Result of FASTA (omim) for
pFN21AE5166
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5166, 157 aa
1>>>pF1KE5166 157 - 157 aa - 157 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.0391+/-0.00032; mu= 9.6796+/- 0.020
mean_var=97.7280+/-19.564, 0's: 0 Z-trim(117.4): 22 B-trim: 0 in 0/58
Lambda= 0.129737
statistics sampled from 29350 (29372) to 29350 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.721), E-opt: 0.2 (0.344), width: 16
Scan time: 4.650
The best scores are: opt bits E(85289)
NP_001269881 (OMIM: 616010) COP9 signalosome compl ( 157) 1028 201.8 3.6e-52
XP_016860206 (OMIM: 616010) PREDICTED: COP9 signal ( 157) 1028 201.8 3.6e-52
NP_001269878 (OMIM: 616010) COP9 signalosome compl ( 230) 1028 202.0 4.9e-52
XP_016860205 (OMIM: 616010) PREDICTED: COP9 signal ( 264) 1028 202.0 5.5e-52
NP_073567 (OMIM: 616010) COP9 signalosome complex ( 264) 1028 202.0 5.5e-52
NP_001269880 (OMIM: 616010) COP9 signalosome compl ( 209) 1016 199.7 2.2e-51
XP_011509940 (OMIM: 616010) PREDICTED: COP9 signal ( 171) 705 141.4 6.2e-34
XP_011509941 (OMIM: 616010) PREDICTED: COP9 signal ( 171) 705 141.4 6.2e-34
XP_011509942 (OMIM: 616010) PREDICTED: COP9 signal ( 171) 705 141.4 6.2e-34
XP_006712756 (OMIM: 616010) PREDICTED: COP9 signal ( 278) 705 141.6 9e-34
NP_001295310 (OMIM: 616010) COP9 signalosome compl ( 278) 705 141.6 9e-34
NP_001269879 (OMIM: 616010) COP9 signalosome compl ( 273) 698 140.3 2.2e-33
XP_005253751 (OMIM: 616009) PREDICTED: COP9 signal ( 275) 605 122.8 3.9e-28
NP_001157567 (OMIM: 616009) COP9 signalosome compl ( 275) 605 122.8 3.9e-28
NP_001157566 (OMIM: 616009) COP9 signalosome compl ( 275) 605 122.8 3.9e-28
NP_057403 (OMIM: 616009) COP9 signalosome complex ( 275) 605 122.8 3.9e-28
NP_001157565 (OMIM: 616009) COP9 signalosome compl ( 275) 605 122.8 3.9e-28
>>NP_001269881 (OMIM: 616010) COP9 signalosome complex s (157 aa)
initn: 1028 init1: 1028 opt: 1028 Z-score: 1057.5 bits: 201.8 E(85289): 3.6e-52
Smith-Waterman score: 1028; 100.0% identity (100.0% similar) in 157 aa overlap (1-157:1-157)
10 20 30 40 50 60
pF1KE5 MKCIPYSVLLKDLEMRNLRELEDLIIEAVYTDIIQGKLDQRNQLLEVDFCIGRDIRKKDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MKCIPYSVLLKDLEMRNLRELEDLIIEAVYTDIIQGKLDQRNQLLEVDFCIGRDIRKKDI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 NNIVKTLHEWCDGCEAVLLGIEQQVLRANQYKENHNRTQQQVEAEVTNIKKTLKATASSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NNIVKTLHEWCDGCEAVLLGIEQQVLRANQYKENHNRTQQQVEAEVTNIKKTLKATASSS
70 80 90 100 110 120
130 140 150
pF1KE5 AQEMEQQLAERECPPHAEQRQPTKKMSKVKGLVSSRH
:::::::::::::::::::::::::::::::::::::
NP_001 AQEMEQQLAERECPPHAEQRQPTKKMSKVKGLVSSRH
130 140 150
>>XP_016860206 (OMIM: 616010) PREDICTED: COP9 signalosom (157 aa)
initn: 1028 init1: 1028 opt: 1028 Z-score: 1057.5 bits: 201.8 E(85289): 3.6e-52
Smith-Waterman score: 1028; 100.0% identity (100.0% similar) in 157 aa overlap (1-157:1-157)
10 20 30 40 50 60
pF1KE5 MKCIPYSVLLKDLEMRNLRELEDLIIEAVYTDIIQGKLDQRNQLLEVDFCIGRDIRKKDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MKCIPYSVLLKDLEMRNLRELEDLIIEAVYTDIIQGKLDQRNQLLEVDFCIGRDIRKKDI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 NNIVKTLHEWCDGCEAVLLGIEQQVLRANQYKENHNRTQQQVEAEVTNIKKTLKATASSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NNIVKTLHEWCDGCEAVLLGIEQQVLRANQYKENHNRTQQQVEAEVTNIKKTLKATASSS
70 80 90 100 110 120
130 140 150
pF1KE5 AQEMEQQLAERECPPHAEQRQPTKKMSKVKGLVSSRH
:::::::::::::::::::::::::::::::::::::
XP_016 AQEMEQQLAERECPPHAEQRQPTKKMSKVKGLVSSRH
130 140 150
>>NP_001269878 (OMIM: 616010) COP9 signalosome complex s (230 aa)
initn: 1028 init1: 1028 opt: 1028 Z-score: 1055.2 bits: 202.0 E(85289): 4.9e-52
Smith-Waterman score: 1028; 100.0% identity (100.0% similar) in 157 aa overlap (1-157:74-230)
10 20 30
pF1KE5 MKCIPYSVLLKDLEMRNLRELEDLIIEAVY
::::::::::::::::::::::::::::::
NP_001 YIANKESLPELSTAQQNKLKHLTIVSLASRMKCIPYSVLLKDLEMRNLRELEDLIIEAVY
50 60 70 80 90 100
40 50 60 70 80 90
pF1KE5 TDIIQGKLDQRNQLLEVDFCIGRDIRKKDINNIVKTLHEWCDGCEAVLLGIEQQVLRANQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TDIIQGKLDQRNQLLEVDFCIGRDIRKKDINNIVKTLHEWCDGCEAVLLGIEQQVLRANQ
110 120 130 140 150 160
100 110 120 130 140 150
pF1KE5 YKENHNRTQQQVEAEVTNIKKTLKATASSSAQEMEQQLAERECPPHAEQRQPTKKMSKVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YKENHNRTQQQVEAEVTNIKKTLKATASSSAQEMEQQLAERECPPHAEQRQPTKKMSKVK
170 180 190 200 210 220
pF1KE5 GLVSSRH
:::::::
NP_001 GLVSSRH
230
>>XP_016860205 (OMIM: 616010) PREDICTED: COP9 signalosom (264 aa)
initn: 1028 init1: 1028 opt: 1028 Z-score: 1054.3 bits: 202.0 E(85289): 5.5e-52
Smith-Waterman score: 1028; 100.0% identity (100.0% similar) in 157 aa overlap (1-157:108-264)
10 20 30
pF1KE5 MKCIPYSVLLKDLEMRNLRELEDLIIEAVY
::::::::::::::::::::::::::::::
XP_016 YIANKESLPELSTAQQNKLKHLTIVSLASRMKCIPYSVLLKDLEMRNLRELEDLIIEAVY
80 90 100 110 120 130
40 50 60 70 80 90
pF1KE5 TDIIQGKLDQRNQLLEVDFCIGRDIRKKDINNIVKTLHEWCDGCEAVLLGIEQQVLRANQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TDIIQGKLDQRNQLLEVDFCIGRDIRKKDINNIVKTLHEWCDGCEAVLLGIEQQVLRANQ
140 150 160 170 180 190
100 110 120 130 140 150
pF1KE5 YKENHNRTQQQVEAEVTNIKKTLKATASSSAQEMEQQLAERECPPHAEQRQPTKKMSKVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YKENHNRTQQQVEAEVTNIKKTLKATASSSAQEMEQQLAERECPPHAEQRQPTKKMSKVK
200 210 220 230 240 250
pF1KE5 GLVSSRH
:::::::
XP_016 GLVSSRH
260
>>NP_073567 (OMIM: 616010) COP9 signalosome complex subu (264 aa)
initn: 1028 init1: 1028 opt: 1028 Z-score: 1054.3 bits: 202.0 E(85289): 5.5e-52
Smith-Waterman score: 1028; 100.0% identity (100.0% similar) in 157 aa overlap (1-157:108-264)
10 20 30
pF1KE5 MKCIPYSVLLKDLEMRNLRELEDLIIEAVY
::::::::::::::::::::::::::::::
NP_073 YIANKESLPELSTAQQNKLKHLTIVSLASRMKCIPYSVLLKDLEMRNLRELEDLIIEAVY
80 90 100 110 120 130
40 50 60 70 80 90
pF1KE5 TDIIQGKLDQRNQLLEVDFCIGRDIRKKDINNIVKTLHEWCDGCEAVLLGIEQQVLRANQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_073 TDIIQGKLDQRNQLLEVDFCIGRDIRKKDINNIVKTLHEWCDGCEAVLLGIEQQVLRANQ
140 150 160 170 180 190
100 110 120 130 140 150
pF1KE5 YKENHNRTQQQVEAEVTNIKKTLKATASSSAQEMEQQLAERECPPHAEQRQPTKKMSKVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_073 YKENHNRTQQQVEAEVTNIKKTLKATASSSAQEMEQQLAERECPPHAEQRQPTKKMSKVK
200 210 220 230 240 250
pF1KE5 GLVSSRH
:::::::
NP_073 GLVSSRH
260
>>NP_001269880 (OMIM: 616010) COP9 signalosome complex s (209 aa)
initn: 1016 init1: 1016 opt: 1016 Z-score: 1043.6 bits: 199.7 E(85289): 2.2e-51
Smith-Waterman score: 1016; 99.4% identity (100.0% similar) in 156 aa overlap (2-157:54-209)
10 20 30
pF1KE5 MKCIPYSVLLKDLEMRNLRELEDLIIEAVYT
.:::::::::::::::::::::::::::::
NP_001 GSALTALISQVLEAPGVYVFGELLELANVQECIPYSVLLKDLEMRNLRELEDLIIEAVYT
30 40 50 60 70 80
40 50 60 70 80 90
pF1KE5 DIIQGKLDQRNQLLEVDFCIGRDIRKKDINNIVKTLHEWCDGCEAVLLGIEQQVLRANQY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DIIQGKLDQRNQLLEVDFCIGRDIRKKDINNIVKTLHEWCDGCEAVLLGIEQQVLRANQY
90 100 110 120 130 140
100 110 120 130 140 150
pF1KE5 KENHNRTQQQVEAEVTNIKKTLKATASSSAQEMEQQLAERECPPHAEQRQPTKKMSKVKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KENHNRTQQQVEAEVTNIKKTLKATASSSAQEMEQQLAERECPPHAEQRQPTKKMSKVKG
150 160 170 180 190 200
pF1KE5 LVSSRH
::::::
NP_001 LVSSRH
>>XP_011509940 (OMIM: 616010) PREDICTED: COP9 signalosom (171 aa)
initn: 736 init1: 705 opt: 705 Z-score: 730.3 bits: 141.4 E(85289): 6.2e-34
Smith-Waterman score: 705; 94.6% identity (99.1% similar) in 111 aa overlap (1-111:1-111)
10 20 30 40 50 60
pF1KE5 MKCIPYSVLLKDLEMRNLRELEDLIIEAVYTDIIQGKLDQRNQLLEVDFCIGRDIRKKDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MKCIPYSVLLKDLEMRNLRELEDLIIEAVYTDIIQGKLDQRNQLLEVDFCIGRDIRKKDI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 NNIVKTLHEWCDGCEAVLLGIEQQVLRANQYKENHNRTQQQVEAEVTNIKKTLKATASSS
:::::::::::::::::::::::::::::::::::::::::::::.. ...
XP_011 NNIVKTLHEWCDGCEAVLLGIEQQVLRANQYKENHNRTQQQVEAEIACFQREKRDVPLLN
70 80 90 100 110 120
130 140 150
pF1KE5 AQEMEQQLAERECPPHAEQRQPTKKMSKVKGLVSSRH
XP_011 LITTAFFWLPTSRRHSKPPHPPRLRRWSSSWLNGSVPLTLSRGSPPRRCPK
130 140 150 160 170
>>XP_011509941 (OMIM: 616010) PREDICTED: COP9 signalosom (171 aa)
initn: 736 init1: 705 opt: 705 Z-score: 730.3 bits: 141.4 E(85289): 6.2e-34
Smith-Waterman score: 705; 94.6% identity (99.1% similar) in 111 aa overlap (1-111:1-111)
10 20 30 40 50 60
pF1KE5 MKCIPYSVLLKDLEMRNLRELEDLIIEAVYTDIIQGKLDQRNQLLEVDFCIGRDIRKKDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MKCIPYSVLLKDLEMRNLRELEDLIIEAVYTDIIQGKLDQRNQLLEVDFCIGRDIRKKDI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 NNIVKTLHEWCDGCEAVLLGIEQQVLRANQYKENHNRTQQQVEAEVTNIKKTLKATASSS
:::::::::::::::::::::::::::::::::::::::::::::.. ...
XP_011 NNIVKTLHEWCDGCEAVLLGIEQQVLRANQYKENHNRTQQQVEAEIACFQREKRDVPLLN
70 80 90 100 110 120
130 140 150
pF1KE5 AQEMEQQLAERECPPHAEQRQPTKKMSKVKGLVSSRH
XP_011 LITTAFFWLPTSRRHSKPPHPPRLRRWSSSWLNGSVPLTLSRGSPPRRCPK
130 140 150 160 170
>>XP_011509942 (OMIM: 616010) PREDICTED: COP9 signalosom (171 aa)
initn: 736 init1: 705 opt: 705 Z-score: 730.3 bits: 141.4 E(85289): 6.2e-34
Smith-Waterman score: 705; 94.6% identity (99.1% similar) in 111 aa overlap (1-111:1-111)
10 20 30 40 50 60
pF1KE5 MKCIPYSVLLKDLEMRNLRELEDLIIEAVYTDIIQGKLDQRNQLLEVDFCIGRDIRKKDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MKCIPYSVLLKDLEMRNLRELEDLIIEAVYTDIIQGKLDQRNQLLEVDFCIGRDIRKKDI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 NNIVKTLHEWCDGCEAVLLGIEQQVLRANQYKENHNRTQQQVEAEVTNIKKTLKATASSS
:::::::::::::::::::::::::::::::::::::::::::::.. ...
XP_011 NNIVKTLHEWCDGCEAVLLGIEQQVLRANQYKENHNRTQQQVEAEIACFQREKRDVPLLN
70 80 90 100 110 120
130 140 150
pF1KE5 AQEMEQQLAERECPPHAEQRQPTKKMSKVKGLVSSRH
XP_011 LITTAFFWLPTSRRHSKPPHPPRLRRWSSSWLNGSVPLTLSRGSPPRRCPK
130 140 150 160 170
>>XP_006712756 (OMIM: 616010) PREDICTED: COP9 signalosom (278 aa)
initn: 736 init1: 705 opt: 705 Z-score: 727.3 bits: 141.6 E(85289): 9e-34
Smith-Waterman score: 705; 94.6% identity (99.1% similar) in 111 aa overlap (1-111:108-218)
10 20 30
pF1KE5 MKCIPYSVLLKDLEMRNLRELEDLIIEAVY
::::::::::::::::::::::::::::::
XP_006 YIANKESLPELSTAQQNKLKHLTIVSLASRMKCIPYSVLLKDLEMRNLRELEDLIIEAVY
80 90 100 110 120 130
40 50 60 70 80 90
pF1KE5 TDIIQGKLDQRNQLLEVDFCIGRDIRKKDINNIVKTLHEWCDGCEAVLLGIEQQVLRANQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TDIIQGKLDQRNQLLEVDFCIGRDIRKKDINNIVKTLHEWCDGCEAVLLGIEQQVLRANQ
140 150 160 170 180 190
100 110 120 130 140 150
pF1KE5 YKENHNRTQQQVEAEVTNIKKTLKATASSSAQEMEQQLAERECPPHAEQRQPTKKMSKVK
:::::::::::::::.. ...
XP_006 YKENHNRTQQQVEAEIACFQREKRDVPLLNLITTAFFWLPTSRRHSKPPHPPRLRRWSSS
200 210 220 230 240 250
157 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 22:13:11 2016 done: Mon Nov 7 22:13:12 2016
Total Scan time: 4.650 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]