Result of FASTA (omim) for
pFN21AE4472
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE4472, 493 aa
1>>>pF1KE4472 493 - 493 aa - 493 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.1795+/-0.000469; mu= 18.4117+/- 0.029
mean_var=60.6900+/-12.188, 0's: 0 Z-trim(107.1): 41 B-trim: 0 in 0/55
Lambda= 0.164633
statistics sampled from 15125 (15145) to 15125 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.525), E-opt: 0.2 (0.178), width: 16
Scan time: 8.670
The best scores are: opt bits E(85289)
NP_000069 (OMIM: 118470,143470) cholesteryl ester ( 493) 3175 763.3 0
XP_006721187 (OMIM: 118470,143470) PREDICTED: chol ( 266) 1604 390.1 4.3e-108
NP_001273014 (OMIM: 118470,143470) cholesteryl est ( 433) 1604 390.2 6.5e-108
NP_001716 (OMIM: 109195) bactericidal permeability ( 487) 410 106.6 1.7e-22
NP_006218 (OMIM: 172425) phospholipid transfer pro ( 493) 367 96.4 2e-19
NP_004130 (OMIM: 151990) lipopolysaccharide-bindin ( 481) 341 90.2 1.4e-17
NP_001229850 (OMIM: 172425) phospholipid transfer ( 405) 279 75.4 3.3e-13
NP_872617 (OMIM: 172425) phospholipid transfer pro ( 441) 253 69.3 2.6e-11
NP_001229849 (OMIM: 172425) phospholipid transfer ( 398) 249 68.3 4.6e-11
NP_777592 (OMIM: 614109) BPI fold-containing famil ( 507) 249 68.4 5.6e-11
XP_011528392 (OMIM: 614109) PREDICTED: BPI fold-co ( 507) 249 68.4 5.6e-11
XP_011528390 (OMIM: 614109) PREDICTED: BPI fold-co ( 507) 249 68.4 5.6e-11
XP_011528391 (OMIM: 614109) PREDICTED: BPI fold-co ( 507) 249 68.4 5.6e-11
XP_016884229 (OMIM: 614109) PREDICTED: BPI fold-co ( 450) 210 59.1 3.1e-08
NP_872599 (OMIM: 615717) BPI fold-containing famil ( 476) 143 43.2 0.002
>>NP_000069 (OMIM: 118470,143470) cholesteryl ester tran (493 aa)
initn: 3175 init1: 3175 opt: 3175 Z-score: 4074.2 bits: 763.3 E(85289): 0
Smith-Waterman score: 3175; 99.4% identity (99.8% similar) in 493 aa overlap (1-493:1-493)
10 20 30 40 50 60
pF1KE4 MLAATVLTLALLGNAHACSKGTSHEAGIVCRITKPALLVLNHETAKVIQTAFQRASYPDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MLAATVLTLALLGNAHACSKGTSHEAGIVCRITKPALLVLNHETAKVIQTAFQRASYPDI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 TGEKAMMLLGQVKYGLHNIQISHLSIASSQVELVEAKSIDVSIQNVSVVFKGTLKYGYTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TGEKAMMLLGQVKYGLHNIQISHLSIASSQVELVEAKSIDVSIQNVSVVFKGTLKYGYTT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 AWWLGIDQSIDFEIDSAIDLQINTQLTCDSGRVRTDAPDCYLSFHKLLLHLQGEREPGWI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 AWWLGIDQSIDFEIDSAIDLQINTQLTCDSGRVRTDAPDCYLSFHKLLLHLQGEREPGWI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 KQLFTNFISFTLKLVLKGQICKEINVISNIMADFVQTRAASILSDGDIGVDISLTGDPVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 KQLFTNFISFTLKLVLKGQICKEINVISNIMADFVQTRAASILSDGDIGVDISLTGDPVI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 TSSYLESHHKGHFIYKNVSEDLPLPTFSPTLLGDSRMLYFWFSERVFHSLAKVAFQDGRL
:.::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TASYLESHHKGHFIYKNVSEDLPLPTFSPTLLGDSRMLYFWFSERVFHSLAKVAFQDGRL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 MLSLMGDEFKAVLETWGFNTNQEIFQEVVGGFPSQAQVTVHCLKMPKISCQNKGVVVNSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MLSLMGDEFKAVLETWGFNTNQEIFQEVVGGFPSQAQVTVHCLKMPKISCQNKGVVVNSS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 VMVKFLFPRPDQQHSVAYTFEEDIVTTVQASYSKKKLFLSLLDFQITPKTVSNLTESSSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VMVKFLFPRPDQQHSVAYTFEEDIVTTVQASYSKKKLFLSLLDFQITPKTVSNLTESSSE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE4 SIQSFLQSMITAVGIPEVMSRLEVVFTALMNCKGVSLFDIINPEIITRDGFLLLQMDFGF
:.::::::::::::::::::::::::::::: ::::::::::::::::::::::::::::
NP_000 SVQSFLQSMITAVGIPEVMSRLEVVFTALMNSKGVSLFDIINPEIITRDGFLLLQMDFGF
430 440 450 460 470 480
490
pF1KE4 PEHLLVDFLQSLS
:::::::::::::
NP_000 PEHLLVDFLQSLS
490
>>XP_006721187 (OMIM: 118470,143470) PREDICTED: choleste (266 aa)
initn: 1604 init1: 1604 opt: 1604 Z-score: 2061.7 bits: 390.1 E(85289): 4.3e-108
Smith-Waterman score: 1604; 99.6% identity (100.0% similar) in 250 aa overlap (1-250:1-250)
10 20 30 40 50 60
pF1KE4 MLAATVLTLALLGNAHACSKGTSHEAGIVCRITKPALLVLNHETAKVIQTAFQRASYPDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MLAATVLTLALLGNAHACSKGTSHEAGIVCRITKPALLVLNHETAKVIQTAFQRASYPDI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 TGEKAMMLLGQVKYGLHNIQISHLSIASSQVELVEAKSIDVSIQNVSVVFKGTLKYGYTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TGEKAMMLLGQVKYGLHNIQISHLSIASSQVELVEAKSIDVSIQNVSVVFKGTLKYGYTT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 AWWLGIDQSIDFEIDSAIDLQINTQLTCDSGRVRTDAPDCYLSFHKLLLHLQGEREPGWI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AWWLGIDQSIDFEIDSAIDLQINTQLTCDSGRVRTDAPDCYLSFHKLLLHLQGEREPGWI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 KQLFTNFISFTLKLVLKGQICKEINVISNIMADFVQTRAASILSDGDIGVDISLTGDPVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KQLFTNFISFTLKLVLKGQICKEINVISNIMADFVQTRAASILSDGDIGVDISLTGDPVI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 TSSYLESHHKGHFIYKNVSEDLPLPTFSPTLLGDSRMLYFWFSERVFHSLAKVAFQDGRL
:.::::::::
XP_006 TASYLESHHKLQPYGSQESWGAPPHS
250 260
>>NP_001273014 (OMIM: 118470,143470) cholesteryl ester t (433 aa)
initn: 1604 init1: 1604 opt: 1604 Z-score: 2058.4 bits: 390.2 E(85289): 6.5e-108
Smith-Waterman score: 2637; 87.2% identity (87.6% similar) in 493 aa overlap (1-493:1-433)
10 20 30 40 50 60
pF1KE4 MLAATVLTLALLGNAHACSKGTSHEAGIVCRITKPALLVLNHETAKVIQTAFQRASYPDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLAATVLTLALLGNAHACSKGTSHEAGIVCRITKPALLVLNHETAKVIQTAFQRASYPDI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 TGEKAMMLLGQVKYGLHNIQISHLSIASSQVELVEAKSIDVSIQNVSVVFKGTLKYGYTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TGEKAMMLLGQVKYGLHNIQISHLSIASSQVELVEAKSIDVSIQNVSVVFKGTLKYGYTT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 AWWLGIDQSIDFEIDSAIDLQINTQLTCDSGRVRTDAPDCYLSFHKLLLHLQGEREPGWI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AWWLGIDQSIDFEIDSAIDLQINTQLTCDSGRVRTDAPDCYLSFHKLLLHLQGEREPGWI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 KQLFTNFISFTLKLVLKGQICKEINVISNIMADFVQTRAASILSDGDIGVDISLTGDPVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KQLFTNFISFTLKLVLKGQICKEINVISNIMADFVQTRAASILSDGDIGVDISLTGDPVI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 TSSYLESHHKGHFIYKNVSEDLPLPTFSPTLLGDSRMLYFWFSERVFHSLAKVAFQDGRL
:.::::::::
NP_001 TASYLESHHK--------------------------------------------------
250
310 320 330 340 350 360
pF1KE4 MLSLMGDEFKAVLETWGFNTNQEIFQEVVGGFPSQAQVTVHCLKMPKISCQNKGVVVNSS
::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ----------AVLETWGFNTNQEIFQEVVGGFPSQAQVTVHCLKMPKISCQNKGVVVNSS
260 270 280 290 300
370 380 390 400 410 420
pF1KE4 VMVKFLFPRPDQQHSVAYTFEEDIVTTVQASYSKKKLFLSLLDFQITPKTVSNLTESSSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VMVKFLFPRPDQQHSVAYTFEEDIVTTVQASYSKKKLFLSLLDFQITPKTVSNLTESSSE
310 320 330 340 350 360
430 440 450 460 470 480
pF1KE4 SIQSFLQSMITAVGIPEVMSRLEVVFTALMNCKGVSLFDIINPEIITRDGFLLLQMDFGF
:.::::::::::::::::::::::::::::: ::::::::::::::::::::::::::::
NP_001 SVQSFLQSMITAVGIPEVMSRLEVVFTALMNSKGVSLFDIINPEIITRDGFLLLQMDFGF
370 380 390 400 410 420
490
pF1KE4 PEHLLVDFLQSLS
:::::::::::::
NP_001 PEHLLVDFLQSLS
430
>>NP_001716 (OMIM: 109195) bactericidal permeability-inc (487 aa)
initn: 137 init1: 109 opt: 410 Z-score: 525.0 bits: 106.6 E(85289): 1.7e-22
Smith-Waterman score: 410; 23.0% identity (57.8% similar) in 488 aa overlap (4-477:16-483)
10 20 30 40
pF1KE4 MLAATVLTLALLGNAHACSKGTSHEAGIVCRITKPALLVLNHETAKVI
:....:. .:.: . . . :.: ::.. .: ... . ..
NP_001 MRENMARGPCNAPRWASLMVLVAIGTAVTAAV----NPGVVVRISQKGLDYASQQGTAAL
10 20 30 40 50
50 60 70 80 90 100
pF1KE4 QTAFQRASYPDITGEKAMMLLGQVKYGLHNIQISHLSIASSQVELVEAKSIDVSIQNVSV
: ..: . :: . . ::. .:......: .... :::. .: .. ::.:...
NP_001 QKELKRIKIPDYSDSFKIKHLGKGHYSFYSMDIREFQLPSSQISMVPNVGLKFSISNANI
60 70 80 90 100 110
110 120 130 140 150 160
pF1KE4 VFKGTLKYGYTTAWWLGIDQSIDFEIDS---AIDLQINTQLTCDSGRVRTDAPDCYLSFH
..: : . .: .. ..:. :.. . ::..... : ::. .: ..
NP_001 KISGKWK---AQKRFLKMSGNFDLSIEGMSISADLKLGSNPT--SGKPTITCSSCSSHIN
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE4 KLLLHLQGEREPGWIKQLFTNFISFTLKLVLKGQICKEI-NVISNIMADFVQTRAASILS
.. .:.. . . ::. ::: . : .:. ...:.:... : .:. . . :: .
NP_001 SVHVHIS-KSKVGWLIQLFHKKIESALRNKMNSQVCEKVTNSVSSELQPYFQTLPVMTKI
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE4 DGDIGVDISLTGDPVITSSYLESHHKGHFIYKNVSEDLPLPTFSPTLL----GDSRMLYF
:. :.. .:.. :. :. :. . ::.: .: . : : :.: .. . .::.:.
NP_001 DSVAGINYGLVAPPATTAETLDVQMKGEFYSEN--HHNP-PPFAPPVMEFPAAHDRMVYL
240 250 260 270 280
290 300 310 320 330
pF1KE4 WFSERVFHSLAKVAFQDGRLMLSLMGD----EFKAVLETWGFNTNQEIFQEVVGGFPS-Q
.:. :.. . : . : : ..: : : : : : :.: .. ::. ::. .
NP_001 GLSDYFFNTAGLVYQEAGVLKMTLRDDMIPKESKFRLTTKFFGT---FLPEVAKKFPNMK
290 300 310 320 330 340
340 350 360 370 380 390
pF1KE4 AQVTVHCLKMPKISCQNKGVVVNSSVMVKFLFPRPDQQHSVAYTFEEDIVTTVQASYSKK
:. : :..: : :.. .: :. . :... . . . . ....: ..
NP_001 IQIHVSASTPPHLSVQPTGLTFYPAVDVQAFAVLPNSSLASLFLIGMHTTGSMEVSAESN
350 360 370 380 390 400
400 410 420 430 440 450
pF1KE4 KLFLSL-LDFQITPKTVSNLTESSSESIQSFLQSMITAVGIPEVMSRLEVVFTALMNCKG
.: : :: . ::. : .:.... .. . .:.: .:. : : .
NP_001 RLVGELKLDRLLLELKHSNIGPFPVELLQDIMNYIVPILVLPRVNEKLQKGFP-LPTPAR
410 420 430 440 450 460
460 470 480 490
pF1KE4 VSLFDIINPEIITRDGFLLLQMDFGFPEHLLVDFLQSLS
:.:.... . ...:::. :
NP_001 VQLYNVV---LQPHQNFLLFGADVVYK
470 480
>>NP_006218 (OMIM: 172425) phospholipid transfer protein (493 aa)
initn: 208 init1: 99 opt: 367 Z-score: 469.7 bits: 96.4 E(85289): 2e-19
Smith-Waterman score: 382; 22.4% identity (55.1% similar) in 490 aa overlap (7-484:7-468)
10 20 30 40 50 60
pF1KE4 MLAATVLTLALLGNAHACSKGTSHEAGIVCRITKPALLVLNHETAKVIQTAFQRASYPDI
: ::::..::: : . :.:. :: ....: . .. .. . ::.
NP_006 MALFGALFLALLAGAHAEFPGCK------IRVTSKALELVKQEGLRFLEQELETITIPDL
10 20 30 40 50
70 80 90 100 110 120
pF1KE4 TGEKAMMLLGQVKYGLHNIQISHLSIASSQVELVEAKSIDVSIQNVSVVFKGTLKYGYTT
:.. :. :.. ......:...::.... . . ..: :.:. : :..
NP_006 RGKE-----GHFYYNISEVKVTELQLTSSELDFQPQQELMLQITNASL---G-LRFRRQL
60 70 80 90 100
130 140 150 160 170
pF1KE4 AWWLGIDQSIDFEIDSAIDLQINTQLTCD-SGRVRTDAPDCYLSFHKLLLHLQGEREPGW
.:. : . ..... . .:. : .::.... .: : .. . : .
NP_006 LYWFFYDGGYINASAEGVSIRTGLELSRDPAGRMKVSNVSCQASVSRMHAAFGGTFKK--
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE4 IKQLFTNFISFTLKLVLKGQICKEI----NVISNIMADFVQTRAASILSDGDIGVDISLT
. .....::. ....:. ::: . .:. : . : : .:. :. : .:.: ::
NP_006 VYDFLSTFITSGMRFLLNQQICPVLYHAGTVLLNSLLDTVPVRS-SV--DELVGIDYSLM
170 180 190 200 210 220
240 250 260 270 280 290
pF1KE4 GDPVITSSYLESHHKGHFI-YKNVSEDLPLPTFSPTLLGDSRMLYFWFSERVFHSLAKVA
::: ..: :. .: :. . . .:: . : : . ::.: ::: : : .
NP_006 KDPVASTSNLDMDFRGAFFPLTERNWSLPNRAVEPQLQEEERMVYVAFSEFFFDSAMESY
230 240 250 260 270 280
300 310 320 330 340 350
pF1KE4 FQDGRLMLSLMGD----EFKAVLETWGFNTNQEIFQEVVGGFPSQAQVTVHCLKMPKISC
:. : :.: :.:: .. .:.. :.. . :. : .. .. : :. .
NP_006 FRAGALQLLLVGDKVPHDLDMLLRATYFGSIVLLSPAVID---SPLKLELRVLAPPRCTI
290 300 310 320 330
360 370 380 390 400
pF1KE4 QNKGVVVNSSVMVKFLFPRPDQQHSVAYTFEEDIVTTVQASYSKKKLF--LSLLDFQITP
. .:.... .. : . . ::: . .. : ... . : : :.: :.:
NP_006 KPSGTTISVTASVTIALVPPDQPEVQLSSMTMDARLSAKMALRGKALRTQLDLRRFRIYS
340 350 360 370 380 390
410 420 430 440 450 460
pF1KE4 KTVSNLTESSSESIQSFLQSMITAVGIPEVMSRLEVVFTALMNCKGVSLFDIINPEIITR
. : : . .:. :..:. .:. .... . . .:... .. . ..
NP_006 NH-SALESLALIPLQAPLKTMLQ-IGVMPMLNERTWRGVQIPLPEGINF---VHEVVTNH
400 410 420 430 440 450
470 480 490
pF1KE4 DGFLLLQMDFGFPEHLLVDFLQSLS
::: . :. : . :
NP_006 AGFLTIGADLHFAKGLREVIEKNRPADVRASTAPTPSTAAV
460 470 480 490
>>NP_004130 (OMIM: 151990) lipopolysaccharide-binding pr (481 aa)
initn: 170 init1: 70 opt: 341 Z-score: 436.5 bits: 90.2 E(85289): 1.4e-17
Smith-Waterman score: 341; 23.0% identity (55.3% similar) in 461 aa overlap (7-460:11-461)
10 20 30 40 50
pF1KE4 MLAATVLTLALLGNAHACSKGTSHEAGIVCRITKPALLVLNHETAKVIQTAFQRAS
. :::: .. . :.. :.: ::: .: .: ..:. . : .
NP_004 MGALARALPSILLALLLTSTPEALGAN--PGLVARITDKGLQYAAQEGLLALQSELLRIT
10 20 30 40 50
60 70 80 90 100 110
pF1KE4 YPDITGEKAMMLLGQVKYGLHNIQISHLSIASSQVELVEAKSIDVSIQNVSVVFKGTLKY
::.::. . .:. .: .:...: . : .. : ......::.. :. .: :
NP_004 LPDFTGDLRIPHVGRGRYEFHSLNIHSCELLHSALRPVPGQGLSLSISDSSIRVQGRWKV
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE4 GYTTAWWLGIDQSIDFEIDSAIDLQINTQLTCDS-GRVRTDAPDCYLSFHKLLLHLQGER
. .. .. :.: . ..:....: : .: :: . : .: .. . . ..:.
NP_004 RKS---FFKLQGSFDVSV-KGISISVNLLLGSESSGRPTVTASSCSSDIADVEVDMSGDL
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE4 EPGWIKQLFTNFISFTLKLVLKGQICKEIN-VISNIMADFVQTRAASILSDGDIGVDISL
::. .:: : : .. ::...::. :. .:. . ..:: .. :. .: ::
NP_004 --GWLLNLFHNQIESKFQKVLESRICEMIQKSVSSDLQPYLQTLPVTTEIDSFADIDYSL
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE4 TGDPVITSSYLESHHKGHFIYKNVSEDLPLPTFSPTLLGD-SRMLYFWFSERVFHSLAKV
. : :...:: ::.....: . : . .: . ..:.:: .:. ::.. . :
NP_004 VEAPRATAQMLEVMFKGEIFHRNHRSPVTLLAAVMSLPEEHNKMVYFAISDYVFNTASLV
240 250 260 270 280 290
300 310 320 330 340
pF1KE4 AFQDGRLMLSLMGD----EFKAVLETWGFNTNQEIFQEVVGGFPSQAQVTVHCLKMPKIS
..: : .:. : . . : : .: . .. .. . : .: . ..:
NP_004 YHEEGYLNFSITDDMIPPDSNIRLTTKSFRPFVPRLARLYPNMNLELQGSVPSAPLLNFS
300 310 320 330 340 350
350 360 370 380 390 400
pF1KE4 CQNKGVVVNSSVMVKFLFPRPDQQHSVAYTFEEDIVTTVQASYSKKKLFLSLLDFQITPK
: .: . . :.: ... . .. .:. . :: ::. .. :
NP_004 PGNLSVDPYMEIDAFVLLPSSSKEPVFRLSVATNVSATLTFNTSKITGFLKPGKVKVELK
360 370 380 390 400 410
410 420 430 440 450 460
pF1KE4 TVSNLTESSSESIQSFLQSMITAVGIPEVMSRLEVVFTALMNCKGVSLFDIINPEIITRD
:.. ..: ....:. .: . :. ..: : : : :.:.:.
NP_004 E-SKVGLFNAELLEALLNYYILNTFYPKFNDKLAEGFP-LPLLKRVQLYDLGLQIHKDFL
420 430 440 450 460 470
470 480 490
pF1KE4 GFLLLQMDFGFPEHLLVDFLQSLS
NP_004 FLGANVQYMRV
480
>>NP_001229850 (OMIM: 172425) phospholipid transfer prot (405 aa)
initn: 179 init1: 99 opt: 279 Z-score: 358.1 bits: 75.4 E(85289): 3.3e-13
Smith-Waterman score: 279; 21.9% identity (53.3% similar) in 383 aa overlap (114-484:11-380)
90 100 110 120 130 140
pF1KE4 LSIASSQVELVEAKSIDVSIQNVSVVFKGTLKYGYTTAWWLGIDQSIDFEIDSAIDLQIN
:.. .:. : . ..... .
NP_001 MLQITNASLGLRFRRQLLYWFFYDGGYINASAEGVSIRTG
10 20 30 40
150 160 170 180 190 200
pF1KE4 TQLTCD-SGRVRTDAPDCYLSFHKLLLHLQGEREPGWIKQLFTNFISFTLKLVLKGQICK
.:. : .::.... .: : .. . : . . .....::. ....:. :::
NP_001 LELSRDPAGRMKVSNVSCQASVSRMHAAFGGTFKK--VYDFLSTFITSGMRFLLNQQICP
50 60 70 80 90
210 220 230 240 250
pF1KE4 EI----NVISNIMADFVQTRAASILSDGDIGVDISLTGDPVITSSYLESHHKGHFI-YKN
. .:. : . : : .:. :. : .:.: :: ::: ..: :. .: :. .
NP_001 VLYHAGTVLLNSLLDTVPVRS-SV--DELVGIDYSLMKDPVASTSNLDMDFRGAFFPLTE
100 110 120 130 140 150
260 270 280 290 300 310
pF1KE4 VSEDLPLPTFSPTLLGDSRMLYFWFSERVFHSLAKVAFQDGRLMLSLMGD----EFKAVL
. .:: . : : . ::.: ::: : : . :. : :.: :.:: .. .:
NP_001 RNWSLPNRAVEPQLQEEERMVYVAFSEFFFDSAMESYFRAGALQLLLVGDKVPHDLDMLL
160 170 180 190 200 210
320 330 340 350 360 370
pF1KE4 ETWGFNTNQEIFQEVVGGFPSQAQVTVHCLKMPKISCQNKGVVVNSSVMVKFLFPRPDQQ
.. :.. . :. : .. .. : :. . . .:.... .. : . . :::
NP_001 RATYFGSIVLLSPAVI---DSPLKLELRVLAPPRCTIKPSGTTISVTASVTIALVPPDQP
220 230 240 250 260 270
380 390 400 410 420 430
pF1KE4 HSVAYTFEEDIVTTVQASYSKKKLF--LSLLDFQITPKTVSNLTESSSESIQSFLQSMIT
. .. : ... . : : :.: :.: . : : . .:. :..:.
NP_001 EVQLSSMTMDARLSAKMALRGKALRTQLDLRRFRIYSNH-SALESLALIPLQAPLKTMLQ
280 290 300 310 320 330
440 450 460 470 480 490
pF1KE4 AVGIPEVMSRLEVVFTALMNCKGVSLFDIINPEIITRDGFLLLQMDFGFPEHLLVDFLQS
.:. .... . . .:... .. . .. ::: . :. : . :
NP_001 -IGVMPMLNERTWRGVQIPLPEGINF---VHEVVTNHAGFLTIGADLHFAKGLREVIEKN
340 350 360 370 380
pF1KE4 LS
NP_001 RPADVRASTAPTPSTAAV
390 400
>>NP_872617 (OMIM: 172425) phospholipid transfer protein (441 aa)
initn: 208 init1: 99 opt: 253 Z-score: 324.1 bits: 69.3 E(85289): 2.6e-11
Smith-Waterman score: 260; 21.3% identity (49.7% similar) in 489 aa overlap (7-484:7-416)
10 20 30 40 50 60
pF1KE4 MLAATVLTLALLGNAHACSKGTSHEAGIVCRITKPALLVLNHETAKVIQTAFQRASYPDI
: ::::..::: : . :.:. :: ....: . .. .. . ::.
NP_872 MALFGALFLALLAGAHAEFPGCK------IRVTSKALELVKQEGLRFLEQELETITIPDL
10 20 30 40 50
70 80 90 100 110 120
pF1KE4 TGEKAMMLLGQVKYGLHNIQISHLSIASSQVELVEAKSIDVSIQNVSVVFKGTLKYGYTT
:.. :. :.. ......:...::.... . . ..: :.:. .. . :
NP_872 RGKE-----GHFYYNISEVKVTELQLTSSELDFQPQQELMLQITNASLGLRFRRQLLY--
60 70 80 90 100
130 140 150 160 170 180
pF1KE4 AWWLGIDQSIDFEIDSAIDLQINTQLTCDSGRVRTDAPDCYLSFHKLLLHLQGEREPGWI
:.: . ::
NP_872 -WFLKV---YDF------------------------------------------------
110
190 200 210 220 230
pF1KE4 KQLFTNFISFTLKLVLKGQICKEI----NVISNIMADFVQTRAASILSDGDIGVDISLTG
...::. ....:. ::: . .:. : . : : .:. :. : .:.: ::
NP_872 ---LSTFITSGMRFLLNQQICPVLYHAGTVLLNSLLDTVPVRS-SV--DELVGIDYSLMK
120 130 140 150 160
240 250 260 270 280 290
pF1KE4 DPVITSSYLESHHKGHFI-YKNVSEDLPLPTFSPTLLGDSRMLYFWFSERVFHSLAKVAF
::: ..: :. .: :. . . .:: . : : . ::.: ::: : : . :
NP_872 DPVASTSNLDMDFRGAFFPLTERNWSLPNRAVEPQLQEEERMVYVAFSEFFFDSAMESYF
170 180 190 200 210 220
300 310 320 330 340 350
pF1KE4 QDGRLMLSLMGD----EFKAVLETWGFNTNQEIFQEVVGGFPSQAQVTVHCLKMPKISCQ
. : :.: :.:: .. .:.. :.. . :. : .. .. : :. . .
NP_872 RAGALQLLLVGDKVPHDLDMLLRATYFGSIVLLSPAVID---SPLKLELRVLAPPRCTIK
230 240 250 260 270 280
360 370 380 390 400
pF1KE4 NKGVVVNSSVMVKFLFPRPDQQHSVAYTFEEDIVTTVQASYSKKKLF--LSLLDFQITPK
.:.... .. : . . ::: . .. : ... . : : :.: :.: .
NP_872 PSGTTISVTASVTIALVPPDQPEVQLSSMTMDARLSAKMALRGKALRTQLDLRRFRIYSN
290 300 310 320 330 340
410 420 430 440 450 460
pF1KE4 TVSNLTESSSESIQSFLQSMITAVGIPEVMSRLEVVFTALMNCKGVSLFDIINPEIITRD
: : . .:. :..:. .:. .... . . .:... .. . ..
NP_872 H-SALESLALIPLQAPLKTMLQ-IGVMPMLNERTWRGVQIPLPEGINF---VHEVVTNHA
350 360 370 380 390 400
470 480 490
pF1KE4 GFLLLQMDFGFPEHLLVDFLQSLS
::: . :. : . :
NP_872 GFLTIGADLHFAKGLREVIEKNRPADVRASTAPTPSTAAV
410 420 430 440
>>NP_001229849 (OMIM: 172425) phospholipid transfer prot (398 aa)
initn: 208 init1: 99 opt: 249 Z-score: 319.7 bits: 68.3 E(85289): 4.6e-11
Smith-Waterman score: 249; 23.4% identity (54.1% similar) in 316 aa overlap (180-484:69-373)
150 160 170 180 190 200
pF1KE4 SGRVRTDAPDCYLSFHKLLLHLQGEREPGWIKQLFTNFISFTLKLVLKGQICKEI----N
. .....::. ....:. ::: . .
NP_001 LRFLEQELETITIPDLRGKEGHFYYNISEKVYDFLSTFITSGMRFLLNQQICPVLYHAGT
40 50 60 70 80 90
210 220 230 240 250 260
pF1KE4 VISNIMADFVQTRAASILSDGDIGVDISLTGDPVITSSYLESHHKGHFI-YKNVSEDLPL
:. : . : : .:.. : .:.: :: ::: ..: :. .: :. . . .::
NP_001 VLLNSLLDTVPVRSSV---DELVGIDYSLMKDPVASTSNLDMDFRGAFFPLTERNWSLPN
100 110 120 130 140 150
270 280 290 300 310 320
pF1KE4 PTFSPTLLGDSRMLYFWFSERVFHSLAKVAFQDGRLMLSLMGD----EFKAVLETWGFNT
. : : . ::.: ::: : : . :. : :.: :.:: .. .:.. :..
NP_001 RAVEPQLQEEERMVYVAFSEFFFDSAMESYFRAGALQLLLVGDKVPHDLDMLLRATYFGS
160 170 180 190 200 210
330 340 350 360 370 380
pF1KE4 NQEIFQEVVGGFPSQAQVTVHCLKMPKISCQNKGVVVNSSVMVKFLFPRPDQQHSVAYTF
. :. . : . .. : : :. . . .:.... .. : . . ::: . ..
NP_001 IVLLSPAVIDS-PLKLELRV--LAPPRCTIKPSGTTISVTASVTIALVPPDQPEVQLSSM
220 230 240 250 260 270
390 400 410 420 430
pF1KE4 EEDIVTTVQASYSKKKLF--LSLLDFQITPKTVSNLTESSSESIQSFLQSMITAVGIPEV
: ... . : : :.: :.: . : : . .:. :..:. .:. .
NP_001 TMDARLSAKMALRGKALRTQLDLRRFRIYSNH-SALESLALIPLQAPLKTMLQ-IGVMPM
280 290 300 310 320 330
440 450 460 470 480 490
pF1KE4 MSRLEVVFTALMNCKGVSLFDIINPEIITRDGFLLLQMDFGFPEHLLVDFLQSLS
... . . .:. .... . .. ::: . :. : . :
NP_001 LNERTWRGVQIPLPEGI---NFVHEVVTNHAGFLTIGADLHFAKGLREVIEKNRPADVRA
340 350 360 370 380
NP_001 STAPTPSTAAV
390
>>NP_777592 (OMIM: 614109) BPI fold-containing family C (507 aa)
initn: 134 init1: 71 opt: 249 Z-score: 318.1 bits: 68.4 E(85289): 5.6e-11
Smith-Waterman score: 249; 24.0% identity (54.4% similar) in 491 aa overlap (11-480:14-478)
10 20 30 40 50
pF1KE4 MLAATVLTLALLGNAHACSKGTSHEAGIVCRITKPALLVLNHETAKVIQTAFQRASY
:: : .. :. : . :: :::. :: . :.:. ... .
NP_777 MCTKTIPVLWGCFLLWNLYVSSSQTIYP-GIKARITQRALDYGVQAGMKMIEQMLKEKKL
10 20 30 40 50
60 70 80 90 100 110
pF1KE4 PDITGEKAMMLL--GQVKYGLHNIQISHLSIASSQVELVEAKSIDVSIQNVSVVFKGTLK
::..: ... .: :.:.. ::.:: .:. .... .: . .: . .. .. . .
NP_777 PDLSGSESLEFLKVDYVNYNFSNIKISAFSFPNTSLAFVPGVGIKALTNHGTANI--STD
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE4 YGYTTAWWLGIDQSIDFEIDSAIDLQINTQLTCDSGRVRTDAPDCYLSFHKLLLHLQGER
.:. . . . :. .... : : :. ::: .. . . ..::
NP_777 WGFESPLFQDTG-GADLFLSGVYFTGIIILTRNDFGHPTLKLQDCYAQLSHAHVSFSGE-
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE4 EPGWIKQLFTNFISFTLKLVLKG---QICKEINVISNIMADFVQTRAASILS--DGDIGV
.. :...: : .::. ..: : :.. : .. . .:. :. .
NP_777 ----LSVLYNSFAEPMEKPILKNLNEMLCPIIA--SEVKALNANLSTLEVLTKIDNYTLL
180 190 200 210 220
240 250 260 270 280
pF1KE4 DISLTGDPVITSSYLESHHKGHFIYKNVSEDLPLPTFSPT--LLGD--SRMLYFWFSERV
: :: ..: :: .::. . :: : : :.: : :::. .: . . :::. ..:
NP_777 DYSLISSPEITENYLDLNLKGVF-YP--LENLTDPPFSPVPFVLPERSNSMLYIGIAEYF
230 240 250 260 270 280
290 300 310 320 330 340
pF1KE4 FHSLAKVAFQDGRLMLSLMGDEFKA--VLETWGFNTNQEIFQEVVGGFPSQA-QVTVHCL
:.: . . : : . ..: .:.. : .. :... . :. . :: .: .
NP_777 FKSASFAHFTAGVFNVTLSTEEISNHFVQNSQGLGNVLSRIAEIY--ILSQPFMVRIMAT
290 300 310 320 330 340
350 360 370 380 390
pF1KE4 KMPKISCQ--NKGVVVNSSVMVKFLFPRPDQQHSVAYTFEEDIV--TTVQASYSKKKLF-
. : :. : : . . .:.: .. .: .. .: :.: :.: ..:
NP_777 EPPIINLQPGNFTLDIPASIM---MLTQP-KNSTVETIVSMDFVASTSVGLVILGQRLVC
350 360 370 380 390 400
400 410 420 430 440 450
pF1KE4 -LSLLDFQIT-PKTVSNLTESSSESIQSFLQSMITAVGIPEVMSRLEVVFTALMNCKGVS
::: :... :. :: .. ....:.:.. .: . ..:. : : : .
NP_777 SLSLNRFRLALPE--SNRSNIEVLRFENILSSILHFGVLPLANAKLQQGFP-LSNPHK--
410 420 430 440 450
460 470 480 490
pF1KE4 LFDIINPEIITRDGFLLLQMDFGFPEHLLVDFLQSLS
: ..: .: . .::::.. :. .
NP_777 -FLFVNSDIEVLEGFLLISTDLKYETSSKQQPSFHVWEGLNLISRQWRGKSAP
460 470 480 490 500
493 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 00:54:11 2016 done: Sun Nov 6 00:54:12 2016
Total Scan time: 8.670 Total Display time: 0.060
Function used was FASTA [36.3.4 Apr, 2011]