Result of FASTA (ccds) for
pFN21AE5016
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5016, 334 aa
1>>>pF1KE5016 334 - 334 aa - 334 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.6422+/-0.000731; mu= 12.7620+/- 0.044
mean_var=160.5121+/-32.650, 0's: 0 Z-trim(116.1): 153 B-trim: 10 in 1/51
Lambda= 0.101233
statistics sampled from 16522 (16699) to 16522 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.811), E-opt: 0.2 (0.513), width: 16
Scan time: 3.380
The best scores are: opt bits E(32554)
CCDS35184.1 LRRC26 gene_id:389816|Hs108|chr9 ( 334) 2286 344.9 5.3e-95
CCDS53269.1 LRRC38 gene_id:126755|Hs108|chr1 ( 294) 464 78.8 6.2e-15
CCDS31539.1 LRRC55 gene_id:219527|Hs108|chr11 ( 341) 453 77.2 2.1e-14
CCDS7453.1 SLIT1 gene_id:6585|Hs108|chr10 (1534) 419 73.0 1.8e-12
CCDS10259.1 ISLR2 gene_id:57611|Hs108|chr15 ( 745) 399 69.7 8.4e-12
CCDS31726.1 LRTM2 gene_id:654429|Hs108|chr12 ( 370) 390 68.1 1.3e-11
>>CCDS35184.1 LRRC26 gene_id:389816|Hs108|chr9 (334 aa)
initn: 2286 init1: 2286 opt: 2286 Z-score: 1819.0 bits: 344.9 E(32554): 5.3e-95
Smith-Waterman score: 2286; 99.4% identity (99.7% similar) in 334 aa overlap (1-334:1-334)
10 20 30 40 50 60
pF1KE5 MRGPSWLRPRPLLLLLLLLSPWPVWAHVSATASPSGSLGAPDCPEVCTCVPGGLASCSAL
:::::: :::::::::::::::::::.:::::::::::::::::::::::::::::::::
CCDS35 MRGPSWSRPRPLLLLLLLLSPWPVWAQVSATASPSGSLGAPDCPEVCTCVPGGLASCSAL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 SLPAVPPGLSLRLRALLLDHNRVRALPPGAFAGAGALQRLDLRENGLHSVHVRAFWGLGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS35 SLPAVPPGLSLRLRALLLDHNRVRALPPGAFAGAGALQRLDLRENGLHSVHVRAFWGLGA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 LQLLDLSANQLEALAPGTFAPLRALRNLSLAGNRLARLEPAALGALPLLRSLSLQDNELA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS35 LQLLDLSANQLEALAPGTFAPLRALRNLSLAGNRLARLEPAALGALPLLRSLSLQDNELA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 ALAPGLLGRLPALDALHLRGNPWGCGCALRPLCAWLRRHPLPASEAETVLCVWPGRLTLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS35 ALAPGLLGRLPALDALHLRGNPWGCGCALRPLCAWLRRHPLPASEAETVLCVWPGRLTLS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 PLTAFSDAAFSHCAQPLALRDLAVVYTLGPASFLVSLASCLALGSGLTACRARRRRLRTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS35 PLTAFSDAAFSHCAQPLALRDLAVVYTLGPASFLVSLASCLALGSGLTACRARRRRLRTA
250 260 270 280 290 300
310 320 330
pF1KE5 ALRPPRPPDPNPDPDPHGCASPADPGSPAAAAQA
::::::::::::::::::::::::::::::::::
CCDS35 ALRPPRPPDPNPDPDPHGCASPADPGSPAAAAQA
310 320 330
>>CCDS53269.1 LRRC38 gene_id:126755|Hs108|chr1 (294 aa)
initn: 547 init1: 368 opt: 464 Z-score: 381.6 bits: 78.8 E(32554): 6.2e-15
Smith-Waterman score: 464; 35.4% identity (60.4% similar) in 260 aa overlap (38-293:21-278)
10 20 30 40 50 60
pF1KE5 RPRPLLLLLLLLSPWPVWAHVSATASPSGSLGAPD--CPEVCTCVPGGLASCSALSLPAV
: :: :: :.:. ..: .::.:
CCDS53 MRPRAPACAAAALGLCSLLLLLAPGHACPAGCACTDPHTVDCRDRGLPSV
10 20 30 40 50
70 80 90 100 110 120
pF1KE5 PPGLSLRLRALLLDHNRVRALPPGAFAGAGALQRLDLRENGLHSVHVRAFWGLGALQLLD
: . : .: ::. ::.. .: : : : ::.:.:.:.:.. .: : . : .::
CCDS53 PDPFPLDVRKLLVAGNRIQRIPEDFFIFYGDLVYLDFRNNSLRSLEEGTFSGSAKLVFLD
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE5 LSANQLEALAPGTFAPLRALRNLSLAGNRLARLEPAALGALPLLRSLSLQDNELAALAPG
:: :.: :. :.: : .::::.: :. .. :. .: :. : :.::.: .:. .
CCDS53 LSYNNLTQLGAGAFRSAGRLVKLSLANNNLVGVHEDAFETLESLQVLELNDNNLRSLSVA
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE5 LLGRLPALDALHLRGNPWGCGCALRPLCAWLRRHP--LPASEAETVLCVWPGRLTLSPLT
:. :::: .:.: :::: : : . : .:.... :: . : . : : . :
CCDS53 ALAALPALRSLRLDGNPWLCDCDFAHLFSWIQENASKLPKGLDE-IQCSLPMESRRISLR
180 190 200 210 220
250 260 270 280 290 300
pF1KE5 AFSDAAFSHCAQPLALRDLAVVYTLGPASFLVSLASCLALGSGLTACRARRRRLRTAALR
.:.:.::.: :.: :: .. : : .... : . :.. .. : :
CCDS53 ELSEASFSECRFSLSLTDLCIIIFSGVAVSIAAIISSFFLAT-VVQCLQRCAPNKDAEDE
230 240 250 260 270 280
310 320 330
pF1KE5 PPRPPDPNPDPDPHGCASPADPGSPAAAAQA
CCDS53 DEDKDD
290
>>CCDS31539.1 LRRC55 gene_id:219527|Hs108|chr11 (341 aa)
initn: 355 init1: 179 opt: 453 Z-score: 372.1 bits: 77.2 E(32554): 2.1e-14
Smith-Waterman score: 455; 32.4% identity (57.4% similar) in 296 aa overlap (3-290:45-329)
10 20
pF1KE5 MRGPSWLR------PRPLLLLLLLLSPWPVWA
: .: . :.: .::. :: .
CCDS31 SCLPVSQTLDSMDTVLMGSLQHCCCLLPKMGDTWAQLPWPGPPHPAMLLISLLLAAGLM-
20 30 40 50 60 70
30 40 50 60 70 80
pF1KE5 HVSATASPSGSLGAPDCPEVCTCVPGGLASCSALSLPAVPPGLSLRLRALLLDHNRVRAL
: .: .: :: .::: . ...::. : .::: : . : : : :::. :.
CCDS31 HSDAGTS---------CPVLCTCR-NQVVDCSSQRLFSVPPDLPMDTRNLSLAHNRITAV
80 90 100 110 120
90 100 110 120 130 140
pF1KE5 PPGAFAGAGALQRLDLRENGLHSVHVRAFWGLGALQLLDLSANQLEALAPGTFAPLRALR
::: .. :: :::..:.: . : : :::: :.. . : ..:
CCDS31 PPGYLTCYMELQVLDLHNNSLMELPRGLFLHAKRLAHLDLSYNNFSHVPADMFQEAHGLV
130 140 150 160 170 180
150 160 170 180 190 200
pF1KE5 NLSLAGNR-LARLEPAALGALPLLRSLSLQDNELAALAPGLLGRLPALDALHLRGNPWGC
...:. : : :..: :. .: ::.:.:. . :: :. : ::.: .:.. :::: :
CCDS31 HIDLSHNPWLRRVHPQAFQGLMQLRDLDLSYGGLAFLSLEALEGLPGLVTLQIGGNPWVC
190 200 210 220 230 240
210 220 230 240 250 260
pF1KE5 GCALRPLCAWLR-RHPLPASEAETVLCVWPGRLTLSPLTAFSDAAFSHCAQPLALRDLAV
::...:: ::: : ..... . : : .. .:: .... .:. : :.: :
CCDS31 GCTMEPLLKWLRNRIQRCTADSQLAECRGPPEVEGAPLFSLTEESFKACHLTLTLDDYLF
250 260 270 280 290 300
270 280 290 300 310 320
pF1KE5 VYTLGPASFLVSLASCLALGSGLTACRARRRRLRTAALRPPRPPDPNPDPDPHGCASPAD
. .: . ..:.:. . :: . :
CCDS31 IAFVGFVVSIASVATNFLLGITANCCHRWSKASEEEEI
310 320 330 340
>>CCDS7453.1 SLIT1 gene_id:6585|Hs108|chr10 (1534 aa)
initn: 1205 init1: 292 opt: 419 Z-score: 337.4 bits: 73.0 E(32554): 1.8e-12
Smith-Waterman score: 419; 35.8% identity (63.7% similar) in 204 aa overlap (34-237:273-472)
10 20 30 40 50 60
pF1KE5 PSWLRPRPLLLLLLLLSPWPVWAHVSATASPSGSLGAPDCPEVCTCVPGGLASCSALSLP
:. .:.. .:: .::: .:...: . .:
CCDS74 SGPASLRGLNVAEVQKSEFSCSGQGEAGRVPTCTLSSGSCPAMCTC-SNGIVDCRGKGLT
250 260 270 280 290 300
70 80 90 100 110 120
pF1KE5 AVPPGLSLRLRALLLDHNRVRALPPGAFAGAGALQRLDLRENGLHSVHVRAFWGLGALQL
:.: .: . . :. : ....:::::. :.:.:: .: . . :: :: .:.
CCDS74 AIPANLPETMTEIRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNS
310 320 330 340 350 360
130 140 150 160 170 180
pF1KE5 LDLSANQLEALAPGTFAPLRALRNLSLAGNRLARLEPAALGALPLLRSLSLQDNELAALA
: : .:.. : :.:. : .:. : : .:.. ..: :. : : ::: ::.. .::
CCDS74 LVLYGNKITDLPRGVFGGLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSLA
370 380 390 400 410 420
190 200 210 220 230 240
pF1KE5 PGLLGRLPALDALHLRGNPWGCGCALRPLCAWLRRHPLPASEAETVLCVWPGRLTLSPLT
: . : :...::: ::. : : :. : .:: .:. .: :. :. : ::
CCDS74 KGTFTSLRAIQTLHLAQNPFICDCNLKWLADFLRTNPIETSGAR---CASPRRLANKRIG
430 440 450 460 470
250 260 270 280 290 300
pF1KE5 AFSDAAFSHCAQPLALRDLAVVYTLGPASFLVSLASCLALGSGLTACRARRRRLRTAALR
CCDS74 QIKSKKFRCSAKEQYFIPGTEDYQLNSECNSDVVCPHKCRCEANVVECSSLKLTKIPERI
480 490 500 510 520 530
>>CCDS10259.1 ISLR2 gene_id:57611|Hs108|chr15 (745 aa)
initn: 411 init1: 334 opt: 399 Z-score: 325.4 bits: 69.7 E(32554): 8.4e-12
Smith-Waterman score: 399; 35.7% identity (57.6% similar) in 238 aa overlap (22-256:8-233)
10 20 30 40 50
pF1KE5 MRGPSWLRPRPLLLLLLLLSPWPVWAHVSATASPSGSLGAPDCPEVCTCVPG---GLASC
: ::: .....: ::: :.:: .:.:
CCDS10 MFPLRALWLVWALLGVAGS---------CPEPCACVDKYAHQFADC
10 20 30
60 70 80 90 100 110
pF1KE5 SALSLPAVPPGLSLRLRALLLDHNRVRALPPGAFAGAGALQRLDLRENGLHSVHVRAFWG
. : :: :: . .: :. :.. .: :::: . . : : .: ...:. :.
CCDS10 AYKELREVPEGLPANVTTLSLSANKITVLRRGAFADVTQVTSLWLAHNEVRTVEPGALAV
40 50 60 70 80 90
120 130 140 150 160 170
pF1KE5 LGALQLLDLSANQLEALAPGTFAPLRALRNLSLAGNRLARLEPAALGALPLLRSLSLQDN
:. :. :::: : . .. . . : ::. :.. :::. : :::::: :::: ...:
CCDS10 LSQLKNLDLSHNFISSFPWSDLRNLSALQLLKMNHNRLGSLPRDALGALPDLRSLRINNN
100 110 120 130 140 150
180 190 200 210 220 230
pF1KE5 ELAALAPGLLGRLPALDALHLRGNPWGCGCALRPLCAWLRRHPLPASEAETVLCVWPGRL
.: .:::: . : ::. :.: ::. :::.: : :: . : ... :. : :
CCDS10 RLRTLAPGTFDALSALSHLQLYHNPFHCGCGLVWLQAWAASTRVSLPEPDSIACASPPAL
160 170 180 190 200 210
240 250 260 270 280 290
pF1KE5 TLSPLTAFSDAAFSHCAQPLALRDLAVVYTLGPASFLVSLASCLALGSGLTACRARRRRL
:. . :. :: :
CCDS10 QGVPV--YRLPALP-CAPPSVHLSAEPPLEAPGTPLRAGLAFVLHCIADGHPTPRLQWQL
220 230 240 250 260 270
>>CCDS31726.1 LRTM2 gene_id:654429|Hs108|chr12 (370 aa)
initn: 353 init1: 353 opt: 390 Z-score: 322.0 bits: 68.1 E(32554): 1.3e-11
Smith-Waterman score: 390; 34.7% identity (58.3% similar) in 216 aa overlap (41-255:37-252)
20 30 40 50 60
pF1KE5 PLLLLLLLLSPWPVWAHVSATASPSGSLGAPDCPEVCTCVPGGL-ASCSALSLPAVPPGL
: :: : : .: ..::.:.: .::: .
CCDS31 SPGQRGRLALQWRQVSWITCWIALYAVEALPTCPFSCKCDSRSLEVDCSGLGLTTVPPDV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 SLRLRALLLDHNRVRALPPGAFAGAGALQRLDLRENGLHSVHVRAFWGLGALQLLDLSAN
:.::: .:.. ::: :::. ..:::::: .: : . : : : :.: :
CCDS31 PAATRTLLLLNNKLSALPSWAFANLSSLQRLDLSNNFLDRLPRSIFGDLTNLTELQLRNN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 QLEALAPGTFAPLRALRNLSLAGNRLARLEPAALGALPLLRSLSLQDNELAALAPGLLGR
....: . ::.:.:. : ::.: :. . .: ::::::..:.: : .
CCDS31 SIRTLDRDLLRHSPLLRHLDLSINGLAQLPPGLFDGLLALRSLSLRSNRLQNLDRLTFEP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 LPALDALHLRGNPWGCGCALRPLCAWLRRHPLPASEAETVLCVWPGRLTLSPLTAFSDAA
: :. :.. ::: : : :: . :.. ... . . :. : .: . .
CCDS31 LANLQLLQVGDNPWECDCNLREFKHWMEWFSYRGGRLDQLACTLPKELRGKDMRMVPMEM
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 FSHCAQPLALRDLAVVYTLGPASFLVSLASCLALGSGLTACRARRRRLRTAALRPPRPPD
:..:.:
CCDS31 FNYCSQLEDENSSAGLDIPGPPCTKASPEPAKPKPGAEPEPEPSTACPQKQRHRPASVRR
250 260 270 280 290 300
334 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 04:11:13 2016 done: Tue Nov 8 04:11:14 2016
Total Scan time: 3.380 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]