Result of FASTA (omim) for
pFN21AE5073
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5073, 129 aa
1>>>pF1KE5073 129 - 129 aa - 129 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.7362+/-0.000285; mu= 14.5235+/- 0.018
mean_var=75.9016+/-15.890, 0's: 0 Z-trim(118.7): 39 B-trim: 1721 in 1/52
Lambda= 0.147214
statistics sampled from 31788 (31837) to 31788 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.73), E-opt: 0.2 (0.373), width: 16
Scan time: 3.620
The best scores are: opt bits E(85289)
NP_787109 (OMIM: 605267,613873) junctophilin-2 iso ( 129) 973 215.0 2.8e-56
XP_006723896 (OMIM: 605267,613873) PREDICTED: junc ( 147) 952 210.6 6.7e-55
NP_065166 (OMIM: 605267,613873) junctophilin-2 iso ( 696) 953 211.4 1.7e-54
NP_001258534 (OMIM: 605268,606438) junctophilin-3 ( 150) 824 183.4 1e-46
XP_005251332 (OMIM: 605266,607831) PREDICTED: junc ( 661) 830 185.3 1.2e-46
NP_001304759 (OMIM: 605266,607831) junctophilin-1 ( 661) 830 185.3 1.2e-46
NP_065698 (OMIM: 605266,607831) junctophilin-1 [Ho ( 661) 830 185.3 1.2e-46
XP_005251331 (OMIM: 605266,607831) PREDICTED: junc ( 661) 830 185.3 1.2e-46
NP_065706 (OMIM: 605268,606438) junctophilin-3 iso ( 748) 824 184.1 3.2e-46
XP_016878973 (OMIM: 605268,606438) PREDICTED: junc ( 148) 816 181.7 3.3e-46
XP_016878972 (OMIM: 605268,606438) PREDICTED: junc ( 176) 816 181.7 3.8e-46
NP_001258533 (OMIM: 605268,606438) junctophilin-3 ( 186) 816 181.8 3.9e-46
XP_011528088 (OMIM: 609314,615481) PREDICTED: radi ( 285) 240 59.6 3.5e-09
NP_543136 (OMIM: 609314,615481) radial spoke head ( 309) 240 59.7 3.7e-09
XP_016860061 (OMIM: 205100,606352,606353,607225) P ( 863) 211 53.9 5.5e-07
XP_016860060 (OMIM: 205100,606352,606353,607225) P ( 968) 211 54.0 5.9e-07
XP_006712718 (OMIM: 205100,606352,606353,607225) P ( 969) 211 54.0 5.9e-07
XP_016860059 (OMIM: 205100,606352,606353,607225) P (1342) 211 54.1 7.4e-07
XP_011509832 (OMIM: 205100,606352,606353,607225) P (1544) 211 54.2 8.2e-07
XP_016860058 (OMIM: 205100,606352,606353,607225) P (1656) 211 54.2 8.6e-07
XP_006712717 (OMIM: 205100,606352,606353,607225) P (1657) 211 54.2 8.6e-07
NP_065970 (OMIM: 205100,606352,606353,607225) alsi (1657) 211 54.2 8.6e-07
NP_001273435 (OMIM: 609314,615481) radial spoke he ( 271) 174 45.6 5.7e-05
XP_006713157 (OMIM: 612402) PREDICTED: ALS2 C-term ( 521) 155 41.8 0.0015
XP_016861609 (OMIM: 612402) PREDICTED: ALS2 C-term ( 752) 155 42.0 0.0019
XP_006713154 (OMIM: 612402) PREDICTED: ALS2 C-term ( 753) 155 42.0 0.0019
NP_667340 (OMIM: 612402) ALS2 C-terminal-like prot ( 953) 155 42.1 0.0022
NP_001177636 (OMIM: 612402) ALS2 C-terminal-like p ( 953) 155 42.1 0.0022
>>NP_787109 (OMIM: 605267,613873) junctophilin-2 isoform (129 aa)
initn: 973 init1: 973 opt: 973 Z-score: 1131.4 bits: 215.0 E(85289): 2.8e-56
Smith-Waterman score: 973; 100.0% identity (100.0% similar) in 129 aa overlap (1-129:1-129)
10 20 30 40 50 60
pF1KE5 MSGGRFDFDDGGAYCGGWEGGKAHGHGLCTGPKGQGEYSGSWNFGFEVAGVYTWPSGNTF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_787 MSGGRFDFDDGGAYCGGWEGGKAHGHGLCTGPKGQGEYSGSWNFGFEVAGVYTWPSGNTF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 EGYWSQGKRHGLGIETKGRWLYKGEWTHGFKGRYGIRQSSSSGAKYEGTWNNGLQDGYGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_787 EGYWSQGKRHGLGIETKGRWLYKGEWTHGFKGRYGIRQSSSSGAKYEGTWNNGLQDGYGT
70 80 90 100 110 120
pF1KE5 ETYADGGMC
:::::::::
NP_787 ETYADGGMC
>>XP_006723896 (OMIM: 605267,613873) PREDICTED: junctoph (147 aa)
initn: 945 init1: 945 opt: 952 Z-score: 1106.6 bits: 210.6 E(85289): 6.7e-55
Smith-Waterman score: 952; 98.4% identity (98.4% similar) in 129 aa overlap (1-129:1-129)
10 20 30 40 50 60
pF1KE5 MSGGRFDFDDGGAYCGGWEGGKAHGHGLCTGPKGQGEYSGSWNFGFEVAGVYTWPSGNTF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MSGGRFDFDDGGAYCGGWEGGKAHGHGLCTGPKGQGEYSGSWNFGFEVAGVYTWPSGNTF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 EGYWSQGKRHGLGIETKGRWLYKGEWTHGFKGRYGIRQSSSSGAKYEGTWNNGLQDGYGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EGYWSQGKRHGLGIETKGRWLYKGEWTHGFKGRYGIRQSSSSGAKYEGTWNNGLQDGYGT
70 80 90 100 110 120
pF1KE5 ETYADGGMC
:::::: :
XP_006 ETYADGVKCYKGNSSLPNWRGQRISGW
130 140
>>NP_065166 (OMIM: 605267,613873) junctophilin-2 isoform (696 aa)
initn: 953 init1: 953 opt: 953 Z-score: 1099.3 bits: 211.4 E(85289): 1.7e-54
Smith-Waterman score: 953; 100.0% identity (100.0% similar) in 127 aa overlap (1-127:1-127)
10 20 30 40 50 60
pF1KE5 MSGGRFDFDDGGAYCGGWEGGKAHGHGLCTGPKGQGEYSGSWNFGFEVAGVYTWPSGNTF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 MSGGRFDFDDGGAYCGGWEGGKAHGHGLCTGPKGQGEYSGSWNFGFEVAGVYTWPSGNTF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 EGYWSQGKRHGLGIETKGRWLYKGEWTHGFKGRYGIRQSSSSGAKYEGTWNNGLQDGYGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 EGYWSQGKRHGLGIETKGRWLYKGEWTHGFKGRYGIRQSSSSGAKYEGTWNNGLQDGYGT
70 80 90 100 110 120
pF1KE5 ETYADGGMC
:::::::
NP_065 ETYADGGTYQGQFTNGMRHGYGVRQSVPYGMAVVVRSPLRTSLSSLRSEHSNGTVAPDSP
130 140 150 160 170 180
>>NP_001258534 (OMIM: 605268,606438) junctophilin-3 isof (150 aa)
initn: 824 init1: 824 opt: 824 Z-score: 959.6 bits: 183.4 E(85289): 1e-46
Smith-Waterman score: 824; 80.2% identity (96.0% similar) in 126 aa overlap (2-127:3-128)
10 20 30 40 50
pF1KE5 MSGGRFDFDDGGAYCGGWEGGKAHGHGLCTGPKGQGEYSGSWNFGFEVAGVYTWPSGNT
:::::.:::::.:::::: :::::::.::::::::::.:::. :::: ::::::::::
NP_001 MSSGGRFNFDDGGSYCGGWEDGKAHGHGVCTGPKGQGEYTGSWSHGFEVLGVYTWPSGNT
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE5 FEGYWSQGKRHGLGIETKGRWLYKGEWTHGFKGRYGIRQSSSSGAKYEGTWNNGLQDGYG
..: :.::::::.:.:.::.:.::::::::::::::.:. ...::::::::.::::::::
NP_001 YQGTWAQGKRHGIGLESKGKWVYKGEWTHGFKGRYGVRECAGNGAKYEGTWSNGLQDGYG
70 80 90 100 110 120
120
pF1KE5 TETYADGGMC
::::.:::
NP_001 TETYSDGGGWTRTSAVEAGCWREEGGPSAQ
130 140 150
>>XP_005251332 (OMIM: 605266,607831) PREDICTED: junctoph (661 aa)
initn: 830 init1: 830 opt: 830 Z-score: 958.4 bits: 185.3 E(85289): 1.2e-46
Smith-Waterman score: 830; 80.3% identity (95.3% similar) in 127 aa overlap (1-127:1-127)
10 20 30 40 50 60
pF1KE5 MSGGRFDFDDGGAYCGGWEGGKAHGHGLCTGPKGQGEYSGSWNFGFEVAGVYTWPSGNTF
:.::::::::::.:::::: :::::::.::::::::::::::. ::::.: ::::::::.
XP_005 MTGGRFDFDDGGTYCGGWEEGKAHGHGICTGPKGQGEYSGSWSHGFEVVGGYTWPSGNTY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 EGYWSQGKRHGLGIETKGRWLYKGEWTHGFKGRYGIRQSSSSGAKYEGTWNNGLQDGYGT
.:::.::::::::.::::.:.:.:::.::::::::.::: . :.:::::.::::::::.
XP_005 QGYWAQGKRHGLGVETKGKWMYRGEWSHGFKGRYGVRQSLCTPARYEGTWSNGLQDGYGV
70 80 90 100 110 120
pF1KE5 ETYADGGMC
:::.:::
XP_005 ETYGDGGTYQGQWAGGMRHGYGVRQSVPYGMATVIRSPLRTSLASLRSEQSNGSVLHDAA
130 140 150 160 170 180
>>NP_001304759 (OMIM: 605266,607831) junctophilin-1 [Hom (661 aa)
initn: 830 init1: 830 opt: 830 Z-score: 958.4 bits: 185.3 E(85289): 1.2e-46
Smith-Waterman score: 830; 80.3% identity (95.3% similar) in 127 aa overlap (1-127:1-127)
10 20 30 40 50 60
pF1KE5 MSGGRFDFDDGGAYCGGWEGGKAHGHGLCTGPKGQGEYSGSWNFGFEVAGVYTWPSGNTF
:.::::::::::.:::::: :::::::.::::::::::::::. ::::.: ::::::::.
NP_001 MTGGRFDFDDGGTYCGGWEEGKAHGHGICTGPKGQGEYSGSWSHGFEVVGGYTWPSGNTY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 EGYWSQGKRHGLGIETKGRWLYKGEWTHGFKGRYGIRQSSSSGAKYEGTWNNGLQDGYGT
.:::.::::::::.::::.:.:.:::.::::::::.::: . :.:::::.::::::::.
NP_001 QGYWAQGKRHGLGVETKGKWMYRGEWSHGFKGRYGVRQSLCTPARYEGTWSNGLQDGYGV
70 80 90 100 110 120
pF1KE5 ETYADGGMC
:::.:::
NP_001 ETYGDGGTYQGQWAGGMRHGYGVRQSVPYGMATVIRSPLRTSLASLRSEQSNGSVLHDAA
130 140 150 160 170 180
>>NP_065698 (OMIM: 605266,607831) junctophilin-1 [Homo s (661 aa)
initn: 830 init1: 830 opt: 830 Z-score: 958.4 bits: 185.3 E(85289): 1.2e-46
Smith-Waterman score: 830; 80.3% identity (95.3% similar) in 127 aa overlap (1-127:1-127)
10 20 30 40 50 60
pF1KE5 MSGGRFDFDDGGAYCGGWEGGKAHGHGLCTGPKGQGEYSGSWNFGFEVAGVYTWPSGNTF
:.::::::::::.:::::: :::::::.::::::::::::::. ::::.: ::::::::.
NP_065 MTGGRFDFDDGGTYCGGWEEGKAHGHGICTGPKGQGEYSGSWSHGFEVVGGYTWPSGNTY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 EGYWSQGKRHGLGIETKGRWLYKGEWTHGFKGRYGIRQSSSSGAKYEGTWNNGLQDGYGT
.:::.::::::::.::::.:.:.:::.::::::::.::: . :.:::::.::::::::.
NP_065 QGYWAQGKRHGLGVETKGKWMYRGEWSHGFKGRYGVRQSLCTPARYEGTWSNGLQDGYGV
70 80 90 100 110 120
pF1KE5 ETYADGGMC
:::.:::
NP_065 ETYGDGGTYQGQWAGGMRHGYGVRQSVPYGMATVIRSPLRTSLASLRSEQSNGSVLHDAA
130 140 150 160 170 180
>>XP_005251331 (OMIM: 605266,607831) PREDICTED: junctoph (661 aa)
initn: 830 init1: 830 opt: 830 Z-score: 958.4 bits: 185.3 E(85289): 1.2e-46
Smith-Waterman score: 830; 80.3% identity (95.3% similar) in 127 aa overlap (1-127:1-127)
10 20 30 40 50 60
pF1KE5 MSGGRFDFDDGGAYCGGWEGGKAHGHGLCTGPKGQGEYSGSWNFGFEVAGVYTWPSGNTF
:.::::::::::.:::::: :::::::.::::::::::::::. ::::.: ::::::::.
XP_005 MTGGRFDFDDGGTYCGGWEEGKAHGHGICTGPKGQGEYSGSWSHGFEVVGGYTWPSGNTY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 EGYWSQGKRHGLGIETKGRWLYKGEWTHGFKGRYGIRQSSSSGAKYEGTWNNGLQDGYGT
.:::.::::::::.::::.:.:.:::.::::::::.::: . :.:::::.::::::::.
XP_005 QGYWAQGKRHGLGVETKGKWMYRGEWSHGFKGRYGVRQSLCTPARYEGTWSNGLQDGYGV
70 80 90 100 110 120
pF1KE5 ETYADGGMC
:::.:::
XP_005 ETYGDGGTYQGQWAGGMRHGYGVRQSVPYGMATVIRSPLRTSLASLRSEQSNGSVLHDAA
130 140 150 160 170 180
>>NP_065706 (OMIM: 605268,606438) junctophilin-3 isoform (748 aa)
initn: 824 init1: 824 opt: 824 Z-score: 950.8 bits: 184.1 E(85289): 3.2e-46
Smith-Waterman score: 824; 80.2% identity (96.0% similar) in 126 aa overlap (2-127:3-128)
10 20 30 40 50
pF1KE5 MSGGRFDFDDGGAYCGGWEGGKAHGHGLCTGPKGQGEYSGSWNFGFEVAGVYTWPSGNT
:::::.:::::.:::::: :::::::.::::::::::.:::. :::: ::::::::::
NP_065 MSSGGRFNFDDGGSYCGGWEDGKAHGHGVCTGPKGQGEYTGSWSHGFEVLGVYTWPSGNT
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE5 FEGYWSQGKRHGLGIETKGRWLYKGEWTHGFKGRYGIRQSSSSGAKYEGTWNNGLQDGYG
..: :.::::::.:.:.::.:.::::::::::::::.:. ...::::::::.::::::::
NP_065 YQGTWAQGKRHGIGLESKGKWVYKGEWTHGFKGRYGVRECAGNGAKYEGTWSNGLQDGYG
70 80 90 100 110 120
120
pF1KE5 TETYADGGMC
::::.:::
NP_065 TETYSDGGTYQGQWVGGMRQGYGVRQSVPYGMAAVIRSPLRTSINSLRSEHTNGTALHPD
130 140 150 160 170 180
>>XP_016878973 (OMIM: 605268,606438) PREDICTED: junctoph (148 aa)
initn: 816 init1: 816 opt: 816 Z-score: 950.5 bits: 181.7 E(85289): 3.3e-46
Smith-Waterman score: 816; 80.0% identity (96.0% similar) in 125 aa overlap (2-126:3-127)
10 20 30 40 50
pF1KE5 MSGGRFDFDDGGAYCGGWEGGKAHGHGLCTGPKGQGEYSGSWNFGFEVAGVYTWPSGNT
:::::.:::::.:::::: :::::::.::::::::::.:::. :::: ::::::::::
XP_016 MSSGGRFNFDDGGSYCGGWEDGKAHGHGVCTGPKGQGEYTGSWSHGFEVLGVYTWPSGNT
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE5 FEGYWSQGKRHGLGIETKGRWLYKGEWTHGFKGRYGIRQSSSSGAKYEGTWNNGLQDGYG
..: :.::::::.:.:.::.:.::::::::::::::.:. ...::::::::.::::::::
XP_016 YQGTWAQGKRHGIGLESKGKWVYKGEWTHGFKGRYGVRECAGNGAKYEGTWSNGLQDGYG
70 80 90 100 110 120
120
pF1KE5 TETYADGGMC
::::.::
XP_016 TETYSDGVIAEKQMWLKGTPTHVGREAV
130 140
129 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 04:46:37 2016 done: Tue Nov 8 04:46:37 2016
Total Scan time: 3.620 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]