Result of FASTA (omim) for
pFN21AE5232
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5232, 251 aa
1>>>pF1KE5232 251 - 251 aa - 251 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.0714+/-0.000301; mu= -1.8808+/- 0.019
mean_var=211.9296+/-42.909, 0's: 0 Z-trim(124.0): 18 B-trim: 416 in 1/57
Lambda= 0.088101
statistics sampled from 44834 (44852) to 44834 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.823), E-opt: 0.2 (0.526), width: 16
Scan time: 6.250
The best scores are: opt bits E(85289)
NP_004485 (OMIM: 600339) hepatoma-derived growth f ( 240) 719 102.9 5.3e-22
XP_011507755 (OMIM: 600339) PREDICTED: hepatoma-de ( 208) 598 87.5 2e-17
NP_001306116 (OMIM: 600339) hepatoma-derived growt ( 208) 598 87.5 2e-17
XP_011507756 (OMIM: 600339) PREDICTED: hepatoma-de ( 208) 598 87.5 2e-17
NP_001306117 (OMIM: 600339) hepatoma-derived growt ( 208) 598 87.5 2e-17
XP_011507757 (OMIM: 600339) PREDICTED: hepatoma-de ( 208) 598 87.5 2e-17
NP_001119523 (OMIM: 600339) hepatoma-derived growt ( 233) 598 87.6 2.2e-17
NP_001119522 (OMIM: 600339) hepatoma-derived growt ( 256) 598 87.6 2.4e-17
NP_001306115 (OMIM: 600339) hepatoma-derived growt ( 263) 559 82.6 7.5e-16
NP_001304829 (OMIM: 603620) PC4 and SFRS1-interact ( 324) 459 70.0 5.9e-12
NP_057157 (OMIM: 616643) hepatoma-derived growth f ( 203) 449 68.6 9.9e-12
XP_006720617 (OMIM: 616643) PREDICTED: hepatoma-de ( 212) 449 68.6 1e-11
NP_001304827 (OMIM: 603620) PC4 and SFRS1-interact ( 329) 451 69.0 1.2e-11
NP_066967 (OMIM: 603620) PC4 and SFRS1-interacting ( 333) 451 69.0 1.2e-11
NP_001121689 (OMIM: 603620) PC4 and SFRS1-interact ( 530) 451 69.1 1.8e-11
NP_150091 (OMIM: 603620) PC4 and SFRS1-interacting ( 530) 451 69.1 1.8e-11
>>NP_004485 (OMIM: 600339) hepatoma-derived growth facto (240 aa)
initn: 791 init1: 450 opt: 719 Z-score: 516.0 bits: 102.9 E(85289): 5.3e-22
Smith-Waterman score: 816; 57.4% identity (70.5% similar) in 251 aa overlap (9-251:10-240)
10 20 30 40 50
pF1KE5 MSAYGMPMYKSGDLVFAKLKGYAHWPARIEHMTQP------NRYQVFFFGTHETAFLSP
:: :::::::.::: ::::::..: . :.::::::::::::::.:
NP_004 MSRSNRQKEYKCGDLVFAKMKGYPHWPARIDEMPEAAVKSTANKYQVFFFGTHETAFLGP
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE5 KRLFPYKECKEKFGKPNKRRGFSAGLWEIENNPTVQASDCPLASEKGSGDGPWPEPEAAE
: ::::.: ::::::::::.::: :::::::::::.:: ...:. . : :::::::
NP_004 KDLFPYEESKEKFGKPNKRKGFSEGLWEIENNPTVKASGYQSSQKKSCVEEPEPEPEAAE
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE5 GDEDKPTHAGGGGDELGKPDDDKPTEE--EKGPLKRSAGDPPEDAPKRPKEAAPDQEEEA
:: :: .: :..:: :: :.:..: ::: ::: ::: ::.::::::: . ::
NP_004 GDGDKKGNAEGSSDEEGKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEGEEK
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE5 EAERAAEAERAAAAAAATAVDEESPFLVAVENGSAPSEPGLVCEPPQPEEEELREEEVAD
:: . :.:: :. . ::..:.::::: ::: :::: :::
NP_004 EAA-TLEVER--------------PLPMEVEKNSTPSEPGSGRGPPQEEEEEEDEEE---
190 200 210 220
240 250
pF1KE5 EEASQEWHAEAPGGGDRDSL
::..: ::::: :..::
NP_004 -EATKE-DAEAPGIRDHESL
230 240
>>XP_011507755 (OMIM: 600339) PREDICTED: hepatoma-derive (208 aa)
initn: 661 init1: 450 opt: 598 Z-score: 433.8 bits: 87.5 E(85289): 2e-17
Smith-Waterman score: 695; 57.3% identity (70.6% similar) in 218 aa overlap (36-251:11-208)
10 20 30 40 50 60
pF1KE5 MPMYKSGDLVFAKLKGYAHWPARIEHMTQPNRYQVFFFGTHETAFLSPKRLFPYKECKEK
:.::::::::::::::.:: ::::.: :::
XP_011 MPEAAVKSTANKYQVFFFGTHETAFLGPKDLFPYEESKEK
10 20 30 40
70 80 90 100 110 120
pF1KE5 FGKPNKRRGFSAGLWEIENNPTVQASDCPLASEKGSGDGPWPEPEAAEGDEDKPTHAGGG
:::::::.::: :::::::::::.:: ...:. . : ::::::::: :: .: :.
XP_011 FGKPNKRKGFSEGLWEIENNPTVKASGYQSSQKKSCVEEPEPEPEAAEGDGDKKGNAEGS
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE5 GDELGKPDDDKPTEE--EKGPLKRSAGDPPEDAPKRPKEAAPDQEEEAEAERAAEAERAA
.:: :: :.:..: ::: ::: ::: ::.::::::: . :: :: . :.::
XP_011 SDEEGKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEGEEKEAA-TLEVER--
110 120 130 140 150
190 200 210 220 230 240
pF1KE5 AAAAATAVDEESPFLVAVENGSAPSEPGLVCEPPQPEEEELREEEVADEEASQEWHAEAP
:. . ::..:.::::: ::: :::: ::: ::..: ::::
XP_011 ------------PLPMEVEKNSTPSEPGSGRGPPQEEEEEEDEEE----EATKE-DAEAP
160 170 180 190 200
250
pF1KE5 GGGDRDSL
: :..::
XP_011 GIRDHESL
>>NP_001306116 (OMIM: 600339) hepatoma-derived growth fa (208 aa)
initn: 661 init1: 450 opt: 598 Z-score: 433.8 bits: 87.5 E(85289): 2e-17
Smith-Waterman score: 695; 57.3% identity (70.6% similar) in 218 aa overlap (36-251:11-208)
10 20 30 40 50 60
pF1KE5 MPMYKSGDLVFAKLKGYAHWPARIEHMTQPNRYQVFFFGTHETAFLSPKRLFPYKECKEK
:.::::::::::::::.:: ::::.: :::
NP_001 MPEAAVKSTANKYQVFFFGTHETAFLGPKDLFPYEESKEK
10 20 30 40
70 80 90 100 110 120
pF1KE5 FGKPNKRRGFSAGLWEIENNPTVQASDCPLASEKGSGDGPWPEPEAAEGDEDKPTHAGGG
:::::::.::: :::::::::::.:: ...:. . : ::::::::: :: .: :.
NP_001 FGKPNKRKGFSEGLWEIENNPTVKASGYQSSQKKSCVEEPEPEPEAAEGDGDKKGNAEGS
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE5 GDELGKPDDDKPTEE--EKGPLKRSAGDPPEDAPKRPKEAAPDQEEEAEAERAAEAERAA
.:: :: :.:..: ::: ::: ::: ::.::::::: . :: :: . :.::
NP_001 SDEEGKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEGEEKEAA-TLEVER--
110 120 130 140 150
190 200 210 220 230 240
pF1KE5 AAAAATAVDEESPFLVAVENGSAPSEPGLVCEPPQPEEEELREEEVADEEASQEWHAEAP
:. . ::..:.::::: ::: :::: ::: ::..: ::::
NP_001 ------------PLPMEVEKNSTPSEPGSGRGPPQEEEEEEDEEE----EATKE-DAEAP
160 170 180 190 200
250
pF1KE5 GGGDRDSL
: :..::
NP_001 GIRDHESL
>>XP_011507756 (OMIM: 600339) PREDICTED: hepatoma-derive (208 aa)
initn: 661 init1: 450 opt: 598 Z-score: 433.8 bits: 87.5 E(85289): 2e-17
Smith-Waterman score: 695; 57.3% identity (70.6% similar) in 218 aa overlap (36-251:11-208)
10 20 30 40 50 60
pF1KE5 MPMYKSGDLVFAKLKGYAHWPARIEHMTQPNRYQVFFFGTHETAFLSPKRLFPYKECKEK
:.::::::::::::::.:: ::::.: :::
XP_011 MPEAAVKSTANKYQVFFFGTHETAFLGPKDLFPYEESKEK
10 20 30 40
70 80 90 100 110 120
pF1KE5 FGKPNKRRGFSAGLWEIENNPTVQASDCPLASEKGSGDGPWPEPEAAEGDEDKPTHAGGG
:::::::.::: :::::::::::.:: ...:. . : ::::::::: :: .: :.
XP_011 FGKPNKRKGFSEGLWEIENNPTVKASGYQSSQKKSCVEEPEPEPEAAEGDGDKKGNAEGS
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE5 GDELGKPDDDKPTEE--EKGPLKRSAGDPPEDAPKRPKEAAPDQEEEAEAERAAEAERAA
.:: :: :.:..: ::: ::: ::: ::.::::::: . :: :: . :.::
XP_011 SDEEGKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEGEEKEAA-TLEVER--
110 120 130 140 150
190 200 210 220 230 240
pF1KE5 AAAAATAVDEESPFLVAVENGSAPSEPGLVCEPPQPEEEELREEEVADEEASQEWHAEAP
:. . ::..:.::::: ::: :::: ::: ::..: ::::
XP_011 ------------PLPMEVEKNSTPSEPGSGRGPPQEEEEEEDEEE----EATKE-DAEAP
160 170 180 190 200
250
pF1KE5 GGGDRDSL
: :..::
XP_011 GIRDHESL
>>NP_001306117 (OMIM: 600339) hepatoma-derived growth fa (208 aa)
initn: 661 init1: 450 opt: 598 Z-score: 433.8 bits: 87.5 E(85289): 2e-17
Smith-Waterman score: 695; 57.3% identity (70.6% similar) in 218 aa overlap (36-251:11-208)
10 20 30 40 50 60
pF1KE5 MPMYKSGDLVFAKLKGYAHWPARIEHMTQPNRYQVFFFGTHETAFLSPKRLFPYKECKEK
:.::::::::::::::.:: ::::.: :::
NP_001 MPEAAVKSTANKYQVFFFGTHETAFLGPKDLFPYEESKEK
10 20 30 40
70 80 90 100 110 120
pF1KE5 FGKPNKRRGFSAGLWEIENNPTVQASDCPLASEKGSGDGPWPEPEAAEGDEDKPTHAGGG
:::::::.::: :::::::::::.:: ...:. . : ::::::::: :: .: :.
NP_001 FGKPNKRKGFSEGLWEIENNPTVKASGYQSSQKKSCVEEPEPEPEAAEGDGDKKGNAEGS
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE5 GDELGKPDDDKPTEE--EKGPLKRSAGDPPEDAPKRPKEAAPDQEEEAEAERAAEAERAA
.:: :: :.:..: ::: ::: ::: ::.::::::: . :: :: . :.::
NP_001 SDEEGKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEGEEKEAA-TLEVER--
110 120 130 140 150
190 200 210 220 230 240
pF1KE5 AAAAATAVDEESPFLVAVENGSAPSEPGLVCEPPQPEEEELREEEVADEEASQEWHAEAP
:. . ::..:.::::: ::: :::: ::: ::..: ::::
NP_001 ------------PLPMEVEKNSTPSEPGSGRGPPQEEEEEEDEEE----EATKE-DAEAP
160 170 180 190 200
250
pF1KE5 GGGDRDSL
: :..::
NP_001 GIRDHESL
>>XP_011507757 (OMIM: 600339) PREDICTED: hepatoma-derive (208 aa)
initn: 661 init1: 450 opt: 598 Z-score: 433.8 bits: 87.5 E(85289): 2e-17
Smith-Waterman score: 695; 57.3% identity (70.6% similar) in 218 aa overlap (36-251:11-208)
10 20 30 40 50 60
pF1KE5 MPMYKSGDLVFAKLKGYAHWPARIEHMTQPNRYQVFFFGTHETAFLSPKRLFPYKECKEK
:.::::::::::::::.:: ::::.: :::
XP_011 MPEAAVKSTANKYQVFFFGTHETAFLGPKDLFPYEESKEK
10 20 30 40
70 80 90 100 110 120
pF1KE5 FGKPNKRRGFSAGLWEIENNPTVQASDCPLASEKGSGDGPWPEPEAAEGDEDKPTHAGGG
:::::::.::: :::::::::::.:: ...:. . : ::::::::: :: .: :.
XP_011 FGKPNKRKGFSEGLWEIENNPTVKASGYQSSQKKSCVEEPEPEPEAAEGDGDKKGNAEGS
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE5 GDELGKPDDDKPTEE--EKGPLKRSAGDPPEDAPKRPKEAAPDQEEEAEAERAAEAERAA
.:: :: :.:..: ::: ::: ::: ::.::::::: . :: :: . :.::
XP_011 SDEEGKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEGEEKEAA-TLEVER--
110 120 130 140 150
190 200 210 220 230 240
pF1KE5 AAAAATAVDEESPFLVAVENGSAPSEPGLVCEPPQPEEEELREEEVADEEASQEWHAEAP
:. . ::..:.::::: ::: :::: ::: ::..: ::::
XP_011 ------------PLPMEVEKNSTPSEPGSGRGPPQEEEEEEDEEE----EATKE-DAEAP
160 170 180 190 200
250
pF1KE5 GGGDRDSL
: :..::
XP_011 GIRDHESL
>>NP_001119523 (OMIM: 600339) hepatoma-derived growth fa (233 aa)
initn: 661 init1: 450 opt: 598 Z-score: 433.1 bits: 87.6 E(85289): 2.2e-17
Smith-Waterman score: 695; 57.3% identity (70.6% similar) in 218 aa overlap (36-251:36-233)
10 20 30 40 50 60
pF1KE5 MPMYKSGDLVFAKLKGYAHWPARIEHMTQPNRYQVFFFGTHETAFLSPKRLFPYKECKEK
:.::::::::::::::.:: ::::.: :::
NP_001 GGNRVQTSTLNCAGAAVIDEMPEAAVKSTANKYQVFFFGTHETAFLGPKDLFPYEESKEK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 FGKPNKRRGFSAGLWEIENNPTVQASDCPLASEKGSGDGPWPEPEAAEGDEDKPTHAGGG
:::::::.::: :::::::::::.:: ...:. . : ::::::::: :: .: :.
NP_001 FGKPNKRKGFSEGLWEIENNPTVKASGYQSSQKKSCVEEPEPEPEAAEGDGDKKGNAEGS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 GDELGKPDDDKPTEE--EKGPLKRSAGDPPEDAPKRPKEAAPDQEEEAEAERAAEAERAA
.:: :: :.:..: ::: ::: ::: ::.::::::: . :: :: . :.::
NP_001 SDEEGKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEGEEKEAA-TLEVER--
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 AAAAATAVDEESPFLVAVENGSAPSEPGLVCEPPQPEEEELREEEVADEEASQEWHAEAP
:. . ::..:.::::: ::: :::: ::: ::..: ::::
NP_001 ------------PLPMEVEKNSTPSEPGSGRGPPQEEEEEEDEEE----EATKE-DAEAP
190 200 210 220
250
pF1KE5 GGGDRDSL
: :..::
NP_001 GIRDHESL
230
>>NP_001119522 (OMIM: 600339) hepatoma-derived growth fa (256 aa)
initn: 661 init1: 450 opt: 598 Z-score: 432.5 bits: 87.6 E(85289): 2.4e-17
Smith-Waterman score: 695; 57.3% identity (70.6% similar) in 218 aa overlap (36-251:59-256)
10 20 30 40 50 60
pF1KE5 MPMYKSGDLVFAKLKGYAHWPARIEHMTQPNRYQVFFFGTHETAFLSPKRLFPYKECKEK
:.::::::::::::::.:: ::::.: :::
NP_001 GGRRAQIPDVSRATPHTIDEMPEAAVKSTANKYQVFFFGTHETAFLGPKDLFPYEESKEK
30 40 50 60 70 80
70 80 90 100 110 120
pF1KE5 FGKPNKRRGFSAGLWEIENNPTVQASDCPLASEKGSGDGPWPEPEAAEGDEDKPTHAGGG
:::::::.::: :::::::::::.:: ...:. . : ::::::::: :: .: :.
NP_001 FGKPNKRKGFSEGLWEIENNPTVKASGYQSSQKKSCVEEPEPEPEAAEGDGDKKGNAEGS
90 100 110 120 130 140
130 140 150 160 170 180
pF1KE5 GDELGKPDDDKPTEE--EKGPLKRSAGDPPEDAPKRPKEAAPDQEEEAEAERAAEAERAA
.:: :: :.:..: ::: ::: ::: ::.::::::: . :: :: . :.::
NP_001 SDEEGKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEGEEKEAA-TLEVER--
150 160 170 180 190 200
190 200 210 220 230 240
pF1KE5 AAAAATAVDEESPFLVAVENGSAPSEPGLVCEPPQPEEEELREEEVADEEASQEWHAEAP
:. . ::..:.::::: ::: :::: ::: ::..: ::::
NP_001 ------------PLPMEVEKNSTPSEPGSGRGPPQEEEEEEDEEE----EATKE-DAEAP
210 220 230 240
250
pF1KE5 GGGDRDSL
: :..::
NP_001 GIRDHESL
250
>>NP_001306115 (OMIM: 600339) hepatoma-derived growth fa (263 aa)
initn: 663 init1: 341 opt: 559 Z-score: 405.6 bits: 82.6 E(85289): 7.5e-16
Smith-Waterman score: 678; 56.4% identity (68.9% similar) in 225 aa overlap (36-251:59-263)
10 20 30 40 50 60
pF1KE5 MPMYKSGDLVFAKLKGYAHWPARIEHMTQPNRYQVFFFGTHETAFLSPKRLFPYKECKEK
:.::::::::::::::.:: ::::.: :::
NP_001 GGRRAQIPDVSRATPHTIDEMPEAAVKSTANKYQVFFFGTHETAFLGPKDLFPYEESKEK
30 40 50 60 70 80
70 80 90 100 110
pF1KE5 FGKPNKRRGFSAGLWEIENNPTVQASDC-PLAS------EKGSGDGPWPEPEAAEGDEDK
:::::::.::: :::::::::::.:: :. : .:. . : ::::::::: ::
NP_001 FGKPNKRKGFSEGLWEIENNPTVKASGYQPVLSLLQSSQKKSCVEEPEPEPEAAEGDGDK
90 100 110 120 130 140
120 130 140 150 160 170
pF1KE5 PTHAGGGGDELGKPDDDKPTEE--EKGPLKRSAGDPPEDAPKRPKEAAPDQEEEAEAERA
.: :..:: :: :.:..: ::: ::: ::: ::.::::::: . :: :: .
NP_001 KGNAEGSSDEEGKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEGEEKEAA-T
150 160 170 180 190 200
180 190 200 210 220 230
pF1KE5 AEAERAAAAAAATAVDEESPFLVAVENGSAPSEPGLVCEPPQPEEEELREEEVADEEASQ
:.:: :. . ::..:.::::: ::: :::: ::: ::..
NP_001 LEVER--------------PLPMEVEKNSTPSEPGSGRGPPQEEEEEEDEEE----EATK
210 220 230 240
240 250
pF1KE5 EWHAEAPGGGDRDSL
: ::::: :..::
NP_001 E-DAEAPGIRDHESL
250 260
>>NP_001304829 (OMIM: 603620) PC4 and SFRS1-interacting (324 aa)
initn: 457 init1: 280 opt: 459 Z-score: 335.6 bits: 70.0 E(85289): 5.9e-12
Smith-Waterman score: 459; 36.8% identity (62.0% similar) in 234 aa overlap (9-233:5-232)
10 20 30 40 50
pF1KE5 MSAYGMPMYKSGDLVFAKLKGYAHWPARIEHM----TQP--NRYQVFFFGTHETAFLSPK
.: :::.:::.::: :::::.... ..: :. .:::::::::::.::
NP_001 MTRDFKPGDLIFAKMKGYPHWPARVDEVPDGAVKPPTNKLPIFFFGTHETAFLGPK
10 20 30 40 50
60 70 80 90 100 110
pF1KE5 RLFPYKECKEKFGKPNKRRGFSAGLWEIENNPTVQASDCPLASEKG--SGDGPWPEPEAA
.:::.: :::.::::::.::. :::::.::: :. :. :.... :.: : :..
NP_001 DIFPYSENKEKYGKPNKRKGFNEGLWEIDNNPKVKFSSQQAATKQSNASSDVEVEEKETS
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE5 EGDEDKPTHAGGGGDELGKPDD-DKPTEEEKGPLKRSAGDPPEDAPKRPKEAAPDQEEEA
. :: . ...... : : : ..: ::.:: . . ...: . . :
NP_001 VSKEDTDHEEKASNEDVTKAVDITTPKAARRGR-KRKAGVVTTATASVNLKVSPKRGRPA
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE5 EAERAAEAERAAAAAAATAVDEESPFLVAVENGSAPSEPGLVCEPPQPEEEELREEEVAD
.: :. . :: ... :. : .. : : ::... ..::
NP_001 ATEVKIPKPRGRPKMVKQPCPSESD-IITEEDKS--KKKGQ--EEKQPKKQPKKDEEGQK
180 190 200 210 220 230
240 250
pF1KE5 EEASQEWHAEAPGGGDRDSL
::
NP_001 EEDKPRKEPDKKEGKKEVESKRKNLAKTGVTSTSDSEEEGDDQEGEKKRKGGRNFQTAHR
240 250 260 270 280 290
251 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 22:43:57 2016 done: Mon Nov 7 22:43:58 2016
Total Scan time: 6.250 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]