
CCDS81 MGLIWLLLLSLLEPGWPAAGPGARLRRDAGGRGGVYEHLGGAPRRRKLYCATKYHLQL
10 20 30 40 50
100 110 120 130 140 150
pF1KE5 EKNGKVSGTKKENCPYSILEITSVEIGVVAVKAINSNYYLAMNKKGKLYGSKEFNNDCKL
. .:.:.:. :: :::::::.::.:.::.... :. ::::::.:.::.:.... .:..
CCDS81 HPSGRVNGSL-ENSAYSILEITAVEVGIVAIRGLFSGRYLAMNKRGRLYASEHYSAECEF
60 70 80 90 100 110
160 170 180 190 200
pF1KE5 KERIEENGYNTYASFNWQHNG------------RQMYVALNGKGAPRRGQKTRRKNTSAH
:::.: ::::::: .. . : ::..:::: :::: :::: . :.
CCDS81 VERIHELGYNTYASRLYRTVSSTPGARRQPSAERLWYVSVNGKGRPRRGFKTRRTQKSSL
120 130 140 150 160 170
pF1KE5 FLPMVVHS
::: :.
CCDS81 FLPRVLDHRDHEMVRQLQSGLPRPPGKGVQPRRRRQKQSPDNLEPSHVQASRLGSQLEAS
180 190 200 210 220 230
>>CCDS14665.1 FGF13 gene_id:2258|Hs108|chrX (245 aa)
initn: 257 init1: 236 opt: 330 Z-score: 424.6 bits: 85.8 E(32554): 2.5e-17
Smith-Waterman score: 330; 37.2% identity (70.3% similar) in 145 aa overlap (61-203:54-196)
40 50 60 70 80 90
pF1KE5 SSVPVTCQALGQDMVSPEATNSSSSSFSSPSSAGRHVRSYNHLQGDVRWRKLFSFTKYFL
:. :. : .:.: : ::.: : :
CCDS14 ACKCVSSPSKGKTSCDKNKLNVFSRVKLFGSKKRRRRRPEPQLKGIV--TKLYSRQGYHL
30 40 50 60 70 80
100 110 120 130 140 150
pF1KE5 KIEKNGKVSGTKKENCPYSILEITSVEIGVVAVKAINSNYYLAMNKKGKLYGSKEFNNDC
... .: ..::: :. :..... : . :::....... :::::..: :: :. :. .:
CCDS14 QLQADGTIDGTKDEDSTYTLFNLIPVGLRVVAIQGVQTKLYLAMNSEGYLYTSELFTPEC
90 100 110 120 130 140
160 170 180 190 200
pF1KE5 KLKERIEENGYNTYAS--FNWQHNGRQMYVALNGKGAPRRGQKTRRKNTSAHFLPMVVHS
:.:: . :: : ::.: . :..:: :..:: .: .:....... .:::::
CCDS14 KFKESVFENYYVTYSSMIYRQQQSGRGWYLGLNKEGEIMKGNHVKKNKPAAHFLPKPLKV
150 160 170 180 190 200
CCDS14 AMYKEPSLHDLTEFSRSGSGTPTKSRSVSGVLNGGKSMSHNEST
210 220 230 240
>>CCDS14664.1 FGF13 gene_id:2258|Hs108|chrX (192 aa)
initn: 251 init1: 236 opt: 328 Z-score: 423.6 bits: 85.2 E(32554): 2.8e-17
Smith-Waterman score: 328; 37.6% identity (70.9% similar) in 141 aa overlap (65-203:5-143)
40 50 60 70 80 90
pF1KE5 VTCQALGQDMVSPEATNSSSSSFSSPSSAGRHVRSYNHLQGDVRWRKLFSFTKYFLKIEK
:. : .:.: : ::.: : :...
CCDS14 MALLRKSYSEPQLKGIVT--KLYSRQGYHLQLQA
10 20 30
100 110 120 130 140 150
pF1KE5 NGKVSGTKKENCPYSILEITSVEIGVVAVKAINSNYYLAMNKKGKLYGSKEFNNDCKLKE
.: ..::: :. :..... : . :::....... :::::..: :: :. :. .::.::
CCDS14 DGTIDGTKDEDSTYTLFNLIPVGLRVVAIQGVQTKLYLAMNSEGYLYTSELFTPECKFKE
40 50 60 70 80 90
160 170 180 190 200
pF1KE5 RIEENGYNTYAS--FNWQHNGRQMYVALNGKGAPRRGQKTRRKNTSAHFLPMVVHS
. :: : ::.: . :..:: :..:: .: .:....... .:::::
CCDS14 SVFENYYVTYSSMIYRQQQSGRGWYLGLNKEGEIMKGNHVKKNKPAAHFLPKPLKVAMYK
100 110 120 130 140 150
CCDS14 EPSLHDLTEFSRSGSGTPTKSRSVSGVLNGGKSMSHNEST
160 170 180 190
208 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 22:56:47 2016 done: Mon Nov 7 22:56:48 2016
Total Scan time: 1.820 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]