Result of FASTA (ccds) for
pFN21AE5006
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5006, 321 aa
1>>>pF1KE5006 321 - 321 aa - 321 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.7071+/-0.00108; mu= 13.0977+/- 0.065
mean_var=61.3127+/-11.995, 0's: 0 Z-trim(101.8): 24 B-trim: 0 in 0/49
Lambda= 0.163794
statistics sampled from 6642 (6652) to 6642 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.576), E-opt: 0.2 (0.204), width: 16
Scan time: 1.600
The best scores are: opt bits E(32554)
CCDS701.1 MCOLN3 gene_id:55283|Hs108|chr1 ( 553) 2115 508.7 4.1e-144
CCDS58009.1 MCOLN3 gene_id:55283|Hs108|chr1 ( 497) 1239 301.7 7.7e-82
CCDS81347.1 MCOLN2 gene_id:255231|Hs108|chr1 ( 538) 999 245.0 9.8e-65
CCDS30762.1 MCOLN2 gene_id:255231|Hs108|chr1 ( 566) 999 245.0 1e-64
CCDS12180.1 MCOLN1 gene_id:57192|Hs108|chr19 ( 580) 637 159.5 5.9e-39
>>CCDS701.1 MCOLN3 gene_id:55283|Hs108|chr1 (553 aa)
initn: 2115 init1: 2115 opt: 2115 Z-score: 2700.7 bits: 508.7 E(32554): 4.1e-144
Smith-Waterman score: 2115; 99.7% identity (100.0% similar) in 315 aa overlap (1-315:1-315)
10 20 30 40 50 60
pF1KE5 MADPEVVVSSCSSHEEENRCNFNQQTSPSEELLLEDQMRRKLKFFFMNPCEKFWARGRKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS70 MADPEVVVSSCSSHEEENRCNFNQQTSPSEELLLEDQMRRKLKFFFMNPCEKFWARGRKP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 WKLAIQILKIAMVTIQLVLFGLSNQMVVAFKEENTIAFKHLFLKGYMDRMDDTYAVYTQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS70 WKLAIQILKIAMVTIQLVLFGLSNQMVVAFKEENTIAFKHLFLKGYMDRMDDTYAVYTQS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 DVYDQLIFAVNQYLQLYNVSVGNHAYENKGTKQSAMAICQHLYKRGNIYPGNDTFDIDPE
:::::::::::::::::::::::::::::::::::::::::.::::::::::::::::::
CCDS70 DVYDQLIFAVNQYLQLYNVSVGNHAYENKGTKQSAMAICQHFYKRGNIYPGNDTFDIDPE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 IETECFFVEPDEPFHIGTPAENKLNLTLDFHRLLTVELQFKLKAINLQTVRHQELPDCYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS70 IETECFFVEPDEPFHIGTPAENKLNLTLDFHRLLTVELQFKLKAINLQTVRHQELPDCYD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 FTLTITFDNKAHSGRIKISLDNDISIRECKDWHVSGSIQKNTHYMMIFDAFVILTCLVSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS70 FTLTITFDNKAHSGRIKISLDNDISIRECKDWHVSGSIQKNTHYMMIFDAFVILTCLVSL
250 260 270 280 290 300
310 320
pF1KE5 ILCIRSVIRGLQLQQVGNVAF
:::::::::::::::
CCDS70 ILCIRSVIRGLQLQQEFVNFFLLHYKKEVSVSDQMEFVNGWYIMIIISDILTIIGSILKM
310 320 330 340 350 360
>>CCDS58009.1 MCOLN3 gene_id:55283|Hs108|chr1 (497 aa)
initn: 1239 init1: 1239 opt: 1239 Z-score: 1582.7 bits: 301.7 E(32554): 7.7e-82
Smith-Waterman score: 1633; 81.9% identity (82.2% similar) in 315 aa overlap (1-315:1-259)
10 20 30 40 50 60
pF1KE5 MADPEVVVSSCSSHEEENRCNFNQQTSPSEELLLEDQMRRKLKFFFMNPCEKFWARGRKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 MADPEVVVSSCSSHEEENRCNFNQQTSPSEELLLEDQMRRKLKFFFMNPCEKFWARGRKP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 WKLAIQILKIAMVTIQLVLFGLSNQMVVAFKEENTIAFKHLFLKGYMDRMDDTYAVYTQS
::::::::::::::::
CCDS58 WKLAIQILKIAMVTIQ--------------------------------------------
70
130 140 150 160 170 180
pF1KE5 DVYDQLIFAVNQYLQLYNVSVGNHAYENKGTKQSAMAICQHLYKRGNIYPGNDTFDIDPE
:::::::::::::::::::::::::::::.::::::::::::::::::
CCDS58 ------------YLQLYNVSVGNHAYENKGTKQSAMAICQHFYKRGNIYPGNDTFDIDPE
80 90 100 110 120
190 200 210 220 230 240
pF1KE5 IETECFFVEPDEPFHIGTPAENKLNLTLDFHRLLTVELQFKLKAINLQTVRHQELPDCYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 IETECFFVEPDEPFHIGTPAENKLNLTLDFHRLLTVELQFKLKAINLQTVRHQELPDCYD
130 140 150 160 170 180
250 260 270 280 290 300
pF1KE5 FTLTITFDNKAHSGRIKISLDNDISIRECKDWHVSGSIQKNTHYMMIFDAFVILTCLVSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 FTLTITFDNKAHSGRIKISLDNDISIRECKDWHVSGSIQKNTHYMMIFDAFVILTCLVSL
190 200 210 220 230 240
310 320
pF1KE5 ILCIRSVIRGLQLQQVGNVAF
:::::::::::::::
CCDS58 ILCIRSVIRGLQLQQEFVNFFLLHYKKEVSVSDQMEFVNGWYIMIIISDILTIIGSILKM
250 260 270 280 290 300
>>CCDS81347.1 MCOLN2 gene_id:255231|Hs108|chr1 (538 aa)
initn: 1032 init1: 646 opt: 999 Z-score: 1275.6 bits: 245.0 E(32554): 9.8e-65
Smith-Waterman score: 999; 51.2% identity (81.3% similar) in 283 aa overlap (35-315:10-292)
10 20 30 40 50 60
pF1KE5 EVVVSSCSSHEEENRCNFNQQTSPSEELLLEDQMRRKLKFFFMNPCEKFWARGRKPWKLA
:. .:. :::.::.::::. :: . ::::.
CCDS81 MAHRDSEMKEECLREDLKFYFMSPCEKYRARRQIPWKLG
10 20 30
70 80 90 100 110 120
pF1KE5 IQILKIAMVTIQLVLFGLSNQMVVAFKEENTIAFKHLFLKGYMDRMDDTYA--VYTQSDV
.:::::.::: ::: ::::::.::::::.::.:::::::::: .: :. :::: :.
CCDS81 LQILKIVMVTTQLVRFGLSNQLVVAFKEDNTVAFKHLFLKGYSGTDEDDYSCSVYTQEDA
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE5 YDQLIFAVNQYLQLYNVSVGNHAYENKGTKQSAMAICQHLYKRGNIYPGNDTFDIDPEIE
:....::.::: :: ....:. .: .. .. .. .:.. ::.:...:.:.:..:: ..:
CCDS81 YESIFFAINQYHQLKDITLGTLGYGENEDNRIGLKVCKQHYKKGTMFPSNETLNIDNDVE
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE5 TECFFVEPDEPFHIGTPAENKLNLTLDFHRLLTVELQFKLKAINLQTVRHQELPDCYDFT
.: .. .. . .:. . :.:.::: ::..:.::.:.:::.. .:::::: :
CCDS81 LDCVQLDLQDLSKKPPDWKNSSFFRLEFYRLLQVEISFHLKGIDLQTIHSRELPDCYVFQ
160 170 180 190 200 210
250 260 270 280 290 300
pF1KE5 LTITFDNKAHSGRIKISLDNDISIRECKDWHVSGSIQKNTHYMMIFDAFVILTCLVSLIL
:: ::::::::.::: .:.: .:.:::: .. :: :::..:...::::::. ::.::::
CCDS81 NTIIFDNKAHSGKIKIYFDSDAKIEECKDLNIFGSTQKNAQYVLVFDAFVIVICLASLIL
220 230 240 250 260 270
310 320
pF1KE5 CIRSVIRGLQLQQVGNVAF
: ::.. .:.:..
CCDS81 CTRSIVLALRLRKRFLNFFLEKYKRPVCDTDQWEFINGWYVLVIISDLMTIIGSILKMEI
280 290 300 310 320 330
>>CCDS30762.1 MCOLN2 gene_id:255231|Hs108|chr1 (566 aa)
initn: 1032 init1: 646 opt: 999 Z-score: 1275.3 bits: 245.0 E(32554): 1e-64
Smith-Waterman score: 999; 51.2% identity (81.3% similar) in 283 aa overlap (35-315:38-320)
10 20 30 40 50 60
pF1KE5 EVVVSSCSSHEEENRCNFNQQTSPSEELLLEDQMRRKLKFFFMNPCEKFWARGRKPWKLA
:. .:. :::.::.::::. :: . ::::.
CCDS30 FPQARIPERGSGVFRLTVRNAMAHRDSEMKEECLREDLKFYFMSPCEKYRARRQIPWKLG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 IQILKIAMVTIQLVLFGLSNQMVVAFKEENTIAFKHLFLKGYMDRMDDTYA--VYTQSDV
.:::::.::: ::: ::::::.::::::.::.:::::::::: .: :. :::: :.
CCDS30 LQILKIVMVTTQLVRFGLSNQLVVAFKEDNTVAFKHLFLKGYSGTDEDDYSCSVYTQEDA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 YDQLIFAVNQYLQLYNVSVGNHAYENKGTKQSAMAICQHLYKRGNIYPGNDTFDIDPEIE
:....::.::: :: ....:. .: .. .. .. .:.. ::.:...:.:.:..:: ..:
CCDS30 YESIFFAINQYHQLKDITLGTLGYGENEDNRIGLKVCKQHYKKGTMFPSNETLNIDNDVE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 TECFFVEPDEPFHIGTPAENKLNLTLDFHRLLTVELQFKLKAINLQTVRHQELPDCYDFT
.: .. .. . .:. . :.:.::: ::..:.::.:.:::.. .:::::: :
CCDS30 LDCVQLDLQDLSKKPPDWKNSSFFRLEFYRLLQVEISFHLKGIDLQTIHSRELPDCYVFQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 LTITFDNKAHSGRIKISLDNDISIRECKDWHVSGSIQKNTHYMMIFDAFVILTCLVSLIL
:: ::::::::.::: .:.: .:.:::: .. :: :::..:...::::::. ::.::::
CCDS30 NTIIFDNKAHSGKIKIYFDSDAKIEECKDLNIFGSTQKNAQYVLVFDAFVIVICLASLIL
250 260 270 280 290 300
310 320
pF1KE5 CIRSVIRGLQLQQVGNVAF
: ::.. .:.:..
CCDS30 CTRSIVLALRLRKRFLNFFLEKYKRPVCDTDQWEFINGWYVLVIISDLMTIIGSILKMEI
310 320 330 340 350 360
>>CCDS12180.1 MCOLN1 gene_id:57192|Hs108|chr19 (580 aa)
initn: 1002 init1: 475 opt: 637 Z-score: 812.8 bits: 159.5 E(32554): 5.9e-39
Smith-Waterman score: 980; 51.0% identity (76.2% similar) in 302 aa overlap (27-314:34-327)
10 20 30 40 50
pF1KE5 MADPEVVVSSCSSHEEENRCNFNQQTSPSEELLLEDQMRRKLKFFFMNPCEKFWAR
.: :: :: .::.::.:::.::.:: :.
CCDS12 PAGPRGSETERLLTPNPGYGTQAGPSPAPPTPPEE---ED-LRRRLKYFFMSPCDKFRAK
10 20 30 40 50
60 70 80 90 100 110
pF1KE5 GRKPWKLAIQILKIAMVTIQLVLFGLSNQMVVAFKEENTIAFKHLFLKGYMDRMDDTYAV
:::: :: .:..:: .::.::.:::::::..:.:.:::::::.:::: :: : :::.:.
CCDS12 GRKPCKLMLQVVKILVVTVQLILFGLSNQLAVTFREENTIAFRHLFLLGYSDGADDTFAA
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE5 YTQSDVYDQLIFAVNQYLQLYNVSVGNHAYENKG----TKQSAMAICQHLYKRGNIYPGN
::. ..:. .. ::.::: : .::.: .:: : :. :..:.::. :.::.. :.:
CCDS12 YTREQLYQAIFHAVDQYLALPDVSLGRYAYVRGGGDPWTNGSGLALCQRYYHRGHVDPAN
120 130 140 150 160 170
180 190 200 210 220
pF1KE5 DTFDIDPEIETECFFVEPDEPFHIGTPAENKL----------NLTLDFHRLLTVELQFKL
::::::: . :.:. :.: : . : . : :::: ::.:..: ..:.:
CCDS12 DTFDIDPMVVTDCIQVDP--PERPPPPPSDDLTLLESSSSYKNLTLKFHKLVNVTIHFRL
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE5 KAINLQTVRHQELPDCYDFTLTITFDNKAHSGRIKISLDNDISIRECKDWHVSGSIQKNT
:.::::.. ..:.:::: :.. :::::::::::: :::... :.::: : : . ..
CCDS12 KTINLQSLINNEIPDCYTFSVLITFDNKAHSGRIPISLETQAHIQECK--HPSVFQHGDN
240 250 260 270 280 290
290 300 310 320
pF1KE5 HYMMIFDAFVILTCLVSLILCIRSVIRGLQLQQVGNVAF
. ..::. ::::: .:..:: ::..::. ::
CCDS12 SFRLLFDVVVILTCSLSFLLCARSLLRGFLLQNEFVGFMWRQRGRVISLWERLEFVNGWY
300 310 320 330 340 350
CCDS12 ILLVTSDVLTISGTIMKIGIEAKNLASYDVCSILLGTSTLLVWVGVIRYLTFFHNYNILI
360 370 380 390 400 410
321 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 04:05:30 2016 done: Tue Nov 8 04:05:31 2016
Total Scan time: 1.600 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]