Result of FASTA (omim) for
pFN21AE5195
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5195, 156 aa
1>>>pF1KE5195 156 - 156 aa - 156 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.0448+/-0.000295; mu= 14.3506+/- 0.018
mean_var=72.7718+/-14.580, 0's: 0 Z-trim(118.8): 65 B-trim: 44 in 1/49
Lambda= 0.150346
statistics sampled from 32041 (32117) to 32041 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.753), E-opt: 0.2 (0.377), width: 16
Scan time: 4.740
The best scores are: opt bits E(85289)
NP_115961 (OMIM: 612484) ribonuclease 7 precursor ( 156) 1092 245.0 3.6e-65
NP_612204 (OMIM: 612485) ribonuclease 8 precursor ( 154) 841 190.6 8.7e-49
XP_016877055 (OMIM: 601981) PREDICTED: ribonucleas ( 150) 587 135.5 3.3e-32
XP_016877056 (OMIM: 601981) PREDICTED: ribonucleas ( 150) 587 135.5 3.3e-32
NP_005606 (OMIM: 601981) ribonuclease K6 precursor ( 150) 587 135.5 3.3e-32
NP_002925 (OMIM: 131410) non-secretory ribonucleas ( 161) 415 98.2 5.9e-21
NP_002926 (OMIM: 131398) eosinophil cationic prote ( 160) 368 88.0 6.9e-18
NP_937875 (OMIM: 180440) ribonuclease pancreatic p ( 156) 321 77.8 7.9e-15
NP_002924 (OMIM: 180440) ribonuclease pancreatic p ( 156) 321 77.8 7.9e-15
NP_937878 (OMIM: 180440) ribonuclease pancreatic p ( 156) 321 77.8 7.9e-15
NP_937877 (OMIM: 180440) ribonuclease pancreatic p ( 156) 321 77.8 7.9e-15
NP_919412 (OMIM: 601030) ribonuclease 4 precursor ( 147) 277 68.2 5.6e-12
NP_001269121 (OMIM: 601030) ribonuclease 4 precurs ( 147) 277 68.2 5.6e-12
NP_001269122 (OMIM: 601030) ribonuclease 4 precurs ( 147) 277 68.2 5.6e-12
NP_002928 (OMIM: 601030) ribonuclease 4 precursor ( 147) 277 68.2 5.6e-12
NP_001136 (OMIM: 105850,611895) angiogenin precurs ( 147) 199 51.3 7e-07
NP_001091046 (OMIM: 105850,611895) angiogenin prec ( 147) 199 51.3 7e-07
>>NP_115961 (OMIM: 612484) ribonuclease 7 precursor [Hom (156 aa)
initn: 1092 init1: 1092 opt: 1092 Z-score: 1291.0 bits: 245.0 E(85289): 3.6e-65
Smith-Waterman score: 1092; 99.4% identity (99.4% similar) in 156 aa overlap (1-156:1-156)
10 20 30 40 50 60
pF1KE5 MAPARAGFCPLLLLLLLGLWVAEIPVSAKPKGMTSSQWFKIQHMQPSPQACNSAMKNINK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 MAPARAGFCPLLLLLLLGLWVAEIPVSAKPKGMTSSQWFKIQHMQPSPQACNSAMKNINK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 HTKRCKDLNTFLHEPFSSVAATCQTPKIACKNGDKNCHQSHGPVSLTMCKLTSGKYPNCR
:::::::::::::::::::::::::::::::::::::::::: :::::::::::::::::
NP_115 HTKRCKDLNTFLHEPFSSVAATCQTPKIACKNGDKNCHQSHGAVSLTMCKLTSGKYPNCR
70 80 90 100 110 120
130 140 150
pF1KE5 YKEKRQNKSYVVACKPPQKKDSQQFHLVPVHLDRVL
::::::::::::::::::::::::::::::::::::
NP_115 YKEKRQNKSYVVACKPPQKKDSQQFHLVPVHLDRVL
130 140 150
>>NP_612204 (OMIM: 612485) ribonuclease 8 precursor [Hom (154 aa)
initn: 898 init1: 741 opt: 841 Z-score: 996.9 bits: 190.6 E(85289): 8.7e-49
Smith-Waterman score: 841; 78.2% identity (87.8% similar) in 156 aa overlap (1-156:1-154)
10 20 30 40 50 60
pF1KE5 MAPARAGFCPLLLLLLLGLWVAEIPVSAKPKGMTSSQWFKIQHMQPSPQACNSAMKNINK
::::::: :::::::: ::::::. : :::: :::::::: ::.:::::::::::. :::
NP_612 MAPARAGCCPLLLLLL-GLWVAEVLVRAKPKDMTSSQWFKTQHVQPSPQACNSAMSIINK
10 20 30 40 50
70 80 90 100 110 120
pF1KE5 HTKRCKDLNTFLHEPFSSVAATCQTPKIACKNGDKNCHQSHGPVSLTMCKLTSGKYPNCR
.:.::::::::::::::::: :::::.:::::. :::::::::.:::: .::::::::::
NP_612 YTERCKDLNTFLHEPFSSVAITCQTPNIACKNSCKNCHQSHGPMSLTMGELTSGKYPNCR
60 70 80 90 100 110
130 140 150
pF1KE5 YKEKRQNKSYVVACKPPQKKDSQQFHLVPVHLDRVL
::::. : :.::: :::. : . :::::::.:.
NP_612 YKEKHLNTPYIVACDPPQQGDPG-YPLVPVHLDKVV
120 130 140 150
>>XP_016877055 (OMIM: 601981) PREDICTED: ribonuclease K6 (150 aa)
initn: 621 init1: 535 opt: 587 Z-score: 699.3 bits: 135.5 E(85289): 3.3e-32
Smith-Waterman score: 587; 55.7% identity (77.9% similar) in 149 aa overlap (8-156:3-150)
10 20 30 40 50 60
pF1KE5 MAPARAGFCPLLLLLLLGLWVAEIPVSAKPKGMTSSQWFKIQHMQPSPQACNSAMKNINK
.: :::::: :: :. : :: .:...::.:::.:::: :: ::..::.
XP_016 MVLCFPLLLLLLVLWGPVCPLHAWPKRLTKAHWFEIQHIQPSPLQCNRAMSGINN
10 20 30 40 50
70 80 90 100 110 120
pF1KE5 HTKRCKDLNTFLHEPFSSVAATCQTPKIACKNGDKNCHQSHGPVSLTMCKLTSGKYPNCR
.:..:: :::::. :..:::.:. .:.::: .::::: ::..: :.:::::::.::
XP_016 YTQHCKHQNTFLHDSFQNVAAVCDLLSIVCKNRRHNCHQSSKPVNMTDCRLTSGKYPQCR
60 70 80 90 100 110
130 140 150
pF1KE5 YKEKRQNKSYVVACKPPQKKDSQQFHLVPVHLDRVL
:. : : ..::: ::::.: ..::::::: .:
XP_016 YSAAAQYKFFIVACDPPQKSDPP-YKLVPVHLDSIL
120 130 140 150
>>XP_016877056 (OMIM: 601981) PREDICTED: ribonuclease K6 (150 aa)
initn: 621 init1: 535 opt: 587 Z-score: 699.3 bits: 135.5 E(85289): 3.3e-32
Smith-Waterman score: 587; 55.7% identity (77.9% similar) in 149 aa overlap (8-156:3-150)
10 20 30 40 50 60
pF1KE5 MAPARAGFCPLLLLLLLGLWVAEIPVSAKPKGMTSSQWFKIQHMQPSPQACNSAMKNINK
.: :::::: :: :. : :: .:...::.:::.:::: :: ::..::.
XP_016 MVLCFPLLLLLLVLWGPVCPLHAWPKRLTKAHWFEIQHIQPSPLQCNRAMSGINN
10 20 30 40 50
70 80 90 100 110 120
pF1KE5 HTKRCKDLNTFLHEPFSSVAATCQTPKIACKNGDKNCHQSHGPVSLTMCKLTSGKYPNCR
.:..:: :::::. :..:::.:. .:.::: .::::: ::..: :.:::::::.::
XP_016 YTQHCKHQNTFLHDSFQNVAAVCDLLSIVCKNRRHNCHQSSKPVNMTDCRLTSGKYPQCR
60 70 80 90 100 110
130 140 150
pF1KE5 YKEKRQNKSYVVACKPPQKKDSQQFHLVPVHLDRVL
:. : : ..::: ::::.: ..::::::: .:
XP_016 YSAAAQYKFFIVACDPPQKSDPP-YKLVPVHLDSIL
120 130 140 150
>>NP_005606 (OMIM: 601981) ribonuclease K6 precursor [Ho (150 aa)
initn: 621 init1: 535 opt: 587 Z-score: 699.3 bits: 135.5 E(85289): 3.3e-32
Smith-Waterman score: 587; 55.7% identity (77.9% similar) in 149 aa overlap (8-156:3-150)
10 20 30 40 50 60
pF1KE5 MAPARAGFCPLLLLLLLGLWVAEIPVSAKPKGMTSSQWFKIQHMQPSPQACNSAMKNINK
.: :::::: :: :. : :: .:...::.:::.:::: :: ::..::.
NP_005 MVLCFPLLLLLLVLWGPVCPLHAWPKRLTKAHWFEIQHIQPSPLQCNRAMSGINN
10 20 30 40 50
70 80 90 100 110 120
pF1KE5 HTKRCKDLNTFLHEPFSSVAATCQTPKIACKNGDKNCHQSHGPVSLTMCKLTSGKYPNCR
.:..:: :::::. :..:::.:. .:.::: .::::: ::..: :.:::::::.::
NP_005 YTQHCKHQNTFLHDSFQNVAAVCDLLSIVCKNRRHNCHQSSKPVNMTDCRLTSGKYPQCR
60 70 80 90 100 110
130 140 150
pF1KE5 YKEKRQNKSYVVACKPPQKKDSQQFHLVPVHLDRVL
:. : : ..::: ::::.: ..::::::: .:
NP_005 YSAAAQYKFFIVACDPPQKSDPP-YKLVPVHLDSIL
120 130 140 150
>>NP_002925 (OMIM: 131410) non-secretory ribonuclease pr (161 aa)
initn: 363 init1: 197 opt: 415 Z-score: 497.2 bits: 98.2 E(85289): 5.9e-21
Smith-Waterman score: 415; 42.0% identity (68.7% similar) in 150 aa overlap (13-156:12-161)
10 20 30 40 50 60
pF1KE5 MAPARAGFCPLLLLLLLGLWVAEIPVSAKPKGMTSSQWFKIQHMQPSPQACNSAMKNINK
::::::: ..: . .:: .: .:::. ::.. . : :..::. ::.
NP_002 MVPKLFTSQICLLLLLGLLAVEGSLHVKPPQFTWAQWFETQHINMTSQQCTNAMQVINN
10 20 30 40 50
70 80 90 100 110
pF1KE5 HTKRCKDLNTFLHEPFSSVAATCQTPKIACKNGD--KNCHQSHGPVSLTMCKLTSGK---
. .:::. :::: :..:. .: .:...: .. ::::.: . : : :.::. .
NP_002 YQRRCKNQNTFLLTTFANVVNVCGNPNMTCPSNKTRKNCHHSGSQVPLIHCNLTTPSPQN
60 70 80 90 100 110
120 130 140 150
pF1KE5 YPNCRYKEKRQNKSYVVACKP-PQKKDSQQFHLVPVHLDRVL
:::: . : :.::: :..: :. .:::::::..
NP_002 ISNCRYAQTPANMFYIVACDNRDQRRDPPQYPVVPVHLDRII
120 130 140 150 160
>>NP_002926 (OMIM: 131398) eosinophil cationic protein p (160 aa)
initn: 359 init1: 234 opt: 368 Z-score: 442.2 bits: 88.0 E(85289): 6.9e-18
Smith-Waterman score: 368; 39.6% identity (64.4% similar) in 149 aa overlap (13-156:12-160)
10 20 30 40 50 60
pF1KE5 MAPARAGFCPLLLLLLLGLWVAEIPVSAKPKGMTSSQWFKIQHMQPSPQACNSAMKNINK
::::::: .: . :.: .: .::: :::.. .: :. ::. ::.
NP_002 MVPKLFTSQICLLLLLGLMGVEGSLHARPPQFTRAQWFAIQHISLNPPRCTIAMRAINN
10 20 30 40 50
70 80 90 100 110
pF1KE5 HTKRCKDLNTFLHEPFSSVAATCQTPKIACKNGD--KNCHQSHGPVSLTMCKLTSG---K
. :::. ::::. :..:. .: . .: : .. .:::.:. : : : : . .
NP_002 YRWRCKNQNTFLRTTFANVVNVCGNQSIRCPHNRTLNNCHRSRFRVPLLHCDLINPGAQN
60 70 80 90 100 110
120 130 140 150
pF1KE5 YPNCRYKEKRQNKSYVVACKPPQKKDSQQFHLVPVHLDRVL
:: : .. . ::::: . .:: .. .:::::: ..
NP_002 ISNCTYADRPGRRFYVVACDNRDPRDSPRYPVVPVHLDTTI
120 130 140 150 160
>>NP_937875 (OMIM: 180440) ribonuclease pancreatic precu (156 aa)
initn: 345 init1: 217 opt: 321 Z-score: 387.2 bits: 77.8 E(85289): 7.9e-15
Smith-Waterman score: 321; 37.3% identity (62.7% similar) in 150 aa overlap (11-153:14-149)
10 20 30 40 50
pF1KE5 MAPARAGFCPLLLLLLLGLWVAEIPVSAKPKGMTSSQWFKIQHMQP--SPQA----C
.:.::.:: :: : .: . .. :. :::. ::.. :
NP_937 MALEKSLVRLLLLVLILLVLG-WVQ--PSLGKE---SRAKKFQRQHMDSDSSPSSSSTYC
10 20 30 40 50
60 70 80 90 100 110
pF1KE5 NSAMKNINKHTKRCKDLNTFLHEPFSSVAATCQTPKIACKNGDKNCHQSHGPVSLTMCKL
:. :. : ::: .:::.:::. .: .: :..::::. ::..:.. . .: :.:
NP_937 NQMMRRRNMTQGRCKPVNTFVHEPLVDVQNVCFQEKVTCKNGQGNCYKSNSSMHITDCRL
60 70 80 90 100 110
120 130 140 150
pF1KE5 TSG-KYPNCRYKEKRQNKSYVVACKPPQKKDSQQFHLVPVHLDRVL
:.: .:::: :. . ... .:::. ::::.:
NP_937 TNGSRYPNCAYRTSPKERHIIVACEGSP--------YVPVHFDASVEDST
120 130 140 150
>>NP_002924 (OMIM: 180440) ribonuclease pancreatic precu (156 aa)
initn: 345 init1: 217 opt: 321 Z-score: 387.2 bits: 77.8 E(85289): 7.9e-15
Smith-Waterman score: 321; 37.3% identity (62.7% similar) in 150 aa overlap (11-153:14-149)
10 20 30 40 50
pF1KE5 MAPARAGFCPLLLLLLLGLWVAEIPVSAKPKGMTSSQWFKIQHMQP--SPQA----C
.:.::.:: :: : .: . .. :. :::. ::.. :
NP_002 MALEKSLVRLLLLVLILLVLG-WVQ--PSLGKE---SRAKKFQRQHMDSDSSPSSSSTYC
10 20 30 40 50
60 70 80 90 100 110
pF1KE5 NSAMKNINKHTKRCKDLNTFLHEPFSSVAATCQTPKIACKNGDKNCHQSHGPVSLTMCKL
:. :. : ::: .:::.:::. .: .: :..::::. ::..:.. . .: :.:
NP_002 NQMMRRRNMTQGRCKPVNTFVHEPLVDVQNVCFQEKVTCKNGQGNCYKSNSSMHITDCRL
60 70 80 90 100 110
120 130 140 150
pF1KE5 TSG-KYPNCRYKEKRQNKSYVVACKPPQKKDSQQFHLVPVHLDRVL
:.: .:::: :. . ... .:::. ::::.:
NP_002 TNGSRYPNCAYRTSPKERHIIVACEGSP--------YVPVHFDASVEDST
120 130 140 150
>>NP_937878 (OMIM: 180440) ribonuclease pancreatic precu (156 aa)
initn: 345 init1: 217 opt: 321 Z-score: 387.2 bits: 77.8 E(85289): 7.9e-15
Smith-Waterman score: 321; 37.3% identity (62.7% similar) in 150 aa overlap (11-153:14-149)
10 20 30 40 50
pF1KE5 MAPARAGFCPLLLLLLLGLWVAEIPVSAKPKGMTSSQWFKIQHMQP--SPQA----C
.:.::.:: :: : .: . .. :. :::. ::.. :
NP_937 MALEKSLVRLLLLVLILLVLG-WVQ--PSLGKE---SRAKKFQRQHMDSDSSPSSSSTYC
10 20 30 40 50
60 70 80 90 100 110
pF1KE5 NSAMKNINKHTKRCKDLNTFLHEPFSSVAATCQTPKIACKNGDKNCHQSHGPVSLTMCKL
:. :. : ::: .:::.:::. .: .: :..::::. ::..:.. . .: :.:
NP_937 NQMMRRRNMTQGRCKPVNTFVHEPLVDVQNVCFQEKVTCKNGQGNCYKSNSSMHITDCRL
60 70 80 90 100 110
120 130 140 150
pF1KE5 TSG-KYPNCRYKEKRQNKSYVVACKPPQKKDSQQFHLVPVHLDRVL
:.: .:::: :. . ... .:::. ::::.:
NP_937 TNGSRYPNCAYRTSPKERHIIVACEGSP--------YVPVHFDASVEDST
120 130 140 150
156 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 22:26:47 2016 done: Mon Nov 7 22:26:47 2016
Total Scan time: 4.740 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]