Result of FASTA (omim) for
pFN21AE5130
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5130, 150 aa
1>>>pF1KE5130 150 - 150 aa - 150 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.5166+/-0.00026; mu= 13.0884+/- 0.016
mean_var=90.7402+/-17.848, 0's: 0 Z-trim(122.2): 193 B-trim: 342 in 1/57
Lambda= 0.134640
statistics sampled from 39744 (39942) to 39744 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.821), E-opt: 0.2 (0.468), width: 16
Scan time: 5.540
The best scores are: opt bits E(85289)
XP_011520954 (OMIM: 608387) PREDICTED: zinc finger ( 285) 206 48.7 7.8e-06
NP_001333508 (OMIM: 601260) zinc finger protein wi ( 321) 205 48.6 9.8e-06
NP_001128127 (OMIM: 608387) zinc finger protein 21 ( 459) 206 48.9 1.1e-05
NP_004211 (OMIM: 608387) zinc finger protein 213 [ ( 459) 206 48.9 1.1e-05
NP_001333510 (OMIM: 601260) zinc finger protein wi ( 563) 205 48.8 1.5e-05
NP_003430 (OMIM: 601260) zinc finger protein with ( 563) 205 48.8 1.5e-05
XP_011514861 (OMIM: 601260) PREDICTED: zinc finger ( 563) 205 48.8 1.5e-05
NP_001253962 (OMIM: 194550) myeloid zinc finger 1 ( 290) 199 47.4 2e-05
XP_011525566 (OMIM: 194550) PREDICTED: myeloid zin ( 764) 203 48.5 2.4e-05
XP_005259261 (OMIM: 194550) PREDICTED: myeloid zin ( 775) 203 48.5 2.5e-05
NP_003413 (OMIM: 194550) myeloid zinc finger 1 iso ( 734) 199 47.7 4.1e-05
NP_932172 (OMIM: 194550) myeloid zinc finger 1 iso ( 734) 199 47.7 4.1e-05
XP_011513113 (OMIM: 610794) PREDICTED: zinc finger ( 406) 194 46.5 5.1e-05
XP_011513115 (OMIM: 610794) PREDICTED: zinc finger ( 406) 194 46.5 5.1e-05
XP_011513109 (OMIM: 610794) PREDICTED: zinc finger ( 406) 194 46.5 5.1e-05
XP_005249353 (OMIM: 610794) PREDICTED: zinc finger ( 406) 194 46.5 5.1e-05
NP_112161 (OMIM: 610794) zinc finger and SCAN doma ( 406) 194 46.5 5.1e-05
NP_665916 (OMIM: 610794) zinc finger and SCAN doma ( 406) 194 46.5 5.1e-05
XP_011513110 (OMIM: 610794) PREDICTED: zinc finger ( 406) 194 46.5 5.1e-05
NP_001230170 (OMIM: 610794) zinc finger and SCAN d ( 406) 194 46.5 5.1e-05
XP_011513111 (OMIM: 610794) PREDICTED: zinc finger ( 406) 194 46.5 5.1e-05
NP_001128688 (OMIM: 610794) zinc finger and SCAN d ( 406) 194 46.5 5.1e-05
XP_005249352 (OMIM: 610794) PREDICTED: zinc finger ( 406) 194 46.5 5.1e-05
XP_016866685 (OMIM: 610794) PREDICTED: zinc finger ( 406) 194 46.5 5.1e-05
NP_001128687 (OMIM: 610794) zinc finger and SCAN d ( 406) 194 46.5 5.1e-05
XP_011513114 (OMIM: 610794) PREDICTED: zinc finger ( 406) 194 46.5 5.1e-05
NP_001333509 (OMIM: 601260) zinc finger protein wi ( 527) 194 46.6 6.2e-05
NP_001273983 (OMIM: 601260) zinc finger protein wi ( 527) 194 46.6 6.2e-05
NP_001295052 (OMIM: 194534) zinc finger protein 24 ( 193) 186 44.7 8.7e-05
NP_443155 (OMIM: 615254) SCAN domain-containing pr (1325) 196 47.4 9.4e-05
XP_005258398 (OMIM: 194534) PREDICTED: zinc finger ( 368) 186 44.9 0.00014
NP_008896 (OMIM: 194534) zinc finger protein 24 is ( 368) 186 44.9 0.00014
XP_016866755 (OMIM: 602240) PREDICTED: zinc finger ( 578) 186 45.1 0.0002
NP_001265048 (OMIM: 602240) zinc finger protein wi ( 578) 186 45.1 0.0002
NP_006289 (OMIM: 602240) zinc finger protein with ( 578) 186 45.1 0.0002
XP_011513172 (OMIM: 602240) PREDICTED: zinc finger ( 578) 186 45.1 0.0002
XP_016867413 (OMIM: 611272) PREDICTED: zinc finger ( 766) 185 45.0 0.00028
XP_016867412 (OMIM: 611272) PREDICTED: zinc finger ( 766) 185 45.0 0.00028
NP_001305012 (OMIM: 611272) zinc finger protein wi ( 766) 185 45.0 0.00028
XP_016867409 (OMIM: 611272) PREDICTED: zinc finger ( 838) 185 45.0 0.00029
XP_016867410 (OMIM: 611272) PREDICTED: zinc finger ( 838) 185 45.0 0.00029
XP_016867411 (OMIM: 611272) PREDICTED: zinc finger ( 838) 185 45.0 0.00029
XP_016867407 (OMIM: 611272) PREDICTED: zinc finger ( 839) 185 45.0 0.0003
NP_001305011 (OMIM: 611272) zinc finger protein wi ( 839) 185 45.0 0.0003
NP_659570 (OMIM: 611272) zinc finger protein with ( 839) 185 45.0 0.0003
XP_016867408 (OMIM: 611272) PREDICTED: zinc finger ( 839) 185 45.0 0.0003
NP_055384 (OMIM: 611272) zinc finger protein with ( 839) 185 45.0 0.0003
NP_001027463 (OMIM: 603900) zinc finger protein 17 ( 234) 177 43.0 0.00034
NP_003441 (OMIM: 603900) zinc finger protein 174 i ( 407) 177 43.2 0.00051
NP_115723 (OMIM: 609601) zinc finger protein 397 i ( 275) 174 42.5 0.00057
>>XP_011520954 (OMIM: 608387) PREDICTED: zinc finger pro (285 aa)
initn: 353 init1: 144 opt: 206 Z-score: 225.7 bits: 48.7 E(85289): 7.8e-06
Smith-Waterman score: 283; 42.0% identity (67.2% similar) in 131 aa overlap (9-130:1-125)
10 20 30 40 50 60
pF1KE5 MMAADIPRVTTPLSSLVQVPQEEDRQEEEVTTMILEDDSWVQEAVLQEDGPESEPFPQSA
...:: . :.: : : . . .::.:: ::.. .::: .:: :
XP_011 MAAPLEAQDQAPGEG----EGLLIVKVEDSSWEQESAQHEDGRDSEACRQRF
10 20 30 40
70 80 90 100 110
pF1KE5 GKGGPQEEVTRGPQGALGRLRELCRRWLRPEVHTKEQML---------TMLPKEIQAWLQ
. . ..::. :...: ::: ::::::..::::.: :.:: :::.:..
XP_011 RQFCYGD--VHGPHEAFSQLWELCCRWLRPELRTKEQILELLVLEQFLTVLPGEIQGWVR
50 60 70 80 90 100
120 130 140 150
pF1KE5 EHRPESSEEAAALVEDLTQTLQDSAVAVFASLPVEVTSL
:..: :.:::.:::::: .
XP_011 EQHPGSGEEAVALVEDLQKQPVKAWRQDVPSEEAEPEAAGRGSQATGPPPTVGARRRPSV
110 120 130 140 150 160
>>NP_001333508 (OMIM: 601260) zinc finger protein with K (321 aa)
initn: 301 init1: 163 opt: 205 Z-score: 224.0 bits: 48.6 E(85289): 9.8e-06
Smith-Waterman score: 313; 43.4% identity (65.1% similar) in 152 aa overlap (1-137:1-143)
10 20 30 40 50
pF1KE5 MMAADIPRVTTPLSSLVQVPQEED-----RQEEEVTTMILEDDSWVQEAVLQEDGP-ESE
::.:. : .: :: :. ::.: . ::: :: : :...::. : . :
NP_001 MMTAE-SREATGLSP--QAAQEKDGIVIVKVEEEDE----EDHMWGQDSTLQDTPPPDPE
10 20 30 40 50
60 70 80 90 100
pF1KE5 PFPQSAGKGGPQEEVTRGPQGALGRLRELCRRWLRPEVHTKEQML---------TMLPKE
: : . :. : ::. ::.::.:::..:::::..::::.: ..::::
NP_001 IFRQRFRRFCYQN--TFGPREALSRLKELCHQWLRPEINTKEQILELLVLEQFLSILPKE
60 70 80 90 100 110
110 120 130 140 150
pF1KE5 IQAWLQEHRPESSEEAAALVEDLTQTLQDSAVAVFASLPVEVTSL
.:.::::.::.:.:::..:.::: :. . :
NP_001 LQVWLQEYRPDSGEEAVTLLEDLELDLSGQQVPGQVHGPEMLARGMVPLDPVQESSSFDL
120 130 140 150 160 170
NP_001 HHEATQSHFKHSSRKPRLLQSRALPAAHIPAPPHEGSPRDQAMASALFTADSQAMVKIED
180 190 200 210 220 230
>>NP_001128127 (OMIM: 608387) zinc finger protein 213 [H (459 aa)
initn: 353 init1: 144 opt: 206 Z-score: 222.9 bits: 48.9 E(85289): 1.1e-05
Smith-Waterman score: 283; 42.0% identity (67.2% similar) in 131 aa overlap (9-130:1-125)
10 20 30 40 50 60
pF1KE5 MMAADIPRVTTPLSSLVQVPQEEDRQEEEVTTMILEDDSWVQEAVLQEDGPESEPFPQSA
...:: . :.: : : . . .::.:: ::.. .::: .:: :
NP_001 MAAPLEAQDQAPGEG----EGLLIVKVEDSSWEQESAQHEDGRDSEACRQRF
10 20 30 40
70 80 90 100 110
pF1KE5 GKGGPQEEVTRGPQGALGRLRELCRRWLRPEVHTKEQML---------TMLPKEIQAWLQ
. . ..::. :...: ::: ::::::..::::.: :.:: :::.:..
NP_001 RQFCYGD--VHGPHEAFSQLWELCCRWLRPELRTKEQILELLVLEQFLTVLPGEIQGWVR
50 60 70 80 90 100
120 130 140 150
pF1KE5 EHRPESSEEAAALVEDLTQTLQDSAVAVFASLPVEVTSL
:..: :.:::.:::::: .
NP_001 EQHPGSGEEAVALVEDLQKQPVKAWRQDVPSEEAEPEAAGRGSQATGPPPTVGARRRPSV
110 120 130 140 150 160
>>NP_004211 (OMIM: 608387) zinc finger protein 213 [Homo (459 aa)
initn: 353 init1: 144 opt: 206 Z-score: 222.9 bits: 48.9 E(85289): 1.1e-05
Smith-Waterman score: 283; 42.0% identity (67.2% similar) in 131 aa overlap (9-130:1-125)
10 20 30 40 50 60
pF1KE5 MMAADIPRVTTPLSSLVQVPQEEDRQEEEVTTMILEDDSWVQEAVLQEDGPESEPFPQSA
...:: . :.: : : . . .::.:: ::.. .::: .:: :
NP_004 MAAPLEAQDQAPGEG----EGLLIVKVEDSSWEQESAQHEDGRDSEACRQRF
10 20 30 40
70 80 90 100 110
pF1KE5 GKGGPQEEVTRGPQGALGRLRELCRRWLRPEVHTKEQML---------TMLPKEIQAWLQ
. . ..::. :...: ::: ::::::..::::.: :.:: :::.:..
NP_004 RQFCYGD--VHGPHEAFSQLWELCCRWLRPELRTKEQILELLVLEQFLTVLPGEIQGWVR
50 60 70 80 90 100
120 130 140 150
pF1KE5 EHRPESSEEAAALVEDLTQTLQDSAVAVFASLPVEVTSL
:..: :.:::.:::::: .
NP_004 EQHPGSGEEAVALVEDLQKQPVKAWRQDVPSEEAEPEAAGRGSQATGPPPTVGARRRPSV
110 120 130 140 150 160
>>NP_001333510 (OMIM: 601260) zinc finger protein with K (563 aa)
initn: 301 init1: 163 opt: 205 Z-score: 220.7 bits: 48.8 E(85289): 1.5e-05
Smith-Waterman score: 313; 43.4% identity (65.1% similar) in 152 aa overlap (1-137:1-143)
10 20 30 40 50
pF1KE5 MMAADIPRVTTPLSSLVQVPQEED-----RQEEEVTTMILEDDSWVQEAVLQEDGP-ESE
::.:. : .: :: :. ::.: . ::: :: : :...::. : . :
NP_001 MMTAE-SREATGLSP--QAAQEKDGIVIVKVEEEDE----EDHMWGQDSTLQDTPPPDPE
10 20 30 40 50
60 70 80 90 100
pF1KE5 PFPQSAGKGGPQEEVTRGPQGALGRLRELCRRWLRPEVHTKEQML---------TMLPKE
: : . :. : ::. ::.::.:::..:::::..::::.: ..::::
NP_001 IFRQRFRRFCYQN--TFGPREALSRLKELCHQWLRPEINTKEQILELLVLEQFLSILPKE
60 70 80 90 100 110
110 120 130 140 150
pF1KE5 IQAWLQEHRPESSEEAAALVEDLTQTLQDSAVAVFASLPVEVTSL
.:.::::.::.:.:::..:.::: :. . :
NP_001 LQVWLQEYRPDSGEEAVTLLEDLELDLSGQQVPGQVHGPEMLARGMVPLDPVQESSSFDL
120 130 140 150 160 170
NP_001 HHEATQSHFKHSSRKPRLLQSRALPAAHIPAPPHEGSPRDQAMASALFTADSQAMVKIED
180 190 200 210 220 230
>>NP_003430 (OMIM: 601260) zinc finger protein with KRAB (563 aa)
initn: 301 init1: 163 opt: 205 Z-score: 220.7 bits: 48.8 E(85289): 1.5e-05
Smith-Waterman score: 313; 43.4% identity (65.1% similar) in 152 aa overlap (1-137:1-143)
10 20 30 40 50
pF1KE5 MMAADIPRVTTPLSSLVQVPQEED-----RQEEEVTTMILEDDSWVQEAVLQEDGP-ESE
::.:. : .: :: :. ::.: . ::: :: : :...::. : . :
NP_003 MMTAE-SREATGLSP--QAAQEKDGIVIVKVEEEDE----EDHMWGQDSTLQDTPPPDPE
10 20 30 40 50
60 70 80 90 100
pF1KE5 PFPQSAGKGGPQEEVTRGPQGALGRLRELCRRWLRPEVHTKEQML---------TMLPKE
: : . :. : ::. ::.::.:::..:::::..::::.: ..::::
NP_003 IFRQRFRRFCYQN--TFGPREALSRLKELCHQWLRPEINTKEQILELLVLEQFLSILPKE
60 70 80 90 100 110
110 120 130 140 150
pF1KE5 IQAWLQEHRPESSEEAAALVEDLTQTLQDSAVAVFASLPVEVTSL
.:.::::.::.:.:::..:.::: :. . :
NP_003 LQVWLQEYRPDSGEEAVTLLEDLELDLSGQQVPGQVHGPEMLARGMVPLDPVQESSSFDL
120 130 140 150 160 170
NP_003 HHEATQSHFKHSSRKPRLLQSRALPAAHIPAPPHEGSPRDQAMASALFTADSQAMVKIED
180 190 200 210 220 230
>>XP_011514861 (OMIM: 601260) PREDICTED: zinc finger pro (563 aa)
initn: 301 init1: 163 opt: 205 Z-score: 220.7 bits: 48.8 E(85289): 1.5e-05
Smith-Waterman score: 313; 43.4% identity (65.1% similar) in 152 aa overlap (1-137:1-143)
10 20 30 40 50
pF1KE5 MMAADIPRVTTPLSSLVQVPQEED-----RQEEEVTTMILEDDSWVQEAVLQEDGP-ESE
::.:. : .: :: :. ::.: . ::: :: : :...::. : . :
XP_011 MMTAE-SREATGLSP--QAAQEKDGIVIVKVEEEDE----EDHMWGQDSTLQDTPPPDPE
10 20 30 40 50
60 70 80 90 100
pF1KE5 PFPQSAGKGGPQEEVTRGPQGALGRLRELCRRWLRPEVHTKEQML---------TMLPKE
: : . :. : ::. ::.::.:::..:::::..::::.: ..::::
XP_011 IFRQRFRRFCYQN--TFGPREALSRLKELCHQWLRPEINTKEQILELLVLEQFLSILPKE
60 70 80 90 100 110
110 120 130 140 150
pF1KE5 IQAWLQEHRPESSEEAAALVEDLTQTLQDSAVAVFASLPVEVTSL
.:.::::.::.:.:::..:.::: :. . :
XP_011 LQVWLQEYRPDSGEEAVTLLEDLELDLSGQQVPGQVHGPEMLARGMVPLDPVQESSSFDL
120 130 140 150 160 170
XP_011 HHEATQSHFKHSSRKPRLLQSRALPAAHIPAPPHEGSPRDQAMASALFTADSQAMVKIED
180 190 200 210 220 230
>>NP_001253962 (OMIM: 194550) myeloid zinc finger 1 isof (290 aa)
initn: 322 init1: 165 opt: 199 Z-score: 218.2 bits: 47.4 E(85289): 2e-05
Smith-Waterman score: 267; 49.1% identity (66.1% similar) in 112 aa overlap (27-128:15-122)
10 20 30 40 50
pF1KE5 MMAADIPRVTTPLSSLVQVPQEEDRQEEEVTTMI-LEDDSWVQEAVLQEDGPESEPFPQS
:.: .:. :::. ::.: . :::. .
NP_001 MRPAVLGSPDRAPPEDEGPVMVKLEDSEEEGEAALWDPGPEAARLRFR
10 20 30 40
60 70 80 90 100 110
pF1KE5 AGKGGPQEEVTRGPQGALGRLRELCRRWLRPEVHTKEQMLTML---------PKEIQAWL
. ::.: ::: ::..::::::.::::::..::::: .: : :::: .
NP_001 CFR---YEEAT-GPQEALAQLRELCRQWLRPEVRSKEQMLELLVLEQFLGALPPEIQARV
50 60 70 80 90 100
120 130 140 150
pF1KE5 QEHRPESSEEAAALVEDLTQTLQDSAVAVFASLPVEVTSL
: .:: : :::::::. :
NP_001 QGQRPGSPEEAAALVDGLRREPGGPRRWVTVQVQGQEVLSEKMEPSSFQPLPETEPPTPE
110 120 130 140 150 160
>>XP_011525566 (OMIM: 194550) PREDICTED: myeloid zinc fi (764 aa)
initn: 304 init1: 165 opt: 203 Z-score: 216.8 bits: 48.5 E(85289): 2.4e-05
Smith-Waterman score: 271; 43.6% identity (61.7% similar) in 133 aa overlap (6-128:24-152)
10 20 30 40
pF1KE5 MMAADIPRVTTPLSSLVQVPQEEDRQEEEVTTMI-LEDDSWV
:: .. . : .. :.: .:. :::.
XP_011 MPTHGFEAGSMGRSGQEGRHWPQIPDLVPSMRPAVLGSPDRAPPEDEGPVMVKLEDSEEE
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE5 QEAVLQEDGPESEPFPQSAGKGGPQEEVTRGPQGALGRLRELCRRWLRPEVHTKEQMLTM
::.: . :::. . . ::.: ::: ::..::::::.::::::..::::: .
XP_011 GEAALWDPGPEAARLRFRCFR---YEEAT-GPQEALAQLRELCRQWLRPEVRSKEQMLEL
70 80 90 100 110
110 120 130 140 150
pF1KE5 L---------PKEIQAWLQEHRPESSEEAAALVEDLTQTLQDSAVAVFASLPVEVTSL
: : :::: .: .:: : :::::::. :
XP_011 LVLEQFLGALPPEIQARVQGQRPGSPEEAAALVDGLRREPGGPRRWVTVQVQGQEVLSEK
120 130 140 150 160 170
XP_011 MEPSSFQPLPETEPPTPEPGPKTPPRTMQESPLGLQVKEESEVTEDSDFLESGPLAATQE
180 190 200 210 220 230
>>XP_005259261 (OMIM: 194550) PREDICTED: myeloid zinc fi (775 aa)
initn: 304 init1: 165 opt: 203 Z-score: 216.8 bits: 48.5 E(85289): 2.5e-05
Smith-Waterman score: 271; 43.6% identity (61.7% similar) in 133 aa overlap (6-128:35-163)
10 20 30
pF1KE5 MMAADIPRVTTPLSSLVQVPQEEDRQEEEVTTMI-
:: .. . : .. :.: .:.
XP_005 CHPLHKRRFLPKAAAAEGTARGGRGRHWPQIPDLVPSMRPAVLGSPDRAPPEDEGPVMVK
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE5 LEDDSWVQEAVLQEDGPESEPFPQSAGKGGPQEEVTRGPQGALGRLRELCRRWLRPEVHT
:::. ::.: . :::. . . ::.: ::: ::..::::::.::::::..
XP_005 LEDSEEEGEAALWDPGPEAARLRFRCFR---YEEAT-GPQEALAQLRELCRQWLRPEVRS
70 80 90 100 110 120
100 110 120 130 140
pF1KE5 KEQMLTML---------PKEIQAWLQEHRPESSEEAAALVEDLTQTLQDSAVAVFASLPV
::::: .: : :::: .: .:: : :::::::. :
XP_005 KEQMLELLVLEQFLGALPPEIQARVQGQRPGSPEEAAALVDGLRREPGGPRRWVTVQVQG
130 140 150 160 170 180
150
pF1KE5 EVTSL
XP_005 QEVLSEKMEPSSFQPLPETEPPTPEPGPKTPPRTMQESPLGLQVKEESEVTEDSDFLESG
190 200 210 220 230 240
150 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 21:39:57 2016 done: Mon Nov 7 21:39:58 2016
Total Scan time: 5.540 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]