Result of FASTA (omim) for
pFN21AE5019
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5019, 350 aa
1>>>pF1KE5019 350 - 350 aa - 350 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.0192+/-0.00028; mu= 18.9091+/- 0.017
mean_var=75.0669+/-15.158, 0's: 0 Z-trim(120.1): 69 B-trim: 306 in 1/54
Lambda= 0.148030
statistics sampled from 34887 (34957) to 34887 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.772), E-opt: 0.2 (0.41), width: 16
Scan time: 7.990
The best scores are: opt bits E(85289)
NP_113667 (OMIM: 612031) inhibin beta E chain prep ( 350) 2448 531.5 1e-150
NP_005529 (OMIM: 601233) inhibin beta C chain prep ( 352) 823 184.5 3.1e-46
NP_002184 (OMIM: 147390) inhibin beta B chain prep ( 407) 552 126.6 9.1e-29
NP_002183 (OMIM: 147290) inhibin beta A chain prep ( 426) 500 115.6 2.1e-25
XP_016867665 (OMIM: 147290) PREDICTED: inhibin bet ( 426) 500 115.6 2.1e-25
XP_016867664 (OMIM: 147290) PREDICTED: inhibin bet ( 483) 500 115.6 2.3e-25
XP_016867663 (OMIM: 147290) PREDICTED: inhibin bet ( 548) 500 115.7 2.5e-25
XP_011527625 (OMIM: 112261,112600,235200) PREDICTE ( 240) 353 84.0 3.8e-16
NP_001191 (OMIM: 112261,112600,235200) bone morpho ( 396) 353 84.1 5.6e-16
NP_001483 (OMIM: 187500,208530,217095,602880,61385 ( 372) 342 81.8 2.7e-15
NP_878248 (OMIM: 604651) growth/differentiation fa ( 450) 333 79.9 1.2e-14
XP_016877094 (OMIM: 112262,600625,607932) PREDICTE ( 345) 321 77.3 5.7e-14
XP_016877093 (OMIM: 112262,600625,607932) PREDICTE ( 345) 321 77.3 5.7e-14
NP_570911 (OMIM: 112262,600625,607932) bone morpho ( 408) 321 77.3 6.5e-14
XP_005268072 (OMIM: 112262,600625,607932) PREDICTE ( 408) 321 77.3 6.5e-14
NP_001193 (OMIM: 112262,600625,607932) bone morpho ( 408) 321 77.3 6.5e-14
XP_016877092 (OMIM: 112262,600625,607932) PREDICTE ( 408) 321 77.3 6.5e-14
NP_001709 (OMIM: 112266) bone morphogenetic protei ( 513) 319 77.0 1e-13
NP_001001557 (OMIM: 118100,601147,613094,613703,61 ( 455) 315 76.1 1.7e-13
NP_001710 (OMIM: 112267) bone morphogenetic protei ( 431) 306 74.1 6.2e-13
NP_065685 (OMIM: 606522,613702,613703,613704) grow ( 364) 305 73.9 6.4e-13
NP_001316868 (OMIM: 107970,190230,615582) transfor ( 412) 303 73.5 9.4e-13
NP_003230 (OMIM: 107970,190230,615582) transformin ( 412) 303 73.5 9.4e-13
NP_001306067 (OMIM: 112600,113100,200700,201250,22 ( 501) 300 72.9 1.7e-12
NP_000548 (OMIM: 112600,113100,200700,201250,22890 ( 501) 300 72.9 1.7e-12
XP_011527377 (OMIM: 112600,113100,200700,201250,22 ( 501) 300 72.9 1.7e-12
NP_000651 (OMIM: 131300,190180,219700) transformin ( 390) 290 70.7 6.2e-12
NP_001711 (OMIM: 602284) bone morphogenetic protei ( 402) 289 70.5 7.3e-12
XP_011540326 (OMIM: 602284) PREDICTED: bone morpho ( 427) 289 70.5 7.6e-12
XP_016866687 (OMIM: 112265) PREDICTED: bone morpho ( 239) 286 69.6 7.7e-12
NP_001192 (OMIM: 112263) bone morphogenetic protei ( 472) 289 70.5 8.2e-12
NP_001316835 (OMIM: 270100,601265) nodal homolog i ( 214) 285 69.4 8.3e-12
NP_060525 (OMIM: 270100,601265) nodal homolog isof ( 347) 285 69.6 1.2e-11
NP_066551 (OMIM: 112265) bone morphogenetic protei ( 454) 286 69.9 1.2e-11
XP_011525544 (OMIM: 131300,190180,219700) PREDICTE ( 391) 285 69.6 1.3e-11
NP_055297 (OMIM: 608748) bone morphogenetic protei ( 424) 282 69.0 2.1e-11
NP_003229 (OMIM: 190220,614816) transforming growt ( 414) 271 66.6 1.1e-10
NP_001129071 (OMIM: 190220,614816) transforming gr ( 442) 271 66.7 1.1e-10
NP_004953 (OMIM: 601361) growth/differentiation fa ( 478) 270 66.5 1.4e-10
NP_004855 (OMIM: 605312) growth/differentiation fa ( 308) 266 65.5 1.8e-10
NP_002182 (OMIM: 147380) inhibin alpha chain prepr ( 366) 246 61.3 4e-09
NP_057288 (OMIM: 605120,615506) growth/differentia ( 429) 238 59.6 1.5e-08
XP_011541613 (OMIM: 601918) PREDICTED: growth/diff ( 276) 233 58.4 2.2e-08
NP_001275757 (OMIM: 601918) growth/differentiation ( 366) 233 58.5 2.7e-08
NP_001275755 (OMIM: 601918) growth/differentiation ( 366) 233 58.5 2.7e-08
XP_006714648 (OMIM: 601918) PREDICTED: growth/diff ( 366) 233 58.5 2.7e-08
NP_001275753 (OMIM: 601918) growth/differentiation ( 366) 233 58.5 2.7e-08
XP_005272014 (OMIM: 601918) PREDICTED: growth/diff ( 366) 233 58.5 2.7e-08
XP_011541612 (OMIM: 601918) PREDICTED: growth/diff ( 366) 233 58.5 2.7e-08
NP_001275754 (OMIM: 601918) growth/differentiation ( 366) 233 58.5 2.7e-08
>>NP_113667 (OMIM: 612031) inhibin beta E chain prepropr (350 aa)
initn: 2448 init1: 2448 opt: 2448 Z-score: 2826.6 bits: 531.5 E(85289): 1e-150
Smith-Waterman score: 2448; 100.0% identity (100.0% similar) in 350 aa overlap (1-350:1-350)
10 20 30 40 50 60
pF1KE5 MRLPDVQLWLVLLWALVRAQGTGSVCPSCGGSKLAPQAERALVLELAKQQILDGLHLTSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_113 MRLPDVQLWLVLLWALVRAQGTGSVCPSCGGSKLAPQAERALVLELAKQQILDGLHLTSR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 PRITHPPPQAALTRALRRLQPGSVAPGNGEEVISFATVTDSTSAYSSLLTFHLSTPRSHH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_113 PRITHPPPQAALTRALRRLQPGSVAPGNGEEVISFATVTDSTSAYSSLLTFHLSTPRSHH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 LYHARLWLHVLPTLPGTLCLRIFRWGPRRRRQGSRTLLAEHHITNLGWHTLTLPSSGLRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_113 LYHARLWLHVLPTLPGTLCLRIFRWGPRRRRQGSRTLLAEHHITNLGWHTLTLPSSGLRG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 EKSGVLKLQLDCRPLEGNSTVTGQPRRLLDTAGHQQPFLELKIRANEPGAGRARRRTPTC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_113 EKSGVLKLQLDCRPLEGNSTVTGQPRRLLDTAGHQQPFLELKIRANEPGAGRARRRTPTC
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 EPATPLCCRRDHYVDFQELGWRDWILQPEGYQLNYCSGQCPPHLAGSPGIAASFHSAVFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_113 EPATPLCCRRDHYVDFQELGWRDWILQPEGYQLNYCSGQCPPHLAGSPGIAASFHSAVFS
250 260 270 280 290 300
310 320 330 340 350
pF1KE5 LLKANNPWPASTSCCVPTARRPLSLLYLDHNGNVVKTDVPDMVVEACGCS
::::::::::::::::::::::::::::::::::::::::::::::::::
NP_113 LLKANNPWPASTSCCVPTARRPLSLLYLDHNGNVVKTDVPDMVVEACGCS
310 320 330 340 350
>>NP_005529 (OMIM: 601233) inhibin beta C chain prepropr (352 aa)
initn: 614 init1: 387 opt: 823 Z-score: 951.1 bits: 184.5 E(85289): 3.1e-46
Smith-Waterman score: 887; 43.3% identity (69.0% similar) in 358 aa overlap (9-350:9-352)
10 20 30 40 50 60
pF1KE5 MRLPDVQLWLVLLWALVRAQGTGSVCPSCGGSKLAPQAERALVLELAKQQILDGLHLTSR
.:.: . : . .:. ::.::: : ...: :.:.:::..::: ::::.:
NP_005 MTSSLLLAFLLLAPTTVATPRAGGQCPACGGPTLELESQRELLLDLAKRSILDKLHLTQR
10 20 30 40 50 60
70 80 90 100 110
pF1KE5 PRITHPPPQAALTRALRRLQ--P-GSVAPGNGE---EVISFATVTDSTSAYSSLLTFHLS
: ...: .::: ::..:. : :.. : : :.:::: : .. .. : ::.:
NP_005 PTLNRPVSRAALRTALQHLHGVPQGALLEDNREQECEIISFAE-TGLSTINQTRLDFHFS
70 80 90 100 110
120 130 140 150 160
pF1KE5 TPRS---HHLYHARLWLHV-LPT-LPGTLCLRIFRWGPRRRRQGSRTLLAEHHITNL---
. :. ... .: : . : ::. :: .:.. :: ... :: ... ..
NP_005 SDRTAGDREVQQASLMFFVQLPSNTTWTLKVRVLVLGP----HNTNLTLATQYLLEVDAS
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE5 GWHTLTLPSSGLRGEKSGVLKLQLDCRPLEGNSTVTGQPRRLLDTAGHQQPFLELKIRAN
::: : : . . ..: : :.: :::. ..: .: :.:. ::. ..:..
NP_005 GWHQLPLGPEAQAACSQGHLTLEL---VLEGQ---VAQSSVILGGAAHR-PFVAARVRVG
180 190 200 210 220
230 240 250 260 270 280
pF1KE5 EPGAGRARRRTPTCEPATPLCCRRDHYVDFQELGWRDWILQPEGYQLNYCSGQCPPHLAG
: . .:: :. .. .:::.. .:::.:.::.:::.::::: .:.: :::: :.::
NP_005 --GKHQIHRRGIDCQGGSRMCCRQEFFVDFREIGWHDWIIQPEGYAMNFCIGQCPLHIAG
230 240 250 260 270 280
290 300 310 320 330 340
pF1KE5 SPGIAASFHSAVFSLLKANNPWPAST--SCCVPTARRPLSLLYLDHNGNVVKTDVPDMVV
::::::::.::..:::::. .. ::::::::::::::: :...:.::::.:::::
NP_005 MPGIAASFHTAVLNLLKANTAAGTTGGGSCCVPTARRPLSLLYYDRDSNIVKTDIPDMVV
290 300 310 320 330 340
350
pF1KE5 EACGCS
::::::
NP_005 EACGCS
350
>>NP_002184 (OMIM: 147390) inhibin beta B chain prepropr (407 aa)
initn: 657 init1: 278 opt: 552 Z-score: 637.4 bits: 126.6 E(85289): 9.1e-29
Smith-Waterman score: 668; 36.2% identity (59.9% similar) in 367 aa overlap (21-350:50-407)
10 20 30 40
pF1KE5 MRLPDVQLWLVLLWALVRAQGTGSVCPSCGGSKLAPQAERAL--VLELAK
:. ..: :::: . . :. :: .:
NP_002 GWLGPEAWGSPTPPPTPAAPPPPPPPGSPGGSQDTCTSCGGFRRPEELGRVDGDFLEAVK
20 30 40 50 60 70
50 60 70 80 90
pF1KE5 QQILDGLHLTSRPRITHPPPQAALTRALRRLQPGSV---------------APG-NGEE-
..::. :.. .:: ::: :.::.. :::.:. :.: .:: .:.:
NP_002 RHILSRLQMRGRPNITHAVPKAAMVTALRKLHAGKVREDGRVEIPHLDGHASPGADGQER
80 90 100 110 120 130
100 110 120 130 140
pF1KE5 ---VISFATVTDSTSAYSSLLTFHLSTPRSHHLY--HARLWLHVLPTLPGTL---CLRIF
.:::: ::. .. : : .:. ...:. .: :::. : :: .: :
NP_002 VSEIISFAE-TDGLASSRVRLYFFISNEGNQNLFVVQASLWLY-LKLLPYVLEKGSRRKV
140 150 160 170 180 190
150 160 170 180 190
pF1KE5 RWGPRRRRQG--SRTLLAEHHIT--NLGWHTLTLPSS--GL--RGEKSGVLKLQLD-CRP
: ..:: .: ..:... ::::. : . .: :::. : .: : :.
NP_002 RVKVYFQEQGHGDRWNMVEKRVDLKRSGWHTFPLTEAIQALFERGERRLNLDVQCDSCQE
200 210 220 230 240 250
200 210 220 230 240 250
pF1KE5 LEGNSTVTGQPRRLLDTAGHQQPFLELKIRANEPGAGRARRRTPTCEPATPLCCRRDHYV
: . : .: .:. ::. .. : .. . : :.: :. : ::::.. ..
NP_002 L-AVVPVFVDP----GEESHR-PFVVVQARLGD-SRHRIRKRGLECDGRTNLCCRQQFFI
260 270 280 290 300 310
260 270 280 290 300 310
pF1KE5 DFQELGWRDWILQPEGYQLNYCSGQCPPHLAGSPGIAASFHSAVFSLLKANNPWPAST-S
::. .:: :::. : :: ::: :.:: .::: :: :.:::.:: . . . :... :
NP_002 DFRLIGWNDWIIAPTGYYGNYCEGSCPAYLAGVPGSASSFHTAVVNQYRMRGLNPGTVNS
320 330 340 350 360 370
320 330 340 350
pF1KE5 CCVPTARRPLSLLYLDHNGNVVKTDVPDMVVEACGCS
::.:: .:.::.: . :.:: :::.:.:: :::.
NP_002 CCIPTKLSTMSMLYFDDEYNIVKRDVPNMIVEECGCA
380 390 400
>>NP_002183 (OMIM: 147290) inhibin beta A chain prepropr (426 aa)
initn: 661 init1: 317 opt: 500 Z-score: 577.1 bits: 115.6 E(85289): 2.1e-25
Smith-Waterman score: 578; 31.0% identity (56.0% similar) in 384 aa overlap (33-350:45-426)
10 20 30 40 50 60
pF1KE5 LPDVQLWLVLLWALVRAQGTGSVCPSCGGSKLAPQAERALVLELAKQQILDGLHLTSRPR
: .:... .: : .:..::. ::: .::
NP_002 WIIVRSSPTPGSEGHSAAPDCPSCALAALPKDVPNSQPEMV-EAVKKHILNMLHLKKRPD
20 30 40 50 60 70
70 80 90 100 110
pF1KE5 ITHPPPQAALTRALRRLQPGSVAPGNG-----EEVISFATVTDSTSAYSSLLTFHLSTPR
.:.: :.::: :.:.:. :.:. :: ... : ... : ..:: :
NP_002 VTQPVPKAALLNAIRKLHVGKVGE-NGYVEIEDDIGRRAEMNELMEQTSEIITFAESGTA
80 90 100 110 120 130
120 130 140
pF1KE5 SHHLY--------------HARLWLHV-LPTLPGT---LCLRIFRW----------GPRR
. :. .:..:: . .: : . .:.:. : .
NP_002 RKTLHFEISKEGSDLSVVERAEVWLFLKVPKANRTRTKVTIRLFQQQKHPQGSLDTGEEA
140 150 160 170 180 190
150 160 170 180 190
pF1KE5 RRQG-----SRTLLAEHHIT--NLGWHTLTLPSSGLRGEKSG--VLKLQLDCRPLE--GN
.. : :. ::.:. . . ::.. . :: : .: : ... :. . :
NP_002 EEVGLKGERSELLLSEKVVDARKSTWHVFPVSSSIQRLLDQGKSSLDVRIACEQCQESGA
200 210 220 230 240 250
200 210 220 230
pF1KE5 STVT-GQPRRLLDT------------AG-------HQQPFLELKIRANEPGAGRARRRTP
: : :. .. . :: ..::: :. : .: : :::
NP_002 SLVLLGKKKKKEEEGEGKKKGGGEGGAGADEEKEQSHRPFLMLQARQSEDHPHRRRRRGL
260 270 280 290 300 310
240 250 260 270 280 290
pF1KE5 TCEPATPLCCRRDHYVDFQELGWRDWILQPEGYQLNYCSGQCPPHLAGSPGIAASFHSAV
:. . .::... .:.:...:: :::. : ::. ::: :.:: :.::. : . ::::.:
NP_002 ECDGKVNICCKKQFFVSFKDIGWNDWIIAPSGYHANYCEGECPSHIAGTSGSSLSFHSTV
320 330 340 350 360 370
300 310 320 330 340 350
pF1KE5 FSL--LKANNPWPASTSCCVPTARRPLSLLYLDHNGNVVKTDVPDMVVEACGCS
.. .....:. :::::: ::.:.:: : . :..: :. .:.:: ::::
NP_002 INHYRMRGHSPFANLKSCCVPTKLRPMSMLYYDDGQNIIKKDIQNMIVEECGCS
380 390 400 410 420
>>XP_016867665 (OMIM: 147290) PREDICTED: inhibin beta A (426 aa)
initn: 661 init1: 317 opt: 500 Z-score: 577.1 bits: 115.6 E(85289): 2.1e-25
Smith-Waterman score: 578; 31.0% identity (56.0% similar) in 384 aa overlap (33-350:45-426)
10 20 30 40 50 60
pF1KE5 LPDVQLWLVLLWALVRAQGTGSVCPSCGGSKLAPQAERALVLELAKQQILDGLHLTSRPR
: .:... .: : .:..::. ::: .::
XP_016 WIIVRSSPTPGSEGHSAAPDCPSCALAALPKDVPNSQPEMV-EAVKKHILNMLHLKKRPD
20 30 40 50 60 70
70 80 90 100 110
pF1KE5 ITHPPPQAALTRALRRLQPGSVAPGNG-----EEVISFATVTDSTSAYSSLLTFHLSTPR
.:.: :.::: :.:.:. :.:. :: ... : ... : ..:: :
XP_016 VTQPVPKAALLNAIRKLHVGKVGE-NGYVEIEDDIGRRAEMNELMEQTSEIITFAESGTA
80 90 100 110 120 130
120 130 140
pF1KE5 SHHLY--------------HARLWLHV-LPTLPGT---LCLRIFRW----------GPRR
. :. .:..:: . .: : . .:.:. : .
XP_016 RKTLHFEISKEGSDLSVVERAEVWLFLKVPKANRTRTKVTIRLFQQQKHPQGSLDTGEEA
140 150 160 170 180 190
150 160 170 180 190
pF1KE5 RRQG-----SRTLLAEHHIT--NLGWHTLTLPSSGLRGEKSG--VLKLQLDCRPLE--GN
.. : :. ::.:. . . ::.. . :: : .: : ... :. . :
XP_016 EEVGLKGERSELLLSEKVVDARKSTWHVFPVSSSIQRLLDQGKSSLDVRIACEQCQESGA
200 210 220 230 240 250
200 210 220 230
pF1KE5 STVT-GQPRRLLDT------------AG-------HQQPFLELKIRANEPGAGRARRRTP
: : :. .. . :: ..::: :. : .: : :::
XP_016 SLVLLGKKKKKEEEGEGKKKGGGEGGAGADEEKEQSHRPFLMLQARQSEDHPHRRRRRGL
260 270 280 290 300 310
240 250 260 270 280 290
pF1KE5 TCEPATPLCCRRDHYVDFQELGWRDWILQPEGYQLNYCSGQCPPHLAGSPGIAASFHSAV
:. . .::... .:.:...:: :::. : ::. ::: :.:: :.::. : . ::::.:
XP_016 ECDGKVNICCKKQFFVSFKDIGWNDWIIAPSGYHANYCEGECPSHIAGTSGSSLSFHSTV
320 330 340 350 360 370
300 310 320 330 340 350
pF1KE5 FSL--LKANNPWPASTSCCVPTARRPLSLLYLDHNGNVVKTDVPDMVVEACGCS
.. .....:. :::::: ::.:.:: : . :..: :. .:.:: ::::
XP_016 INHYRMRGHSPFANLKSCCVPTKLRPMSMLYYDDGQNIIKKDIQNMIVEECGCS
380 390 400 410 420
>>XP_016867664 (OMIM: 147290) PREDICTED: inhibin beta A (483 aa)
initn: 661 init1: 317 opt: 500 Z-score: 576.4 bits: 115.6 E(85289): 2.3e-25
Smith-Waterman score: 578; 31.0% identity (56.0% similar) in 384 aa overlap (33-350:102-483)
10 20 30 40 50 60
pF1KE5 LPDVQLWLVLLWALVRAQGTGSVCPSCGGSKLAPQAERALVLELAKQQILDGLHLTSRPR
: .:... .: : .:..::. ::: .::
XP_016 WIIVRSSPTPGSEGHSAAPDCPSCALAALPKDVPNSQPEMV-EAVKKHILNMLHLKKRPD
80 90 100 110 120 130
70 80 90 100 110
pF1KE5 ITHPPPQAALTRALRRLQPGSVAPGNG-----EEVISFATVTDSTSAYSSLLTFHLSTPR
.:.: :.::: :.:.:. :.:. :: ... : ... : ..:: :
XP_016 VTQPVPKAALLNAIRKLHVGKVGE-NGYVEIEDDIGRRAEMNELMEQTSEIITFAESGTA
140 150 160 170 180
120 130 140
pF1KE5 SHHLY--------------HARLWLHV-LPTLPGT---LCLRIFRW----------GPRR
. :. .:..:: . .: : . .:.:. : .
XP_016 RKTLHFEISKEGSDLSVVERAEVWLFLKVPKANRTRTKVTIRLFQQQKHPQGSLDTGEEA
190 200 210 220 230 240
150 160 170 180 190
pF1KE5 RRQG-----SRTLLAEHHIT--NLGWHTLTLPSSGLRGEKSG--VLKLQLDCRPLE--GN
.. : :. ::.:. . . ::.. . :: : .: : ... :. . :
XP_016 EEVGLKGERSELLLSEKVVDARKSTWHVFPVSSSIQRLLDQGKSSLDVRIACEQCQESGA
250 260 270 280 290 300
200 210 220 230
pF1KE5 STVT-GQPRRLLDT------------AG-------HQQPFLELKIRANEPGAGRARRRTP
: : :. .. . :: ..::: :. : .: : :::
XP_016 SLVLLGKKKKKEEEGEGKKKGGGEGGAGADEEKEQSHRPFLMLQARQSEDHPHRRRRRGL
310 320 330 340 350 360
240 250 260 270 280 290
pF1KE5 TCEPATPLCCRRDHYVDFQELGWRDWILQPEGYQLNYCSGQCPPHLAGSPGIAASFHSAV
:. . .::... .:.:...:: :::. : ::. ::: :.:: :.::. : . ::::.:
XP_016 ECDGKVNICCKKQFFVSFKDIGWNDWIIAPSGYHANYCEGECPSHIAGTSGSSLSFHSTV
370 380 390 400 410 420
300 310 320 330 340 350
pF1KE5 FSL--LKANNPWPASTSCCVPTARRPLSLLYLDHNGNVVKTDVPDMVVEACGCS
.. .....:. :::::: ::.:.:: : . :..: :. .:.:: ::::
XP_016 INHYRMRGHSPFANLKSCCVPTKLRPMSMLYYDDGQNIIKKDIQNMIVEECGCS
430 440 450 460 470 480
>>XP_016867663 (OMIM: 147290) PREDICTED: inhibin beta A (548 aa)
initn: 661 init1: 317 opt: 500 Z-score: 575.7 bits: 115.7 E(85289): 2.5e-25
Smith-Waterman score: 578; 31.0% identity (56.0% similar) in 384 aa overlap (33-350:167-548)
10 20 30 40 50 60
pF1KE5 LPDVQLWLVLLWALVRAQGTGSVCPSCGGSKLAPQAERALVLELAKQQILDGLHLTSRPR
: .:... .: : .:..::. ::: .::
XP_016 WIIVRSSPTPGSEGHSAAPDCPSCALAALPKDVPNSQPEMV-EAVKKHILNMLHLKKRPD
140 150 160 170 180 190
70 80 90 100 110
pF1KE5 ITHPPPQAALTRALRRLQPGSVAPGNG-----EEVISFATVTDSTSAYSSLLTFHLSTPR
.:.: :.::: :.:.:. :.:. :: ... : ... : ..:: :
XP_016 VTQPVPKAALLNAIRKLHVGKVGE-NGYVEIEDDIGRRAEMNELMEQTSEIITFAESGTA
200 210 220 230 240 250
120 130 140
pF1KE5 SHHLY--------------HARLWLHV-LPTLPGT---LCLRIFRW----------GPRR
. :. .:..:: . .: : . .:.:. : .
XP_016 RKTLHFEISKEGSDLSVVERAEVWLFLKVPKANRTRTKVTIRLFQQQKHPQGSLDTGEEA
260 270 280 290 300 310
150 160 170 180 190
pF1KE5 RRQG-----SRTLLAEHHIT--NLGWHTLTLPSSGLRGEKSG--VLKLQLDCRPLE--GN
.. : :. ::.:. . . ::.. . :: : .: : ... :. . :
XP_016 EEVGLKGERSELLLSEKVVDARKSTWHVFPVSSSIQRLLDQGKSSLDVRIACEQCQESGA
320 330 340 350 360 370
200 210 220 230
pF1KE5 STVT-GQPRRLLDT------------AG-------HQQPFLELKIRANEPGAGRARRRTP
: : :. .. . :: ..::: :. : .: : :::
XP_016 SLVLLGKKKKKEEEGEGKKKGGGEGGAGADEEKEQSHRPFLMLQARQSEDHPHRRRRRGL
380 390 400 410 420 430
240 250 260 270 280 290
pF1KE5 TCEPATPLCCRRDHYVDFQELGWRDWILQPEGYQLNYCSGQCPPHLAGSPGIAASFHSAV
:. . .::... .:.:...:: :::. : ::. ::: :.:: :.::. : . ::::.:
XP_016 ECDGKVNICCKKQFFVSFKDIGWNDWIIAPSGYHANYCEGECPSHIAGTSGSSLSFHSTV
440 450 460 470 480 490
300 310 320 330 340 350
pF1KE5 FSL--LKANNPWPASTSCCVPTARRPLSLLYLDHNGNVVKTDVPDMVVEACGCS
.. .....:. :::::: ::.:.:: : . :..: :. .:.:: ::::
XP_016 INHYRMRGHSPFANLKSCCVPTKLRPMSMLYYDDGQNIIKKDIQNMIVEECGCS
500 510 520 530 540
>>XP_011527625 (OMIM: 112261,112600,235200) PREDICTED: b (240 aa)
initn: 310 init1: 172 opt: 353 Z-score: 410.8 bits: 84.0 E(85289): 3.8e-16
Smith-Waterman score: 353; 37.6% identity (58.8% similar) in 170 aa overlap (181-349:79-239)
160 170 180 190 200
pF1KE5 RQGSRTLLAEHHITNLGWHTLTLPSSGLRGEKSGVLKLQLD-CRPLEGNSTVTGQPRRLL
::.:: : .. : :. . .: : ::
XP_011 ESFDVTPAVMRWTAQGHANHGFVVEVAHLEEKQGVSKRHVRISRSLHQDEHSWSQIRPLL
50 60 70 80 90 100
210 220 230 240 250 260
pF1KE5 DTAGHQQPFLELKIRANEPGAGRARRRTPTCEPATPLCCRRDHYVDFQELGWRDWILQPE
: ::. :. : .. . . :.: . : :. ::::...:: :::. :
XP_011 VTFGHDGKGHPLHKREKRQAKHKQRKRLKSS------CKRHPLYVDFSDVGWNDWIVAPP
110 120 130 140 150 160
270 280 290 300 310 320
pF1KE5 GYQLNYCSGQCPPHLAGSPGIAASFHSAVFSLLKANNPWPASTSCCVPTARRPLSLLYLD
::. :: :.:: :: . .. :. : .:... : .::::: .:.::::
XP_011 GYHAFYCHGECPFPLADH--LNSTNHAIVQTLVNSVNS-KIPKACCVPTELSAISMLYLD
170 180 190 200 210
330 340 350
pF1KE5 HNGNVVKTDVPDMVVEACGCS
.: .:: . :::::.:::
XP_011 ENEKVVLKNYQDMVVEGCGCR
220 230 240
>>NP_001191 (OMIM: 112261,112600,235200) bone morphogene (396 aa)
initn: 338 init1: 172 opt: 353 Z-score: 407.9 bits: 84.1 E(85289): 5.6e-16
Smith-Waterman score: 353; 37.6% identity (58.8% similar) in 170 aa overlap (181-349:235-395)
160 170 180 190 200
pF1KE5 RQGSRTLLAEHHITNLGWHTLTLPSSGLRGEKSGVLKLQLD-CRPLEGNSTVTGQPRRLL
::.:: : .. : :. . .: : ::
NP_001 ESFDVTPAVMRWTAQGHANHGFVVEVAHLEEKQGVSKRHVRISRSLHQDEHSWSQIRPLL
210 220 230 240 250 260
210 220 230 240 250 260
pF1KE5 DTAGHQQPFLELKIRANEPGAGRARRRTPTCEPATPLCCRRDHYVDFQELGWRDWILQPE
: ::. :. : .. . . :.: . : :. ::::...:: :::. :
NP_001 VTFGHDGKGHPLHKREKRQAKHKQRKRLKSS------CKRHPLYVDFSDVGWNDWIVAPP
270 280 290 300 310
270 280 290 300 310 320
pF1KE5 GYQLNYCSGQCPPHLAGSPGIAASFHSAVFSLLKANNPWPASTSCCVPTARRPLSLLYLD
::. :: :.:: :: . .. :. : .:... : .::::: .:.::::
NP_001 GYHAFYCHGECPFPLADH--LNSTNHAIVQTLVNSVNS-KIPKACCVPTELSAISMLYLD
320 330 340 350 360 370
330 340 350
pF1KE5 HNGNVVKTDVPDMVVEACGCS
.: .:: . :::::.:::
NP_001 ENEKVVLKNYQDMVVEGCGCR
380 390
>>NP_001483 (OMIM: 187500,208530,217095,602880,613854) e (372 aa)
initn: 372 init1: 192 opt: 342 Z-score: 395.6 bits: 81.8 E(85289): 2.7e-15
Smith-Waterman score: 342; 40.4% identity (63.2% similar) in 136 aa overlap (218-349:237-371)
190 200 210 220 230 240
pF1KE5 LQLDCRPLEGNSTVTGQPRRLLDTAGHQQPFLELKIRANEPGAGRARRRTPTCEPATPL-
.. : : .: : : :: . . :
NP_001 ASWPRSLRLALALRPRAPAACARLAEASLLLVTLDPRLCHPLA-RPRRDAEPVLGGGPGG
210 220 230 240 250 260
250 260 270 280 290 300
pF1KE5 CCR-RDHYVDFQELGWRDWILQPEGYQLNYCSGQC--PPHLAGSPGIAASFHSAVFSLLK
:: : ::.:.:.::. :.. :.:. :::.::: : :.:: : : :... .:..
NP_001 ACRARRLYVSFREVGWHRWVIAPRGFLANYCQGQCALPVALSGSGGPPALNHAVLRALMH
270 280 290 300 310 320
310 320 330 340 350
pF1KE5 ANNPWPASTSCCVPTARRPLSLLYLDHNGNVVKTDVPDMVVEACGCS
: : :. ::::. :.:.:..:.. ::: . ::::. :::
NP_001 AAAPGAADLPCCVPARLSPISVLFFDNSDNVVLRQYEDMVVDECGCR
330 340 350 360 370
350 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 04:13:06 2016 done: Tue Nov 8 04:13:07 2016
Total Scan time: 7.990 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]