Result of FASTA (ccds) for
pFN21AE4470
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE4470, 492 aa
1>>>pF1KE4470 492 - 492 aa - 492 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.9393+/-0.00103; mu= 10.8790+/- 0.062
mean_var=130.6575+/-25.943, 0's: 0 Z-trim(109.4): 179 B-trim: 49 in 2/49
Lambda= 0.112204
statistics sampled from 10649 (10834) to 10649 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.692), E-opt: 0.2 (0.333), width: 16
Scan time: 2.650
The best scores are: opt bits E(32554)
CCDS33564.1 TMPRSS2 gene_id:7113|Hs108|chr21 ( 492) 3494 577.2 1.4e-164
CCDS54486.1 TMPRSS2 gene_id:7113|Hs108|chr21 ( 529) 3494 577.2 1.5e-164
CCDS58790.1 TMPRSS3 gene_id:64699|Hs108|chr21 ( 453) 1191 204.3 2.2e-52
CCDS13686.1 TMPRSS3 gene_id:64699|Hs108|chr21 ( 454) 1180 202.6 7.6e-52
CCDS55788.1 TMPRSS13 gene_id:84000|Hs108|chr11 ( 532) 1000 173.5 5.1e-43
CCDS41721.1 TMPRSS13 gene_id:84000|Hs108|chr11 ( 567) 995 172.7 9.4e-43
CCDS58185.1 TMPRSS13 gene_id:84000|Hs108|chr11 ( 563) 993 172.4 1.2e-42
CCDS44735.1 TMPRSS5 gene_id:80975|Hs108|chr11 ( 457) 907 158.4 1.5e-38
CCDS73392.1 TMPRSS5 gene_id:80975|Hs108|chr11 ( 448) 905 158.0 1.9e-38
CCDS73391.1 TMPRSS5 gene_id:80975|Hs108|chr11 ( 413) 893 156.1 6.8e-38
CCDS13571.1 TMPRSS15 gene_id:5651|Hs108|chr21 (1019) 899 157.3 7.1e-38
CCDS75122.1 CORIN gene_id:10699|Hs108|chr4 ( 938) 824 145.2 3e-34
CCDS3477.1 CORIN gene_id:10699|Hs108|chr4 (1042) 824 145.2 3.2e-34
CCDS53717.1 TMPRSS4 gene_id:56649|Hs108|chr11 ( 397) 810 142.6 7.4e-34
CCDS53716.1 TMPRSS4 gene_id:56649|Hs108|chr11 ( 435) 810 142.7 7.9e-34
CCDS31684.1 TMPRSS4 gene_id:56649|Hs108|chr11 ( 437) 810 142.7 7.9e-34
CCDS44743.1 TMPRSS4 gene_id:56649|Hs108|chr11 ( 432) 806 142.0 1.2e-33
CCDS34120.1 KLKB1 gene_id:3818|Hs108|chr4 ( 638) 767 135.8 1.3e-31
CCDS76482.1 TMPRSS4 gene_id:56649|Hs108|chr11 ( 290) 752 133.1 3.9e-31
CCDS32993.1 HPN gene_id:3249|Hs108|chr19 ( 417) 747 132.4 9e-31
CCDS3520.1 TMPRSS11F gene_id:389208|Hs108|chr4 ( 438) 722 128.4 1.5e-29
CCDS8487.1 ST14 gene_id:6768|Hs108|chr11 ( 855) 717 127.8 4.6e-29
CCDS3518.1 TMPRSS11D gene_id:9407|Hs108|chr4 ( 418) 711 126.6 5.1e-29
CCDS3847.1 F11 gene_id:2160|Hs108|chr4 ( 625) 712 126.9 6.2e-29
CCDS74856.1 TMPRSS6 gene_id:164656|Hs108|chr22 ( 802) 686 122.8 1.4e-27
CCDS13941.1 TMPRSS6 gene_id:164656|Hs108|chr22 ( 811) 686 122.8 1.4e-27
CCDS33993.1 TMPRSS11E gene_id:28983|Hs108|chr4 ( 423) 677 121.1 2.3e-27
CCDS3521.1 TMPRSS11B gene_id:132724|Hs108|chr4 ( 416) 676 121.0 2.6e-27
CCDS42939.1 TMPRSS3 gene_id:64699|Hs108|chr21 ( 344) 670 119.9 4.4e-27
CCDS12088.1 TMPRSS9 gene_id:360200|Hs108|chr19 (1059) 677 121.4 4.8e-27
CCDS43129.2 TMPRSS7 gene_id:344805|Hs108|chr3 ( 717) 655 117.7 4.2e-26
CCDS10430.1 TPSG1 gene_id:25823|Hs108|chr16 ( 321) 642 115.4 9.6e-26
CCDS47065.1 TMPRSS11A gene_id:339967|Hs108|chr4 ( 418) 642 115.5 1.2e-25
CCDS3519.1 TMPRSS11A gene_id:339967|Hs108|chr4 ( 421) 642 115.5 1.2e-25
CCDS74669.1 PRSS56 gene_id:646960|Hs108|chr2 ( 603) 638 114.9 2.5e-25
CCDS44881.1 TMPRSS12 gene_id:283471|Hs108|chr12 ( 348) 623 112.3 8.6e-25
CCDS45469.1 PRSS8 gene_id:5652|Hs108|chr16 ( 343) 622 112.2 9.5e-25
CCDS10481.1 PRSS22 gene_id:64063|Hs108|chr16 ( 317) 617 111.3 1.6e-24
CCDS1563.1 PRSS38 gene_id:339501|Hs108|chr1 ( 326) 614 110.8 2.2e-24
CCDS47145.1 PRSS48 gene_id:345062|Hs108|chr4 ( 328) 614 110.8 2.3e-24
CCDS5279.1 PLG gene_id:5340|Hs108|chr6 ( 810) 613 111.0 5.1e-24
CCDS10431.1 TPSAB1 gene_id:7177|Hs108|chr16 ( 275) 590 106.9 2.9e-23
CCDS157.1 CELA2A gene_id:63036|Hs108|chr1 ( 269) 583 105.8 6.3e-23
CCDS32490.1 CTRB1 gene_id:1504|Hs108|chr16 ( 263) 580 105.3 8.6e-23
CCDS10852.1 CTRL gene_id:1506|Hs108|chr16 ( 264) 575 104.5 1.5e-22
CCDS14101.1 ACR gene_id:49|Hs108|chr22 ( 421) 574 104.4 2.4e-22
CCDS32489.1 CTRB2 gene_id:440387|Hs108|chr16 ( 263) 564 102.7 5.2e-22
CCDS73390.1 TMPRSS5 gene_id:80975|Hs108|chr11 ( 344) 563 102.6 7.2e-22
CCDS73393.1 TMPRSS5 gene_id:80975|Hs108|chr11 ( 388) 563 102.6 7.9e-22
CCDS3369.1 HGFAC gene_id:3083|Hs108|chr4 ( 655) 564 103.0 1.1e-21
>>CCDS33564.1 TMPRSS2 gene_id:7113|Hs108|chr21 (492 aa)
initn: 3494 init1: 3494 opt: 3494 Z-score: 3068.2 bits: 577.2 E(32554): 1.4e-164
Smith-Waterman score: 3494; 100.0% identity (100.0% similar) in 492 aa overlap (1-492:1-492)
10 20 30 40 50 60
pF1KE4 MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 SNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIEC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 SNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIEC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 DSSGTCINPSNWCDGVSHCPGGEDENRCVRLYGPNFILQVYSSQRKSWHPVCQDDWNENY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 DSSGTCINPSNWCDGVSHCPGGEDENRCVRLYGPNFILQVYSSQRKSWHPVCQDDWNENY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 GRAACRDMGYKNNFYSSQGIVDDSGSTSFMKLNTSAGNVDIYKKLYHSDACSSKAVVSLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 GRAACRDMGYKNNFYSSQGIVDDSGSTSFMKLNTSAGNVDIYKKLYHSDACSSKAVVSLR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 CIACGVNLNSSRQSRIVGGESALPGAWPWQVSLHVQNVHVCGGSIITPEWIVTAAHCVEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 CIACGVNLNSSRQSRIVGGESALPGAWPWQVSLHVQNVHVCGGSIITPEWIVTAAHCVEK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 PLNNPWHWTAFAGILRQSFMFYGAGYQVEKVISHPNYDSKTKNNDIALMKLQKPLTFNDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 PLNNPWHWTAFAGILRQSFMFYGAGYQVEKVISHPNYDSKTKNNDIALMKLQKPLTFNDL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 VKPVCLPNPGMMLQPEQLCWISGWGATEEKGKTSEVLNAAKVLLIETQRCNSRYVYDNLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 VKPVCLPNPGMMLQPEQLCWISGWGATEEKGKTSEVLNAAKVLLIETQRCNSRYVYDNLI
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE4 TPAMICAGFLQGNVDSCQGDSGGPLVTSKNNIWWLIGDTSWGSGCAKAYRPGVYGNVMVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 TPAMICAGFLQGNVDSCQGDSGGPLVTSKNNIWWLIGDTSWGSGCAKAYRPGVYGNVMVF
430 440 450 460 470 480
490
pF1KE4 TDWIYRQMRADG
::::::::::::
CCDS33 TDWIYRQMRADG
490
>>CCDS54486.1 TMPRSS2 gene_id:7113|Hs108|chr21 (529 aa)
initn: 3494 init1: 3494 opt: 3494 Z-score: 3067.7 bits: 577.2 E(32554): 1.5e-164
Smith-Waterman score: 3494; 100.0% identity (100.0% similar) in 492 aa overlap (1-492:38-529)
10 20 30
pF1KE4 MALNSGSPPAIGPYYENHGYQPENPYPAQP
::::::::::::::::::::::::::::::
CCDS54 GESGCEERGAAGHIEHSRYLSLLDAVDNSKMALNSGSPPAIGPYYENHGYQPENPYPAQP
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE4 TVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 TVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLT
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE4 LGTFLVGAALAAGLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 LGTFLVGAALAAGLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVR
130 140 150 160 170 180
160 170 180 190 200 210
pF1KE4 LYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKNNFYSSQGIVDDSGSTSFM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 LYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKNNFYSSQGIVDDSGSTSFM
190 200 210 220 230 240
220 230 240 250 260 270
pF1KE4 KLNTSAGNVDIYKKLYHSDACSSKAVVSLRCIACGVNLNSSRQSRIVGGESALPGAWPWQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 KLNTSAGNVDIYKKLYHSDACSSKAVVSLRCIACGVNLNSSRQSRIVGGESALPGAWPWQ
250 260 270 280 290 300
280 290 300 310 320 330
pF1KE4 VSLHVQNVHVCGGSIITPEWIVTAAHCVEKPLNNPWHWTAFAGILRQSFMFYGAGYQVEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 VSLHVQNVHVCGGSIITPEWIVTAAHCVEKPLNNPWHWTAFAGILRQSFMFYGAGYQVEK
310 320 330 340 350 360
340 350 360 370 380 390
pF1KE4 VISHPNYDSKTKNNDIALMKLQKPLTFNDLVKPVCLPNPGMMLQPEQLCWISGWGATEEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 VISHPNYDSKTKNNDIALMKLQKPLTFNDLVKPVCLPNPGMMLQPEQLCWISGWGATEEK
370 380 390 400 410 420
400 410 420 430 440 450
pF1KE4 GKTSEVLNAAKVLLIETQRCNSRYVYDNLITPAMICAGFLQGNVDSCQGDSGGPLVTSKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 GKTSEVLNAAKVLLIETQRCNSRYVYDNLITPAMICAGFLQGNVDSCQGDSGGPLVTSKN
430 440 450 460 470 480
460 470 480 490
pF1KE4 NIWWLIGDTSWGSGCAKAYRPGVYGNVMVFTDWIYRQMRADG
::::::::::::::::::::::::::::::::::::::::::
CCDS54 NIWWLIGDTSWGSGCAKAYRPGVYGNVMVFTDWIYRQMRADG
490 500 510 520
>>CCDS58790.1 TMPRSS3 gene_id:64699|Hs108|chr21 (453 aa)
initn: 1037 init1: 648 opt: 1191 Z-score: 1053.9 bits: 204.3 E(32554): 2.2e-52
Smith-Waterman score: 1191; 46.0% identity (68.4% similar) in 411 aa overlap (89-491:52-450)
60 70 80 90 100 110
pF1KE4 QASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGI
...: . . ::: :: .: ::..
CCDS58 DDLKISPVAPDADAVAAQILSLLPLKFFPIIVIGIIALILALAIGLGIHF---DCSGK-Y
30 40 50 60 70
120 130 140 150 160 170
pF1KE4 ECDSSGTCINPSNWCDGVSHCPGGEDENRCVRLYGPNFILQVYSSQRKSWHPVCQDDWNE
.: :: ::. ::::: : :::: ::::. : : .:::... ::. .:.:::.
CCDS58 RCRSSFKCIELIARCDGVSDCKDGEDEYRCVRVGGQNAVLQVFTAA--SWKTMCSDDWKG
80 90 100 110 120 130
180 190 200 210 220 230
pF1KE4 NYGRAACRDMGYKNNFYSSQGIVDDSGSTSFMKLNTSAGNV---DIYKKLYHS----DAC
.:. .:: ..:. . . ::... .: .: . .: .. : :.:: ..:
CCDS58 HYANVACAQLGFPS-YVSSDNLRVSSLEGQFREEFVSIDHLLPDDKVTALHHSVYVREGC
140 150 160 170 180 190
240 250 260 270 280 290
pF1KE4 SSKAVVSLRCIACGVNLNSSRQSRIVGGESALPGAWPWQVSLHVQNVHVCGGSIITPEWI
.: ::.:.: ::: . : ::::::. .: . ::::.::. :. :.::::.::: ::
CCDS58 ASGHVVTLQCTACGHRRGYS--SRIVGGNMSLLSQWPWQASLQFQGYHLCGGSVITPLWI
200 210 220 230 240 250
300 310 320 330 340 350
pF1KE4 VTAAHCVEKPLNNPWHWTAFAGILRQSFMFYGA-GYQVEKVISHPNYDSKTKNNDIALMK
.:::::: : : :: .:.. :.. : .. :::.. : .: : .:::::::
CCDS58 ITAAHCVYD-LYLPKSWTIQVGLV--SLLDNPAPSHLVEKIVYHSKYKPKRLGNDIALMK
260 270 280 290 300
360 370 380 390 400 410
pF1KE4 LQKPLTFNDLVKPVCLPNPGMMLQPEQLCWISGWGATEEKGKTSEVLNAAKVLLIETQRC
: :::::....:::::: . ..:: :::::::. : .: ::: : : :: .. :
CCDS58 LAGPLTFNEMIQPVCLPNSEENFPDGKVCWTSGWGATEDGGDASPVLNHAAVPLISNKIC
310 320 330 340 350 360
420 430 440 450 460 470
pF1KE4 NSRYVYDNLITPAMICAGFLQGNVDSCQGDSGGPLVTSKNNIWWLIGDTSWGSGCAKAYR
: : :: ..:.:.:.:::.: :.::::::::::::: .. .: :.: ::.: :::.. .
CCDS58 NHRDVYGGIISPSMLCAGYLTGGVDSCQGDSGGPLVCQERRLWKLVGATSFGIGCAEVNK
370 380 390 400 410 420
480 490
pF1KE4 PGVYGNVMVFTDWIYRQMRADG
:::: : : :::..::. :
CCDS58 PGVYTRVTSFLDWIHEQMERDLKT
430 440 450
>>CCDS13686.1 TMPRSS3 gene_id:64699|Hs108|chr21 (454 aa)
initn: 1014 init1: 386 opt: 1180 Z-score: 1044.2 bits: 202.6 E(32554): 7.6e-52
Smith-Waterman score: 1180; 45.9% identity (68.2% similar) in 412 aa overlap (89-491:52-451)
60 70 80 90 100 110
pF1KE4 QASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGI
...: . . ::: :: .: ::..
CCDS13 DDLKISPVAPDADAVAAQILSLLPLKFFPIIVIGIIALILALAIGLGIHF---DCSGK-Y
30 40 50 60 70
120 130 140 150 160 170
pF1KE4 ECDSSGTCINPSNWCDGVSHCPGGEDENRCVRLYGPNFILQVYSSQRKSWHPVCQDDWNE
.: :: ::. ::::: : :::: ::::. : : .:::... ::. .:.:::.
CCDS13 RCRSSFKCIELIARCDGVSDCKDGEDEYRCVRVGGQNAVLQVFTAA--SWKTMCSDDWKG
80 90 100 110 120 130
180 190 200 210 220 230
pF1KE4 NYGRAACRDMGYKNNFYSSQGIVDDSGSTSFMKLNTSAGNV---DIYKKLYHS----DAC
.:. .:: ..:. . . ::... .: .: . .: .. : :.:: ..:
CCDS13 HYANVACAQLGFPS-YVSSDNLRVSSLEGQFREEFVSIDHLLPDDKVTALHHSVYVREGC
140 150 160 170 180 190
240 250 260 270 280 290
pF1KE4 SSKAVVSLRCIACGVNLNSSRQSRIVGGESALPGAWPWQVSLHVQNVHVCGGSIITPEWI
.: ::.:.: ::: . : ::::::. .: . ::::.::. :. :.::::.::: ::
CCDS13 ASGHVVTLQCTACGHRRGYS--SRIVGGNMSLLSQWPWQASLQFQGYHLCGGSVITPLWI
200 210 220 230 240 250
300 310 320 330 340 350
pF1KE4 VTAAHCVEKPLNNPWHWTAFAGILRQSFMFYGA-GYQVEKVISHPNYDSKTKNNDIALMK
.:::::: : : :: .:.. :.. : .. :::.. : .: : .:::::::
CCDS13 ITAAHCVYD-LYLPKSWTIQVGLV--SLLDNPAPSHLVEKIVYHSKYKPKRLGNDIALMK
260 270 280 290 300
360 370 380 390 400
pF1KE4 LQKPLTFNDLVKPVCLPNPGMMLQPEQLCWISGWGATEE-KGKTSEVLNAAKVLLIETQR
: :::::....:::::: . ..:: :::::::. : .: ::: : : :: ..
CCDS13 LAGPLTFNEMIQPVCLPNSEENFPDGKVCWTSGWGATEDGAGDASPVLNHAAVPLISNKI
310 320 330 340 350 360
410 420 430 440 450 460
pF1KE4 CNSRYVYDNLITPAMICAGFLQGNVDSCQGDSGGPLVTSKNNIWWLIGDTSWGSGCAKAY
:: : :: ..:.:.:.:::.: :.::::::::::::: .. .: :.: ::.: :::..
CCDS13 CNHRDVYGGIISPSMLCAGYLTGGVDSCQGDSGGPLVCQERRLWKLVGATSFGIGCAEVN
370 380 390 400 410 420
470 480 490
pF1KE4 RPGVYGNVMVFTDWIYRQMRADG
.:::: : : :::..::. :
CCDS13 KPGVYTRVTSFLDWIHEQMERDLKT
430 440 450
>>CCDS55788.1 TMPRSS13 gene_id:84000|Hs108|chr11 (532 aa)
initn: 866 init1: 497 opt: 1000 Z-score: 885.8 bits: 173.5 E(32554): 5.1e-43
Smith-Waterman score: 1006; 34.4% identity (62.1% similar) in 506 aa overlap (7-491:35-526)
10 20 30
pF1KE4 MALNSGSPPAIGPYYENH-GYQPENPYPAQ--PTVV
:: .: . : : ::: :. .
CCDS55 SHGNASPARTPSAGASPAQASPAGTPPGRASPAQASPAQASPAGTPPGRASPAQASPAGT
10 20 30 40 50 60
40 50 60 70 80
pF1KE4 P----TVYEVHPAQYYPSPV-PQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCIT
: . .. ::: :. . : : .:.. : . .. :..: :: :. : .
CCDS55 PPGRASPGRASPAQASPAQASPARASPALASLSRSSSGRSSSARSASVTTSPTRVYLVRA
70 80 90 100 110 120
90 100 110 120 130 140
pF1KE4 LTLGTFLV--GAALAAGLLWKFMGSKCS----NSGIEC-DSSGTCINPSNWCDGVSHCPG
.:. . . : .: : . ..::. .. .: . . :::: :
CCDS55 TPVGAVPIRSSPARSAPATRATRESPVQFWQGHTGIRYKEQRESCPKHAVRCDGVVDCKL
130 140 150 160 170 180
150 160 170 180 190 200
pF1KE4 GEDENRCVRLYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKNNFYSSQGIV
:: :::. . .:..::.. ..: :.:...::..:.. .:...:... ...
CCDS55 KSDELGCVRFDWDKSLLKIYSGSSHQWLPICSSNWNDSYSEKTCQQLGFESAHRTTEVAH
190 200 210 220 230 240
210 220 230 240 250 260
pF1KE4 DD-SGSTSFMKLNTSAGNVDIYKKLYHSDACSSKAVVSLRCIACGVNLNSSRQSRIVGGE
: ..: :... :.. : ..:..:. : :. .::.: ::. ..: ::::
CCDS55 RDFANSFSILRYNST-----IQESLHRSE-CPSQRYISLQCSHCGLRAMTGR---IVGGA
250 260 270 280 290
270 280 290 300 310
pF1KE4 SALPGAWPWQVSLHVQNVHVCGGSIITPEWIVTAAHCV----EKPLNNPWHWTAFAGILR
: . :::::::: ..:.:::..: .:..::::: :: :.. : ..::
CCDS55 LASDSKWPWQVSLHFGTTHICGGTLIDAQWVLTAAHCFFVTREKVLEG---WKVYAG--T
300 310 320 330 340 350
320 330 340 350 360 370
pF1KE4 QSFMFYGAGYQVEKVISHPNYDSKTKNNDIALMKLQKPLTFNDLVKPVCLPNPGMMLQPE
... . .. ..: . :: .. . :::::.:.::::.. ..:.::: :. .. .
CCDS55 SNLHQLPEAASIAEIIINSNYTDEEDDYDIALMRLSKPLTLSAHIHPACLPMHGQTFSLN
360 370 380 390 400 410
380 390 400 410 420 430
pF1KE4 QLCWISGWGATEEKG-KTSEVLNAAKVLLIETQRCNSRYVYDNLITPAMICAGFLQGNVD
. :::.:.: :.: ::: : ..: ::. ..::. :::. .:: :.::: :.:. :
CCDS55 ETCWITGFGKTRETDDKTSPFLREVQVNLIDFKKCNDYLVYDSYLTPRMMCAGDLRGGRD
420 430 440 450 460 470
440 450 460 470 480 490
pF1KE4 SCQGDSGGPLVTSKNNIWWLIGDTSWGSGCAKAYRPGVYGNVMVFTDWIYRQMRADG
::::::::::: .:: :.: : ::::.::.. .:::: .: ::: .:...
CCDS55 SCQGDSGGPLVCEQNNRWYLAGVTSWGTGCGQRNKPGVYTKVTEVLPWIYSKMESEVRFR
480 490 500 510 520 530
CCDS55 KS
>>CCDS41721.1 TMPRSS13 gene_id:84000|Hs108|chr11 (567 aa)
initn: 882 init1: 497 opt: 995 Z-score: 881.0 bits: 172.7 E(32554): 9.4e-43
Smith-Waterman score: 1009; 35.4% identity (63.4% similar) in 492 aa overlap (9-491:91-561)
10 20 30
pF1KE4 MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPT-VY
::.. .. . . . :. :. :: ::
CCDS41 PAGTPPGRASPGRASPAQASPAQASPARASPALASLSRSSSGRSSSARSASVTTSPTRVY
70 80 90 100 110 120
40 50 60 70 80 90
pF1KE4 EVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTL-GTFLV
:. .:: : : :.. . .:: :: . : . : : : :.
CCDS41 LVR-----ATPVGAVPIRSSPARSAPATRATRESP-GTSLPKFTWREGQKQLPLIGCVLL
130 140 150 160 170
100 110 120 130 140 150
pF1KE4 GAALAAGLLWKFMGSKCSNSGIEC-DSSGTCINPSNWCDGVSHCPGGEDENRCVRLYGPN
::...:. :. . ...::. .. .: . . :::: : :: :::. .
CCDS41 LIALVVSLIILFQFWQ-GHTGIRYKEQRESCPKHAVRCDGVVDCKLKSDELGCVRFDWDK
180 190 200 210 220 230
160 170 180 190 200 210
pF1KE4 FILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKNNFYSSQGIVDD-SGSTSFMKLNT
.:..::.. ..: :.:...::..:.. .:...:... ... : ..: :... :.
CCDS41 SLLKIYSGSSHQWLPICSSNWNDSYSEKTCQQLGFESAHRTTEVAHRDFANSFSILRYNS
240 250 260 270 280 290
220 230 240 250 260 270
pF1KE4 SAGNVDIYKKLYHSDACSSKAVVSLRCIACGVNLNSSRQSRIVGGESALPGAWPWQVSLH
. : ..:..:. : :. .::.: ::. . .::::: : . ::::::::
CCDS41 T-----IQESLHRSE-CPSQRYISLQCSHCGL---RAMTGRIVGGALASDSKWPWQVSLH
300 310 320 330 340
280 290 300 310 320 330
pF1KE4 VQNVHVCGGSIITPEWIVTAAHCV----EKPLNNPWHWTAFAGILRQSFMFYGAGYQVEK
..:.:::..: .:..::::: :: :.. : ..:: . .:. . .
CCDS41 FGTTHICGGTLIDAQWVLTAAHCFFVTREKVLEG---WKVYAGTSNLHQLPEAAS--IAE
350 360 370 380 390
340 350 360 370 380 390
pF1KE4 VISHPNYDSKTKNNDIALMKLQKPLTFNDLVKPVCLPNPGMMLQPEQLCWISGWGATEEK
.: . :: .. . :::::.:.::::.. ..:.::: :. .. .. :::.:.: :.:
CCDS41 IIINSNYTDEEDDYDIALMRLSKPLTLSAHIHPACLPMHGQTFSLNETCWITGFGKTRET
400 410 420 430 440 450
400 410 420 430 440
pF1KE4 G-KTSEVLNAAKVLLIETQRCNSRYVYDNLITPAMICAGFLQGNVDSCQGDSGGPLVTSK
::: : ..: ::. ..::. :::. .:: :.::: :.:. :::::::::::: .
CCDS41 DDKTSPFLREVQVNLIDFKKCNDYLVYDSYLTPRMMCAGDLRGGRDSCQGDSGGPLVCEQ
460 470 480 490 500 510
450 460 470 480 490
pF1KE4 NNIWWLIGDTSWGSGCAKAYRPGVYGNVMVFTDWIYRQMRADG
:: :.: : ::::.::.. .:::: .: ::: .:...
CCDS41 NNRWYLAGVTSWGTGCGQRNKPGVYTKVTEVLPWIYSKMESEVRFRKS
520 530 540 550 560
>>CCDS58185.1 TMPRSS13 gene_id:84000|Hs108|chr11 (563 aa)
initn: 880 init1: 495 opt: 993 Z-score: 879.3 bits: 172.4 E(32554): 1.2e-42
Smith-Waterman score: 1007; 35.4% identity (63.3% similar) in 491 aa overlap (9-490:91-560)
10 20 30
pF1KE4 MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPT-VY
::.. .. . . . :. :. :: ::
CCDS58 PAGTPPGRASPGRASPAQASPAQASPARASPALASLSRSSSGRSSSARSASVTTSPTRVY
70 80 90 100 110 120
40 50 60 70 80 90
pF1KE4 EVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTL-GTFLV
:. .:: : : :.. . .:: :: . : . : : : :.
CCDS58 LVR-----ATPVGAVPIRSSPARSAPATRATRESP-GTSLPKFTWREGQKQLPLIGCVLL
130 140 150 160 170
100 110 120 130 140 150
pF1KE4 GAALAAGLLWKFMGSKCSNSGIEC-DSSGTCINPSNWCDGVSHCPGGEDENRCVRLYGPN
::...:. :. . ...::. .. .: . . :::: : :: :::. .
CCDS58 LIALVVSLIILFQFWQ-GHTGIRYKEQRESCPKHAVRCDGVVDCKLKSDELGCVRFDWDK
180 190 200 210 220 230
160 170 180 190 200 210
pF1KE4 FILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKNNFYSSQGIVDD-SGSTSFMKLNT
.:..::.. ..: :.:...::..:.. .:...:... ... : ..: :... :.
CCDS58 SLLKIYSGSSHQWLPICSSNWNDSYSEKTCQQLGFESAHRTTEVAHRDFANSFSILRYNS
240 250 260 270 280 290
220 230 240 250 260 270
pF1KE4 SAGNVDIYKKLYHSDACSSKAVVSLRCIACGVNLNSSRQSRIVGGESALPGAWPWQVSLH
. : ..:..:. : :. .::.: ::. . .::::: : . ::::::::
CCDS58 T-----IQESLHRSE-CPSQRYISLQCSHCGL---RAMTGRIVGGALASDSKWPWQVSLH
300 310 320 330 340
280 290 300 310 320 330
pF1KE4 VQNVHVCGGSIITPEWIVTAAHCV----EKPLNNPWHWTAFAGILRQSFMFYGAGYQVEK
..:.:::..: .:..::::: :: :.. : ..:: . .:. . .
CCDS58 FGTTHICGGTLIDAQWVLTAAHCFFVTREKVLEG---WKVYAGTSNLHQLPEAAS--IAE
350 360 370 380 390
340 350 360 370 380 390
pF1KE4 VISHPNYDSKTKNNDIALMKLQKPLTFNDLVKPVCLPNPGMMLQPEQLCWISGWGATEEK
.: . :: .. . :::::.:.::::.. ..:.::: :. .. .. :::.:.: :.:
CCDS58 IIINSNYTDEEDDYDIALMRLSKPLTLSAHIHPACLPMHGQTFSLNETCWITGFGKTRET
400 410 420 430 440 450
400 410 420 430 440
pF1KE4 G-KTSEVLNAAKVLLIETQRCNSRYVYDNLITPAMICAGFLQGNVDSCQGDSGGPLVTSK
::: : ..: ::. ..::. :::. .:: :.::: :.:. :::::::::::: .
CCDS58 DDKTSPFLREVQVNLIDFKKCNDYLVYDSYLTPRMMCAGDLRGGRDSCQGDSGGPLVCEQ
460 470 480 490 500 510
450 460 470 480 490
pF1KE4 NNIWWLIGDTSWGSGCAKAYRPGVYGNVMVFTDWIYRQMRADG
:: :.: : ::::.::.. .:::: .: ::: .:..
CCDS58 NNRWYLAGVTSWGTGCGQRNKPGVYTKVTEVLPWIYSKMESSAG
520 530 540 550 560
>>CCDS44735.1 TMPRSS5 gene_id:80975|Hs108|chr11 (457 aa)
initn: 813 init1: 336 opt: 907 Z-score: 805.4 bits: 158.4 E(32554): 1.5e-38
Smith-Waterman score: 907; 35.4% identity (62.3% similar) in 427 aa overlap (68-485:32-449)
40 50 60 70 80 90
pF1KE4 EVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVG
: . : .:: . ... . .:: .:.:
CCDS44 SLMLDDQPPMEAQYAEEGPGPGIFRAEPGDQQHPISQAVCWRSMRRGCAVLGALG-LLAG
10 20 30 40 50 60
100 110 120 130 140 150
pF1KE4 AALAAGLLWKFMGSKCSN--SGIECDSSGT--CINPSNWCDGVSHCPGGEDENRCVRLYG
:.... :: .. :. :: : : : . : . : .. :. .
CCDS44 AGVGSWLLVLYLCPAASQPISGTLQDEEITLSCSEASAEEALLPALP----KTVSFRINS
70 80 90 100 110
160 170 180 190 200 210
pF1KE4 PNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGY-KNNFYSSQGIVDDSGSTS--FM
.:.:.. .. : ::.. :. : : ..:. . . ... ...: . ..: :
CCDS44 EDFLLEAQVRDQPRWLLVCHEGWSPALGLQICWSLGHLRLTHHKGVNLTDIKLNSSQEFA
120 130 140 150 160 170
220 230 240 250 260 270
pF1KE4 KLNTSAGNVDIYKKLYHSDACSSKAVVSLRCIACGVNLNSSRQSRIVGGESALPGAWPWQ
.:. :. . . . :.: :::::: ::. ::::::.:. :: ::::
CCDS44 QLSPRLGGF-LEEAWQPRNNCTSGQVVSLRCSECGA---RPLASRIVGGQSVAPGRWPWQ
180 190 200 210 220 230
280 290 300 310 320
pF1KE4 VSLHVQNVHVCGGSIITPEWIVTAAHCVEK-PLNNPWHWTAFAGILRQSFMFYGAGYQVE
.:. . :.::::...:.:.::::::... : : . ::.. .: . : ::
CCDS44 ASVALGFRHTCGGSVLAPRWVVTAAHCMHSFRLARLSSWRVHAGLVSHSAVRPHQGALVE
240 250 260 270 280 290
330 340 350 360 370 380
pF1KE4 KVISHPNYDSKTKNNDIALMKLQKPLTFNDLVKPVCLPNPGMMLQPEQLCWISGWGATEE
..: :: :...... :.::..:: :.:.: : :::: . . . ::.:::: :.
CCDS44 RIIPHPLYSAQNHDYDVALLRLQTALNFSDTVGAVCLPAKEQHFPKGSRCWVSGWGHTHP
300 310 320 330 340 350
390 400 410 420 430 440
pF1KE4 KGK-TSEVLNAAKVLLIETQRCNSRYVYDNLITPAMICAGFLQGNVDSCQGDSGGPLVTS
. .:..:. . : :. :: ::: ::.. .:: :.:::.:.: .:.::::::::::
CCDS44 SHTYSSDMLQDTVVPLFSTQLCNSSCVYSGALTPRMLCAGYLDGRADACQGDSGGPLVCP
360 370 380 390 400 410
450 460 470 480 490
pF1KE4 KNNIWWLIGDTSWGSGCAKAYRPGVYGNVMVFTDWIYRQMRADG
.. : :.: .::: :::. .::::..: : :::.
CCDS44 DGDTWRLVGVVSWGRGCAEPNHPGVYAKVAEFLDWIHDTAQDSLL
420 430 440 450
>>CCDS73392.1 TMPRSS5 gene_id:80975|Hs108|chr11 (448 aa)
initn: 813 init1: 336 opt: 905 Z-score: 803.7 bits: 158.0 E(32554): 1.9e-38
Smith-Waterman score: 905; 35.5% identity (62.6% similar) in 422 aa overlap (73-485:28-440)
50 60 70 80 90 100
pF1KE4 QYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAA
: .:: . ... . .:: .:.::....
CCDS73 MTGWGQWRAIILHSPDPPWGQPHMIDVSQAVCWRSMRRGCAVLGALG-LLAGAGVGS
10 20 30 40 50
110 120 130 140 150
pF1KE4 GLLWKFMGSKCSN--SGIECDSSGT--CINPSNWCDGVSHCPGGEDENRCVRLYGPNFIL
:: .. :. :: : : : . : . : .. :. . .:.:
CCDS73 WLLVLYLCPAASQPISGTLQDEEITLSCSEASAEEALLPALP----KTVSFRINSEDFLL
60 70 80 90 100 110
160 170 180 190 200 210
pF1KE4 QVYSSQRKSWHPVCQDDWNENYGRAACRDMGY-KNNFYSSQGIVDDSGSTS--FMKLNTS
.. .. : ::.. :. : : ..:. . . ... ...: . ..: : .:.
CCDS73 EAQVRDQPRWLLVCHEGWSPALGLQICWSLGHLRLTHHKGVNLTDIKLNSSQEFAQLSPR
120 130 140 150 160 170
220 230 240 250 260 270
pF1KE4 AGNVDIYKKLYHSDACSSKAVVSLRCIACGVNLNSSRQSRIVGGESALPGAWPWQVSLHV
:. . . . :.: :::::: ::. ::::::.:. :: ::::.:. .
CCDS73 LGGF-LEEAWQPRNNCTSGQVVSLRCSECGAR---PLASRIVGGQSVAPGRWPWQASVAL
180 190 200 210 220
280 290 300 310 320 330
pF1KE4 QNVHVCGGSIITPEWIVTAAHCVEK-PLNNPWHWTAFAGILRQSFMFYGAGYQVEKVISH
:.::::...:.:.::::::... : : . ::.. .: . : ::..: :
CCDS73 GFRHTCGGSVLAPRWVVTAAHCMHSFRLARLSSWRVHAGLVSHSAVRPHQGALVERIIPH
230 240 250 260 270 280
340 350 360 370 380 390
pF1KE4 PNYDSKTKNNDIALMKLQKPLTFNDLVKPVCLPNPGMMLQPEQLCWISGWGATEEKGK-T
: :...... :.::..:: :.:.: : :::: . . . ::.:::: :. . .
CCDS73 PLYSAQNHDYDVALLRLQTALNFSDTVGAVCLPAKEQHFPKGSRCWVSGWGHTHPSHTYS
290 300 310 320 330 340
400 410 420 430 440 450
pF1KE4 SEVLNAAKVLLIETQRCNSRYVYDNLITPAMICAGFLQGNVDSCQGDSGGPLVTSKNNIW
:..:. . : :. :: ::: ::.. .:: :.:::.:.: .:.:::::::::: .. :
CCDS73 SDMLQDTVVPLFSTQLCNSSCVYSGALTPRMLCAGYLDGRADACQGDSGGPLVCPDGDTW
350 360 370 380 390 400
460 470 480 490
pF1KE4 WLIGDTSWGSGCAKAYRPGVYGNVMVFTDWIYRQMRADG
:.: .::: :::. .::::..: : :::.
CCDS73 RLVGVVSWGRGCAEPNHPGVYAKVAEFLDWIHDTAQDSLL
410 420 430 440
>>CCDS73391.1 TMPRSS5 gene_id:80975|Hs108|chr11 (413 aa)
initn: 813 init1: 336 opt: 893 Z-score: 793.7 bits: 156.1 E(32554): 6.8e-38
Smith-Waterman score: 893; 35.9% identity (62.3% similar) in 409 aa overlap (86-485:5-405)
60 70 80 90 100 110
pF1KE4 VLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSN
: .: .:.::.... :: .. :.
CCDS73 MRRGCAVLGALGLLAGAGVGSWLLVLYLCPAASQ
10 20 30
120 130 140 150 160 170
pF1KE4 --SGIECDSSGT--CINPSNWCDGVSHCPGGEDENRCVRLYGPNFILQVYSSQRKSWHPV
:: : : : . : . : .. :. . .:.:.. .. : :
CCDS73 PISGTLQDEEITLSCSEASAEEALLPALP----KTVSFRINSEDFLLEAQVRDQPRWLLV
40 50 60 70 80 90
180 190 200 210 220
pF1KE4 CQDDWNENYGRAACRDMGY-KNNFYSSQGIVDDSGSTS--FMKLNTSAGNVDIYKKLYHS
:.. :. : : ..:. . . ... ...: . ..: : .:. :. . .
CCDS73 CHEGWSPALGLQICWSLGHLRLTHHKGVNLTDIKLNSSQEFAQLSPRLGGF-LEEAWQPR
100 110 120 130 140
230 240 250 260 270 280
pF1KE4 DACSSKAVVSLRCIACGVNLNSSRQSRIVGGESALPGAWPWQVSLHVQNVHVCGGSIITP
. :.: :::::: ::. ::::::.:. :: ::::.:. . :.::::...:
CCDS73 NNCTSGQVVSLRCSECGAR---PLASRIVGGQSVAPGRWPWQASVALGFRHTCGGSVLAP
150 160 170 180 190 200
290 300 310 320 330 340
pF1KE4 EWIVTAAHCVEK-PLNNPWHWTAFAGILRQSFMFYGAGYQVEKVISHPNYDSKTKNNDIA
.:.::::::... : : . ::.. .: . : ::..: :: :...... :.:
CCDS73 RWVVTAAHCMHSFRLARLSSWRVHAGLVSHSAVRPHQGALVERIIPHPLYSAQNHDYDVA
210 220 230 240 250 260
350 360 370 380 390 400
pF1KE4 LMKLQKPLTFNDLVKPVCLPNPGMMLQPEQLCWISGWGATEEKGK-TSEVLNAAKVLLIE
:..:: :.:.: : :::: . . . ::.:::: :. . .:..:. . : :.
CCDS73 LLRLQTALNFSDTVGAVCLPAKEQHFPKGSRCWVSGWGHTHPSHTYSSDMLQDTVVPLFS
270 280 290 300 310 320
410 420 430 440 450 460
pF1KE4 TQRCNSRYVYDNLITPAMICAGFLQGNVDSCQGDSGGPLVTSKNNIWWLIGDTSWGSGCA
:: ::: ::.. .:: :.:::.:.: .:.:::::::::: .. : :.: .::: :::
CCDS73 TQLCNSSCVYSGALTPRMLCAGYLDGRADACQGDSGGPLVCPDGDTWRLVGVVSWGRGCA
330 340 350 360 370 380
470 480 490
pF1KE4 KAYRPGVYGNVMVFTDWIYRQMRADG
. .::::..: : :::.
CCDS73 EPNHPGVYAKVAEFLDWIHDTAQDSLL
390 400 410
492 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 00:54:41 2016 done: Sun Nov 6 00:54:41 2016
Total Scan time: 2.650 Total Display time: 0.070
Function used was FASTA [36.3.4 Apr, 2011]