Result of FASTA (omim) for
pFN21AE5159
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5159, 160 aa
1>>>pF1KE5159 160 - 160 aa - 160 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.4919+/-0.000308; mu= 16.5887+/- 0.019
mean_var=61.9816+/-12.010, 0's: 0 Z-trim(117.2): 25 B-trim: 0 in 0/54
Lambda= 0.162908
statistics sampled from 29058 (29085) to 29058 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.726), E-opt: 0.2 (0.341), width: 16
Scan time: 4.280
The best scores are: opt bits E(85289)
NP_002926 (OMIM: 131398) eosinophil cationic prote ( 160) 1139 275.5 2.6e-74
NP_002925 (OMIM: 131410) non-secretory ribonucleas ( 161) 798 195.3 3.5e-50
XP_016877056 (OMIM: 601981) PREDICTED: ribonucleas ( 150) 409 103.9 1.1e-22
NP_005606 (OMIM: 601981) ribonuclease K6 precursor ( 150) 409 103.9 1.1e-22
XP_016877055 (OMIM: 601981) PREDICTED: ribonucleas ( 150) 409 103.9 1.1e-22
NP_115961 (OMIM: 612484) ribonuclease 7 precursor ( 156) 377 96.4 2.1e-20
NP_612204 (OMIM: 612485) ribonuclease 8 precursor ( 154) 363 93.1 2e-19
NP_937877 (OMIM: 180440) ribonuclease pancreatic p ( 156) 217 58.8 4.4e-09
NP_937878 (OMIM: 180440) ribonuclease pancreatic p ( 156) 217 58.8 4.4e-09
NP_002924 (OMIM: 180440) ribonuclease pancreatic p ( 156) 217 58.8 4.4e-09
NP_937875 (OMIM: 180440) ribonuclease pancreatic p ( 156) 217 58.8 4.4e-09
NP_919412 (OMIM: 601030) ribonuclease 4 precursor ( 147) 203 55.4 4.1e-08
NP_002928 (OMIM: 601030) ribonuclease 4 precursor ( 147) 203 55.4 4.1e-08
NP_001269122 (OMIM: 601030) ribonuclease 4 precurs ( 147) 203 55.4 4.1e-08
NP_001269121 (OMIM: 601030) ribonuclease 4 precurs ( 147) 203 55.4 4.1e-08
NP_001136 (OMIM: 105850,611895) angiogenin precurs ( 147) 134 39.2 0.0031
NP_001091046 (OMIM: 105850,611895) angiogenin prec ( 147) 134 39.2 0.0031
>>NP_002926 (OMIM: 131398) eosinophil cationic protein p (160 aa)
initn: 1139 init1: 1139 opt: 1139 Z-score: 1455.1 bits: 275.5 E(85289): 2.6e-74
Smith-Waterman score: 1139; 99.4% identity (99.4% similar) in 160 aa overlap (1-160:1-160)
10 20 30 40 50 60
pF1KE5 MVPKLFTSQICLLLLLGLMGVEGSLHARPPQFTRAQWFAIQHISLNPPRCTIAMRAINNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MVPKLFTSQICLLLLLGLMGVEGSLHARPPQFTRAQWFAIQHISLNPPRCTIAMRAINNY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 RWRCKNQNTFLRTTFANVVNVCGNQSIRCPHNRTLNNCHRSRFRVPLLHCDLINPGAQNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 RWRCKNQNTFLRTTFANVVNVCGNQSIRCPHNRTLNNCHRSRFRVPLLHCDLINPGAQNI
70 80 90 100 110 120
130 140 150 160
pF1KE5 SNCRYADRPGRRFYVVACDNRDPRDSPRYPVVPVHLDTTI
::: ::::::::::::::::::::::::::::::::::::
NP_002 SNCTYADRPGRRFYVVACDNRDPRDSPRYPVVPVHLDTTI
130 140 150 160
>>NP_002925 (OMIM: 131410) non-secretory ribonuclease pr (161 aa)
initn: 829 init1: 731 opt: 798 Z-score: 1021.9 bits: 195.3 E(85289): 3.5e-50
Smith-Waterman score: 798; 69.6% identity (85.1% similar) in 161 aa overlap (1-160:1-161)
10 20 30 40 50 60
pF1KE5 MVPKLFTSQICLLLLLGLMGVEGSLHARPPQFTRAQWFAIQHISLNPPRCTIAMRAINNY
::::::::::::::::::..::::::..::::: :::: :::... .:: ::..::::
NP_002 MVPKLFTSQICLLLLLGLLAVEGSLHVKPPQFTWAQWFETQHINMTSQQCTNAMQVINNY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 RWRCKNQNTFLRTTFANVVNVCGNQSIRCPHNRTLNNCHRSRFRVPLLHCDLINPGAQNI
. ::::::::: :::::::::::: .. :: :.: .:::.: .:::.::.: .:. :::
NP_002 QRRCKNQNTFLLTTFANVVNVCGNPNMTCPSNKTRKNCHHSGSQVPLIHCNLTTPSPQNI
70 80 90 100 110 120
130 140 150 160
pF1KE5 SNCRYADRPGRRFYVVACDNRDPR-DSPRYPVVPVHLDTTI
::::::. :. ::.::::::: : : :.::::::::: :
NP_002 SNCRYAQTPANMFYIVACDNRDQRRDPPQYPVVPVHLDRII
130 140 150 160
>>XP_016877056 (OMIM: 601981) PREDICTED: ribonuclease K6 (150 aa)
initn: 395 init1: 271 opt: 409 Z-score: 528.2 bits: 103.9 E(85289): 1.1e-22
Smith-Waterman score: 409; 45.0% identity (64.4% similar) in 149 aa overlap (12-160:8-150)
10 20 30 40 50 60
pF1KE5 MVPKLFTSQICLLLLLGLMGVEGSLHARPPQFTRAQWFAIQHISLNPPRCTIAMRAINNY
::::: : : ::: : ..:.:.:: ::::. .: .:. :: .::::
XP_016 MVLCFPLLLLLLVLWGPVCPLHAWPKRLTKAHWFEIQHIQPSPLQCNRAMSGINNY
10 20 30 40 50
70 80 90 100 110 120
pF1KE5 RWRCKNQNTFLRTTFANVVNVCGNQSIRCPHNRTLNNCHRSRFRVPLLHCDLINPGAQNI
.::.:::::. .: ::. :: :: : . : .:::.: : . : : . .
XP_016 TQHCKHQNTFLHDSFQNVAAVCDLLSIVCKNRR--HNCHQSSKPVNMTDCRLTS---GKY
60 70 80 90 100 110
130 140 150 160
pF1KE5 SNCRYADRPGRRFYVVACDNRDPRDSPRYPVVPVHLDTTI
.:::. .:..:::: . : : : .::::::. .
XP_016 PQCRYSAAAQYKFFIVACDPPQKSDPP-YKLVPVHLDSIL
120 130 140 150
>>NP_005606 (OMIM: 601981) ribonuclease K6 precursor [Ho (150 aa)
initn: 395 init1: 271 opt: 409 Z-score: 528.2 bits: 103.9 E(85289): 1.1e-22
Smith-Waterman score: 409; 45.0% identity (64.4% similar) in 149 aa overlap (12-160:8-150)
10 20 30 40 50 60
pF1KE5 MVPKLFTSQICLLLLLGLMGVEGSLHARPPQFTRAQWFAIQHISLNPPRCTIAMRAINNY
::::: : : ::: : ..:.:.:: ::::. .: .:. :: .::::
NP_005 MVLCFPLLLLLLVLWGPVCPLHAWPKRLTKAHWFEIQHIQPSPLQCNRAMSGINNY
10 20 30 40 50
70 80 90 100 110 120
pF1KE5 RWRCKNQNTFLRTTFANVVNVCGNQSIRCPHNRTLNNCHRSRFRVPLLHCDLINPGAQNI
.::.:::::. .: ::. :: :: : . : .:::.: : . : : . .
NP_005 TQHCKHQNTFLHDSFQNVAAVCDLLSIVCKNRR--HNCHQSSKPVNMTDCRLTS---GKY
60 70 80 90 100 110
130 140 150 160
pF1KE5 SNCRYADRPGRRFYVVACDNRDPRDSPRYPVVPVHLDTTI
.:::. .:..:::: . : : : .::::::. .
NP_005 PQCRYSAAAQYKFFIVACDPPQKSDPP-YKLVPVHLDSIL
120 130 140 150
>>XP_016877055 (OMIM: 601981) PREDICTED: ribonuclease K6 (150 aa)
initn: 395 init1: 271 opt: 409 Z-score: 528.2 bits: 103.9 E(85289): 1.1e-22
Smith-Waterman score: 409; 45.0% identity (64.4% similar) in 149 aa overlap (12-160:8-150)
10 20 30 40 50 60
pF1KE5 MVPKLFTSQICLLLLLGLMGVEGSLHARPPQFTRAQWFAIQHISLNPPRCTIAMRAINNY
::::: : : ::: : ..:.:.:: ::::. .: .:. :: .::::
XP_016 MVLCFPLLLLLLVLWGPVCPLHAWPKRLTKAHWFEIQHIQPSPLQCNRAMSGINNY
10 20 30 40 50
70 80 90 100 110 120
pF1KE5 RWRCKNQNTFLRTTFANVVNVCGNQSIRCPHNRTLNNCHRSRFRVPLLHCDLINPGAQNI
.::.:::::. .: ::. :: :: : . : .:::.: : . : : . .
XP_016 TQHCKHQNTFLHDSFQNVAAVCDLLSIVCKNRR--HNCHQSSKPVNMTDCRLTS---GKY
60 70 80 90 100 110
130 140 150 160
pF1KE5 SNCRYADRPGRRFYVVACDNRDPRDSPRYPVVPVHLDTTI
.:::. .:..:::: . : : : .::::::. .
XP_016 PQCRYSAAAQYKFFIVACDPPQKSDPP-YKLVPVHLDSIL
120 130 140 150
>>NP_115961 (OMIM: 612484) ribonuclease 7 precursor [Hom (156 aa)
initn: 385 init1: 234 opt: 377 Z-score: 487.4 bits: 96.4 E(85289): 2.1e-20
Smith-Waterman score: 377; 40.3% identity (65.1% similar) in 149 aa overlap (12-160:13-156)
10 20 30 40 50
pF1KE5 MVPKLFTSQICLLLLLGLMGVEGSLHARPPQFTRAQWFAIQHISLNPPRCTIAMRAINN
::::::: .: . :.: .: .::: :::.. .: :. ::. ::.
NP_115 MAPARAGFCPLLLLLLLGLWVAEIPVSAKPKGMTSSQWFKIQHMQPSPQACNSAMKNINK
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE5 YRWRCKNQNTFLRTTFANVVNVCGNQSIRCPHNRTLNNCHRSRFRVPLLHCDLINPGAQN
. :::. ::::. :..:. .: . .: : .. .:::.:. : : : : . .
NP_115 HTKRCKDLNTFLHEPFSSVAATCQTPKIACKNGD--KNCHQSHGAVSLTMCKLTS---GK
70 80 90 100 110
120 130 140 150 160
pF1KE5 ISNCRYADRPGRRFYVVACDNRDPRDSPRYPVVPVHLDTTI
:::: .. . ::::: . .:: .. .:::::: ..
NP_115 YPNCRYKEKRQNKSYVVACKPPQKKDSQQFHLVPVHLDRVL
120 130 140 150
>>NP_612204 (OMIM: 612485) ribonuclease 8 precursor [Hom (154 aa)
initn: 374 init1: 233 opt: 363 Z-score: 469.7 bits: 93.1 E(85289): 2e-19
Smith-Waterman score: 363; 40.3% identity (64.4% similar) in 149 aa overlap (12-160:12-154)
10 20 30 40 50 60
pF1KE5 MVPKLFTSQICLLLLLGLMGVEGSLHARPPQFTRAQWFAIQHISLNPPRCTIAMRAINNY
::::::: .: ..:.: ..: .::: ::.. .: :. :: ::.:
NP_612 MAPARAGCCPLLLLLLGLWVAEVLVRAKPKDMTSSQWFKTQHVQPSPQACNSAMSIINKY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 RWRCKNQNTFLRTTFANVVNVCGNQSIRCPHNRTLNNCHRSRFRVPLLHCDLINPGAQNI
:::. ::::. :..:. .: . .: : . . .:::.:. . : .: . .
NP_612 TERCKDLNTFLHEPFSSVAITCQTPNIACKN--SCKNCHQSHGPMSLTMGELTS---GKY
70 80 90 100 110
130 140 150 160
pF1KE5 SNCRYADRPGRRFYVVACDNRDPRDSPRYPVVPVHLDTTI
:::: .. :.:::: . : : ::.:::::: ..
NP_612 PNCRYKEKHLNTPYIVACDPPQQGD-PGYPLVPVHLDKVV
120 130 140 150
>>NP_937877 (OMIM: 180440) ribonuclease pancreatic precu (156 aa)
initn: 255 init1: 122 opt: 217 Z-score: 284.1 bits: 58.8 E(85289): 4.4e-09
Smith-Waterman score: 244; 31.5% identity (56.2% similar) in 162 aa overlap (5-160:3-152)
10 20 30 40 50
pF1KE5 MVPKLFTSQICLLLLLGLMGVEGSLHARPPQFTRAQWFAIQHI-SLNPPR-----CTIAM
: : . ::::. .. : : .. . .::. : ::. : . : :. :
NP_937 MALEKSLVRLLLLVLILLVLGWVQPSLGKESRAKKFQRQHMDSDSSPSSSSTYCNQMM
10 20 30 40 50
60 70 80 90 100 110
pF1KE5 RAINNYRWRCKNQNTFLRTTFANVVNVCGNQSIRCPHNRTLNNCHRSRFRVPLLHCDLIN
: : . ::: :::.. ...: ::: .... : ... .::..: . . : : :
NP_937 RRRNMTQGRCKPVNTFVHEPLVDVQNVCFQEKVTCKNGQ--GNCYKSNSSMHITDCRLTN
60 70 80 90 100 110
120 130 140 150 160
pF1KE5 PGAQNISNCRYADRPGRRFYVVACDNRDPRDSPRYPVVPVHLDTTI
:.. :: : : .: .:::.. : ::::.:...
NP_937 -GSR-YPNCAYRTSPKERHIIVACEGS--------PYVPVHFDASVEDST
120 130 140 150
>>NP_937878 (OMIM: 180440) ribonuclease pancreatic precu (156 aa)
initn: 255 init1: 122 opt: 217 Z-score: 284.1 bits: 58.8 E(85289): 4.4e-09
Smith-Waterman score: 244; 31.5% identity (56.2% similar) in 162 aa overlap (5-160:3-152)
10 20 30 40 50
pF1KE5 MVPKLFTSQICLLLLLGLMGVEGSLHARPPQFTRAQWFAIQHI-SLNPPR-----CTIAM
: : . ::::. .. : : .. . .::. : ::. : . : :. :
NP_937 MALEKSLVRLLLLVLILLVLGWVQPSLGKESRAKKFQRQHMDSDSSPSSSSTYCNQMM
10 20 30 40 50
60 70 80 90 100 110
pF1KE5 RAINNYRWRCKNQNTFLRTTFANVVNVCGNQSIRCPHNRTLNNCHRSRFRVPLLHCDLIN
: : . ::: :::.. ...: ::: .... : ... .::..: . . : : :
NP_937 RRRNMTQGRCKPVNTFVHEPLVDVQNVCFQEKVTCKNGQ--GNCYKSNSSMHITDCRLTN
60 70 80 90 100 110
120 130 140 150 160
pF1KE5 PGAQNISNCRYADRPGRRFYVVACDNRDPRDSPRYPVVPVHLDTTI
:.. :: : : .: .:::.. : ::::.:...
NP_937 -GSR-YPNCAYRTSPKERHIIVACEGS--------PYVPVHFDASVEDST
120 130 140 150
>>NP_002924 (OMIM: 180440) ribonuclease pancreatic precu (156 aa)
initn: 255 init1: 122 opt: 217 Z-score: 284.1 bits: 58.8 E(85289): 4.4e-09
Smith-Waterman score: 244; 31.5% identity (56.2% similar) in 162 aa overlap (5-160:3-152)
10 20 30 40 50
pF1KE5 MVPKLFTSQICLLLLLGLMGVEGSLHARPPQFTRAQWFAIQHI-SLNPPR-----CTIAM
: : . ::::. .. : : .. . .::. : ::. : . : :. :
NP_002 MALEKSLVRLLLLVLILLVLGWVQPSLGKESRAKKFQRQHMDSDSSPSSSSTYCNQMM
10 20 30 40 50
60 70 80 90 100 110
pF1KE5 RAINNYRWRCKNQNTFLRTTFANVVNVCGNQSIRCPHNRTLNNCHRSRFRVPLLHCDLIN
: : . ::: :::.. ...: ::: .... : ... .::..: . . : : :
NP_002 RRRNMTQGRCKPVNTFVHEPLVDVQNVCFQEKVTCKNGQ--GNCYKSNSSMHITDCRLTN
60 70 80 90 100 110
120 130 140 150 160
pF1KE5 PGAQNISNCRYADRPGRRFYVVACDNRDPRDSPRYPVVPVHLDTTI
:.. :: : : .: .:::.. : ::::.:...
NP_002 -GSR-YPNCAYRTSPKERHIIVACEGS--------PYVPVHFDASVEDST
120 130 140 150
160 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 22:09:37 2016 done: Mon Nov 7 22:09:38 2016
Total Scan time: 4.280 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]