Result of FASTA (omim) for
pFN21AE5006
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5006, 321 aa
1>>>pF1KE5006 321 - 321 aa - 321 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.7434+/-0.000463; mu= 13.1411+/- 0.029
mean_var=69.0752+/-13.773, 0's: 0 Z-trim(108.6): 41 B-trim: 178 in 1/51
Lambda= 0.154317
statistics sampled from 16658 (16691) to 16658 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.556), E-opt: 0.2 (0.196), width: 16
Scan time: 5.100
The best scores are: opt bits E(85289)
XP_011540043 (OMIM: 607400) PREDICTED: mucolipin-3 ( 445) 2115 480.5 2.8e-135
NP_060768 (OMIM: 607400) mucolipin-3 isoform 1 [Ho ( 553) 2115 480.5 3.5e-135
XP_005271060 (OMIM: 607400) PREDICTED: mucolipin-3 ( 553) 2115 480.5 3.5e-135
XP_006710813 (OMIM: 607400) PREDICTED: mucolipin-3 ( 553) 2115 480.5 3.5e-135
XP_011540041 (OMIM: 607400) PREDICTED: mucolipin-3 ( 566) 2115 480.5 3.5e-135
NP_001240622 (OMIM: 607400) mucolipin-3 isoform 2 ( 497) 1239 285.4 1.6e-76
XP_011540042 (OMIM: 607400) PREDICTED: mucolipin-3 ( 521) 1239 285.5 1.7e-76
XP_011540044 (OMIM: 607400) PREDICTED: mucolipin-3 ( 398) 1084 250.9 3.2e-66
XP_005270776 (OMIM: 607399) PREDICTED: mucolipin-2 ( 538) 999 232.0 2.1e-60
XP_011539490 (OMIM: 607399) PREDICTED: mucolipin-2 ( 538) 999 232.0 2.1e-60
XP_011539489 (OMIM: 607399) PREDICTED: mucolipin-2 ( 538) 999 232.0 2.1e-60
NP_001317576 (OMIM: 607399) mucolipin-2 isoform 2 ( 538) 999 232.0 2.1e-60
NP_694991 (OMIM: 607399) mucolipin-2 isoform 1 [Ho ( 566) 999 232.0 2.2e-60
XP_016856412 (OMIM: 607399) PREDICTED: mucolipin-2 ( 287) 843 197.2 3.4e-50
NP_065394 (OMIM: 252650,605248) mucolipin-1 [Homo ( 580) 637 151.4 4.1e-36
>>XP_011540043 (OMIM: 607400) PREDICTED: mucolipin-3 iso (445 aa)
initn: 2115 init1: 2115 opt: 2115 Z-score: 2549.5 bits: 480.5 E(85289): 2.8e-135
Smith-Waterman score: 2115; 99.7% identity (100.0% similar) in 315 aa overlap (1-315:25-339)
10 20 30
pF1KE5 MADPEVVVSSCSSHEEENRCNFNQQTSPSEELLLED
::::::::::::::::::::::::::::::::::::
XP_011 MEGRRAGAGREMQLFRAAPKPPAEMADPEVVVSSCSSHEEENRCNFNQQTSPSEELLLED
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE5 QMRRKLKFFFMNPCEKFWARGRKPWKLAIQILKIAMVTIQLVLFGLSNQMVVAFKEENTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QMRRKLKFFFMNPCEKFWARGRKPWKLAIQILKIAMVTIQLVLFGLSNQMVVAFKEENTI
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE5 AFKHLFLKGYMDRMDDTYAVYTQSDVYDQLIFAVNQYLQLYNVSVGNHAYENKGTKQSAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AFKHLFLKGYMDRMDDTYAVYTQSDVYDQLIFAVNQYLQLYNVSVGNHAYENKGTKQSAM
130 140 150 160 170 180
160 170 180 190 200 210
pF1KE5 AICQHLYKRGNIYPGNDTFDIDPEIETECFFVEPDEPFHIGTPAENKLNLTLDFHRLLTV
:::::.::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AICQHFYKRGNIYPGNDTFDIDPEIETECFFVEPDEPFHIGTPAENKLNLTLDFHRLLTV
190 200 210 220 230 240
220 230 240 250 260 270
pF1KE5 ELQFKLKAINLQTVRHQELPDCYDFTLTITFDNKAHSGRIKISLDNDISIRECKDWHVSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELQFKLKAINLQTVRHQELPDCYDFTLTITFDNKAHSGRIKISLDNDISIRECKDWHVSG
250 260 270 280 290 300
280 290 300 310 320
pF1KE5 SIQKNTHYMMIFDAFVILTCLVSLILCIRSVIRGLQLQQVGNVAF
:::::::::::::::::::::::::::::::::::::::
XP_011 SIQKNTHYMMIFDAFVILTCLVSLILCIRSVIRGLQLQQEFVNFFLLHYKKEVSVSDQME
310 320 330 340 350 360
XP_011 FVNGWYIMIIISDILTIIGSILKMEIQAKSGGLLGRVFQSVIHKPLHQNHWVPGKVYHVR
370 380 390 400 410 420
>>NP_060768 (OMIM: 607400) mucolipin-3 isoform 1 [Homo s (553 aa)
initn: 2115 init1: 2115 opt: 2115 Z-score: 2548.0 bits: 480.5 E(85289): 3.5e-135
Smith-Waterman score: 2115; 99.7% identity (100.0% similar) in 315 aa overlap (1-315:1-315)
10 20 30 40 50 60
pF1KE5 MADPEVVVSSCSSHEEENRCNFNQQTSPSEELLLEDQMRRKLKFFFMNPCEKFWARGRKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 MADPEVVVSSCSSHEEENRCNFNQQTSPSEELLLEDQMRRKLKFFFMNPCEKFWARGRKP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 WKLAIQILKIAMVTIQLVLFGLSNQMVVAFKEENTIAFKHLFLKGYMDRMDDTYAVYTQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 WKLAIQILKIAMVTIQLVLFGLSNQMVVAFKEENTIAFKHLFLKGYMDRMDDTYAVYTQS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 DVYDQLIFAVNQYLQLYNVSVGNHAYENKGTKQSAMAICQHLYKRGNIYPGNDTFDIDPE
:::::::::::::::::::::::::::::::::::::::::.::::::::::::::::::
NP_060 DVYDQLIFAVNQYLQLYNVSVGNHAYENKGTKQSAMAICQHFYKRGNIYPGNDTFDIDPE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 IETECFFVEPDEPFHIGTPAENKLNLTLDFHRLLTVELQFKLKAINLQTVRHQELPDCYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 IETECFFVEPDEPFHIGTPAENKLNLTLDFHRLLTVELQFKLKAINLQTVRHQELPDCYD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 FTLTITFDNKAHSGRIKISLDNDISIRECKDWHVSGSIQKNTHYMMIFDAFVILTCLVSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 FTLTITFDNKAHSGRIKISLDNDISIRECKDWHVSGSIQKNTHYMMIFDAFVILTCLVSL
250 260 270 280 290 300
310 320
pF1KE5 ILCIRSVIRGLQLQQVGNVAF
:::::::::::::::
NP_060 ILCIRSVIRGLQLQQEFVNFFLLHYKKEVSVSDQMEFVNGWYIMIIISDILTIIGSILKM
310 320 330 340 350 360
>>XP_005271060 (OMIM: 607400) PREDICTED: mucolipin-3 iso (553 aa)
initn: 2115 init1: 2115 opt: 2115 Z-score: 2548.0 bits: 480.5 E(85289): 3.5e-135
Smith-Waterman score: 2115; 99.7% identity (100.0% similar) in 315 aa overlap (1-315:1-315)
10 20 30 40 50 60
pF1KE5 MADPEVVVSSCSSHEEENRCNFNQQTSPSEELLLEDQMRRKLKFFFMNPCEKFWARGRKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MADPEVVVSSCSSHEEENRCNFNQQTSPSEELLLEDQMRRKLKFFFMNPCEKFWARGRKP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 WKLAIQILKIAMVTIQLVLFGLSNQMVVAFKEENTIAFKHLFLKGYMDRMDDTYAVYTQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 WKLAIQILKIAMVTIQLVLFGLSNQMVVAFKEENTIAFKHLFLKGYMDRMDDTYAVYTQS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 DVYDQLIFAVNQYLQLYNVSVGNHAYENKGTKQSAMAICQHLYKRGNIYPGNDTFDIDPE
:::::::::::::::::::::::::::::::::::::::::.::::::::::::::::::
XP_005 DVYDQLIFAVNQYLQLYNVSVGNHAYENKGTKQSAMAICQHFYKRGNIYPGNDTFDIDPE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 IETECFFVEPDEPFHIGTPAENKLNLTLDFHRLLTVELQFKLKAINLQTVRHQELPDCYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IETECFFVEPDEPFHIGTPAENKLNLTLDFHRLLTVELQFKLKAINLQTVRHQELPDCYD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 FTLTITFDNKAHSGRIKISLDNDISIRECKDWHVSGSIQKNTHYMMIFDAFVILTCLVSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FTLTITFDNKAHSGRIKISLDNDISIRECKDWHVSGSIQKNTHYMMIFDAFVILTCLVSL
250 260 270 280 290 300
310 320
pF1KE5 ILCIRSVIRGLQLQQVGNVAF
:::::::::::::::
XP_005 ILCIRSVIRGLQLQQEFVNFFLLHYKKEVSVSDQMEFVNGWYIMIIISDILTIIGSILKM
310 320 330 340 350 360
>>XP_006710813 (OMIM: 607400) PREDICTED: mucolipin-3 iso (553 aa)
initn: 2115 init1: 2115 opt: 2115 Z-score: 2548.0 bits: 480.5 E(85289): 3.5e-135
Smith-Waterman score: 2115; 99.7% identity (100.0% similar) in 315 aa overlap (1-315:1-315)
10 20 30 40 50 60
pF1KE5 MADPEVVVSSCSSHEEENRCNFNQQTSPSEELLLEDQMRRKLKFFFMNPCEKFWARGRKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MADPEVVVSSCSSHEEENRCNFNQQTSPSEELLLEDQMRRKLKFFFMNPCEKFWARGRKP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 WKLAIQILKIAMVTIQLVLFGLSNQMVVAFKEENTIAFKHLFLKGYMDRMDDTYAVYTQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 WKLAIQILKIAMVTIQLVLFGLSNQMVVAFKEENTIAFKHLFLKGYMDRMDDTYAVYTQS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 DVYDQLIFAVNQYLQLYNVSVGNHAYENKGTKQSAMAICQHLYKRGNIYPGNDTFDIDPE
:::::::::::::::::::::::::::::::::::::::::.::::::::::::::::::
XP_006 DVYDQLIFAVNQYLQLYNVSVGNHAYENKGTKQSAMAICQHFYKRGNIYPGNDTFDIDPE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 IETECFFVEPDEPFHIGTPAENKLNLTLDFHRLLTVELQFKLKAINLQTVRHQELPDCYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IETECFFVEPDEPFHIGTPAENKLNLTLDFHRLLTVELQFKLKAINLQTVRHQELPDCYD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 FTLTITFDNKAHSGRIKISLDNDISIRECKDWHVSGSIQKNTHYMMIFDAFVILTCLVSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FTLTITFDNKAHSGRIKISLDNDISIRECKDWHVSGSIQKNTHYMMIFDAFVILTCLVSL
250 260 270 280 290 300
310 320
pF1KE5 ILCIRSVIRGLQLQQVGNVAF
:::::::::::::::
XP_006 ILCIRSVIRGLQLQQEFVNFFLLHYKKEVSVSDQMEFVNGWYIMIIISDILTIIGSILKM
310 320 330 340 350 360
>>XP_011540041 (OMIM: 607400) PREDICTED: mucolipin-3 iso (566 aa)
initn: 2115 init1: 2115 opt: 2115 Z-score: 2547.9 bits: 480.5 E(85289): 3.5e-135
Smith-Waterman score: 2115; 99.7% identity (100.0% similar) in 315 aa overlap (1-315:14-328)
10 20 30 40
pF1KE5 MADPEVVVSSCSSHEEENRCNFNQQTSPSEELLLEDQMRRKLKFFFM
:::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MQLFRAAPKPPAEMADPEVVVSSCSSHEEENRCNFNQQTSPSEELLLEDQMRRKLKFFFM
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE5 NPCEKFWARGRKPWKLAIQILKIAMVTIQLVLFGLSNQMVVAFKEENTIAFKHLFLKGYM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NPCEKFWARGRKPWKLAIQILKIAMVTIQLVLFGLSNQMVVAFKEENTIAFKHLFLKGYM
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE5 DRMDDTYAVYTQSDVYDQLIFAVNQYLQLYNVSVGNHAYENKGTKQSAMAICQHLYKRGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::.:::::
XP_011 DRMDDTYAVYTQSDVYDQLIFAVNQYLQLYNVSVGNHAYENKGTKQSAMAICQHFYKRGN
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE5 IYPGNDTFDIDPEIETECFFVEPDEPFHIGTPAENKLNLTLDFHRLLTVELQFKLKAINL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IYPGNDTFDIDPEIETECFFVEPDEPFHIGTPAENKLNLTLDFHRLLTVELQFKLKAINL
190 200 210 220 230 240
230 240 250 260 270 280
pF1KE5 QTVRHQELPDCYDFTLTITFDNKAHSGRIKISLDNDISIRECKDWHVSGSIQKNTHYMMI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QTVRHQELPDCYDFTLTITFDNKAHSGRIKISLDNDISIRECKDWHVSGSIQKNTHYMMI
250 260 270 280 290 300
290 300 310 320
pF1KE5 FDAFVILTCLVSLILCIRSVIRGLQLQQVGNVAF
::::::::::::::::::::::::::::
XP_011 FDAFVILTCLVSLILCIRSVIRGLQLQQEFVNFFLLHYKKEVSVSDQMEFVNGWYIMIII
310 320 330 340 350 360
>>NP_001240622 (OMIM: 607400) mucolipin-3 isoform 2 [Hom (497 aa)
initn: 1239 init1: 1239 opt: 1239 Z-score: 1494.8 bits: 285.4 E(85289): 1.6e-76
Smith-Waterman score: 1633; 81.9% identity (82.2% similar) in 315 aa overlap (1-315:1-259)
10 20 30 40 50 60
pF1KE5 MADPEVVVSSCSSHEEENRCNFNQQTSPSEELLLEDQMRRKLKFFFMNPCEKFWARGRKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MADPEVVVSSCSSHEEENRCNFNQQTSPSEELLLEDQMRRKLKFFFMNPCEKFWARGRKP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 WKLAIQILKIAMVTIQLVLFGLSNQMVVAFKEENTIAFKHLFLKGYMDRMDDTYAVYTQS
::::::::::::::::
NP_001 WKLAIQILKIAMVTIQ--------------------------------------------
70
130 140 150 160 170 180
pF1KE5 DVYDQLIFAVNQYLQLYNVSVGNHAYENKGTKQSAMAICQHLYKRGNIYPGNDTFDIDPE
:::::::::::::::::::::::::::::.::::::::::::::::::
NP_001 ------------YLQLYNVSVGNHAYENKGTKQSAMAICQHFYKRGNIYPGNDTFDIDPE
80 90 100 110 120
190 200 210 220 230 240
pF1KE5 IETECFFVEPDEPFHIGTPAENKLNLTLDFHRLLTVELQFKLKAINLQTVRHQELPDCYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IETECFFVEPDEPFHIGTPAENKLNLTLDFHRLLTVELQFKLKAINLQTVRHQELPDCYD
130 140 150 160 170 180
250 260 270 280 290 300
pF1KE5 FTLTITFDNKAHSGRIKISLDNDISIRECKDWHVSGSIQKNTHYMMIFDAFVILTCLVSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FTLTITFDNKAHSGRIKISLDNDISIRECKDWHVSGSIQKNTHYMMIFDAFVILTCLVSL
190 200 210 220 230 240
310 320
pF1KE5 ILCIRSVIRGLQLQQVGNVAF
:::::::::::::::
NP_001 ILCIRSVIRGLQLQQEFVNFFLLHYKKEVSVSDQMEFVNGWYIMIIISDILTIIGSILKM
250 260 270 280 290 300
>>XP_011540042 (OMIM: 607400) PREDICTED: mucolipin-3 iso (521 aa)
initn: 1239 init1: 1239 opt: 1239 Z-score: 1494.4 bits: 285.5 E(85289): 1.7e-76
Smith-Waterman score: 1633; 81.9% identity (82.2% similar) in 315 aa overlap (1-315:25-283)
10 20 30
pF1KE5 MADPEVVVSSCSSHEEENRCNFNQQTSPSEELLLED
::::::::::::::::::::::::::::::::::::
XP_011 MEGRRAGAGREMQLFRAAPKPPAEMADPEVVVSSCSSHEEENRCNFNQQTSPSEELLLED
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE5 QMRRKLKFFFMNPCEKFWARGRKPWKLAIQILKIAMVTIQLVLFGLSNQMVVAFKEENTI
::::::::::::::::::::::::::::::::::::::::
XP_011 QMRRKLKFFFMNPCEKFWARGRKPWKLAIQILKIAMVTIQ--------------------
70 80 90 100
100 110 120 130 140 150
pF1KE5 AFKHLFLKGYMDRMDDTYAVYTQSDVYDQLIFAVNQYLQLYNVSVGNHAYENKGTKQSAM
::::::::::::::::::::::::
XP_011 ------------------------------------YLQLYNVSVGNHAYENKGTKQSAM
110 120
160 170 180 190 200 210
pF1KE5 AICQHLYKRGNIYPGNDTFDIDPEIETECFFVEPDEPFHIGTPAENKLNLTLDFHRLLTV
:::::.::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AICQHFYKRGNIYPGNDTFDIDPEIETECFFVEPDEPFHIGTPAENKLNLTLDFHRLLTV
130 140 150 160 170 180
220 230 240 250 260 270
pF1KE5 ELQFKLKAINLQTVRHQELPDCYDFTLTITFDNKAHSGRIKISLDNDISIRECKDWHVSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELQFKLKAINLQTVRHQELPDCYDFTLTITFDNKAHSGRIKISLDNDISIRECKDWHVSG
190 200 210 220 230 240
280 290 300 310 320
pF1KE5 SIQKNTHYMMIFDAFVILTCLVSLILCIRSVIRGLQLQQVGNVAF
:::::::::::::::::::::::::::::::::::::::
XP_011 SIQKNTHYMMIFDAFVILTCLVSLILCIRSVIRGLQLQQEFVNFFLLHYKKEVSVSDQME
250 260 270 280 290 300
XP_011 FVNGWYIMIIISDILTIIGSILKMEIQAKSLTSYDVCSILLGTSTMLVWLGVIRYLGFFA
310 320 330 340 350 360
>>XP_011540044 (OMIM: 607400) PREDICTED: mucolipin-3 iso (398 aa)
initn: 1084 init1: 1084 opt: 1084 Z-score: 1309.8 bits: 250.9 E(85289): 3.2e-66
Smith-Waterman score: 1084; 99.4% identity (100.0% similar) in 160 aa overlap (156-315:1-160)
130 140 150 160 170 180
pF1KE5 LIFAVNQYLQLYNVSVGNHAYENKGTKQSAMAICQHLYKRGNIYPGNDTFDIDPEIETEC
::::::.:::::::::::::::::::::::
XP_011 MAICQHFYKRGNIYPGNDTFDIDPEIETEC
10 20 30
190 200 210 220 230 240
pF1KE5 FFVEPDEPFHIGTPAENKLNLTLDFHRLLTVELQFKLKAINLQTVRHQELPDCYDFTLTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FFVEPDEPFHIGTPAENKLNLTLDFHRLLTVELQFKLKAINLQTVRHQELPDCYDFTLTI
40 50 60 70 80 90
250 260 270 280 290 300
pF1KE5 TFDNKAHSGRIKISLDNDISIRECKDWHVSGSIQKNTHYMMIFDAFVILTCLVSLILCIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TFDNKAHSGRIKISLDNDISIRECKDWHVSGSIQKNTHYMMIFDAFVILTCLVSLILCIR
100 110 120 130 140 150
310 320
pF1KE5 SVIRGLQLQQVGNVAF
::::::::::
XP_011 SVIRGLQLQQEFVNFFLLHYKKEVSVSDQMEFVNGWYIMIIISDILTIIGSILKMEIQAK
160 170 180 190 200 210
>>XP_005270776 (OMIM: 607399) PREDICTED: mucolipin-2 iso (538 aa)
initn: 1032 init1: 646 opt: 999 Z-score: 1205.5 bits: 232.0 E(85289): 2.1e-60
Smith-Waterman score: 999; 51.2% identity (81.3% similar) in 283 aa overlap (35-315:10-292)
10 20 30 40 50 60
pF1KE5 EVVVSSCSSHEEENRCNFNQQTSPSEELLLEDQMRRKLKFFFMNPCEKFWARGRKPWKLA
:. .:. :::.::.::::. :: . ::::.
XP_005 MAHRDSEMKEECLREDLKFYFMSPCEKYRARRQIPWKLG
10 20 30
70 80 90 100 110 120
pF1KE5 IQILKIAMVTIQLVLFGLSNQMVVAFKEENTIAFKHLFLKGYMDRMDDTYA--VYTQSDV
.:::::.::: ::: ::::::.::::::.::.:::::::::: .: :. :::: :.
XP_005 LQILKIVMVTTQLVRFGLSNQLVVAFKEDNTVAFKHLFLKGYSGTDEDDYSCSVYTQEDA
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE5 YDQLIFAVNQYLQLYNVSVGNHAYENKGTKQSAMAICQHLYKRGNIYPGNDTFDIDPEIE
:....::.::: :: ....:. .: .. .. .. .:.. ::.:...:.:.:..:: ..:
XP_005 YESIFFAINQYHQLKDITLGTLGYGENEDNRIGLKVCKQHYKKGTMFPSNETLNIDNDVE
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE5 TECFFVEPDEPFHIGTPAENKLNLTLDFHRLLTVELQFKLKAINLQTVRHQELPDCYDFT
.: .. .. . .:. . :.:.::: ::..:.::.:.:::.. .:::::: :
XP_005 LDCVQLDLQDLSKKPPDWKNSSFFRLEFYRLLQVEISFHLKGIDLQTIHSRELPDCYVFQ
160 170 180 190 200 210
250 260 270 280 290 300
pF1KE5 LTITFDNKAHSGRIKISLDNDISIRECKDWHVSGSIQKNTHYMMIFDAFVILTCLVSLIL
:: ::::::::.::: .:.: .:.:::: .. :: :::..:...::::::. ::.::::
XP_005 NTIIFDNKAHSGKIKIYFDSDAKIEECKDLNIFGSTQKNAQYVLVFDAFVIVICLASLIL
220 230 240 250 260 270
310 320
pF1KE5 CIRSVIRGLQLQQVGNVAF
: ::.. .:.:..
XP_005 CTRSIVLALRLRKRFLNFFLEKYKRPVCDTDQWEFINGWYVLVIISDLMTIIGSILKMEI
280 290 300 310 320 330
>>XP_011539490 (OMIM: 607399) PREDICTED: mucolipin-2 iso (538 aa)
initn: 1032 init1: 646 opt: 999 Z-score: 1205.5 bits: 232.0 E(85289): 2.1e-60
Smith-Waterman score: 999; 51.2% identity (81.3% similar) in 283 aa overlap (35-315:10-292)
10 20 30 40 50 60
pF1KE5 EVVVSSCSSHEEENRCNFNQQTSPSEELLLEDQMRRKLKFFFMNPCEKFWARGRKPWKLA
:. .:. :::.::.::::. :: . ::::.
XP_011 MAHRDSEMKEECLREDLKFYFMSPCEKYRARRQIPWKLG
10 20 30
70 80 90 100 110 120
pF1KE5 IQILKIAMVTIQLVLFGLSNQMVVAFKEENTIAFKHLFLKGYMDRMDDTYA--VYTQSDV
.:::::.::: ::: ::::::.::::::.::.:::::::::: .: :. :::: :.
XP_011 LQILKIVMVTTQLVRFGLSNQLVVAFKEDNTVAFKHLFLKGYSGTDEDDYSCSVYTQEDA
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE5 YDQLIFAVNQYLQLYNVSVGNHAYENKGTKQSAMAICQHLYKRGNIYPGNDTFDIDPEIE
:....::.::: :: ....:. .: .. .. .. .:.. ::.:...:.:.:..:: ..:
XP_011 YESIFFAINQYHQLKDITLGTLGYGENEDNRIGLKVCKQHYKKGTMFPSNETLNIDNDVE
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE5 TECFFVEPDEPFHIGTPAENKLNLTLDFHRLLTVELQFKLKAINLQTVRHQELPDCYDFT
.: .. .. . .:. . :.:.::: ::..:.::.:.:::.. .:::::: :
XP_011 LDCVQLDLQDLSKKPPDWKNSSFFRLEFYRLLQVEISFHLKGIDLQTIHSRELPDCYVFQ
160 170 180 190 200 210
250 260 270 280 290 300
pF1KE5 LTITFDNKAHSGRIKISLDNDISIRECKDWHVSGSIQKNTHYMMIFDAFVILTCLVSLIL
:: ::::::::.::: .:.: .:.:::: .. :: :::..:...::::::. ::.::::
XP_011 NTIIFDNKAHSGKIKIYFDSDAKIEECKDLNIFGSTQKNAQYVLVFDAFVIVICLASLIL
220 230 240 250 260 270
310 320
pF1KE5 CIRSVIRGLQLQQVGNVAF
: ::.. .:.:..
XP_011 CTRSIVLALRLRKRFLNFFLEKYKRPVCDTDQWEFINGWYVLVIISDLMTIIGSILKMEI
280 290 300 310 320 330
321 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 04:05:31 2016 done: Tue Nov 8 04:05:32 2016
Total Scan time: 5.100 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]