Result of FASTA (omim) for
pFN21AE4471
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE4471, 492 aa
1>>>pF1KE4471 492 - 492 aa - 492 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.2328+/-0.00044; mu= 13.0092+/- 0.027
mean_var=77.6673+/-15.872, 0's: 0 Z-trim(110.2): 163 B-trim: 0 in 0/53
Lambda= 0.145531
statistics sampled from 18345 (18519) to 18345 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.562), E-opt: 0.2 (0.217), width: 16
Scan time: 5.270
The best scores are: opt bits E(85289)
NP_000799 (OMIM: 305660) gamma-aminobutyric acid r ( 492) 3225 687.2 2.8e-197
XP_006724874 (OMIM: 305660) PREDICTED: gamma-amino ( 340) 2076 445.9 8.4e-125
NP_001158509 (OMIM: 137142) gamma-aminobutyric aci ( 462) 1913 411.7 2.2e-114
NP_000801 (OMIM: 137142) gamma-aminobutyric acid r ( 462) 1913 411.7 2.2e-114
XP_006720522 (OMIM: 137142) PREDICTED: gamma-amino ( 462) 1913 411.7 2.2e-114
XP_005268315 (OMIM: 137142) PREDICTED: gamma-amino ( 462) 1913 411.7 2.2e-114
NP_001121116 (OMIM: 137160,611136,615744) gamma-am ( 456) 1907 410.5 5.3e-114
NP_001121115 (OMIM: 137160,611136,615744) gamma-am ( 456) 1907 410.5 5.3e-114
NP_001121117 (OMIM: 137160,611136,615744) gamma-am ( 456) 1907 410.5 5.3e-114
NP_001121120 (OMIM: 137160,611136,615744) gamma-am ( 456) 1907 410.5 5.3e-114
NP_000797 (OMIM: 137160,611136,615744) gamma-amino ( 456) 1907 410.5 5.3e-114
NP_001107647 (OMIM: 103780,137140) gamma-aminobuty ( 451) 1905 410.0 7e-114
XP_016863472 (OMIM: 103780,137140) PREDICTED: gamm ( 451) 1905 410.0 7e-114
NP_000798 (OMIM: 103780,137140) gamma-aminobutyric ( 451) 1905 410.0 7e-114
XP_016863471 (OMIM: 103780,137140) PREDICTED: gamm ( 451) 1905 410.0 7e-114
XP_011511977 (OMIM: 103780,137140) PREDICTED: gamm ( 511) 1869 402.5 1.5e-111
NP_001317619 (OMIM: 103780,137140) gamma-aminobuty ( 511) 1869 402.5 1.5e-111
NP_000802 (OMIM: 137143) gamma-aminobutyric acid r ( 453) 1695 365.9 1.3e-100
NP_001191195 (OMIM: 137141) gamma-aminobutyric aci ( 535) 1644 355.3 2.6e-97
NP_000800 (OMIM: 137141) gamma-aminobutyric acid r ( 554) 1644 355.3 2.6e-97
XP_005248137 (OMIM: 103780,137140) PREDICTED: gamm ( 396) 1613 348.7 1.8e-95
NP_001273756 (OMIM: 103780,137140) gamma-aminobuty ( 456) 1577 341.2 3.8e-93
XP_016877544 (OMIM: 137142) PREDICTED: gamma-amino ( 306) 1465 317.6 3.2e-86
XP_016877545 (OMIM: 137142) PREDICTED: gamma-amino ( 306) 1465 317.6 3.2e-86
NP_944494 (OMIM: 137164,607681,611277) gamma-amino ( 475) 1253 273.1 1.2e-72
NP_150092 (OMIM: 600233) gamma-aminobutyric acid r ( 467) 1185 258.9 2.3e-68
NP_000807 (OMIM: 137164,607681,611277) gamma-amino ( 467) 1182 258.2 3.6e-68
NP_775807 (OMIM: 137166) gamma-aminobutyric acid r ( 465) 1173 256.3 1.3e-67
XP_011519732 (OMIM: 600233) PREDICTED: gamma-amino ( 473) 1129 247.1 8.1e-65
NP_001191196 (OMIM: 137141) gamma-aminobutyric aci ( 484) 989 217.7 5.8e-56
NP_004952 (OMIM: 300093) gamma-aminobutyric acid r ( 506) 973 214.4 6.2e-55
XP_016877548 (OMIM: 600233) PREDICTED: gamma-amino ( 355) 938 207.0 7.4e-53
NP_001139512 (OMIM: 138491,149400) glycine recepto ( 457) 937 206.8 1.1e-52
NP_006520 (OMIM: 600421) glycine receptor subunit ( 464) 920 203.2 1.3e-51
XP_016863479 (OMIM: 137166) PREDICTED: gamma-amino ( 336) 916 202.3 1.7e-51
XP_016864119 (OMIM: 600421) PREDICTED: glycine rec ( 424) 917 202.6 1.8e-51
XP_016877547 (OMIM: 600233) PREDICTED: gamma-amino ( 361) 891 197.1 7e-50
NP_001243632 (OMIM: 137161) gamma-aminobutyric aci ( 462) 859 190.4 9.2e-48
NP_068712 (OMIM: 137192,612269,617113) gamma-amino ( 473) 857 190.0 1.3e-47
NP_000805 (OMIM: 137192,612269,617113) gamma-amino ( 473) 856 189.8 1.5e-47
XP_011543797 (OMIM: 305990) PREDICTED: glycine rec ( 436) 847 187.9 5e-47
XP_006724550 (OMIM: 305990) PREDICTED: glycine rec ( 436) 847 187.9 5e-47
XP_011543798 (OMIM: 305990) PREDICTED: glycine rec ( 436) 847 187.9 5e-47
NP_002054 (OMIM: 305990) glycine receptor subunit ( 452) 847 187.9 5.2e-47
NP_001112357 (OMIM: 305990) glycine receptor subun ( 452) 847 187.9 5.2e-47
NP_000162 (OMIM: 138491,149400) glycine receptor s ( 449) 846 187.7 6e-47
XP_016864838 (OMIM: 138491,149400) PREDICTED: glyc ( 465) 846 187.7 6.1e-47
XP_016856425 (OMIM: 137163,613060) PREDICTED: gamm ( 687) 848 188.2 6.5e-47
NP_001036008 (OMIM: 600421) glycine receptor subun ( 449) 845 187.5 6.9e-47
XP_016884916 (OMIM: 305990) PREDICTED: glycine rec ( 452) 845 187.5 6.9e-47
>>NP_000799 (OMIM: 305660) gamma-aminobutyric acid recep (492 aa)
initn: 3225 init1: 3225 opt: 3225 Z-score: 3662.7 bits: 687.2 E(85289): 2.8e-197
Smith-Waterman score: 3225; 99.8% identity (99.8% similar) in 492 aa overlap (1-492:1-492)
10 20 30 40 50 60
pF1KE4 MIITQTSHCYMTSLGILFLINILPGTTGQGESRRQEPGDFVKQDIGGLSPKHAPDIPDDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MIITQTSHCYMTSLGILFLINILPGTTGQGESRRQEPGDFVKQDIGGLSPKHAPDIPDDS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 TDNITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TDNITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 TWHDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLP
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TWHDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 YTMRLTIHAECPMHLEDFPMDVHACPLKFGSYAYTTAEVVYSWTLGKNKSVEVAQDGSRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 YTMRLTIHAECPMHLEDFPMDVHACPLKFGSYAYTTAEVVYSWTLGKNKSVEVAQDGSRL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 NQYDLLGHVVGTEIIRSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 NQYDLLGHVVGTEIIRSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 RESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 RESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVN
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 YFTKRSWAWEGKKVPEALEMKKKTPAAPAKKTSTTFNIVGTTYPINLAKDTEFSTISKGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 YFTKRSWAWEGKKVPEALEMKKKTPAAPAKKTSTTFNIVGTTYPINLAKDTEFSTISKGA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE4 APSASSTPTIIASPKATYVQDSPTETKTYNSVSKVDKISRIIFPVLFAIFNLVYWATYVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 APSASSTPTIIASPKATYVQDSPTETKTYNSVSKVDKISRIIFPVLFAIFNLVYWATYVN
430 440 450 460 470 480
490
pF1KE4 RESAIKGMIRKQ
::::::::::::
NP_000 RESAIKGMIRKQ
490
>>XP_006724874 (OMIM: 305660) PREDICTED: gamma-aminobuty (340 aa)
initn: 2076 init1: 2076 opt: 2076 Z-score: 2361.6 bits: 445.9 E(85289): 8.4e-125
Smith-Waterman score: 2076; 99.7% identity (99.7% similar) in 310 aa overlap (1-310:1-310)
10 20 30 40 50 60
pF1KE4 MIITQTSHCYMTSLGILFLINILPGTTGQGESRRQEPGDFVKQDIGGLSPKHAPDIPDDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MIITQTSHCYMTSLGILFLINILPGTTGQGESRRQEPGDFVKQDIGGLSPKHAPDIPDDS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 TDNITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TDNITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 TWHDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLP
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TWHDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 YTMRLTIHAECPMHLEDFPMDVHACPLKFGSYAYTTAEVVYSWTLGKNKSVEVAQDGSRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YTMRLTIHAECPMHLEDFPMDVHACPLKFGSYAYTTAEVVYSWTLGKNKSVEVAQDGSRL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 NQYDLLGHVVGTEIIRSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NQYDLLGHVVGTEIIRSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 RESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVN
::::::::::
XP_006 RESVPARTVFEENTSSPSKENQHYLQHRGDHLSHQPGQGH
310 320 330 340
>>NP_001158509 (OMIM: 137142) gamma-aminobutyric acid re (462 aa)
initn: 2114 init1: 1875 opt: 1913 Z-score: 2174.4 bits: 411.7 E(85289): 2.2e-114
Smith-Waterman score: 2112; 73.0% identity (87.8% similar) in 441 aa overlap (47-487:29-457)
20 30 40 50 60 70
pF1KE4 LFLINILPGTTGQGESRRQEPGDFVKQDIGGLSPKHAPDIPDDSTDNITIFTRILDRLLD
:.: . .. :...::::::::::: :::
NP_001 MDNGMFSGFIMIKNLLLFCISMNLSSHFGFSQMPTSSVKDETNDNITIFTRILDGLLD
10 20 30 40 50
80 90 100 110 120 130
pF1KE4 GYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQTWHDERLKFDGPMKIL
:::::::::::. .:.:.::::::::::::::.:::::::::::.:.::::.: :::. :
NP_001 GYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQSWKDERLRFKGPMQRL
60 70 80 90 100 110
140 150 160 170 180 190
pF1KE4 PLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLPYTMRLTIHAECPMHLE
:::::::::::::::::::::::.::::::::::::: :.::: ::::::: :::::.::
NP_001 PLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLYTMRLTISAECPMQLE
120 130 140 150 160 170
200 210 220 230 240 250
pF1KE4 DFPMDVHACPLKFGSYAYTTAEVVYSWTLGKNKSVEVAQDGSRLNQYDLLGHVVGTEIIR
:::::.:::::::::::: ..:::: :: :..::: ::.:::::::: :.:..:::: :
NP_001 DFPMDAHACPLKFGSYAYPNSEVVYVWTNGSTKSVVVAEDGSRLNQYHLMGQTVGTENIS
180 190 200 210 220 230
260 270 280 290 300 310
pF1KE4 SSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVL
.:::::..::.:::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TSTGEYTIMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVL
240 250 260 270 280 290
320 330 340 350 360 370
pF1KE4 TMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRSWAWEGKKVPE
:::::::::::::::::::::::::::::::::::::::::::::::::.:::.:::. :
NP_001 TMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGWAWDGKKALE
300 310 320 330 340 350
380 390 400 410 420 430
pF1KE4 ALEMKKKTPAAPAKKTSTTFNIVGTTYPINLAKDTEFSTISKGAAPSASSTPTIIASPKA
: ..::: . .:....:. ..: :. :. .:...:. : . : :
NP_001 AAKIKKKREVI-LNKSTNAFTTGKMSHPPNIPKEQ---------TPAGTSNTTSV-SVKP
360 370 380 390 400
440 450 460 470 480 490
pF1KE4 TYVQDSPTETKTYNSVSKVDKISRIIFPVLFAIFNLVYWATYVNRESAIKGMIRKQ
. . : .. :::::.::.::.:::.:::::. :::::::::.::: .:::
NP_001 SEEKTSESK-KTYNSISKIDKMSRIVFPVLFGTFNLVYWATYLNREPVIKGAASPK
410 420 430 440 450 460
>>NP_000801 (OMIM: 137142) gamma-aminobutyric acid recep (462 aa)
initn: 2114 init1: 1875 opt: 1913 Z-score: 2174.4 bits: 411.7 E(85289): 2.2e-114
Smith-Waterman score: 2112; 73.0% identity (87.8% similar) in 441 aa overlap (47-487:29-457)
20 30 40 50 60 70
pF1KE4 LFLINILPGTTGQGESRRQEPGDFVKQDIGGLSPKHAPDIPDDSTDNITIFTRILDRLLD
:.: . .. :...::::::::::: :::
NP_000 MDNGMFSGFIMIKNLLLFCISMNLSSHFGFSQMPTSSVKDETNDNITIFTRILDGLLD
10 20 30 40 50
80 90 100 110 120 130
pF1KE4 GYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQTWHDERLKFDGPMKIL
:::::::::::. .:.:.::::::::::::::.:::::::::::.:.::::.: :::. :
NP_000 GYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQSWKDERLRFKGPMQRL
60 70 80 90 100 110
140 150 160 170 180 190
pF1KE4 PLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLPYTMRLTIHAECPMHLE
:::::::::::::::::::::::.::::::::::::: :.::: ::::::: :::::.::
NP_000 PLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLYTMRLTISAECPMQLE
120 130 140 150 160 170
200 210 220 230 240 250
pF1KE4 DFPMDVHACPLKFGSYAYTTAEVVYSWTLGKNKSVEVAQDGSRLNQYDLLGHVVGTEIIR
:::::.:::::::::::: ..:::: :: :..::: ::.:::::::: :.:..:::: :
NP_000 DFPMDAHACPLKFGSYAYPNSEVVYVWTNGSTKSVVVAEDGSRLNQYHLMGQTVGTENIS
180 190 200 210 220 230
260 270 280 290 300 310
pF1KE4 SSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVL
.:::::..::.:::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TSTGEYTIMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVL
240 250 260 270 280 290
320 330 340 350 360 370
pF1KE4 TMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRSWAWEGKKVPE
:::::::::::::::::::::::::::::::::::::::::::::::::.:::.:::. :
NP_000 TMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGWAWDGKKALE
300 310 320 330 340 350
380 390 400 410 420 430
pF1KE4 ALEMKKKTPAAPAKKTSTTFNIVGTTYPINLAKDTEFSTISKGAAPSASSTPTIIASPKA
: ..::: . .:....:. ..: :. :. .:...:. : . : :
NP_000 AAKIKKKREVI-LNKSTNAFTTGKMSHPPNIPKEQ---------TPAGTSNTTSV-SVKP
360 370 380 390 400
440 450 460 470 480 490
pF1KE4 TYVQDSPTETKTYNSVSKVDKISRIIFPVLFAIFNLVYWATYVNRESAIKGMIRKQ
. . : .. :::::.::.::.:::.:::::. :::::::::.::: .:::
NP_000 SEEKTSESK-KTYNSISKIDKMSRIVFPVLFGTFNLVYWATYLNREPVIKGAASPK
410 420 430 440 450 460
>>XP_006720522 (OMIM: 137142) PREDICTED: gamma-aminobuty (462 aa)
initn: 2114 init1: 1875 opt: 1913 Z-score: 2174.4 bits: 411.7 E(85289): 2.2e-114
Smith-Waterman score: 2112; 73.0% identity (87.8% similar) in 441 aa overlap (47-487:29-457)
20 30 40 50 60 70
pF1KE4 LFLINILPGTTGQGESRRQEPGDFVKQDIGGLSPKHAPDIPDDSTDNITIFTRILDRLLD
:.: . .. :...::::::::::: :::
XP_006 MDNGMFSGFIMIKNLLLFCISMNLSSHFGFSQMPTSSVKDETNDNITIFTRILDGLLD
10 20 30 40 50
80 90 100 110 120 130
pF1KE4 GYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQTWHDERLKFDGPMKIL
:::::::::::. .:.:.::::::::::::::.:::::::::::.:.::::.: :::. :
XP_006 GYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQSWKDERLRFKGPMQRL
60 70 80 90 100 110
140 150 160 170 180 190
pF1KE4 PLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLPYTMRLTIHAECPMHLE
:::::::::::::::::::::::.::::::::::::: :.::: ::::::: :::::.::
XP_006 PLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLYTMRLTISAECPMQLE
120 130 140 150 160 170
200 210 220 230 240 250
pF1KE4 DFPMDVHACPLKFGSYAYTTAEVVYSWTLGKNKSVEVAQDGSRLNQYDLLGHVVGTEIIR
:::::.:::::::::::: ..:::: :: :..::: ::.:::::::: :.:..:::: :
XP_006 DFPMDAHACPLKFGSYAYPNSEVVYVWTNGSTKSVVVAEDGSRLNQYHLMGQTVGTENIS
180 190 200 210 220 230
260 270 280 290 300 310
pF1KE4 SSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVL
.:::::..::.:::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TSTGEYTIMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVL
240 250 260 270 280 290
320 330 340 350 360 370
pF1KE4 TMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRSWAWEGKKVPE
:::::::::::::::::::::::::::::::::::::::::::::::::.:::.:::. :
XP_006 TMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGWAWDGKKALE
300 310 320 330 340 350
380 390 400 410 420 430
pF1KE4 ALEMKKKTPAAPAKKTSTTFNIVGTTYPINLAKDTEFSTISKGAAPSASSTPTIIASPKA
: ..::: . .:....:. ..: :. :. .:...:. : . : :
XP_006 AAKIKKKREVI-LNKSTNAFTTGKMSHPPNIPKEQ---------TPAGTSNTTSV-SVKP
360 370 380 390 400
440 450 460 470 480 490
pF1KE4 TYVQDSPTETKTYNSVSKVDKISRIIFPVLFAIFNLVYWATYVNRESAIKGMIRKQ
. . : .. :::::.::.::.:::.:::::. :::::::::.::: .:::
XP_006 SEEKTSESK-KTYNSISKIDKMSRIVFPVLFGTFNLVYWATYLNREPVIKGAASPK
410 420 430 440 450 460
>>XP_005268315 (OMIM: 137142) PREDICTED: gamma-aminobuty (462 aa)
initn: 2114 init1: 1875 opt: 1913 Z-score: 2174.4 bits: 411.7 E(85289): 2.2e-114
Smith-Waterman score: 2112; 73.0% identity (87.8% similar) in 441 aa overlap (47-487:29-457)
20 30 40 50 60 70
pF1KE4 LFLINILPGTTGQGESRRQEPGDFVKQDIGGLSPKHAPDIPDDSTDNITIFTRILDRLLD
:.: . .. :...::::::::::: :::
XP_005 MDNGMFSGFIMIKNLLLFCISMNLSSHFGFSQMPTSSVKDETNDNITIFTRILDGLLD
10 20 30 40 50
80 90 100 110 120 130
pF1KE4 GYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQTWHDERLKFDGPMKIL
:::::::::::. .:.:.::::::::::::::.:::::::::::.:.::::.: :::. :
XP_005 GYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQSWKDERLRFKGPMQRL
60 70 80 90 100 110
140 150 160 170 180 190
pF1KE4 PLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLPYTMRLTIHAECPMHLE
:::::::::::::::::::::::.::::::::::::: :.::: ::::::: :::::.::
XP_005 PLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLYTMRLTISAECPMQLE
120 130 140 150 160 170
200 210 220 230 240 250
pF1KE4 DFPMDVHACPLKFGSYAYTTAEVVYSWTLGKNKSVEVAQDGSRLNQYDLLGHVVGTEIIR
:::::.:::::::::::: ..:::: :: :..::: ::.:::::::: :.:..:::: :
XP_005 DFPMDAHACPLKFGSYAYPNSEVVYVWTNGSTKSVVVAEDGSRLNQYHLMGQTVGTENIS
180 190 200 210 220 230
260 270 280 290 300 310
pF1KE4 SSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVL
.:::::..::.:::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TSTGEYTIMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVL
240 250 260 270 280 290
320 330 340 350 360 370
pF1KE4 TMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRSWAWEGKKVPE
:::::::::::::::::::::::::::::::::::::::::::::::::.:::.:::. :
XP_005 TMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGWAWDGKKALE
300 310 320 330 340 350
380 390 400 410 420 430
pF1KE4 ALEMKKKTPAAPAKKTSTTFNIVGTTYPINLAKDTEFSTISKGAAPSASSTPTIIASPKA
: ..::: . .:....:. ..: :. :. .:...:. : . : :
XP_005 AAKIKKKREVI-LNKSTNAFTTGKMSHPPNIPKEQ---------TPAGTSNTTSV-SVKP
360 370 380 390 400
440 450 460 470 480 490
pF1KE4 TYVQDSPTETKTYNSVSKVDKISRIIFPVLFAIFNLVYWATYVNRESAIKGMIRKQ
. . : .. :::::.::.::.:::.:::::. :::::::::.::: .:::
XP_005 SEEKTSESK-KTYNSISKIDKMSRIVFPVLFGTFNLVYWATYLNREPVIKGAASPK
410 420 430 440 450 460
>>NP_001121116 (OMIM: 137160,611136,615744) gamma-aminob (456 aa)
initn: 2041 init1: 1849 opt: 1907 Z-score: 2167.7 bits: 410.5 E(85289): 5.3e-114
Smith-Waterman score: 2083; 74.5% identity (86.0% similar) in 436 aa overlap (54-486:29-450)
30 40 50 60 70 80
pF1KE4 PGTTGQGESRRQEPGDFVKQDIGGLSPKHAPDIPDDSTDNITIFTRILDRLLDGYDNRLR
:.. :. :: :.:::::::::::::::::
NP_001 MRKSPGLSDCLWAWILLLSTLTGRSYGQPSLQDELKDNTTVFTRILDRLLDGYDNRLR
10 20 30 40 50
90 100 110 120 130 140
pF1KE4 PGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQTWHDERLKFDGPMKILPLNNLLA
::::. ::::::::.::::::::: ::::::::::::.:.:::::: ::: .: ::::.:
NP_001 PGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVLRLNNLMA
60 70 80 90 100 110
150 160 170 180 190 200
pF1KE4 SKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLPYTMRLTIHAECPMHLEDFPMDVH
:::::::::::::::::::::: ::::::....::: ::::::..:::::::::::::.:
NP_001 SKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLEDFPMDAH
120 130 140 150 160 170
210 220 230 240 250 260
pF1KE4 ACPLKFGSYAYTTAEVVYSWTLGKNKSVEVAQDGSRLNQYDLLGHVVGTEIIRSSTGEYV
:::::::::::: ::::: :: .:: ::.::::::::::::..: . :..:::::::
NP_001 ACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLGQTVDSGIVQSSTGEYV
180 190 200 210 220 230
270 280 290 300 310 320
pF1KE4 VMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSI
240 250 260 270 280 290
330 340 350 360 370 380
pF1KE4 SARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRSWAWEGKKV-PEALEMKK
::::::::::::::::::::::::::::::::::::::::::..::.::.: :: :
NP_001 SARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKSVVPE----KP
300 310 320 330 340 350
390 400 410 420 430 440
pF1KE4 KTPAAPAKKTSTTFNIVGTTYPINLAK-DTEFSTISKGAAPSASSTPTIIASPKATYVQD
: : : ..:. ..:.: :::. : ..::.:.: :: :: . .
NP_001 KKVKDPLIKKNNTYAPTATSYTPNLARGDPGLATIAKSA--------TI--EPKEVKPET
360 370 380 390 400
450 460 470 480 490
pF1KE4 SPTETK-TYNSVSKVDKISRIIFPVLFAIFNLVYWATYVNRESAIKGMIRKQ
.: : : :.:::::.:..::: ::.::.::::::::::.::: .:
NP_001 KPPEPKKTFNSVSKIDRLSRIAFPLLFGIFNLVYWATYLNREPQLKAPTPHQ
410 420 430 440 450
>>NP_001121115 (OMIM: 137160,611136,615744) gamma-aminob (456 aa)
initn: 2041 init1: 1849 opt: 1907 Z-score: 2167.7 bits: 410.5 E(85289): 5.3e-114
Smith-Waterman score: 2083; 74.5% identity (86.0% similar) in 436 aa overlap (54-486:29-450)
30 40 50 60 70 80
pF1KE4 PGTTGQGESRRQEPGDFVKQDIGGLSPKHAPDIPDDSTDNITIFTRILDRLLDGYDNRLR
:.. :. :: :.:::::::::::::::::
NP_001 MRKSPGLSDCLWAWILLLSTLTGRSYGQPSLQDELKDNTTVFTRILDRLLDGYDNRLR
10 20 30 40 50
90 100 110 120 130 140
pF1KE4 PGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQTWHDERLKFDGPMKILPLNNLLA
::::. ::::::::.::::::::: ::::::::::::.:.:::::: ::: .: ::::.:
NP_001 PGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVLRLNNLMA
60 70 80 90 100 110
150 160 170 180 190 200
pF1KE4 SKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLPYTMRLTIHAECPMHLEDFPMDVH
:::::::::::::::::::::: ::::::....::: ::::::..:::::::::::::.:
NP_001 SKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLEDFPMDAH
120 130 140 150 160 170
210 220 230 240 250 260
pF1KE4 ACPLKFGSYAYTTAEVVYSWTLGKNKSVEVAQDGSRLNQYDLLGHVVGTEIIRSSTGEYV
:::::::::::: ::::: :: .:: ::.::::::::::::..: . :..:::::::
NP_001 ACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLGQTVDSGIVQSSTGEYV
180 190 200 210 220 230
270 280 290 300 310 320
pF1KE4 VMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSI
240 250 260 270 280 290
330 340 350 360 370 380
pF1KE4 SARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRSWAWEGKKV-PEALEMKK
::::::::::::::::::::::::::::::::::::::::::..::.::.: :: :
NP_001 SARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKSVVPE----KP
300 310 320 330 340 350
390 400 410 420 430 440
pF1KE4 KTPAAPAKKTSTTFNIVGTTYPINLAK-DTEFSTISKGAAPSASSTPTIIASPKATYVQD
: : : ..:. ..:.: :::. : ..::.:.: :: :: . .
NP_001 KKVKDPLIKKNNTYAPTATSYTPNLARGDPGLATIAKSA--------TI--EPKEVKPET
360 370 380 390 400
450 460 470 480 490
pF1KE4 SPTETK-TYNSVSKVDKISRIIFPVLFAIFNLVYWATYVNRESAIKGMIRKQ
.: : : :.:::::.:..::: ::.::.::::::::::.::: .:
NP_001 KPPEPKKTFNSVSKIDRLSRIAFPLLFGIFNLVYWATYLNREPQLKAPTPHQ
410 420 430 440 450
>>NP_001121117 (OMIM: 137160,611136,615744) gamma-aminob (456 aa)
initn: 2041 init1: 1849 opt: 1907 Z-score: 2167.7 bits: 410.5 E(85289): 5.3e-114
Smith-Waterman score: 2083; 74.5% identity (86.0% similar) in 436 aa overlap (54-486:29-450)
30 40 50 60 70 80
pF1KE4 PGTTGQGESRRQEPGDFVKQDIGGLSPKHAPDIPDDSTDNITIFTRILDRLLDGYDNRLR
:.. :. :: :.:::::::::::::::::
NP_001 MRKSPGLSDCLWAWILLLSTLTGRSYGQPSLQDELKDNTTVFTRILDRLLDGYDNRLR
10 20 30 40 50
90 100 110 120 130 140
pF1KE4 PGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQTWHDERLKFDGPMKILPLNNLLA
::::. ::::::::.::::::::: ::::::::::::.:.:::::: ::: .: ::::.:
NP_001 PGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVLRLNNLMA
60 70 80 90 100 110
150 160 170 180 190 200
pF1KE4 SKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLPYTMRLTIHAECPMHLEDFPMDVH
:::::::::::::::::::::: ::::::....::: ::::::..:::::::::::::.:
NP_001 SKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLEDFPMDAH
120 130 140 150 160 170
210 220 230 240 250 260
pF1KE4 ACPLKFGSYAYTTAEVVYSWTLGKNKSVEVAQDGSRLNQYDLLGHVVGTEIIRSSTGEYV
:::::::::::: ::::: :: .:: ::.::::::::::::..: . :..:::::::
NP_001 ACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLGQTVDSGIVQSSTGEYV
180 190 200 210 220 230
270 280 290 300 310 320
pF1KE4 VMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSI
240 250 260 270 280 290
330 340 350 360 370 380
pF1KE4 SARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRSWAWEGKKV-PEALEMKK
::::::::::::::::::::::::::::::::::::::::::..::.::.: :: :
NP_001 SARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKSVVPE----KP
300 310 320 330 340 350
390 400 410 420 430 440
pF1KE4 KTPAAPAKKTSTTFNIVGTTYPINLAK-DTEFSTISKGAAPSASSTPTIIASPKATYVQD
: : : ..:. ..:.: :::. : ..::.:.: :: :: . .
NP_001 KKVKDPLIKKNNTYAPTATSYTPNLARGDPGLATIAKSA--------TI--EPKEVKPET
360 370 380 390 400
450 460 470 480 490
pF1KE4 SPTETK-TYNSVSKVDKISRIIFPVLFAIFNLVYWATYVNRESAIKGMIRKQ
.: : : :.:::::.:..::: ::.::.::::::::::.::: .:
NP_001 KPPEPKKTFNSVSKIDRLSRIAFPLLFGIFNLVYWATYLNREPQLKAPTPHQ
410 420 430 440 450
>>NP_001121120 (OMIM: 137160,611136,615744) gamma-aminob (456 aa)
initn: 2041 init1: 1849 opt: 1907 Z-score: 2167.7 bits: 410.5 E(85289): 5.3e-114
Smith-Waterman score: 2083; 74.5% identity (86.0% similar) in 436 aa overlap (54-486:29-450)
30 40 50 60 70 80
pF1KE4 PGTTGQGESRRQEPGDFVKQDIGGLSPKHAPDIPDDSTDNITIFTRILDRLLDGYDNRLR
:.. :. :: :.:::::::::::::::::
NP_001 MRKSPGLSDCLWAWILLLSTLTGRSYGQPSLQDELKDNTTVFTRILDRLLDGYDNRLR
10 20 30 40 50
90 100 110 120 130 140
pF1KE4 PGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQTWHDERLKFDGPMKILPLNNLLA
::::. ::::::::.::::::::: ::::::::::::.:.:::::: ::: .: ::::.:
NP_001 PGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVLRLNNLMA
60 70 80 90 100 110
150 160 170 180 190 200
pF1KE4 SKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLPYTMRLTIHAECPMHLEDFPMDVH
:::::::::::::::::::::: ::::::....::: ::::::..:::::::::::::.:
NP_001 SKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLEDFPMDAH
120 130 140 150 160 170
210 220 230 240 250 260
pF1KE4 ACPLKFGSYAYTTAEVVYSWTLGKNKSVEVAQDGSRLNQYDLLGHVVGTEIIRSSTGEYV
:::::::::::: ::::: :: .:: ::.::::::::::::..: . :..:::::::
NP_001 ACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLGQTVDSGIVQSSTGEYV
180 190 200 210 220 230
270 280 290 300 310 320
pF1KE4 VMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSI
240 250 260 270 280 290
330 340 350 360 370 380
pF1KE4 SARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRSWAWEGKKV-PEALEMKK
::::::::::::::::::::::::::::::::::::::::::..::.::.: :: :
NP_001 SARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKSVVPE----KP
300 310 320 330 340 350
390 400 410 420 430 440
pF1KE4 KTPAAPAKKTSTTFNIVGTTYPINLAK-DTEFSTISKGAAPSASSTPTIIASPKATYVQD
: : : ..:. ..:.: :::. : ..::.:.: :: :: . .
NP_001 KKVKDPLIKKNNTYAPTATSYTPNLARGDPGLATIAKSA--------TI--EPKEVKPET
360 370 380 390 400
450 460 470 480 490
pF1KE4 SPTETK-TYNSVSKVDKISRIIFPVLFAIFNLVYWATYVNRESAIKGMIRKQ
.: : : :.:::::.:..::: ::.::.::::::::::.::: .:
NP_001 KPPEPKKTFNSVSKIDRLSRIAFPLLFGIFNLVYWATYLNREPQLKAPTPHQ
410 420 430 440 450
492 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 00:28:57 2016 done: Sun Nov 6 00:28:58 2016
Total Scan time: 5.270 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]