Result of FASTA (omim) for
pFN21AE5003
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5003, 467 aa
1>>>pF1KE5003 467 - 467 aa - 467 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.7899+/-0.000345; mu= 15.8006+/- 0.022
mean_var=76.8580+/-14.928, 0's: 0 Z-trim(114.9): 37 B-trim: 213 in 1/55
Lambda= 0.146295
statistics sampled from 25035 (25072) to 25035 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.658), E-opt: 0.2 (0.294), width: 16
Scan time: 6.510
The best scores are: opt bits E(85289)
NP_006237 (OMIM: 601647) serine/threonine-protein ( 467) 3077 658.9 8.2e-189
NP_001269108 (OMIM: 601647) serine/threonine-prote ( 467) 3077 658.9 8.2e-189
NP_001269109 (OMIM: 601647) serine/threonine-prote ( 462) 3017 646.3 5.3e-185
NP_001269110 (OMIM: 601647) serine/threonine-prote ( 391) 2571 552.1 1e-156
NP_001269111 (OMIM: 601647) serine/threonine-prote ( 391) 2571 552.1 1e-156
NP_006234 (OMIM: 601643) serine/threonine-protein ( 486) 2477 532.3 1.1e-150
NP_006235 (OMIM: 601644) serine/threonine-protein ( 497) 2352 505.9 1e-142
NP_001186685 (OMIM: 601643) serine/threonine-prote ( 429) 2274 489.4 8e-138
XP_011543434 (OMIM: 601644) PREDICTED: serine/thre ( 468) 2267 488.0 2.4e-137
NP_006236 (OMIM: 601646,616355) serine/threonine-p ( 602) 2083 449.2 1.5e-125
NP_001155198 (OMIM: 601645) serine/threonine-prote ( 540) 2075 447.5 4.3e-125
XP_005267880 (OMIM: 601645) PREDICTED: serine/thre ( 545) 2075 447.5 4.3e-125
XP_005267879 (OMIM: 601645) PREDICTED: serine/thre ( 556) 2075 447.5 4.4e-125
XP_005267877 (OMIM: 601645) PREDICTED: serine/thre ( 579) 2075 447.5 4.5e-125
XP_005267876 (OMIM: 601645) PREDICTED: serine/thre ( 584) 2075 447.5 4.6e-125
XP_011543436 (OMIM: 601644) PREDICTED: serine/thre ( 411) 2065 445.3 1.5e-124
XP_011543435 (OMIM: 601644) PREDICTED: serine/thre ( 411) 2065 445.3 1.5e-124
NP_848702 (OMIM: 601645) serine/threonine-protein ( 449) 2030 437.9 2.6e-122
NP_848701 (OMIM: 601645) serine/threonine-protein ( 485) 2030 437.9 2.8e-122
NP_002710 (OMIM: 601645) serine/threonine-protein ( 524) 2030 438.0 3e-122
XP_011535220 (OMIM: 601645) PREDICTED: serine/thre ( 508) 2025 436.9 6.1e-122
XP_011535221 (OMIM: 601645) PREDICTED: serine/thre ( 508) 2025 436.9 6.1e-122
XP_011535216 (OMIM: 601645) PREDICTED: serine/thre ( 542) 2024 436.7 7.5e-122
NP_001155197 (OMIM: 601645) serine/threonine-prote ( 555) 2024 436.7 7.6e-122
XP_005267883 (OMIM: 601645) PREDICTED: serine/thre ( 500) 2022 436.3 9.3e-122
XP_011535217 (OMIM: 601645) PREDICTED: serine/thre ( 515) 2022 436.3 9.6e-122
XP_011535218 (OMIM: 601645) PREDICTED: serine/thre ( 515) 2022 436.3 9.6e-122
XP_011535223 (OMIM: 601645) PREDICTED: serine/thre ( 518) 2013 434.4 3.6e-121
XP_005267881 (OMIM: 601645) PREDICTED: serine/thre ( 539) 2009 433.5 6.7e-121
NP_851307 (OMIM: 601646,616355) serine/threonine-p ( 570) 1999 431.4 3e-120
NP_851308 (OMIM: 601646,616355) serine/threonine-p ( 496) 1991 429.7 8.7e-120
XP_016876912 (OMIM: 601645) PREDICTED: serine/thre ( 479) 1964 424.0 4.4e-118
XP_016876911 (OMIM: 601645) PREDICTED: serine/thre ( 497) 1958 422.8 1.1e-117
XP_016876913 (OMIM: 601645) PREDICTED: serine/thre ( 410) 1835 396.8 6e-110
XP_005267884 (OMIM: 601645) PREDICTED: serine/thre ( 449) 1835 396.8 6.5e-110
XP_011535222 (OMIM: 601645) PREDICTED: serine/thre ( 449) 1835 396.8 6.5e-110
NP_001257405 (OMIM: 601646,616355) serine/threonin ( 451) 1824 394.5 3.3e-109
>>NP_006237 (OMIM: 601647) serine/threonine-protein phos (467 aa)
initn: 3077 init1: 3077 opt: 3077 Z-score: 3510.7 bits: 658.9 E(85289): 8.2e-189
Smith-Waterman score: 3077; 100.0% identity (100.0% similar) in 467 aa overlap (1-467:1-467)
10 20 30 40 50 60
pF1KE5 MSSAPTTPPSVDKVDGFSRKSVRKARQKRSQSSSQFRSQGKPIELTPLPLLKDVPSSEQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MSSAPTTPPSVDKVDGFSRKSVRKARQKRSQSSSQFRSQGKPIELTPLPLLKDVPSSEQP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 ELFLKKLQQCCVIFDFMDTLSDLKMKEYKRSTLNELVDYITISRGCLTEQTYPEVVRMVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 ELFLKKLQQCCVIFDFMDTLSDLKMKEYKRSTLNELVDYITISRGCLTEQTYPEVVRMVS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 CNIFRTLPPSDSNEFDPEEDEPTLEASWPHLQLVYEFFIRFLESQEFQPSIAKKYIDQKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 CNIFRTLPPSDSNEFDPEEDEPTLEASWPHLQLVYEFFIRFLESQEFQPSIAKKYIDQKF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 VLQLLELFDSEDPRERDYLKTVLHRIYGKFLGLRAFIRKQINNIFLRFVYETEHFNGVAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 VLQLLELFDSEDPRERDYLKTVLHRIYGKFLGLRAFIRKQINNIFLRFVYETEHFNGVAE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 LLEILGSIINGFALPLKAEHKQFLVKVLIPLHTVRSLSLFHAQLAYCIVQFLEKDPSLTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 LLEILGSIINGFALPLKAEHKQFLVKVLIPLHTVRSLSLFHAQLAYCIVQFLEKDPSLTE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE5 PVIRGLMKFWPKTCSQKEVMFLGELEEILDVIEPSQFVKIQEPLFKQIAKCVSSPHFQVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 PVIRGLMKFWPKTCSQKEVMFLGELEEILDVIEPSQFVKIQEPLFKQIAKCVSSPHFQVA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE5 ERALYYWNNEYIMSLIEENSNVILPIMFSSLYRISKEHWNPAIVALVYNVLKAFMEMNST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 ERALYYWNNEYIMSLIEENSNVILPIMFSSLYRISKEHWNPAIVALVYNVLKAFMEMNST
370 380 390 400 410 420
430 440 450 460
pF1KE5 MFDELTATYKSDRQREKKKEKEREELWKKLEDLELKRGLRRDGIIPT
:::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MFDELTATYKSDRQREKKKEKEREELWKKLEDLELKRGLRRDGIIPT
430 440 450 460
>>NP_001269108 (OMIM: 601647) serine/threonine-protein p (467 aa)
initn: 3077 init1: 3077 opt: 3077 Z-score: 3510.7 bits: 658.9 E(85289): 8.2e-189
Smith-Waterman score: 3077; 100.0% identity (100.0% similar) in 467 aa overlap (1-467:1-467)
10 20 30 40 50 60
pF1KE5 MSSAPTTPPSVDKVDGFSRKSVRKARQKRSQSSSQFRSQGKPIELTPLPLLKDVPSSEQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSSAPTTPPSVDKVDGFSRKSVRKARQKRSQSSSQFRSQGKPIELTPLPLLKDVPSSEQP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 ELFLKKLQQCCVIFDFMDTLSDLKMKEYKRSTLNELVDYITISRGCLTEQTYPEVVRMVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELFLKKLQQCCVIFDFMDTLSDLKMKEYKRSTLNELVDYITISRGCLTEQTYPEVVRMVS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 CNIFRTLPPSDSNEFDPEEDEPTLEASWPHLQLVYEFFIRFLESQEFQPSIAKKYIDQKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CNIFRTLPPSDSNEFDPEEDEPTLEASWPHLQLVYEFFIRFLESQEFQPSIAKKYIDQKF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 VLQLLELFDSEDPRERDYLKTVLHRIYGKFLGLRAFIRKQINNIFLRFVYETEHFNGVAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLQLLELFDSEDPRERDYLKTVLHRIYGKFLGLRAFIRKQINNIFLRFVYETEHFNGVAE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 LLEILGSIINGFALPLKAEHKQFLVKVLIPLHTVRSLSLFHAQLAYCIVQFLEKDPSLTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLEILGSIINGFALPLKAEHKQFLVKVLIPLHTVRSLSLFHAQLAYCIVQFLEKDPSLTE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE5 PVIRGLMKFWPKTCSQKEVMFLGELEEILDVIEPSQFVKIQEPLFKQIAKCVSSPHFQVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PVIRGLMKFWPKTCSQKEVMFLGELEEILDVIEPSQFVKIQEPLFKQIAKCVSSPHFQVA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE5 ERALYYWNNEYIMSLIEENSNVILPIMFSSLYRISKEHWNPAIVALVYNVLKAFMEMNST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ERALYYWNNEYIMSLIEENSNVILPIMFSSLYRISKEHWNPAIVALVYNVLKAFMEMNST
370 380 390 400 410 420
430 440 450 460
pF1KE5 MFDELTATYKSDRQREKKKEKEREELWKKLEDLELKRGLRRDGIIPT
:::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MFDELTATYKSDRQREKKKEKEREELWKKLEDLELKRGLRRDGIIPT
430 440 450 460
>>NP_001269109 (OMIM: 601647) serine/threonine-protein p (462 aa)
initn: 2870 init1: 2843 opt: 3017 Z-score: 3442.4 bits: 646.3 E(85289): 5.3e-185
Smith-Waterman score: 3017; 98.7% identity (98.9% similar) in 467 aa overlap (1-467:1-462)
10 20 30 40 50 60
pF1KE5 MSSAPTTPPSVDKVDGFSRKSVRKARQKRSQSSSQFRSQGKPIELTPLPLLKDVPSSEQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSSAPTTPPSVDKVDGFSRKSVRKARQKRSQSSSQFRSQGKPIELTPLPLLKDVPSSEQP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 ELFLKKLQQCCVIFDFMDTLSDLKMKEYKRSTLNELVDYITISRGCLTEQTYPEVVRMVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELFLKKLQQCCVIFDFMDTLSDLKMKEYKRSTLNELVDYITISRGCLTEQTYPEVVRMVS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 CNIFRTLPPSDSNEFDPEEDEPTLEASWPHLQLVYEFFIRFLESQEFQPSIAKKYIDQKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CNIFRTLPPSDSNEFDPEEDEPTLEASWPHLQLVYEFFIRFLESQEFQPSIAKKYIDQKF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 VLQLLELFDSEDPRERDYLKTVLHRIYGKFLGLRAFIRKQINNIFLRFVYETEHFNGVAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLQLLELFDSEDPRERDYLKTVLHRIYGKFLGLRAFIRKQINNIFLRFVYETEHFNGVAE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 LLEILGSIINGFALPLKAEHKQFLVKVLIPLHTVRSLSLFHAQLAYCIVQFLEKDPSLTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLEILGSIINGFALPLKAEHKQFLVKVLIPLHTVRSLSLFHAQLAYCIVQFLEKDPSLTE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE5 PVIRGLMKFWPKTCSQKEVMFLGELEEILDVIEPSQFVKIQEPLFKQIAKCVSSPHFQVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PVIRGLMKFWPKTCSQKEVMFLGELEEILDVIEPSQFVKIQEPLFKQIAKCVSSPHFQVA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE5 ERALYYWNNEYIMSLIEENSNVILPIMFSSLYRISKEHWNPAIVALVYNVLKAFMEMNST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ERALYYWNNEYIMSLIEENSNVILPIMFSSLYRISKEHWNPAIVALVYNVLKAFMEMNST
370 380 390 400 410 420
430 440 450 460
pF1KE5 MFDELTATYKSDRQREKKKEKEREELWKKLEDLELKRGLRRDGIIPT
:::::::::. ::::::::::::::::::::::::::::::::
NP_001 MFDELTATYN-----EKKKEKEREELWKKLEDLELKRGLRRDGIIPT
430 440 450 460
>>NP_001269110 (OMIM: 601647) serine/threonine-protein p (391 aa)
initn: 2571 init1: 2571 opt: 2571 Z-score: 2934.7 bits: 552.1 E(85289): 1e-156
Smith-Waterman score: 2571; 100.0% identity (100.0% similar) in 391 aa overlap (77-467:1-391)
50 60 70 80 90 100
pF1KE5 PLPLLKDVPSSEQPELFLKKLQQCCVIFDFMDTLSDLKMKEYKRSTLNELVDYITISRGC
::::::::::::::::::::::::::::::
NP_001 MDTLSDLKMKEYKRSTLNELVDYITISRGC
10 20 30
110 120 130 140 150 160
pF1KE5 LTEQTYPEVVRMVSCNIFRTLPPSDSNEFDPEEDEPTLEASWPHLQLVYEFFIRFLESQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LTEQTYPEVVRMVSCNIFRTLPPSDSNEFDPEEDEPTLEASWPHLQLVYEFFIRFLESQE
40 50 60 70 80 90
170 180 190 200 210 220
pF1KE5 FQPSIAKKYIDQKFVLQLLELFDSEDPRERDYLKTVLHRIYGKFLGLRAFIRKQINNIFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FQPSIAKKYIDQKFVLQLLELFDSEDPRERDYLKTVLHRIYGKFLGLRAFIRKQINNIFL
100 110 120 130 140 150
230 240 250 260 270 280
pF1KE5 RFVYETEHFNGVAELLEILGSIINGFALPLKAEHKQFLVKVLIPLHTVRSLSLFHAQLAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RFVYETEHFNGVAELLEILGSIINGFALPLKAEHKQFLVKVLIPLHTVRSLSLFHAQLAY
160 170 180 190 200 210
290 300 310 320 330 340
pF1KE5 CIVQFLEKDPSLTEPVIRGLMKFWPKTCSQKEVMFLGELEEILDVIEPSQFVKIQEPLFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CIVQFLEKDPSLTEPVIRGLMKFWPKTCSQKEVMFLGELEEILDVIEPSQFVKIQEPLFK
220 230 240 250 260 270
350 360 370 380 390 400
pF1KE5 QIAKCVSSPHFQVAERALYYWNNEYIMSLIEENSNVILPIMFSSLYRISKEHWNPAIVAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QIAKCVSSPHFQVAERALYYWNNEYIMSLIEENSNVILPIMFSSLYRISKEHWNPAIVAL
280 290 300 310 320 330
410 420 430 440 450 460
pF1KE5 VYNVLKAFMEMNSTMFDELTATYKSDRQREKKKEKEREELWKKLEDLELKRGLRRDGIIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VYNVLKAFMEMNSTMFDELTATYKSDRQREKKKEKEREELWKKLEDLELKRGLRRDGIIP
340 350 360 370 380 390
pF1KE5 T
:
NP_001 T
>>NP_001269111 (OMIM: 601647) serine/threonine-protein p (391 aa)
initn: 2571 init1: 2571 opt: 2571 Z-score: 2934.7 bits: 552.1 E(85289): 1e-156
Smith-Waterman score: 2571; 100.0% identity (100.0% similar) in 391 aa overlap (77-467:1-391)
50 60 70 80 90 100
pF1KE5 PLPLLKDVPSSEQPELFLKKLQQCCVIFDFMDTLSDLKMKEYKRSTLNELVDYITISRGC
::::::::::::::::::::::::::::::
NP_001 MDTLSDLKMKEYKRSTLNELVDYITISRGC
10 20 30
110 120 130 140 150 160
pF1KE5 LTEQTYPEVVRMVSCNIFRTLPPSDSNEFDPEEDEPTLEASWPHLQLVYEFFIRFLESQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LTEQTYPEVVRMVSCNIFRTLPPSDSNEFDPEEDEPTLEASWPHLQLVYEFFIRFLESQE
40 50 60 70 80 90
170 180 190 200 210 220
pF1KE5 FQPSIAKKYIDQKFVLQLLELFDSEDPRERDYLKTVLHRIYGKFLGLRAFIRKQINNIFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FQPSIAKKYIDQKFVLQLLELFDSEDPRERDYLKTVLHRIYGKFLGLRAFIRKQINNIFL
100 110 120 130 140 150
230 240 250 260 270 280
pF1KE5 RFVYETEHFNGVAELLEILGSIINGFALPLKAEHKQFLVKVLIPLHTVRSLSLFHAQLAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RFVYETEHFNGVAELLEILGSIINGFALPLKAEHKQFLVKVLIPLHTVRSLSLFHAQLAY
160 170 180 190 200 210
290 300 310 320 330 340
pF1KE5 CIVQFLEKDPSLTEPVIRGLMKFWPKTCSQKEVMFLGELEEILDVIEPSQFVKIQEPLFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CIVQFLEKDPSLTEPVIRGLMKFWPKTCSQKEVMFLGELEEILDVIEPSQFVKIQEPLFK
220 230 240 250 260 270
350 360 370 380 390 400
pF1KE5 QIAKCVSSPHFQVAERALYYWNNEYIMSLIEENSNVILPIMFSSLYRISKEHWNPAIVAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QIAKCVSSPHFQVAERALYYWNNEYIMSLIEENSNVILPIMFSSLYRISKEHWNPAIVAL
280 290 300 310 320 330
410 420 430 440 450 460
pF1KE5 VYNVLKAFMEMNSTMFDELTATYKSDRQREKKKEKEREELWKKLEDLELKRGLRRDGIIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VYNVLKAFMEMNSTMFDELTATYKSDRQREKKKEKEREELWKKLEDLELKRGLRRDGIIP
340 350 360 370 380 390
pF1KE5 T
:
NP_001 T
>>NP_006234 (OMIM: 601643) serine/threonine-protein phos (486 aa)
initn: 2484 init1: 2409 opt: 2477 Z-score: 2826.1 bits: 532.3 E(85289): 1.1e-150
Smith-Waterman score: 2477; 80.0% identity (94.7% similar) in 451 aa overlap (12-461:19-469)
10 20 30 40 50
pF1KE5 MSSAPTTPPSVDKVDGFSRKSVRKA-RQKRSQSSSQFRSQGKPIELTPLPLLK
.:::::.::::::: ::::::.::::::::. :: ::: ::
NP_006 MSSSSPPAGAASAAISASEKVDGFTRKSVRKAQRQKRSQGSSQFRSQGSQAELHPLPQLK
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE5 DVPSSEQPELFLKKLQQCCVIFDFMDTLSDLKMKEYKRSTLNELVDYITISRGCLTEQTY
:. :.:: ::: .::::::..:::::..:::: :: ::.::::::.:.. .:: ..:..:
NP_006 DATSNEQQELFCQKLQQCCILFDFMDSVSDLKSKEIKRATLNELVEYVSTNRGVIVESAY
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE5 PEVVRMVSCNIFRTLPPSDSNEFDPEEDEPTLEASWPHLQLVYEFFIRFLESQEFQPSIA
..:.:.: ::::::::::. .::::::::::::::::.:::::::.::::: .::::::
NP_006 SDIVKMISANIFRTLPPSDNPDFDPEEDEPTLEASWPHIQLVYEFFLRFLESPDFQPSIA
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE5 KKYIDQKFVLQLLELFDSEDPRERDYLKTVLHRIYGKFLGLRAFIRKQINNIFLRFVYET
:.::::::: :::::::::::::::.::::::::::::::::::::::::::::::.:::
NP_006 KRYIDQKFVQQLLELFDSEDPRERDFLKTVLHRIYGKFLGLRAFIRKQINNIFLRFIYET
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE5 EHFNGVAELLEILGSIINGFALPLKAEHKQFLVKVLIPLHTVRSLSLFHAQLAYCIVQFL
::::::::::::::::::::::::::::::::.:::::.::...:.:::::::::.::::
NP_006 EHFNGVAELLEILGSIINGFALPLKAEHKQFLMKVLIPMHTAKGLALFHAQLAYCVVQFL
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE5 EKDPSLTEPVIRGLMKFWPKTCSQKEVMFLGELEEILDVIEPSQFVKIQEPLFKQIAKCV
::: .:::::::::.:::::::::::::::::.:::::::::.:: ::.:::::::.:::
NP_006 EKDTTLTEPVIRGLLKFWPKTCSQKEVMFLGEIEEILDVIEPTQFKKIEEPLFKQISKCV
310 320 330 340 350 360
360 370 380 390 400 410
pF1KE5 SSPHFQVAERALYYWNNEYIMSLIEENSNVILPIMFSSLYRISKEHWNPAIVALVYNVLK
:: ::::::::::.::::::.:::::: . ::::::.:::.::::::::.::::::::::
NP_006 SSSHFQVAERALYFWNNEYILSLIEENIDKILPIMFASLYKISKEHWNPTIVALVYNVLK
370 380 390 400 410 420
420 430 440 450 460
pF1KE5 AFMEMNSTMFDELTATYKSDRQREKKKEKEREELWKKLEDLELKRGLRRDGIIPT
..::::. .::.::..::..:::::::: ::::::::::.:.::..:..
NP_006 TLMEMNGKLFDDLTSSYKAERQREKKKELEREELWKKLEELKLKKALEKQNSAYNMHSIL
430 440 450 460 470 480
NP_006 SNTSAE
>>NP_006235 (OMIM: 601644) serine/threonine-protein phos (497 aa)
initn: 2336 init1: 2336 opt: 2352 Z-score: 2683.3 bits: 505.9 E(85289): 1e-142
Smith-Waterman score: 2352; 73.8% identity (92.1% similar) in 454 aa overlap (4-457:20-471)
10 20 30 40
pF1KE5 MSSAPTTPPSVDKVDGFSRKSVRKARQKRSQSSSQFRSQGKPIE
.:. :: ::::::::.:.:.:: .::.:::::: :.. :
NP_006 METKLPPASTPTSPSSPGLSPVPPP--DKVDGFSRRSLRRARPRRSHSSSQFRYQSNQQE
10 20 30 40 50
50 60 70 80 90 100
pF1KE5 LTPLPLLKDVPSSEQPELFLKKLQQCCVIFDFMDTLSDLKMKEYKRSTLNELVDYITISR
:::::::::::.:: ::. .:: :: :.:::.: ..::: :: ::..:::::. . .:
NP_006 LTPLPLLKDVPASELHELLSRKLAQCGVMFDFLDCVADLKGKEVKRAALNELVECVGSTR
60 70 80 90 100 110
110 120 130 140 150 160
pF1KE5 GCLTEQTYPEVVRMVSCNIFRTLPPSDSNEFDPEEDEPTLEASWPHLQLVYEFFIRFLES
: : : .::...::.: :::::::::.. :::::::::.:: ::::::::::::.:::::
NP_006 GVLIEPVYPDIIRMISVNIFRTLPPSENPEFDPEEDEPNLEPSWPHLQLVYEFFLRFLES
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE5 QEFQPSIAKKYIDQKFVLQLLELFDSEDPRERDYLKTVLHRIYGKFLGLRAFIRKQINNI
.::::.::.:.::::::.:::::::::::::.::::.:::.:::::::::.:::: :.:
NP_006 PDFQPSVAKRYVDQKFVLMLLELFDSEDPREREYLKTILHRVYGKFLGLRAYIRKQCNHI
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE5 FLRFVYETEHFNGVAELLEILGSIINGFALPLKAEHKQFLVKVLIPLHTVRSLSLFHAQL
::::.:: :::::::::::::::::::::::::.:::::::.::::::.:.:::.:::::
NP_006 FLRFIYEFEHFNGVAELLEILGSIINGFALPLKTEHKQFLVRVLIPLHSVKSLSVFHAQL
240 250 260 270 280 290
290 300 310 320 330 340
pF1KE5 AYCIVQFLEKDPSLTEPVIRGLMKFWPKTCSQKEVMFLGELEEILDVIEPSQFVKIQEPL
:::.::::::: .::: :::::.:.:::::.:::::::::.:::::::::::::::::::
NP_006 AYCVVQFLEKDATLTEHVIRGLLKYWPKTCTQKEVMFLGEMEEILDVIEPSQFVKIQEPL
300 310 320 330 340 350
350 360 370 380 390 400
pF1KE5 FKQIAKCVSSPHFQVAERALYYWNNEYIMSLIEENSNVILPIMFSSLYRISKEHWNPAIV
:::.:.:::::::::::::::.::::::.::::.: ...:: .:..::..:::::: .::
NP_006 FKQVARCVSSPHFQVAERALYFWNNEYILSLIEDNCHTVLPAVFGTLYQVSKEHWNQTIV
360 370 380 390 400 410
410 420 430 440 450 460
pF1KE5 ALVYNVLKAFMEMNSTMFDELTATYKSDRQREKKKEKEREELWKKLEDLELKRGLRRDGI
.:.:::::.:::::. .::::::.:: ..:.:..: .::.:::. ::.:.:.:
NP_006 SLIYNVLKTFMEMNGKLFDELTASYKLEKQQEQQKAQERQELWQGLEELRLRRLQGTQGA
420 430 440 450 460 470
pF1KE5 IPT
NP_006 KEAPLQRLTPQVAASGGQS
480 490
>>NP_001186685 (OMIM: 601643) serine/threonine-protein p (429 aa)
initn: 2289 init1: 2264 opt: 2274 Z-score: 2595.3 bits: 489.4 E(85289): 8e-138
Smith-Waterman score: 2274; 79.4% identity (95.1% similar) in 412 aa overlap (50-461:1-412)
20 30 40 50 60 70
pF1KE5 KSVRKARQKRSQSSSQFRSQGKPIELTPLPLLKDVPSSEQPELFLKKLQQCCVIFDFMDT
.. .. :.:: ::: .::::::..:::::.
NP_001 MIMNATSNEQQELFCQKLQQCCILFDFMDS
10 20 30
80 90 100 110 120 130
pF1KE5 LSDLKMKEYKRSTLNELVDYITISRGCLTEQTYPEVVRMVSCNIFRTLPPSDSNEFDPEE
.:::: :: ::.::::::.:.. .:: ..:..: ..:.:.: ::::::::::. .:::::
NP_001 VSDLKSKEIKRATLNELVEYVSTNRGVIVESAYSDIVKMISANIFRTLPPSDNPDFDPEE
40 50 60 70 80 90
140 150 160 170 180 190
pF1KE5 DEPTLEASWPHLQLVYEFFIRFLESQEFQPSIAKKYIDQKFVLQLLELFDSEDPRERDYL
:::::::::::.:::::::.::::: .:::::::.::::::: :::::::::::::::.:
NP_001 DEPTLEASWPHIQLVYEFFLRFLESPDFQPSIAKRYIDQKFVQQLLELFDSEDPRERDFL
100 110 120 130 140 150
200 210 220 230 240 250
pF1KE5 KTVLHRIYGKFLGLRAFIRKQINNIFLRFVYETEHFNGVAELLEILGSIINGFALPLKAE
:::::::::::::::::::::::::::::.::::::::::::::::::::::::::::::
NP_001 KTVLHRIYGKFLGLRAFIRKQINNIFLRFIYETEHFNGVAELLEILGSIINGFALPLKAE
160 170 180 190 200 210
260 270 280 290 300 310
pF1KE5 HKQFLVKVLIPLHTVRSLSLFHAQLAYCIVQFLEKDPSLTEPVIRGLMKFWPKTCSQKEV
:::::.:::::.::...:.:::::::::.::::::: .:::::::::.::::::::::::
NP_001 HKQFLMKVLIPMHTAKGLALFHAQLAYCVVQFLEKDTTLTEPVIRGLLKFWPKTCSQKEV
220 230 240 250 260 270
320 330 340 350 360 370
pF1KE5 MFLGELEEILDVIEPSQFVKIQEPLFKQIAKCVSSPHFQVAERALYYWNNEYIMSLIEEN
:::::.:::::::::.:: ::.:::::::.::::: ::::::::::.::::::.::::::
NP_001 MFLGEIEEILDVIEPTQFKKIEEPLFKQISKCVSSSHFQVAERALYFWNNEYILSLIEEN
280 290 300 310 320 330
380 390 400 410 420 430
pF1KE5 SNVILPIMFSSLYRISKEHWNPAIVALVYNVLKAFMEMNSTMFDELTATYKSDRQREKKK
. ::::::.:::.::::::::.::::::::::..::::. .::.::..::..:::::::
NP_001 IDKILPIMFASLYKISKEHWNPTIVALVYNVLKTLMEMNGKLFDDLTSSYKAERQREKKK
340 350 360 370 380 390
440 450 460
pF1KE5 EKEREELWKKLEDLELKRGLRRDGIIPT
: ::::::::::.:.::..:..
NP_001 ELEREELWKKLEELKLKKALEKQNSAYNMHSILSNTSAE
400 410 420
>>XP_011543434 (OMIM: 601644) PREDICTED: serine/threonin (468 aa)
initn: 2262 init1: 2262 opt: 2267 Z-score: 2586.8 bits: 488.0 E(85289): 2.4e-137
Smith-Waterman score: 2267; 73.5% identity (92.2% similar) in 438 aa overlap (20-457:5-442)
10 20 30 40 50 60
pF1KE5 MSSAPTTPPSVDKVDGFSRKSVRKARQKRSQSSSQFRSQGKPIELTPLPLLKDVPSSEQP
.. ..:: .::.:::::: :.. ::::::::::::.::
XP_011 MGDFRNSHRARPRRSHSSSQFRYQSNQQELTPLPLLKDVPASELH
10 20 30 40
70 80 90 100 110 120
pF1KE5 ELFLKKLQQCCVIFDFMDTLSDLKMKEYKRSTLNELVDYITISRGCLTEQTYPEVVRMVS
::. .:: :: :.:::.: ..::: :: ::..:::::. . .:: : : .::...::.:
XP_011 ELLSRKLAQCGVMFDFLDCVADLKGKEVKRAALNELVECVGSTRGVLIEPVYPDIIRMIS
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE5 CNIFRTLPPSDSNEFDPEEDEPTLEASWPHLQLVYEFFIRFLESQEFQPSIAKKYIDQKF
:::::::::.. :::::::::.:: ::::::::::::.::::: .::::.::.:.::::
XP_011 VNIFRTLPPSENPEFDPEEDEPNLEPSWPHLQLVYEFFLRFLESPDFQPSVAKRYVDQKF
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE5 VLQLLELFDSEDPRERDYLKTVLHRIYGKFLGLRAFIRKQINNIFLRFVYETEHFNGVAE
::.:::::::::::::.::::.:::.:::::::::.:::: :.:::::.:: ::::::::
XP_011 VLMLLELFDSEDPREREYLKTILHRVYGKFLGLRAYIRKQCNHIFLRFIYEFEHFNGVAE
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE5 LLEILGSIINGFALPLKAEHKQFLVKVLIPLHTVRSLSLFHAQLAYCIVQFLEKDPSLTE
:::::::::::::::::.:::::::.::::::.:.:::.::::::::.::::::: .:::
XP_011 LLEILGSIINGFALPLKTEHKQFLVRVLIPLHSVKSLSVFHAQLAYCVVQFLEKDATLTE
230 240 250 260 270 280
310 320 330 340 350 360
pF1KE5 PVIRGLMKFWPKTCSQKEVMFLGELEEILDVIEPSQFVKIQEPLFKQIAKCVSSPHFQVA
:::::.:.:::::.:::::::::.::::::::::::::::::::::.:.::::::::::
XP_011 HVIRGLLKYWPKTCTQKEVMFLGEMEEILDVIEPSQFVKIQEPLFKQVARCVSSPHFQVA
290 300 310 320 330 340
370 380 390 400 410 420
pF1KE5 ERALYYWNNEYIMSLIEENSNVILPIMFSSLYRISKEHWNPAIVALVYNVLKAFMEMNST
:::::.::::::.::::.: ...:: .:..::..:::::: .::.:.:::::.:::::.
XP_011 ERALYFWNNEYILSLIEDNCHTVLPAVFGTLYQVSKEHWNQTIVSLIYNVLKTFMEMNGK
350 360 370 380 390 400
430 440 450 460
pF1KE5 MFDELTATYKSDRQREKKKEKEREELWKKLEDLELKRGLRRDGIIPT
.::::::.:: ..:.:..: .::.:::. ::.:.:.:
XP_011 LFDELTASYKLEKQQEQQKAQERQELWQGLEELRLRRLQGTQGAKEAPLQRLTPQVAASG
410 420 430 440 450 460
XP_011 GQS
>>NP_006236 (OMIM: 601646,616355) serine/threonine-prote (602 aa)
initn: 1918 init1: 1699 opt: 2083 Z-score: 2375.2 bits: 449.2 E(85289): 1.5e-125
Smith-Waterman score: 2083; 68.4% identity (85.5% similar) in 456 aa overlap (3-453:60-512)
10 20 30
pF1KE5 MSSAPTTPPS-VDKVDGFSRKSVRKARQKRSQ
: : ::. ..:. . .. : ..: :
NP_006 GENTEEAQPQPQPQPQPQAQSQPPSSNKRPSNSTPPPTQLSKIKYSGGPQIVK--KERRQ
30 40 50 60 70 80
40 50 60 70 80 90
pF1KE5 SSSQFRSQGKPIELTPLPLLKDVPSSEQPELFLKKLQQCCVIFDFM-DTLSDLKMKEYKR
:::.: . .: :: :: ::: :..:. :::..::.::::.:::. : :::::.:: ::
NP_006 SSSRF-NLSKNRELQKLPALKDSPTQEREELFIQKLRQCCVLFDFVSDPLSDLKFKEVKR
90 100 110 120 130 140
100 110 120 130 140
pF1KE5 STLNELVDYITISRGCLTEQTYPEVVRMVSCNIFRTLPPSDS---NEFDPEEDEPTLEAS
. :::.:.::: :: .:: :::.: : : :.:::::::.. :::::::::::::.
NP_006 AGLNEMVEYITHSRDVVTEAIYPEAVTMFSVNLFRTLPPSSNPTGAEFDPEEDEPTLEAA
150 160 170 180 190 200
150 160 170 180 190 200
pF1KE5 WPHLQLVYEFFIRFLESQEFQPSIAKKYIDQKFVLQLLELFDSEDPRERDYLKTVLHRIY
:::::::::::.::::: .:::.:::::::::::: ::.:::::::::::.:::.:::::
NP_006 WPHLQLVYEFFLRFLESPDFQPNIAKKYIDQKFVLALLDLFDSEDPRERDFLKTILHRIY
210 220 230 240 250 260
210 220 230 240 250 260
pF1KE5 GKFLGLRAFIRKQINNIFLRFVYETEHFNGVAELLEILGSIINGFALPLKAEHKQFLVKV
::::::::.::.:::.:: ::.::::: ::.::::::::::::::::::: :::.::..:
NP_006 GKFLGLRAYIRRQINHIFYRFIYETEHHNGIAELLEILGSIINGFALPLKEEHKMFLIRV
270 280 290 300 310 320
270 280 290 300 310 320
pF1KE5 LIPLHTVRSLSLFHAQLAYCIVQFLEKDPSLTEPVIRGLMKFWPKTCSQKEVMFLGELEE
:.::: :.:::..: :::::.::::::. ::::::: ::.:::::: : ::::::.::::
NP_006 LLPLHKVKSLSVYHPQLAYCVVQFLEKESSLTEPVIVGLLKFWPKTHSPKEVMFLNELEE
330 340 350 360 370 380
330 340 350 360 370 380
pF1KE5 ILDVIEPSQFVKIQEPLFKQIAKCVSSPHFQVAERALYYWNNEYIMSLIEENSNVILPIM
::::::::.: :..::::.:.:::::::::::::::::::::::::::: .:. .::::
NP_006 ILDVIEPSEFSKVMEPLFRQLAKCVSSPHFQVAERALYYWNNEYIMSLISDNAARVLPIM
390 400 410 420 430 440
390 400 410 420 430 440
pF1KE5 FSSLYRISKEHWNPAIVALVYNVLKAFMEMNSTMFDELTATYKSDRQREKKKEKEREELW
: .::: :: ::: .: .:.::.:: :::::. .::. : ::...:. . . :::::.:
NP_006 FPALYRNSKSHWNKTIHGLIYNALKLFMEMNQKLFDDCTQQYKAEKQKGRFRMKEREEMW
450 460 470 480 490 500
450 460
pF1KE5 KKLEDLELKRGLRRDGIIPT
.:.:.:
NP_006 QKIEELARLNPQYPMFRAPPPLPPVYSMETETPTAEDIQLLKRTVETEAVQMLKDIKKEK
510 520 530 540 550 560
467 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 04:03:35 2016 done: Tue Nov 8 04:03:36 2016
Total Scan time: 6.510 Total Display time: 0.060
Function used was FASTA [36.3.4 Apr, 2011]