Result of FASTA (ccds) for
pFN21AE4528
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE4528, 577 aa
1>>>pF1KE4528 577 - 577 aa - 577 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.0258+/-0.000936; mu= 20.0156+/- 0.056
mean_var=60.9549+/-12.843, 0's: 0 Z-trim(104.9): 22 B-trim: 0 in 0/47
Lambda= 0.164274
statistics sampled from 8117 (8125) to 8117 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.615), E-opt: 0.2 (0.25), width: 16
Scan time: 3.230
The best scores are: opt bits E(32554)
CCDS74436.1 HAS1 gene_id:3036|Hs108|chr19 ( 577) 3932 940.7 0
CCDS12838.1 HAS1 gene_id:3036|Hs108|chr19 ( 578) 3920 937.9 0
CCDS10871.1 HAS3 gene_id:3038|Hs108|chr16 ( 553) 1677 406.3 5.1e-113
CCDS6335.1 HAS2 gene_id:3037|Hs108|chr8 ( 552) 1671 404.9 1.4e-112
CCDS10870.1 HAS3 gene_id:3038|Hs108|chr16 ( 281) 357 93.3 4.4e-19
>>CCDS74436.1 HAS1 gene_id:3036|Hs108|chr19 (577 aa)
initn: 3932 init1: 3932 opt: 3932 Z-score: 5030.5 bits: 940.7 E(32554): 0
Smith-Waterman score: 3932; 99.7% identity (99.8% similar) in 577 aa overlap (1-577:1-577)
10 20 30 40 50 60
pF1KE4 MRQDAPKPTPAARRCSGLARRVLTIAFALLILGLMTWAYAAGVPLASDRYGLLAFGLYGA
:::::::::::: :::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 MRQDAPKPTPAACRCSGLARRVLTIAFALLILGLMTWAYAAGVPLASDRYGLLAFGLYGA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 FLSAHLVAQSLFAYLEHRRVAAAARGPLDAATARSVALTISAYQEDPAYLRQCLASARAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 FLSAHLVAQSLFAYLEHRRVAAAARGPLDAATARSVALTISAYQEDPAYLRQCLASARAL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 LYPRARLRVLMVVDGNRAEDLYMVDMFREVFADEDPATYVWDGNYHQPWEPAAAGAVGAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 LYPRARLRVLMVVDGNRAEDLYMVDMFREVFADEDPATYVWDGNYHQPWEPAAAGAVGAG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 AYREVEAEDPGRLAVEALVRTRRCVCVAQRWGGKREVMYTAFKALGDSMDYVQVCDSDTR
::::::::::::::::::::::::::::::::::::::::::::::::.:::::::::::
CCDS74 AYREVEAEDPGRLAVEALVRTRRCVCVAQRWGGKREVMYTAFKALGDSVDYVQVCDSDTR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 LDPMALLELVRVLDEDPRVGAVGGDVRILNPLDSWVSFLSSLRYWVAFNVERACQSYFHC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 LDPMALLELVRVLDEDPRVGAVGGDVRILNPLDSWVSFLSSLRYWVAFNVERACQSYFHC
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 VSCISGPLGLYRNNLLQQFLEAWYNQKFLGTHCTFGDDRHLTNRMLSMGYATKYTSRSRC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 VSCISGPLGLYRNNLLQQFLEAWYNQKFLGTHCTFGDDRHLTNRMLSMGYATKYTSRSRC
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 YSETPSSFLRWLSQQTRWSKSYFREWLYNALWWHRHHAWMTYEAVVSGLFPFFVAATVLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 YSETPSSFLRWLSQQTRWSKSYFREWLYNALWWHRHHAWMTYEAVVSGLFPFFVAATVLR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE4 LFYAGRPWALLWVLLCVQGVALAKAAFAAWLRGCLRMVLLSLYAPLYMCGLLPAKFLALV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 LFYAGRPWALLWVLLCVQGVALAKAAFAAWLRGCLRMVLLSLYAPLYMCGLLPAKFLALV
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE4 TMNQSGWGTSGRRKLAANYVPLLPLALWALLLLGGLVRSVAHEARADWSGPSRAAEAYHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 TMNQSGWGTSGRRKLAANYVPLLPLALWALLLLGGLVRSVAHEARADWSGPSRAAEAYHL
490 500 510 520 530 540
550 560 570
pF1KE4 AAGAGAYVGYWVAMLTLYWVGVRRLCRRRTGGYRVQV
:::::::::::::::::::::::::::::::::::::
CCDS74 AAGAGAYVGYWVAMLTLYWVGVRRLCRRRTGGYRVQV
550 560 570
>>CCDS12838.1 HAS1 gene_id:3036|Hs108|chr19 (578 aa)
initn: 3919 init1: 3919 opt: 3920 Z-score: 5015.1 bits: 937.9 E(32554): 0
Smith-Waterman score: 3920; 99.5% identity (99.7% similar) in 578 aa overlap (1-577:1-578)
10 20 30 40 50
pF1KE4 MRQ-DAPKPTPAARRCSGLARRVLTIAFALLILGLMTWAYAAGVPLASDRYGLLAFGLYG
::: ::::::::: ::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 MRQQDAPKPTPAACRCSGLARRVLTIAFALLILGLMTWAYAAGVPLASDRYGLLAFGLYG
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE4 AFLSAHLVAQSLFAYLEHRRVAAAARGPLDAATARSVALTISAYQEDPAYLRQCLASARA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 AFLSAHLVAQSLFAYLEHRRVAAAARGPLDAATARSVALTISAYQEDPAYLRQCLASARA
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE4 LLYPRARLRVLMVVDGNRAEDLYMVDMFREVFADEDPATYVWDGNYHQPWEPAAAGAVGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 LLYPRARLRVLMVVDGNRAEDLYMVDMFREVFADEDPATYVWDGNYHQPWEPAAAGAVGA
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE4 GAYREVEAEDPGRLAVEALVRTRRCVCVAQRWGGKREVMYTAFKALGDSMDYVQVCDSDT
:::::::::::::::::::::::::::::::::::::::::::::::::.::::::::::
CCDS12 GAYREVEAEDPGRLAVEALVRTRRCVCVAQRWGGKREVMYTAFKALGDSVDYVQVCDSDT
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE4 RLDPMALLELVRVLDEDPRVGAVGGDVRILNPLDSWVSFLSSLRYWVAFNVERACQSYFH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 RLDPMALLELVRVLDEDPRVGAVGGDVRILNPLDSWVSFLSSLRYWVAFNVERACQSYFH
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE4 CVSCISGPLGLYRNNLLQQFLEAWYNQKFLGTHCTFGDDRHLTNRMLSMGYATKYTSRSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 CVSCISGPLGLYRNNLLQQFLEAWYNQKFLGTHCTFGDDRHLTNRMLSMGYATKYTSRSR
310 320 330 340 350 360
360 370 380 390 400 410
pF1KE4 CYSETPSSFLRWLSQQTRWSKSYFREWLYNALWWHRHHAWMTYEAVVSGLFPFFVAATVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 CYSETPSSFLRWLSQQTRWSKSYFREWLYNALWWHRHHAWMTYEAVVSGLFPFFVAATVL
370 380 390 400 410 420
420 430 440 450 460 470
pF1KE4 RLFYAGRPWALLWVLLCVQGVALAKAAFAAWLRGCLRMVLLSLYAPLYMCGLLPAKFLAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 RLFYAGRPWALLWVLLCVQGVALAKAAFAAWLRGCLRMVLLSLYAPLYMCGLLPAKFLAL
430 440 450 460 470 480
480 490 500 510 520 530
pF1KE4 VTMNQSGWGTSGRRKLAANYVPLLPLALWALLLLGGLVRSVAHEARADWSGPSRAAEAYH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 VTMNQSGWGTSGRRKLAANYVPLLPLALWALLLLGGLVRSVAHEARADWSGPSRAAEAYH
490 500 510 520 530 540
540 550 560 570
pF1KE4 LAAGAGAYVGYWVAMLTLYWVGVRRLCRRRTGGYRVQV
::::::::::::::::::::::::::::::::::::::
CCDS12 LAAGAGAYVGYWVAMLTLYWVGVRRLCRRRTGGYRVQV
550 560 570
>>CCDS10871.1 HAS3 gene_id:3038|Hs108|chr16 (553 aa)
initn: 2044 init1: 1619 opt: 1677 Z-score: 2142.5 bits: 406.3 E(32554): 5.1e-113
Smith-Waterman score: 2081; 55.6% identity (77.7% similar) in 556 aa overlap (20-573:10-546)
10 20 30 40 50 60
pF1KE4 MRQDAPKPTPAARRCSGLARRVLTIAFALLILGLMTWAYAAGVPLASDRYGLLAFGLYGA
: : : ::: .:: . ::..: . . :.::::::
CCDS10 MPVQLTTALRVVGTSLFALAVLGGILAAYVTGYQFIHTEKHYLSFGLYGA
10 20 30 40 50
70 80 90 100 110
pF1KE4 FLSAHLVAQSLFAYLEHRRVAAAARG-PLDAATARSVALTISAYQEDPAYLRQCLASARA
.:. ::. :::::.:::::. :... : . :::: :.:::::: :::.:: ::.
CCDS10 ILGLHLLIQSLFAFLEHRRMRRAGQALKLPSPRRGSVALCIAAYQEDPDYLRKCLRSAQR
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE4 LLYPRARLRVLMVVDGNRAEDLYMVDMFREVFADEDPATY-VWDGNYHQPWEPAAAGAVG
. .: :.:.::::::: :: ::.:.:.::.. . : . :: .:.:. : . ...
CCDS10 ISFPD--LKVVMVVDGNRQEDAYMLDIFHEVLGGTEQAGFFVWRSNFHEAGEGETEASLQ
120 130 140 150 160
180 190 200 210 220 230
pF1KE4 AGAYREVEAEDPGRLAVEALVRTRRCVCVAQRWGGKREVMYTAFKALGDSMDYVQVCDSD
: : :. .::. :. :.::::::::::::::::::.::.::::::
CCDS10 EGMDR-----------VRDVVRASTFSCIMQKWGGKREVMYTAFKALGDSVDYIQVCDSD
170 180 190 200 210
240 250 260 270 280 290
pF1KE4 TRLDPMALLELVRVLDEDPRVGAVGGDVRILNPLDSWVSFLSSLRYWVAFNVERACQSYF
: ::: .:..:::.:::.::.:::::.::: :::.:::::.:::.::::::::::::
CCDS10 TVLDPACTIEMLRVLEEDPQVGGVGGDVQILNKYDSWISFLSSVRYWMAFNVERACQSYF
220 230 240 250 260 270
300 310 320 330 340 350
pF1KE4 HCVSCISGPLGLYRNNLLQQFLEAWYNQKFLGTHCTFGDDRHLTNRMLSMGYATKYTSRS
::.:::::::.:::.::::::: ::.:::::..:.::::::::::.::.:: ::::.::
CCDS10 GCVQCISGPLGMYRNSLLQQFLEDWYHQKFLGSKCSFGDDRHLTNRVLSLGYRTKYTARS
280 290 300 310 320 330
360 370 380 390 400 410
pF1KE4 RCYSETPSSFLRWLSQQTRWSKSYFREWLYNALWWHRHHAWMTYEAVVSGLFPFFVAATV
.: .:::...::::.::::::::::::::::.::.:.:: :::::.::.:.::::. :::
CCDS10 KCLTETPTKYLRWLNQQTRWSKSYFREWLYNSLWFHKHHLWMTYESVVTGFFPFFLIATV
340 350 360 370 380 390
420 430 440 450 460 470
pF1KE4 LRLFYAGRPWALLWVLLCVQGVALAKAAFAAWLRGCLRMVLLSLYAPLYMCGLLPAKFLA
..::: :: : .: :: :: :.. ::..: .::: .:...:::. ::: .:::::..:
CCDS10 IQLFYRGRIWNILLFLLTVQLVGIIKATYACFLRGNAEMIFMSLYSLLYMSSLLPAKIFA
400 410 420 430 440 450
480 490 500 510 520 530
pF1KE4 LVTMNQSGWGTSGRRKLAANYVPLLPLALWALLLLGGLVRSVAHEARADWSGPSRAAEAY
..:.:.::::::::. ...:.. :.:...:. .:::::. .. . : . .. :
CCDS10 IATINKSGWGTSGRKTIVVNFIGLIPVSIWVAVLLGGLAYTAYCQ---DLFSETELA---
460 470 480 490 500 510
540 550 560 570
pF1KE4 HLAAGAGAYVGYWVAMLTLYWVGVRRLCRRRTGGYRVQV
:..:: : ::::.: :: . . : : .. :
CCDS10 FLVSGAILYGCYWVALLMLYLAIIARRCGKKPEQYSLAFAEV
520 530 540 550
>>CCDS6335.1 HAS2 gene_id:3037|Hs108|chr8 (552 aa)
initn: 2058 init1: 1603 opt: 1671 Z-score: 2134.8 bits: 404.9 E(32554): 1.4e-112
Smith-Waterman score: 2081; 53.9% identity (78.5% similar) in 553 aa overlap (20-571:11-543)
10 20 30 40 50
pF1KE4 MRQDAPKPTPAARRCSGLARRVLTIAFALLILGLMTWAYAAGVP-LASDRYGLLAFGLYG
: . : :.. .: .: :: .: . .: : ..:::::
CCDS63 MHCERFLCILRIIGTTLFGVSLLLGITAAYIVGYQFIQTDNY-YFSFGLYG
10 20 30 40 50
60 70 80 90 100 110
pF1KE4 AFLSAHLVAQSLFAYLEHRRVAAAARGPLDAATARSVALTISAYQEDPAYLRQCLASARA
:::..::. :::::.::::.. . . :. ..::: :.:::::: :::.:: :..
CCDS63 AFLASHLIIQSLFAFLEHRKMKKSLETPI--KLNKTVALCIAAYQEDPDYLRKCLQSVKR
60 70 80 90 100
120 130 140 150 160 170
pF1KE4 LLYPRARLRVLMVVDGNRAEDLYMVDMFREVFADEDPATYVWDGNYHQPWEPAAAGAVGA
: :: ..:.::.::: .::::.:.: ::.. . :::.: .:.:. :
CCDS63 LTYPG--IKVVMVIDGNSEDDLYMMDIFSEVMGRDKSATYIWKNNFHEK---------GP
110 120 130 140 150
180 190 200 210 220 230
pF1KE4 GAYREVEAEDPGRLAVEALVRTRRCVCVAQRWGGKREVMYTAFKALGDSMDYVQVCDSDT
: : . :. . : :: . . .:. :.::::::::::::.::: :.::::::::::
CCDS63 GETDESHKESSQH--VTQLVLSNKSICIMQKWGGKREVMYTAFRALGRSVDYVQVCDSDT
160 170 180 190 200 210
240 250 260 270 280 290
pF1KE4 RLDPMALLELVRVLDEDPRVGAVGGDVRILNPLDSWVSFLSSLRYWVAFNVERACQSYFH
::: . .:.:.::.::: ::.:::::.::: :::.:::::.:::.:::.::::::::
CCDS63 MLDPASSVEMVKVLEEDPMVGGVGGDVQILNKYDSWISFLSSVRYWMAFNIERACQSYFG
220 230 240 250 260 270
300 310 320 330 340 350
pF1KE4 CVSCISGPLGLYRNNLLQQFLEAWYNQKFLGTHCTFGDDRHLTNRMLSMGYATKYTSRSR
::.:::::::.:::.::..:.: ::::.:.:..:.::::::::::.::.:::::::.::.
CCDS63 CVQCISGPLGMYRNSLLHEFVEDWYNQEFMGNQCSFGDDRHLTNRVLSLGYATKYTARSK
280 290 300 310 320 330
360 370 380 390 400 410
pF1KE4 CYSETPSSFLRWLSQQTRWSKSYFREWLYNALWWHRHHAWMTYEAVVSGLFPFFVAATVL
: .::: .::::.:::::::::::::::::.:.:.:: ::::::...:.::::. :::.
CCDS63 CLTETPIEYLRWLNQQTRWSKSYFREWLYNAMWFHKHHLWMTYEAIITGFFPFFLIATVI
340 350 360 370 380 390
420 430 440 450 460 470
pF1KE4 RLFYAGRPWALLWVLLCVQGVALAKAAFAAWLRGCLRMVLLSLYAPLYMCGLLPAKFLAL
.::: :. : .: :: :: :.: :..::. ::: . ::..:::. ::: .:::::..:.
CCDS63 QLFYRGKIWNILLFLLTVQLVGLIKSSFASCLRGNIVMVFMSLYSVLYMSSLLPAKMFAI
400 410 420 430 440 450
480 490 500 510 520 530
pF1KE4 VTMNQSGWGTSGRRKLAANYVPLLPLALWALLLLGGLVRSVAHEARADWSGPSRAAEAYH
.:.:..:::::::. ...:.. :.:...: .::::.. .. .:.. .: ....
CCDS63 ATINKAGWGTSGRKTIVVNFIGLIPVSVWFTILLGGVIFTIYKESKRPFSESKQTV----
460 470 480 490 500 510
540 550 560 570
pF1KE4 LAAGAGAYVGYWVAMLTLYWVGVRRLCRRRTGGYRVQV
: .:. :. ::: .:::: : . . ::. :
CCDS63 LIVGTLLYACYWVMLLTLYVVLINKCGRRKKGQQYDMVLDV
520 530 540 550
>>CCDS10870.1 HAS3 gene_id:3038|Hs108|chr16 (281 aa)
initn: 727 init1: 355 opt: 357 Z-score: 456.2 bits: 93.3 E(32554): 4.4e-19
Smith-Waterman score: 761; 50.4% identity (70.8% similar) in 250 aa overlap (20-267:10-246)
10 20 30 40 50 60
pF1KE4 MRQDAPKPTPAARRCSGLARRVLTIAFALLILGLMTWAYAAGVPLASDRYGLLAFGLYGA
: : : ::: .:: . ::..: . . :.::::::
CCDS10 MPVQLTTALRVVGTSLFALAVLGGILAAYVTGYQFIHTEKHYLSFGLYGA
10 20 30 40 50
70 80 90 100 110
pF1KE4 FLSAHLVAQSLFAYLEHRRVAAAARG-PLDAATARSVALTISAYQEDPAYLRQCLASARA
.:. ::. :::::.:::::. :... : . :::: :.:::::: :::.:: ::.
CCDS10 ILGLHLLIQSLFAFLEHRRMRRAGQALKLPSPRRGSVALCIAAYQEDPDYLRKCLRSAQR
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE4 LLYPRARLRVLMVVDGNRAEDLYMVDMFREVFADEDPATY-VWDGNYHQPWEPAAAGAVG
. .: :.:.::::::: :: ::.:.:.::.. . : . :: .:.:. : . ...
CCDS10 ISFP--DLKVVMVVDGNRQEDAYMLDIFHEVLGGTEQAGFFVWRSNFHEAGEGETEASLQ
120 130 140 150 160
180 190 200 210 220 230
pF1KE4 AGAYREVEAEDPGRLAVEALVRTRRCVCVAQRWGGKREVMYTAFKALGDSMDYVQVCDSD
: : :. .::. :. :.::::::::::::::::::.::.::::::
CCDS10 EGMDR-----------VRDVVRASTFSCIMQKWGGKREVMYTAFKALGDSVDYIQVCDSD
170 180 190 200 210
240 250 260 270 280 290
pF1KE4 TRLDPMALLELVRVLDEDPRVGAVGGDVRILNPLDSWVSFLSSLRYWVAFNVERACQSYF
: ::: .:..:::.:::.::.:::::.
CCDS10 TVLDPACTIEMLRVLEEDPQVGGVGGDVQPPGKGMAVEDDQVQAAQVRATEAWSVHQRHV
220 230 240 250 260 270
577 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 00:14:17 2016 done: Sun Nov 6 00:14:18 2016
Total Scan time: 3.230 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]