Result of FASTA (omim) for
pFN21AE5246
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5246, 243 aa
1>>>pF1KE5246 243 - 243 aa - 243 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.6152+/-0.000296; mu= 18.0781+/- 0.019
mean_var=57.6719+/-11.262, 0's: 0 Z-trim(117.1): 32 B-trim: 66 in 1/56
Lambda= 0.168885
statistics sampled from 28767 (28799) to 28767 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.721), E-opt: 0.2 (0.338), width: 16
Scan time: 5.740
The best scores are: opt bits E(85289)
NP_899062 (OMIM: 612314) glutathione S-transferase ( 243) 1718 426.3 2.4e-119
XP_011537572 (OMIM: 612314) PREDICTED: glutathione ( 243) 1718 426.3 2.4e-119
NP_001177943 (OMIM: 612314) glutathione S-transfer ( 215) 1527 379.7 2.3e-105
NP_004823 (OMIM: 605482) glutathione S-transferase ( 241) 1098 275.2 7.2e-74
XP_006717687 (OMIM: 612314) PREDICTED: glutathione ( 183) 1093 273.9 1.4e-73
XP_011537573 (OMIM: 612314) PREDICTED: glutathione ( 166) 1088 272.6 2.9e-73
XP_011537574 (OMIM: 612314) PREDICTED: glutathione ( 166) 1088 272.6 2.9e-73
NP_001177932 (OMIM: 605482) glutathione S-transfer ( 213) 941 236.9 2.1e-62
XP_011537575 (OMIM: 612314) PREDICTED: glutathione ( 149) 867 218.8 4.3e-57
NP_001177942 (OMIM: 612314) glutathione S-transfer ( 209) 862 217.6 1.3e-56
XP_016871160 (OMIM: 612314) PREDICTED: glutathione ( 132) 858 216.5 1.8e-56
XP_016871159 (OMIM: 612314) PREDICTED: glutathione ( 132) 858 216.5 1.8e-56
NP_001177944 (OMIM: 612314) glutathione S-transfer ( 181) 671 171.1 1.2e-42
NP_001177931 (OMIM: 605482) glutathione S-transfer ( 208) 669 170.6 1.9e-42
NP_665877 (OMIM: 603758) maleylacetoacetate isomer ( 216) 186 52.9 5.2e-07
NP_001299589 (OMIM: 603758) maleylacetoacetate iso ( 161) 137 40.9 0.0016
>>NP_899062 (OMIM: 612314) glutathione S-transferase ome (243 aa)
initn: 1718 init1: 1718 opt: 1718 Z-score: 2263.5 bits: 426.3 E(85289): 2.4e-119
Smith-Waterman score: 1718; 100.0% identity (100.0% similar) in 243 aa overlap (1-243:1-243)
10 20 30 40 50 60
pF1KE5 MSGDATRTLGKGSQPPGPVPEGLIRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_899 MSGDATRTLGKGSQPPGPVPEGLIRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 EWYYTKHPFGHIPVLETSQCQLIYESVIACEYLDDAYPGRKLFPYDPYERARQKMLLELF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_899 EWYYTKHPFGHIPVLETSQCQLIYESVIACEYLDDAYPGRKLFPYDPYERARQKMLLELF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 CKVPHLTKECLVALRCGRECTNLKAALRQEFSNLEEILEYQNTTFFGGTCISMIDYLLWP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_899 CKVPHLTKECLVALRCGRECTNLKAALRQEFSNLEEILEYQNTTFFGGTCISMIDYLLWP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 WFERLDVYGILDCVSHTPALRLWISAMKWDPTVCALLMDKSIFQGFLNLYFQNNPNAFDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_899 WFERLDVYGILDCVSHTPALRLWISAMKWDPTVCALLMDKSIFQGFLNLYFQNNPNAFDF
190 200 210 220 230 240
pF1KE5 GLC
:::
NP_899 GLC
>>XP_011537572 (OMIM: 612314) PREDICTED: glutathione S-t (243 aa)
initn: 1718 init1: 1718 opt: 1718 Z-score: 2263.5 bits: 426.3 E(85289): 2.4e-119
Smith-Waterman score: 1718; 100.0% identity (100.0% similar) in 243 aa overlap (1-243:1-243)
10 20 30 40 50 60
pF1KE5 MSGDATRTLGKGSQPPGPVPEGLIRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSGDATRTLGKGSQPPGPVPEGLIRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 EWYYTKHPFGHIPVLETSQCQLIYESVIACEYLDDAYPGRKLFPYDPYERARQKMLLELF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EWYYTKHPFGHIPVLETSQCQLIYESVIACEYLDDAYPGRKLFPYDPYERARQKMLLELF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 CKVPHLTKECLVALRCGRECTNLKAALRQEFSNLEEILEYQNTTFFGGTCISMIDYLLWP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CKVPHLTKECLVALRCGRECTNLKAALRQEFSNLEEILEYQNTTFFGGTCISMIDYLLWP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 WFERLDVYGILDCVSHTPALRLWISAMKWDPTVCALLMDKSIFQGFLNLYFQNNPNAFDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WFERLDVYGILDCVSHTPALRLWISAMKWDPTVCALLMDKSIFQGFLNLYFQNNPNAFDF
190 200 210 220 230 240
pF1KE5 GLC
:::
XP_011 GLC
>>NP_001177943 (OMIM: 612314) glutathione S-transferase (215 aa)
initn: 1527 init1: 1527 opt: 1527 Z-score: 2012.8 bits: 379.7 E(85289): 2.3e-105
Smith-Waterman score: 1527; 100.0% identity (100.0% similar) in 215 aa overlap (29-243:1-215)
10 20 30 40 50 60
pF1KE5 MSGDATRTLGKGSQPPGPVPEGLIRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKP
::::::::::::::::::::::::::::::::
NP_001 MRFCPYSHRTRLVLKAKDIRHEVVNINLRNKP
10 20 30
70 80 90 100 110 120
pF1KE5 EWYYTKHPFGHIPVLETSQCQLIYESVIACEYLDDAYPGRKLFPYDPYERARQKMLLELF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EWYYTKHPFGHIPVLETSQCQLIYESVIACEYLDDAYPGRKLFPYDPYERARQKMLLELF
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE5 CKVPHLTKECLVALRCGRECTNLKAALRQEFSNLEEILEYQNTTFFGGTCISMIDYLLWP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CKVPHLTKECLVALRCGRECTNLKAALRQEFSNLEEILEYQNTTFFGGTCISMIDYLLWP
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE5 WFERLDVYGILDCVSHTPALRLWISAMKWDPTVCALLMDKSIFQGFLNLYFQNNPNAFDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WFERLDVYGILDCVSHTPALRLWISAMKWDPTVCALLMDKSIFQGFLNLYFQNNPNAFDF
160 170 180 190 200 210
pF1KE5 GLC
:::
NP_001 GLC
>>NP_004823 (OMIM: 605482) glutathione S-transferase ome (241 aa)
initn: 1103 init1: 683 opt: 1098 Z-score: 1447.2 bits: 275.2 E(85289): 7.2e-74
Smith-Waterman score: 1098; 64.0% identity (87.2% similar) in 242 aa overlap (1-242:1-241)
10 20 30 40 50 60
pF1KE5 MSGDATRTLGKGSQPPGPVPEGLIRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKP
:::...:.::::: :::::::: ::::::::::...::::::::: :::::.::::.:::
NP_004 MSGESARSLGKGSAPPGPVPEGSIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 EWYYTKHPFGHIPVLETSQCQLIYESVIACEYLDDAYPGRKLFPYDPYERARQKMLLELF
::.. :.::: .::::.:: ::::::.:.:::::.::::.::.: ::::.: :::.::::
NP_004 EWFFKKNPFGLVPVLENSQGQLIYESAITCEYLDEAYPGKKLLPDDPYEKACQKMILELF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 CKVPHLTKECLVALRCGRECTNLKAALRQEFSNLEEILEYQNTTFFGGTCISMIDYLLWP
::: :. .. . .. ..:: .:.::..:::.: ..::::::. :::::::.::
NP_004 SKVPSLVGS-FIRSQNKEDYAGLKEEFRKEFTKLEEVLTNKKTTFFGGNSISMIDYLIWP
130 140 150 160 170
190 200 210 220 230 240
pF1KE5 WFERLDVYGILDCVSHTPALRLWISAMKWDPTVCALLMDKSIFQGFLNLYFQNNPNAFDF
:::::... . .::.::: :.::..::: :::: ::: ... .::::.::.::.:.: :.
NP_004 WFERLEAMKLNECVDHTPKLKLWMAAMKEDPTVSALLTSEKDWQGFLELYLQNSPEACDY
180 190 200 210 220 230
pF1KE5 GLC
::
NP_004 GL
240
>>XP_006717687 (OMIM: 612314) PREDICTED: glutathione S-t (183 aa)
initn: 1115 init1: 1093 opt: 1093 Z-score: 1442.3 bits: 273.9 E(85289): 1.4e-73
Smith-Waterman score: 1093; 98.7% identity (99.4% similar) in 159 aa overlap (1-159:1-159)
10 20 30 40 50 60
pF1KE5 MSGDATRTLGKGSQPPGPVPEGLIRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MSGDATRTLGKGSQPPGPVPEGLIRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 EWYYTKHPFGHIPVLETSQCQLIYESVIACEYLDDAYPGRKLFPYDPYERARQKMLLELF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EWYYTKHPFGHIPVLETSQCQLIYESVIACEYLDDAYPGRKLFPYDPYERARQKMLLELF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 CKVPHLTKECLVALRCGRECTNLKAALRQEFSNLEEILEYQNTTFFGGTCISMIDYLLWP
::::::::::::::::::::::::::::::::::::. :
XP_006 CKVPHLTKECLVALRCGRECTNLKAALRQEFSNLEELCEPHASPAALDISHEVGPHSLCS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 WFERLDVYGILDCVSHTPALRLWISAMKWDPTVCALLMDKSIFQGFLNLYFQNNPNAFDF
XP_006 SHG
>>XP_011537573 (OMIM: 612314) PREDICTED: glutathione S-t (166 aa)
initn: 1087 init1: 1087 opt: 1088 Z-score: 1436.3 bits: 272.6 E(85289): 2.9e-73
Smith-Waterman score: 1088; 94.0% identity (96.4% similar) in 168 aa overlap (1-168:1-166)
10 20 30 40 50 60
pF1KE5 MSGDATRTLGKGSQPPGPVPEGLIRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSGDATRTLGKGSQPPGPVPEGLIRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 EWYYTKHPFGHIPVLETSQCQLIYESVIACEYLDDAYPGRKLFPYDPYERARQKMLLELF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EWYYTKHPFGHIPVLETSQCQLIYESVIACEYLDDAYPGRKLFPYDPYERARQKMLLELF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 CKVPHLTKECLVALRCGRECTNLKAALRQEFSNLEEILEYQNTTFFGGTCISMIDYLLWP
:::::::::::::::::::::::::::::::::::: . .. :. :
XP_011 CKVPHLTKECLVALRCGRECTNLKAALRQEFSNLEE--DRKKRKFIPG
130 140 150 160
190 200 210 220 230 240
pF1KE5 WFERLDVYGILDCVSHTPALRLWISAMKWDPTVCALLMDKSIFQGFLNLYFQNNPNAFDF
>>XP_011537574 (OMIM: 612314) PREDICTED: glutathione S-t (166 aa)
initn: 1087 init1: 1087 opt: 1088 Z-score: 1436.3 bits: 272.6 E(85289): 2.9e-73
Smith-Waterman score: 1088; 94.0% identity (96.4% similar) in 168 aa overlap (1-168:1-166)
10 20 30 40 50 60
pF1KE5 MSGDATRTLGKGSQPPGPVPEGLIRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSGDATRTLGKGSQPPGPVPEGLIRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 EWYYTKHPFGHIPVLETSQCQLIYESVIACEYLDDAYPGRKLFPYDPYERARQKMLLELF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EWYYTKHPFGHIPVLETSQCQLIYESVIACEYLDDAYPGRKLFPYDPYERARQKMLLELF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 CKVPHLTKECLVALRCGRECTNLKAALRQEFSNLEEILEYQNTTFFGGTCISMIDYLLWP
:::::::::::::::::::::::::::::::::::: . .. :. :
XP_011 CKVPHLTKECLVALRCGRECTNLKAALRQEFSNLEE--DRKKRKFIPG
130 140 150 160
190 200 210 220 230 240
pF1KE5 WFERLDVYGILDCVSHTPALRLWISAMKWDPTVCALLMDKSIFQGFLNLYFQNNPNAFDF
>>NP_001177932 (OMIM: 605482) glutathione S-transferase (213 aa)
initn: 946 init1: 526 opt: 941 Z-score: 1241.2 bits: 236.9 E(85289): 2.1e-62
Smith-Waterman score: 941; 62.1% identity (86.4% similar) in 214 aa overlap (29-242:1-213)
10 20 30 40 50 60
pF1KE5 MSGDATRTLGKGSQPPGPVPEGLIRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKP
:::::...::::::::: :::::.::::.:::
NP_001 MRFCPFAERTRLVLKAKGIRHEVININLKNKP
10 20 30
70 80 90 100 110 120
pF1KE5 EWYYTKHPFGHIPVLETSQCQLIYESVIACEYLDDAYPGRKLFPYDPYERARQKMLLELF
::.. :.::: .::::.:: ::::::.:.:::::.::::.::.: ::::.: :::.::::
NP_001 EWFFKKNPFGLVPVLENSQGQLIYESAITCEYLDEAYPGKKLLPDDPYEKACQKMILELF
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE5 CKVPHLTKECLVALRCGRECTNLKAALRQEFSNLEEILEYQNTTFFGGTCISMIDYLLWP
::: :. .. . .. ..:: .:.::..:::.: ..::::::. :::::::.::
NP_001 SKVPSLVGS-FIRSQNKEDYAGLKEEFRKEFTKLEEVLTNKKTTFFGGNSISMIDYLIWP
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE5 WFERLDVYGILDCVSHTPALRLWISAMKWDPTVCALLMDKSIFQGFLNLYFQNNPNAFDF
:::::... . .::.::: :.::..::: :::: ::: ... .::::.::.::.:.: :.
NP_001 WFERLEAMKLNECVDHTPKLKLWMAAMKEDPTVSALLTSEKDWQGFLELYLQNSPEACDY
160 170 180 190 200 210
pF1KE5 GLC
::
NP_001 GL
>>XP_011537575 (OMIM: 612314) PREDICTED: glutathione S-t (149 aa)
initn: 881 init1: 859 opt: 867 Z-score: 1145.9 bits: 218.8 E(85289): 4.3e-57
Smith-Waterman score: 867; 94.0% identity (95.5% similar) in 133 aa overlap (1-131:1-133)
10 20 30 40 50 60
pF1KE5 MSGDATRTLGKGSQPPGPVPEGLIRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSGDATRTLGKGSQPPGPVPEGLIRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 EWYYTKHPFGHIPVLETSQCQLIYESVIACEYLDDAYPGRKLFPYDPYERARQKMLLELF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EWYYTKHPFGHIPVLETSQCQLIYESVIACEYLDDAYPGRKLFPYDPYERARQKMLLELF
70 80 90 100 110 120
130 140 150 160 170
pF1KE5 CKV--PHLTKECLVALRCGRECTNLKAALRQEFSNLEEILEYQNTTFFGGTCISMIDYLL
::. :: . :
XP_011 CKLCEPHASPAALDISHEVGPHSLCSSHG
130 140
>>NP_001177942 (OMIM: 612314) glutathione S-transferase (209 aa)
initn: 884 init1: 862 opt: 862 Z-score: 1137.3 bits: 217.6 E(85289): 1.3e-56
Smith-Waterman score: 1411; 86.0% identity (86.0% similar) in 243 aa overlap (1-243:1-209)
10 20 30 40 50 60
pF1KE5 MSGDATRTLGKGSQPPGPVPEGLIRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSGDATRTLGKGSQPPGPVPEGLIRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 EWYYTKHPFGHIPVLETSQCQLIYESVIACEYLDDAYPGRKLFPYDPYERARQKMLLELF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EWYYTKHPFGHIPVLETSQCQLIYESVIACEYLDDAYPGRKLFPYDPYERARQKMLLELF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 CKVPHLTKECLVALRCGRECTNLKAALRQEFSNLEEILEYQNTTFFGGTCISMIDYLLWP
:: ::::::::::::::::::::::::
NP_001 CK----------------------------------ILEYQNTTFFGGTCISMIDYLLWP
130 140
190 200 210 220 230 240
pF1KE5 WFERLDVYGILDCVSHTPALRLWISAMKWDPTVCALLMDKSIFQGFLNLYFQNNPNAFDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WFERLDVYGILDCVSHTPALRLWISAMKWDPTVCALLMDKSIFQGFLNLYFQNNPNAFDF
150 160 170 180 190 200
pF1KE5 GLC
:::
NP_001 GLC
243 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 22:50:37 2016 done: Mon Nov 7 22:50:38 2016
Total Scan time: 5.740 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]