Result of FASTA (omim) for
pFN21AE5074
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5074, 176 aa
1>>>pF1KE5074 176 - 176 aa - 176 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.5341+/-0.000246; mu= 13.1237+/- 0.016
mean_var=87.1259+/-17.307, 0's: 0 Z-trim(122.9): 112 B-trim: 0 in 0/59
Lambda= 0.137404
statistics sampled from 41620 (41746) to 41620 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.819), E-opt: 0.2 (0.489), width: 16
Scan time: 5.710
The best scores are: opt bits E(85289)
XP_011522536 (OMIM: 606618) PREDICTED: dual specif ( 198) 321 72.2 5.5e-13
XP_005257034 (OMIM: 606618) PREDICTED: dual specif ( 198) 321 72.2 5.5e-13
NP_008957 (OMIM: 606618) dual specificity protein ( 198) 321 72.2 5.5e-13
NP_689724 (OMIM: 611446) dual specificity protein ( 188) 309 69.8 2.8e-12
XP_011528222 (OMIM: 611446) PREDICTED: dual specif ( 188) 309 69.8 2.8e-12
XP_011528223 (OMIM: 611446) PREDICTED: dual specif ( 188) 309 69.8 2.8e-12
XP_016884117 (OMIM: 611446) PREDICTED: dual specif ( 188) 309 69.8 2.8e-12
NP_001291723 (OMIM: 611446) dual specificity prote ( 188) 309 69.8 2.8e-12
NP_001291724 (OMIM: 611446) dual specificity prote ( 188) 309 69.8 2.8e-12
XP_006724211 (OMIM: 611446) PREDICTED: dual specif ( 188) 309 69.8 2.8e-12
XP_016884116 (OMIM: 611446) PREDICTED: dual specif ( 188) 309 69.8 2.8e-12
XP_005261425 (OMIM: 611446) PREDICTED: dual specif ( 188) 309 69.8 2.8e-12
NP_009171 (OMIM: 604835) dual specificity protein ( 340) 306 69.4 6.6e-12
XP_011518235 (OMIM: 602038) PREDICTED: dual specif ( 625) 308 70.0 7.9e-12
NP_004411 (OMIM: 602038) dual specificity protein ( 625) 308 70.0 7.9e-12
XP_011518234 (OMIM: 602038) PREDICTED: dual specif ( 625) 308 70.0 7.9e-12
NP_542178 (OMIM: 616776) dual specificity protein ( 235) 298 67.7 1.5e-11
XP_016883146 (OMIM: 616776) PREDICTED: dual specif ( 298) 298 67.8 1.8e-11
XP_016883145 (OMIM: 616776) PREDICTED: dual specif ( 311) 298 67.8 1.8e-11
XP_016873431 (OMIM: 606780) PREDICTED: protein pho ( 559) 301 68.6 1.9e-11
XP_016880743 (OMIM: 606779) PREDICTED: protein pho ( 480) 300 68.3 1.9e-11
XP_016883143 (OMIM: 616776) PREDICTED: dual specif ( 335) 298 67.8 2e-11
NP_004408 (OMIM: 600714) dual specificity protein ( 367) 298 67.8 2.1e-11
NP_060327 (OMIM: 606780) protein phosphatase Sling ( 659) 301 68.6 2.2e-11
XP_016880742 (OMIM: 606779) PREDICTED: protein pho ( 529) 299 68.2 2.4e-11
NP_085143 (OMIM: 607175) dual specificity protein ( 665) 299 68.2 2.9e-11
XP_011519159 (OMIM: 607175) PREDICTED: dual specif ( 665) 299 68.2 2.9e-11
XP_006719218 (OMIM: 607175) PREDICTED: dual specif ( 665) 299 68.2 2.9e-11
XP_011519158 (OMIM: 607175) PREDICTED: dual specif ( 665) 299 68.2 2.9e-11
NP_001307407 (OMIM: 616776) dual specificity prote ( 232) 292 66.5 3.4e-11
NP_004410 (OMIM: 603069) dual specificity protein ( 384) 294 67.1 3.8e-11
NP_001307408 (OMIM: 616776) dual specificity prote ( 295) 292 66.6 4e-11
XP_016883144 (OMIM: 616776) PREDICTED: dual specif ( 332) 292 66.6 4.4e-11
XP_016880741 (OMIM: 606779) PREDICTED: protein pho (1328) 299 68.5 4.8e-11
XP_011523708 (OMIM: 606779) PREDICTED: protein pho (1347) 299 68.5 4.9e-11
XP_011523709 (OMIM: 606779) PREDICTED: protein pho (1347) 299 68.5 4.9e-11
XP_011523707 (OMIM: 606779) PREDICTED: protein pho (1394) 299 68.5 5e-11
XP_006722212 (OMIM: 606779) PREDICTED: protein pho (1401) 299 68.5 5e-11
XP_011523706 (OMIM: 606779) PREDICTED: protein pho (1405) 299 68.5 5.1e-11
NP_203747 (OMIM: 606779) protein phosphatase Sling (1423) 299 68.5 5.1e-11
XP_011523704 (OMIM: 606779) PREDICTED: protein pho (1430) 299 68.5 5.1e-11
XP_005258116 (OMIM: 606779) PREDICTED: protein pho (1430) 299 68.5 5.1e-11
XP_016880740 (OMIM: 606779) PREDICTED: protein pho (1449) 299 68.5 5.2e-11
NP_001269058 (OMIM: 606779) protein phosphatase Sl (1450) 299 68.5 5.2e-11
XP_005258115 (OMIM: 606779) PREDICTED: protein pho (1450) 299 68.5 5.2e-11
NP_001154802 (OMIM: 606778) protein phosphatase Sl ( 692) 289 66.3 1.2e-10
NP_001154803 (OMIM: 606778) protein phosphatase Sl ( 703) 289 66.3 1.2e-10
XP_016874981 (OMIM: 606778) PREDICTED: protein pho ( 923) 289 66.4 1.5e-10
XP_005269042 (OMIM: 606778) PREDICTED: protein pho ( 969) 289 66.4 1.5e-10
XP_011536803 (OMIM: 606778) PREDICTED: protein pho ( 969) 289 66.4 1.5e-10
>>XP_011522536 (OMIM: 606618) PREDICTED: dual specificit (198 aa)
initn: 328 init1: 307 opt: 321 Z-score: 354.1 bits: 72.2 E(85289): 5.5e-13
Smith-Waterman score: 321; 33.8% identity (63.1% similar) in 157 aa overlap (19-175:27-183)
10 20 30 40 50
pF1KE5 MGPAEAGRRGAASPVPPPLVRVAPSLFLGSARAAGAEEQLARAGVTLCVNVS
..... ::::: . .:. .. : :.: ::..
XP_011 MSSRGHSTLPRTLMAPRMISEGDIGGIAQITSSLFLGRGSVASNRHLLQARGITCIVNAT
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE5 RQQPGPRAPGVAELRVPVFDDPAEDLLAHLEPTCAAMEAAVRAGGACLVYCKNGRSRSAA
. :. : ..::. : : . ... . .... : :: ::.: : ::::.
XP_011 IEIPNFNWPQFEYVKVPLADMPHAPIGLYFDTVADKIHSVSRKHGATLVHCAAGVSRSAT
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE5 VCTAYLMRHRGLSLAKAFQMVKSARPVAEPNPGFWSQLQKYEEALQAQSCLQGEPPALGL
.: ::::. ... : .:.. ::. ::: .:: ::: :: ::. : ..: .. :.
XP_011 LCIAYLMKFHNVCLLEAYNWVKARRPVIRPNVGFWRQLIDYERQLFGKSTVKMVQTPYGI
130 140 150 160 170 180
pF1KE5 GPEA
:.
XP_011 VPDVYEKESRHLMPYWGI
190
>>XP_005257034 (OMIM: 606618) PREDICTED: dual specificit (198 aa)
initn: 328 init1: 307 opt: 321 Z-score: 354.1 bits: 72.2 E(85289): 5.5e-13
Smith-Waterman score: 321; 33.8% identity (63.1% similar) in 157 aa overlap (19-175:27-183)
10 20 30 40 50
pF1KE5 MGPAEAGRRGAASPVPPPLVRVAPSLFLGSARAAGAEEQLARAGVTLCVNVS
..... ::::: . .:. .. : :.: ::..
XP_005 MSSRGHSTLPRTLMAPRMISEGDIGGIAQITSSLFLGRGSVASNRHLLQARGITCIVNAT
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE5 RQQPGPRAPGVAELRVPVFDDPAEDLLAHLEPTCAAMEAAVRAGGACLVYCKNGRSRSAA
. :. : ..::. : : . ... . .... : :: ::.: : ::::.
XP_005 IEIPNFNWPQFEYVKVPLADMPHAPIGLYFDTVADKIHSVSRKHGATLVHCAAGVSRSAT
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE5 VCTAYLMRHRGLSLAKAFQMVKSARPVAEPNPGFWSQLQKYEEALQAQSCLQGEPPALGL
.: ::::. ... : .:.. ::. ::: .:: ::: :: ::. : ..: .. :.
XP_005 LCIAYLMKFHNVCLLEAYNWVKARRPVIRPNVGFWRQLIDYERQLFGKSTVKMVQTPYGI
130 140 150 160 170 180
pF1KE5 GPEA
:.
XP_005 VPDVYEKESRHLMPYWGI
190
>>NP_008957 (OMIM: 606618) dual specificity protein phos (198 aa)
initn: 328 init1: 307 opt: 321 Z-score: 354.1 bits: 72.2 E(85289): 5.5e-13
Smith-Waterman score: 321; 33.8% identity (63.1% similar) in 157 aa overlap (19-175:27-183)
10 20 30 40 50
pF1KE5 MGPAEAGRRGAASPVPPPLVRVAPSLFLGSARAAGAEEQLARAGVTLCVNVS
..... ::::: . .:. .. : :.: ::..
NP_008 MSSRGHSTLPRTLMAPRMISEGDIGGIAQITSSLFLGRGSVASNRHLLQARGITCIVNAT
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE5 RQQPGPRAPGVAELRVPVFDDPAEDLLAHLEPTCAAMEAAVRAGGACLVYCKNGRSRSAA
. :. : ..::. : : . ... . .... : :: ::.: : ::::.
NP_008 IEIPNFNWPQFEYVKVPLADMPHAPIGLYFDTVADKIHSVSRKHGATLVHCAAGVSRSAT
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE5 VCTAYLMRHRGLSLAKAFQMVKSARPVAEPNPGFWSQLQKYEEALQAQSCLQGEPPALGL
.: ::::. ... : .:.. ::. ::: .:: ::: :: ::. : ..: .. :.
NP_008 LCIAYLMKFHNVCLLEAYNWVKARRPVIRPNVGFWRQLIDYERQLFGKSTVKMVQTPYGI
130 140 150 160 170 180
pF1KE5 GPEA
:.
NP_008 VPDVYEKESRHLMPYWGI
190
>>NP_689724 (OMIM: 611446) dual specificity protein phos (188 aa)
initn: 289 init1: 289 opt: 309 Z-score: 341.5 bits: 69.8 E(85289): 2.8e-12
Smith-Waterman score: 309; 31.5% identity (60.5% similar) in 162 aa overlap (14-175:15-176)
10 20 30 40 50
pF1KE5 MGPAEAGRRGAASPVPPPLVRVAPSLFLGSARAAGAEEQLARAGVTLCVNVSRQQPGPR
: : ... ::..... ::. . .:. .:. .::: . .
NP_689 MTAPSCAFPVQFRQPSVSGLSQITKSLYISNGVAANNKLMLSSNQITMVINVSVEVVNTL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE5 APGVAELRVPVFDDPAEDLLAHLEPTCAAMEAAVRAGGACLVYCKNGRSRSAAVCTAYLM
. ..::: :.: : ..: .... : :..: : :::::.: ::::
NP_689 YEDIQYMQVPVADSPNSRLCDFFDPIADHIHSVEMKQGRTLLHCAAGVSRSAALCLAYLM
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE5 RHRGLSLAKAFQMVKSARPVAEPNPGFWSQLQKYEEALQAQSCLQGEPPALGLGPEA
.....:: : .:: ::. .:: ::: :: .:: : ... .. .:. :.
NP_689 KYHAMSLLDAHTWTKSCRPIIRPNSGFWEQLIHYEFQLFGKNTVHMVSSPVGMIPDIYEK
130 140 150 160 170 180
NP_689 EVRLMIPL
>>XP_011528222 (OMIM: 611446) PREDICTED: dual specificit (188 aa)
initn: 289 init1: 289 opt: 309 Z-score: 341.5 bits: 69.8 E(85289): 2.8e-12
Smith-Waterman score: 309; 31.5% identity (60.5% similar) in 162 aa overlap (14-175:15-176)
10 20 30 40 50
pF1KE5 MGPAEAGRRGAASPVPPPLVRVAPSLFLGSARAAGAEEQLARAGVTLCVNVSRQQPGPR
: : ... ::..... ::. . .:. .:. .::: . .
XP_011 MTAPSCAFPVQFRQPSVSGLSQITKSLYISNGVAANNKLMLSSNQITMVINVSVEVVNTL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE5 APGVAELRVPVFDDPAEDLLAHLEPTCAAMEAAVRAGGACLVYCKNGRSRSAAVCTAYLM
. ..::: :.: : ..: .... : :..: : :::::.: ::::
XP_011 YEDIQYMQVPVADSPNSRLCDFFDPIADHIHSVEMKQGRTLLHCAAGVSRSAALCLAYLM
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE5 RHRGLSLAKAFQMVKSARPVAEPNPGFWSQLQKYEEALQAQSCLQGEPPALGLGPEA
.....:: : .:: ::. .:: ::: :: .:: : ... .. .:. :.
XP_011 KYHAMSLLDAHTWTKSCRPIIRPNSGFWEQLIHYEFQLFGKNTVHMVSSPVGMIPDIYEK
130 140 150 160 170 180
XP_011 EVRLMIPL
>>XP_011528223 (OMIM: 611446) PREDICTED: dual specificit (188 aa)
initn: 289 init1: 289 opt: 309 Z-score: 341.5 bits: 69.8 E(85289): 2.8e-12
Smith-Waterman score: 309; 31.5% identity (60.5% similar) in 162 aa overlap (14-175:15-176)
10 20 30 40 50
pF1KE5 MGPAEAGRRGAASPVPPPLVRVAPSLFLGSARAAGAEEQLARAGVTLCVNVSRQQPGPR
: : ... ::..... ::. . .:. .:. .::: . .
XP_011 MTAPSCAFPVQFRQPSVSGLSQITKSLYISNGVAANNKLMLSSNQITMVINVSVEVVNTL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE5 APGVAELRVPVFDDPAEDLLAHLEPTCAAMEAAVRAGGACLVYCKNGRSRSAAVCTAYLM
. ..::: :.: : ..: .... : :..: : :::::.: ::::
XP_011 YEDIQYMQVPVADSPNSRLCDFFDPIADHIHSVEMKQGRTLLHCAAGVSRSAALCLAYLM
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE5 RHRGLSLAKAFQMVKSARPVAEPNPGFWSQLQKYEEALQAQSCLQGEPPALGLGPEA
.....:: : .:: ::. .:: ::: :: .:: : ... .. .:. :.
XP_011 KYHAMSLLDAHTWTKSCRPIIRPNSGFWEQLIHYEFQLFGKNTVHMVSSPVGMIPDIYEK
130 140 150 160 170 180
XP_011 EVRLMIPL
>>XP_016884117 (OMIM: 611446) PREDICTED: dual specificit (188 aa)
initn: 289 init1: 289 opt: 309 Z-score: 341.5 bits: 69.8 E(85289): 2.8e-12
Smith-Waterman score: 309; 31.5% identity (60.5% similar) in 162 aa overlap (14-175:15-176)
10 20 30 40 50
pF1KE5 MGPAEAGRRGAASPVPPPLVRVAPSLFLGSARAAGAEEQLARAGVTLCVNVSRQQPGPR
: : ... ::..... ::. . .:. .:. .::: . .
XP_016 MTAPSCAFPVQFRQPSVSGLSQITKSLYISNGVAANNKLMLSSNQITMVINVSVEVVNTL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE5 APGVAELRVPVFDDPAEDLLAHLEPTCAAMEAAVRAGGACLVYCKNGRSRSAAVCTAYLM
. ..::: :.: : ..: .... : :..: : :::::.: ::::
XP_016 YEDIQYMQVPVADSPNSRLCDFFDPIADHIHSVEMKQGRTLLHCAAGVSRSAALCLAYLM
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE5 RHRGLSLAKAFQMVKSARPVAEPNPGFWSQLQKYEEALQAQSCLQGEPPALGLGPEA
.....:: : .:: ::. .:: ::: :: .:: : ... .. .:. :.
XP_016 KYHAMSLLDAHTWTKSCRPIIRPNSGFWEQLIHYEFQLFGKNTVHMVSSPVGMIPDIYEK
130 140 150 160 170 180
XP_016 EVRLMIPL
>>NP_001291723 (OMIM: 611446) dual specificity protein p (188 aa)
initn: 289 init1: 289 opt: 309 Z-score: 341.5 bits: 69.8 E(85289): 2.8e-12
Smith-Waterman score: 309; 31.5% identity (60.5% similar) in 162 aa overlap (14-175:15-176)
10 20 30 40 50
pF1KE5 MGPAEAGRRGAASPVPPPLVRVAPSLFLGSARAAGAEEQLARAGVTLCVNVSRQQPGPR
: : ... ::..... ::. . .:. .:. .::: . .
NP_001 MTAPSCAFPVQFRQPSVSGLSQITKSLYISNGVAANNKLMLSSNQITMVINVSVEVVNTL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE5 APGVAELRVPVFDDPAEDLLAHLEPTCAAMEAAVRAGGACLVYCKNGRSRSAAVCTAYLM
. ..::: :.: : ..: .... : :..: : :::::.: ::::
NP_001 YEDIQYMQVPVADSPNSRLCDFFDPIADHIHSVEMKQGRTLLHCAAGVSRSAALCLAYLM
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE5 RHRGLSLAKAFQMVKSARPVAEPNPGFWSQLQKYEEALQAQSCLQGEPPALGLGPEA
.....:: : .:: ::. .:: ::: :: .:: : ... .. .:. :.
NP_001 KYHAMSLLDAHTWTKSCRPIIRPNSGFWEQLIHYEFQLFGKNTVHMVSSPVGMIPDIYEK
130 140 150 160 170 180
NP_001 EVRLMIPL
>>NP_001291724 (OMIM: 611446) dual specificity protein p (188 aa)
initn: 289 init1: 289 opt: 309 Z-score: 341.5 bits: 69.8 E(85289): 2.8e-12
Smith-Waterman score: 309; 31.5% identity (60.5% similar) in 162 aa overlap (14-175:15-176)
10 20 30 40 50
pF1KE5 MGPAEAGRRGAASPVPPPLVRVAPSLFLGSARAAGAEEQLARAGVTLCVNVSRQQPGPR
: : ... ::..... ::. . .:. .:. .::: . .
NP_001 MTAPSCAFPVQFRQPSVSGLSQITKSLYISNGVAANNKLMLSSNQITMVINVSVEVVNTL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE5 APGVAELRVPVFDDPAEDLLAHLEPTCAAMEAAVRAGGACLVYCKNGRSRSAAVCTAYLM
. ..::: :.: : ..: .... : :..: : :::::.: ::::
NP_001 YEDIQYMQVPVADSPNSRLCDFFDPIADHIHSVEMKQGRTLLHCAAGVSRSAALCLAYLM
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE5 RHRGLSLAKAFQMVKSARPVAEPNPGFWSQLQKYEEALQAQSCLQGEPPALGLGPEA
.....:: : .:: ::. .:: ::: :: .:: : ... .. .:. :.
NP_001 KYHAMSLLDAHTWTKSCRPIIRPNSGFWEQLIHYEFQLFGKNTVHMVSSPVGMIPDIYEK
130 140 150 160 170 180
NP_001 EVRLMIPL
>>XP_006724211 (OMIM: 611446) PREDICTED: dual specificit (188 aa)
initn: 289 init1: 289 opt: 309 Z-score: 341.5 bits: 69.8 E(85289): 2.8e-12
Smith-Waterman score: 309; 31.5% identity (60.5% similar) in 162 aa overlap (14-175:15-176)
10 20 30 40 50
pF1KE5 MGPAEAGRRGAASPVPPPLVRVAPSLFLGSARAAGAEEQLARAGVTLCVNVSRQQPGPR
: : ... ::..... ::. . .:. .:. .::: . .
XP_006 MTAPSCAFPVQFRQPSVSGLSQITKSLYISNGVAANNKLMLSSNQITMVINVSVEVVNTL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE5 APGVAELRVPVFDDPAEDLLAHLEPTCAAMEAAVRAGGACLVYCKNGRSRSAAVCTAYLM
. ..::: :.: : ..: .... : :..: : :::::.: ::::
XP_006 YEDIQYMQVPVADSPNSRLCDFFDPIADHIHSVEMKQGRTLLHCAAGVSRSAALCLAYLM
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE5 RHRGLSLAKAFQMVKSARPVAEPNPGFWSQLQKYEEALQAQSCLQGEPPALGLGPEA
.....:: : .:: ::. .:: ::: :: .:: : ... .. .:. :.
XP_006 KYHAMSLLDAHTWTKSCRPIIRPNSGFWEQLIHYEFQLFGKNTVHMVSSPVGMIPDIYEK
130 140 150 160 170 180
XP_006 EVRLMIPL
176 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 04:47:10 2016 done: Tue Nov 8 04:47:11 2016
Total Scan time: 5.710 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]