Result of FASTA (ccds) for
pFN21AE4494
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE4494, 515 aa
1>>>pF1KE4494 515 - 515 aa - 515 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.8165+/-0.00103; mu= 14.5159+/- 0.062
mean_var=58.6720+/-11.928, 0's: 0 Z-trim(102.4): 24 B-trim: 0 in 0/49
Lambda= 0.167440
statistics sampled from 6923 (6928) to 6923 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.583), E-opt: 0.2 (0.213), width: 16
Scan time: 3.000
The best scores are: opt bits E(32554)
CCDS44023.1 G6PD gene_id:2539|Hs108|chrX ( 515) 3486 850.9 0
CCDS14756.2 G6PD gene_id:2539|Hs108|chrX ( 545) 3486 850.9 0
CCDS101.1 H6PD gene_id:9563|Hs108|chr1 ( 791) 669 170.4 6.6e-42
CCDS72697.1 H6PD gene_id:9563|Hs108|chr1 ( 802) 669 170.4 6.7e-42
>>CCDS44023.1 G6PD gene_id:2539|Hs108|chrX (515 aa)
initn: 3486 init1: 3486 opt: 3486 Z-score: 4546.8 bits: 850.9 E(32554): 0
Smith-Waterman score: 3486; 100.0% identity (100.0% similar) in 515 aa overlap (1-515:1-515)
10 20 30 40 50 60
pF1KE4 MAEQVALSRTQVCGILREELFQGDAFHQSDTHIFIIMGASGDLAKKKIYPTIWWLFRDGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 MAEQVALSRTQVCGILREELFQGDAFHQSDTHIFIIMGASGDLAKKKIYPTIWWLFRDGL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 LPENTFIVGYARSRLTVADIRKQSEPFFKATPEEKLKLEDFFARNSYVAGQYDDAASYQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 LPENTFIVGYARSRLTVADIRKQSEPFFKATPEEKLKLEDFFARNSYVAGQYDDAASYQR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 LNSHMNALHLGSQANRLFYLALPPTVYEAVTKNIHESCMSQIGWNRIIVEKPFGRDLQSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 LNSHMNALHLGSQANRLFYLALPPTVYEAVTKNIHESCMSQIGWNRIIVEKPFGRDLQSS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 DRLSNHISSLFREDQIYRIDHYLGKEMVQNLMVLRFANRIFGPIWNRDNIACVILTFKEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 DRLSNHISSLFREDQIYRIDHYLGKEMVQNLMVLRFANRIFGPIWNRDNIACVILTFKEP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 FGTEGRGGYFDEFGIIRDVMQNHLLQMLCLVAMEKPASTNSDDVRDEKVKVLKCISEVQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 FGTEGRGGYFDEFGIIRDVMQNHLLQMLCLVAMEKPASTNSDDVRDEKVKVLKCISEVQA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 NNVVLGQYVGNPDGEGEATKGYLDDPTVPRGSTTATFAAVVLYVENERWDGVPFILRCGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 NNVVLGQYVGNPDGEGEATKGYLDDPTVPRGSTTATFAAVVLYVENERWDGVPFILRCGK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 ALNERKAEVRLQFHDVAGDIFHQQCKRNELVIRVQPNEAVYTKMMTKKPGMFFNPEESEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 ALNERKAEVRLQFHDVAGDIFHQQCKRNELVIRVQPNEAVYTKMMTKKPGMFFNPEESEL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE4 DLTYGNRYKNVKLPDAYERLILDVFCGSQMHFVRSDELREAWRIFTPLLHQIELEKPKPI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 DLTYGNRYKNVKLPDAYERLILDVFCGSQMHFVRSDELREAWRIFTPLLHQIELEKPKPI
430 440 450 460 470 480
490 500 510
pF1KE4 PYIYGSRGPTEADELMKRVGFQYEGTYKWVNPHKL
:::::::::::::::::::::::::::::::::::
CCDS44 PYIYGSRGPTEADELMKRVGFQYEGTYKWVNPHKL
490 500 510
>>CCDS14756.2 G6PD gene_id:2539|Hs108|chrX (545 aa)
initn: 3486 init1: 3486 opt: 3486 Z-score: 4546.3 bits: 850.9 E(32554): 0
Smith-Waterman score: 3486; 100.0% identity (100.0% similar) in 515 aa overlap (1-515:31-545)
10 20 30
pF1KE4 MAEQVALSRTQVCGILREELFQGDAFHQSD
::::::::::::::::::::::::::::::
CCDS14 MGRRGSAPGNGRTLRGCERGGRRRRSADSVMAEQVALSRTQVCGILREELFQGDAFHQSD
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE4 THIFIIMGASGDLAKKKIYPTIWWLFRDGLLPENTFIVGYARSRLTVADIRKQSEPFFKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 THIFIIMGASGDLAKKKIYPTIWWLFRDGLLPENTFIVGYARSRLTVADIRKQSEPFFKA
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE4 TPEEKLKLEDFFARNSYVAGQYDDAASYQRLNSHMNALHLGSQANRLFYLALPPTVYEAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 TPEEKLKLEDFFARNSYVAGQYDDAASYQRLNSHMNALHLGSQANRLFYLALPPTVYEAV
130 140 150 160 170 180
160 170 180 190 200 210
pF1KE4 TKNIHESCMSQIGWNRIIVEKPFGRDLQSSDRLSNHISSLFREDQIYRIDHYLGKEMVQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 TKNIHESCMSQIGWNRIIVEKPFGRDLQSSDRLSNHISSLFREDQIYRIDHYLGKEMVQN
190 200 210 220 230 240
220 230 240 250 260 270
pF1KE4 LMVLRFANRIFGPIWNRDNIACVILTFKEPFGTEGRGGYFDEFGIIRDVMQNHLLQMLCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 LMVLRFANRIFGPIWNRDNIACVILTFKEPFGTEGRGGYFDEFGIIRDVMQNHLLQMLCL
250 260 270 280 290 300
280 290 300 310 320 330
pF1KE4 VAMEKPASTNSDDVRDEKVKVLKCISEVQANNVVLGQYVGNPDGEGEATKGYLDDPTVPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 VAMEKPASTNSDDVRDEKVKVLKCISEVQANNVVLGQYVGNPDGEGEATKGYLDDPTVPR
310 320 330 340 350 360
340 350 360 370 380 390
pF1KE4 GSTTATFAAVVLYVENERWDGVPFILRCGKALNERKAEVRLQFHDVAGDIFHQQCKRNEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 GSTTATFAAVVLYVENERWDGVPFILRCGKALNERKAEVRLQFHDVAGDIFHQQCKRNEL
370 380 390 400 410 420
400 410 420 430 440 450
pF1KE4 VIRVQPNEAVYTKMMTKKPGMFFNPEESELDLTYGNRYKNVKLPDAYERLILDVFCGSQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 VIRVQPNEAVYTKMMTKKPGMFFNPEESELDLTYGNRYKNVKLPDAYERLILDVFCGSQM
430 440 450 460 470 480
460 470 480 490 500 510
pF1KE4 HFVRSDELREAWRIFTPLLHQIELEKPKPIPYIYGSRGPTEADELMKRVGFQYEGTYKWV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 HFVRSDELREAWRIFTPLLHQIELEKPKPIPYIYGSRGPTEADELMKRVGFQYEGTYKWV
490 500 510 520 530 540
pF1KE4 NPHKL
:::::
CCDS14 NPHKL
>>CCDS101.1 H6PD gene_id:9563|Hs108|chr1 (791 aa)
initn: 650 init1: 193 opt: 669 Z-score: 865.8 bits: 170.4 E(32554): 6.6e-42
Smith-Waterman score: 785; 32.6% identity (62.4% similar) in 503 aa overlap (14-481:15-502)
10 20 30 40 50
pF1KE4 MAEQVALSRTQVCGILREELFQGDAFHQSDTHIFIIMGASGDLAKKKIYPTIWWLFRDG
: :. . .:: : : .:..::.:::::: .. .. :. :
CCDS10 MWNMLIVAMCLALLGCLQAQELQG---HVS----IILLGATGDLAKKYLWQGLFQLYLDE
10 20 30 40 50
60 70 80 90 100 110
pF1KE4 LLPENTFIV-GYARS------RLTVADIRKQSEPFFKATPEEKLKLEDFFARNSYVAGQY
..: : : . .: . ... : : .: . . .: : . : :
CCDS10 AGRGHSFSFHGAALTAPKQGQELMAKALESLSCPK-DMAPSHCAEHKDQFLQLSQYR-QL
60 70 80 90 100 110
120 130 140 150 160
pF1KE4 DDAASYQRLNSHMNAL--HLG-SQANRLFYLALPPTVYEAVTKNIHESCMSQIG-WNRII
: .:: ::. ..: : : .:.:.::...:: .:: ...::. :: : : :..
CCDS10 KTAEDYQALNKDIEAQLQHAGLREAGRIFYFSVPPFAYEDIARNINSSCRPGPGAWLRVV
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE4 VEKPFGRDLQSSDRLSNHISSLFREDQIYRIDHYLGKEMVQNLMVLRFANR-IFGPIWNR
.:::::.: :...:.......:.:...::.::::::. : ... .: :: . .:::
CCDS10 LEKPFGHDHFSAQQLATELGTFFQEEEMYRVDHYLGKQAVAQILPFRDQNRKALDGLWNR
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE4 DNIACVILTFKEPFGTEGRGGYFDEFGIIRDVMQNHLLQMLCLVAMEKPASTNSDD-VRD
.. : . .:: .::: ....:.:.::::.:::: ..: ::::: : ...: . :
CCDS10 HHVERVEIIMKETVDAEGRTSFYEEYGVIRDVLQNHLTEVLTLVAMELPHNVSSAEAVLR
240 250 260 270 280 290
290 300 310 320 330 340
pF1KE4 EKVKVLKCISEVQANNVVLGQYVGNPDGEGEATKGYLDDPTVPRGSTTATFAAVVLYVEN
.:..:.. . .: ...:.::: .. .: .. :. : . : : :::::.....:
CCDS10 HKLQVFQALRGLQRGSAVVGQY----QSYSEQVRRELQKPDSFH-SLTPTFAAVLVHIDN
300 310 320 330 340
350 360 370 380 390
pF1KE4 ERWDGVPFILRCGKALNERKAEVRLQFHDVAGDI--------FHQQCKRNELVIRVQPNE
::.:::::: ::::.:: . .:. :.. : . ..:: .::... ..
CCDS10 LRWEGVPFILMSGKALDERVGYARILFKNQACCVQSEKHWAAAQSQCLPRQLVFHIGHGD
350 360 370 380 390 400
400 410 420 430 440
pF1KE4 ----AVYTKMMTKKPGMFFNPEESE----LDLTYGN------RYKNVKLPDAYERLILDV
:: .. .:.. . .: : : : .:. :. :. ::. :. .
CCDS10 LGSPAVLVSRNLFRPSLPSSWKEMEGPPGLRL-FGSPLSDYYAYSPVRERDAHSVLLSHI
410 420 430 440 450 460
450 460 470 480 490 500
pF1KE4 FCGSQMHFVRSDELREAWRIFTPLLHQIELEKPKPIPYIYGSRGPTEADELMKRVGFQYE
: : . :. ...: .: ..::::... . :. :
CCDS10 FHGRKNFFITTENLLASWNFWTPLLESLAHKAPRLYPGGAENGRLLDFEFSSGRLFFSQQ
470 480 490 500 510 520
510
pF1KE4 GTYKWVNPHKL
CCDS10 QPEQLVPGPGPAPMPSDFQVLRAKYRESPLVSAWSEELISKLANDIEATAVRAVRRFGQF
530 540 550 560 570 580
>>CCDS72697.1 H6PD gene_id:9563|Hs108|chr1 (802 aa)
initn: 650 init1: 193 opt: 669 Z-score: 865.7 bits: 170.4 E(32554): 6.7e-42
Smith-Waterman score: 785; 32.6% identity (62.4% similar) in 503 aa overlap (14-481:26-513)
10 20 30 40
pF1KE4 MAEQVALSRTQVCGILREELFQGDAFHQSDTHIFIIMGASGDLAKKKI
: :. . .:: : : .:..::.:::::: .
CCDS72 MLAEPFNWHPGMWNMLIVAMCLALLGCLQAQELQG---HVS----IILLGATGDLAKKYL
10 20 30 40 50
50 60 70 80 90 100
pF1KE4 YPTIWWLFRDGLLPENTFIV-GYARS------RLTVADIRKQSEPFFKATPEEKLKLEDF
. .. :. : ..: : : . .: . ... : : .: . . .:
CCDS72 WQGLFQLYLDEAGRGHSFSFHGAALTAPKQGQELMAKALESLSCPK-DMAPSHCAEHKDQ
60 70 80 90 100 110
110 120 130 140 150
pF1KE4 FARNSYVAGQYDDAASYQRLNSHMNAL--HLG-SQANRLFYLALPPTVYEAVTKNIHESC
: . : : : .:: ::. ..: : : .:.:.::...:: .:: ...::. ::
CCDS72 FLQLSQYR-QLKTAEDYQALNKDIEAQLQHAGLREAGRIFYFSVPPFAYEDIARNINSSC
120 130 140 150 160 170
160 170 180 190 200 210
pF1KE4 MSQIG-WNRIIVEKPFGRDLQSSDRLSNHISSLFREDQIYRIDHYLGKEMVQNLMVLRFA
: : :...:::::.: :...:.......:.:...::.::::::. : ... .:
CCDS72 RPGPGAWLRVVLEKPFGHDHFSAQQLATELGTFFQEEEMYRVDHYLGKQAVAQILPFRDQ
180 190 200 210 220 230
220 230 240 250 260 270
pF1KE4 NR-IFGPIWNRDNIACVILTFKEPFGTEGRGGYFDEFGIIRDVMQNHLLQMLCLVAMEKP
:: . .::: .. : . .:: .::: ....:.:.::::.:::: ..: ::::: :
CCDS72 NRKALDGLWNRHHVERVEIIMKETVDAEGRTSFYEEYGVIRDVLQNHLTEVLTLVAMELP
240 250 260 270 280 290
280 290 300 310 320 330
pF1KE4 ASTNSDD-VRDEKVKVLKCISEVQANNVVLGQYVGNPDGEGEATKGYLDDPTVPRGSTTA
...: . : .:..:.. . .: ...:.::: .. .: .. :. : . : :
CCDS72 HNVSSAEAVLRHKLQVFQALRGLQRGSAVVGQY----QSYSEQVRRELQKPDSFH-SLTP
300 310 320 330 340
340 350 360 370 380
pF1KE4 TFAAVVLYVENERWDGVPFILRCGKALNERKAEVRLQFHDVAGDI--------FHQQCKR
:::::.....: ::.:::::: ::::.:: . .:. :.. : . ..::
CCDS72 TFAAVLVHIDNLRWEGVPFILMSGKALDERVGYARILFKNQACCVQSEKHWAAAQSQCLP
350 360 370 380 390 400
390 400 410 420 430
pF1KE4 NELVIRVQPNE----AVYTKMMTKKPGMFFNPEESE----LDLTYGN------RYKNVKL
.::... .. :: .. .:.. . .: : : : .:. :. :.
CCDS72 RQLVFHIGHGDLGSPAVLVSRNLFRPSLPSSWKEMEGPPGLRL-FGSPLSDYYAYSPVRE
410 420 430 440 450 460
440 450 460 470 480 490
pF1KE4 PDAYERLILDVFCGSQMHFVRSDELREAWRIFTPLLHQIELEKPKPIPYIYGSRGPTEAD
::. :. .: : . :. ...: .: ..::::... . :. :
CCDS72 RDAHSVLLSHIFHGRKNFFITTENLLASWNFWTPLLESLAHKAPRLYPGGAENGRLLDFE
470 480 490 500 510 520
500 510
pF1KE4 ELMKRVGFQYEGTYKWVNPHKL
CCDS72 FSSGRLFFSQQQPEQLVPGPGPAPMPSDFQVLRAKYRESPLVSAWSEELISKLANDIEAT
530 540 550 560 570 580
515 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 00:46:00 2016 done: Sun Nov 6 00:46:01 2016
Total Scan time: 3.000 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]