Result of FASTA (ccds) for
pFN21AE5074
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5074, 176 aa
1>>>pF1KE5074 176 - 176 aa - 176 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.5039+/-0.000554; mu= 13.4752+/- 0.034
mean_var=84.5066+/-16.663, 0's: 0 Z-trim(115.6): 43 B-trim: 26 in 1/51
Lambda= 0.139518
statistics sampled from 16088 (16136) to 16088 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.823), E-opt: 0.2 (0.496), width: 16
Scan time: 1.860
The best scores are: opt bits E(32554)
CCDS33418.1 DUSP28 gene_id:285193|Hs108|chr2 ( 176) 1192 248.3 1.9e-66
CCDS11320.1 DUSP14 gene_id:11072|Hs108|chr17 ( 198) 321 73.0 1.2e-13
CCDS13883.1 DUSP18 gene_id:150290|Hs108|chr22 ( 188) 309 70.5 6.3e-13
CCDS1234.1 DUSP12 gene_id:11266|Hs108|chr1 ( 340) 306 70.1 1.5e-12
CCDS7724.1 DUSP8 gene_id:1850|Hs108|chr11 ( 625) 308 70.7 1.8e-12
CCDS13193.1 DUSP15 gene_id:128853|Hs108|chr20 ( 235) 298 68.4 3.5e-12
CCDS4380.1 DUSP1 gene_id:1843|Hs108|chr5 ( 367) 298 68.6 4.9e-12
CCDS8157.1 SSH3 gene_id:54961|Hs108|chr11 ( 659) 301 69.4 5e-12
CCDS8650.1 DUSP16 gene_id:80824|Hs108|chr12 ( 665) 299 69.0 6.7e-12
CCDS82607.1 DUSP15 gene_id:128853|Hs108|chr20 ( 232) 292 67.2 7.9e-12
CCDS7566.1 DUSP5 gene_id:1847|Hs108|chr10 ( 384) 294 67.8 8.8e-12
CCDS82606.1 DUSP15 gene_id:128853|Hs108|chr20 ( 295) 292 67.3 9.5e-12
CCDS11253.1 SSH2 gene_id:85464|Hs108|chr17 (1423) 299 69.2 1.2e-11
CCDS74024.1 SSH2 gene_id:85464|Hs108|chr17 (1450) 299 69.2 1.2e-11
CCDS55882.1 SSH1 gene_id:54434|Hs108|chr12 ( 692) 289 67.0 2.8e-11
CCDS53825.1 SSH1 gene_id:54434|Hs108|chr12 ( 703) 289 67.0 2.8e-11
CCDS9121.1 SSH1 gene_id:54434|Hs108|chr12 (1049) 289 67.1 3.8e-11
CCDS6073.1 DUSP4 gene_id:1846|Hs108|chr8 ( 303) 279 64.7 5.9e-11
CCDS6072.1 DUSP4 gene_id:1846|Hs108|chr8 ( 394) 279 64.8 7.3e-11
CCDS14264.1 DUSP21 gene_id:63904|Hs108|chrX ( 190) 274 63.5 8.3e-11
>>CCDS33418.1 DUSP28 gene_id:285193|Hs108|chr2 (176 aa)
initn: 1192 init1: 1192 opt: 1192 Z-score: 1306.5 bits: 248.3 E(32554): 1.9e-66
Smith-Waterman score: 1192; 100.0% identity (100.0% similar) in 176 aa overlap (1-176:1-176)
10 20 30 40 50 60
pF1KE5 MGPAEAGRRGAASPVPPPLVRVAPSLFLGSARAAGAEEQLARAGVTLCVNVSRQQPGPRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 MGPAEAGRRGAASPVPPPLVRVAPSLFLGSARAAGAEEQLARAGVTLCVNVSRQQPGPRA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 PGVAELRVPVFDDPAEDLLAHLEPTCAAMEAAVRAGGACLVYCKNGRSRSAAVCTAYLMR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 PGVAELRVPVFDDPAEDLLAHLEPTCAAMEAAVRAGGACLVYCKNGRSRSAAVCTAYLMR
70 80 90 100 110 120
130 140 150 160 170
pF1KE5 HRGLSLAKAFQMVKSARPVAEPNPGFWSQLQKYEEALQAQSCLQGEPPALGLGPEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 HRGLSLAKAFQMVKSARPVAEPNPGFWSQLQKYEEALQAQSCLQGEPPALGLGPEA
130 140 150 160 170
>>CCDS11320.1 DUSP14 gene_id:11072|Hs108|chr17 (198 aa)
initn: 328 init1: 307 opt: 321 Z-score: 358.3 bits: 73.0 E(32554): 1.2e-13
Smith-Waterman score: 321; 33.8% identity (63.1% similar) in 157 aa overlap (19-175:27-183)
10 20 30 40 50
pF1KE5 MGPAEAGRRGAASPVPPPLVRVAPSLFLGSARAAGAEEQLARAGVTLCVNVS
..... ::::: . .:. .. : :.: ::..
CCDS11 MSSRGHSTLPRTLMAPRMISEGDIGGIAQITSSLFLGRGSVASNRHLLQARGITCIVNAT
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE5 RQQPGPRAPGVAELRVPVFDDPAEDLLAHLEPTCAAMEAAVRAGGACLVYCKNGRSRSAA
. :. : ..::. : : . ... . .... : :: ::.: : ::::.
CCDS11 IEIPNFNWPQFEYVKVPLADMPHAPIGLYFDTVADKIHSVSRKHGATLVHCAAGVSRSAT
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE5 VCTAYLMRHRGLSLAKAFQMVKSARPVAEPNPGFWSQLQKYEEALQAQSCLQGEPPALGL
.: ::::. ... : .:.. ::. ::: .:: ::: :: ::. : ..: .. :.
CCDS11 LCIAYLMKFHNVCLLEAYNWVKARRPVIRPNVGFWRQLIDYERQLFGKSTVKMVQTPYGI
130 140 150 160 170 180
pF1KE5 GPEA
:.
CCDS11 VPDVYEKESRHLMPYWGI
190
>>CCDS13883.1 DUSP18 gene_id:150290|Hs108|chr22 (188 aa)
initn: 289 init1: 289 opt: 309 Z-score: 345.6 bits: 70.5 E(32554): 6.3e-13
Smith-Waterman score: 309; 31.5% identity (60.5% similar) in 162 aa overlap (14-175:15-176)
10 20 30 40 50
pF1KE5 MGPAEAGRRGAASPVPPPLVRVAPSLFLGSARAAGAEEQLARAGVTLCVNVSRQQPGPR
: : ... ::..... ::. . .:. .:. .::: . .
CCDS13 MTAPSCAFPVQFRQPSVSGLSQITKSLYISNGVAANNKLMLSSNQITMVINVSVEVVNTL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE5 APGVAELRVPVFDDPAEDLLAHLEPTCAAMEAAVRAGGACLVYCKNGRSRSAAVCTAYLM
. ..::: :.: : ..: .... : :..: : :::::.: ::::
CCDS13 YEDIQYMQVPVADSPNSRLCDFFDPIADHIHSVEMKQGRTLLHCAAGVSRSAALCLAYLM
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE5 RHRGLSLAKAFQMVKSARPVAEPNPGFWSQLQKYEEALQAQSCLQGEPPALGLGPEA
.....:: : .:: ::. .:: ::: :: .:: : ... .. .:. :.
CCDS13 KYHAMSLLDAHTWTKSCRPIIRPNSGFWEQLIHYEFQLFGKNTVHMVSSPVGMIPDIYEK
130 140 150 160 170 180
CCDS13 EVRLMIPL
>>CCDS1234.1 DUSP12 gene_id:11266|Hs108|chr1 (340 aa)
initn: 225 init1: 225 opt: 306 Z-score: 338.8 bits: 70.1 E(32554): 1.5e-12
Smith-Waterman score: 306; 39.0% identity (70.2% similar) in 141 aa overlap (19-154:27-166)
10 20 30 40 50
pF1KE5 MGPAEAGRRGAASPVPPPLVRVAPSLFLGSARAAGAEEQLARAGVTLCVNVS
...: :.:..:.: :.. ..: .::.: ..:.
CCDS12 MLEAPGPSDGCELSNPSASRVSCAGQMLEVQPGLYFGGAAAVAEPDHLREAGITAVLTVD
10 20 30 40 50 60
60 70 80 90 100
pF1KE5 RQQPGPRA-PGVAELR---VPVFDDPAEDLLAHLEPTCAAMEAAVRAGG-ACLVYCKNGR
..:. .: ::: .: ::..: : :::.::. :.:. . .:: : : ::.:. :
CCDS12 SEEPSFKAGPGVEDLWRLFVPALDKPETDLLSHLD-RCVAFIGQARAEGRAVLVHCHAGV
70 80 90 100 110
110 120 130 140 150 160
pF1KE5 SRSAAVCTAYLMRHRGLSLAKAFQMVKSARPVAEPNPGFWSQLQKYEEALQAQSCLQGEP
:::.:. ::.::. : . ::.. .. .: :. : :: ::. :.
CCDS12 SRSVAIITAFLMKTDQLPFEKAYEKLQILKPEAKMNEGFEWQLKLYQAMGYEVDTSSAIY
120 130 140 150 160 170
170
pF1KE5 PALGLGPEA
CCDS12 KQYRLQKVTEKYPELQNLPQELFAVDPTTVSQGLKDEVLYKCRKCRRSLFRSSSILDHRE
180 190 200 210 220 230
>>CCDS7724.1 DUSP8 gene_id:1850|Hs108|chr11 (625 aa)
initn: 235 init1: 235 opt: 308 Z-score: 337.3 bits: 70.7 E(32554): 1.8e-12
Smith-Waterman score: 308; 33.5% identity (62.2% similar) in 164 aa overlap (14-175:155-318)
10 20 30 40
pF1KE5 MGPAEAGRRGAASPVPP-PLVRVAPSLFLGSARAAGAEEQLAR
::: :.:. : :.::: . . .. ...
CCDS77 GFATFSSCFPGLCEGKPAALLPMSLSQPCLPVPSVGLTRILPHLYLGSQKDVLNKDLMTQ
130 140 150 160 170 180
50 60 70 80 90 100
pF1KE5 AGVTLCVNVSRQQPGPRAPGVAE-LRVPVFDDPAEDLLAHLEPTCAAMEAAVRAGGACLV
:.. .:.: . : : .. .:::. :. : :: :. . .. : .. .:
CCDS77 NGISYVLNASNSCPKPDFICESRFMRVPINDNYCEKLLPWLDKSIEFIDKAKLSSCQVIV
190 200 210 220 230 240
110 120 130 140 150 160
pF1KE5 YCKNGRSRSAAVCTAYLMRHRGLSLAKAFQMVKSARPVAEPNPGFWSQLQKYEEALQAQS
.: : ::::.. ::.:. :.: :...::. :: :: .: .:: .::..:. .
CCDS77 HCLAGISRSATIAIAYIMKTMGMSSDDAYRFVKDRRPSISPNFNFLGQLLEYERSLKLLA
250 260 270 280 290 300
170
pF1KE5 CLQGEPPALGLGPEA
:::.: . . ::
CCDS77 ALQGDPGTPSGTPEPPPSPAAGAPLPRLPPPTSESAATGNAAAREGGLSAGGEPPAPPTP
310 320 330 340 350 360
>>CCDS13193.1 DUSP15 gene_id:128853|Hs108|chr20 (235 aa)
initn: 249 init1: 233 opt: 298 Z-score: 332.3 bits: 68.4 E(32554): 3.5e-12
Smith-Waterman score: 298; 34.1% identity (64.4% similar) in 135 aa overlap (19-153:5-138)
10 20 30 40 50 60
pF1KE5 MGPAEAGRRGAASPVPPPLVRVAPSLFLGSARAAGAEEQLARAGVTLCVNVSRQQPGPRA
...: :.:.::. : .::.: .: ... ...: :
CCDS13 MGNGMTKVLPGLYLGNFIDAKDLDQLGRNKITHIISI-HESPQPLL
10 20 30 40
70 80 90 100 110 120
pF1KE5 PGVAELRVPVFDDPAEDLLAHLEPTCAAMEAAVRAGGACLVYCKNGRSRSAAVCTAYLMR
.. ::.:: : : . :.. .. :: :::.: : :::... :::.:
CCDS13 QDITYLRIPVADTPEVPIKKHFKECINFIHCCRLNGGNCLVHCFAGISRSTTIVTAYVMT
50 60 70 80 90 100
130 140 150 160 170
pF1KE5 HRGLSLAKAFQMVKSARPVAEPNPGFWSQLQKYEEALQAQSCLQGEPPALGLGPEA
::. ... .:..::.:.::::: .::...
CCDS13 VTGLGWRDVLEAIKATRPIANPNPGFRQQLEEFGWASSQKLRRQLEERFGESPFRDEEEL
110 120 130 140 150 160
CCDS13 RALLPLCKRCRQGSATSASSAGPHSAASEGTVQRLVPRTPREAHRPLPLLARVKQTFSCL
170 180 190 200 210 220
>>CCDS4380.1 DUSP1 gene_id:1843|Hs108|chr5 (367 aa)
initn: 286 init1: 266 opt: 298 Z-score: 329.6 bits: 68.6 E(32554): 4.9e-12
Smith-Waterman score: 298; 32.4% identity (60.1% similar) in 173 aa overlap (4-172:157-328)
10 20 30
pF1KE5 MGPAEAGRRGAASPVPP---PLVRVAPSLFLGS
::.: . ..:. : :.. : :.:::
CCDS43 AFSASCPELCSKQSTPMGLSLPLSTSVPDSAESGCSSCSTPLYDQGGP-VEILPFLYLGS
130 140 150 160 170 180
40 50 60 70 80 90
pF1KE5 ARAAGAEEQLARAGVTLCVNVSRQQPGPRAPGVAELRVPVFDDPAEDLLAHLEPTCAAME
: :. ...: :.: .::: . :. .:: :. :. . .. . ..
CCDS43 AYHASRKDMLDALGITALINVSANCPNHFEGHYQYKSIPVEDNHKADISSWFNEAIDFID
190 200 210 220 230 240
100 110 120 130 140 150
pF1KE5 AAVRAGGACLVYCKNGRSRSAAVCTAYLMRHRGLSLAKAFQMVKSARPVAEPNPGFWSQL
. ::: .:.:. : ::::..: ::::: ..: .::..::. : . :: .: .::
CCDS43 SIKNAGGRVFVHCQAGISRSATICLAYLMRTNRVKLDEAFEFVKQRRSIISPNFSFMGQL
250 260 270 280 290 300
160 170
pF1KE5 QKYEEALQAQSC-LQGEPPALGLGPEA
..: . : : .. ::...
CCDS43 LQFESQVLAPHCSAEAGSPAMAVLDRGTSTTTVFNFPVSIPVHSTNSALSYLQSPITTSP
310 320 330 340 350 360
>>CCDS8157.1 SSH3 gene_id:54961|Hs108|chr11 (659 aa)
initn: 293 init1: 267 opt: 301 Z-score: 329.4 bits: 69.4 E(32554): 5e-12
Smith-Waterman score: 301; 38.9% identity (59.2% similar) in 157 aa overlap (21-175:331-486)
10 20 30 40 50
pF1KE5 MGPAEAGRRGAASPVPPPLVRVAPSLFLGSARAAGAEEQLARAGVTLCVN
:. : :.::: :. :.: : :: .:
CCDS81 ELRLGLPLQQYRDFIDNQMLLLVAQRDRASRIFPHLYLGSEWNAANLEELQRNRVTHILN
310 320 330 340 350 360
60 70 80 90 100 110
pF1KE5 VSRQQPGPRAPGVAELRVPVFDDPAEDLLAHLEPTCAAMEAAVRAGGACLVYCKNGRSRS
..:. . . : ..:. . .:: : . : .::: : ::.:: : :::
CCDS81 MAREIDNFYPERFTYHNVRLWDEESAQLLPHWKETHRFIEAARAQGTHVLVHCKMGVSRS
370 380 390 400 410 420
120 130 140 150 160
pF1KE5 AAVCTAYLMRHRGLSLAKAFQMVKSARPVAEPNPGFWSQLQKYEEALQA--QSCLQGEPP
::. :: :.. :: .:.. :. ::.:.::::: ::: :. : : :: . :
CCDS81 AATVLAYAMKQYECSLEQALRHVQELRPIARPNPGFLRQLQIYQGILTASRQSHVW-EQK
430 440 450 460 470
170
pF1KE5 ALGLGPEA
. :..::
CCDS81 VGGVSPEEHPAPEVSTPFPPLPPEPEGGGEEKVVGMEESQAAPKEEPGPRPRINLRGVMR
480 490 500 510 520 530
>>CCDS8650.1 DUSP16 gene_id:80824|Hs108|chr12 (665 aa)
initn: 226 init1: 226 opt: 299 Z-score: 327.2 bits: 69.0 E(32554): 6.7e-12
Smith-Waterman score: 299; 35.3% identity (58.8% similar) in 153 aa overlap (21-172:161-313)
10 20 30 40 50
pF1KE5 MGPAEAGRRGAASPVPPPLVRVAPSLFLGSARAAGAEEQLARAGVTLCVN
:. :.:.:: : . .: . . :. .:
CCDS86 CFPGLCEGKSTLVPTCISQPCLPVANIGPTRILPNLYLGCQRDVLNKELMQQNGIGYVLN
140 150 160 170 180 190
60 70 80 90 100
pF1KE5 VSRQQPGPR-APGVAELRVPVFDDPAEDLLAHLEPTCAAMEAAVRAGGACLVYCKNGRSR
.: : : : ::::: :. : .: :. . .: : ..: ::.: : ::
CCDS86 ASNTCPKPDFIPESHFLRVPVNDSFCEKILPWLDKSVDFIEKAKASNGCVLVHCLAGISR
200 210 220 230 240 250
110 120 130 140 150 160
pF1KE5 SAAVCTAYLMRHRGLSLAKAFQMVKSARPVAEPNPGFWSQLQKYEEALQAQSCLQGEPPA
::.. ::.:.. .:: .:...:: ::. :: .: .:: ::. .. :. .:
CCDS86 SATIAIAYIMKRMDMSLDEAYRFVKEKRPTISPNFNFLGQLLDYEKKIKNQTGASGPKSK
260 270 280 290 300 310
170
pF1KE5 LGLGPEA
: :
CCDS86 LKLLHLEKPNEPVPAVSEGGQKSETPLSPPCADSATSEAAGQRPVHPASVPSVPSVQPSL
320 330 340 350 360 370
>>CCDS82607.1 DUSP15 gene_id:128853|Hs108|chr20 (232 aa)
initn: 249 init1: 233 opt: 292 Z-score: 325.8 bits: 67.2 E(32554): 7.9e-12
Smith-Waterman score: 292; 34.8% identity (63.6% similar) in 132 aa overlap (22-153:5-135)
10 20 30 40 50 60
pF1KE5 MGPAEAGRRGAASPVPPPLVRVAPSLFLGSARAAGAEEQLARAGVTLCVNVSRQQPGPRA
: :.:.::. : .::.: .: ... ...: :
CCDS82 MTEGVLPGLYLGNFIDAKDLDQLGRNKITHIISI-HESPQPLL
10 20 30 40
70 80 90 100 110 120
pF1KE5 PGVAELRVPVFDDPAEDLLAHLEPTCAAMEAAVRAGGACLVYCKNGRSRSAAVCTAYLMR
.. ::.:: : : . :.. .. :: :::.: : :::... :::.:
CCDS82 QDITYLRIPVADTPEVPIKKHFKECINFIHCCRLNGGNCLVHCFAGISRSTTIVTAYVMT
50 60 70 80 90 100
130 140 150 160 170
pF1KE5 HRGLSLAKAFQMVKSARPVAEPNPGFWSQLQKYEEALQAQSCLQGEPPALGLGPEA
::. ... .:..::.:.::::: .::...
CCDS82 VTGLGWRDVLEAIKATRPIANPNPGFRQQLEEFGWASSQKLRRQLEERFGESPFRDEEEL
110 120 130 140 150 160
CCDS82 RALLPLCKRCRQGSATSASSAGPHSAASEGTVQRLVPRTPREAHRPLPLLARVKQTFSCL
170 180 190 200 210 220
176 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 04:47:10 2016 done: Tue Nov 8 04:47:10 2016
Total Scan time: 1.860 Total Display time: -0.030
Function used was FASTA [36.3.4 Apr, 2011]