Result of FASTA (omim) for
pFN21AE4536
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE4536, 603 aa
1>>>pF1KE4536 603 - 603 aa - 603 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.0464+/-0.000359; mu= 21.0328+/- 0.022
mean_var=68.2868+/-13.957, 0's: 0 Z-trim(113.6): 38 B-trim: 710 in 1/56
Lambda= 0.155205
statistics sampled from 23013 (23050) to 23013 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.639), E-opt: 0.2 (0.27), width: 16
Scan time: 9.270
The best scores are: opt bits E(85289)
NP_000778 (OMIM: 223360,609312) dopamine beta-hydr ( 617) 4137 935.6 0
NP_056344 (OMIM: 609000) DBH-like monooxygenase pr ( 613) 1053 245.0 5.4e-64
XP_016866203 (OMIM: 609000) PREDICTED: DBH-like mo ( 578) 946 221.1 8.5e-57
XP_016866204 (OMIM: 609000) PREDICTED: DBH-like mo ( 526) 944 220.6 1.1e-56
XP_016865005 (OMIM: 170270) PREDICTED: peptidyl-gl ( 780) 167 46.7 0.00035
XP_016865004 (OMIM: 170270) PREDICTED: peptidyl-gl ( 798) 167 46.7 0.00035
XP_016865003 (OMIM: 170270) PREDICTED: peptidyl-gl ( 799) 167 46.7 0.00035
XP_016865002 (OMIM: 170270) PREDICTED: peptidyl-gl ( 819) 167 46.7 0.00036
XP_016865001 (OMIM: 170270) PREDICTED: peptidyl-gl ( 837) 167 46.7 0.00036
XP_016865000 (OMIM: 170270) PREDICTED: peptidyl-gl ( 838) 167 46.7 0.00037
XP_016864999 (OMIM: 170270) PREDICTED: peptidyl-gl ( 848) 167 46.7 0.00037
XP_016864998 (OMIM: 170270) PREDICTED: peptidyl-gl ( 865) 167 46.8 0.00037
NP_620176 (OMIM: 170270) peptidyl-glycine alpha-am ( 866) 167 46.8 0.00037
XP_016864997 (OMIM: 170270) PREDICTED: peptidyl-gl ( 866) 167 46.8 0.00037
XP_016864996 (OMIM: 170270) PREDICTED: peptidyl-gl ( 867) 167 46.8 0.00038
NP_620177 (OMIM: 170270) peptidyl-glycine alpha-am ( 887) 167 46.8 0.00038
NP_620121 (OMIM: 170270) peptidyl-glycine alpha-am ( 905) 167 46.8 0.00039
XP_016864994 (OMIM: 170270) PREDICTED: peptidyl-gl ( 905) 167 46.8 0.00039
XP_016864995 (OMIM: 170270) PREDICTED: peptidyl-gl ( 905) 167 46.8 0.00039
XP_016864993 (OMIM: 170270) PREDICTED: peptidyl-gl ( 906) 167 46.8 0.00039
XP_016864992 (OMIM: 170270) PREDICTED: peptidyl-gl ( 923) 167 46.8 0.00039
XP_016864991 (OMIM: 170270) PREDICTED: peptidyl-gl ( 924) 167 46.8 0.00039
XP_016864990 (OMIM: 170270) PREDICTED: peptidyl-gl ( 955) 167 46.8 0.0004
XP_016864989 (OMIM: 170270) PREDICTED: peptidyl-gl ( 972) 167 46.8 0.00041
XP_016864987 (OMIM: 170270) PREDICTED: peptidyl-gl ( 973) 167 46.8 0.00041
XP_016864988 (OMIM: 170270) PREDICTED: peptidyl-gl ( 973) 167 46.8 0.00041
NP_001170777 (OMIM: 170270) peptidyl-glycine alpha ( 973) 167 46.8 0.00041
XP_016864986 (OMIM: 170270) PREDICTED: peptidyl-gl ( 974) 167 46.8 0.00041
NP_000910 (OMIM: 170270) peptidyl-glycine alpha-am ( 974) 167 46.8 0.00041
XP_016864985 (OMIM: 170270) PREDICTED: peptidyl-gl ( 990) 167 46.8 0.00042
XP_016864984 (OMIM: 170270) PREDICTED: peptidyl-gl ( 991) 167 46.8 0.00042
NP_001306872 (OMIM: 170270) peptidyl-glycine alpha ( 991) 167 46.8 0.00042
XP_011541721 (OMIM: 170270) PREDICTED: peptidyl-gl ( 992) 167 46.8 0.00042
>>NP_000778 (OMIM: 223360,609312) dopamine beta-hydroxyl (617 aa)
initn: 4137 init1: 4137 opt: 4137 Z-score: 5001.8 bits: 935.6 E(85289): 0
Smith-Waterman score: 4137; 100.0% identity (100.0% similar) in 603 aa overlap (1-603:15-617)
10 20 30 40
pF1KE4 MREAAFMYSTAVAIFLVILVAALQGSAPRESPLPYHIPLDPEGSLE
::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MPALSRWASLPGPSMREAAFMYSTAVAIFLVILVAALQGSAPRESPLPYHIPLDPEGSLE
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE4 LSWNVSYTQEAIHFQLLVRRLKAGVLFGMSDRGELENADLVVLWTDGDTAYFADAWSDQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LSWNVSYTQEAIHFQLLVRRLKAGVLFGMSDRGELENADLVVLWTDGDTAYFADAWSDQK
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE4 GQIHLDPQQDYQLLQVQRTPEGLTLLFKRPFGTCDPKDYLIEDGTVHLVYGILEEPFRSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 GQIHLDPQQDYQLLQVQRTPEGLTLLFKRPFGTCDPKDYLIEDGTVHLVYGILEEPFRSL
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE4 EAINGSGLQMGLQRVQLLKPNIPEPELPSDACTMEVQAPNIQIPSQETTYWCYIKELPKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 EAINGSGLQMGLQRVQLLKPNIPEPELPSDACTMEVQAPNIQIPSQETTYWCYIKELPKG
190 200 210 220 230 240
230 240 250 260 270 280
pF1KE4 FSRHHIIKYEPIVTKGNEALVHHMEVFQCAPEMDSVPHFSGPCDSKMKPDRLNYCRHVLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 FSRHHIIKYEPIVTKGNEALVHHMEVFQCAPEMDSVPHFSGPCDSKMKPDRLNYCRHVLA
250 260 270 280 290 300
290 300 310 320 330 340
pF1KE4 AWALGAKAFYYPEEAGLAFGGPGSSRYLRLEVHYHNPLVIEGRNDSSGIRLYYTAKLRRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 AWALGAKAFYYPEEAGLAFGGPGSSRYLRLEVHYHNPLVIEGRNDSSGIRLYYTAKLRRF
310 320 330 340 350 360
350 360 370 380 390 400
pF1KE4 NAGIMELGLVYTPVMAIPPRETAFILTGYCTDKCTQLALPPSGIHIFASQLHTHLTGRKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 NAGIMELGLVYTPVMAIPPRETAFILTGYCTDKCTQLALPPSGIHIFASQLHTHLTGRKV
370 380 390 400 410 420
410 420 430 440 450 460
pF1KE4 VTVLVRDGREWEIVNQDNHYSPHFQEIRMLKKVVSVHPGDVLITSCTYNTEDRELATVGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VTVLVRDGREWEIVNQDNHYSPHFQEIRMLKKVVSVHPGDVLITSCTYNTEDRELATVGG
430 440 450 460 470 480
470 480 490 500 510 520
pF1KE4 FGILEEMCVNYVHYYPQTQLELCKSAVDAGFLQKYFHLINRFNNEDVCTCPQASVSQQFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 FGILEEMCVNYVHYYPQTQLELCKSAVDAGFLQKYFHLINRFNNEDVCTCPQASVSQQFT
490 500 510 520 530 540
530 540 550 560 570 580
pF1KE4 SVPWNSFNRDVLKALYSFAPISMHCNKSSAVRFQGEWNLQPLPKVISTLEEPTPQCPTSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SVPWNSFNRDVLKALYSFAPISMHCNKSSAVRFQGEWNLQPLPKVISTLEEPTPQCPTSQ
550 560 570 580 590 600
590 600
pF1KE4 GRSPAGPTVVSIGGGKG
:::::::::::::::::
NP_000 GRSPAGPTVVSIGGGKG
610
>>NP_056344 (OMIM: 609000) DBH-like monooxygenase protei (613 aa)
initn: 663 init1: 343 opt: 1053 Z-score: 1269.8 bits: 245.0 E(85289): 5.4e-64
Smith-Waterman score: 1069; 33.1% identity (59.7% similar) in 595 aa overlap (16-589:6-584)
10 20 30 40 50
pF1KE4 MREAAFMYSTAVAIFLVILVAALQGSAPRES--PLPYHIPLDPEGSLELSWNVSYTQEAI
:..: . : :.: : :.. :: ::. :.:. .: :
NP_056 MCCWPLLLLWGLLPGTAAGGSGRTYPHRTLLDSEGKYWLGWSQRGSQ--I
10 20 30 40
60 70 80 90 100 110
pF1KE4 HFQLLVRRLKAG-VLFGMSDRGELENADLVVLWTDGDTAYFADAWSDQKGQIHLDPQQDY
:.: :: :: : ::.: : . .::.:: . :. : ... . ... : ::::
NP_056 AFRLQVRT--AGYVGFGFSPTGAMASADIVVGGVAHGRPYLQDYFTNANRELKKDAQQDY
50 60 70 80 90 100
120 130 140 150 160 170
pF1KE4 QLLQVQRTPEGLTLLFKRPFGTCDPKDYLIEDGTVHLVYGILEEPFRSLEA-INGSGLQM
.: .... . : : . ::: .: : :.::..... .: . :: . .
NP_056 HLEYAMENSTHTIIEFTRELHTCDINDKSITDSTVRVIWAYHHED--AGEAGPKYHDSNR
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE4 GLQRVQLLKPNIPEPELPSDACTMEVQAPNIQIPSQETTYWCYIKELPKGFSRHHIIKYE
: . ..::.:. : . ... .. ::...::::: . ..: .::.:: :
NP_056 GTKSLRLLNPE-KTSVLSTALPYFDLVNQDVPIPNKDTTYWCQMFKIPVFQEKHHVIKVE
170 180 190 200 210 220
240 250 260 270 280 290
pF1KE4 PIVTKGNEALVHHMEVFQCAPEM-DSVPHFSGPCDSKMKPDRLNYCRHVLAAWALGAKAF
:.. .:.:.::::. ..::. .. ::: . . : :: . :. :. :::.:...:
NP_056 PVIQRGHESLVHHILLYQCSNNFNDSVLESGHECYHPNMPDAFLTCETVIFAWAIGGEGF
230 240 250 260 270 280
300 310 320 330 340 350
pF1KE4 YYPEEAGLAFGGPGSSRYLRLEVHYHNPLVIEGRNDSSGIRLYYTAKLRRFNAGIMELGL
:: ..::..: : . .:. ::::: :: :: :.::.::.:: .:...::..: ::
NP_056 SYPPHVGLSLGTPLDPHYVLLEVHYDNPTYEEGLIDNSGLRLFYTMDIRKYDAGVIEAGL
290 300 310 320 330 340
360 370 380 390 400 410
pF1KE4 VYTPVMAIPPRETAFILTGYCTDKCTQLALP---PSGIHIFASQLHTHLTGRKVVTVLVR
. .::: : :.:: .: . :: :::::.:: ::.::.:: . :
NP_056 WVSLFHTIPPGMPEFQSEGHCTLECLEEALEAEKPSGIHVFAVLLHAHLAGRGIRLRHFR
350 360 370 380 390 400
420 430 440 450 460 470
pF1KE4 DGREWEIVNQDNHYSPHFQEIRMLKKVVSVHPGDVLITSCTYNTEDRELATVGGFGILEE
:.: ... :. .. .:::...::. .. ::: ::: : :::.:: : ::.. :
NP_056 KGKEMKLLAYDDDFDFNFQEFQYLKEEQTILPGDNLITECRYNTKDRAEMTWGGLSTRSE
410 420 430 440 450 460
480 490 500 510 520
pF1KE4 MCVNYVHYYPQTQLELCKSAVDAGFLQKYFHLINRFNNED----VCTCPQASVSQQFTSV
::..:. :::. .: : : : ... . . . . :. . .: ..
NP_056 MCLSYLLYYPRINLTRCASIPDIMEQLQFIGVKEIYRPVTTWPFIIKSPKQYKNLSFMDA
470 480 490 500 510 520
530 540 550 560 570
pF1KE4 ----PWN-----SFNRDVLKALYSFAPISMHCNKSSAVRFQGEWNLQPLPKVISTLEEPT
:. :::. ::. :....:.:.. ..::..: . . .:.:
NP_056 MNKFKWTKKEGLSFNKLVLS-----LPVNVRCSKTD----NAEWSIQGMTALPPDIERPY
530 540 550 560 570
580 590 600
pF1KE4 PQCPTSQGRSPAGPTVVSIGGGKG
: : :
NP_056 KAEPLVCGTSSSSSLHRDFSINLLVCLLLLSCTLSTKSL
580 590 600 610
>>XP_016866203 (OMIM: 609000) PREDICTED: DBH-like monoox (578 aa)
initn: 600 init1: 343 opt: 946 Z-score: 1140.7 bits: 221.1 E(85289): 8.5e-57
Smith-Waterman score: 962; 32.4% identity (60.1% similar) in 521 aa overlap (90-589:41-549)
60 70 80 90 100 110
pF1KE4 FQLLVRRLKAGVLFGMSDRGELENADLVVLWTD-GDTAYF--ADAWSDQKGQIHLDPQQD
:.. :. : : ... . ... : :::
XP_016 GLLPGTAAGGSGRTYPHRTLLDSEGKYWLGWSQRGSQIAFRLQDYFTNANRELKKDAQQD
20 30 40 50 60 70
120 130 140 150 160 170
pF1KE4 YQLLQVQRTPEGLTLLFKRPFGTCDPKDYLIEDGTVHLVYGILEEPFRSLEA-INGSGLQ
:.: .... . : : . ::: .: : :.::..... .: . :: . .
XP_016 YHLEYAMENSTHTIIEFTRELHTCDINDKSITDSTVRVIWAYHHED--AGEAGPKYHDSN
80 90 100 110 120
180 190 200 210 220 230
pF1KE4 MGLQRVQLLKPNIPEPELPSDACTMEVQAPNIQIPSQETTYWCYIKELPKGFSRHHIIKY
: . ..::.:. : . ... .. ::...::::: . ..: .::.::
XP_016 RGTKSLRLLNPE-KTSVLSTALPYFDLVNQDVPIPNKDTTYWCQMFKIPVFQEKHHVIKV
130 140 150 160 170 180
240 250 260 270 280 290
pF1KE4 EPIVTKGNEALVHHMEVFQCAPEM-DSVPHFSGPCDSKMKPDRLNYCRHVLAAWALGAKA
::.. .:.:.::::. ..::. .. ::: . . : :: . :. :. :::.:...
XP_016 EPVIQRGHESLVHHILLYQCSNNFNDSVLESGHECYHPNMPDAFLTCETVIFAWAIGGEG
190 200 210 220 230 240
300 310 320 330 340 350
pF1KE4 FYYPEEAGLAFGGPGSSRYLRLEVHYHNPLVIEGRNDSSGIRLYYTAKLRRFNAGIMELG
: :: ..::..: : . .:. ::::: :: :: :.::.::.:: .:...::..: :
XP_016 FSYPPHVGLSLGTPLDPHYVLLEVHYDNPTYEEGLIDNSGLRLFYTMDIRKYDAGVIEAG
250 260 270 280 290 300
360 370 380 390 400 410
pF1KE4 LVYTPVMAIPPRETAFILTGYCTDKCTQLALP---PSGIHIFASQLHTHLTGRKVVTVLV
: . .::: : :.:: .: . :: :::::.:: ::.::.:: .
XP_016 LWVSLFHTIPPGMPEFQSEGHCTLECLEEALEAEKPSGIHVFAVLLHAHLAGRGIRLRHF
310 320 330 340 350 360
420 430 440 450 460 470
pF1KE4 RDGREWEIVNQDNHYSPHFQEIRMLKKVVSVHPGDVLITSCTYNTEDRELATVGGFGILE
: :.: ... :. .. .:::...::. .. ::: ::: : :::.:: : ::..
XP_016 RKGKEMKLLAYDDDFDFNFQEFQYLKEEQTILPGDNLITECRYNTKDRAEMTWGGLSTRS
370 380 390 400 410 420
480 490 500 510 520
pF1KE4 EMCVNYVHYYPQTQLELCKSAVDAGFLQKYFHLINRFNNED----VCTCPQASVSQQFTS
:::..:. :::. .: : : : ... . . . . :. . .: .
XP_016 EMCLSYLLYYPRINLTRCASIPDIMEQLQFIGVKEIYRPVTTWPFIIKSPKQYKNLSFMD
430 440 450 460 470 480
530 540 550 560 570
pF1KE4 V----PWN-----SFNRDVLKALYSFAPISMHCNKSSAVRFQGEWNLQPLPKVISTLEEP
. :. :::. ::. :....:.:.. ..::..: . . .:.:
XP_016 AMNKFKWTKKEGLSFNKLVLSL-----PVNVRCSKTD----NAEWSIQGMTALPPDIERP
490 500 510 520 530
580 590 600
pF1KE4 TPQCPTSQGRSPAGPTVVSIGGGKG
: : :
XP_016 YKAEPLVCGTSSSSSLHRDFSINLLVCLLLLSCTLSTKSL
540 550 560 570
>>XP_016866204 (OMIM: 609000) PREDICTED: DBH-like monoox (526 aa)
initn: 600 init1: 343 opt: 944 Z-score: 1138.8 bits: 220.6 E(85289): 1.1e-56
Smith-Waterman score: 960; 32.7% identity (60.4% similar) in 508 aa overlap (100-589:2-497)
70 80 90 100 110 120
pF1KE4 GVLFGMSDRGELENADLVVLWTDGDTAYFADAWSDQKGQIHLDPQQDYQLLQVQRTPEGL
: ... . ... : ::::.: ....
XP_016 MDYFTNANRELKKDAQQDYHLEYAMENSTHT
10 20 30
130 140 150 160 170 180
pF1KE4 TLLFKRPFGTCDPKDYLIEDGTVHLVYGILEEPFRSLEA-INGSGLQMGLQRVQLLKPNI
. : : . ::: .: : :.::..... .: . :: . . : . ..::.:.
XP_016 IIEFTRELHTCDINDKSITDSTVRVIWAYHHED--AGEAGPKYHDSNRGTKSLRLLNPE-
40 50 60 70 80
190 200 210 220 230 240
pF1KE4 PEPELPSDACTMEVQAPNIQIPSQETTYWCYIKELPKGFSRHHIIKYEPIVTKGNEALVH
: . ... .. ::...::::: . ..: .::.:: ::.. .:.:.:::
XP_016 KTSVLSTALPYFDLVNQDVPIPNKDTTYWCQMFKIPVFQEKHHVIKVEPVIQRGHESLVH
90 100 110 120 130 140
250 260 270 280 290 300
pF1KE4 HMEVFQCAPEM-DSVPHFSGPCDSKMKPDRLNYCRHVLAAWALGAKAFYYPEEAGLAFGG
:. ..::. .. ::: . . : :: . :. :. :::.:...: :: ..::..:
XP_016 HILLYQCSNNFNDSVLESGHECYHPNMPDAFLTCETVIFAWAIGGEGFSYPPHVGLSLGT
150 160 170 180 190 200
310 320 330 340 350 360
pF1KE4 PGSSRYLRLEVHYHNPLVIEGRNDSSGIRLYYTAKLRRFNAGIMELGLVYTPVMAIPPRE
: . .:. ::::: :: :: :.::.::.:: .:...::..: :: . .:::
XP_016 PLDPHYVLLEVHYDNPTYEEGLIDNSGLRLFYTMDIRKYDAGVIEAGLWVSLFHTIPPGM
210 220 230 240 250 260
370 380 390 400 410 420
pF1KE4 TAFILTGYCTDKCTQLALP---PSGIHIFASQLHTHLTGRKVVTVLVRDGREWEIVNQDN
: :.:: .: . :: :::::.:: ::.::.:: . : :.: ... :.
XP_016 PEFQSEGHCTLECLEEALEAEKPSGIHVFAVLLHAHLAGRGIRLRHFRKGKEMKLLAYDD
270 280 290 300 310 320
430 440 450 460 470 480
pF1KE4 HYSPHFQEIRMLKKVVSVHPGDVLITSCTYNTEDRELATVGGFGILEEMCVNYVHYYPQT
.. .:::...::. .. ::: ::: : :::.:: : ::.. :::..:. :::.
XP_016 DFDFNFQEFQYLKEEQTILPGDNLITECRYNTKDRAEMTWGGLSTRSEMCLSYLLYYPRI
330 340 350 360 370 380
490 500 510 520 530
pF1KE4 QLELCKSAVDAGFLQKYFHLINRFNNED----VCTCPQASVSQQFTSV----PWN-----
.: : : : ... . . . . :. . .: .. :.
XP_016 NLTRCASIPDIMEQLQFIGVKEIYRPVTTWPFIIKSPKQYKNLSFMDAMNKFKWTKKEGL
390 400 410 420 430 440
540 550 560 570 580 590
pF1KE4 SFNRDVLKALYSFAPISMHCNKSSAVRFQGEWNLQPLPKVISTLEEPTPQCPTSQGRSPA
:::. ::. :....:.:.. ..::..: . . .:.: : : :
XP_016 SFNKLVLSL-----PVNVRCSKTD----NAEWSIQGMTALPPDIERPYKAEPLVCGTSSS
450 460 470 480 490
600
pF1KE4 GPTVVSIGGGKG
XP_016 SSLHRDFSINLLVCLLLLSCTLSTKSL
500 510 520
>>XP_016865005 (OMIM: 170270) PREDICTED: peptidyl-glycin (780 aa)
initn: 259 init1: 100 opt: 167 Z-score: 196.2 bits: 46.7 E(85289): 0.00035
Smith-Waterman score: 368; 28.4% identity (54.2% similar) in 306 aa overlap (185-485:47-321)
160 170 180 190 200 210
pF1KE4 VYGILEEPFRSLEAINGSGLQMGLQRVQLLKPNIPEPELPSDACTMEVQAPNIQIPSQET
.: .: . :. ..... :.. :.:
XP_016 SCLAFRSPLSVFKRFKETTRPFSNECLGTTRPVVP---IDSSDFALDIRMPGVT-PKQSD
20 30 40 50 60 70
220 230 240 250 260 270
pF1KE4 TYWCYIKELPKGFSRHHIIKYEPIVTKGNEALVHHMEVFQCAPEMDSVPHFSGP---CDS
::.:. ..: . .: ..: ... :::: .: : ..: .: ::
XP_016 TYFCMSMRIPVD-EEAFVIDFKP---RASMDTVHHMLLFGC-----NMPSSTGSYWFCDE
80 90 100 110 120
280 290 300 310 320 330
pF1KE4 KMKPDRLNYCRHVLAAWALGAKAFYYPEEAGLAFGGPGSSRYLRLEVHYHNPLVIEGRN-
:. : .: ::: .: :. .:. :: .:.:. :.::: . ... :
XP_016 GTCTDKAN----ILYAWARNAPPTRLPKGVGFRVGGETGSKYFVLQVHYGDISAFRDNNK
130 140 150 160 170
340 350 360 370 380 390
pF1KE4 DSSGIRLYYTAKLRRFNAGIMELGLVYTPVMAIPPRETAFILTGYCTDKCTQLALPPSGI
: ::. :. : . . ::.. . : : .:: : . : : : .
XP_016 DCSGVSLHLTRLPQPLIAGMYLMMSVDT---VIPAGEKVVNSDISCHYK----NYP---M
180 190 200 210 220
400 410 420 430 440 450
pF1KE4 HIFASQLHTHLTGRKVVTVLVRDGREWEIVNQDNHYSPHFQEIRMLKKVVSVHPGDVLIT
:.:: ..::: :. : ::.: .: ...... : : . . . :.: ::.: .
XP_016 HVFAYRVHTHHLGKVVSGYRVRNG-QWTLIGRQSPQLP--QAFYPVGHPVDVSFGDLLAA
230 240 250 260 270 280
460 470 480 490 500
pF1KE4 SCTYNTEDRELAT-VGGFGILEEMCVNYVHYYPQTQLELCKSAVDAGFLQKYFHLINRFN
:... : : :: .:: . .::: :. :: ...
XP_016 RCVFTGEGRTEATHIGGTSS-DEMCNLYIMYYMEAKHAVSFMTCTQNVAPDMFRTIPPEA
290 300 310 320 330 340
510 520 530 540 550 560
pF1KE4 NEDVCTCPQASVSQQFTSVPWNSFNRDVLKALYSFAPISMHCNKSSAVRFQGEWNLQPLP
XP_016 NIPIPVKSDMVMMHEHHKETEYKDKIPLLQQPKREEEEVLDQDFHMEEALDWPGVYLLPG
350 360 370 380 390 400
>>XP_016865004 (OMIM: 170270) PREDICTED: peptidyl-glycin (798 aa)
initn: 259 init1: 100 opt: 167 Z-score: 196.0 bits: 46.7 E(85289): 0.00035
Smith-Waterman score: 368; 28.4% identity (54.2% similar) in 306 aa overlap (185-485:47-321)
160 170 180 190 200 210
pF1KE4 VYGILEEPFRSLEAINGSGLQMGLQRVQLLKPNIPEPELPSDACTMEVQAPNIQIPSQET
.: .: . :. ..... :.. :.:
XP_016 SCLAFRSPLSVFKRFKETTRPFSNECLGTTRPVVP---IDSSDFALDIRMPGVT-PKQSD
20 30 40 50 60 70
220 230 240 250 260 270
pF1KE4 TYWCYIKELPKGFSRHHIIKYEPIVTKGNEALVHHMEVFQCAPEMDSVPHFSGP---CDS
::.:. ..: . .: ..: ... :::: .: : ..: .: ::
XP_016 TYFCMSMRIPVD-EEAFVIDFKP---RASMDTVHHMLLFGC-----NMPSSTGSYWFCDE
80 90 100 110 120
280 290 300 310 320 330
pF1KE4 KMKPDRLNYCRHVLAAWALGAKAFYYPEEAGLAFGGPGSSRYLRLEVHYHNPLVIEGRN-
:. : .: ::: .: :. .:. :: .:.:. :.::: . ... :
XP_016 GTCTDKAN----ILYAWARNAPPTRLPKGVGFRVGGETGSKYFVLQVHYGDISAFRDNNK
130 140 150 160 170
340 350 360 370 380 390
pF1KE4 DSSGIRLYYTAKLRRFNAGIMELGLVYTPVMAIPPRETAFILTGYCTDKCTQLALPPSGI
: ::. :. : . . ::.. . : : .:: : . : : : .
XP_016 DCSGVSLHLTRLPQPLIAGMYLMMSVDT---VIPAGEKVVNSDISCHYK----NYP---M
180 190 200 210 220
400 410 420 430 440 450
pF1KE4 HIFASQLHTHLTGRKVVTVLVRDGREWEIVNQDNHYSPHFQEIRMLKKVVSVHPGDVLIT
:.:: ..::: :. : ::.: .: ...... : : . . . :.: ::.: .
XP_016 HVFAYRVHTHHLGKVVSGYRVRNG-QWTLIGRQSPQLP--QAFYPVGHPVDVSFGDLLAA
230 240 250 260 270 280
460 470 480 490 500
pF1KE4 SCTYNTEDRELAT-VGGFGILEEMCVNYVHYYPQTQLELCKSAVDAGFLQKYFHLINRFN
:... : : :: .:: . .::: :. :: ...
XP_016 RCVFTGEGRTEATHIGGTSS-DEMCNLYIMYYMEAKHAVSFMTCTQNVAPDMFRTIPPEA
290 300 310 320 330 340
510 520 530 540 550 560
pF1KE4 NEDVCTCPQASVSQQFTSVPWNSFNRDVLKALYSFAPISMHCNKSSAVRFQGEWNLQPLP
XP_016 NIPIPVKSDMVMMHEHHKETEYKDKIPLLQQPKREEEEVLDQDFHMEEALDWPGVYLLPG
350 360 370 380 390 400
>>XP_016865003 (OMIM: 170270) PREDICTED: peptidyl-glycin (799 aa)
initn: 259 init1: 100 opt: 167 Z-score: 196.0 bits: 46.7 E(85289): 0.00035
Smith-Waterman score: 368; 28.4% identity (54.2% similar) in 306 aa overlap (185-485:47-321)
160 170 180 190 200 210
pF1KE4 VYGILEEPFRSLEAINGSGLQMGLQRVQLLKPNIPEPELPSDACTMEVQAPNIQIPSQET
.: .: . :. ..... :.. :.:
XP_016 SCLAFRSPLSVFKRFKETTRPFSNECLGTTRPVVP---IDSSDFALDIRMPGVT-PKQSD
20 30 40 50 60 70
220 230 240 250 260 270
pF1KE4 TYWCYIKELPKGFSRHHIIKYEPIVTKGNEALVHHMEVFQCAPEMDSVPHFSGP---CDS
::.:. ..: . .: ..: ... :::: .: : ..: .: ::
XP_016 TYFCMSMRIPVD-EEAFVIDFKP---RASMDTVHHMLLFGC-----NMPSSTGSYWFCDE
80 90 100 110 120
280 290 300 310 320 330
pF1KE4 KMKPDRLNYCRHVLAAWALGAKAFYYPEEAGLAFGGPGSSRYLRLEVHYHNPLVIEGRN-
:. : .: ::: .: :. .:. :: .:.:. :.::: . ... :
XP_016 GTCTDKAN----ILYAWARNAPPTRLPKGVGFRVGGETGSKYFVLQVHYGDISAFRDNNK
130 140 150 160 170
340 350 360 370 380 390
pF1KE4 DSSGIRLYYTAKLRRFNAGIMELGLVYTPVMAIPPRETAFILTGYCTDKCTQLALPPSGI
: ::. :. : . . ::.. . : : .:: : . : : : .
XP_016 DCSGVSLHLTRLPQPLIAGMYLMMSVDT---VIPAGEKVVNSDISCHYK----NYP---M
180 190 200 210 220
400 410 420 430 440 450
pF1KE4 HIFASQLHTHLTGRKVVTVLVRDGREWEIVNQDNHYSPHFQEIRMLKKVVSVHPGDVLIT
:.:: ..::: :. : ::.: .: ...... : : . . . :.: ::.: .
XP_016 HVFAYRVHTHHLGKVVSGYRVRNG-QWTLIGRQSPQLP--QAFYPVGHPVDVSFGDLLAA
230 240 250 260 270 280
460 470 480 490 500
pF1KE4 SCTYNTEDRELAT-VGGFGILEEMCVNYVHYYPQTQLELCKSAVDAGFLQKYFHLINRFN
:... : : :: .:: . .::: :. :: ...
XP_016 RCVFTGEGRTEATHIGGTSS-DEMCNLYIMYYMEAKHAVSFMTCTQNVAPDMFRTIPPEA
290 300 310 320 330 340
510 520 530 540 550 560
pF1KE4 NEDVCTCPQASVSQQFTSVPWNSFNRDVLKALYSFAPISMHCNKSSAVRFQGEWNLQPLP
XP_016 NIPIPVKSDMVMMHEHHKETEYKDKIPLLQQPKREEEEVLDQDFHMEEALDWPGVYLLPG
350 360 370 380 390 400
>>XP_016865002 (OMIM: 170270) PREDICTED: peptidyl-glycin (819 aa)
initn: 259 init1: 100 opt: 167 Z-score: 195.9 bits: 46.7 E(85289): 0.00036
Smith-Waterman score: 368; 28.4% identity (54.2% similar) in 306 aa overlap (185-485:47-321)
160 170 180 190 200 210
pF1KE4 VYGILEEPFRSLEAINGSGLQMGLQRVQLLKPNIPEPELPSDACTMEVQAPNIQIPSQET
.: .: . :. ..... :.. :.:
XP_016 SCLAFRSPLSVFKRFKETTRPFSNECLGTTRPVVP---IDSSDFALDIRMPGVT-PKQSD
20 30 40 50 60 70
220 230 240 250 260 270
pF1KE4 TYWCYIKELPKGFSRHHIIKYEPIVTKGNEALVHHMEVFQCAPEMDSVPHFSGP---CDS
::.:. ..: . .: ..: ... :::: .: : ..: .: ::
XP_016 TYFCMSMRIPVD-EEAFVIDFKP---RASMDTVHHMLLFGC-----NMPSSTGSYWFCDE
80 90 100 110 120
280 290 300 310 320 330
pF1KE4 KMKPDRLNYCRHVLAAWALGAKAFYYPEEAGLAFGGPGSSRYLRLEVHYHNPLVIEGRN-
:. : .: ::: .: :. .:. :: .:.:. :.::: . ... :
XP_016 GTCTDKAN----ILYAWARNAPPTRLPKGVGFRVGGETGSKYFVLQVHYGDISAFRDNNK
130 140 150 160 170
340 350 360 370 380 390
pF1KE4 DSSGIRLYYTAKLRRFNAGIMELGLVYTPVMAIPPRETAFILTGYCTDKCTQLALPPSGI
: ::. :. : . . ::.. . : : .:: : . : : : .
XP_016 DCSGVSLHLTRLPQPLIAGMYLMMSVDT---VIPAGEKVVNSDISCHYK----NYP---M
180 190 200 210 220
400 410 420 430 440 450
pF1KE4 HIFASQLHTHLTGRKVVTVLVRDGREWEIVNQDNHYSPHFQEIRMLKKVVSVHPGDVLIT
:.:: ..::: :. : ::.: .: ...... : : . . . :.: ::.: .
XP_016 HVFAYRVHTHHLGKVVSGYRVRNG-QWTLIGRQSPQLP--QAFYPVGHPVDVSFGDLLAA
230 240 250 260 270 280
460 470 480 490 500
pF1KE4 SCTYNTEDRELAT-VGGFGILEEMCVNYVHYYPQTQLELCKSAVDAGFLQKYFHLINRFN
:... : : :: .:: . .::: :. :: ...
XP_016 RCVFTGEGRTEATHIGGTSS-DEMCNLYIMYYMEAKHAVSFMTCTQNVAPDMFRTIPPEA
290 300 310 320 330 340
510 520 530 540 550 560
pF1KE4 NEDVCTCPQASVSQQFTSVPWNSFNRDVLKALYSFAPISMHCNKSSAVRFQGEWNLQPLP
XP_016 NIPIPVKSDMVMMHEHHKETEYKDKIPLLQQPKREEEEVLDQGDFYSLLSKLLGEREDVV
350 360 370 380 390 400
>>XP_016865001 (OMIM: 170270) PREDICTED: peptidyl-glycin (837 aa)
initn: 259 init1: 100 opt: 167 Z-score: 195.7 bits: 46.7 E(85289): 0.00036
Smith-Waterman score: 368; 28.4% identity (54.2% similar) in 306 aa overlap (185-485:47-321)
160 170 180 190 200 210
pF1KE4 VYGILEEPFRSLEAINGSGLQMGLQRVQLLKPNIPEPELPSDACTMEVQAPNIQIPSQET
.: .: . :. ..... :.. :.:
XP_016 SCLAFRSPLSVFKRFKETTRPFSNECLGTTRPVVP---IDSSDFALDIRMPGVT-PKQSD
20 30 40 50 60 70
220 230 240 250 260 270
pF1KE4 TYWCYIKELPKGFSRHHIIKYEPIVTKGNEALVHHMEVFQCAPEMDSVPHFSGP---CDS
::.:. ..: . .: ..: ... :::: .: : ..: .: ::
XP_016 TYFCMSMRIPVD-EEAFVIDFKP---RASMDTVHHMLLFGC-----NMPSSTGSYWFCDE
80 90 100 110 120
280 290 300 310 320 330
pF1KE4 KMKPDRLNYCRHVLAAWALGAKAFYYPEEAGLAFGGPGSSRYLRLEVHYHNPLVIEGRN-
:. : .: ::: .: :. .:. :: .:.:. :.::: . ... :
XP_016 GTCTDKAN----ILYAWARNAPPTRLPKGVGFRVGGETGSKYFVLQVHYGDISAFRDNNK
130 140 150 160 170
340 350 360 370 380 390
pF1KE4 DSSGIRLYYTAKLRRFNAGIMELGLVYTPVMAIPPRETAFILTGYCTDKCTQLALPPSGI
: ::. :. : . . ::.. . : : .:: : . : : : .
XP_016 DCSGVSLHLTRLPQPLIAGMYLMMSVDT---VIPAGEKVVNSDISCHYK----NYP---M
180 190 200 210 220
400 410 420 430 440 450
pF1KE4 HIFASQLHTHLTGRKVVTVLVRDGREWEIVNQDNHYSPHFQEIRMLKKVVSVHPGDVLIT
:.:: ..::: :. : ::.: .: ...... : : . . . :.: ::.: .
XP_016 HVFAYRVHTHHLGKVVSGYRVRNG-QWTLIGRQSPQLP--QAFYPVGHPVDVSFGDLLAA
230 240 250 260 270 280
460 470 480 490 500
pF1KE4 SCTYNTEDRELAT-VGGFGILEEMCVNYVHYYPQTQLELCKSAVDAGFLQKYFHLINRFN
:... : : :: .:: . .::: :. :: ...
XP_016 RCVFTGEGRTEATHIGGTSS-DEMCNLYIMYYMEAKHAVSFMTCTQNVAPDMFRTIPPEA
290 300 310 320 330 340
510 520 530 540 550 560
pF1KE4 NEDVCTCPQASVSQQFTSVPWNSFNRDVLKALYSFAPISMHCNKSSAVRFQGEWNLQPLP
XP_016 NIPIPVKSDMVMMHEHHKETEYKDKIPLLQQPKREEEEVLDQGDFYSLLSKLLGEREDVV
350 360 370 380 390 400
>>XP_016865000 (OMIM: 170270) PREDICTED: peptidyl-glycin (838 aa)
initn: 259 init1: 100 opt: 167 Z-score: 195.7 bits: 46.7 E(85289): 0.00037
Smith-Waterman score: 368; 28.4% identity (54.2% similar) in 306 aa overlap (185-485:47-321)
160 170 180 190 200 210
pF1KE4 VYGILEEPFRSLEAINGSGLQMGLQRVQLLKPNIPEPELPSDACTMEVQAPNIQIPSQET
.: .: . :. ..... :.. :.:
XP_016 SCLAFRSPLSVFKRFKETTRPFSNECLGTTRPVVP---IDSSDFALDIRMPGVT-PKQSD
20 30 40 50 60 70
220 230 240 250 260 270
pF1KE4 TYWCYIKELPKGFSRHHIIKYEPIVTKGNEALVHHMEVFQCAPEMDSVPHFSGP---CDS
::.:. ..: . .: ..: ... :::: .: : ..: .: ::
XP_016 TYFCMSMRIPVD-EEAFVIDFKP---RASMDTVHHMLLFGC-----NMPSSTGSYWFCDE
80 90 100 110 120
280 290 300 310 320 330
pF1KE4 KMKPDRLNYCRHVLAAWALGAKAFYYPEEAGLAFGGPGSSRYLRLEVHYHNPLVIEGRN-
:. : .: ::: .: :. .:. :: .:.:. :.::: . ... :
XP_016 GTCTDKAN----ILYAWARNAPPTRLPKGVGFRVGGETGSKYFVLQVHYGDISAFRDNNK
130 140 150 160 170
340 350 360 370 380 390
pF1KE4 DSSGIRLYYTAKLRRFNAGIMELGLVYTPVMAIPPRETAFILTGYCTDKCTQLALPPSGI
: ::. :. : . . ::.. . : : .:: : . : : : .
XP_016 DCSGVSLHLTRLPQPLIAGMYLMMSVDT---VIPAGEKVVNSDISCHYK----NYP---M
180 190 200 210 220
400 410 420 430 440 450
pF1KE4 HIFASQLHTHLTGRKVVTVLVRDGREWEIVNQDNHYSPHFQEIRMLKKVVSVHPGDVLIT
:.:: ..::: :. : ::.: .: ...... : : . . . :.: ::.: .
XP_016 HVFAYRVHTHHLGKVVSGYRVRNG-QWTLIGRQSPQLP--QAFYPVGHPVDVSFGDLLAA
230 240 250 260 270 280
460 470 480 490 500
pF1KE4 SCTYNTEDRELAT-VGGFGILEEMCVNYVHYYPQTQLELCKSAVDAGFLQKYFHLINRFN
:... : : :: .:: . .::: :. :: ...
XP_016 RCVFTGEGRTEATHIGGTSS-DEMCNLYIMYYMEAKHAVSFMTCTQNVAPDMFRTIPPEA
290 300 310 320 330 340
510 520 530 540 550 560
pF1KE4 NEDVCTCPQASVSQQFTSVPWNSFNRDVLKALYSFAPISMHCNKSSAVRFQGEWNLQPLP
XP_016 NIPIPVKSDMVMMHEHHKETEYKDKIPLLQQPKREEEEVLDQGDFYSLLSKLLGEREDVV
350 360 370 380 390 400
603 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 00:09:38 2016 done: Sun Nov 6 00:09:39 2016
Total Scan time: 9.270 Total Display time: 0.060
Function used was FASTA [36.3.4 Apr, 2011]