Result of FASTA (ccds) for
pFN21AE5223
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5223, 249 aa
1>>>pF1KE5223 249 - 249 aa - 249 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.1579+/-0.000865; mu= 11.5703+/- 0.052
mean_var=133.4681+/-27.626, 0's: 0 Z-trim(111.0): 142 B-trim: 235 in 1/51
Lambda= 0.111016
statistics sampled from 11886 (12070) to 11886 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.74), E-opt: 0.2 (0.371), width: 16
Scan time: 2.150
The best scores are: opt bits E(32554)
CCDS34665.1 TRIM73 gene_id:375593|Hs108|chr7 ( 250) 1714 285.4 2.5e-77
CCDS5545.1 TRIM74 gene_id:378108|Hs108|chr7 ( 250) 1704 283.8 7.4e-77
CCDS34654.1 TRIM50 gene_id:135892|Hs108|chr7 ( 487) 1566 262.0 5.3e-70
CCDS32437.1 TRIM72 gene_id:493829|Hs108|chr16 ( 477) 372 70.8 1.9e-12
CCDS4654.1 TRIM27 gene_id:5987|Hs108|chr6 ( 513) 354 67.9 1.5e-11
CCDS31392.1 TRIM5 gene_id:85363|Hs108|chr11 ( 326) 342 65.8 4.1e-11
CCDS31394.1 TRIM5 gene_id:85363|Hs108|chr11 ( 347) 342 65.8 4.3e-11
CCDS31393.1 TRIM5 gene_id:85363|Hs108|chr11 ( 493) 342 66.0 5.5e-11
CCDS34378.1 TRIM39 gene_id:56658|Hs108|chr6 ( 488) 340 65.7 6.8e-11
CCDS78121.1 RPP21 gene_id:202658|Hs108|chr6 ( 503) 340 65.7 7e-11
CCDS34377.1 TRIM39 gene_id:56658|Hs108|chr6 ( 518) 340 65.7 7.1e-11
>>CCDS34665.1 TRIM73 gene_id:375593|Hs108|chr7 (250 aa)
initn: 1712 init1: 1679 opt: 1714 Z-score: 1501.9 bits: 285.4 E(32554): 2.5e-77
Smith-Waterman score: 1714; 98.8% identity (99.6% similar) in 250 aa overlap (1-249:1-250)
10 20 30 40 50 60
pF1KE5 MAWQVSLLELEDRLQCPICLEVFKESLMLQCGHSYCKGCLVSLSYHLDTKVRCPMCWQVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 MAWQVSLLELEDRLQCPICLEVFKESLMLQCGHSYCKGCLVSLSYHLDTKVRCPMCWQVV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 DGSSSLPNVSLAWVIEALRLPGDPEPKVCVHHRNPLSLFCEKDQELICGLCGLLGSHQHH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 DGSSSLPNVSLAWVIEALRLPGDPEPKVCVHHRNPLSLFCEKDQELICGLCGLLGSHQHH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 PVTPVSTICSRMKEELAALFSELKQEQKKVDELIAKLVNNRTRIVNESDVFSWVIRREFQ
:::::::.::::::::::::::::::::::::::::::.:::::::::::::::::::::
CCDS34 PVTPVSTVCSRMKEELAALFSELKQEQKKVDELIAKLVKNRTRIVNESDVFSWVIRREFQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 ELRHPVDEEKARCLEGIGGHTRGLVASLDMQLEQAQGTRERLAQAECVLEQFGNEDHHEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 ELRHPVDEEKARCLEGIGGHTRGLVASLDMQLEQAQGTRERLAQAECVLEQFGNEDHHEF
190 200 210 220 230 240
pF1KE5 IW-FHSMASR
:: :::::::
CCDS34 IWKFHSMASR
250
>>CCDS5545.1 TRIM74 gene_id:378108|Hs108|chr7 (250 aa)
initn: 1702 init1: 1669 opt: 1704 Z-score: 1493.3 bits: 283.8 E(32554): 7.4e-77
Smith-Waterman score: 1704; 98.4% identity (99.2% similar) in 250 aa overlap (1-249:1-250)
10 20 30 40 50 60
pF1KE5 MAWQVSLLELEDRLQCPICLEVFKESLMLQCGHSYCKGCLVSLSYHLDTKVRCPMCWQVV
:::::::::::: :::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 MAWQVSLLELEDWLQCPICLEVFKESLMLQCGHSYCKGCLVSLSYHLDTKVRCPMCWQVV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 DGSSSLPNVSLAWVIEALRLPGDPEPKVCVHHRNPLSLFCEKDQELICGLCGLLGSHQHH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 DGSSSLPNVSLAWVIEALRLPGDPEPKVCVHHRNPLSLFCEKDQELICGLCGLLGSHQHH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 PVTPVSTICSRMKEELAALFSELKQEQKKVDELIAKLVNNRTRIVNESDVFSWVIRREFQ
:::::::.::::::::::::::::::::::::::::::.:::::::::::::::::::::
CCDS55 PVTPVSTVCSRMKEELAALFSELKQEQKKVDELIAKLVKNRTRIVNESDVFSWVIRREFQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 ELRHPVDEEKARCLEGIGGHTRGLVASLDMQLEQAQGTRERLAQAECVLEQFGNEDHHEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 ELRHPVDEEKARCLEGIGGHTRGLVASLDMQLEQAQGTRERLAQAECVLEQFGNEDHHEF
190 200 210 220 230 240
pF1KE5 IW-FHSMASR
:: :::::::
CCDS55 IWKFHSMASR
250
>>CCDS34654.1 TRIM50 gene_id:135892|Hs108|chr7 (487 aa)
initn: 1567 init1: 1534 opt: 1566 Z-score: 1370.2 bits: 262.0 E(32554): 5.3e-70
Smith-Waterman score: 1566; 92.8% identity (96.4% similar) in 250 aa overlap (1-249:1-250)
10 20 30 40 50 60
pF1KE5 MAWQVSLLELEDRLQCPICLEVFKESLMLQCGHSYCKGCLVSLSYHLDTKVRCPMCWQVV
::::::: ::::::::::::::::: :::::::::::::::::: :::...:::.: :.:
CCDS34 MAWQVSLPELEDRLQCPICLEVFKEPLMLQCGHSYCKGCLVSLSCHLDAELRCPVCRQAV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 DGSSSLPNVSLAWVIEALRLPGDPEPKVCVHHRNPLSLFCEKDQELICGLCGLLGSHQHH
:::::::::::: :::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 DGSSSLPNVSLARVIEALRLPGDPEPKVCVHHRNPLSLFCEKDQELICGLCGLLGSHQHH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 PVTPVSTICSRMKEELAALFSELKQEQKKVDELIAKLVNNRTRIVNESDVFSWVIRREFQ
:::::::. ::::::::::.::::::::::::::::::::::::::::::::::::::::
CCDS34 PVTPVSTVYSRMKEELAALISELKQEQKKVDELIAKLVNNRTRIVNESDVFSWVIRREFQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 ELRHPVDEEKARCLEGIGGHTRGLVASLDMQLEQAQGTRERLAQAECVLEQFGNEDHHEF
::.: :::::::::::::::::::::::::::::::::::::::::::::::::::::.:
CCDS34 ELHHLVDEEKARCLEGIGGHTRGLVASLDMQLEQAQGTRERLAQAECVLEQFGNEDHHKF
190 200 210 220 230 240
pF1KE5 IW-FHSMASR
: :::::::
CCDS34 IRKFHSMASRAEMPQARPLEGAFSPISFKPGLHQADIKLTVWKRLFRKVLPAPEPLKLDP
250 260 270 280 290 300
>>CCDS32437.1 TRIM72 gene_id:493829|Hs108|chr16 (477 aa)
initn: 332 init1: 175 opt: 372 Z-score: 336.8 bits: 70.8 E(32554): 1.9e-12
Smith-Waterman score: 372; 28.2% identity (58.1% similar) in 248 aa overlap (10-248:8-245)
10 20 30 40 50
pF1KE5 MAWQVSLLELEDRLQCPICLEVFKESLMLQCGHSYCKGCL--VSLSYHLDTKVRCPMCWQ
:...:.::.::..: . .::::.:..:: :. : : :: :
CCDS32 MSAAPGLLHQELSCPLCLQLFDAPVTAECGHSFCRACLGRVAGEPAADGTVLCPCCQA
10 20 30 40 50
60 70 80 90 100 110
pF1KE5 VVDGSSSLPNVSLAWVIEALRLPGDPEPKVCVHHRNPLSLFCEKDQELICGLCGLLGSHQ
. .. :..:: ..:. : :. . : .: .:::..::.:. :.::.:. ::::.
CCDS32 PTRPQALSTNLQLARLVEG--LAQVPQGH-CEEHLDPLSIYCEQDRALVCGVCASLGSHR
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE5 HHPVTPVSTICSRMKEELAALFSELKQEQKKVDELIAKLVNNRTRIVNESDVFSWVIRRE
: . :.. .:.: .: .:.. . .. .: : .. ... . : .. ..
CCDS32 GHRLLPAAEAHARLKTQLPQQKLQLQEACMRKEKSVAVLEHQLVEVEETVRQFRGAVGEQ
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE5 FQELR-------HPVDEEKARCLEGIGGHTRGLVASLDMQLEQAQGTRERLAQAECVLEQ
. ..: .:.: : : : ..::. ::: : : : :::.
CCDS32 LGKMRVFLAALEGSLDREAERVRGEAGVALRRELGSLNSYLEQ-------LRQMEKVLEE
180 190 200 210 220
240
pF1KE5 FGNEDHHEFIWFHSMASR
... . ::. . ...
CCDS32 VADKPQTEFLMKYCLVTSRLQKILAESPPPARLDIQLPIISDDFKFQVWRKMFRALMPAL
230 240 250 260 270 280
>>CCDS4654.1 TRIM27 gene_id:5987|Hs108|chr6 (513 aa)
initn: 376 init1: 185 opt: 354 Z-score: 320.9 bits: 67.9 E(32554): 1.5e-11
Smith-Waterman score: 354; 32.3% identity (58.3% similar) in 192 aa overlap (10-194:10-201)
10 20 30 40 50 60
pF1KE5 MAWQVSLLELEDRLQCPICLEVFKESLMLQCGHSYCKGCLVSLSYHLDTKVRCPMCWQVV
:... ::.::. : : .::.:::. : .::. .:.: ::.: ..
CCDS46 MASGSVAECLQQETTCPVCLQYFAEPMMLDCGHNICCACLARCWGTAETNVSCPQCRETF
10 20 30 40 50 60
70 80 90 100 110
pF1KE5 DGSSSLPNVSLAWV---IEALRL--PGDP--EPKVCVHHRNPLSLFCEKDQELICGLCGL
:: :: : .. :: :. : : :: .::.::.:.::.:: :: .:
CCDS46 PQRHMRPNRHLANVTQLVKQLRTERPSGPGGEMGVCEKHREPLKLYCEEDQMPICVVCDR
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE5 LGSHQHHPVTPVSTICSRMKEELAALFSELKQEQKKVDELIAKLVNNRTRIVNESDVFSW
:. : : :. .::.. ...::. . . :. . :..... ...
CCDS46 SREHRGHSVLPLEEAVEGFKEQIQNQLDHLKRVKDLKKRRRAQGEQARAELLSLTQMERE
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE5 VIRREFQELRHPVDEEKARCLEGIGGHTRGLVASLDMQLEQAQGTRERLAQAECVLEQFG
: ::..: : . :.. : :
CCDS46 KIVWEFEQLYHSLKEHEYRLLARLEELDLAIYNSINGAITQFSCNISHLSSLIAQLEEKQ
190 200 210 220 230 240
>>CCDS31392.1 TRIM5 gene_id:85363|Hs108|chr11 (326 aa)
initn: 339 init1: 161 opt: 342 Z-score: 312.9 bits: 65.8 E(32554): 4.1e-11
Smith-Waterman score: 342; 28.1% identity (62.1% similar) in 235 aa overlap (7-230:6-240)
10 20 30 40 50
pF1KE5 MAWQVSLLELEDRLQCPICLEVFKESLMLQCGHSYCKGCLVS--LSYHLDT-KVRCPMCW
:....... ::::::.. . : :.::::.:..::.. . :: . ::.:
CCDS31 MASGILVNVKEEVTCPICLELLTQPLSLDCGHSFCQACLTANHKKSMLDKGESSCPVCR
10 20 30 40 50
60 70 80 90 100 110
pF1KE5 QVVDGSSSLPNVSLAWVIEALR-LPGDPE-PKV--CVHHRNPLSLFCEKDQELICGLCGL
. . :: .: ..: :: . .:: :: :..: . : :::..: ..:: ::
CCDS31 ISYQPENIRPNRHVANIVEKLREVKLSPEGQKVDHCARHGEKLLLFCQEDGKVICWLCER
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE5 LGSHQHHPVTPVSTICSRMKEELAALFSELKQEQKKVDELIAKLVNNRTRIVNESDVFSW
:. : . . . ... .: : . :.:.:....:: : . .... .. . .
CCDS31 SQEHRGHHTFLTEEVAREYQVKLQAALEMLRQKQQEAEELEADIREEKASWKTQIQYDKT
120 130 140 150 160 170
180 190 200 210 220
pF1KE5 VIRREFQELRHPVDEEKARCLEGIGGHTRGLVASLDMQ----LEQAQGTRERLAQAECVL
. .:..:: .: :.. :... . . .. :: . ..:.:. :: ... : :
CCDS31 NVLADFEQLRDILDWEESNELQNLEKEEEDILKSLTNSETEMVQQTQSLRELISDLEHRL
180 190 200 210 220 230
230 240
pF1KE5 EQFGNEDHHEFIWFHSMASR
.
CCDS31 QGSVMELLQGVDGVIKRTENVTLKKPETFPKNQRRVFRAPDLKGMLEVFRELTDVRRYWG
240 250 260 270 280 290
>>CCDS31394.1 TRIM5 gene_id:85363|Hs108|chr11 (347 aa)
initn: 339 init1: 161 opt: 342 Z-score: 312.6 bits: 65.8 E(32554): 4.3e-11
Smith-Waterman score: 342; 28.1% identity (62.1% similar) in 235 aa overlap (7-230:6-240)
10 20 30 40 50
pF1KE5 MAWQVSLLELEDRLQCPICLEVFKESLMLQCGHSYCKGCLVS--LSYHLDT-KVRCPMCW
:....... ::::::.. . : :.::::.:..::.. . :: . ::.:
CCDS31 MASGILVNVKEEVTCPICLELLTQPLSLDCGHSFCQACLTANHKKSMLDKGESSCPVCR
10 20 30 40 50
60 70 80 90 100 110
pF1KE5 QVVDGSSSLPNVSLAWVIEALR-LPGDPE-PKV--CVHHRNPLSLFCEKDQELICGLCGL
. . :: .: ..: :: . .:: :: :..: . : :::..: ..:: ::
CCDS31 ISYQPENIRPNRHVANIVEKLREVKLSPEGQKVDHCARHGEKLLLFCQEDGKVICWLCER
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE5 LGSHQHHPVTPVSTICSRMKEELAALFSELKQEQKKVDELIAKLVNNRTRIVNESDVFSW
:. : . . . ... .: : . :.:.:....:: : . .... .. . .
CCDS31 SQEHRGHHTFLTEEVAREYQVKLQAALEMLRQKQQEAEELEADIREEKASWKTQIQYDKT
120 130 140 150 160 170
180 190 200 210 220
pF1KE5 VIRREFQELRHPVDEEKARCLEGIGGHTRGLVASLDMQ----LEQAQGTRERLAQAECVL
. .:..:: .: :.. :... . . .. :: . ..:.:. :: ... : :
CCDS31 NVLADFEQLRDILDWEESNELQNLEKEEEDILKSLTNSETEMVQQTQSLRELISDLEHRL
180 190 200 210 220 230
230 240
pF1KE5 EQFGNEDHHEFIWFHSMASR
.
CCDS31 QGSVMELLQGVDGVIKRTENVTLKKPETFPKNQRRVFRAPDLKGMLEVFRELTDVRRYWG
240 250 260 270 280 290
>>CCDS31393.1 TRIM5 gene_id:85363|Hs108|chr11 (493 aa)
initn: 339 init1: 161 opt: 342 Z-score: 310.7 bits: 66.0 E(32554): 5.5e-11
Smith-Waterman score: 342; 28.1% identity (62.1% similar) in 235 aa overlap (7-230:6-240)
10 20 30 40 50
pF1KE5 MAWQVSLLELEDRLQCPICLEVFKESLMLQCGHSYCKGCLVS--LSYHLDT-KVRCPMCW
:....... ::::::.. . : :.::::.:..::.. . :: . ::.:
CCDS31 MASGILVNVKEEVTCPICLELLTQPLSLDCGHSFCQACLTANHKKSMLDKGESSCPVCR
10 20 30 40 50
60 70 80 90 100 110
pF1KE5 QVVDGSSSLPNVSLAWVIEALR-LPGDPE-PKV--CVHHRNPLSLFCEKDQELICGLCGL
. . :: .: ..: :: . .:: :: :..: . : :::..: ..:: ::
CCDS31 ISYQPENIRPNRHVANIVEKLREVKLSPEGQKVDHCARHGEKLLLFCQEDGKVICWLCER
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE5 LGSHQHHPVTPVSTICSRMKEELAALFSELKQEQKKVDELIAKLVNNRTRIVNESDVFSW
:. : . . . ... .: : . :.:.:....:: : . .... .. . .
CCDS31 SQEHRGHHTFLTEEVAREYQVKLQAALEMLRQKQQEAEELEADIREEKASWKTQIQYDKT
120 130 140 150 160 170
180 190 200 210 220
pF1KE5 VIRREFQELRHPVDEEKARCLEGIGGHTRGLVASLDMQ----LEQAQGTRERLAQAECVL
. .:..:: .: :.. :... . . .. :: . ..:.:. :: ... : :
CCDS31 NVLADFEQLRDILDWEESNELQNLEKEEEDILKSLTNSETEMVQQTQSLRELISDLEHRL
180 190 200 210 220 230
230 240
pF1KE5 EQFGNEDHHEFIWFHSMASR
.
CCDS31 QGSVMELLQGVDGVIKRTENVTLKKPETFPKNQRRVFRAPDLKGMLEVFRELTDVRRYWV
240 250 260 270 280 290
>>CCDS34378.1 TRIM39 gene_id:56658|Hs108|chr6 (488 aa)
initn: 349 init1: 191 opt: 340 Z-score: 309.0 bits: 65.7 E(32554): 6.8e-11
Smith-Waterman score: 340; 28.4% identity (61.6% similar) in 190 aa overlap (6-190:19-208)
10 20 30 40
pF1KE5 MAWQVSLLELEDRLQCPICLEVFKESLMLQCGHSYCKGCLVSLSYHL
.: .:. . .: .::: .:: ....:::..::.:.. :
CCDS34 MAETSLLEAGASAASTAAALENLQVEASCSVCLEYLKEPVIIECGHNFCKACITRWWEDL
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE5 DTKVRCPMCWQVVDGSSSLPNVSLAWVIEALRLPGDPEPKV-----CVHHRNPLSLFCEK
. ::.: .. : :: .:. ..: . . :. : .:.. ::::: .
CCDS34 ERDFPCPVCRKTSRYRSLRPNRQLGSMVEIAKQLQAVKRKIRDESLCPQHHEALSLFCYE
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE5 DQELICGLCGLLGSHQHHPVTPVSTICSRMKEELAALFSELKQEQKKVDELIAKLVNNRT
::: .: .:.. .:. : :.:.. ...::.: . :.:. ... . .. ..
CCDS34 DQEAVCLICAISHTHRAHTVVPLDDATQEYKEKLQKCLEPLEQKLQEITRCKSSEEKKPG
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE5 RIVNESDVFSWVIRREFQELRHPVDEEKARCLEGIGGHTRGLVASLDMQLEQAQGTRERL
.. . : :::.::.. .:::.
CCDS34 ELKRLVESRRQQILREFEELHRRLDEEQQVLLSRLEEEEQDILQRLRENAAHLGDKRRDL
190 200 210 220 230 240
>>CCDS78121.1 RPP21 gene_id:202658|Hs108|chr6 (503 aa)
initn: 349 init1: 191 opt: 340 Z-score: 308.9 bits: 65.7 E(32554): 7e-11
Smith-Waterman score: 340; 28.4% identity (61.6% similar) in 190 aa overlap (6-190:19-208)
10 20 30 40
pF1KE5 MAWQVSLLELEDRLQCPICLEVFKESLMLQCGHSYCKGCLVSLSYHL
.: .:. . .: .::: .:: ....:::..::.:.. :
CCDS78 MAETSLLEAGASAASTAAALENLQVEASCSVCLEYLKEPVIIECGHNFCKACITRWWEDL
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE5 DTKVRCPMCWQVVDGSSSLPNVSLAWVIEALRLPGDPEPKV-----CVHHRNPLSLFCEK
. ::.: .. : :: .:. ..: . . :. : .:.. ::::: .
CCDS78 ERDFPCPVCRKTSRYRSLRPNRQLGSMVEIAKQLQAVKRKIRDESLCPQHHEALSLFCYE
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE5 DQELICGLCGLLGSHQHHPVTPVSTICSRMKEELAALFSELKQEQKKVDELIAKLVNNRT
::: .: .:.. .:. : :.:.. ...::.: . :.:. ... . .. ..
CCDS78 DQEAVCLICAISHTHRAHTVVPLDDATQEYKEKLQKCLEPLEQKLQEITRCKSSEEKKPG
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE5 RIVNESDVFSWVIRREFQELRHPVDEEKARCLEGIGGHTRGLVASLDMQLEQAQGTRERL
.. . : :::.::.. .:::.
CCDS78 ELKRLVESRRQQILREFEELHRRLDEEQQVLLSRLEEEEQDILQRLRENAAHLGDKRRDL
190 200 210 220 230 240
249 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 22:39:24 2016 done: Mon Nov 7 22:39:24 2016
Total Scan time: 2.150 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]