Result of FASTA (ccds) for
pFN21AE4546
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE4546, 640 aa
1>>>pF1KE4546 640 - 640 aa - 640 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.6207+/-0.000936; mu= 18.4055+/- 0.057
mean_var=75.5856+/-15.084, 0's: 0 Z-trim(105.7): 40 B-trim: 0 in 0/52
Lambda= 0.147521
statistics sampled from 8564 (8594) to 8564 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.633), E-opt: 0.2 (0.264), width: 16
Scan time: 2.980
The best scores are: opt bits E(32554)
CCDS4942.1 EFHC1 gene_id:114327|Hs108|chr6 ( 640) 4298 924.5 0
CCDS55021.1 EFHC1 gene_id:114327|Hs108|chr6 ( 621) 4153 893.6 0
CCDS55405.1 EFHC2 gene_id:80258|Hs108|chrX ( 749) 701 159.0 2.2e-38
>>CCDS4942.1 EFHC1 gene_id:114327|Hs108|chr6 (640 aa)
initn: 4298 init1: 4298 opt: 4298 Z-score: 4941.1 bits: 924.5 E(32554): 0
Smith-Waterman score: 4298; 99.7% identity (99.8% similar) in 640 aa overlap (1-640:1-640)
10 20 30 40 50 60
pF1KE4 MVSNPVHGLPFLPGTSFKDSTKTAFHRSQTLSYRNGYAIVRRPTVGIGGDRLQFNQLSQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS49 MVSNPVHGLPFLPGTSFKDSTKTAFHRSQTLSYRNGYAIVRRPTVGIGGDRLQFNQLSQA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 ELDELASKAPVLTYGQPKQAPPADFIPAHVAFDKKVLKFDAYFQEDVPMSTEEQYRIRQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS49 ELDELASKAPVLTYGQPKQAPPADFIPAHVAFDKKVLKFDAYFQEDVPMSTEEQYRIRQV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 NIYYYLEDDSMSVIEPVVENSGILQGKLIKRQRLAKNDRGDHYHWKDLNRGINITIYGKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS49 NIYYYLEDDSMSVIEPVVENSGILQGKLIKRQRLAKNDRGDHYHWKDLNRGINITIYGKT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 FRVVDCDQFTQVFLESQGIELNPPEKMALDPYTELRKQPLRKYVTPSDFDQLKQFLTFDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS49 FRVVDCDQFTQVFLESQGIELNPPEKMALDPYTELRKQPLRKYVTPSDFDQLKQFLTFDK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 QVLRFYAIWDDTDSMYGECRTYIIHYYLMDDTVEIREVHERNDGIDPFPLLMNRQRVPKV
:::::::::::::::::::::::::::::::::::::::::::: :::::::::::::::
CCDS49 QVLRFYAIWDDTDSMYGECRTYIIHYYLMDDTVEIREVHERNDGRDPFPLLMNRQRVPKV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 LVENAKNFPQCVLEISDQEVLEWYTAKDFIVGKSLTILGRTFFIYDCDPFTRRYYKEKFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS49 LVENAKNFPQCVLEISDQEVLEWYTAKDFIVGKSLTILGRTFFIYDCDPFTRRYYKEKFG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 ITDLPRIDVSKREPPPVKQELPPYNGFGLVEDSAQNCFALIPKAPKKDVIKMLVNDNKVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS49 ITDLPRIDVSKREPPPVKQELPPYNGFGLVEDSAQNCFALIPKAPKKDVIKMLVNDNKVL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE4 RYLAVLESPIPEDKDRRFVFSYFLATDMISIFEPPVRNSGIIGGKYLGRTKVVKPYSTVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS49 RYLAVLESPIPEDKDRRFVFSYFLATDMISIFEPPVRNSGIIGGKYLGRTKVVKPYSTVD
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE4 NPVYYGPSDFFIGAVIEVFGHRFIILDTDEYVLKYMESNAAQYSPEALASIQNHVRKREA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS49 NPVYYGPSDFFIGAVIEVFGHRFIILDTDEYVLKYMESNAAQYSPEALASIQNHVRKREA
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE4 PAPEAESKQTEKDPGVQELEALIDTIQKQLKDHSCKDNIREAFQIYDKEASGYVDRDMFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS49 PAPEAESKQTEKDPGVQELEALIDTIQKQLKDHSCKDNIREAFQIYDKEASGYVDRDMFF
550 560 570 580 590 600
610 620 630 640
pF1KE4 KICESLNVPVDDSLVKELLRMCSHGEGKINYYNFVRAFSN
::::::::::::::::::.:::::::::::::::::::::
CCDS49 KICESLNVPVDDSLVKELIRMCSHGEGKINYYNFVRAFSN
610 620 630 640
>>CCDS55021.1 EFHC1 gene_id:114327|Hs108|chr6 (621 aa)
initn: 4153 init1: 4153 opt: 4153 Z-score: 4774.5 bits: 893.6 E(32554): 0
Smith-Waterman score: 4153; 99.7% identity (99.8% similar) in 619 aa overlap (22-640:3-621)
10 20 30 40 50 60
pF1KE4 MVSNPVHGLPFLPGTSFKDSTKTAFHRSQTLSYRNGYAIVRRPTVGIGGDRLQFNQLSQA
:::::::::::::::::::::::::::::::::::::::
CCDS55 MLKTAFHRSQTLSYRNGYAIVRRPTVGIGGDRLQFNQLSQA
10 20 30 40
70 80 90 100 110 120
pF1KE4 ELDELASKAPVLTYGQPKQAPPADFIPAHVAFDKKVLKFDAYFQEDVPMSTEEQYRIRQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 ELDELASKAPVLTYGQPKQAPPADFIPAHVAFDKKVLKFDAYFQEDVPMSTEEQYRIRQV
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE4 NIYYYLEDDSMSVIEPVVENSGILQGKLIKRQRLAKNDRGDHYHWKDLNRGINITIYGKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 NIYYYLEDDSMSVIEPVVENSGILQGKLIKRQRLAKNDRGDHYHWKDLNRGINITIYGKT
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE4 FRVVDCDQFTQVFLESQGIELNPPEKMALDPYTELRKQPLRKYVTPSDFDQLKQFLTFDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 FRVVDCDQFTQVFLESQGIELNPPEKMALDPYTELRKQPLRKYVTPSDFDQLKQFLTFDK
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE4 QVLRFYAIWDDTDSMYGECRTYIIHYYLMDDTVEIREVHERNDGIDPFPLLMNRQRVPKV
:::::::::::::::::::::::::::::::::::::::::::: :::::::::::::::
CCDS55 QVLRFYAIWDDTDSMYGECRTYIIHYYLMDDTVEIREVHERNDGRDPFPLLMNRQRVPKV
230 240 250 260 270 280
310 320 330 340 350 360
pF1KE4 LVENAKNFPQCVLEISDQEVLEWYTAKDFIVGKSLTILGRTFFIYDCDPFTRRYYKEKFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 LVENAKNFPQCVLEISDQEVLEWYTAKDFIVGKSLTILGRTFFIYDCDPFTRRYYKEKFG
290 300 310 320 330 340
370 380 390 400 410 420
pF1KE4 ITDLPRIDVSKREPPPVKQELPPYNGFGLVEDSAQNCFALIPKAPKKDVIKMLVNDNKVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 ITDLPRIDVSKREPPPVKQELPPYNGFGLVEDSAQNCFALIPKAPKKDVIKMLVNDNKVL
350 360 370 380 390 400
430 440 450 460 470 480
pF1KE4 RYLAVLESPIPEDKDRRFVFSYFLATDMISIFEPPVRNSGIIGGKYLGRTKVVKPYSTVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 RYLAVLESPIPEDKDRRFVFSYFLATDMISIFEPPVRNSGIIGGKYLGRTKVVKPYSTVD
410 420 430 440 450 460
490 500 510 520 530 540
pF1KE4 NPVYYGPSDFFIGAVIEVFGHRFIILDTDEYVLKYMESNAAQYSPEALASIQNHVRKREA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 NPVYYGPSDFFIGAVIEVFGHRFIILDTDEYVLKYMESNAAQYSPEALASIQNHVRKREA
470 480 490 500 510 520
550 560 570 580 590 600
pF1KE4 PAPEAESKQTEKDPGVQELEALIDTIQKQLKDHSCKDNIREAFQIYDKEASGYVDRDMFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 PAPEAESKQTEKDPGVQELEALIDTIQKQLKDHSCKDNIREAFQIYDKEASGYVDRDMFF
530 540 550 560 570 580
610 620 630 640
pF1KE4 KICESLNVPVDDSLVKELLRMCSHGEGKINYYNFVRAFSN
::::::::::::::::::.:::::::::::::::::::::
CCDS55 KICESLNVPVDDSLVKELIRMCSHGEGKINYYNFVRAFSN
590 600 610 620
>>CCDS55405.1 EFHC2 gene_id:80258|Hs108|chrX (749 aa)
initn: 954 init1: 240 opt: 701 Z-score: 802.7 bits: 159.0 E(32554): 2.2e-38
Smith-Waterman score: 1195; 36.6% identity (63.6% similar) in 580 aa overlap (9-544:3-562)
10 20 30 40 50
pF1KE4 MVSNPVHGLPFLPGTSF-KDSTKTAFHRSQTLSYRNG-YAIVRRPTVGIGGDRLQFNQLS
::.:::.:: .. : ::.:: .. :. . .: ::::. : :.
CCDS55 MALPLLPGNSFNRNVGKEKFHKSQHWGFCNNVMMLVSDEKPGIGGEPL----LG
10 20 30 40 50
60 70 80 90 100 110
pF1KE4 QAELDELASKAPVLTYGQPKQAPPADFIPAHVAFDKKVLKFDAYFQEDVPMSTEEQYRIR
: .. : . :. .. .:. :::::.::.::::..:.: ... .::::
CCDS55 Q----KIKPKCSIYPKGDGSD------VPSWVAFDKQVLSFDAYLEEEVLDKSQTNYRIR
60 70 80 90 100
120 130 140 150 160 170
pF1KE4 QVNIYYYLEDDSMSVIEPVVENSGILQGKLIKRQR--LAKNDRGDHYHWKDLNRGINITI
.::.: :::...: :: :.:::.::: :.:.: : :. . : .: : ....
CCDS55 YYKIYFYPEDDTIQVNEPEVKNSGLLQGTSIRRHRITLPPPDEDQFYTVYHFNVGTEVVF
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE4 YGKTFRVVDCDQFTQVFLESQGIELNPPEKMALDPYTELRKQ------PLRKYVTPSDFD
::.::.. ::: ::. ::.. :...::: . ::: ..:.. ::: : . .:
CCDS55 YGRTFKIYDCDAFTRNFLRKIGVKVNPPVQCPEDPYMKIRREVVEHVEPLRPYES---LD
170 180 190 200 210
240 250 260 270 280 290
pF1KE4 QLKQFLTFDKQVLRFYAIWDDTDSMYGECRTYIIHYYLMDDTVEIREVHERNDGIDPFPL
::::: . ..: :. .:::. ::.:. : :.::.: :::.::.:. ...: : . .
CCDS55 TLKQFLQYHGKILCFFCLWDDSVSMFGDRRELILHYFLCDDTIEIKELLPHSSGRDALKM
220 230 240 250 260 270
300 310 320
pF1KE4 LMNRQRVPK----------------VL------VENAKN---FPQCVLEISDQEVLEWYT
.. :...:: :: ..: . : . : :: :.:
CCDS55 FLRRSKLPKNCPPRVYQPGQITDRAVLNSYGDFIKNQADGYLFDRYKLGKVDQ---EFYK
280 290 300 310 320 330
330 340 350 360 370 380
pF1KE4 AKDFIVGKSLTILGRTFFIYDCDPFTRRYYKEKFGITDLPRIDVSKREPPP-VKQELPPY
.:. .: .... :: ..:::: ::. ::: :.:: .. .. . ::: .....:::
CCDS55 DSDLSLGVTINVWGRKVLLYDCDEFTKSYYKSKYGIENFTSVSCKPPSPPPKIERKFPPY
340 350 360 370 380 390
390 400 410 420 430
pF1KE4 NGFGLVEDSAQNCFALIPKAPKKDVIKMLVNDN-----KVLRYLAVLESPIPEDKDRRFV
:::: ::: .::. : : ... :.. .:. ..::..: : . : :: ::
CCDS55 NGFGSEEDSLRNCIDLKPTPHRRNFKKFMEKDSYGSKSNILRFFAKLVTDKCVDLDRMFV
400 410 420 430 440 450
440 450 460 470 480 490
pF1KE4 FSYFLATDMISIFEPPVRNSGIIGGKYLGRTKVVKPYSTV---DNPVYYGPSDFFIGAVI
.::.:. : ::.::: ::::: :: .: :..: :: . : . : ...::...
CCDS55 ISYYLGDDTISVFEPIERNSGIAGGMFLKRSRVKKPGQEVFKSELSEYIKAEELYIGVTV
460 470 480 490 500 510
500 510 520 530 540 550
pF1KE4 EVFGHRFIILDTDEYVLKYMESNAAQYSPEALASIQNHVRKREAPAPEAESKQTEKDPGV
.: :. : .:..:::.:.:::.:. .: : ......:. . :
CCDS55 NVNGYLFRLLNADEYTLNYMEQNTDKYPFSNLKLALQKLKQEEGKSRELKQVFKAADSKH
520 530 540 550 560 570
560 570 580 590 600 610
pF1KE4 QELEALIDTIQKQLKDHSCKDNIREAFQIYDKEASGYVDRDMFFKICESLNVPVDDSLVK
CCDS55 TNMVDYNTFRDILMSLTVGNLAEQEFVTIARHYRVPEGTCSDMDFLIALAHEKFKKNMFE
580 590 600 610 620 630
640 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 00:04:27 2016 done: Sun Nov 6 00:04:28 2016
Total Scan time: 2.980 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]