Result of FASTA (omim) for
pFN21AE4541
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE4541, 623 aa
1>>>pF1KE4541 623 - 623 aa - 623 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.7914+/-0.000459; mu= 16.2307+/- 0.028
mean_var=70.1618+/-14.075, 0's: 0 Z-trim(110.0): 26 B-trim: 119 in 1/51
Lambda= 0.153117
statistics sampled from 18293 (18308) to 18293 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.573), E-opt: 0.2 (0.215), width: 16
Scan time: 10.060
The best scores are: opt bits E(85289)
NP_001055 (OMIM: 606781,617044) transketolase isof ( 623) 4092 913.7 0
NP_001128527 (OMIM: 606781,617044) transketolase i ( 623) 4092 913.7 0
XP_011532356 (OMIM: 606781,617044) PREDICTED: tran ( 631) 4066 908.0 0
NP_001244957 (OMIM: 606781,617044) transketolase i ( 631) 4066 908.0 0
XP_011532357 (OMIM: 606781,617044) PREDICTED: tran ( 457) 2976 667.2 3.6e-191
NP_001139406 (OMIM: 300044) transketolase-like pro ( 540) 2218 499.7 1.1e-140
NP_001139405 (OMIM: 300044) transketolase-like pro ( 590) 2218 499.8 1.1e-140
NP_036385 (OMIM: 300044) transketolase-like protei ( 596) 2218 499.8 1.1e-140
NP_001166939 (OMIM: 179060,614111) pyruvate dehydr ( 341) 173 47.9 6.8e-05
NP_001302465 (OMIM: 179060,614111) pyruvate dehydr ( 341) 147 42.2 0.0036
NP_000916 (OMIM: 179060,614111) pyruvate dehydroge ( 359) 147 42.2 0.0038
>>NP_001055 (OMIM: 606781,617044) transketolase isoform (623 aa)
initn: 4092 init1: 4092 opt: 4092 Z-score: 4883.4 bits: 913.7 E(85289): 0
Smith-Waterman score: 4092; 100.0% identity (100.0% similar) in 623 aa overlap (1-623:1-623)
10 20 30 40 50 60
pF1KE4 MESYHKPDQQKLQALKDTANRLRISSIQATTAAGSGHPTSCCSAAEIMAVLFFHTMRYKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MESYHKPDQQKLQALKDTANRLRISSIQATTAAGSGHPTSCCSAAEIMAVLFFHTMRYKS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 QDPRNPHNDRFVLSKGHAAPILYAVWAEAGFLAEAELLNLRKISSDLDGHPVPKQAFTDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QDPRNPHNDRFVLSKGHAAPILYAVWAEAGFLAEAELLNLRKISSDLDGHPVPKQAFTDV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 ATGSLGQGLGAACGMAYTGKYFDKASYRVYCLLGDGELSEGSVWEAMAFASIYKLDNLVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ATGSLGQGLGAACGMAYTGKYFDKASYRVYCLLGDGELSEGSVWEAMAFASIYKLDNLVA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 ILDINRLGQSDPAPLQHQMDIYQKRCEAFGWHAIIVDGHSVEELCKAFGQAKHQPTAIIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ILDINRLGQSDPAPLQHQMDIYQKRCEAFGWHAIIVDGHSVEELCKAFGQAKHQPTAIIA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 KTFKGRGITGVEDKESWHGKPLPKNMAEQIIQEIYSQIQSKKKILATPPQEDAPSVDIAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KTFKGRGITGVEDKESWHGKPLPKNMAEQIIQEIYSQIQSKKKILATPPQEDAPSVDIAN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 IRMPSLPSYKVGDKIATRKAYGQALAKLGHASDRIIALDGDTKNSTFSEIFKKEHPDRFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IRMPSLPSYKVGDKIATRKAYGQALAKLGHASDRIIALDGDTKNSTFSEIFKKEHPDRFI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 ECYIAEQNMVSIAVGCATRNRTVPFCSTFAAFFTRAFDQIRMAAISESNINLCGSHCGVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ECYIAEQNMVSIAVGCATRNRTVPFCSTFAAFFTRAFDQIRMAAISESNINLCGSHCGVS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE4 IGEDGPSQMALEDLAMFRSVPTSTVFYPSDGVATEKAVELAANTKGICFIRTSRPENAII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IGEDGPSQMALEDLAMFRSVPTSTVFYPSDGVATEKAVELAANTKGICFIRTSRPENAII
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE4 YNNNEDFQVGQAKVVLKSKDDQVTVIGAGVTLHEALAAAELLKKEKINIRVLDPFTIKPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YNNNEDFQVGQAKVVLKSKDDQVTVIGAGVTLHEALAAAELLKKEKINIRVLDPFTIKPL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE4 DRKLILDSARATKGRILTVEDHYYEGGIGEAVSSAVVGEPGITVTHLAVNRVPRSGKPAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DRKLILDSARATKGRILTVEDHYYEGGIGEAVSSAVVGEPGITVTHLAVNRVPRSGKPAE
550 560 570 580 590 600
610 620
pF1KE4 LLKMFGIDRDAIAQAVRGLITKA
:::::::::::::::::::::::
NP_001 LLKMFGIDRDAIAQAVRGLITKA
610 620
>>NP_001128527 (OMIM: 606781,617044) transketolase isofo (623 aa)
initn: 4092 init1: 4092 opt: 4092 Z-score: 4883.4 bits: 913.7 E(85289): 0
Smith-Waterman score: 4092; 100.0% identity (100.0% similar) in 623 aa overlap (1-623:1-623)
10 20 30 40 50 60
pF1KE4 MESYHKPDQQKLQALKDTANRLRISSIQATTAAGSGHPTSCCSAAEIMAVLFFHTMRYKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MESYHKPDQQKLQALKDTANRLRISSIQATTAAGSGHPTSCCSAAEIMAVLFFHTMRYKS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 QDPRNPHNDRFVLSKGHAAPILYAVWAEAGFLAEAELLNLRKISSDLDGHPVPKQAFTDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QDPRNPHNDRFVLSKGHAAPILYAVWAEAGFLAEAELLNLRKISSDLDGHPVPKQAFTDV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 ATGSLGQGLGAACGMAYTGKYFDKASYRVYCLLGDGELSEGSVWEAMAFASIYKLDNLVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ATGSLGQGLGAACGMAYTGKYFDKASYRVYCLLGDGELSEGSVWEAMAFASIYKLDNLVA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 ILDINRLGQSDPAPLQHQMDIYQKRCEAFGWHAIIVDGHSVEELCKAFGQAKHQPTAIIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ILDINRLGQSDPAPLQHQMDIYQKRCEAFGWHAIIVDGHSVEELCKAFGQAKHQPTAIIA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 KTFKGRGITGVEDKESWHGKPLPKNMAEQIIQEIYSQIQSKKKILATPPQEDAPSVDIAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KTFKGRGITGVEDKESWHGKPLPKNMAEQIIQEIYSQIQSKKKILATPPQEDAPSVDIAN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 IRMPSLPSYKVGDKIATRKAYGQALAKLGHASDRIIALDGDTKNSTFSEIFKKEHPDRFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IRMPSLPSYKVGDKIATRKAYGQALAKLGHASDRIIALDGDTKNSTFSEIFKKEHPDRFI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 ECYIAEQNMVSIAVGCATRNRTVPFCSTFAAFFTRAFDQIRMAAISESNINLCGSHCGVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ECYIAEQNMVSIAVGCATRNRTVPFCSTFAAFFTRAFDQIRMAAISESNINLCGSHCGVS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE4 IGEDGPSQMALEDLAMFRSVPTSTVFYPSDGVATEKAVELAANTKGICFIRTSRPENAII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IGEDGPSQMALEDLAMFRSVPTSTVFYPSDGVATEKAVELAANTKGICFIRTSRPENAII
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE4 YNNNEDFQVGQAKVVLKSKDDQVTVIGAGVTLHEALAAAELLKKEKINIRVLDPFTIKPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YNNNEDFQVGQAKVVLKSKDDQVTVIGAGVTLHEALAAAELLKKEKINIRVLDPFTIKPL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE4 DRKLILDSARATKGRILTVEDHYYEGGIGEAVSSAVVGEPGITVTHLAVNRVPRSGKPAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DRKLILDSARATKGRILTVEDHYYEGGIGEAVSSAVVGEPGITVTHLAVNRVPRSGKPAE
550 560 570 580 590 600
610 620
pF1KE4 LLKMFGIDRDAIAQAVRGLITKA
:::::::::::::::::::::::
NP_001 LLKMFGIDRDAIAQAVRGLITKA
610 620
>>XP_011532356 (OMIM: 606781,617044) PREDICTED: transket (631 aa)
initn: 3122 init1: 3122 opt: 4066 Z-score: 4852.2 bits: 908.0 E(85289): 0
Smith-Waterman score: 4066; 98.7% identity (98.7% similar) in 631 aa overlap (1-623:1-631)
10 20 30 40 50 60
pF1KE4 MESYHKPDQQKLQALKDTANRLRISSIQATTAAGSGHPTSCCSAAEIMAVLFFHTMRYKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MESYHKPDQQKLQALKDTANRLRISSIQATTAAGSGHPTSCCSAAEIMAVLFFHTMRYKS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 QDPRNPHNDRFVLSKGHAAPILYAVWAEAGFLAEAELLNLRKISSDLDGHPVPKQAFTDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QDPRNPHNDRFVLSKGHAAPILYAVWAEAGFLAEAELLNLRKISSDLDGHPVPKQAFTDV
70 80 90 100 110 120
130 140 150 160 170
pF1KE4 ATGSLGQGLGAACGMAYTGKYFDKAS--------YRVYCLLGDGELSEGSVWEAMAFASI
:::::::::::::::::::::::::: ::::::::::::::::::::::::::
XP_011 ATGSLGQGLGAACGMAYTGKYFDKASLPSSWDYSYRVYCLLGDGELSEGSVWEAMAFASI
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE4 YKLDNLVAILDINRLGQSDPAPLQHQMDIYQKRCEAFGWHAIIVDGHSVEELCKAFGQAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YKLDNLVAILDINRLGQSDPAPLQHQMDIYQKRCEAFGWHAIIVDGHSVEELCKAFGQAK
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE4 HQPTAIIAKTFKGRGITGVEDKESWHGKPLPKNMAEQIIQEIYSQIQSKKKILATPPQED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HQPTAIIAKTFKGRGITGVEDKESWHGKPLPKNMAEQIIQEIYSQIQSKKKILATPPQED
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE4 APSVDIANIRMPSLPSYKVGDKIATRKAYGQALAKLGHASDRIIALDGDTKNSTFSEIFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 APSVDIANIRMPSLPSYKVGDKIATRKAYGQALAKLGHASDRIIALDGDTKNSTFSEIFK
310 320 330 340 350 360
360 370 380 390 400 410
pF1KE4 KEHPDRFIECYIAEQNMVSIAVGCATRNRTVPFCSTFAAFFTRAFDQIRMAAISESNINL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KEHPDRFIECYIAEQNMVSIAVGCATRNRTVPFCSTFAAFFTRAFDQIRMAAISESNINL
370 380 390 400 410 420
420 430 440 450 460 470
pF1KE4 CGSHCGVSIGEDGPSQMALEDLAMFRSVPTSTVFYPSDGVATEKAVELAANTKGICFIRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CGSHCGVSIGEDGPSQMALEDLAMFRSVPTSTVFYPSDGVATEKAVELAANTKGICFIRT
430 440 450 460 470 480
480 490 500 510 520 530
pF1KE4 SRPENAIIYNNNEDFQVGQAKVVLKSKDDQVTVIGAGVTLHEALAAAELLKKEKINIRVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SRPENAIIYNNNEDFQVGQAKVVLKSKDDQVTVIGAGVTLHEALAAAELLKKEKINIRVL
490 500 510 520 530 540
540 550 560 570 580 590
pF1KE4 DPFTIKPLDRKLILDSARATKGRILTVEDHYYEGGIGEAVSSAVVGEPGITVTHLAVNRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DPFTIKPLDRKLILDSARATKGRILTVEDHYYEGGIGEAVSSAVVGEPGITVTHLAVNRV
550 560 570 580 590 600
600 610 620
pF1KE4 PRSGKPAELLKMFGIDRDAIAQAVRGLITKA
:::::::::::::::::::::::::::::::
XP_011 PRSGKPAELLKMFGIDRDAIAQAVRGLITKA
610 620 630
>>NP_001244957 (OMIM: 606781,617044) transketolase isofo (631 aa)
initn: 3122 init1: 3122 opt: 4066 Z-score: 4852.2 bits: 908.0 E(85289): 0
Smith-Waterman score: 4066; 98.7% identity (98.7% similar) in 631 aa overlap (1-623:1-631)
10 20 30 40 50 60
pF1KE4 MESYHKPDQQKLQALKDTANRLRISSIQATTAAGSGHPTSCCSAAEIMAVLFFHTMRYKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MESYHKPDQQKLQALKDTANRLRISSIQATTAAGSGHPTSCCSAAEIMAVLFFHTMRYKS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 QDPRNPHNDRFVLSKGHAAPILYAVWAEAGFLAEAELLNLRKISSDLDGHPVPKQAFTDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QDPRNPHNDRFVLSKGHAAPILYAVWAEAGFLAEAELLNLRKISSDLDGHPVPKQAFTDV
70 80 90 100 110 120
130 140 150 160 170
pF1KE4 ATGSLGQGLGAACGMAYTGKYFDKAS--------YRVYCLLGDGELSEGSVWEAMAFASI
:::::::::::::::::::::::::: ::::::::::::::::::::::::::
NP_001 ATGSLGQGLGAACGMAYTGKYFDKASLPSSWDYSYRVYCLLGDGELSEGSVWEAMAFASI
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE4 YKLDNLVAILDINRLGQSDPAPLQHQMDIYQKRCEAFGWHAIIVDGHSVEELCKAFGQAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YKLDNLVAILDINRLGQSDPAPLQHQMDIYQKRCEAFGWHAIIVDGHSVEELCKAFGQAK
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE4 HQPTAIIAKTFKGRGITGVEDKESWHGKPLPKNMAEQIIQEIYSQIQSKKKILATPPQED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HQPTAIIAKTFKGRGITGVEDKESWHGKPLPKNMAEQIIQEIYSQIQSKKKILATPPQED
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE4 APSVDIANIRMPSLPSYKVGDKIATRKAYGQALAKLGHASDRIIALDGDTKNSTFSEIFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 APSVDIANIRMPSLPSYKVGDKIATRKAYGQALAKLGHASDRIIALDGDTKNSTFSEIFK
310 320 330 340 350 360
360 370 380 390 400 410
pF1KE4 KEHPDRFIECYIAEQNMVSIAVGCATRNRTVPFCSTFAAFFTRAFDQIRMAAISESNINL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KEHPDRFIECYIAEQNMVSIAVGCATRNRTVPFCSTFAAFFTRAFDQIRMAAISESNINL
370 380 390 400 410 420
420 430 440 450 460 470
pF1KE4 CGSHCGVSIGEDGPSQMALEDLAMFRSVPTSTVFYPSDGVATEKAVELAANTKGICFIRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CGSHCGVSIGEDGPSQMALEDLAMFRSVPTSTVFYPSDGVATEKAVELAANTKGICFIRT
430 440 450 460 470 480
480 490 500 510 520 530
pF1KE4 SRPENAIIYNNNEDFQVGQAKVVLKSKDDQVTVIGAGVTLHEALAAAELLKKEKINIRVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SRPENAIIYNNNEDFQVGQAKVVLKSKDDQVTVIGAGVTLHEALAAAELLKKEKINIRVL
490 500 510 520 530 540
540 550 560 570 580 590
pF1KE4 DPFTIKPLDRKLILDSARATKGRILTVEDHYYEGGIGEAVSSAVVGEPGITVTHLAVNRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DPFTIKPLDRKLILDSARATKGRILTVEDHYYEGGIGEAVSSAVVGEPGITVTHLAVNRV
550 560 570 580 590 600
600 610 620
pF1KE4 PRSGKPAELLKMFGIDRDAIAQAVRGLITKA
:::::::::::::::::::::::::::::::
NP_001 PRSGKPAELLKMFGIDRDAIAQAVRGLITKA
610 620 630
>>XP_011532357 (OMIM: 606781,617044) PREDICTED: transket (457 aa)
initn: 2976 init1: 2976 opt: 2976 Z-score: 3553.2 bits: 667.2 E(85289): 3.6e-191
Smith-Waterman score: 2976; 100.0% identity (100.0% similar) in 457 aa overlap (167-623:1-457)
140 150 160 170 180 190
pF1KE4 YTGKYFDKASYRVYCLLGDGELSEGSVWEAMAFASIYKLDNLVAILDINRLGQSDPAPLQ
::::::::::::::::::::::::::::::
XP_011 MAFASIYKLDNLVAILDINRLGQSDPAPLQ
10 20 30
200 210 220 230 240 250
pF1KE4 HQMDIYQKRCEAFGWHAIIVDGHSVEELCKAFGQAKHQPTAIIAKTFKGRGITGVEDKES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HQMDIYQKRCEAFGWHAIIVDGHSVEELCKAFGQAKHQPTAIIAKTFKGRGITGVEDKES
40 50 60 70 80 90
260 270 280 290 300 310
pF1KE4 WHGKPLPKNMAEQIIQEIYSQIQSKKKILATPPQEDAPSVDIANIRMPSLPSYKVGDKIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WHGKPLPKNMAEQIIQEIYSQIQSKKKILATPPQEDAPSVDIANIRMPSLPSYKVGDKIA
100 110 120 130 140 150
320 330 340 350 360 370
pF1KE4 TRKAYGQALAKLGHASDRIIALDGDTKNSTFSEIFKKEHPDRFIECYIAEQNMVSIAVGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TRKAYGQALAKLGHASDRIIALDGDTKNSTFSEIFKKEHPDRFIECYIAEQNMVSIAVGC
160 170 180 190 200 210
380 390 400 410 420 430
pF1KE4 ATRNRTVPFCSTFAAFFTRAFDQIRMAAISESNINLCGSHCGVSIGEDGPSQMALEDLAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ATRNRTVPFCSTFAAFFTRAFDQIRMAAISESNINLCGSHCGVSIGEDGPSQMALEDLAM
220 230 240 250 260 270
440 450 460 470 480 490
pF1KE4 FRSVPTSTVFYPSDGVATEKAVELAANTKGICFIRTSRPENAIIYNNNEDFQVGQAKVVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FRSVPTSTVFYPSDGVATEKAVELAANTKGICFIRTSRPENAIIYNNNEDFQVGQAKVVL
280 290 300 310 320 330
500 510 520 530 540 550
pF1KE4 KSKDDQVTVIGAGVTLHEALAAAELLKKEKINIRVLDPFTIKPLDRKLILDSARATKGRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KSKDDQVTVIGAGVTLHEALAAAELLKKEKINIRVLDPFTIKPLDRKLILDSARATKGRI
340 350 360 370 380 390
560 570 580 590 600 610
pF1KE4 LTVEDHYYEGGIGEAVSSAVVGEPGITVTHLAVNRVPRSGKPAELLKMFGIDRDAIAQAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTVEDHYYEGGIGEAVSSAVVGEPGITVTHLAVNRVPRSGKPAELLKMFGIDRDAIAQAV
400 410 420 430 440 450
620
pF1KE4 RGLITKA
:::::::
XP_011 RGLITKA
>>NP_001139406 (OMIM: 300044) transketolase-like protein (540 aa)
initn: 2351 init1: 1638 opt: 2218 Z-score: 2647.1 bits: 499.7 E(85289): 1.1e-140
Smith-Waterman score: 2276; 59.7% identity (80.9% similar) in 576 aa overlap (48-620:1-538)
20 30 40 50 60 70
pF1KE4 TANRLRISSIQATTAAGSGHPTSCCSAAEIMAVLFFHTMRYKSQDPRNPHNDRFVLSKGH
:.::::. ::::..::.:: ::::::.:
NP_001 MSVLFFYIMRYKQSDPENPDNDRFVLAK--
10 20
80 90 100 110 120 130
pF1KE4 AAPILYAVWAEAGFLAEAELLNLRKISSDLDGHPVPKQAFTDVATGSLGQGLGAACGMAY
. .:.::::: ::::::.::::::
NP_001 ------------------------------------RLSFVDVATGWLGQGLGVACGMAY
30 40 50
140 150 160 170 180 190
pF1KE4 TGKYFDKASYRVYCLLGDGELSEGSVWEAMAFASIYKLDNLVAILDINRLGQSDPAPLQH
::::::.:::::.::..::: ::::::::::::: :.:::::::.:.::::.: : .:
NP_001 TGKYFDRASYRVFCLMSDGESSEGSVWEAMAFASYYSLDNLVAIFDVNRLGHSGALPAEH
60 70 80 90 100 110
200 210 220 230 240 250
pF1KE4 QMDIYQKRCEAFGWHAIIVDGHSVEELCKAFGQA---KHQPTAIIAKTFKGRGITGVEDK
..:::.:::::::.. .:::..:: ::..: :: ::.:::..:::::::: ..::
NP_001 CINIYQRRCEAFGWNTYVVDGRDVEALCQVFWQASQVKHKPTAVVAKTFKGRGTPSIEDA
120 130 140 150 160 170
260 270 280 290 300 310
pF1KE4 ESWHGKPLPKNMAEQIIQEIYSQIQSKKKILATPPQEDAPSVDIANIRMPSLPSYKVGDK
::::.::.:.. :. ::. : ::::..... :: ::.: :.:...:: : :.:.::::
NP_001 ESWHAKPMPRERADAIIKLIESQIQTSRNLDPQPPIEDSPEVNITDVRMTSPPDYRVGDK
180 190 200 210 220 230
320 330 340 350 360 370
pF1KE4 IATRKAYGQALAKLGHASDRIIALDGDTKNSTFSEIFKKEHPDRFIECYIAEQNMVSIAV
:::::: : ::::::.:..:...:::::. :::::::.::.:.:::::..:::::::.:.
NP_001 IATRKACGLALAKLGYANNRVVVLDGDTRYSTFSEIFNKEYPERFIECFMAEQNMVSVAL
240 250 260 270 280 290
380 390 400 410 420 430
pF1KE4 GCATRNRTVPFCSTFAAFFTRAFDQIRMAAISESNINLCGSHCGVSIGEDGPSQMALEDL
:::.:.::. : ::::::.:::::.::.....:::::. :::::::.:.:: :::::::.
NP_001 GCASRGRTIAFASTFAAFLTRAFDHIRIGGLAESNINIIGSHCGVSVGDDGASQMALEDI
300 310 320 330 340 350
440 450 460 470 480 490
pF1KE4 AMFRSVPTSTVFYPSDGVATEKAVELAANTKGICFIRTSRPENAIIYNNNEDFQVGQAKV
::::..: :.:::.:.:.::.:: ::::.::.:::::.:::. .::. .: :..:::::
NP_001 AMFRTIPKCTIFYPTDAVSTEHAVALAANAKGMCFIRTTRPETMVIYTPQERFEIGQAKV
360 370 380 390 400 410
500 510 520 530 540 550
pF1KE4 VLKSKDDQVTVIGAGVTLHEALAAAELLKKEKINIRVLDPFTIKPLDRKLILDSARATKG
. . .:.:::::::.:..::::::. :.:. : :::.: ::::::: :..::.::.:
NP_001 LRHCVSDKVTVIGAGITVYEALAAADELSKQDIFIRVIDLFTIKPLDVATIVSSAKATEG
420 430 440 450 460 470
560 570 580 590 600 610
pF1KE4 RILTVEDHYYEGGIGEAVSSAVVGEPGITVTHLAVNRVPRSGKPAELLKMFGIDRDAIAQ
::.:::::: .::::::: .:: .: : : :::. ::.::: ::: :.::. :
NP_001 RIITVEDHYPQGGIGEAVCAAVSMDPDIQVHSLAVSGVPQSGKSEELLDMYGISARHIIV
480 490 500 510 520 530
620
pF1KE4 AVRGLITKA
::. ..
NP_001 AVKCMLLN
540
>>NP_001139405 (OMIM: 300044) transketolase-like protein (590 aa)
initn: 2375 init1: 1638 opt: 2218 Z-score: 2646.5 bits: 499.8 E(85289): 1.1e-140
Smith-Waterman score: 2380; 58.9% identity (80.4% similar) in 618 aa overlap (6-620:15-588)
10 20 30 40 50
pF1KE4 MESYHKPDQQKLQALKDTANRLRISSIQATTAAGSGHPTSCCSAAEIMAVL
.::. ::.:.: :.:::: ::.:: ...:: :..:::.::
NP_001 MADAEARAEFPEEARPDRGTLQVLQDMASRLRIHSIRATCSTSSG------SSSEIMSVL
10 20 30 40 50
60 70 80 90 100 110
pF1KE4 FFHTMRYKSQDPRNPHNDRFVLSKGHAAPILYAVWAEAGFLAEAELLNLRKISSDLDGHP
::. ::::..::.:: ::::::.:
NP_001 FFYIMRYKQSDPENPDNDRFVLAK------------------------------------
60 70
120 130 140 150 160 170
pF1KE4 VPKQAFTDVATGSLGQGLGAACGMAYTGKYFDKASYRVYCLLGDGELSEGSVWEAMAFAS
. .:.::::: ::::::.::::::::::::.:::::.::..::: :::::::::::::
NP_001 --RLSFVDVATGWLGQGLGVACGMAYTGKYFDRASYRVFCLMSDGESSEGSVWEAMAFAS
80 90 100 110 120 130
180 190 200 210 220 230
pF1KE4 IYKLDNLVAILDINRLGQSDPAPLQHQMDIYQKRCEAFGWHAIIVDGHSVEELCKAFGQA
:.:::::::.:.::::.: : .: ..:::.:::::::.. .:::..:: ::..: ::
NP_001 YYSLDNLVAIFDVNRLGHSGALPAEHCINIYQRRCEAFGWNTYVVDGRDVEALCQVFWQA
140 150 160 170 180 190
240 250 260 270 280
pF1KE4 ---KHQPTAIIAKTFKGRGITGVEDKESWHGKPLPKNMAEQIIQEIYSQIQSKKKILATP
::.:::..:::::::: ..:: ::::.::.:.. :. ::. : ::::..... :
NP_001 SQVKHKPTAVVAKTFKGRGTPSIEDAESWHAKPMPRERADAIIKLIESQIQTSRNLDPQP
200 210 220 230 240 250
290 300 310 320 330 340
pF1KE4 PQEDAPSVDIANIRMPSLPSYKVGDKIATRKAYGQALAKLGHASDRIIALDGDTKNSTFS
: ::.: :.:...:: : :.:.:::::::::: : ::::::.:..:...:::::. ::::
NP_001 PIEDSPEVNITDVRMTSPPDYRVGDKIATRKACGLALAKLGYANNRVVVLDGDTRYSTFS
260 270 280 290 300 310
350 360 370 380 390 400
pF1KE4 EIFKKEHPDRFIECYIAEQNMVSIAVGCATRNRTVPFCSTFAAFFTRAFDQIRMAAISES
:::.::.:.:::::..:::::::.:.:::.:.::. : ::::::.:::::.::.....::
NP_001 EIFNKEYPERFIECFMAEQNMVSVALGCASRGRTIAFASTFAAFLTRAFDHIRIGGLAES
320 330 340 350 360 370
410 420 430 440 450 460
pF1KE4 NINLCGSHCGVSIGEDGPSQMALEDLAMFRSVPTSTVFYPSDGVATEKAVELAANTKGIC
:::. :::::::.:.:: :::::::.::::..: :.:::.:.:.::.:: ::::.::.:
NP_001 NINIIGSHCGVSVGDDGASQMALEDIAMFRTIPKCTIFYPTDAVSTEHAVALAANAKGMC
380 390 400 410 420 430
470 480 490 500 510 520
pF1KE4 FIRTSRPENAIIYNNNEDFQVGQAKVVLKSKDDQVTVIGAGVTLHEALAAAELLKKEKIN
::::.:::. .::. .: :..:::::. . .:.:::::::.:..::::::. :.:. :
NP_001 FIRTTRPETMVIYTPQERFEIGQAKVLRHCVSDKVTVIGAGITVYEALAAADELSKQDIF
440 450 460 470 480 490
530 540 550 560 570 580
pF1KE4 IRVLDPFTIKPLDRKLILDSARATKGRILTVEDHYYEGGIGEAVSSAVVGEPGITVTHLA
:::.: ::::::: :..::.::.:::.:::::: .::::::: .:: .: : : ::
NP_001 IRVIDLFTIKPLDVATIVSSAKATEGRIITVEDHYPQGGIGEAVCAAVSMDPDIQVHSLA
500 510 520 530 540 550
590 600 610 620
pF1KE4 VNRVPRSGKPAELLKMFGIDRDAIAQAVRGLITKA
:. ::.::: ::: :.::. : ::. ..
NP_001 VSGVPQSGKSEELLDMYGISARHIIVAVKCMLLN
560 570 580 590
>>NP_036385 (OMIM: 300044) transketolase-like protein 1 (596 aa)
initn: 2519 init1: 1638 opt: 2218 Z-score: 2646.4 bits: 499.8 E(85289): 1.1e-140
Smith-Waterman score: 2444; 59.7% identity (81.2% similar) in 618 aa overlap (6-620:15-594)
10 20 30 40 50
pF1KE4 MESYHKPDQQKLQALKDTANRLRISSIQATTAAGSGHPTSCCSAAEIMAVL
.::. ::.:.: :.:::: ::.:: ...::::::: :..:::.::
NP_036 MADAEARAEFPEEARPDRGTLQVLQDMASRLRIHSIRATCSTSSGHPTSCSSSSEIMSVL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE4 FFHTMRYKSQDPRNPHNDRFVLSKGHAAPILYAVWAEAGFLAEAELLNLRKISSDLDGHP
::. ::::..::.:: ::::::.:
NP_036 FFYIMRYKQSDPENPDNDRFVLAK------------------------------------
70 80
120 130 140 150 160 170
pF1KE4 VPKQAFTDVATGSLGQGLGAACGMAYTGKYFDKASYRVYCLLGDGELSEGSVWEAMAFAS
. .:.::::: ::::::.::::::::::::.:::::.::..::: :::::::::::::
NP_036 --RLSFVDVATGWLGQGLGVACGMAYTGKYFDRASYRVFCLMSDGESSEGSVWEAMAFAS
90 100 110 120 130 140
180 190 200 210 220 230
pF1KE4 IYKLDNLVAILDINRLGQSDPAPLQHQMDIYQKRCEAFGWHAIIVDGHSVEELCKAFGQA
:.:::::::.:.::::.: : .: ..:::.:::::::.. .:::..:: ::..: ::
NP_036 YYSLDNLVAIFDVNRLGHSGALPAEHCINIYQRRCEAFGWNTYVVDGRDVEALCQVFWQA
150 160 170 180 190 200
240 250 260 270 280
pF1KE4 ---KHQPTAIIAKTFKGRGITGVEDKESWHGKPLPKNMAEQIIQEIYSQIQSKKKILATP
::.:::..:::::::: ..:: ::::.::.:.. :. ::. : ::::..... :
NP_036 SQVKHKPTAVVAKTFKGRGTPSIEDAESWHAKPMPRERADAIIKLIESQIQTSRNLDPQP
210 220 230 240 250 260
290 300 310 320 330 340
pF1KE4 PQEDAPSVDIANIRMPSLPSYKVGDKIATRKAYGQALAKLGHASDRIIALDGDTKNSTFS
: ::.: :.:...:: : :.:.:::::::::: : ::::::.:..:...:::::. ::::
NP_036 PIEDSPEVNITDVRMTSPPDYRVGDKIATRKACGLALAKLGYANNRVVVLDGDTRYSTFS
270 280 290 300 310 320
350 360 370 380 390 400
pF1KE4 EIFKKEHPDRFIECYIAEQNMVSIAVGCATRNRTVPFCSTFAAFFTRAFDQIRMAAISES
:::.::.:.:::::..:::::::.:.:::.:.::. : ::::::.:::::.::.....::
NP_036 EIFNKEYPERFIECFMAEQNMVSVALGCASRGRTIAFASTFAAFLTRAFDHIRIGGLAES
330 340 350 360 370 380
410 420 430 440 450 460
pF1KE4 NINLCGSHCGVSIGEDGPSQMALEDLAMFRSVPTSTVFYPSDGVATEKAVELAANTKGIC
:::. :::::::.:.:: :::::::.::::..: :.:::.:.:.::.:: ::::.::.:
NP_036 NINIIGSHCGVSVGDDGASQMALEDIAMFRTIPKCTIFYPTDAVSTEHAVALAANAKGMC
390 400 410 420 430 440
470 480 490 500 510 520
pF1KE4 FIRTSRPENAIIYNNNEDFQVGQAKVVLKSKDDQVTVIGAGVTLHEALAAAELLKKEKIN
::::.:::. .::. .: :..:::::. . .:.:::::::.:..::::::. :.:. :
NP_036 FIRTTRPETMVIYTPQERFEIGQAKVLRHCVSDKVTVIGAGITVYEALAAADELSKQDIF
450 460 470 480 490 500
530 540 550 560 570 580
pF1KE4 IRVLDPFTIKPLDRKLILDSARATKGRILTVEDHYYEGGIGEAVSSAVVGEPGITVTHLA
:::.: ::::::: :..::.::.:::.:::::: .::::::: .:: .: : : ::
NP_036 IRVIDLFTIKPLDVATIVSSAKATEGRIITVEDHYPQGGIGEAVCAAVSMDPDIQVHSLA
510 520 530 540 550 560
590 600 610 620
pF1KE4 VNRVPRSGKPAELLKMFGIDRDAIAQAVRGLITKA
:. ::.::: ::: :.::. : ::. ..
NP_036 VSGVPQSGKSEELLDMYGISARHIIVAVKCMLLN
570 580 590
>>NP_001166939 (OMIM: 179060,614111) pyruvate dehydrogen (341 aa)
initn: 144 init1: 100 opt: 173 Z-score: 208.8 bits: 47.9 E(85289): 6.8e-05
Smith-Waterman score: 182; 23.4% identity (52.3% similar) in 329 aa overlap (314-620:32-332)
290 300 310 320 330
pF1KE4 ILATPPQEDAPSVDIANIRMPSLPSYKVGDKIATRKAYGQALAKLGHASDRIIAL-----
....: : .:.. . . ..... :
NP_001 AAVSGLVRRPLREVSGLLKRRFHWTAPAALQVTVRDAINQGMDEELERDEKVFLLGEEVA
10 20 30 40 50 60
340 350 360 370 380 390
pF1KE4 --DGDTKNSTFSEIFKKEHPDRFIECYIAEQNMVSIAVGCATRNRTVPFCS--TFAAFFT
:: : : ..:: :.:. :.:.....:::: : . :.: :: :
NP_001 QYDGAYKVSR--GLWKKYGDKRIIDTPISEMGFAGIAVGAAMAG-LRPICEFMTFN-FSM
70 80 90 100 110
400 410 420 430 440 450
pF1KE4 RAFDQIRMAAISESNINLCGSHCGVSIGEDGPSQMALEDLAMFRSVPTSTVFYPSDGVAT
.:.::. .: . .. ::. .: . : . : : : . .
NP_001 QAIDQVINSAAKTYYMS------GVA------AQHSQCFAAWYGHCPGLKVVSPWN---S
120 130 140 150 160
460 470 480 490 500
pF1KE4 EKAVELAANTKGICFIRTSRP----ENAIIYN---------NNEDFQVGQAKVVLKSKDD
: : : .. :: . : :: ..:. ...:: . .:. .. .
NP_001 EDAKGLIKSA-----IRDNNPVVVLENELMYGVPFEFPPEAQSKDFLIPIGKAKIERQGT
170 180 190 200 210
510 520 530 540 550 560
pF1KE4 QVTVIGAGVTLHEALAAAELLKKEKINIRVLDPFTIKPLDRKLILDSARATKGRILTVED
..::.. . . . : :: .:.:: .. .:.. ::.:.: . : :. :. ...:::
NP_001 HITVVSHSRPVGHCLEAAAVLSKEGVECEVINMRTIRPMDMETIEASVMKTN-HLVTVEG
220 230 240 250 260 270
570 580 590 600 610 620
pF1KE4 HYYEGGIGEAVSSAVVGEPGITVTHLAVNRVPRSGKPAELLKMFGIDRDAIAQAVRGLIT
. . :.: . . .. :... . :: . : :. .. ..: : :. .:
NP_001 GWPQFGVGAEICARIMEGPAFNFLDAPAVRVTGADVPMPYAKI--LEDNSIPQ-VKDIIF
280 290 300 310 320 330
pF1KE4 KA
NP_001 AIKKTLNI
340
>>NP_001302465 (OMIM: 179060,614111) pyruvate dehydrogen (341 aa)
initn: 144 init1: 100 opt: 147 Z-score: 177.8 bits: 42.2 E(85289): 0.0036
Smith-Waterman score: 197; 24.3% identity (54.1% similar) in 305 aa overlap (333-620:40-332)
310 320 330 340 350 360
pF1KE4 MPSLPSYKVGDKIATRKAYGQALAKLGHASDRIIALDGDTKNSTFSEIFKKEHPDRFIEC
... :: : : ..:: :.:.
NP_001 RPLREVTVRDAINQGMDEELERDEKVFLLGEEVAQYDGAYKVS--RGLWKKYGDKRIIDT
10 20 30 40 50 60
370 380 390 400 410 420
pF1KE4 YIAEQNMVSIAVGCATRNRTVPFCS--TFAAFFTRAFDQIRMAAISESNINLCGSHCGVS
:.:.....:::: : . :.: :: : .:.::. .: . . . :. :
NP_001 PISEMGFAGIAVGAAMAG-LRPICEFMTFN-FSMQAIDQVINSAAK--TYYMSGGLQPVP
70 80 90 100 110 120
430 440 450 460 470
pF1KE4 IGEDGPSQMALEDLAMFRSVPTSTVFYPSDGVATEKAVELAANTKGI--CFIRTSRP---
: ::. : .: .: .. . :. . . . . ..::. :: . :
NP_001 IVFRGPNG-ASAGVAAQHSQCFAAWYGHCPGLKVVSPWN-SEDAKGLIKSAIRDNNPVVV
130 140 150 160 170 180
480 490 500 510 520
pF1KE4 -ENAIIYN---------NNEDFQVGQAKVVLKSKDDQVTVIGAGVTLHEALAAAELLKKE
:: ..:. ...:: . .:. .. . ..::.. . . . : :: .:.::
NP_001 LENELMYGVPFEFPPEAQSKDFLIPIGKAKIERQGTHITVVSHSRPVGHCLEAAAVLSKE
190 200 210 220 230 240
530 540 550 560 570 580
pF1KE4 KINIRVLDPFTIKPLDRKLILDSARATKGRILTVEDHYYEGGIGEAVSSAVVGEPGITVT
.. .:.. ::.:.: . : :. :. ...::: . . :.: . . .. :...
NP_001 GVECEVINMRTIRPMDMETIEASVMKTN-HLVTVEGGWPQFGVGAEICARIMEGPAFNFL
250 260 270 280 290 300
590 600 610 620
pF1KE4 HLAVNRVPRSGKPAELLKMFGIDRDAIAQAVRGLITKA
. :: . : :. .. ..: : :. .:
NP_001 DAPAVRVTGADVPMPYAKI--LEDNSIPQ-VKDIIFAIKKTLNI
310 320 330 340
623 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 00:07:50 2016 done: Sun Nov 6 00:07:51 2016
Total Scan time: 10.060 Total Display time: 0.110
Function used was FASTA [36.3.4 Apr, 2011]