Result of FASTA (omim) for
pFN21AE5129
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5129, 164 aa
1>>>pF1KE5129 164 - 164 aa - 164 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.8324+/-0.00037; mu= 14.0308+/- 0.023
mean_var=57.5177+/-11.894, 0's: 0 Z-trim(111.9): 81 B-trim: 0 in 0/50
Lambda= 0.169112
statistics sampled from 20538 (20624) to 20538 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.629), E-opt: 0.2 (0.242), width: 16
Scan time: 4.980
The best scores are: opt bits E(85289)
NP_001137504 (OMIM: 608608) peptidyl-prolyl cis-tr ( 164) 1074 270.2 1.1e-72
NP_066953 (OMIM: 123840) peptidyl-prolyl cis-trans ( 165) 966 243.8 9.1e-65
NP_005720 (OMIM: 604486) peptidyl-prolyl cis-trans ( 207) 778 198.0 7e-51
XP_016855541 (OMIM: 602435) PREDICTED: peptidyl-pr ( 217) 701 179.3 3.3e-45
NP_006103 (OMIM: 602435) peptidyl-prolyl cis-trans ( 301) 701 179.3 4.3e-45
XP_006710353 (OMIM: 602435) PREDICTED: peptidyl-pr ( 288) 698 178.6 6.9e-45
XP_011509880 (OMIM: 601181,608033) PREDICTED: E3 S (2281) 659 169.6 2.7e-41
XP_005264064 (OMIM: 601181,608033) PREDICTED: E3 S (2282) 659 169.6 2.7e-41
XP_011509878 (OMIM: 601181,608033) PREDICTED: E3 S (3199) 659 169.7 3.6e-41
NP_006258 (OMIM: 601181,608033) E3 SUMO-protein li (3224) 659 169.7 3.6e-41
XP_005264062 (OMIM: 601181,608033) PREDICTED: E3 S (3232) 659 169.7 3.7e-41
XP_005264061 (OMIM: 601181,608033) PREDICTED: E3 S (3232) 659 169.7 3.7e-41
XP_005264060 (OMIM: 601181,608033) PREDICTED: E3 S (3250) 659 169.7 3.7e-41
XP_011509877 (OMIM: 601181,608033) PREDICTED: E3 S (3257) 659 169.7 3.7e-41
XP_005264059 (OMIM: 601181,608033) PREDICTED: E3 S (3258) 659 169.7 3.7e-41
XP_011538803 (OMIM: 602435) PREDICTED: peptidyl-pr ( 230) 635 163.2 2.4e-40
NP_982281 (OMIM: 602435) peptidyl-prolyl cis-trans ( 296) 635 163.2 3e-40
NP_001181936 (OMIM: 602435) peptidyl-prolyl cis-tr ( 314) 635 163.3 3.1e-40
XP_016855540 (OMIM: 602435) PREDICTED: peptidyl-pr ( 314) 635 163.3 3.1e-40
NP_001306222 (OMIM: 602435) peptidyl-prolyl cis-tr ( 283) 632 162.5 4.8e-40
XP_006710352 (OMIM: 602435) PREDICTED: peptidyl-pr ( 301) 632 162.5 5e-40
NP_001287910 (OMIM: 123840) peptidyl-prolyl cis-tr ( 105) 622 159.8 1.2e-39
XP_005269436 (OMIM: 604486) PREDICTED: peptidyl-pr ( 201) 597 153.9 1.3e-37
NP_000933 (OMIM: 123841,259440) peptidyl-prolyl ci ( 216) 582 150.2 1.8e-36
NP_005029 (OMIM: 601753) peptidyl-prolyl cis-trans ( 370) 578 149.4 5.5e-36
NP_000934 (OMIM: 123842) peptidyl-prolyl cis-trans ( 212) 549 142.2 4.7e-34
XP_005270419 (OMIM: 606095) PREDICTED: peptidyl-pr ( 177) 544 140.9 9.5e-34
NP_006338 (OMIM: 606095) peptidyl-prolyl cis-trans ( 177) 544 140.9 9.5e-34
XP_016855546 (OMIM: 606095) PREDICTED: peptidyl-pr ( 177) 544 140.9 9.5e-34
XP_016860791 (OMIM: 606093) PREDICTED: peptidyl-pr ( 272) 461 120.8 1.7e-27
NP_004783 (OMIM: 606093) peptidyl-prolyl cis-trans ( 754) 461 121.0 3.9e-27
XP_005247024 (OMIM: 606093) PREDICTED: peptidyl-pr ( 754) 461 121.0 3.9e-27
XP_005247023 (OMIM: 606093) PREDICTED: peptidyl-pr ( 754) 461 121.0 3.9e-27
XP_016861963 (OMIM: 161565) PREDICTED: NK-tumor re (1435) 457 120.2 1.3e-26
XP_006713234 (OMIM: 161565) PREDICTED: NK-tumor re (1436) 457 120.2 1.3e-26
NP_005376 (OMIM: 161565) NK-tumor recognition prot (1462) 457 120.2 1.3e-26
XP_005265230 (OMIM: 161565) PREDICTED: NK-tumor re (1463) 457 120.2 1.3e-26
XP_016855547 (OMIM: 606095) PREDICTED: peptidyl-pr ( 134) 395 104.5 6.6e-23
NP_001317439 (OMIM: 606095) peptidyl-prolyl cis-tr ( 134) 395 104.5 6.6e-23
XP_016855548 (OMIM: 606095) PREDICTED: peptidyl-pr ( 134) 395 104.5 6.6e-23
NP_057143 (OMIM: 601301) peptidyl-prolyl cis-trans ( 166) 378 100.4 1.4e-21
XP_016859845 (OMIM: 615811) PREDICTED: peptidyl-pr ( 161) 342 91.6 6e-19
XP_016859844 (OMIM: 615811) PREDICTED: peptidyl-pr ( 161) 342 91.6 6e-19
XP_011509660 (OMIM: 615811) PREDICTED: peptidyl-pr ( 161) 342 91.6 6e-19
XP_005246709 (OMIM: 615811) PREDICTED: peptidyl-pr ( 161) 342 91.6 6e-19
NP_570981 (OMIM: 615811) peptidyl-prolyl cis-trans ( 161) 342 91.6 6e-19
XP_016884195 (OMIM: 607588) PREDICTED: peptidyl-pr ( 266) 320 86.4 3.7e-17
XP_016884194 (OMIM: 607588) PREDICTED: peptidyl-pr ( 362) 320 86.4 4.8e-17
XP_011528351 (OMIM: 607588) PREDICTED: peptidyl-pr ( 438) 320 86.5 5.6e-17
XP_011528352 (OMIM: 607588) PREDICTED: peptidyl-pr ( 438) 320 86.5 5.6e-17
>>NP_001137504 (OMIM: 608608) peptidyl-prolyl cis-trans (164 aa)
initn: 1074 init1: 1074 opt: 1074 Z-score: 1426.2 bits: 270.2 E(85289): 1.1e-72
Smith-Waterman score: 1074; 97.6% identity (98.2% similar) in 164 aa overlap (1-164:1-164)
10 20 30 40 50 60
pF1KE5 MVNSVVFFDITVDGKPLGRISIKLFADKILKTAENFRALSTGEKGFRYKGSCFHRIIPGF
::::::::.:: ::::::::::::::::: ::::::::::::::::::::::::::::::
NP_001 MVNSVVFFEITRDGKPLGRISIKLFADKIPKTAENFRALSTGEKGFRYKGSCFHRIIPGF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 MCQGGDFTRHNGTGDKSIYGEKFDDENLIRKHTGSGILSMANAGPNTNGSQFFICAAKTE
::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MCQGGDFTRPNGTGDKSIYGEKFDDENLIRKHTGSGILSMANAGPNTNGSQFFICAAKTE
70 80 90 100 110 120
130 140 150 160
pF1KE5 WLDGKHVAFGKVKERVNIVEAMEHFGYRNSKTSKKITIADCGQF
::::::::::::::::::::::::::::::::::::::::::::
NP_001 WLDGKHVAFGKVKERVNIVEAMEHFGYRNSKTSKKITIADCGQF
130 140 150 160
>>NP_066953 (OMIM: 123840) peptidyl-prolyl cis-trans iso (165 aa)
initn: 984 init1: 966 opt: 966 Z-score: 1283.8 bits: 243.8 E(85289): 9.1e-65
Smith-Waterman score: 966; 86.0% identity (95.1% similar) in 164 aa overlap (1-164:1-164)
10 20 30 40 50 60
pF1KE5 MVNSVVFFDITVDGKPLGRISIKLFADKILKTAENFRALSTGEKGFRYKGSCFHRIIPGF
::: .:::::.:::.::::.:..:::::. :::::::::::::::: :::::::::::::
NP_066 MVNPTVFFDIAVDGEPLGRVSFELFADKVPKTAENFRALSTGEKGFGYKGSCFHRIIPGF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 MCQGGDFTRHNGTGDKSIYGEKFDDENLIRKHTGSGILSMANAGPNTNGSQFFICAAKTE
:::::::::::::: ::::::::.:::.: :::: ::::::::::::::::::::.::::
NP_066 MCQGGDFTRHNGTGGKSIYGEKFEDENFILKHTGPGILSMANAGPNTNGSQFFICTAKTE
70 80 90 100 110 120
130 140 150 160
pF1KE5 WLDGKHVAFGKVKERVNIVEAMEHFGYRNSKTSKKITIADCGQF
:::::::.:::::: .:::::::.:: ::.:::::::::::::.
NP_066 WLDGKHVVFGKVKEGMNIVEAMERFGSRNGKTSKKITIADCGQLE
130 140 150 160
>>NP_005720 (OMIM: 604486) peptidyl-prolyl cis-trans iso (207 aa)
initn: 767 init1: 748 opt: 778 Z-score: 1034.4 bits: 198.0 E(85289): 7e-51
Smith-Waterman score: 778; 66.7% identity (87.0% similar) in 162 aa overlap (3-164:45-206)
10 20 30
pF1KE5 MVNSVVFFDITVDGKPLGRISIKLFADKILKT
: .:..:. ..::::::. ..: :: . ::
NP_005 SVPRSVPLRLPAARACSKGSGDPSSSSSSGNPLVYLDVDANGKPLGRVVLELKADVVPKT
20 30 40 50 60 70
40 50 60 70 80 90
pF1KE5 AENFRALSTGEKGFRYKGSCFHRIIPGFMCQGGDFTRHNGTGDKSIYGEKFDDENLIRKH
::::::: :::::: :::: :::.::.::::.:::: ::::: ::::: .: :::. ::
NP_005 AENFRALCTGEKGFGYKGSTFHRVIPSFMCQAGDFTNHNGTGGKSIYGSRFPDENFTLKH
80 90 100 110 120 130
100 110 120 130 140 150
pF1KE5 TGSGILSMANAGPNTNGSQFFICAAKTEWLDGKHVAFGKVKERVNIVEAMEHFGYRNSKT
.: :.::::::::::::::::::. ::.:::::::.::.::: ...:. .: :: ....:
NP_005 VGPGVLSMANAGPNTNGSQFFICTIKTDWLDGKHVVFGHVKEGMDVVKKIESFGSKSGRT
140 150 160 170 180 190
160
pF1KE5 SKKITIADCGQF
::::.:.::::.
NP_005 SKKIVITDCGQLS
200
>>XP_016855541 (OMIM: 602435) PREDICTED: peptidyl-prolyl (217 aa)
initn: 707 init1: 689 opt: 701 Z-score: 932.6 bits: 179.3 E(85289): 3.3e-45
Smith-Waterman score: 701; 61.7% identity (80.9% similar) in 162 aa overlap (3-164:55-216)
10 20 30
pF1KE5 MVNSVVFFDITVDGKPLGRISIKLFADKILKT
: :..:: . .:: :::.. : .: . :
XP_016 TLEENKEEEGSEPPKAETQEGEPIAKKARSNPQVYMDIKIGNKPAGRIQMLLRSDVVPMT
30 40 50 60 70 80
40 50 60 70 80 90
pF1KE5 AENFRALSTGEKGFRYKGSCFHRIIPGFMCQGGDFTRHNGTGDKSIYGEKFDDENLIRKH
::::: : : :::: .::: :::::: ::::::::: ::::: :::::.::::::.: ::
XP_016 AENFRCLCTHEKGFGFKGSSFHRIIPQFMCQGGDFTNHNGTGGKSIYGKKFDDENFILKH
90 100 110 120 130 140
100 110 120 130 140 150
pF1KE5 TGSGILSMANAGPNTNGSQFFICAAKTEWLDGKHVAFGKVKERVNIVEAMEHFGYRNSKT
:: :.:::::.::::::::::. ::.:::::::.::.: : ..... .: : ...:
XP_016 TGPGLLSMANSGPNTNGSQFFLTCDKTDWLDGKHVVFGEVTEGLDVLRQIEAQGSKDGKP
150 160 170 180 190 200
160
pF1KE5 SKKITIADCGQF
..:. :::::..
XP_016 KQKVIIADCGEYV
210
>>NP_006103 (OMIM: 602435) peptidyl-prolyl cis-trans iso (301 aa)
initn: 707 init1: 689 opt: 701 Z-score: 930.5 bits: 179.3 E(85289): 4.3e-45
Smith-Waterman score: 701; 61.7% identity (80.9% similar) in 162 aa overlap (3-164:139-300)
10 20 30
pF1KE5 MVNSVVFFDITVDGKPLGRISIKLFADKILKT
: :..:: . .:: :::.. : .: . :
NP_006 TLEENKEEEGSEPPKAETQEGEPIAKKARSNPQVYMDIKIGNKPAGRIQMLLRSDVVPMT
110 120 130 140 150 160
40 50 60 70 80 90
pF1KE5 AENFRALSTGEKGFRYKGSCFHRIIPGFMCQGGDFTRHNGTGDKSIYGEKFDDENLIRKH
::::: : : :::: .::: :::::: ::::::::: ::::: :::::.::::::.: ::
NP_006 AENFRCLCTHEKGFGFKGSSFHRIIPQFMCQGGDFTNHNGTGGKSIYGKKFDDENFILKH
170 180 190 200 210 220
100 110 120 130 140 150
pF1KE5 TGSGILSMANAGPNTNGSQFFICAAKTEWLDGKHVAFGKVKERVNIVEAMEHFGYRNSKT
:: :.:::::.::::::::::. ::.:::::::.::.: : ..... .: : ...:
NP_006 TGPGLLSMANSGPNTNGSQFFLTCDKTDWLDGKHVVFGEVTEGLDVLRQIEAQGSKDGKP
230 240 250 260 270 280
160
pF1KE5 SKKITIADCGQF
..:. :::::..
NP_006 KQKVIIADCGEYV
290 300
>>XP_006710353 (OMIM: 602435) PREDICTED: peptidyl-prolyl (288 aa)
initn: 707 init1: 689 opt: 698 Z-score: 926.8 bits: 178.6 E(85289): 6.9e-45
Smith-Waterman score: 698; 62.3% identity (81.8% similar) in 159 aa overlap (6-164:129-287)
10 20 30
pF1KE5 MVNSVVFFDITVDGKPLGRISIKLFADKILKTAEN
:..:: . .:: :::.. : .: . ::::
XP_006 DDWLKKFSGKTLEENKEEEGSEPPKAETQEVYMDIKIGNKPAGRIQMLLRSDVVPMTAEN
100 110 120 130 140 150
40 50 60 70 80 90
pF1KE5 FRALSTGEKGFRYKGSCFHRIIPGFMCQGGDFTRHNGTGDKSIYGEKFDDENLIRKHTGS
:: : : :::: .::: :::::: ::::::::: ::::: :::::.::::::.: ::::
XP_006 FRCLCTHEKGFGFKGSSFHRIIPQFMCQGGDFTNHNGTGGKSIYGKKFDDENFILKHTGP
160 170 180 190 200 210
100 110 120 130 140 150
pF1KE5 GILSMANAGPNTNGSQFFICAAKTEWLDGKHVAFGKVKERVNIVEAMEHFGYRNSKTSKK
:.:::::.::::::::::. ::.:::::::.::.: : ..... .: : ...: ..:
XP_006 GLLSMANSGPNTNGSQFFLTCDKTDWLDGKHVVFGEVTEGLDVLRQIEAQGSKDGKPKQK
220 230 240 250 260 270
160
pF1KE5 ITIADCGQF
. :::::..
XP_006 VIIADCGEYV
280
>>XP_011509880 (OMIM: 601181,608033) PREDICTED: E3 SUMO- (2281 aa)
initn: 659 init1: 659 opt: 659 Z-score: 862.2 bits: 169.6 E(85289): 2.7e-41
Smith-Waterman score: 659; 59.0% identity (82.6% similar) in 161 aa overlap (3-163:2120-2280)
10 20 30
pF1KE5 MVNSVVFFDITVDGKPLGRISIKLFADKILKT
: :::::. .::.:::::...::.. . .:
XP_011 FKKTFEECQQNLMKLQKGHVSLAAELSKETNPVVFFDVCADGEPLGRITMELFSNIVPRT
2090 2100 2110 2120 2130 2140
40 50 60 70 80 90
pF1KE5 AENFRALSTGEKGFRYKGSCFHRIIPGFMCQGGDFTRHNGTGDKSIYGEKFDDENLIRKH
::::::: :::::: .:.: :::.:: :.:::::.:.:.::: .::::.::.:::. ::
XP_011 AENFRALCTGEKGFGFKNSIFHRVIPDFVCQGGDITKHDGTGGQSIYGDKFEDENFDVKH
2150 2160 2170 2180 2190 2200
100 110 120 130 140 150
pF1KE5 TGSGILSMANAGPNTNGSQFFICAAKTEWLDGKHVAFGKVKERVNIVEAMEHFGYRNSKT
:: :.::::: : :::.::: : :.: :: :::.:: ::. .. :. .: :: ....
XP_011 TGPGLLSMANQGQNTNNSQFVITLKKAEHLDFKHVVFGFVKDGMDTVKKIESFGSPKGSV
2210 2220 2230 2240 2250 2260
160
pF1KE5 SKKITIADCGQF
..:::..:::
XP_011 CRRITITECGQI
2270 2280
>>XP_005264064 (OMIM: 601181,608033) PREDICTED: E3 SUMO- (2282 aa)
initn: 659 init1: 659 opt: 659 Z-score: 862.2 bits: 169.6 E(85289): 2.7e-41
Smith-Waterman score: 659; 59.0% identity (82.6% similar) in 161 aa overlap (3-163:2121-2281)
10 20 30
pF1KE5 MVNSVVFFDITVDGKPLGRISIKLFADKILKT
: :::::. .::.:::::...::.. . .:
XP_005 FKKTFEECQQNLMKLQKGHVSLAAELSKETNPVVFFDVCADGEPLGRITMELFSNIVPRT
2100 2110 2120 2130 2140 2150
40 50 60 70 80 90
pF1KE5 AENFRALSTGEKGFRYKGSCFHRIIPGFMCQGGDFTRHNGTGDKSIYGEKFDDENLIRKH
::::::: :::::: .:.: :::.:: :.:::::.:.:.::: .::::.::.:::. ::
XP_005 AENFRALCTGEKGFGFKNSIFHRVIPDFVCQGGDITKHDGTGGQSIYGDKFEDENFDVKH
2160 2170 2180 2190 2200 2210
100 110 120 130 140 150
pF1KE5 TGSGILSMANAGPNTNGSQFFICAAKTEWLDGKHVAFGKVKERVNIVEAMEHFGYRNSKT
:: :.::::: : :::.::: : :.: :: :::.:: ::. .. :. .: :: ....
XP_005 TGPGLLSMANQGQNTNNSQFVITLKKAEHLDFKHVVFGFVKDGMDTVKKIESFGSPKGSV
2220 2230 2240 2250 2260 2270
160
pF1KE5 SKKITIADCGQF
..:::..:::
XP_005 CRRITITECGQI
2280
>>XP_011509878 (OMIM: 601181,608033) PREDICTED: E3 SUMO- (3199 aa)
initn: 659 init1: 659 opt: 659 Z-score: 860.1 bits: 169.7 E(85289): 3.6e-41
Smith-Waterman score: 659; 59.0% identity (82.6% similar) in 161 aa overlap (3-163:3038-3198)
10 20 30
pF1KE5 MVNSVVFFDITVDGKPLGRISIKLFADKILKT
: :::::. .::.:::::...::.. . .:
XP_011 FKKTFEECQQNLMKLQKGHVSLAAELSKETNPVVFFDVCADGEPLGRITMELFSNIVPRT
3010 3020 3030 3040 3050 3060
40 50 60 70 80 90
pF1KE5 AENFRALSTGEKGFRYKGSCFHRIIPGFMCQGGDFTRHNGTGDKSIYGEKFDDENLIRKH
::::::: :::::: .:.: :::.:: :.:::::.:.:.::: .::::.::.:::. ::
XP_011 AENFRALCTGEKGFGFKNSIFHRVIPDFVCQGGDITKHDGTGGQSIYGDKFEDENFDVKH
3070 3080 3090 3100 3110 3120
100 110 120 130 140 150
pF1KE5 TGSGILSMANAGPNTNGSQFFICAAKTEWLDGKHVAFGKVKERVNIVEAMEHFGYRNSKT
:: :.::::: : :::.::: : :.: :: :::.:: ::. .. :. .: :: ....
XP_011 TGPGLLSMANQGQNTNNSQFVITLKKAEHLDFKHVVFGFVKDGMDTVKKIESFGSPKGSV
3130 3140 3150 3160 3170 3180
160
pF1KE5 SKKITIADCGQF
..:::..:::
XP_011 CRRITITECGQI
3190
>>NP_006258 (OMIM: 601181,608033) E3 SUMO-protein ligase (3224 aa)
initn: 659 init1: 659 opt: 659 Z-score: 860.0 bits: 169.7 E(85289): 3.6e-41
Smith-Waterman score: 659; 59.0% identity (82.6% similar) in 161 aa overlap (3-163:3063-3223)
10 20 30
pF1KE5 MVNSVVFFDITVDGKPLGRISIKLFADKILKT
: :::::. .::.:::::...::.. . .:
NP_006 FKKTFEECQQNLMKLQKGHVSLAAELSKETNPVVFFDVCADGEPLGRITMELFSNIVPRT
3040 3050 3060 3070 3080 3090
40 50 60 70 80 90
pF1KE5 AENFRALSTGEKGFRYKGSCFHRIIPGFMCQGGDFTRHNGTGDKSIYGEKFDDENLIRKH
::::::: :::::: .:.: :::.:: :.:::::.:.:.::: .::::.::.:::. ::
NP_006 AENFRALCTGEKGFGFKNSIFHRVIPDFVCQGGDITKHDGTGGQSIYGDKFEDENFDVKH
3100 3110 3120 3130 3140 3150
100 110 120 130 140 150
pF1KE5 TGSGILSMANAGPNTNGSQFFICAAKTEWLDGKHVAFGKVKERVNIVEAMEHFGYRNSKT
:: :.::::: : :::.::: : :.: :: :::.:: ::. .. :. .: :: ....
NP_006 TGPGLLSMANQGQNTNNSQFVITLKKAEHLDFKHVVFGFVKDGMDTVKKIESFGSPKGSV
3160 3170 3180 3190 3200 3210
160
pF1KE5 SKKITIADCGQF
..:::..:::
NP_006 CRRITITECGQI
3220
164 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 07:19:26 2016 done: Tue Nov 8 07:19:27 2016
Total Scan time: 4.980 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]