FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE5245, 187 aa
  1>>>pF1KE5245 187 - 187 aa - 187 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 4.9567+/-0.000711; mu= 14.5345+/- 0.043
 mean_var=56.9494+/-11.498, 0's: 0 Z-trim(108.6): 12  B-trim: 239 in 1/49
 Lambda= 0.169953
 statistics sampled from 10337 (10343) to 10337 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.707), E-opt: 0.2 (0.318), width:  16
 Scan time:  1.410

The best scores are:                                      opt bits E(32554)
CCDS2926.1 DHFR2 gene_id:200895|Hs108|chr3         ( 187) 1249 313.9 3.6e-86
CCDS47240.1 DHFR gene_id:1719|Hs108|chr5           ( 187) 1130 284.7 2.2e-77
CCDS78028.1 DHFR gene_id:1719|Hs108|chr5           ( 135)  821 208.9 1.1e-54
CCDS78029.1 DHFR gene_id:1719|Hs108|chr5           ( 129)  759 193.7 3.9e-50


>>CCDS2926.1 DHFR2 gene_id:200895|Hs108|chr3              (187 aa)
 initn: 1249 init1: 1249 opt: 1249  Z-score: 1660.4  bits: 313.9 E(32554): 3.6e-86
Smith-Waterman score: 1249; 100.0% identity (100.0% similar) in 187 aa overlap (1-187:1-187)

               10        20        30        40        50        60
pF1KE5 MFLLLNCIVAVSQNMGIGKNGDLPRPPLRNEFRYFQRMTTTSSVEGKQNLVIMGRKTWFS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS29 MFLLLNCIVAVSQNMGIGKNGDLPRPPLRNEFRYFQRMTTTSSVEGKQNLVIMGRKTWFS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE5 IPEKNRPLKDRINLVLSRELKEPPQGAHFLARSLDDALKLTERPELANKVDMIWIVGGSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS29 IPEKNRPLKDRINLVLSRELKEPPQGAHFLARSLDDALKLTERPELANKVDMIWIVGGSS
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE5 VYKEAMNHLGHLKLFVTRIMQDFESDTFFSEIDLEKYKLLPEYPGVLSDVQEGKHIKYKF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS29 VYKEAMNHLGHLKLFVTRIMQDFESDTFFSEIDLEKYKLLPEYPGVLSDVQEGKHIKYKF
              130       140       150       160       170       180

              
pF1KE5 EVCEKDD
       :::::::
CCDS29 EVCEKDD
              

>>CCDS47240.1 DHFR gene_id:1719|Hs108|chr5                (187 aa)
 initn: 1130 init1: 1130 opt: 1130  Z-score: 1502.7  bits: 284.7 E(32554): 2.2e-77
Smith-Waterman score: 1130; 93.4% identity (96.2% similar) in 183 aa overlap (5-187:5-187)

               10        20        30        40        50        60
pF1KE5 MFLLLNCIVAVSQNMGIGKNGDLPRPPLRNEFRYFQRMTTTSSVEGKQNLVIMGRKTWFS
           :::::::::::::::::::: :::::::::::::::::::::::::::::.:::::
CCDS47 MVGSLNCIVAVSQNMGIGKNGDLPWPPLRNEFRYFQRMTTTSSVEGKQNLVIMGKKTWFS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE5 IPEKNRPLKDRINLVLSRELKEPPQGAHFLARSLDDALKLTERPELANKVDMIWIVGGSS
       ::::::::: ::::::::::::::::::::.:::::::::::.:::::::::.:::::::
CCDS47 IPEKNRPLKGRINLVLSRELKEPPQGAHFLSRSLDDALKLTEQPELANKVDMVWIVGGSS
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE5 VYKEAMNHLGHLKLFVTRIMQDFESDTFFSEIDLEKYKLLPEYPGVLSDVQEGKHIKYKF
       :::::::: :::::::::::::::::::: :::::::::::::::::::::: : :::::
CCDS47 VYKEAMNHPGHLKLFVTRIMQDFESDTFFPEIDLEKYKLLPEYPGVLSDVQEEKGIKYKF
              130       140       150       160       170       180

              
pF1KE5 EVCEKDD
       :: ::.:
CCDS47 EVYEKND
              

>>CCDS78028.1 DHFR gene_id:1719|Hs108|chr5                (135 aa)
 initn: 836 init1: 821 opt: 821  Z-score: 1095.4  bits: 208.9 E(32554): 1.1e-54
Smith-Waterman score: 821; 91.9% identity (95.6% similar) in 135 aa overlap (53-187:1-135)

             30        40        50        60        70        80  
pF1KE5 LPRPPLRNEFRYFQRMTTTSSVEGKQNLVIMGRKTWFSIPEKNRPLKDRINLVLSRELKE
                                     ::.:::::::::::::: ::::::::::::
CCDS78                               MGKKTWFSIPEKNRPLKGRINLVLSRELKE
                                             10        20        30

             90       100       110       120       130       140  
pF1KE5 PPQGAHFLARSLDDALKLTERPELANKVDMIWIVGGSSVYKEAMNHLGHLKLFVTRIMQD
       ::::::::.:::::::::::.:::::::::.::::::::::::::: :::::::::::::
CCDS78 PPQGAHFLSRSLDDALKLTEQPELANKVDMVWIVGGSSVYKEAMNHPGHLKLFVTRIMQD
               40        50        60        70        80        90

            150       160       170       180       
pF1KE5 FESDTFFSEIDLEKYKLLPEYPGVLSDVQEGKHIKYKFEVCEKDD
       ::::::: :::::::::::::::::::::: : ::::::: ::.:
CCDS78 FESDTFFPEIDLEKYKLLPEYPGVLSDVQEEKGIKYKFEVYEKND
              100       110       120       130     

>>CCDS78029.1 DHFR gene_id:1719|Hs108|chr5                (129 aa)
 initn: 759 init1: 759 opt: 759  Z-score: 1013.5  bits: 193.7 E(32554): 3.9e-50
Smith-Waterman score: 759; 95.0% identity (98.3% similar) in 119 aa overlap (5-123:5-123)

               10        20        30        40        50        60
pF1KE5 MFLLLNCIVAVSQNMGIGKNGDLPRPPLRNEFRYFQRMTTTSSVEGKQNLVIMGRKTWFS
           :::::::::::::::::::: :::::::::::::::::::::::::::::.:::::
CCDS78 MVGSLNCIVAVSQNMGIGKNGDLPWPPLRNEFRYFQRMTTTSSVEGKQNLVIMGKKTWFS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE5 IPEKNRPLKDRINLVLSRELKEPPQGAHFLARSLDDALKLTERPELANKVDMIWIVGGSS
       ::::::::: ::::::::::::::::::::.:::::::::::.:::::::::.:::::::
CCDS78 IPEKNRPLKGRINLVLSRELKEPPQGAHFLSRSLDDALKLTEQPELANKVDMVWIVGGSS
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE5 VYKEAMNHLGHLKLFVTRIMQDFESDTFFSEIDLEKYKLLPEYPGVLSDVQEGKHIKYKF
       :::                                                         
CCDS78 VYKIPRCSL                                                   
                                                                   




187 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Mon Nov  7 22:50:03 2016 done: Mon Nov  7 22:50:04 2016
 Total Scan time:  1.410 Total Display time: -0.030

Function used was FASTA [36.3.4 Apr, 2011]