Result of FASTA (omim) for
pFN21AE5023
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5023, 467 aa
1>>>pF1KE5023 467 - 467 aa - 467 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.0091+/-0.000313; mu= 20.6008+/- 0.020
mean_var=85.2671+/-16.822, 0's: 0 Z-trim(117.6): 207 B-trim: 250 in 1/51
Lambda= 0.138894
statistics sampled from 29458 (29718) to 29458 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.705), E-opt: 0.2 (0.348), width: 16
Scan time: 8.100
The best scores are: opt bits E(85289)
XP_016881194 (OMIM: 605696) PREDICTED: potassium v ( 466) 3116 634.2 2.3e-181
NP_036415 (OMIM: 605696) potassium voltage-gated c ( 466) 3116 634.2 2.3e-181
XP_011524222 (OMIM: 605696) PREDICTED: potassium v ( 466) 3116 634.2 2.3e-181
XP_011524220 (OMIM: 605696) PREDICTED: potassium v ( 466) 3116 634.2 2.3e-181
XP_016881193 (OMIM: 605696) PREDICTED: potassium v ( 509) 3116 634.2 2.4e-181
NP_758857 (OMIM: 607603) potassium voltage-gated c ( 519) 1681 346.7 9e-95
XP_011527103 (OMIM: 603788) PREDICTED: potassium v ( 513) 1286 267.5 6e-71
NP_002228 (OMIM: 603788) potassium voltage-gated c ( 513) 1286 267.5 6e-71
XP_011527107 (OMIM: 603788) PREDICTED: potassium v ( 513) 1286 267.5 6e-71
XP_011527108 (OMIM: 603788) PREDICTED: potassium v ( 513) 1286 267.5 6e-71
XP_006723848 (OMIM: 603788) PREDICTED: potassium v ( 513) 1286 267.5 6e-71
XP_011527104 (OMIM: 603788) PREDICTED: potassium v ( 513) 1286 267.5 6e-71
XP_011527105 (OMIM: 603788) PREDICTED: potassium v ( 513) 1286 267.5 6e-71
XP_011527102 (OMIM: 603788) PREDICTED: potassium v ( 513) 1286 267.5 6e-71
XP_011527106 (OMIM: 603788) PREDICTED: potassium v ( 513) 1286 267.5 6e-71
NP_758847 (OMIM: 606767) potassium voltage-gated c ( 425) 1149 240.0 9.7e-63
NP_004761 (OMIM: 607738) potassium voltage-gated c ( 911) 1113 233.1 2.4e-60
XP_011527101 (OMIM: 600397,616056) PREDICTED: pota ( 858) 1084 227.3 1.3e-58
XP_006723847 (OMIM: 600397,616056) PREDICTED: pota ( 858) 1084 227.3 1.3e-58
NP_004966 (OMIM: 600397,616056) potassium voltage- ( 858) 1084 227.3 1.3e-58
NP_002227 (OMIM: 603787) potassium voltage-gated c ( 494) 872 184.5 5.5e-46
NP_055194 (OMIM: 608164) potassium voltage-gated c ( 500) 855 181.1 5.9e-45
NP_001269357 (OMIM: 603888) potassium voltage-gate ( 491) 837 177.5 7.1e-44
XP_016859548 (OMIM: 603888) PREDICTED: potassium v ( 491) 837 177.5 7.1e-44
NP_002243 (OMIM: 603888) potassium voltage-gated c ( 491) 837 177.5 7.1e-44
XP_011531127 (OMIM: 603888) PREDICTED: potassium v ( 491) 837 177.5 7.1e-44
NP_579875 (OMIM: 606767) potassium voltage-gated c ( 436) 733 156.6 1.2e-37
NP_598004 (OMIM: 607604,610356) potassium voltage- ( 545) 726 155.3 3.8e-37
NP_065748 (OMIM: 602906) potassium voltage-gated c ( 477) 625 135.0 4.2e-31
NP_002224 (OMIM: 176266) potassium voltage-gated c ( 653) 626 135.4 4.6e-31
NP_001309728 (OMIM: 602905) potassium voltage-gate ( 526) 609 131.9 4.2e-30
NP_002242 (OMIM: 602905) potassium voltage-gated c ( 526) 609 131.9 4.2e-30
XP_016883335 (OMIM: 602905) PREDICTED: potassium v ( 527) 609 131.9 4.2e-30
NP_000208 (OMIM: 160120,176260) potassium voltage- ( 495) 582 126.4 1.7e-28
NP_114092 (OMIM: 176268) potassium voltage-gated c ( 456) 581 126.2 1.9e-28
XP_011539702 (OMIM: 176262,616366) PREDICTED: pota ( 499) 578 125.6 3e-28
NP_004965 (OMIM: 176262,616366) potassium voltage- ( 499) 578 125.6 3e-28
XP_011539701 (OMIM: 176262,616366) PREDICTED: pota ( 499) 578 125.6 3e-28
XP_011539699 (OMIM: 176262,616366) PREDICTED: pota ( 499) 578 125.6 3e-28
XP_011539700 (OMIM: 176262,616366) PREDICTED: pota ( 499) 578 125.6 3e-28
XP_011539698 (OMIM: 176262,616366) PREDICTED: pota ( 499) 578 125.6 3e-28
XP_016856702 (OMIM: 176262,616366) PREDICTED: pota ( 499) 578 125.6 3e-28
NP_002223 (OMIM: 176263) potassium voltage-gated c ( 575) 565 123.1 2e-27
XP_016869470 (OMIM: 607738) PREDICTED: potassium v ( 666) 558 121.8 5.9e-27
XP_016869471 (OMIM: 607738) PREDICTED: potassium v ( 666) 558 121.8 5.9e-27
NP_005540 (OMIM: 602420) potassium voltage-gated c ( 511) 543 118.6 3.9e-26
NP_002225 (OMIM: 176267,612240) potassium voltage- ( 613) 542 118.5 5.1e-26
XP_016874761 (OMIM: 176257) PREDICTED: potassium v ( 529) 536 117.3 1.1e-25
NP_002226 (OMIM: 176257) potassium voltage-gated c ( 529) 536 117.3 1.1e-25
XP_011519257 (OMIM: 176257) PREDICTED: potassium v ( 529) 536 117.3 1.1e-25
>>XP_016881194 (OMIM: 605696) PREDICTED: potassium volta (466 aa)
initn: 3052 init1: 3052 opt: 3116 Z-score: 3377.1 bits: 634.2 E(85289): 2.3e-181
Smith-Waterman score: 3116; 99.8% identity (99.8% similar) in 467 aa overlap (1-467:1-466)
10 20 30 40 50 60
pF1KE5 MEPWPCSPGGGGGGTRARHVIINVGGCRVRLAWAALARCPLARLERLRACRGHDDLLRVC
::::::::::::: ::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEPWPCSPGGGGG-TRARHVIINVGGCRVRLAWAALARCPLARLERLRACRGHDDLLRVC
10 20 30 40 50
70 80 90 100 110 120
pF1KE5 DDYDVSRDEFFFDRSPCAFRAIVALLRAGKLRLLRGPCALAFRDELAYWGIDEARLERCC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DDYDVSRDEFFFDRSPCAFRAIVALLRAGKLRLLRGPCALAFRDELAYWGIDEARLERCC
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE5 LRRLRRREEEAAEARAGPTERGAQGSPARALGPRGRLQRGRRRLRDVVDNPHSGLAGKLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRRLRRREEEAAEARAGPTERGAQGSPARALGPRGRLQRGRRRLRDVVDNPHSGLAGKLF
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE5 ACVSVSFVAVTAVGLCLSTMPDIRAEEERGECSPKCRSLFVLETVCVAWFSFEFLLRSLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ACVSVSFVAVTAVGLCLSTMPDIRAEEERGECSPKCRSLFVLETVCVAWFSFEFLLRSLQ
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE5 AESKCAFLRAPLNIIDILALLPFYVSLLLGLAAGPGGTKLLERAGLVLRLLRALRVLYVM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AESKCAFLRAPLNIIDILALLPFYVSLLLGLAAGPGGTKLLERAGLVLRLLRALRVLYVM
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE5 RLARHSLGLRSLGLTMRRCAREFGLLLLFLCVAMALFAPLVHLAERELGARRDFSSVPAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RLARHSLGLRSLGLTMRRCAREFGLLLLFLCVAMALFAPLVHLAERELGARRDFSSVPAS
300 310 320 330 340 350
370 380 390 400 410 420
pF1KE5 YWWAVISMTTVGYGDMVPRSLPGQVVALSSILSGILLMAFPVTSIFHTFSRSYSELKEQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YWWAVISMTTVGYGDMVPRSLPGQVVALSSILSGILLMAFPVTSIFHTFSRSYSELKEQQ
360 370 380 390 400 410
430 440 450 460
pF1KE5 QRAASPEPALQEDSTHSATATEDSSQGPDSAGLADDSADALWVRAGR
:::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QRAASPEPALQEDSTHSATATEDSSQGPDSAGLADDSADALWVRAGR
420 430 440 450 460
>>NP_036415 (OMIM: 605696) potassium voltage-gated chann (466 aa)
initn: 3052 init1: 3052 opt: 3116 Z-score: 3377.1 bits: 634.2 E(85289): 2.3e-181
Smith-Waterman score: 3116; 99.8% identity (99.8% similar) in 467 aa overlap (1-467:1-466)
10 20 30 40 50 60
pF1KE5 MEPWPCSPGGGGGGTRARHVIINVGGCRVRLAWAALARCPLARLERLRACRGHDDLLRVC
::::::::::::: ::::::::::::::::::::::::::::::::::::::::::::::
NP_036 MEPWPCSPGGGGG-TRARHVIINVGGCRVRLAWAALARCPLARLERLRACRGHDDLLRVC
10 20 30 40 50
70 80 90 100 110 120
pF1KE5 DDYDVSRDEFFFDRSPCAFRAIVALLRAGKLRLLRGPCALAFRDELAYWGIDEARLERCC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 DDYDVSRDEFFFDRSPCAFRAIVALLRAGKLRLLRGPCALAFRDELAYWGIDEARLERCC
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE5 LRRLRRREEEAAEARAGPTERGAQGSPARALGPRGRLQRGRRRLRDVVDNPHSGLAGKLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 LRRLRRREEEAAEARAGPTERGAQGSPARALGPRGRLQRGRRRLRDVVDNPHSGLAGKLF
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE5 ACVSVSFVAVTAVGLCLSTMPDIRAEEERGECSPKCRSLFVLETVCVAWFSFEFLLRSLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 ACVSVSFVAVTAVGLCLSTMPDIRAEEERGECSPKCRSLFVLETVCVAWFSFEFLLRSLQ
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE5 AESKCAFLRAPLNIIDILALLPFYVSLLLGLAAGPGGTKLLERAGLVLRLLRALRVLYVM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 AESKCAFLRAPLNIIDILALLPFYVSLLLGLAAGPGGTKLLERAGLVLRLLRALRVLYVM
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE5 RLARHSLGLRSLGLTMRRCAREFGLLLLFLCVAMALFAPLVHLAERELGARRDFSSVPAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 RLARHSLGLRSLGLTMRRCAREFGLLLLFLCVAMALFAPLVHLAERELGARRDFSSVPAS
300 310 320 330 340 350
370 380 390 400 410 420
pF1KE5 YWWAVISMTTVGYGDMVPRSLPGQVVALSSILSGILLMAFPVTSIFHTFSRSYSELKEQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 YWWAVISMTTVGYGDMVPRSLPGQVVALSSILSGILLMAFPVTSIFHTFSRSYSELKEQQ
360 370 380 390 400 410
430 440 450 460
pF1KE5 QRAASPEPALQEDSTHSATATEDSSQGPDSAGLADDSADALWVRAGR
:::::::::::::::::::::::::::::::::::::::::::::::
NP_036 QRAASPEPALQEDSTHSATATEDSSQGPDSAGLADDSADALWVRAGR
420 430 440 450 460
>>XP_011524222 (OMIM: 605696) PREDICTED: potassium volta (466 aa)
initn: 3052 init1: 3052 opt: 3116 Z-score: 3377.1 bits: 634.2 E(85289): 2.3e-181
Smith-Waterman score: 3116; 99.8% identity (99.8% similar) in 467 aa overlap (1-467:1-466)
10 20 30 40 50 60
pF1KE5 MEPWPCSPGGGGGGTRARHVIINVGGCRVRLAWAALARCPLARLERLRACRGHDDLLRVC
::::::::::::: ::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MEPWPCSPGGGGG-TRARHVIINVGGCRVRLAWAALARCPLARLERLRACRGHDDLLRVC
10 20 30 40 50
70 80 90 100 110 120
pF1KE5 DDYDVSRDEFFFDRSPCAFRAIVALLRAGKLRLLRGPCALAFRDELAYWGIDEARLERCC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DDYDVSRDEFFFDRSPCAFRAIVALLRAGKLRLLRGPCALAFRDELAYWGIDEARLERCC
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE5 LRRLRRREEEAAEARAGPTERGAQGSPARALGPRGRLQRGRRRLRDVVDNPHSGLAGKLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRRLRRREEEAAEARAGPTERGAQGSPARALGPRGRLQRGRRRLRDVVDNPHSGLAGKLF
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE5 ACVSVSFVAVTAVGLCLSTMPDIRAEEERGECSPKCRSLFVLETVCVAWFSFEFLLRSLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ACVSVSFVAVTAVGLCLSTMPDIRAEEERGECSPKCRSLFVLETVCVAWFSFEFLLRSLQ
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE5 AESKCAFLRAPLNIIDILALLPFYVSLLLGLAAGPGGTKLLERAGLVLRLLRALRVLYVM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AESKCAFLRAPLNIIDILALLPFYVSLLLGLAAGPGGTKLLERAGLVLRLLRALRVLYVM
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE5 RLARHSLGLRSLGLTMRRCAREFGLLLLFLCVAMALFAPLVHLAERELGARRDFSSVPAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RLARHSLGLRSLGLTMRRCAREFGLLLLFLCVAMALFAPLVHLAERELGARRDFSSVPAS
300 310 320 330 340 350
370 380 390 400 410 420
pF1KE5 YWWAVISMTTVGYGDMVPRSLPGQVVALSSILSGILLMAFPVTSIFHTFSRSYSELKEQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YWWAVISMTTVGYGDMVPRSLPGQVVALSSILSGILLMAFPVTSIFHTFSRSYSELKEQQ
360 370 380 390 400 410
430 440 450 460
pF1KE5 QRAASPEPALQEDSTHSATATEDSSQGPDSAGLADDSADALWVRAGR
:::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QRAASPEPALQEDSTHSATATEDSSQGPDSAGLADDSADALWVRAGR
420 430 440 450 460
>>XP_011524220 (OMIM: 605696) PREDICTED: potassium volta (466 aa)
initn: 3052 init1: 3052 opt: 3116 Z-score: 3377.1 bits: 634.2 E(85289): 2.3e-181
Smith-Waterman score: 3116; 99.8% identity (99.8% similar) in 467 aa overlap (1-467:1-466)
10 20 30 40 50 60
pF1KE5 MEPWPCSPGGGGGGTRARHVIINVGGCRVRLAWAALARCPLARLERLRACRGHDDLLRVC
::::::::::::: ::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MEPWPCSPGGGGG-TRARHVIINVGGCRVRLAWAALARCPLARLERLRACRGHDDLLRVC
10 20 30 40 50
70 80 90 100 110 120
pF1KE5 DDYDVSRDEFFFDRSPCAFRAIVALLRAGKLRLLRGPCALAFRDELAYWGIDEARLERCC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DDYDVSRDEFFFDRSPCAFRAIVALLRAGKLRLLRGPCALAFRDELAYWGIDEARLERCC
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE5 LRRLRRREEEAAEARAGPTERGAQGSPARALGPRGRLQRGRRRLRDVVDNPHSGLAGKLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRRLRRREEEAAEARAGPTERGAQGSPARALGPRGRLQRGRRRLRDVVDNPHSGLAGKLF
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE5 ACVSVSFVAVTAVGLCLSTMPDIRAEEERGECSPKCRSLFVLETVCVAWFSFEFLLRSLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ACVSVSFVAVTAVGLCLSTMPDIRAEEERGECSPKCRSLFVLETVCVAWFSFEFLLRSLQ
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE5 AESKCAFLRAPLNIIDILALLPFYVSLLLGLAAGPGGTKLLERAGLVLRLLRALRVLYVM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AESKCAFLRAPLNIIDILALLPFYVSLLLGLAAGPGGTKLLERAGLVLRLLRALRVLYVM
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE5 RLARHSLGLRSLGLTMRRCAREFGLLLLFLCVAMALFAPLVHLAERELGARRDFSSVPAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RLARHSLGLRSLGLTMRRCAREFGLLLLFLCVAMALFAPLVHLAERELGARRDFSSVPAS
300 310 320 330 340 350
370 380 390 400 410 420
pF1KE5 YWWAVISMTTVGYGDMVPRSLPGQVVALSSILSGILLMAFPVTSIFHTFSRSYSELKEQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YWWAVISMTTVGYGDMVPRSLPGQVVALSSILSGILLMAFPVTSIFHTFSRSYSELKEQQ
360 370 380 390 400 410
430 440 450 460
pF1KE5 QRAASPEPALQEDSTHSATATEDSSQGPDSAGLADDSADALWVRAGR
:::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QRAASPEPALQEDSTHSATATEDSSQGPDSAGLADDSADALWVRAGR
420 430 440 450 460
>>XP_016881193 (OMIM: 605696) PREDICTED: potassium volta (509 aa)
initn: 3052 init1: 3052 opt: 3116 Z-score: 3376.6 bits: 634.2 E(85289): 2.4e-181
Smith-Waterman score: 3116; 99.8% identity (99.8% similar) in 467 aa overlap (1-467:44-509)
10 20 30
pF1KE5 MEPWPCSPGGGGGGTRARHVIINVGGCRVR
::::::::::::: ::::::::::::::::
XP_016 VFTGSLKENTLYLHRARSRAGAPRSGPALRMEPWPCSPGGGGG-TRARHVIINVGGCRVR
20 30 40 50 60 70
40 50 60 70 80 90
pF1KE5 LAWAALARCPLARLERLRACRGHDDLLRVCDDYDVSRDEFFFDRSPCAFRAIVALLRAGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAWAALARCPLARLERLRACRGHDDLLRVCDDYDVSRDEFFFDRSPCAFRAIVALLRAGK
80 90 100 110 120 130
100 110 120 130 140 150
pF1KE5 LRLLRGPCALAFRDELAYWGIDEARLERCCLRRLRRREEEAAEARAGPTERGAQGSPARA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRLLRGPCALAFRDELAYWGIDEARLERCCLRRLRRREEEAAEARAGPTERGAQGSPARA
140 150 160 170 180 190
160 170 180 190 200 210
pF1KE5 LGPRGRLQRGRRRLRDVVDNPHSGLAGKLFACVSVSFVAVTAVGLCLSTMPDIRAEEERG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGPRGRLQRGRRRLRDVVDNPHSGLAGKLFACVSVSFVAVTAVGLCLSTMPDIRAEEERG
200 210 220 230 240 250
220 230 240 250 260 270
pF1KE5 ECSPKCRSLFVLETVCVAWFSFEFLLRSLQAESKCAFLRAPLNIIDILALLPFYVSLLLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ECSPKCRSLFVLETVCVAWFSFEFLLRSLQAESKCAFLRAPLNIIDILALLPFYVSLLLG
260 270 280 290 300 310
280 290 300 310 320 330
pF1KE5 LAAGPGGTKLLERAGLVLRLLRALRVLYVMRLARHSLGLRSLGLTMRRCAREFGLLLLFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAAGPGGTKLLERAGLVLRLLRALRVLYVMRLARHSLGLRSLGLTMRRCAREFGLLLLFL
320 330 340 350 360 370
340 350 360 370 380 390
pF1KE5 CVAMALFAPLVHLAERELGARRDFSSVPASYWWAVISMTTVGYGDMVPRSLPGQVVALSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CVAMALFAPLVHLAERELGARRDFSSVPASYWWAVISMTTVGYGDMVPRSLPGQVVALSS
380 390 400 410 420 430
400 410 420 430 440 450
pF1KE5 ILSGILLMAFPVTSIFHTFSRSYSELKEQQQRAASPEPALQEDSTHSATATEDSSQGPDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ILSGILLMAFPVTSIFHTFSRSYSELKEQQQRAASPEPALQEDSTHSATATEDSSQGPDS
440 450 460 470 480 490
460
pF1KE5 AGLADDSADALWVRAGR
:::::::::::::::::
XP_016 AGLADDSADALWVRAGR
500
>>NP_758857 (OMIM: 607603) potassium voltage-gated chann (519 aa)
initn: 1710 init1: 754 opt: 1681 Z-score: 1822.4 bits: 346.7 E(85289): 9e-95
Smith-Waterman score: 1681; 57.7% identity (78.8% similar) in 449 aa overlap (18-459:59-506)
10 20 30 40
pF1KE5 MEPWPCSPGGGGGGTRARHVIINVGGCRVRLAWAALARCPLARLERL
....::::: : : :..: : ::.:: .:
NP_758 SPMETPSIKGLYYRRVRKVGALDASPVDLKKEILINVGGRRYLLPWSTLDRFPLSRLSKL
30 40 50 60 70 80
50 60 70 80 90 100
pF1KE5 RACRGHDDLLRVCDDYDVSRDEFFFDRSPCAFRAIVALLRAGKLRLLRGPCALAFRDELA
: ::........::::: . .:::::::: :: .::..: :::: ::. :::.:..:::
NP_758 RLCRSYEEIVQLCDDYDEDSQEFFFDRSPSAFGVIVSFLAAGKLVLLQEMCALSFQEELA
90 100 110 120 130 140
110 120 130 140 150 160
pF1KE5 YWGIDEARLERCCLRRLRRREEEAAEARAGPTER--GAQGSPARALGPRGRLQRGRRRLR
::::.::.:::::::.: :. :: : : : : . .: :::
NP_758 YWGIEEAHLERCCLRKLLRKLEELEELAKLHREDVLRQQRETRRPASHSSRWGLCMNRLR
150 160 170 180 190 200
170 180 190 200 210 220
pF1KE5 DVVDNPHSGLAGKLFACVSVSFVAVTAVGLCLSTMPDIRAEEERGECSPKCRSLFVLETV
..:.::.::: ::.:::.:. :::.:::.::.:::::.::::..:::: :: .:..::.
NP_758 EMVENPQSGLPGKVFACLSILFVATTAVSLCVSTMPDLRAEEDQGECSRKCYYIFIVETI
210 220 230 240 250 260
230 240 250 260 270 280
pF1KE5 CVAWFSFEFLLRSLQAESKCAFLRAPLNIIDILALLPFYVSLLLGLAAG-----PGGTKL
::::::.:: :: .::..:: :...:::::::::. :.:::: .. :.:..
NP_758 CVAWFSLEFCLRFVQAQDKCQFFQGPLNIIDILAISPYYVSLAVSEEPPEDGERPSGSSY
270 280 290 300 310 320
290 300 310 320 330 340
pF1KE5 LERAGLVLRLLRALRVLYVMRLARHSLGLRSLGLTMRRCAREFGLLLLFLCVAMALFAPL
::..:::::.:::::.:::::::::::::..::::.:::.:::::::::: ::..::.::
NP_758 LEKVGLVLRVLRALRILYVMRLARHSLGLQTLGLTVRRCTREFGLLLLFLAVAITLFSPL
330 340 350 360 370 380
350 360 370 380 390 400
pF1KE5 VHLAERELGARRDFSSVPASYWWAVISMTTVGYGDMVPRSLPGQVVALSSILSGILLMAF
:..::.: : .:.:.:::::::.:::::::::::::::.:::.:::::::::::.:::
NP_758 VYVAEKESGRVLEFTSIPASYWWAIISMTTVGYGDMVPRSVPGQMVALSSILSGILIMAF
390 400 410 420 430 440
410 420 430 440 450 460
pF1KE5 PVTSIFHTFSRSYSELKEQQQRAASPEPALQEDSTHSATATEDSSQGPDSAGLADDSADA
:.::::::::.:: :::..:.. . ::. . : : . . : .: :
NP_758 PATSIFHTFSHSYLELKKEQEQLQARLRHLQNTGPASECELLDPHVASEHE-LMNDVNDL
450 460 470 480 490 500
pF1KE5 LWVRAGR
NP_758 ILEGPALPIMHM
510
>>XP_011527103 (OMIM: 603788) PREDICTED: potassium volta (513 aa)
initn: 1714 init1: 763 opt: 1286 Z-score: 1394.7 bits: 267.5 E(85289): 6e-71
Smith-Waterman score: 1728; 59.6% identity (80.6% similar) in 453 aa overlap (16-459:61-511)
10 20 30 40
pF1KE5 MEPWPCSPGGGGGGTRARHVIINVGGCRVRLAWAALARCPLARLE
: :..:::::: . : :..: . ::.::
XP_011 QRQAIKGAFYRRAQRLRPQDEPRQGCQPEDRRRRIIINVGGIKYSLPWTTLDEFPLTRLG
40 50 60 70 80 90
50 60 70 80 90 100
pF1KE5 RLRACRGHDDLLRVCDDYDVSRDEFFFDRSPCAFRAIVALLRAGKLRLLRGPCALAFRDE
.:.:: . ::.: :::::::. .::::::.: :: .:...:::::::::: :::.:..:
XP_011 QLKACTNFDDILNVCDDYDVTCNEFFFDRNPGAFGTILTFLRAGKLRLLREMCALSFQEE
100 110 120 130 140 150
110 120 130 140 150 160
pF1KE5 LAYWGIDEARLERCCLRRLRRREEEAAEARAGPTERGAQGSPAR-ALGP---RGRLQRGR
: :::: : .:. :: :: .. :: :: : : : .: . :: .::: :
XP_011 LLYWGIAEDHLDGCCKRRYLQKIEEFAEMVEREEEDDALDSEGRDSEGPAEGEGRLGRCM
160 170 180 190 200 210
170 180 190 200 210 220
pF1KE5 RRLRDVVDNPHSGLAGKLFACVSVSFVAVTAVGLCLSTMPDIRAEEERGECSPKCRSLFV
:::::.:. ::::: ::.:::.:: ::.::::.: .::.:..: :::.:.:: :...:.
XP_011 RRLRDMVERPHSGLPGKVFACLSVLFVTVTAVNLSVSTLPSLREEEEQGHCSQMCHNVFI
220 230 240 250 260 270
230 240 250 260 270
pF1KE5 LETVCVAWFSFEFLLRSLQAESKCAFLRAPLNIIDILALLPFYVSLLL-GLAAG---PG-
.:.:::.:::.::::: .:: :: ::::.::..::..:.::.:..::. : ::: ::
XP_011 VESVCVGWFSLEFLLRLIQAPSKFAFLRSPLTLIDLVAILPYYITLLVDGAAAGRRKPGA
280 290 300 310 320 330
280 290 300 310 320 330
pF1KE5 GTKLLERAGLVLRLLRALRVLYVMRLARHSLGLRSLGLTMRRCAREFGLLLLFLCVAMAL
:.. :...:::::.:::::.:::::::::::::..:::: :::.:::::::::::::.::
XP_011 GNSYLDKVGLVLRVLRALRILYVMRLARHSLGLQTLGLTARRCTREFGLLLLFLCVAIAL
340 350 360 370 380 390
340 350 360 370 380 390
pF1KE5 FAPLVHLAERELGARRDFSSVPASYWWAVISMTTVGYGDMVPRSLPGQVVALSSILSGIL
::::... : :.. .:.:.:: ::::::.::::::::::::: :::::::::::::::
XP_011 FAPLLYVIENEMADSPEFTSIPACYWWAVITMTTVGYGDMVPRSTPGQVVALSSILSGIL
400 410 420 430 440 450
400 410 420 430 440 450
pF1KE5 LMAFPVTSIFHTFSRSYSELKEQQQRAASPEPALQEDSTHSATATEDSSQGPDSAGLADD
::::::::::::::::: :::..:.:. . . . . ....::. :: ..:
XP_011 LMAFPVTSIFHTFSRSYLELKQEQERVMFRRAQFLIKTKSQLSVSQDSDILFGSA--SSD
460 470 480 490 500
460
pF1KE5 SADALWVRAGR
. :
XP_011 TRDNN
510
>>NP_002228 (OMIM: 603788) potassium voltage-gated chann (513 aa)
initn: 1714 init1: 763 opt: 1286 Z-score: 1394.7 bits: 267.5 E(85289): 6e-71
Smith-Waterman score: 1728; 59.6% identity (80.6% similar) in 453 aa overlap (16-459:61-511)
10 20 30 40
pF1KE5 MEPWPCSPGGGGGGTRARHVIINVGGCRVRLAWAALARCPLARLE
: :..:::::: . : :..: . ::.::
NP_002 QRQAIKGAFYRRAQRLRPQDEPRQGCQPEDRRRRIIINVGGIKYSLPWTTLDEFPLTRLG
40 50 60 70 80 90
50 60 70 80 90 100
pF1KE5 RLRACRGHDDLLRVCDDYDVSRDEFFFDRSPCAFRAIVALLRAGKLRLLRGPCALAFRDE
.:.:: . ::.: :::::::. .::::::.: :: .:...:::::::::: :::.:..:
NP_002 QLKACTNFDDILNVCDDYDVTCNEFFFDRNPGAFGTILTFLRAGKLRLLREMCALSFQEE
100 110 120 130 140 150
110 120 130 140 150 160
pF1KE5 LAYWGIDEARLERCCLRRLRRREEEAAEARAGPTERGAQGSPAR-ALGP---RGRLQRGR
: :::: : .:. :: :: .. :: :: : : : .: . :: .::: :
NP_002 LLYWGIAEDHLDGCCKRRYLQKIEEFAEMVEREEEDDALDSEGRDSEGPAEGEGRLGRCM
160 170 180 190 200 210
170 180 190 200 210 220
pF1KE5 RRLRDVVDNPHSGLAGKLFACVSVSFVAVTAVGLCLSTMPDIRAEEERGECSPKCRSLFV
:::::.:. ::::: ::.:::.:: ::.::::.: .::.:..: :::.:.:: :...:.
NP_002 RRLRDMVERPHSGLPGKVFACLSVLFVTVTAVNLSVSTLPSLREEEEQGHCSQMCHNVFI
220 230 240 250 260 270
230 240 250 260 270
pF1KE5 LETVCVAWFSFEFLLRSLQAESKCAFLRAPLNIIDILALLPFYVSLLL-GLAAG---PG-
.:.:::.:::.::::: .:: :: ::::.::..::..:.::.:..::. : ::: ::
NP_002 VESVCVGWFSLEFLLRLIQAPSKFAFLRSPLTLIDLVAILPYYITLLVDGAAAGRRKPGA
280 290 300 310 320 330
280 290 300 310 320 330
pF1KE5 GTKLLERAGLVLRLLRALRVLYVMRLARHSLGLRSLGLTMRRCAREFGLLLLFLCVAMAL
:.. :...:::::.:::::.:::::::::::::..:::: :::.:::::::::::::.::
NP_002 GNSYLDKVGLVLRVLRALRILYVMRLARHSLGLQTLGLTARRCTREFGLLLLFLCVAIAL
340 350 360 370 380 390
340 350 360 370 380 390
pF1KE5 FAPLVHLAERELGARRDFSSVPASYWWAVISMTTVGYGDMVPRSLPGQVVALSSILSGIL
::::... : :.. .:.:.:: ::::::.::::::::::::: :::::::::::::::
NP_002 FAPLLYVIENEMADSPEFTSIPACYWWAVITMTTVGYGDMVPRSTPGQVVALSSILSGIL
400 410 420 430 440 450
400 410 420 430 440 450
pF1KE5 LMAFPVTSIFHTFSRSYSELKEQQQRAASPEPALQEDSTHSATATEDSSQGPDSAGLADD
::::::::::::::::: :::..:.:. . . . . ....::. :: ..:
NP_002 LMAFPVTSIFHTFSRSYLELKQEQERVMFRRAQFLIKTKSQLSVSQDSDILFGSA--SSD
460 470 480 490 500
460
pF1KE5 SADALWVRAGR
. :
NP_002 TRDNN
510
>>XP_011527107 (OMIM: 603788) PREDICTED: potassium volta (513 aa)
initn: 1714 init1: 763 opt: 1286 Z-score: 1394.7 bits: 267.5 E(85289): 6e-71
Smith-Waterman score: 1728; 59.6% identity (80.6% similar) in 453 aa overlap (16-459:61-511)
10 20 30 40
pF1KE5 MEPWPCSPGGGGGGTRARHVIINVGGCRVRLAWAALARCPLARLE
: :..:::::: . : :..: . ::.::
XP_011 QRQAIKGAFYRRAQRLRPQDEPRQGCQPEDRRRRIIINVGGIKYSLPWTTLDEFPLTRLG
40 50 60 70 80 90
50 60 70 80 90 100
pF1KE5 RLRACRGHDDLLRVCDDYDVSRDEFFFDRSPCAFRAIVALLRAGKLRLLRGPCALAFRDE
.:.:: . ::.: :::::::. .::::::.: :: .:...:::::::::: :::.:..:
XP_011 QLKACTNFDDILNVCDDYDVTCNEFFFDRNPGAFGTILTFLRAGKLRLLREMCALSFQEE
100 110 120 130 140 150
110 120 130 140 150 160
pF1KE5 LAYWGIDEARLERCCLRRLRRREEEAAEARAGPTERGAQGSPAR-ALGP---RGRLQRGR
: :::: : .:. :: :: .. :: :: : : : .: . :: .::: :
XP_011 LLYWGIAEDHLDGCCKRRYLQKIEEFAEMVEREEEDDALDSEGRDSEGPAEGEGRLGRCM
160 170 180 190 200 210
170 180 190 200 210 220
pF1KE5 RRLRDVVDNPHSGLAGKLFACVSVSFVAVTAVGLCLSTMPDIRAEEERGECSPKCRSLFV
:::::.:. ::::: ::.:::.:: ::.::::.: .::.:..: :::.:.:: :...:.
XP_011 RRLRDMVERPHSGLPGKVFACLSVLFVTVTAVNLSVSTLPSLREEEEQGHCSQMCHNVFI
220 230 240 250 260 270
230 240 250 260 270
pF1KE5 LETVCVAWFSFEFLLRSLQAESKCAFLRAPLNIIDILALLPFYVSLLL-GLAAG---PG-
.:.:::.:::.::::: .:: :: ::::.::..::..:.::.:..::. : ::: ::
XP_011 VESVCVGWFSLEFLLRLIQAPSKFAFLRSPLTLIDLVAILPYYITLLVDGAAAGRRKPGA
280 290 300 310 320 330
280 290 300 310 320 330
pF1KE5 GTKLLERAGLVLRLLRALRVLYVMRLARHSLGLRSLGLTMRRCAREFGLLLLFLCVAMAL
:.. :...:::::.:::::.:::::::::::::..:::: :::.:::::::::::::.::
XP_011 GNSYLDKVGLVLRVLRALRILYVMRLARHSLGLQTLGLTARRCTREFGLLLLFLCVAIAL
340 350 360 370 380 390
340 350 360 370 380 390
pF1KE5 FAPLVHLAERELGARRDFSSVPASYWWAVISMTTVGYGDMVPRSLPGQVVALSSILSGIL
::::... : :.. .:.:.:: ::::::.::::::::::::: :::::::::::::::
XP_011 FAPLLYVIENEMADSPEFTSIPACYWWAVITMTTVGYGDMVPRSTPGQVVALSSILSGIL
400 410 420 430 440 450
400 410 420 430 440 450
pF1KE5 LMAFPVTSIFHTFSRSYSELKEQQQRAASPEPALQEDSTHSATATEDSSQGPDSAGLADD
::::::::::::::::: :::..:.:. . . . . ....::. :: ..:
XP_011 LMAFPVTSIFHTFSRSYLELKQEQERVMFRRAQFLIKTKSQLSVSQDSDILFGSA--SSD
460 470 480 490 500
460
pF1KE5 SADALWVRAGR
. :
XP_011 TRDNN
510
>>XP_011527108 (OMIM: 603788) PREDICTED: potassium volta (513 aa)
initn: 1714 init1: 763 opt: 1286 Z-score: 1394.7 bits: 267.5 E(85289): 6e-71
Smith-Waterman score: 1728; 59.6% identity (80.6% similar) in 453 aa overlap (16-459:61-511)
10 20 30 40
pF1KE5 MEPWPCSPGGGGGGTRARHVIINVGGCRVRLAWAALARCPLARLE
: :..:::::: . : :..: . ::.::
XP_011 QRQAIKGAFYRRAQRLRPQDEPRQGCQPEDRRRRIIINVGGIKYSLPWTTLDEFPLTRLG
40 50 60 70 80 90
50 60 70 80 90 100
pF1KE5 RLRACRGHDDLLRVCDDYDVSRDEFFFDRSPCAFRAIVALLRAGKLRLLRGPCALAFRDE
.:.:: . ::.: :::::::. .::::::.: :: .:...:::::::::: :::.:..:
XP_011 QLKACTNFDDILNVCDDYDVTCNEFFFDRNPGAFGTILTFLRAGKLRLLREMCALSFQEE
100 110 120 130 140 150
110 120 130 140 150 160
pF1KE5 LAYWGIDEARLERCCLRRLRRREEEAAEARAGPTERGAQGSPAR-ALGP---RGRLQRGR
: :::: : .:. :: :: .. :: :: : : : .: . :: .::: :
XP_011 LLYWGIAEDHLDGCCKRRYLQKIEEFAEMVEREEEDDALDSEGRDSEGPAEGEGRLGRCM
160 170 180 190 200 210
170 180 190 200 210 220
pF1KE5 RRLRDVVDNPHSGLAGKLFACVSVSFVAVTAVGLCLSTMPDIRAEEERGECSPKCRSLFV
:::::.:. ::::: ::.:::.:: ::.::::.: .::.:..: :::.:.:: :...:.
XP_011 RRLRDMVERPHSGLPGKVFACLSVLFVTVTAVNLSVSTLPSLREEEEQGHCSQMCHNVFI
220 230 240 250 260 270
230 240 250 260 270
pF1KE5 LETVCVAWFSFEFLLRSLQAESKCAFLRAPLNIIDILALLPFYVSLLL-GLAAG---PG-
.:.:::.:::.::::: .:: :: ::::.::..::..:.::.:..::. : ::: ::
XP_011 VESVCVGWFSLEFLLRLIQAPSKFAFLRSPLTLIDLVAILPYYITLLVDGAAAGRRKPGA
280 290 300 310 320 330
280 290 300 310 320 330
pF1KE5 GTKLLERAGLVLRLLRALRVLYVMRLARHSLGLRSLGLTMRRCAREFGLLLLFLCVAMAL
:.. :...:::::.:::::.:::::::::::::..:::: :::.:::::::::::::.::
XP_011 GNSYLDKVGLVLRVLRALRILYVMRLARHSLGLQTLGLTARRCTREFGLLLLFLCVAIAL
340 350 360 370 380 390
340 350 360 370 380 390
pF1KE5 FAPLVHLAERELGARRDFSSVPASYWWAVISMTTVGYGDMVPRSLPGQVVALSSILSGIL
::::... : :.. .:.:.:: ::::::.::::::::::::: :::::::::::::::
XP_011 FAPLLYVIENEMADSPEFTSIPACYWWAVITMTTVGYGDMVPRSTPGQVVALSSILSGIL
400 410 420 430 440 450
400 410 420 430 440 450
pF1KE5 LMAFPVTSIFHTFSRSYSELKEQQQRAASPEPALQEDSTHSATATEDSSQGPDSAGLADD
::::::::::::::::: :::..:.:. . . . . ....::. :: ..:
XP_011 LMAFPVTSIFHTFSRSYLELKQEQERVMFRRAQFLIKTKSQLSVSQDSDILFGSA--SSD
460 470 480 490 500
460
pF1KE5 SADALWVRAGR
. :
XP_011 TRDNN
510
467 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 04:15:40 2016 done: Tue Nov 8 04:15:41 2016
Total Scan time: 8.100 Total Display time: 0.060
Function used was FASTA [36.3.4 Apr, 2011]