Result of FASTA (ccds) for
pFN21AE4559
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE4559, 684 aa
1>>>pF1KE4559 684 - 684 aa - 684 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 11.6198+/-0.00133; mu= -1.8470+/- 0.081
mean_var=688.1282+/-141.183, 0's: 0 Z-trim(115.6): 215 B-trim: 0 in 0/52
Lambda= 0.048892
statistics sampled from 15978 (16189) to 15978 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.735), E-opt: 0.2 (0.497), width: 16
Scan time: 4.870
The best scores are: opt bits E(32554)
CCDS13505.1 COL9A3 gene_id:1299|Hs108|chr20 ( 684) 5102 375.3 1.6e-103
CCDS450.1 COL9A2 gene_id:1298|Hs108|chr1 ( 689) 2422 186.3 1.3e-46
CCDS47447.1 COL9A1 gene_id:1297|Hs108|chr6 ( 678) 2394 184.3 4.9e-46
CCDS4971.1 COL9A1 gene_id:1297|Hs108|chr6 ( 921) 2368 182.7 2.1e-45
CCDS6376.1 COL22A1 gene_id:169044|Hs108|chr8 (1626) 1913 150.9 1.3e-35
CCDS8759.1 COL2A1 gene_id:1280|Hs108|chr12 (1418) 1851 146.5 2.5e-34
CCDS41778.1 COL2A1 gene_id:1280|Hs108|chr12 (1487) 1851 146.5 2.6e-34
CCDS75932.1 COL5A1 gene_id:1289|Hs108|chr9 (1838) 1838 145.7 5.6e-34
CCDS6982.1 COL5A1 gene_id:1289|Hs108|chr9 (1838) 1838 145.7 5.6e-34
CCDS33350.1 COL5A2 gene_id:1290|Hs108|chr2 (1499) 1833 145.2 6.3e-34
CCDS34682.1 COL1A2 gene_id:1278|Hs108|chr7 (1366) 1821 144.3 1.1e-33
CCDS11561.1 COL1A1 gene_id:1277|Hs108|chr17 (1464) 1774 141.1 1.1e-32
CCDS780.2 COL11A1 gene_id:1301|Hs108|chr1 (1690) 1773 141.1 1.3e-32
CCDS53348.1 COL11A1 gene_id:1301|Hs108|chr1 (1767) 1773 141.1 1.3e-32
CCDS778.1 COL11A1 gene_id:1301|Hs108|chr1 (1806) 1773 141.1 1.3e-32
CCDS35366.1 COL4A5 gene_id:1287|Hs108|chrX (1691) 1744 139.0 5.3e-32
CCDS6802.1 COL27A1 gene_id:85301|Hs108|chr9 (1860) 1735 138.5 8.6e-32
CCDS43452.1 COL11A2 gene_id:1302|Hs108|chr6 (1650) 1724 137.6 1.4e-31
CCDS9511.1 COL4A1 gene_id:1282|Hs108|chr13 (1669) 1722 137.5 1.5e-31
CCDS42829.1 COL4A3 gene_id:1285|Hs108|chr2 (1670) 1699 135.9 4.7e-31
CCDS2297.1 COL3A1 gene_id:1281|Hs108|chr2 (1466) 1693 135.3 5.9e-31
CCDS14543.1 COL4A5 gene_id:1287|Hs108|chrX (1685) 1694 135.5 6.1e-31
CCDS12222.1 COL5A3 gene_id:50509|Hs108|chr19 (1745) 1687 135.0 8.7e-31
CCDS41353.1 COL24A1 gene_id:255631|Hs108|chr1 (1714) 1655 132.8 4.1e-30
CCDS42828.1 COL4A4 gene_id:1286|Hs108|chr2 (1690) 1642 131.8 7.7e-30
CCDS41907.1 COL4A2 gene_id:1284|Hs108|chr13 (1712) 1607 129.4 4.3e-29
CCDS41297.1 COL16A1 gene_id:1307|Hs108|chr1 (1604) 1605 129.2 4.6e-29
CCDS14542.1 COL4A6 gene_id:1288|Hs108|chrX (1690) 1576 127.2 1.9e-28
CCDS14541.1 COL4A6 gene_id:1288|Hs108|chrX (1691) 1576 127.2 1.9e-28
CCDS76010.1 COL4A6 gene_id:1288|Hs108|chrX (1707) 1576 127.2 2e-28
CCDS55025.1 COL21A1 gene_id:81578|Hs108|chr6 ( 957) 1561 125.8 2.9e-28
CCDS83099.1 COL21A1 gene_id:81578|Hs108|chr6 ( 954) 1558 125.6 3.4e-28
CCDS76009.1 COL4A6 gene_id:1288|Hs108|chrX (1666) 1556 125.8 5.1e-28
CCDS76008.1 COL4A6 gene_id:1288|Hs108|chrX (1633) 1555 125.7 5.3e-28
CCDS2773.1 COL7A1 gene_id:1294|Hs108|chr3 (2944) 1436 117.7 2.5e-25
CCDS43258.1 COL25A1 gene_id:84570|Hs108|chr4 ( 654) 1287 106.2 1.6e-22
CCDS72756.1 COL8A2 gene_id:1296|Hs108|chr1 ( 638) 1283 105.9 1.9e-22
CCDS403.1 COL8A2 gene_id:1296|Hs108|chr1 ( 703) 1283 106.0 2e-22
CCDS7554.1 COL17A1 gene_id:1308|Hs108|chr10 (1497) 1272 105.7 5.2e-22
CCDS42971.1 COL18A1 gene_id:80781|Hs108|chr21 (1339) 1253 104.3 1.2e-21
CCDS42972.1 COL18A1 gene_id:80781|Hs108|chr21 (1519) 1253 104.3 1.3e-21
CCDS77643.1 COL18A1 gene_id:80781|Hs108|chr21 (1754) 1253 104.4 1.4e-21
CCDS43259.1 COL25A1 gene_id:84570|Hs108|chr4 ( 642) 1237 102.7 1.8e-21
CCDS58922.1 COL25A1 gene_id:84570|Hs108|chr4 ( 645) 1192 99.5 1.6e-20
CCDS44428.2 COL13A1 gene_id:1305|Hs108|chr10 ( 610) 1161 97.3 7.1e-20
CCDS4436.1 COL23A1 gene_id:91522|Hs108|chr5 ( 540) 1103 93.1 1.1e-18
CCDS2934.1 COL8A1 gene_id:1295|Hs108|chr3 ( 744) 1101 93.2 1.5e-18
CCDS4970.1 COL19A1 gene_id:1310|Hs108|chr6 (1142) 1033 88.6 5.3e-17
CCDS5105.1 COL10A1 gene_id:1300|Hs108|chr6 ( 680) 986 85.0 3.9e-16
CCDS13730.1 COL6A2 gene_id:1292|Hs108|chr21 ( 828) 926 80.9 8.2e-15
>>CCDS13505.1 COL9A3 gene_id:1299|Hs108|chr20 (684 aa)
initn: 5102 init1: 5102 opt: 5102 Z-score: 1972.2 bits: 375.3 E(32554): 1.6e-103
Smith-Waterman score: 5102; 100.0% identity (100.0% similar) in 684 aa overlap (1-684:1-684)
10 20 30 40 50 60
pF1KE4 MAGPRACAPLLLLLLLGELLAAAGAQRVGLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 MAGPRACAPLLLLLLLGELLAAAGAQRVGLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 PGPKGAPGKPGKPGEAGLPGLPGVDGLTGRDGPPGPKGAPGERGSLGPPGPPGLGGKGLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 PGPKGAPGKPGKPGEAGLPGLPGVDGLTGRDGPPGPKGAPGERGSLGPPGPPGLGGKGLP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 GPPGEAGVSGPPGGIGLRGPPGPSGLPGLPGPPGPPGPPGHPGVLPEGATDLQCPSICPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 GPPGEAGVSGPPGGIGLRGPPGPSGLPGLPGPPGPPGPPGHPGVLPEGATDLQCPSICPP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 GPPGPPGMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGLPGPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 GPPGPPGMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGLPGPL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 GPPGDRGPIGFRGPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAGPSGEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 GPPGDRGPIGFRGPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAGPSGEP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 GMPGKDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGELGEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 GMPGKDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGELGEA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 GPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQKGSMGDPGLPGPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 GPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQKGSMGDPGLPGPQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE4 GLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPSGLVGPKGESGSRGELGPKGTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 GLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPSGLVGPKGESGSRGELGPKGTQ
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE4 GPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGKEASEQRIRELCGGMISEQIAQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 GPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGKEASEQRIRELCGGMISEQIAQL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE4 AAHLRKPLAPGSIGRPGPAGPPGPPGPPGSIGHPGARGPPGYRGPTGELGDPGPRGNQGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 AAHLRKPLAPGSIGRPGPAGPPGPPGPPGSIGHPGARGPPGYRGPTGELGDPGPRGNQGD
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE4 RGDKGAAGAGLDGPEGDQGPQGPQGVPGTSKDGQDGAPGEPGPPGDPGLPGAIGAQGTPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 RGDKGAAGAGLDGPEGDQGPQGPQGVPGTSKDGQDGAPGEPGPPGDPGLPGAIGAQGTPG
610 620 630 640 650 660
670 680
pF1KE4 ICDTSACQGAVLGGVGEKSGSRSS
::::::::::::::::::::::::
CCDS13 ICDTSACQGAVLGGVGEKSGSRSS
670 680
>>CCDS450.1 COL9A2 gene_id:1298|Hs108|chr1 (689 aa)
initn: 3370 init1: 1317 opt: 2422 Z-score: 950.5 bits: 186.3 E(32554): 1.3e-46
Smith-Waterman score: 2422; 51.0% identity (65.8% similar) in 681 aa overlap (1-670:1-672)
10 20 30 40 50
pF1KE4 MAGPRACAPLLLLLLLGELLAAAGAQRVGLPG---PPGPPGPPGKPGQDGIDGEAGPPGL
::. : .: ::.:: .... : :: : :: ::::::::: ::.:::::. ::::
CCDS45 MAAATA-SPRSLLVLL-QVVVLALAQIRGPPGERGPPGPPGPPGVPGSDGIDGDNGPPGK
10 20 30 40 50
60 70 80 90 100 110
pF1KE4 PGPPGPKGAPGKPGKPGEAGLPGLPGVDGLTGRDGPPGPKGAPGERGSLGPPGPPGLGGK
::::::: ::: : : : ::.::::: : ::: : :: .:. : :::::: :
CCDS45 AGPPGPKGEPGKAGPDGP---DGKPGIDGLTGAKGEPGPMGIPGVKGQPGLPGPPGLPGP
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE4 GLPGPPGEAGVSGPPGGIGLRGPPGPSGLPGLPGPPGPPGPPGHPGVLP--EGATDLQCP
:. :::: : : :: ::.::: : : : ::::::: ::.::.. ::..:. ::
CCDS45 GFAGPPGPPGPVGLPGEIGIRGPKGDPGPDGPSGPPGPPGKPGRPGTIQGLEGSADFLCP
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE4 SICPPGPPGPPGMPGFKGPTGYKG---EQGEVGKDGEKGDPGPPGPAGLPGSVGLQGPRG
. :::: ::::. : :: .: .: . :. :: : ::: : : :.:: ::.:
CCDS45 TNCPPGMKGPPGLQGVKGHAGKRGILGDPGHQGKPGPKGDVGASGEQGIPGP---PGPQG
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE4 LRGLPGPLGPPGDRGPIGFRGPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPKGTPG
.:: :: :: :. :: :..: : :: : :..: ::: : : ::: : :: .: :
CCDS45 IRGYPGMAGPKGETGPHGYKGMVGAIGATGPPGEEGPRGPPGRAGEKGDEGSPGIRGPQG
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE4 VAGPSGEPGMPGKDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERG
..::.: : :: .:..:.:: :.:: ::. : :: : .:: :.::. :.:: :..:
CCDS45 ITGPKGATGPPGINGKDGTPGTPGMKGSAGQAGQPGSPGHQGLAGVPGQPGTKGGPGDQG
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE4 RAGELGEAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQKGSMG
. : : : :: :: :. : :: : : :. : : .:: : :: .: :: :: .:
CCDS45 EPGPQGLPGFSGPPGKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQGPKGEQG
360 370 380 390 400 410
420 430 440 450 460 470
pF1KE4 DPGLPGPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPSGLVGPKGESGSRG
::.:::::: : ::.: : .::.: : : ::::.::: : :: ::::..: ::
CCDS45 PPGIPGPQGLPGVKGDKGSPGKTGPRGKVGDPGVAGLPGEKGEKGESGEPGPKGQQGVRG
420 430 440 450 460 470
480 490 500 510 520 530
pF1KE4 ELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGKEASEQRIRELCGGM
: : : .: :. :::: :::::: :: : :::: :. :: :..:..:.: .. :
CCDS45 EPGYPGPSGDAGAPGVQGYPGPPGPRGLAGNRGVPGQPGRQGVEGRDATDQHIVDVALKM
480 490 500 510 520 530
540 550 560 570 580
pF1KE4 ISEQIAQLAAHLRKPLAPGSIGRPGPAGPPGPPGPPGSIG---HPGARGPPGYRGPTGEL
..::.:..:. .. : :..: :: ::::::: ::. : ::: :: :: : .:..
CCDS45 LQEQLAEVAVSAKRE-ALGAVGMMGPPGPPGPPGYPGKQGPHGHPGPRGVPGIVGAVGQI
540 550 560 570 580 590
590 600 610 620 630 640
pF1KE4 GDPGPRGNQGDRGDKGAAGAGLDGPEGDQGPQGPQGVPGTSKDGQDGAPGEPGPPGDPGL
:. ::.:..:..:: : .: : : : : : : :: . .:.:: : :: ::. :
CCDS45 GNTGPKGKRGEKGDPGEVGRGHPGMPGPPGIPGLPGRPGQAINGKDGDRGSPGAPGEAGR
600 610 620 630 640 650
650 660 670 680
pF1KE4 PGAIGAQGTPGICDTSACQGAVLGGVGEKSGSRSS
:: : : ::.:. .:: ::
CCDS45 PGLPGPVGLPGFCEPAACLGASAYASARLTEPGSIKGP
660 670 680
>>CCDS47447.1 COL9A1 gene_id:1297|Hs108|chr6 (678 aa)
initn: 3341 init1: 1808 opt: 2394 Z-score: 939.9 bits: 184.3 E(32554): 4.9e-46
Smith-Waterman score: 2394; 50.8% identity (66.1% similar) in 663 aa overlap (11-667:11-663)
10 20 30 40 50 60
pF1KE4 MAGPRACAPLLLLLLLGELLAAAGAQRVGLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGP
: ::::: : :: : :::::::::: :: :::::. :: : :::
CCDS47 MAWTARDRGALGLLLLGLCLCAAQRGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 PGPKGAPGKPGKPGEAGLPGLPGVDGLTGRDGPPGPKGAPGERGSLGPPGPPGLGGKGLP
::: : ::::: ::. :: ::.::::: :: :: :. :..: : :: :. :.:.:
CCDS47 PGPAGEPGKPGAPGK---PGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIP
70 80 90 100 110
130 140 150 160 170 180
pF1KE4 GPPGEAGVSGPPGGIGLRGPPGPSGLPGLPGPPGPPGPPGHPGVLPEGATDLQCPSICPP
:::: :..: :: .: :: : :: :::::::::: :.. : ::. :::
CCDS47 GPPGPPGTAGLPGELGRVGPVGD---PGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPP
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE4 GPPGPPGMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGLPGPL
: : ::.::..: : ::: :: :..:.::. : : : :. : : .::::. : .
CCDS47 GRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIV
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE4 GPPGDRGPIGFRGPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAGPSGEP
: :..: :. : :: : :: ::.:.::: : ::::: : : .: ::. ::.:.
CCDS47 GDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDT
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE4 GMPGKDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGELGEA
:.:: ::..:.::. : ::: :. : ::. : .::::.:: :.:: ::.: .: :.
CCDS47 GLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKP
300 310 320 330 340 350
370 380 390 400 410 420
pF1KE4 GPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQKGSMGDPGLPGPQ
: :. : ::. : ::: : : .: :. : :: :.::. : :. :: : ::::::
CCDS47 GQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPP
360 370 380 390 400 410
430 440 450 460 470 480
pF1KE4 GLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPSGLVGPKGESGSRGELGPKGTQ
:: : :::: : ::::.:: .: .: :..:::: :: :::: .:. :: : .: .
CCDS47 GLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPE
420 430 440 450 460 470
490 500 510 520 530 540
pF1KE4 GPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGKEASEQRIRELCGGMISEQIAQL
: : ::.: ::::: :.:: :. :. : : ::. ..:.:...: .:.:..:..
CCDS47 GSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEM
480 490 500 510 520 530
550 560 570 580 590
pF1KE4 AAHLRKPLAPGSIGRPGPAGPPGPPGPPGSIGHPGA---RGPPGYRGPTGELGDPGPRGN
:: :..: :. : :: :::::::::: : :: :: :: .:: : :: ::.:.
CCDS47 AASLKRP-DSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGD
540 550 560 570 580 590
600 610 620 630 640 650
pF1KE4 QGDRGDKGAAGAGLDGPEGDQGPQGPQGVPGTSKDGQDGAPGEPGPPGD---PGLPGAIG
:..:..: : : :.: : : : :: .. :..: :: :::: ::.:: :
CCDS47 LGEKGERGPPGRG---PNGLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPGPPG
600 610 620 630 640 650
660 670 680
pF1KE4 AQGTPGICDTSACQGAVLGGVGEKSGSRSS
: ::.:. ..:
CCDS47 PPGLPGFCEPASCTMQAGQRAFNKGPDP
660 670
>>CCDS4971.1 COL9A1 gene_id:1297|Hs108|chr6 (921 aa)
initn: 5409 init1: 1808 opt: 2368 Z-score: 928.6 bits: 182.7 E(32554): 2.1e-45
Smith-Waterman score: 2368; 50.9% identity (66.7% similar) in 645 aa overlap (29-667:272-906)
10 20 30 40 50
pF1KE4 MAGPRACAPLLLLLLLGELLAAAGAQRVGLPGPPGPPGPPGKPGQDGIDGEAGPPGLP
: :::::::::: :: :::::. :: : :
CCDS49 CDPLRPRRETCHELPARITPSQTTDERGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPP
250 260 270 280 290 300
60 70 80 90 100 110
pF1KE4 GPPGPKGAPGKPGKPGEAGLPGLPGVDGLTGRDGPPGPKGAPGERGSLGPPGPPGLGGKG
::::: : ::::: ::. :: ::.::::: :: :: :. :..: : :: :. :.:
CCDS49 GPPGPAGEPGKPGAPGK---PGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRG
310 320 330 340 350
120 130 140 150 160 170
pF1KE4 LPGPPGEAGVSGPPGGIGLRGPPGPSGLPGLPGPPGPPGPPGHPGVLPEGATDLQCPSIC
.::::: :..: :: .: :: : :: :::::::::: :.. : ::. :
CCDS49 IPGPPGPPGTAGLPGELGRVGPVGD---PGRRGPPGPPGPPGPRGTIGFHDGDPLCPNAC
360 370 380 390 400 410
180 190 200 210 220 230
pF1KE4 PPGPPGPPGMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGLPG
::: : ::.::..: : ::: :: :..:.::. : : : :. : : .::::. :
CCDS49 PPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITG
420 430 440 450 460 470
240 250 260 270 280 290
pF1KE4 PLGPPGDRGPIGFRGPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAGPSG
.: :..: :. : :: : :: ::.:.::: : ::::: : : .: ::. ::.:
CCDS49 IVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKG
480 490 500 510 520 530
300 310 320 330 340 350
pF1KE4 EPGMPGKDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGELG
. :.:: ::..:.::. : ::: :. : ::. : .::::.:: :.:: ::.: .: :
CCDS49 DTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPG
540 550 560 570 580 590
360 370 380 390 400 410
pF1KE4 EAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQKGSMGDPGLPG
. : :. : ::. : ::: : : .: :. : :: :.::. : :. :: : :::::
CCDS49 KPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPG
600 610 620 630 640 650
420 430 440 450 460 470
pF1KE4 PQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPSGLVGPKGESGSRGELGPKG
: :: : :::: : ::::.:: .: .: :..:::: :: :::: .:. :: : .:
CCDS49 PPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRG
660 670 680 690 700 710
480 490 500 510 520 530
pF1KE4 TQGPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGKEASEQRIRELCGGMISEQIA
.: : ::.: ::::: :.:: :. :. : : ::. ..:.:...: .:.:..:
CCDS49 PEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFA
720 730 740 750 760 770
540 550 560 570 580 590
pF1KE4 QLAAHLRKPLAPGSIGRPGPAGPPGPPGPPGSIGHPGA---RGPPGYRGPTGELGDPGPR
..:: :..: . :. : :: :::::::::: : :: :: :: .:: : :: ::.
CCDS49 EMAASLKRPDS-GATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPK
780 790 800 810 820 830
600 610 620 630 640 650
pF1KE4 GNQGDRGDKGAAGAGLDGPEGDQGPQGPQGVPGTSKDGQDGAPGEPGPPGD---PGLPGA
:. :..:..: : ::.: : : : :: .. :..: :: :::: ::.::
CCDS49 GDLGEKGERGPPGR---GPNGLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPGP
840 850 860 870 880 890
660 670 680
pF1KE4 IGAQGTPGICDTSACQGAVLGGVGEKSGSRSS
: : ::.:. ..:
CCDS49 PGPPGLPGFCEPASCTMQAGQRAFNKGPDP
900 910 920
>>CCDS6376.1 COL22A1 gene_id:169044|Hs108|chr8 (1626 aa)
initn: 3203 init1: 1217 opt: 1913 Z-score: 752.7 bits: 150.9 E(32554): 1.3e-35
Smith-Waterman score: 1949; 44.4% identity (56.1% similar) in 711 aa overlap (28-681:924-1622)
10 20 30 40
pF1KE4 MAGPRACAPLLLLLLLGELLAAAGAQRVGLPGPPGPPG----P-----PGKPGQDGI
:: ::: :::: : ::: :. :
CCDS63 QGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGE
900 910 920 930 940 950
50 60 70 80 90
pF1KE4 DGEAGPPGLPGPPGPKGAPGKPGKPGEAGLPGLPGVDGLTGRDGPPGP------------
: :: : ::: ::.: :: :: :: : : : :: : : :::
CCDS63 KGAAGEEGSPGPVGPRGDPGAPGLPGPPG-KGKDGEPGLRGSPGLPGPLGTKAACGKVRG
960 970 980 990 1000 1010
100 110 120 130
pF1KE4 --------------KGAPGERGSLGPPGPPGLGGKGLPGPPGEAGVSGPPGGIGLRG---
.:::: :: : : ::.: : ::: : : .: ::. :: :
CCDS63 SENCALGGQCVKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPG
1020 1030 1040 1050 1060 1070
140 150 160 170 180 190
pF1KE4 PPGPSGLPGLPGPPGPPGPPGHPGV---LPEGATDLQCPSIC---PPGPPGPPGMPGFKG
: ::.: : :: :: ::::.::. : : .: ..: :::::: ::.:::::
CCDS63 PQGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKG
1080 1090 1100 1110 1120 1130
200 210 220 230 240 250
pF1KE4 PTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGLPGPLGPPGDRG-P--IG
: :. :. : .:.::. :::: : :: .: :: .: :: : .: ::.: : :
CCDS63 DKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPG
1140 1150 1160 1170 1180 1190
260 270 280 290 300
pF1KE4 FRGPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAGPSGEPGMPG---KDG
: :::: :: :: : : :: :.. : :: .: :: :::: ::.:: :.:
CCDS63 FMGPPGNPGPPGADGIAGAAGPPGIQ------GSPGKEGPPGPQGPSGLPGIPGEEGKEG
1200 1210 1220 1230 1240
310 320 330 340 350 360
pF1KE4 QNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGELGEAGPSGEPG
..: :: :. :.::. : :: .: : ::. :..:..: : ::..: .: : : ::
CCDS63 RDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPG
1250 1260 1270 1280 1290 1300
370 380 390 400 410 420
pF1KE4 VPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQKGSMGDPGLPGPQGLRGDVG
::.: : .: : :: : : : :: :: : ::::: :. : :: :. : :
CCDS63 KDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRG
1310 1320 1330 1340 1350 1360
430 440 450 460 470 480
pF1KE4 DRGPGGAAGPKGDQGIAGSDGLPGDKGELGPSGLVGPKGESGSRGELGPKGTQGPNGTSG
: : : : .:. :. : :: ::: : :. : :: :..:. : : : .: .:
CCDS63 PPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTG
1370 1380 1390 1400 1410 1420
490 500 510 520 530 540
pF1KE4 V---QGVPGPPGPLGLQGVPGVPGITGKPG-VPGKEASEQRIRELCGGMISEQIAQLAAH
. ::.:: ::.: : :: ::. : : :. :. .. :.: : .. ..: : :.
CCDS63 LMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQ
1430 1440 1450 1460 1470 1480
550 560 570 580 590 600
pF1KE4 LRKPLAPGSIGRPGPAGPPGPPGPPGSIGHPGARGPPGYRGPTGELGDPGPRGNQGDRGD
. .: ::::: :::: : :: : : : :: : : : ::.:..: .::
CCDS63 MPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGD
1490 1500 1510 1520 1530 1540
610 620 630 640 650 660
pF1KE4 KGAAGAGLDGPEGDQGPQGPQGVPGTSKDGQDGAPG---EPGPPGDPGLPGAIGAQGTPG
:: :.:: : : : : : :: .::: : :: : :: : ::::: : ::
CCDS63 PGAPGVGLRGEMGPPGIPGQPGEPGYAKDGLPGIPGPQGETGPAGHPGLPGP---PGPPG
1550 1560 1570 1580 1590 1600
670 680
pF1KE4 ICDTSACQGAVLGGVGEKSGSRSS
:: : : : ..... . :.
CCDS63 QCDPSQC--AYFASLAARPGNVKGP
1610 1620
>--
initn: 1203 init1: 620 opt: 1337 Z-score: 533.1 bits: 110.3 E(32554): 2.3e-23
Smith-Waterman score: 1373; 47.1% identity (57.0% similar) in 512 aa overlap (31-517:451-922)
10 20 30 40
pF1KE4 MAGPRACAPLLLLLLLGELLAAAGAQRVGLPGPPGPPGPPGKPGQD--------------
: :: :: : ::..
CCDS63 IVIYCDSRHAELETCCDIPSGPCQVTVVTEPPPPPPPQRPPTPGSEQIGFLKTINCSCPA
430 440 450 460 470 480
50 60 70 80 90 100
pF1KE4 GIDGE---AGPPGLPGPPGPKGAPGKPGKPGEAGLPGLPGVDGLTGRDGPPGPKGAPGER
: :: ::: ::::: : :: : : :: : : :. :: : .: ::.
CCDS63 GEKGEMGVAGPMGLPGPKGDIGAIGPVGAPGPKGEKGDVGI-------GPFG-QGEKGEK
490 500 510 520 530
110 120 130 140 150 160
pF1KE4 GSLGPPGPPGL-GGKGLPGPPGEAGVSGPPGGIGLRGPPGPSGLPGLPGPPGPPGPPGHP
:::: ::::: :.::. : ::: : : :: .:.::: :: :::::::: : ::
CCDS63 GSLGLPGPPGRDGSKGMRGEPGELGEPGLPGEVGMRGPQGP---PGLPGPPGRVGAPGLQ
540 550 560 570 580
170 180 190 200 210 220
pF1KE4 GVLPEGATDLQCPSICPPGPPGPPGMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLP
: : .: . : : :: :: : : : .: .: .::::: :: :: :.:
CCDS63 GERGEKGTRGEKGE---RGLDGFPGKPGDTGQQGRPGPSGVAGPQGEKGDVGPAGPPGVP
590 600 610 620 630 640
230 240 250 260 270
pF1KE4 GSVGLQ-GPRGLRGLPGPLG------PPGDRGPIGFRGPPGIPGAPGKAGDRGERGPEGF
::: : : .: .: ::: : ::: ::::: .: : :: : : .:. :: :.
CCDS63 GSVVQQEGLKGEQGAPGPRGHQGAPGPPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPGI
650 660 670 680 690 700
280 290 300 310 320 330
pF1KE4 RGPKGDLGRPGPKGTPGVAGPSGEPGMPGKDGQNGVPGLDGQKGEAGRNGAPGEKGPNGL
: : : ::: :.:: ::.: ::.: :. : :: . : : .: ::. ::::
CCDS63 PGLLGLQGPPGPPGVPGPPGPGGSPGLP---GEIGFPG---KPGPPGPTGPPGKDGPNGP
710 720 730 740 750 760
340 350 360 370 380 390
pF1KE4 PGLPGRAGSKGEKGERGRAGELGEAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGP
:: :: .::: ::::. : :. : :: : : :: :::.:::: : :
CCDS63 PGPPG---TKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGL--------P-GA
770 780 790 800
400 410 420 430 440 450
pF1KE4 PGAPGVRGFQGQKGSMGDPGLPGPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGE
:: ::::: .:..: :. :::: :.:: :: : ::: : :. :. .: . .
CCDS63 PGFPGVRGEKGDQGEKGELGLPG---LKGD---RGEKGEAGPAGPPGLPGTTSLFTPHPR
810 820 830 840 850 860
460 470 480 490 500 510
pF1KE4 LGPSGLVGPKGESGSRGELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGV
. : : :::::.:. : : : :: : : :: :::: : .:. :.:: .:.::.
CCDS63 M-P-GEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGA
870 880 890 900 910 920
520 530 540 550 560 570
pF1KE4 PGKEASEQRIRELCGGMISEQIAQLAAHLRKPLAPGSIGRPGPAGPPGPPGPPGSIGHPG
::
CCDS63 PGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGP
930 940 950 960 970 980
>>CCDS8759.1 COL2A1 gene_id:1280|Hs108|chr12 (1418 aa)
initn: 1212 init1: 1212 opt: 1851 Z-score: 729.6 bits: 146.5 E(32554): 2.5e-34
Smith-Waterman score: 1916; 45.5% identity (54.4% similar) in 723 aa overlap (10-660:11-711)
10 20 30 40 50
pF1KE4 MAGPRACAPLLLLLLLGELLAAAGAQRVGLPGPPGPPGPPGKPGQDGIDGEAGPPGLPG
.:: ::.. .: : : : ::: : : :: : .:: : ::
CCDS87 MIRLGAPQTLVLLTLLVAAVLRCQG-QDVRQPGPKGQKGEPGD-----IKDIVGPKGPPG
10 20 30 40 50
60 70 80 90 100 110
pF1KE4 PPGPKGAPGKPGKPGEAGLPGLPGVDGLTGRDGPPGPKGAPGERGSLGPPGPPGLGGK--
: :: : : : :. : : :: :::: :: : :: : ::::::::::.
CCDS87 PQGPAGEQGPRGDRGDKGEKGAPGP---RGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFA
60 70 80 90 100 110
120 130 140 150
pF1KE4 ----G-------------LPGPPGEAGVSGPPGGIGLRGPPGPSGLPGLPGPPG------
: . :: : : :::: : :: : .: :: :: ::
CCDS87 AQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMG
120 130 140 150 160 170
160 170 180 190
pF1KE4 ---PPGPPGHPGVLPEGATDLQCPSICPPGP------PGPPGMPGFKGPTGY------KG
::::::.:: :.. . :::: :: ::.:: :: :: ::
CCDS87 PRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKG
180 190 200 210 220 230
200 210 220 230 240
pF1KE4 E------QGEVGKDGEKGDPGPPGPAGLPGSVGLQGP------RGLRGLPGPLGPPGDRG
: .:: :. ::.:.::: :: :::: : :: :: : ::: :::: :
CCDS87 EAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVG
240 250 260 270 280 290
250 260 270 280 290 300
pF1KE4 PIGFRGPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAGPSGEPGMPGKDG
: : : :: ::: :.:: : ::::: .::.:. : :::: ::.: : :: ::
CCDS87 PAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGE---P---GTPGSPGPAGASGNPGTDG
300 310 320 330 340
310 320 330 340 350 360
pF1KE4 QNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGELGEAGPSGEPG
:. : : : :: : :: .:: : : : : ::. :: : :: :: ::.::::
CCDS87 IPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPG
350 360 370 380 390 400
370 380 390 400 410 420
pF1KE4 VPGDAGMPGERGEAGHRGS---AGALGPQGPPG---APGVRGFQGQKGSMGDPGLPGPQG
: : :: :: :.::. :..:: :::: ::: ::: :: : : : :: .:
CCDS87 PAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERG
410 420 430 440 450 460
430 440 450 460 470 480
pF1KE4 LRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPSGLVGPKGESGSRGELGPKGTQG
: .: .: .: : :. :. :. :: : :. ::.: :::.: : :. :: : ::
CCDS87 PSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQG
470 480 490 500 510 520
490 500 510 520 530
pF1KE4 PNGTSGVQGVPGP------PGPLGLQGVPGVPGITGKPGVPGKEASEQRIRELCGGMISE
: ::.: ::: :: : .:.::.::. : :: :. .. .: .:
CCDS87 ARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGP--AGPAGE
530 540 550 560 570 580
540 550 560 570 580 590
pF1KE4 QIAQLAAHLRKPLAPGSIGRPGPAGPPGPPGPPGSIGHPGARGPPGYRGPTGELGDPGPR
. : : : : : ::: :::: : ::. : :: : :: :: :: : :: :
CCDS87 RGEQGA-----PGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGER
590 600 610 620 630
600 610 620 630 640
pF1KE4 GN---QGDRGDKGAAGA-GLDGPEGDQGPQGP---QGVPGTSK-DGQDGAPGEPGPPGDP
:. :: .: .: :. : :::.: .:: :: :: :: . :. :: : :: ::
CCDS87 GSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDR
640 650 660 670 680 690
650 660 670 680
pF1KE4 GLPGAIGAQGTPGICDTSACQGAVLGGVGEKSGSRSS
: : : .:.::
CCDS87 GDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGET
700 710 720 730 740 750
>--
initn: 1123 init1: 1123 opt: 1323 Z-score: 528.3 bits: 109.2 E(32554): 4.1e-23
Smith-Waterman score: 1433; 47.3% identity (57.2% similar) in 488 aa overlap (29-515:717-1149)
10 20 30 40 50
pF1KE4 MAGPRACAPLLLLLLLGELLAAAGAQRVGLPGPPGPPGPPGKPGQDGIDGEAGPPGLP
:: :: ::::: : :. : :.:::
CCDS87 GAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKG---EVGPP---
690 700 710 720 730 740
60 70 80 90 100 110
pF1KE4 GPPGPKGAPGKPGKPGEAGLPGLPGVDGLTGRDGPPGPKGAPGERGSLGPPGPPG-LGGK
:: : :: : ::. ::.: :: : : : :: :: :: :: :. : : :: : .
CCDS87 GPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPS
750 760 770 780 790 800
120 130 140 150 160 170
pF1KE4 GLPGPPGEAGVSGPPGGIGLRGPPGPSGLPGLPGPPGPPGPPGHPGVLPEGATDLQCPSI
: ::: : .::.:: :. : .:::: .:.:: : :::: :.::
CCDS87 GAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPG--------------
810 820 830 840
180 190 200 210 220 230
pF1KE4 CPPGPPGPPGMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGLP
::::::: : : :: .:: :::: :: : ::::: : :
CCDS87 -PPGPPGPSGKDGPKGA---------------RGDSGPPGRAGEP---GLQGPAGP---P
850 860 870 880
240 250 260 270 280 290
pF1KE4 GPLGPPGDRGPIGFRGPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAGPS
: : ::: :: : .:::: : : ::.:: : : :: .: : :::.: :: :
CCDS87 GEKGEPGDDGPSGAEGPPG-P--QGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAP
890 900 910 920 930 940
300 310 320 330 340 350
pF1KE4 GEPGMPGKDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGEL
: : : : : ::: : :: ::.:.:: :: ::: :. : ::.::..: .
CCDS87 GASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGP------PGRDGAAGVKGDRGETGAV
950 960 970 980 990
360 370 380 390 400 410
pF1KE4 GEAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQKGSMGDPGLP
: : : :: :: :: :..:. :. :. : .::.:: :: :..: :: .:. :. : :
CCDS87 GAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEP
1000 1010 1020 1030 1040 1050
420 430 440 450 460 470
pF1KE4 GPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPSGLVGPKGESGSRGELGPK
: .::.: : : : :: : .: :..: : .: :: : :::.:..:. : ::
CCDS87 GERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPI
1060 1070 1080 1090 1100 1110
480 490 500 510 520 530
pF1KE4 GTQGPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGKEASEQRIRELCGGMISEQI
: :: : :: : :::: : : :: :: ::.
CCDS87 GPPGPRGRSGETGPAGPPGNPGPPGPPGPPG----PGIDMSAFAGLGPREKGPDPLQYMR
1120 1130 1140 1150 1160 1170
540 550 560 570 580 590
pF1KE4 AQLAAHLRKPLAPGSIGRPGPAGPPGPPGPPGSIGHPGARGPPGYRGPTGELGDPGPRGN
CCDS87 ADQAAGGLRQHDAEVDATLKSLNNQIESIRSPEGSRKNPARTCRDLKLCHPEWKSGDYWI
1180 1190 1200 1210 1220 1230
>>CCDS41778.1 COL2A1 gene_id:1280|Hs108|chr12 (1487 aa)
initn: 1212 init1: 1212 opt: 1851 Z-score: 729.4 bits: 146.5 E(32554): 2.6e-34
Smith-Waterman score: 1911; 46.4% identity (55.5% similar) in 685 aa overlap (28-660:116-780)
10 20 30 40 50
pF1KE4 MAGPRACAPLLLLLLLGELLAAAGAQRVGLPGPPGPPGPPGKPGQDGIDGEAGPPGL
:: ::::: :: :. : : :. : :
CCDS41 CPICPTDLATASGQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGA
90 100 110 120 130 140
60 70 80 90
pF1KE4 PGPPGPKGAPGKPGKPGEAGLPGLPGVDGLTGR---------------------DGPPGP
::: : : :: ::.:: : :: :: :: : .:: ::
CCDS41 PGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGP
150 160 170 180 190 200
100 110 120 130 140 150
pF1KE4 KGAPGERGSLGPPGPPGLGGKGLPGPPGEAGVSGPPGGIGLRGPPGPSGLPGLPGPPGPP
: : : : ::: :. :. :: ::: ::::: .: :::::: : :: : : :
CCDS41 MGPRGPPGPAGAPGPQGFQGN--PGEPGEPGVSGP---MGPRGPPGPPGKPGDDGEAGKP
210 220 230 240 250 260
160 170 180 190 200 210
pF1KE4 GPPGH---PGVLPEGATDLQCPSICP--PGPPGPPGMPGFKGPTGYKGEQGEVGKDGEKG
: :. :: :.:: . : : : ::. : :: .: : .:: :. ::.:
CCDS41 GKAGERGPPG--PQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENG
270 280 290 300 310
220 230 240 250 260
pF1KE4 DPGPPGPAGLPGSVGLQGP------RGLRGLPGPLGPPGDRGPIGFRGPPGIPGAPGKAG
.::: :: :::: : :: :: : ::: :::: :: : : :: ::: :.::
CCDS41 SPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAG
320 330 340 350 360 370
270 280 290 300 310 320
pF1KE4 DRGERGPEGFRGPKGDLGRPGPKGTPGVAGPSGEPGMPGKDGQNGVPGLDGQKGEAGRNG
: ::::: .::.:. : :::: ::.: : :: :: :. : : : :: :
CCDS41 PTGARGPEGAQGPRGE-----P-GTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPG
380 390 400 410 420 430
330 340 350 360 370 380
pF1KE4 APGEKGPNGLPGLPGRAGSKGEKGERGRAGELGEAGPSGEPGVPGDAGMPGERGEAGHRG
:: .:: : : : : ::. :: : :: :: ::.:::: : : :: :: :.::
CCDS41 FPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRG
440 450 460 470 480 490
390 400 410 420 430
pF1KE4 S---AGALGPQGPPG---APGVRGFQGQKGSMGDPGLPGPQGLRGDVGDRGPGGAAGPKG
. :..:: :::: ::: ::: :: : : : :: .: : .: .: .: : :
CCDS41 ARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPG
500 510 520 530 540 550
440 450 460 470 480 490
pF1KE4 DQGIAGSDGLPGDKGELGPSGLVGPKGESGSRGELGPKGTQGPNGTSGVQGVPGP-----
. :. :. :: : :. ::.: :::.: : :. :: : :: : ::.: :::
CCDS41 EPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANG
560 570 580 590 600 610
500 510 520 530 540 550
pF1KE4 -PGPLGLQGVPGVPGITGKPGVPGKEASEQRIRELCGGMISEQIAQLAAHLRKPLAPGSI
:: : .:.::.::. : :: :. .. .: .:. : : : :
CCDS41 EPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGP--AGPAGERGEQGA-----PGPSGFQ
620 630 640 650 660
560 570 580 590 600
pF1KE4 GRPGPAGPPGPPGPPGSIGHPGARGPPGYRGPTGELGDPGPRGN---QGDRGDKGAAGA-
: ::: :::: : ::. : :: : :: :: :: : :: ::. :: .: .: :.
CCDS41 GLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTP
670 680 690 700 710 720
610 620 630 640 650 660
pF1KE4 GLDGPEGDQGPQGP---QGVPGTSK-DGQDGAPGEPGPPGDPGLPGAIGAQGTPGICDTS
: :::.: .:: :: :: :: . :. :: : :: :: : : : .:.::
CCDS41 GTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGR
730 740 750 760 770 780
670 680
pF1KE4 ACQGAVLGGVGEKSGSRSS
CCDS41 GLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQP
790 800 810 820 830 840
>--
initn: 1123 init1: 1123 opt: 1323 Z-score: 528.1 bits: 109.3 E(32554): 4.3e-23
Smith-Waterman score: 1433; 47.3% identity (57.2% similar) in 488 aa overlap (29-515:786-1218)
10 20 30 40 50
pF1KE4 MAGPRACAPLLLLLLLGELLAAAGAQRVGLPGPPGPPGPPGKPGQDGIDGEAGPPGLP
:: :: ::::: : :. : :.:::
CCDS41 GAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKG---EVGPP---
760 770 780 790 800
60 70 80 90 100 110
pF1KE4 GPPGPKGAPGKPGKPGEAGLPGLPGVDGLTGRDGPPGPKGAPGERGSLGPPGPPG-LGGK
:: : :: : ::. ::.: :: : : : :: :: :: :: :. : : :: : .
CCDS41 GPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPS
810 820 830 840 850 860
120 130 140 150 160 170
pF1KE4 GLPGPPGEAGVSGPPGGIGLRGPPGPSGLPGLPGPPGPPGPPGHPGVLPEGATDLQCPSI
: ::: : .::.:: :. : .:::: .:.:: : :::: :.::
CCDS41 GAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPG--------------
870 880 890 900 910
180 190 200 210 220 230
pF1KE4 CPPGPPGPPGMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGLP
::::::: : : :: .:: :::: :: : ::::: : :
CCDS41 -PPGPPGPSGKDGPKGA---------------RGDSGPPGRAGEP---GLQGPAGP---P
920 930 940 950
240 250 260 270 280 290
pF1KE4 GPLGPPGDRGPIGFRGPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAGPS
: : ::: :: : .:::: : : ::.:: : : :: .: : :::.: :: :
CCDS41 GEKGEPGDDGPSGAEGPPG-P--QGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAP
960 970 980 990 1000 1010
300 310 320 330 340 350
pF1KE4 GEPGMPGKDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGEL
: : : : : ::: : :: ::.:.:: :: ::: :. : ::.::..: .
CCDS41 GASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGP------PGRDGAAGVKGDRGETGAV
1020 1030 1040 1050 1060
360 370 380 390 400 410
pF1KE4 GEAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQKGSMGDPGLP
: : : :: :: :: :..:. :. :. : .::.:: :: :..: :: .:. :. : :
CCDS41 GAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEP
1070 1080 1090 1100 1110 1120
420 430 440 450 460 470
pF1KE4 GPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPSGLVGPKGESGSRGELGPK
: .::.: : : : :: : .: :..: : .: :: : :::.:..:. : ::
CCDS41 GERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPI
1130 1140 1150 1160 1170 1180
480 490 500 510 520 530
pF1KE4 GTQGPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGKEASEQRIRELCGGMISEQI
: :: : :: : :::: : : :: :: ::.
CCDS41 GPPGPRGRSGETGPAGPPGNPGPPGPPGPPG----PGIDMSAFAGLGPREKGPDPLQYMR
1190 1200 1210 1220 1230 1240
540 550 560 570 580 590
pF1KE4 AQLAAHLRKPLAPGSIGRPGPAGPPGPPGPPGSIGHPGARGPPGYRGPTGELGDPGPRGN
CCDS41 ADQAAGGLRQHDAEVDATLKSLNNQIESIRSPEGSRKNPARTCRDLKLCHPEWKSGDYWI
1250 1260 1270 1280 1290 1300
>>CCDS75932.1 COL5A1 gene_id:1289|Hs108|chr9 (1838 aa)
initn: 1227 init1: 1227 opt: 1838 Z-score: 723.5 bits: 145.7 E(32554): 5.6e-34
Smith-Waterman score: 1974; 46.0% identity (57.2% similar) in 689 aa overlap (29-659:919-1577)
10 20 30 40 50
pF1KE4 MAGPRACAPLLLLLLLGELLAAAGAQRVGLPGPPGPPGPPGKPGQDGIDGEAGPPGLP
: :: : : :: :..: :: :::::
CCDS75 GFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGER
890 900 910 920 930 940
60 70 80 90 100
pF1KE4 GP---------PGPKGAPGKPGKPGEAGLPGLPGVDGLTGRDGPPGPKGAPGERGSLGPP
:: ::::: :: ::: : : :: : :. :. ::::: :. : .: :
CCDS75 GPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGET
950 960 970 980 990 1000
110 120 130 140 150 160
pF1KE4 GPPGLGGK-GLPGPPGEAGVSGPPGGIGLRGPPGPSGLPGLPGPPGPPGPPGHPGVL-PE
:: : :. : :::::: :. : : : .: :::.:::: :::: : :: :. :
CCDS75 GPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPV
1010 1020 1030 1040 1050 1060
170 180 190 200 210 220
pF1KE4 GATDLQCPSICPPGPPGPPGMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGL
:: :. . ::::::: : :: .::.: : : :. : .: ::: : : :: :
CCDS75 GALGLK-GNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGP
1070 1080 1090 1100 1110 1120
230 240 250 260 270 280
pF1KE4 QGPRGLRGLPGPLGPPGDRGPIGF------RGPPGIPGAPGKAGDRGERGPEGFRGPKGD
::: : :: ::.: :: ::.: .: : :: :. ::.::.:: : ::.:
CCDS75 QGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGP
1130 1140 1150 1160 1170 1180
290 300 310 320
pF1KE4 LGRPGPKGTPGVAGPSGE---------------PGMPGKDGQNGVPGLDGQKGEAGR---
.:.:::.:. : :: :. :: :: : .:.:: :.:::.:
CCDS75 IGQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQ
1190 1200 1210 1220 1230 1240
330 340 350 360 370
pF1KE4 ---NGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGELGEAGPSGEPGVPGDAGMPG---E
: :: .::.: :: : : : :. : .:: :: : .::::.::..: :: :
CCDS75 MGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGE
1250 1260 1270 1280 1290 1300
380 390 400 410 420 430
pF1KE4 RGEAGHRGSAGALGPQGPPGAPGVRGFQGQKGSMGDPGLPGPQGLRGDVGDRGPGGAAGP
::: :. : .:: :: :: : :: : .:. : .: :: ::: : : .:. :: :
CCDS75 RGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGP---PGD
1310 1320 1330 1340 1350 1360
440 450 460 470 480 490
pF1KE4 KGDQGIAGSDGLPGDKGELGPSGLVGPKGESGSRGELGPKGTQGPNGTSGVQGVPGPPG-
:::.: :. : :: :: :::: : :. : : ::.: :: .:..: :. ::::
CCDS75 KGDDGEPGQTGSPGPTGEPGPSG---PPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGK
1370 1380 1390 1400 1410 1420
500 510 520 530 540 550
pF1KE4 --PLGLQGVPGVPGITGKPGVPGKEASEQRIRELCGGMISEQIAQLAAHLRKPLAPGSIG
:.: ::.:: :: : :.:: ..:: :. : .:: :
CCDS75 TGPIGPQGAPGKPGPDGLRGIPGP-VGEQ-------GL--------------PGSPGPDG
1430 1440 1450
560 570 580 590 600
pF1KE4 RPGPAGPPGPPG------PPGSIGHPGARG---PPGYRGPTGELGDPGPRGNQGDRGDKG
::: :::: :: : : :::: : ::: .: :. : :::.:..: .:..:
CCDS75 PPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSSGPKGEQG
1460 1470 1480 1490 1500 1510
610 620 630 640 650 660
pF1KE4 AAGA----GLDGPEGDQGPQGPQGVPGTS-KDGQDGAPGEPGPPGDPGLPGAIGAQGTPG
.: : :: : :: ::.:. :.: : : :.::::: :: :: . : :
CCDS75 ITGPSGPIGPPGPPGLPGPPGPKGAKGSSGPTGPKGEAGHPGPPGPPGPPGEV-IQPLPI
1520 1530 1540 1550 1560 1570
670 680
pF1KE4 ICDTSACQGAVLGGVGEKSGSRSS
CCDS75 QASRTRRNIDASQLLDDGNGENYVDYADGMEEIFGSLNSLKLEIEQMKRPLGTQQNPART
1580 1590 1600 1610 1620 1630
>--
initn: 2000 init1: 1027 opt: 1292 Z-score: 515.4 bits: 107.2 E(32554): 2.2e-22
Smith-Waterman score: 1360; 45.3% identity (55.9% similar) in 488 aa overlap (29-505:444-916)
10 20 30 40 50
pF1KE4 MAGPRACAPLLLLLLLGELLAAAGAQRVGLPGPPGPPGPPGKP-----GQ--DGIDGE
:. :: : : :.: :. .: :
CCDS75 ENYYDPYYDPTSSPSEIGPGMPANQDTIYEGIGGPRGEKGQKGEPAIIEPGMLIEGPPGP
420 430 440 450 460 470
60 70 80 90 100 110
pF1KE4 AGPPGLPGPPGPKGAPGKPGKPGEAGLPGLPGVDGLTGRDGPPGPKGAPGERGSLGPPGP
:: ::::::: : :. : ::: : :: ::. : : :::: : .: :
CCDS75 EGPAGLPGPPGTMGPTGQVGDPGERGPPGRPGLPGADGLPGPPGTMLMLPFR--FGGGGD
480 490 500 510 520 530
120 130 140 150 160
pF1KE4 PGLGGKGLPGPPGEAGVSGPPGGIGLRGPPGPSGLPGLPGPPGPPGP---PGHPG-VLPE
: : . . ..: . . ..:::: :: :: : ::: :::: :.:: : :.
CCDS75 AGSKGPMVSAQESQAQAILQQARLALRGPAGPMGLTGRPGPVGPPGSGGLKGEPGDVGPQ
540 550 560 570 580 590
170 180 190 200 210 220
pF1KE4 GATDLQCPSICPPGPPGPPGMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGL
: .: ::::: : :: .: .: : .: :. : ::: : : ::::: :
CCDS75 GPRGVQ-------GPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGH
600 610 620 630 640
230 240 250 260 270 280
pF1KE4 QGPRGLRGLPGPLGPPGDRGPIGFRGPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGP
.: : : ::: : :.:: : :: :.:: :: : : .:: : :: : : :
CCDS75 RGDPGPSGPPGPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVTGMDGQ
650 660 670 680 690 700
290 300 310 320 330 340
pF1KE4 KGTPGVAGPSGEPGMPGKDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGE
: : .::.:::: : ::.: :: .: : : : :::::: : ::::: :. :
CCDS75 PGPKGNVGPQGEPGPP---GQQGNPGAQGLPGPQGAIGPPGEKGPLGKPGLPGMPGADGP
710 720 730 740 750 760
350 360 370 380 390 400
pF1KE4 KGERGRAGELGEAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQ
:. :. : :: : .: :: : :.:: :: : : : : .: : : ::.:.
CCDS75 PGHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKGD
770 780 790 800 810 820
410 420 430 440 450 460
pF1KE4 KGSMGDPGLPGPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPSGLVGPKGE
: :: : :: : ::. : .:: : .::.:: : : ::.::.:: :: : :.
CCDS75 MGIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGDPGPLGP---PGEKGKLGVPGLPGYPGR
830 840 850 860 870
470 480 490 500 510 520
pF1KE4 SGSRGELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGKEASEQRIRE
.: .: .: : : :: .: .:.:: ::: : .: :
CCDS75 QGPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGG
880 890 900 910 920 930
530 540 550 560 570 580
pF1KE4 LCGGMISEQIAQLAAHLRKPLAPGSIGRPGPAGPPGPPGPPGSIGHPGARGPPGYRGPTG
CCDS75 DGPAGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGV
940 950 960 970 980 990
>>CCDS6982.1 COL5A1 gene_id:1289|Hs108|chr9 (1838 aa)
initn: 1227 init1: 1227 opt: 1838 Z-score: 723.5 bits: 145.7 E(32554): 5.6e-34
Smith-Waterman score: 1974; 46.0% identity (57.2% similar) in 689 aa overlap (29-659:919-1577)
10 20 30 40 50
pF1KE4 MAGPRACAPLLLLLLLGELLAAAGAQRVGLPGPPGPPGPPGKPGQDGIDGEAGPPGLP
: :: : : :: :..: :: :::::
CCDS69 GFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGER
890 900 910 920 930 940
60 70 80 90 100
pF1KE4 GP---------PGPKGAPGKPGKPGEAGLPGLPGVDGLTGRDGPPGPKGAPGERGSLGPP
:: ::::: :: ::: : : :: : :. :. ::::: :. : .: :
CCDS69 GPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGET
950 960 970 980 990 1000
110 120 130 140 150 160
pF1KE4 GPPGLGGK-GLPGPPGEAGVSGPPGGIGLRGPPGPSGLPGLPGPPGPPGPPGHPGVL-PE
:: : :. : :::::: :. : : : .: :::.:::: :::: : :: :. :
CCDS69 GPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPV
1010 1020 1030 1040 1050 1060
170 180 190 200 210 220
pF1KE4 GATDLQCPSICPPGPPGPPGMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGL
:: :. . ::::::: : :: .::.: : : :. : .: ::: : : :: :
CCDS69 GALGLK-GNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGP
1070 1080 1090 1100 1110 1120
230 240 250 260 270 280
pF1KE4 QGPRGLRGLPGPLGPPGDRGPIGF------RGPPGIPGAPGKAGDRGERGPEGFRGPKGD
::: : :: ::.: :: ::.: .: : :: :. ::.::.:: : ::.:
CCDS69 QGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGP
1130 1140 1150 1160 1170 1180
290 300 310 320
pF1KE4 LGRPGPKGTPGVAGPSGE---------------PGMPGKDGQNGVPGLDGQKGEAGR---
.:.:::.:. : :: :. :: :: : .:.:: :.:::.:
CCDS69 IGQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQ
1190 1200 1210 1220 1230 1240
330 340 350 360 370
pF1KE4 ---NGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGELGEAGPSGEPGVPGDAGMPG---E
: :: .::.: :: : : : :. : .:: :: : .::::.::..: :: :
CCDS69 MGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGE
1250 1260 1270 1280 1290 1300
380 390 400 410 420 430
pF1KE4 RGEAGHRGSAGALGPQGPPGAPGVRGFQGQKGSMGDPGLPGPQGLRGDVGDRGPGGAAGP
::: :. : .:: :: :: : :: : .:. : .: :: ::: : : .:. :: :
CCDS69 RGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGP---PGD
1310 1320 1330 1340 1350 1360
440 450 460 470 480 490
pF1KE4 KGDQGIAGSDGLPGDKGELGPSGLVGPKGESGSRGELGPKGTQGPNGTSGVQGVPGPPG-
:::.: :. : :: :: :::: : :. : : ::.: :: .:..: :. ::::
CCDS69 KGDDGEPGQTGSPGPTGEPGPSG---PPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGK
1370 1380 1390 1400 1410 1420
500 510 520 530 540 550
pF1KE4 --PLGLQGVPGVPGITGKPGVPGKEASEQRIRELCGGMISEQIAQLAAHLRKPLAPGSIG
:.: ::.:: :: : :.:: ..:: :. : .:: :
CCDS69 TGPIGPQGAPGKPGPDGLRGIPGP-VGEQ-------GL--------------PGSPGPDG
1430 1440 1450
560 570 580 590 600
pF1KE4 RPGPAGPPGPPG------PPGSIGHPGARG---PPGYRGPTGELGDPGPRGNQGDRGDKG
::: :::: :: : : :::: : ::: .: :. : :::.:..: .:..:
CCDS69 PPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSSGPKGEQG
1460 1470 1480 1490 1500 1510
610 620 630 640 650 660
pF1KE4 AAGA----GLDGPEGDQGPQGPQGVPGTS-KDGQDGAPGEPGPPGDPGLPGAIGAQGTPG
.: : :: : :: ::.:. :.: : : :.::::: :: :: . : :
CCDS69 ITGPSGPIGPPGPPGLPGPPGPKGAKGSSGPTGPKGEAGHPGPPGPPGPPGEV-IQPLPI
1520 1530 1540 1550 1560 1570
670 680
pF1KE4 ICDTSACQGAVLGGVGEKSGSRSS
CCDS69 QASRTRRNIDASQLLDDGNGENYVDYADGMEEIFGSLNSLKLEIEQMKRPLGTQQNPART
1580 1590 1600 1610 1620 1630
>--
initn: 2000 init1: 1027 opt: 1292 Z-score: 515.4 bits: 107.2 E(32554): 2.2e-22
Smith-Waterman score: 1360; 45.3% identity (55.9% similar) in 488 aa overlap (29-505:444-916)
10 20 30 40 50
pF1KE4 MAGPRACAPLLLLLLLGELLAAAGAQRVGLPGPPGPPGPPGKP-----GQ--DGIDGE
:. :: : : :.: :. .: :
CCDS69 ENYYDPYYDPTSSPSEIGPGMPANQDTIYEGIGGPRGEKGQKGEPAIIEPGMLIEGPPGP
420 430 440 450 460 470
60 70 80 90 100 110
pF1KE4 AGPPGLPGPPGPKGAPGKPGKPGEAGLPGLPGVDGLTGRDGPPGPKGAPGERGSLGPPGP
:: ::::::: : :. : ::: : :: ::. : : :::: : .: :
CCDS69 EGPAGLPGPPGTMGPTGQVGDPGERGPPGRPGLPGADGLPGPPGTMLMLPFR--FGGGGD
480 490 500 510 520 530
120 130 140 150 160
pF1KE4 PGLGGKGLPGPPGEAGVSGPPGGIGLRGPPGPSGLPGLPGPPGPPGP---PGHPG-VLPE
: : . . ..: . . ..:::: :: :: : ::: :::: :.:: : :.
CCDS69 AGSKGPMVSAQESQAQAILQQARLALRGPAGPMGLTGRPGPVGPPGSGGLKGEPGDVGPQ
540 550 560 570 580 590
170 180 190 200 210 220
pF1KE4 GATDLQCPSICPPGPPGPPGMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGL
: .: ::::: : :: .: .: : .: :. : ::: : : ::::: :
CCDS69 GPRGVQ-------GPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGH
600 610 620 630 640
230 240 250 260 270 280
pF1KE4 QGPRGLRGLPGPLGPPGDRGPIGFRGPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGP
.: : : ::: : :.:: : :: :.:: :: : : .:: : :: : : :
CCDS69 RGDPGPSGPPGPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVTGMDGQ
650 660 670 680 690 700
290 300 310 320 330 340
pF1KE4 KGTPGVAGPSGEPGMPGKDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGE
: : .::.:::: : ::.: :: .: : : : :::::: : ::::: :. :
CCDS69 PGPKGNVGPQGEPGPP---GQQGNPGAQGLPGPQGAIGPPGEKGPLGKPGLPGMPGADGP
710 720 730 740 750 760
350 360 370 380 390 400
pF1KE4 KGERGRAGELGEAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQ
:. :. : :: : .: :: : :.:: :: : : : : .: : : ::.:.
CCDS69 PGHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKGD
770 780 790 800 810 820
410 420 430 440 450 460
pF1KE4 KGSMGDPGLPGPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPSGLVGPKGE
: :: : :: : ::. : .:: : .::.:: : : ::.::.:: :: : :.
CCDS69 MGIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGDPGPLGP---PGEKGKLGVPGLPGYPGR
830 840 850 860 870
470 480 490 500 510 520
pF1KE4 SGSRGELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGKEASEQRIRE
.: .: .: : : :: .: .:.:: ::: : .: :
CCDS69 QGPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGG
880 890 900 910 920 930
530 540 550 560 570 580
pF1KE4 LCGGMISEQIAQLAAHLRKPLAPGSIGRPGPAGPPGPPGPPGSIGHPGARGPPGYRGPTG
CCDS69 DGPAGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGV
940 950 960 970 980 990
>>CCDS33350.1 COL5A2 gene_id:1290|Hs108|chr2 (1499 aa)
initn: 1210 init1: 1210 opt: 1833 Z-score: 722.5 bits: 145.2 E(32554): 6.3e-34
Smith-Waterman score: 1873; 46.6% identity (57.6% similar) in 672 aa overlap (24-669:205-852)
10 20 30 40
pF1KE4 MAGPRACAPLLLLLLLGELLAAAGAQRVGL-PG---PPGPPGPPGKPGQDGID
:.: ::: :: : :: :: : ::.:
CCDS33 PPGHPSHPGPDGLSRPFSAQMAGLDEKSGLGSQ-VGLMPGSVGPVGPRGPQGLQGQQGGA
180 190 200 210 220 230
50 60 70 80 90 100
pF1KE4 GEAGPPGLPGPPGPKGAPGKPGKPGEAGLPGLPGVDGLTGRDGPPGP---KGAPGERGSL
: .:::: :: ::: : :. : : :: :: :: ::.: :: :.:: ::
CCDS33 GPTGPPGEPGDPGPMGPIGSRGPEGP---PGKPGEDGEPGRNGNPGEVGFAGSPGARGFP
240 250 260 270 280 290
110 120 130 140 150
pF1KE4 GPPGPPGLGG----KGLPGPPGEAGV------SGPPGGIGLRGPPGPSGLPGLPGPPGPP
: :: ::: : ::: :: ::.:. .:: : .: :: :: :.:: : ::
CCDS33 GAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPRGMPGERGRLGPQ
300 310 320 330 340 350
160 170 180 190 200 210
pF1KE4 GPPGHPGV--LPEGATDLQCPSICP--PGPPGPPGMPGFKGPTGYKGEQGEVGKDGEKGD
: ::. :. .: : . : : : :: ::: : :::: .: .: :. :: :
CCDS33 GAPGQRGAHGMP-GKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGETGP
360 370 380 390 400
220 230 240 250 260 270
pF1KE4 PGPPGPAGLPGSVGLQGPRGLRGLPGPLGPPGDRGPIGFRGPPGIPGAPGKAGDRGERGP
::: : ::::..: .: : .: : : :: :: : :::: :: :..: .: ::
CCDS33 PGPVGSPGLPGAIGTDGTPGAKG---PTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQ
410 420 430 440 450 460
280 290 300 310 320
pF1KE4 EGFRGPKGDLGRPGPKGTPG---VAGPSGEPGMPGKDGQNGVPGLDGQKGEAGRNGAPGE
: : : :. :::: :: . :: : :: :: : : :: : : .:. ::::.
CCDS33 PGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGN
470 480 490 500 510 520
330 340 350 360 370 380
pF1KE4 KGPNGLPGLPGRAGSKGEKGERGRAGELGEAGPSGEPGVPGDAGMPGERGEAGHRGSAGA
.: : :::: :: .:::: .: : : .:.:: ::. :.:: :: .:. : :
CCDS33 RGFPGSDGLPG---PKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGP
530 540 550 560 570 580
390 400 410 420 430 440
pF1KE4 LGPQGPPGAPGVRGFQGQKGSMGDPGLPGPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGL
: :: :::: : : ::.: : :: .:: : :. : : : :. :. :. :
CCDS33 EGKLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGA
590 600 610 620 630 640
450 460 470 480 490 500
pF1KE4 PGDKGELGPSGLVGPKGESGSRGELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPGI
:: ::.:::: ::: : .: ::: ::: : .: ::.:::::: : : :: :.
CCDS33 PGKDGEVGPSGPVGPPGLAGERGE------QGPPGPTGFQGLPGPPGPPGEGGKPGDQGV
650 660 670 680 690
510 520 530 540 550 560
pF1KE4 TGKPGVPGKEASEQRIRELCGGMISEQIAQLAAHLRKPLAPGSIGRPGPAGPPGPPGPPG
: ::. : . . . : : :. : . .: .: : : :: : ::: : ::
CCDS33 PGDPGAVGPLGPRGE-RGNPGERGEPGITGLPG--EKGMAGGH-GPDGPKGSPGPSGTPG
700 710 720 730 740 750
570 580 590 600 610 620
pF1KE4 SIGHPGARGPPGYRGPTGELGDPGPRGNQGDRGDKGAAG-AGLDGPEGDQGPQGPQGVPG
. : :: .: :: :: .: :::.:..: :.::: : :: :: .: :: :: : :
CCDS33 DTGPPGLQGMPGERGIAGT---PGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAG
760 770 780 790 800 810
630 640 650 660 670 680
pF1KE4 -TSKDGQDGAPGEPGPPGDPGLPGAIGAQGTPGICDTSACQGAVLGGVGEKSGSRSS
:.. :. : : ::::. : ::. : .: : .. ::
CCDS33 PTGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKG
820 830 840 850 860 870
CCDS33 DAGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAG
880 890 900 910 920 930
>--
initn: 1089 init1: 1089 opt: 1128 Z-score: 453.8 bits: 95.5 E(32554): 5.9e-19
Smith-Waterman score: 1208; 40.3% identity (51.0% similar) in 553 aa overlap (91-632:854-1297)
70 80 90 100 110
pF1KE4 PGPKGAPGKPGKPGEAGLPGLPGVDGLTGRDGPPGPKGAPGE---RGSLGPPGPPGLGGK
:: :: :: ::: .:. : ::: ::.:.
CCDS33 VGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGS
830 840 850 860 870 880
120 130 140 150 160 170
pF1KE4 GLPGPPGEAGVSGPPGGIGLRGPPGPSGLPGLPGPPGPPGPPGHPGVLPEGATDLQCPSI
::: : :: : :: : .:::: .:.:: : ::::: :
CCDS33 --PGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAG-----------------
890 900 910 920
180 190 200 210 220 230
pF1KE4 CPPGPPGPPGMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGLP
::: :: : :: .:: : .:. : . :. :: :: :: : ::. .: : : :
CCDS33 -APGPAGPLGEPGKEGPPGLRGDPG---SHGRVGDRGPAGPPGGPGD---KGDPGEDGQP
930 940 950 960 970
240 250 260 270 280 290
pF1KE4 GPLGPPGDRGPIGFRGPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAGPS
:: ::: :: : : :: : ::. ::::: :. ::: :::: .::.
CCDS33 GPDGPP---GPAGTTGQRGIVGMPGQ---RGERGMPGL---------PGPAGTPGKVGPT
980 990 1000 1010 1020
300 310 320 330 340 350
pF1KE4 GEPGMPGKDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGEL
: : : : : :: .: :: :: .:: : : ::: :. ::.:.:: :
CCDS33 GATGDKGPPGPVGPPGSNGPVGE------PGPEGPAGNDGTPGRDGAVGERGDRGDPGPA
1030 1040 1050 1060 1070
360 370 380 390 400 410
pF1KE4 GEAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQKGSMGDPGLP
: : .: ::.:: .: ::. ::.::. :. :: :::: : :: ::
CCDS33 GLPGSQGAPGTPGPVGAPGD---AGQRGDPGSRGPIGPPGRAGKRG------------LP
1080 1090 1100 1110 1120
420 430 440 450 460 470
pF1KE4 GPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPSGLVGPKGESGSRGELGPK
:::: ::: ::.: : : :: .:..: .:::: : : : .: .: : .::.
CCDS33 GPQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLPG------PPGPNGEQGSAGIPGPFGPR
1130 1140 1150 1160 1170
480 490 500 510 520 530
pF1KE4 GTQGPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGKEASEQRIRELCGGMISEQI
: :: : :: .: ::: ::.: : ::. :. : : :
CCDS33 GPPGPVGPSGKEGNPGPLGPIG----P--PGVRGSVGEAGPE------------------
1180 1190 1200 1210
540 550 560 570 580
pF1KE4 AQLAAHLRKPLAPGSIGRPGPAGPPGPPGPPGSI--------GHPGARGPPGYRGPTGEL
: :: :::::::::: . :: : : .
CCDS33 ----------------GPPGEPGPPGPPGPPGHLTAALGDIMGHYDESMPDPLPEFTEDQ
1220 1230 1240 1250
590 600 610 620 630 640
pF1KE4 GDPGPRGNQGDRGDKGAAGAGLDGPEGDQGPQGPQGVPGTSKDGQDGAPGEPGPPGDPGL
. : . :. : : ... . . : ..:.: . :. . :
CCDS33 AAPDDK-NKTDPGVHATLKSLSSQIETMRSPDGSKKHPARTCDDLKLCHSAKQSGEYWID
1260 1270 1280 1290 1300 1310
650 660 670 680
pF1KE4 PGAIGAQGTPGICDTSACQGAVLGGVGEKSGSRSS
CCDS33 PNQGSVEDAIKVYCNMETGETCISANPSSVPRKTWWASKSPDNKPVWYGLDMNRGSQFAY
1320 1330 1340 1350 1360 1370
684 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 23:56:22 2016 done: Sat Nov 5 23:56:23 2016
Total Scan time: 4.870 Total Display time: 0.320
Function used was FASTA [36.3.4 Apr, 2011]