Result of FASTA (omim) for
pFN21AE5115
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5115, 106 aa
1>>>pF1KE5115 106 - 106 aa - 106 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.7848+/-0.000284; mu= 12.6301+/- 0.018
mean_var=57.3758+/-11.516, 0's: 0 Z-trim(117.8): 21 B-trim: 124 in 1/53
Lambda= 0.169321
statistics sampled from 30072 (30093) to 30072 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.747), E-opt: 0.2 (0.353), width: 16
Scan time: 4.510
The best scores are: opt bits E(85289)
NP_001230587 (OMIM: 600443) glutaredoxin-1 [Homo s ( 106) 707 180.0 6.4e-46
NP_001112362 (OMIM: 600443) glutaredoxin-1 [Homo s ( 106) 707 180.0 6.4e-46
NP_002055 (OMIM: 600443) glutaredoxin-1 [Homo sapi ( 106) 707 180.0 6.4e-46
NP_001230588 (OMIM: 600443) glutaredoxin-1 [Homo s ( 106) 707 180.0 6.4e-46
NP_001306220 (OMIM: 606820) glutaredoxin 2 isoform ( 124) 203 56.9 8.4e-09
XP_016856886 (OMIM: 606820) PREDICTED: glutaredoxi ( 124) 203 56.9 8.4e-09
NP_001230328 (OMIM: 606820) glutaredoxin 2 isoform ( 124) 203 56.9 8.4e-09
NP_932066 (OMIM: 606820) glutaredoxin 2 isoform 2 ( 164) 203 57.0 1.1e-08
NP_057150 (OMIM: 606820) glutaredoxin 2 isoform 1 ( 165) 203 57.0 1.1e-08
NP_001166984 (OMIM: 606235) thioredoxin reductase ( 607) 194 55.1 1.4e-07
NP_443115 (OMIM: 606235) thioredoxin reductase 3 i ( 643) 194 55.1 1.5e-07
NP_057501 (OMIM: 205950,609588,616859,616860) glut ( 157) 160 46.4 1.5e-05
>>NP_001230587 (OMIM: 600443) glutaredoxin-1 [Homo sapie (106 aa)
initn: 707 init1: 707 opt: 707 Z-score: 945.4 bits: 180.0 E(85289): 6.4e-46
Smith-Waterman score: 707; 100.0% identity (100.0% similar) in 106 aa overlap (1-106:1-106)
10 20 30 40 50 60
pF1KE5 MAQEFVNCKIQPGKVVVFIKPTCPYCRRAQEILSQLPIKQGLLEFVDITATNHTNEIQDY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAQEFVNCKIQPGKVVVFIKPTCPYCRRAQEILSQLPIKQGLLEFVDITATNHTNEIQDY
10 20 30 40 50 60
70 80 90 100
pF1KE5 LQQLTGARTVPRVFIGKDCIGGCSDLVSLQQSGELLTRLKQIGALQ
::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LQQLTGARTVPRVFIGKDCIGGCSDLVSLQQSGELLTRLKQIGALQ
70 80 90 100
>>NP_001112362 (OMIM: 600443) glutaredoxin-1 [Homo sapie (106 aa)
initn: 707 init1: 707 opt: 707 Z-score: 945.4 bits: 180.0 E(85289): 6.4e-46
Smith-Waterman score: 707; 100.0% identity (100.0% similar) in 106 aa overlap (1-106:1-106)
10 20 30 40 50 60
pF1KE5 MAQEFVNCKIQPGKVVVFIKPTCPYCRRAQEILSQLPIKQGLLEFVDITATNHTNEIQDY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAQEFVNCKIQPGKVVVFIKPTCPYCRRAQEILSQLPIKQGLLEFVDITATNHTNEIQDY
10 20 30 40 50 60
70 80 90 100
pF1KE5 LQQLTGARTVPRVFIGKDCIGGCSDLVSLQQSGELLTRLKQIGALQ
::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LQQLTGARTVPRVFIGKDCIGGCSDLVSLQQSGELLTRLKQIGALQ
70 80 90 100
>>NP_002055 (OMIM: 600443) glutaredoxin-1 [Homo sapiens] (106 aa)
initn: 707 init1: 707 opt: 707 Z-score: 945.4 bits: 180.0 E(85289): 6.4e-46
Smith-Waterman score: 707; 100.0% identity (100.0% similar) in 106 aa overlap (1-106:1-106)
10 20 30 40 50 60
pF1KE5 MAQEFVNCKIQPGKVVVFIKPTCPYCRRAQEILSQLPIKQGLLEFVDITATNHTNEIQDY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MAQEFVNCKIQPGKVVVFIKPTCPYCRRAQEILSQLPIKQGLLEFVDITATNHTNEIQDY
10 20 30 40 50 60
70 80 90 100
pF1KE5 LQQLTGARTVPRVFIGKDCIGGCSDLVSLQQSGELLTRLKQIGALQ
::::::::::::::::::::::::::::::::::::::::::::::
NP_002 LQQLTGARTVPRVFIGKDCIGGCSDLVSLQQSGELLTRLKQIGALQ
70 80 90 100
>>NP_001230588 (OMIM: 600443) glutaredoxin-1 [Homo sapie (106 aa)
initn: 707 init1: 707 opt: 707 Z-score: 945.4 bits: 180.0 E(85289): 6.4e-46
Smith-Waterman score: 707; 100.0% identity (100.0% similar) in 106 aa overlap (1-106:1-106)
10 20 30 40 50 60
pF1KE5 MAQEFVNCKIQPGKVVVFIKPTCPYCRRAQEILSQLPIKQGLLEFVDITATNHTNEIQDY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAQEFVNCKIQPGKVVVFIKPTCPYCRRAQEILSQLPIKQGLLEFVDITATNHTNEIQDY
10 20 30 40 50 60
70 80 90 100
pF1KE5 LQQLTGARTVPRVFIGKDCIGGCSDLVSLQQSGELLTRLKQIGALQ
::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LQQLTGARTVPRVFIGKDCIGGCSDLVSLQQSGELLTRLKQIGALQ
70 80 90 100
>>NP_001306220 (OMIM: 606820) glutaredoxin 2 isoform 3 [ (124 aa)
initn: 196 init1: 133 opt: 203 Z-score: 279.0 bits: 56.9 E(85289): 8.4e-09
Smith-Waterman score: 203; 34.8% identity (68.5% similar) in 92 aa overlap (10-101:24-112)
10 20 30 40
pF1KE5 MAQEFVNCKIQPGKVVVFIKPTCPYCRRAQEILSQLPIKQGLLEFV
:. . ::.: : .: :: :.... .. .. ..:.
NP_001 MESNTSSSLENLATAPVNQIQETISDNCVVIFSKTSCSYCTMAKKLFHDMNVNYKVVEL-
10 20 30 40 50
50 60 70 80 90 100
pF1KE5 DITATNHTNEIQDYLQQLTGARTVPRVFIGKDCIGGCSDLVSLQQSGELLTRLKQIGALQ
:. .. :..:: : ..:: :::::.:.. ::: .: :.. :.:: ..:
NP_001 DLL--EYGNQFQDALYKMTGERTVPRIFVNGTFIGGATDTHRLHKEGKLLPLVHQCYLKK
60 70 80 90 100 110
NP_001 SKRKEFQ
120
>>XP_016856886 (OMIM: 606820) PREDICTED: glutaredoxin 2 (124 aa)
initn: 196 init1: 133 opt: 203 Z-score: 279.0 bits: 56.9 E(85289): 8.4e-09
Smith-Waterman score: 203; 34.8% identity (68.5% similar) in 92 aa overlap (10-101:24-112)
10 20 30 40
pF1KE5 MAQEFVNCKIQPGKVVVFIKPTCPYCRRAQEILSQLPIKQGLLEFV
:. . ::.: : .: :: :.... .. .. ..:.
XP_016 MESNTSSSLENLATAPVNQIQETISDNCVVIFSKTSCSYCTMAKKLFHDMNVNYKVVEL-
10 20 30 40 50
50 60 70 80 90 100
pF1KE5 DITATNHTNEIQDYLQQLTGARTVPRVFIGKDCIGGCSDLVSLQQSGELLTRLKQIGALQ
:. .. :..:: : ..:: :::::.:.. ::: .: :.. :.:: ..:
XP_016 DLL--EYGNQFQDALYKMTGERTVPRIFVNGTFIGGATDTHRLHKEGKLLPLVHQCYLKK
60 70 80 90 100 110
XP_016 SKRKEFQ
120
>>NP_001230328 (OMIM: 606820) glutaredoxin 2 isoform 3 [ (124 aa)
initn: 196 init1: 133 opt: 203 Z-score: 279.0 bits: 56.9 E(85289): 8.4e-09
Smith-Waterman score: 203; 34.8% identity (68.5% similar) in 92 aa overlap (10-101:24-112)
10 20 30 40
pF1KE5 MAQEFVNCKIQPGKVVVFIKPTCPYCRRAQEILSQLPIKQGLLEFV
:. . ::.: : .: :: :.... .. .. ..:.
NP_001 MESNTSSSLENLATAPVNQIQETISDNCVVIFSKTSCSYCTMAKKLFHDMNVNYKVVEL-
10 20 30 40 50
50 60 70 80 90 100
pF1KE5 DITATNHTNEIQDYLQQLTGARTVPRVFIGKDCIGGCSDLVSLQQSGELLTRLKQIGALQ
:. .. :..:: : ..:: :::::.:.. ::: .: :.. :.:: ..:
NP_001 DLL--EYGNQFQDALYKMTGERTVPRIFVNGTFIGGATDTHRLHKEGKLLPLVHQCYLKK
60 70 80 90 100 110
NP_001 SKRKEFQ
120
>>NP_932066 (OMIM: 606820) glutaredoxin 2 isoform 2 prec (164 aa)
initn: 196 init1: 133 opt: 203 Z-score: 277.2 bits: 57.0 E(85289): 1.1e-08
Smith-Waterman score: 203; 34.8% identity (68.5% similar) in 92 aa overlap (10-101:64-152)
10 20 30
pF1KE5 MAQEFVNCKIQPGKVVVFIKPTCPYCRRAQEILSQLPIK
:. . ::.: : .: :: :.... .. ..
NP_932 AAAAASGMESNTSSSLENLATAPVNQIQETISDNCVVIFSKTSCSYCTMAKKLFHDMNVN
40 50 60 70 80 90
40 50 60 70 80 90
pF1KE5 QGLLEFVDITATNHTNEIQDYLQQLTGARTVPRVFIGKDCIGGCSDLVSLQQSGELLTRL
..:. :. .. :..:: : ..:: :::::.:.. ::: .: :.. :.:: .
NP_932 YKVVEL-DLL--EYGNQFQDALYKMTGERTVPRIFVNGTFIGGATDTHRLHKEGKLLPLV
100 110 120 130 140 150
100
pF1KE5 KQIGALQ
.:
NP_932 HQCYLKKSKRKEFQ
160
>>NP_057150 (OMIM: 606820) glutaredoxin 2 isoform 1 [Hom (165 aa)
initn: 196 init1: 133 opt: 203 Z-score: 277.2 bits: 57.0 E(85289): 1.1e-08
Smith-Waterman score: 203; 34.8% identity (68.5% similar) in 92 aa overlap (10-101:65-153)
10 20 30
pF1KE5 MAQEFVNCKIQPGKVVVFIKPTCPYCRRAQEILSQLPIK
:. . ::.: : .: :: :.... .. ..
NP_057 TRSAARRMESNTSSSLENLATAPVNQIQETISDNCVVIFSKTSCSYCTMAKKLFHDMNVN
40 50 60 70 80 90
40 50 60 70 80 90
pF1KE5 QGLLEFVDITATNHTNEIQDYLQQLTGARTVPRVFIGKDCIGGCSDLVSLQQSGELLTRL
..:. :. .. :..:: : ..:: :::::.:.. ::: .: :.. :.:: .
NP_057 YKVVEL-DLL--EYGNQFQDALYKMTGERTVPRIFVNGTFIGGATDTHRLHKEGKLLPLV
100 110 120 130 140 150
100
pF1KE5 KQIGALQ
.:
NP_057 HQCYLKKSKRKEFQ
160
>>NP_001166984 (OMIM: 606235) thioredoxin reductase 3 is (607 aa)
initn: 203 init1: 113 opt: 194 Z-score: 257.1 bits: 55.1 E(85289): 1.4e-07
Smith-Waterman score: 194; 33.7% identity (70.7% similar) in 92 aa overlap (10-101:63-150)
10 20 30
pF1KE5 MAQEFVNCKIQPGKVVVFIKPTCPYCRRAQEILSQLPIK
:. ..::.: : ::. :..:..:.: ..
NP_001 PPGRRARLSSPGPSRSSEAREELRRHLVGLIERSRVVIFSKSYCPHSTRVKELFSSLGVE
40 50 60 70 80 90
40 50 60 70 80 90
pF1KE5 QGLLEFVDITATNHTNEIQDYLQQLTGARTVPRVFIGKDCIGGCSDLVSLQQSGELLTRL
..::. .. . ..:. :...:. .::: .:..: .:::.. . ::: :: .:
NP_001 CNVLELDQV---DDGARVQEVLSEITNQKTVPNIFVNKVHVGGCDQTFQAYQSG-LLQKL
100 110 120 130 140
100
pF1KE5 KQIGALQ
:
NP_001 LQEDLAYDYDLIIIGGGSGGLSCAKEAAILGKKVMVLDFVVPSPQGTSWGLGGTCVNVGC
150 160 170 180 190 200
106 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 21:29:09 2016 done: Mon Nov 7 21:29:09 2016
Total Scan time: 4.510 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]